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Search of human proteins with 16418419
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo
sapiens]
(429 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens] 865 0.0
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens] 859 0.0
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens] 657 0.0
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 436 e-122
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens] 344 8e-95
gi|157694526 Fc receptor-like 5 [Homo sapiens] 240 2e-63
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens] 179 6e-45
gi|157057547 Fc receptor-like 6 [Homo sapiens] 119 4e-27
gi|15147240 brother of CDO [Homo sapiens] 68 2e-11
gi|157168355 CD22 molecule [Homo sapiens] 64 3e-10
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 64 3e-10
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 64 3e-10
gi|13489095 sialoadhesin precursor [Homo sapiens] 63 6e-10
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 62 1e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 62 1e-09
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 62 1e-09
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [... 62 1e-09
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [... 62 1e-09
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 62 1e-09
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 62 1e-09
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 61 2e-09
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 61 2e-09
gi|224994173 roundabout 1 isoform d [Homo sapiens] 60 5e-09
gi|224994171 roundabout 1 isoform c [Homo sapiens] 60 5e-09
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 60 5e-09
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 60 5e-09
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 60 5e-09
gi|118572606 hemicentin 1 [Homo sapiens] 59 8e-09
gi|157819143 IgLON family member 5 [Homo sapiens] 59 1e-08
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 58 2e-08
>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
Length = 429
Score = 865 bits (2235), Expect = 0.0
Identities = 429/429 (100%), Positives = 429/429 (100%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
Query: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI 420
TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI 420
Query: 421 TDVDYEDAM 429
TDVDYEDAM
Sbjct: 421 TDVDYEDAM 429
>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
Length = 428
Score = 859 bits (2219), Expect = 0.0
Identities = 428/429 (99%), Positives = 428/429 (99%), Gaps = 1/429 (0%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
Query: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI 420
TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESV AETLGTHMEDKVSLDIYSRLRKANI
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESV-AETLGTHMEDKVSLDIYSRLRKANI 419
Query: 421 TDVDYEDAM 429
TDVDYEDAM
Sbjct: 420 TDVDYEDAM 428
>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
Length = 366
Score = 657 bits (1696), Expect = 0.0
Identities = 337/406 (83%), Positives = 342/406 (84%), Gaps = 55/406 (13%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT----- 295
Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
GRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 296 ----------------------------------GRRSARDPLRSLPSPLPQEFTYLNSP 321
Query: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDK 406
TPGQLQPIYE N+P ++SVA H ++
Sbjct: 322 TPGQLQPIYE----------------NEPREQSVAVHGRQQHSSEQ 351
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 436 bits (1122), Expect = e-122
Identities = 234/403 (58%), Positives = 293/403 (72%), Gaps = 10/403 (2%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L AS P EG PV+L C+ Q D Q QFCFFR+ + LG GWSSSP+LQI+A+W E
Sbjct: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170
Query: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
DTGSYWC+A+T+ ++ + S +SQI+V R+P+++VSLE + PGGQV EG +L+L+CSVA
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
GTG++TF WY+ A G ++ KTQRSL+AE EIP+V+ESDA +YYC A+NG+ P S +V+
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
I VRIPVSRP+L LR+P AQAAV D+LELHCEALRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 291 IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
Query: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLG 318
GASFNLSLT EHSGNYSCEANNGLGAQ SEAV ++ + P G R + +T+GV+ GL LG
Sbjct: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLG 410
Query: 319 PATVALLFCYGLKRKI-GRRSARDPLRSLPSPLPQEFTYLNSPTPG--QLQPIYENVNVV 375
VALL Y L KI G SA + R P PQEFTY +SPTP +LQP+Y NV V
Sbjct: 411 FTGVALLL-YALFHKISGESSATNEPRGASRPNPQEFTY-SSPTPDMEELQPVYVNVGSV 468
Query: 376 SGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKA 418
D VYS + Q + S TL +E+K S IYS ++K+
Sbjct: 469 DVDVVYSQVWSMQQPESSANIRTL---LENKDSQVIYSSVKKS 508
Score = 54.3 bits (129), Expect = 2e-07
Identities = 72/306 (23%), Positives = 122/306 (39%), Gaps = 19/306 (6%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
ML LL+I + E A+ + +PS EG + L C+ Q+ Q + + +D +
Sbjct: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGE--QNWKIQ-KMAYHKDNKE 57
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L S L I + D+G+Y+C T L + S I +V
Sbjct: 58 LSVFKKFSDFL-IQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
Query: 121 GGQVMEGDRLVLICSVAMGTG----DITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
Q +EG + L C + + F +++ N + S + E +I +V
Sbjct: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRE----NQVLGSGWSSSPELQISAVWSE 170
Query: 177 DAEQYYCVAENGYGPSPSGLVSITV---RIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
D Y+C AE + + RIP+S L +RAP Q L L C
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
Query: 234 GSPPILYWFYHE--DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
G+ + + +Y E ++G ++ S ++ E +G Y C A+NG +S+ V
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
Query: 292 LNFTVP 297
+ +P
Sbjct: 291 IPVRIP 296
>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
Length = 734
Score = 344 bits (883), Expect = 8e-95
Identities = 172/279 (61%), Positives = 209/279 (74%), Gaps = 2/279 (0%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L AS S P EGSP+TLTC+ Q D Q QF FRD++ LG GWS SP+LQI AMW E
Sbjct: 194 LRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTE 253
Query: 80 DTGSYWCEAQTMASKVL-RSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
D+GSYWCE +T+ + RS RSQI V RVPV++V+LE +P GGQ++EG+ +VLICSVA
Sbjct: 254 DSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ 313
Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
G+G +TF W+K +L KTQRSL AE + +V+ESDA +YYC A+N + P S +
Sbjct: 314 GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIR 373
Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
+TVRIPVS P+L RAPRA V D+LELHCE+LRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 374 VTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGG 433
Query: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
GASFNLSLT EHSGNYSC+A+NGLGAQ S V+L TVP
Sbjct: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVP 472
Score = 231 bits (589), Expect = 1e-60
Identities = 166/415 (40%), Positives = 220/415 (53%), Gaps = 35/415 (8%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSS--PKLQIAAMWKEDTGSYWCE 87
EG + L C + S F + R+LG S +L + + + D G Y+C
Sbjct: 301 EGENMVLICSVA-QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCA 359
Query: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
A + S +L S ++ V R+PV+ L + P + GD L L C G+ I + +
Sbjct: 360 ADNVHSPIL-STWIRVTV-RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRF 417
Query: 148 YKGAVGLNLQSKTQR-------SLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
Y V L S SLTAE+ + Y C A+NG G S VS+
Sbjct: 418 YHEDVTLGNSSAPSGGGASFNLSLTAEH---------SGNYSCDADNGLGAQHSHGVSLR 468
Query: 201 VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGA 260
V +PVSRP+L LRAP AQA V D+LELHCE+LRGS PILYWFYHED TLG+ SA SGGGA
Sbjct: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
Query: 261 SFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPA 320
SFNLSLT EHSGNYSCEA+NGLGAQ S+ VTLN T + R+ +G+ +LS L A
Sbjct: 529 SFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLA 588
Query: 321 TVALLFCYG-LKRKIGRRSA-----------RDPLRSLPSPL-PQEFTYLNSPTPGQLQP 367
A L Y +RK G SA ++P S PS + PQE T+ P +L+P
Sbjct: 589 AAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEP 648
Query: 368 IYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANITD 422
+Y NVN + +YS + Q +E+ +A H E + +YS L+K + D
Sbjct: 649 MYSNVNPGDSNPIYSQIWSIQHTKEN-SANCPMMHQEHEELTVLYSELKKTHPDD 702
>gi|157694526 Fc receptor-like 5 [Homo sapiens]
Length = 977
Score = 240 bits (613), Expect = 2e-63
Identities = 170/420 (40%), Positives = 226/420 (53%), Gaps = 22/420 (5%)
Query: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP--- 63
L + P+ P L L + G + L C+ P + F+ + LG
Sbjct: 557 LFVTVPVSRPI-LTLRVPRAQAVVGDLLELHCEAP---RGSPPILYWFYHEDVTLGSSSA 612
Query: 64 --GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHR-VPVADVSLETQPP 120
G +S L + A E +G+Y CEA + ++ I++ VPV+ L + P
Sbjct: 613 PSGGEASFNLSLTA---EHSGNYSCEAN---NGLVAQHSDTISLSVIVPVSRPILTFRAP 666
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Q + GD L L C G+ I + +Y V L S A + + S+ +
Sbjct: 667 RAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG-GASFNL-SLTTEHSGI 724
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Y C A+NG S +V++ V +PVSRP+L LRAP AAV D+LELHCEALRGSP ILY
Sbjct: 725 YSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILY 784
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
F+HED+TLG+RS+PSGG AS NLSLT EHSGNYSCEA+NGLGAQRSE VTL T T
Sbjct: 785 RFFHEDVTLGNRSSPSGG-ASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTAN 843
Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
RS +GV GLLS G A ALL L RK GR+ A DP RS QE TY N P
Sbjct: 844 RSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVP 903
Query: 361 TPGQLQPIYENVNVVSGDEVYS-LAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKAN 419
+LQP+Y N N + VYS + + ++ +VA++ H+ +K S IYS ++ A+
Sbjct: 904 AWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDP--RHLRNKGSPIIYSEVKVAS 961
Score = 211 bits (538), Expect = 8e-55
Identities = 122/280 (43%), Positives = 161/280 (57%), Gaps = 7/280 (2%)
Query: 21 LIASPSHPTEGSPVTLTCKMPF-LQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L AS P G+PVTLTC+ L+ SD +F FFRD + LG GWS SP QI AMW +
Sbjct: 194 LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSK 253
Query: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
D+G YWC+A TM V+ S RS I V ++P + L P EG ++ L C
Sbjct: 254 DSGFYWCKAATMPYSVISDSPRSWIQV-QIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312
Query: 139 GTGDITFLWYKGAVGLNLQS-KTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
+ + +Y V L +S + +R + + S+ ++ YYC A+NG G PS V
Sbjct: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISF---SLTTENSGNYYCTADNGLGAKPSKAV 369
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
S++V +PVS P+L L +P + LHCEA RGS PILY F+HE L RSA S
Sbjct: 370 SLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA 429
Query: 258 GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
GG + + SLT EHSGNY C A+NG G QRS+AV+L+ TVP
Sbjct: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVP 469
Score = 203 bits (516), Expect = 3e-52
Identities = 124/270 (45%), Positives = 161/270 (59%), Gaps = 9/270 (3%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-GWSSSPKLQIA-AMWKEDTGSYWCE 87
EG+ VTL C+ Q + F + AL +S+ + I+ ++ E +G+Y+C
Sbjct: 393 EGAKVTLHCEA---QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCT 449
Query: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
A RS+ ++V VPV+ L EG + L C V G+ I + +
Sbjct: 450 ADNGFGPQ-RSKAVSLSV-TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQF 507
Query: 148 YKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
Y + L S + S+ S+ E + YYC A+NG+GP S +VS+ V +PVSR
Sbjct: 508 YHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565
Query: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
PIL LR PRAQA V D+LELHCEA RGSPPILYWFYHED+TLGS SAPSGG ASFNLSLT
Sbjct: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT 625
Query: 268 EEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
EHSGNYSCEANNGL AQ S+ ++L+ VP
Sbjct: 626 AEHSGNYSCEANNGLVAQHSDTISLSVIVP 655
Score = 198 bits (503), Expect = 9e-51
Identities = 130/296 (43%), Positives = 168/296 (56%), Gaps = 16/296 (5%)
Query: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
L + P+ P L L ++ + EG+ VTL C++ Q Q + F+ + L WS
Sbjct: 464 LSVTVPVSHPV-LTLSSAEALTFEGATVTLHCEV---QRGSPQILYQFYHEDMPL---WS 516
Query: 67 SSP----KLQIA-AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
SS ++ + ++ + +G+Y+C A RS + V VPV+ L + P
Sbjct: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ-RSEVVSLFV-TVPVSRPILTLRVPR 574
Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Q + GD L L C G+ I + +Y V L S A + + S+ + Y
Sbjct: 575 AQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGG-EASFNL-SLTAEHSGNY 632
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
C A NG S +S++V +PVSRPIL RAPRAQA V D+LELHCEALRGS PILYW
Sbjct: 633 SCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692
Query: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
FYHED+TLG SAPSGGGASFNLSLT EHSG YSCEA+NGL AQRSE VTL VP
Sbjct: 693 FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVP 748
Score = 95.9 bits (237), Expect = 6e-20
Identities = 90/326 (27%), Positives = 140/326 (42%), Gaps = 35/326 (10%)
Query: 11 APLCEPAEL------FLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG 64
+PL P L ++ +P EG V L C+ ++ +++ L
Sbjct: 90 SPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA----KAEVTLNNTIYKNDNVLA-F 144
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+ I +D G+Y C + + S +I V V + Q
Sbjct: 145 LNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPV---LRASSFQP 201
Query: 125 MEGDRLVLIC----SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G+ + L C S+ + F +++ L L SL+ ++I ++ D+
Sbjct: 202 ISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW----SLSPNFQITAMWSKDSGF 257
Query: 181 YYCVAENGYGPSPSGLVS------ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
Y+C A P ++S I V+IP S P+L L +A + LHCE
Sbjct: 258 YWCKAAT----MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQED 313
Query: 235 SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
S LY FYHE + L +S GAS + SLT E+SGNY C A+NGLGA+ S+AV+L+
Sbjct: 314 SLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSV 373
Query: 295 TVPTGARSNHLTSG---VIEGLLSTL 317
TVP +L+S + EG TL
Sbjct: 374 TVPVSHPVLNLSSPEDLIFEGAKVTL 399
Score = 29.3 bits (64), Expect = 7.2
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESD 177
QPP V +G+R+ L C WY +G + +T + I V+ES
Sbjct: 28 QPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDN------ILEVQESG 81
Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEA 231
+Y C A+ SP V + S L+L+AP + + V+ L C A
Sbjct: 82 --EYRCQAQGSPLSSP-------VHLDFSSASLILQAPLSVFEGDSVV-LRCRA 125
>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
Length = 515
Score = 179 bits (453), Expect = 6e-45
Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 2/184 (1%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L A+ S PTEG+ V L+C+ + SD F FFRD + WS+ P+LQ+ +W+E
Sbjct: 195 LKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRE 254
Query: 80 DTGSYWCEAQTMASKVLRSRRS-QINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
++GSYWC A+T+ + + S QI+V R+PV+ V LETQP GGQ +EG+ LVL+CSVA
Sbjct: 255 NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314
Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
GTGD TF W++ + +L KTQRSL AE E+P++R+S A YYC A+N YGP S +++
Sbjct: 315 GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374
Query: 199 ITVR 202
+TVR
Sbjct: 375 VTVR 378
Score = 94.0 bits (232), Expect = 2e-19
Identities = 79/256 (30%), Positives = 123/256 (48%), Gaps = 9/256 (3%)
Query: 167 EYEIPSVRESDAEQYYCVAE----NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE 222
E ++P+V ++ Y+C AE N + SPS + + RIPVS +L + QA
Sbjct: 245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ-RIPVSGVLLETQPSGGQAVEG 303
Query: 223 DVLELHCEALRGSPPILYWFYHEDI--TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANN 280
++L L C G+ + ++ ED+ +LG ++ S ++ + H+G Y C A+N
Sbjct: 304 EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADN 363
Query: 281 GLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSAR 340
G +S + + G R + +G GLLS L A VALLF +RK G
Sbjct: 364 SYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLA-VALLFHCWRRRKSGVGFLG 422
Query: 341 DPLRSLPSPLPQEFTYLNSPTPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLG 400
D R P+P P E ++ P +LQ +Y +V+ GD VYS Q +E A T
Sbjct: 423 DETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEE-EANTSR 481
Query: 401 THMEDKVSLDIYSRLR 416
T +EDK +YS ++
Sbjct: 482 TLLEDKDVSVVYSEVK 497
>gi|157057547 Fc receptor-like 6 [Homo sapiens]
Length = 434
Score = 119 bits (299), Expect = 4e-27
Identities = 117/393 (29%), Positives = 176/393 (44%), Gaps = 39/393 (9%)
Query: 19 LFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWK 78
L+L A P+ EG +TL C+ + Q F+RD + L + L + A
Sbjct: 20 LYLQAWPNPVFEGDALTLRCQG---WKNTPLSQVKFYRDGKFLHFS-KENQTLSMGAATV 75
Query: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLICSVA 137
+ G Y C Q M ++ S+ + +V + + + P + EG + L C
Sbjct: 76 QSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTK 135
Query: 138 M----GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC--VAENGYGP 191
+ + F ++K G LQ R E IP +E D+ Y+C E G
Sbjct: 136 LHPLRSALRLLFSFHKD--GHTLQD---RGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQ 190
Query: 192 SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGS 251
S + + V+ PVSRP+L L A AV D+++L CEA RGSPPILY FY ++ +G+
Sbjct: 191 KQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGN 250
Query: 252 RSAPSGGGASFNLSL-TEEHSGNYSCEANNGLGAQRSEAVTLNF---TVPTGARSNHLTS 307
SAP GG S + +E+ +GNYSCEA N + +RSE L+ V SN L
Sbjct: 251 HSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVP 310
Query: 308 GVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQP 367
+ LL + A L++ RK G LPS +P + G+ P
Sbjct: 311 WLPASLLGLMVIAAALLVYVRSW-RKAG---------PLPSQIPP------TAPGGEQCP 354
Query: 368 IYENVNVVSGDE---VYSLAYYNQPEQESVAAE 397
+Y NV+ G + VYS+ + E+ +AE
Sbjct: 355 LYANVHHQKGKDEGVVYSVVHRTSKRSEARSAE 387
>gi|15147240 brother of CDO [Homo sapiens]
Length = 1114
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/266 (25%), Positives = 110/266 (41%), Gaps = 19/266 (7%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG---WSSSPKLQIAAMWKEDTGSYWC 86
EG+ + C +P AQ ++ ++ G S LQI +ED G Y C
Sbjct: 142 EGNTAVIACHLPESHPK-AQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKC 200
Query: 87 EAQTMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQ---VMEGDRLVLICSVAMGTGD 142
A ++ +++ S + R A+ + PP Q V +G L+L C VA G
Sbjct: 201 AAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILEC-VASGIPP 259
Query: 143 ITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVR 202
W K + +KT R L + I + E D+ Y C+A+NG G + ++ V+
Sbjct: 260 PRVTWAKDGSSVTGYNKT-RFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQ 318
Query: 203 I----PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
+ V+ + L P Q+A +L CE PP + W + + S+
Sbjct: 319 VFEPPEVTMELSQLVIPWGQSA-----KLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSR 373
Query: 259 GASFNLSLTEEHSGNYSCEANNGLGA 284
A LS+ E G Y C A N +G+
Sbjct: 374 RALRVLSMGPEDEGVYQCMAENEVGS 399
Score = 32.7 bits (73), Expect = 0.65
Identities = 54/238 (22%), Positives = 82/238 (34%), Gaps = 21/238 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I A+ G Y C A+ A V + V + D L+ Q +V EG+
Sbjct: 91 LVITALNNHTVGRYQCVARMPAGAVASVPAT---VTLANLQDFKLDVQHVI-EVDEGNTA 146
Query: 131 VLICSV------AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
V+ C + A + W + + G L + +I + + D Y C
Sbjct: 147 VIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPS-----GNLQIVNASQEDEGMYKCA 201
Query: 185 AENGYGPSPSGLVS---ITVRIPVSRPILMLRAPRAQAAVE---DVLELHCEALRGSPPI 238
A N S + VR + ++ P AQ + L L C A PP
Sbjct: 202 AYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPR 261
Query: 239 LYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
+ W G + +EE SG Y C A+NG+G + + N V
Sbjct: 262 VTWAKDGSSVTGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQV 319
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 63.9 bits (154), Expect = 3e-10
Identities = 70/301 (23%), Positives = 106/301 (35%), Gaps = 52/301 (17%)
Query: 22 IASPSHPTEGSPVTLTCKMPF----------------------LQSSDAQFQFCFFRDTR 59
I P E VTLTC + F + S+ + F R
Sbjct: 145 IQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEGVPMRQAAVTSTSLTIKSVFTRSEL 204
Query: 60 ALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
P WS K+ C+ Q K L + Q+NV P ++ + P
Sbjct: 205 KFSPQWSHHGKIVT------------CQLQDADGKFLSNDTVQLNVKHTPKLEIKVT--P 250
Query: 120 PGGQVMEGDRLVLICSVAMGTGDITFL-WYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
V EGD + + C V+ + T + W K L Q+ T + V + +
Sbjct: 251 SDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQN------TFTLNLREVTKDQS 304
Query: 179 EQYYCVAENGYGPSPSGLVSITVRI-PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
+Y C N GP S V + V+ P + +L +P + + + L C +L P
Sbjct: 305 GKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEGSQVEFL---CMSLANPLP 361
Query: 238 ILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTLNFTV 296
Y +YH + R+ + H+G YSC A N LG QR L+
Sbjct: 362 TNYTWYHNGKEMQGRTEEK----VHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQY 417
Query: 297 P 297
P
Sbjct: 418 P 418
Score = 43.9 bits (102), Expect = 3e-04
Identities = 63/282 (22%), Positives = 106/282 (37%), Gaps = 41/282 (14%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAM---- 76
+I +P EG VTL+C S ++++ G P L + +
Sbjct: 425 VIQNPMPIREGDTVTLSCNYNSSNPSVTRYEW--------KPHGAWEEPSLGVLKIQNVG 476
Query: 77 WKEDT-----GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
W T + WC + AS V +NV P DV + P ++ G+ +
Sbjct: 477 WDNTTIACAACNSWC---SWASPVA------LNVQYAP-RDVRVRKIKPLSEIHSGNSVS 526
Query: 132 LICSVAMG-TGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
L C + ++ F W K L +S + S+ DA Y C N G
Sbjct: 527 LQCDFSSSHPKEVQFFWEKNGRLLGKES--------QLNFDSISPEDAGSYSCWVNNSIG 578
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLG 250
+ S ++ V + R + + +P Q L CE+ +PP+ ++ + +
Sbjct: 579 QTASKAWTLEV-LYAPRRLRVSMSPGDQVMEGKSATLTCES-DANPPVSHYTWFD---WN 633
Query: 251 SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
++S P + +HSG Y C+ N +G RS TL
Sbjct: 634 NQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTL 675
Score = 36.6 bits (83), Expect = 0.045
Identities = 61/305 (20%), Positives = 124/305 (40%), Gaps = 24/305 (7%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
EP+ + ++ SP+ EGS V C ++ + ++ + + + + K+ I
Sbjct: 332 EPSTVQILHSPA--VEGSQVEFLCMS---LANPLPTNYTWYHNGKEMQG--RTEEKVHIP 384
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLIC 134
+ G+Y C A+ + R ++++V P ++ P + EGD + L C
Sbjct: 385 KILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPKKVTTVIQNPM--PIREGDTVTLSC 442
Query: 135 SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPS 194
+ +T +K + +I +V D C A N + S +
Sbjct: 443 NYNSSNPSVTRYEWKP------HGAWEEPSLGVLKIQNVGW-DNTTIACAACNSWC-SWA 494
Query: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
V++ V+ + P ++ + + L C+ P + +F+ ++ L + +
Sbjct: 495 SPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKNGRLLGKES 554
Query: 255 PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSG--VIEG 312
+F+ S++ E +G+YSC NN +G S+A TL ++ G V+EG
Sbjct: 555 Q----LNFD-SISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 313 LLSTL 317
+TL
Sbjct: 610 KSATL 614
Score = 32.3 bits (72), Expect = 0.85
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 9/118 (7%)
Query: 200 TVRIPVSR-PILMLRAPRAQAAVE--DVLELHCEALRGSPPILYWFYHEDITLGSRSAPS 256
TV++ V P L ++ + A V D + + CE +P + +D T S
Sbjct: 233 TVQLNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGT----SLKK 288
Query: 257 GGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNFT-VPTGARSNHLTSGVIEG 312
+ NL +T++ SG Y C+ +N +G RSE V L P + L S +EG
Sbjct: 289 QNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEG 346
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 63.9 bits (154), Expect = 3e-10
Identities = 73/270 (27%), Positives = 108/270 (40%), Gaps = 27/270 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P SSS KL+I A + D G+Y C A S Q+ V P T+ P
Sbjct: 623 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL-----TELP 675
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKG-------AVGLNLQSKTQRSLTAEYEIPSV 173
+E R L+ A G T W +G +G S++++ + SV
Sbjct: 676 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 735
Query: 174 RESDAEQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
D Y C A N +G + +T P P + AP + + L C L
Sbjct: 736 APEDQAPYVCEARNVFGKVQAEARLIVTGHAP---PQIASSAPTVRVLEGQPVSLPCIVL 792
Query: 233 RGSP-PILYWFYH-EDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
G P P +W + GSR + G+ +EH+G YSC A N G+Q + V
Sbjct: 793 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRD-V 851
Query: 291 TLNFTVPT---GARSNHLTSGVIEGLLSTL 317
L VP ++H+T+ EG+ ++L
Sbjct: 852 ELVVQVPPRIHPTATHHITN---EGVPASL 878
Score = 60.5 bits (145), Expect = 3e-09
Identities = 66/252 (26%), Positives = 101/252 (40%), Gaps = 24/252 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I + ED G+Y C+A + + + + + ++ VS V G+
Sbjct: 545 LIIQGVAPEDAGNYSCQA----TNEVGTDQETVTLYYTDPPSVSAVNAVV--LVAVGEEA 598
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
VL+C A G +WY+G GL + + S + + IP+ +E DA Y C A N G
Sbjct: 599 VLVCE-ASGVPPPRVIWYRG--GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 655
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
+ S +++ V + PR + L C A PP + W + L
Sbjct: 656 DA-----SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 710
Query: 250 G--------SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA-VTLNFTVPTGA 300
G SRS G F S+ E Y CEA N G ++EA + + P
Sbjct: 711 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQI 770
Query: 301 RSNHLTSGVIEG 312
S+ T V+EG
Sbjct: 771 ASSAPTVRVLEG 782
Score = 42.4 bits (98), Expect = 8e-04
Identities = 61/263 (23%), Positives = 96/263 (36%), Gaps = 21/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYW 85
G L+C++ +A + + RD R L + L+I+ + D G Y
Sbjct: 414 GETAVLSCRV----LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 469
Query: 86 CEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITF 145
C A A+ V R+ + V P + +Q +G + + CS A G
Sbjct: 470 CVASN-ANGVTRAS-VWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCS-ASGYPTPHI 522
Query: 146 LWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
W + + L S+ I V DA Y C A N G ++T+
Sbjct: 523 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQE---TVTLYYTD 579
Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
+ + A A E+ + L CEA PP + W Y + + S G +
Sbjct: 580 PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIW-YRGGLEMILAPEGSSSGKLRIPA 637
Query: 266 LTEEHSGNYSCEANNGLGAQRSE 288
E +G Y+C A N LG +E
Sbjct: 638 AQERDAGTYTCRAVNELGDASAE 660
Score = 38.9 bits (89), Expect = 0.009
Identities = 77/299 (25%), Positives = 109/299 (36%), Gaps = 60/299 (20%)
Query: 16 PAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK----L 71
P ++ A EG PV+L C + + + + +D R L PG S + L
Sbjct: 767 PPQIASSAPTVRVLEGQPVSLPC---IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSL 823
Query: 72 QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINV----HRVPVADVSLETQPPGGQVMEG 127
+ +E G Y C A A R + V H ++ E P
Sbjct: 824 HLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPAS------ 877
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQ------SKTQRSLTAEYEIPSVRESDAEQY 181
L C VA G T W K L + SK L A+ PS + DA Y
Sbjct: 878 ----LPC-VASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQ---PSAQ--DAGAY 927
Query: 182 YCVAENGYGPSPSGLVSITVRIPVS-RPILMLRAPR-------AQAAVEDVLELHCEALR 233
C A N G S S +R+ V+ +P + + R A + + L CEA
Sbjct: 928 VCTATNTVGFS-----SQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKG 982
Query: 234 GSPPILYWFYHEDITLGSRSAPS-----GGGASFNLSLTEEH---SGNYSCEANNGLGA 284
PP++ W T SR P G S +L L + SG+Y C A+N G+
Sbjct: 983 SPPPLVTW------TKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGS 1035
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 63.9 bits (154), Expect = 3e-10
Identities = 73/270 (27%), Positives = 108/270 (40%), Gaps = 27/270 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P SSS KL+I A + D G+Y C A S Q+ V P T+ P
Sbjct: 740 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL-----TELP 792
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKG-------AVGLNLQSKTQRSLTAEYEIPSV 173
+E R L+ A G T W +G +G S++++ + SV
Sbjct: 793 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 852
Query: 174 RESDAEQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
D Y C A N +G + +T P P + AP + + L C L
Sbjct: 853 APEDQAPYVCEARNVFGKVQAEARLIVTGHAP---PQIASSAPTVRVLEGQPVSLPCIVL 909
Query: 233 RGSP-PILYWFYH-EDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
G P P +W + GSR + G+ +EH+G YSC A N G+Q + V
Sbjct: 910 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRD-V 968
Query: 291 TLNFTVPT---GARSNHLTSGVIEGLLSTL 317
L VP ++H+T+ EG+ ++L
Sbjct: 969 ELVVQVPPRIHPTATHHITN---EGVPASL 995
Score = 60.8 bits (146), Expect = 2e-09
Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 16/224 (7%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+IA ED G+Y C A+ A + R + V V +E P EG
Sbjct: 4001 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 4054
Query: 130 LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C A G+ + W K G + K + E + ++ DA Y C AEN
Sbjct: 4055 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 4113
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
G + + + +PV + R+ R + D L L C A RGSP P + W ++
Sbjct: 4114 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 4168
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
S GG +++ E SG Y C A N +G R++AV+
Sbjct: 4169 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVS 4210
Score = 60.5 bits (145), Expect = 3e-09
Identities = 66/252 (26%), Positives = 101/252 (40%), Gaps = 24/252 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I + ED G+Y C+A + + + + + ++ VS V G+
Sbjct: 662 LIIQGVAPEDAGNYSCQA----TNEVGTDQETVTLYYTDPPSVSAVNAVV--LVAVGEEA 715
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
VL+C A G +WY+G GL + + S + + IP+ +E DA Y C A N G
Sbjct: 716 VLVCE-ASGVPPPRVIWYRG--GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 772
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
+ S +++ V + PR + L C A PP + W + L
Sbjct: 773 DA-----SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 827
Query: 250 G--------SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA-VTLNFTVPTGA 300
G SRS G F S+ E Y CEA N G ++EA + + P
Sbjct: 828 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQI 887
Query: 301 RSNHLTSGVIEG 312
S+ T V+EG
Sbjct: 888 ASSAPTVRVLEG 899
Score = 60.1 bits (144), Expect = 4e-09
Identities = 68/245 (27%), Positives = 94/245 (38%), Gaps = 25/245 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P LQ+ A+ D+G+Y C A + A + R Q+ V P + S QP
Sbjct: 3448 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 3503
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G + L+C A GT W+K L R+ +R DA
Sbjct: 3504 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 3556
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
Y C+AE SP+G + + R+ V P I+ R PR L L C P
Sbjct: 3557 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 3611
Query: 238 ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
+ W H D + A P G +L+ SG+YSC A N G+
Sbjct: 3612 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 3669
Query: 294 FTVPT 298
TVPT
Sbjct: 3670 HTVPT 3674
Score = 55.5 bits (132), Expect = 9e-08
Identities = 61/246 (24%), Positives = 93/246 (37%), Gaps = 19/246 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
LQ AA+ +ED+G+Y C A+ + S ++V PV S +P GG +
Sbjct: 4182 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 4237
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C V G W K + L + I DA +Y C+AEN
Sbjct: 4238 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 4292
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + + + + S P+ + D + L C+A P + W
Sbjct: 4293 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 4348
Query: 248 TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
SR + S L E +G Y C A+N LG+ + A + P G+ +
Sbjct: 4349 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS--M 4406
Query: 307 SGVIEG 312
+GVI G
Sbjct: 4407 TGVING 4412
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G+Y CE + S+ Q+ VH P ++ +PP + D + + A G
Sbjct: 2231 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 2286
Query: 142 DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
T W + +GL LQ++ Q + + + +Y CVAEN G +
Sbjct: 2287 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 2341
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
++V +P + AA+ L L CEA+ PP + WF E+ ++ G +
Sbjct: 2342 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 2400
Query: 255 PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
GG ++ T+E SG YSC A+N G R
Sbjct: 2401 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 2433
Score = 53.9 bits (128), Expect = 3e-07
Identities = 65/256 (25%), Positives = 96/256 (37%), Gaps = 26/256 (10%)
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+S P LQI + D G Y C A +A + R ++ V ++E P V
Sbjct: 1844 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 1897
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
+E + L C +A G W+KG ++ S+ I + SDA Y C
Sbjct: 1898 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 1956
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
VA N G + + +R+ V I + + V + L C A P L W
Sbjct: 1957 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 2013
Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
G+ +P+G GG L S SG YSC A + +G R + V L
Sbjct: 2014 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQV 2067
Query: 295 TVPTGARSNHLTSGVI 310
+P L V+
Sbjct: 2068 HMPPSILGEELNVSVV 2083
Score = 52.4 bits (124), Expect = 8e-07
Identities = 77/291 (26%), Positives = 109/291 (37%), Gaps = 37/291 (12%)
Query: 32 SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
+PV LTC P + S A Q A G G+ SP L+I G Y
Sbjct: 3872 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 3925
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A+ A + + + V PV ++ P + + + ++L C A G T
Sbjct: 3926 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 3978
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
W K + + TQ + I DA Y C+A+N G S G + V++P
Sbjct: 3979 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 4037
Query: 205 VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
P++ P L C+A RGSP P + W G+ PSG
Sbjct: 4038 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 4093
Query: 260 ASFNLSLTEEHSGNYSCEANNGLGAQRSEA-----VTLNFTVPTGARSNHL 305
NL + +G Y+C A N +G R V FT G RS L
Sbjct: 4094 LVKNLE--GQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL 4142
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 35/240 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV------ 124
LQI KED G Y C + ++ N H + S+ P G+V
Sbjct: 2597 LQILNAQKEDAGQYTCVVTNELGEAVK------NYHVEVLIPPSISKDDPLGEVGVKEVK 2650
Query: 125 -MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYY 182
L L C + T WYK + S+ Q +I + SD+ +Y
Sbjct: 2651 TKVNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 2709
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE-------- 226
CVA N G + P+ + + ++ R A+ V + E
Sbjct: 2710 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY 2769
Query: 227 LHCEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
L+C+ PP L W Y ED ++ G + GG + L E++G YSC+A+N +G
Sbjct: 2770 LYCDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 2828
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
+P EL L T G+P+ L C Q + +D +AL ++S ++
Sbjct: 3501 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 3549
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
+ D G Y C A++ A + +S R ++ V P G + + G +LV
Sbjct: 3550 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 3600
Query: 132 LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
L CSV A IT W++ + L + TQ + ++ ++ +D+ Y C A N
Sbjct: 3601 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 3657
Query: 190 GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G S+ R+ + P + P +V L C+A P++ W + +
Sbjct: 3658 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 3712
Query: 249 LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
L RS P G S + + + +G+Y C A+N G+ R
Sbjct: 3713 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 3753
Score = 47.4 bits (111), Expect = 3e-05
Identities = 67/249 (26%), Positives = 98/249 (39%), Gaps = 39/249 (15%)
Query: 64 GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ 123
G S L++A + D+G Y C A A S R + V P ++ P +
Sbjct: 1077 GLLPSGSLRLAQVQVGDSGHYECTASNPAGSA--SHRYVLGVQVPP----QVQPGPRVLK 1130
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
V+ G+ L L C VA G + W K V L R ++R SDA +Y C
Sbjct: 1131 VLVGEALDLNC-VAEGNPEPQLSWSKDGVVLQ-----GRGPQGSVHFAAIRTSDAGRYRC 1184
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVL----ELHCEALRGSP-PI 238
A N +G+ + V + V P A +E V L C A RG+P P
Sbjct: 1185 EASNS-----AGVDAWEVELRVLEPPHW-GADETSGLLERVAGENASLPCPA-RGTPKPQ 1237
Query: 239 LYWFYHEDITLGSRSAPSGG---------GASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+ W G S P G G+ F S++ SG+Y C+A N +G+ A
Sbjct: 1238 VTW------RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRA 1291
Query: 290 VTLNFTVPT 298
+ + P+
Sbjct: 1292 KLVVYVPPS 1300
Score = 46.6 bits (109), Expect = 4e-05
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 20/249 (8%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+I D G Y C+ +A + +R+ + +VP + +T+ + G
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV---QVPPTFENPKTETV--SQVAGSP 3141
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA---EYEIPSVRESDAEQYYCVAE 186
LVL C V+ G T W K + ++S + + ++ ++ + A Y CVAE
Sbjct: 3142 LVLTCDVS-GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 3198
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
N + V + P R + R E + L CEA PP + W +
Sbjct: 3199 NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQE--VRLDCEADGQPPPDVAWL-KDG 3255
Query: 247 ITLGSRSAPS-----GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
LG P GG+ L +G Y+C A+N G + + T+N VP +
Sbjct: 3256 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVPPTIK 3314
Query: 302 SNHLTSGVI 310
SG +
Sbjct: 3315 QGADGSGTL 3323
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+LQ+ D G Y C+A ++ R + V P +P + + G
Sbjct: 1557 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 1613
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
+ L C VA G T W+ GL + + L + + S E+ + Y CVA
Sbjct: 1614 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 1670
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
+ P+ ++ +V + V +L+ + V LEL C+A P + W +
Sbjct: 1671 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 1727
Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
E++ G + A G + ++ E +HSG ++C+A N G +E
Sbjct: 1728 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 1772
Score = 43.9 bits (102), Expect = 3e-04
Identities = 66/280 (23%), Positives = 105/280 (37%), Gaps = 19/280 (6%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
E +P L C + D ++R+ + L G S LQI + E+ G Y
Sbjct: 2764 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 2819
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C+A + ++ V PV E V + L C A+G T
Sbjct: 2820 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 2876
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
W + + + + Q + ++ + +DA Y CVAEN G S T+R+
Sbjct: 2877 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 2933
Query: 204 PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
V I L + A + + L C+ P + W+ + ++LG G +
Sbjct: 2934 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 2993
Query: 263 NLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
L SG Y+CEA N G + + V L+ VP R
Sbjct: 2994 QLGRARLSDSGMYTCEALNAAGRDQ-KLVQLSVLVPPAFR 3032
Score = 42.4 bits (98), Expect = 8e-04
Identities = 61/263 (23%), Positives = 96/263 (36%), Gaps = 21/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYW 85
G L+C++ +A + + RD R L + L+I+ + D G Y
Sbjct: 531 GETAVLSCRV----LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 586
Query: 86 CEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITF 145
C A A+ V R+ + V P + +Q +G + + CS A G
Sbjct: 587 CVASN-ANGVTRAS-VWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCS-ASGYPTPHI 639
Query: 146 LWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
W + + L S+ I V DA Y C A N G ++T+
Sbjct: 640 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQE---TVTLYYTD 696
Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
+ + A A E+ + L CEA PP + W Y + + S G +
Sbjct: 697 PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIW-YRGGLEMILAPEGSSSGKLRIPA 754
Query: 266 LTEEHSGNYSCEANNGLGAQRSE 288
E +G Y+C A N LG +E
Sbjct: 755 AQERDAGTYTCRAVNELGDASAE 777
Score = 38.5 bits (88), Expect = 0.012
Identities = 63/277 (22%), Positives = 117/277 (42%), Gaps = 21/277 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
GSP+ LTC + + + + + ++ A+ S +LQ++ + G+Y C A+
Sbjct: 3139 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 3198
Query: 90 TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
++ + + V R+ + V+ E V+EG + L C D+ +L
Sbjct: 3199 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 3253
Query: 148 YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
+G ++ + L + +R SDA Y CVA N G + L ++ V +P
Sbjct: 3254 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 3310
Query: 207 RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
P + A + V +++ + C +RGSPPI + + + L R+ G G +
Sbjct: 3311 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 3368
Query: 262 FNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
+S + +G ++C A + G TL VP
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAGV-ADRNFTLQVQVP 3404
Score = 28.9 bits (63), Expect = 9.4
Identities = 61/238 (25%), Positives = 85/238 (35%), Gaps = 34/238 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L +A++ D+G Y C+A SRR+++ V+ P + + + M G L
Sbjct: 1263 LFLASVSPADSGDYECQATNEVGST--SRRAKLVVYVPP--SIREDGRKANVSGMAGQSL 1318
Query: 131 VLICSVAMGTGDITFLWYKGA--VGLNL------------QSKTQRSLTAEYEI--PSVR 174
L C A G +W K A VG+ L Q R L + P ++
Sbjct: 1319 TLECD-ANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQ 1377
Query: 175 ESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQ----AAVEDVLELHCE 230
E D+ Y C AEN +G + V P +L A AQ A DV EL C
Sbjct: 1378 EGDSGLYSCRAEN-----QAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADV-ELQCW 1431
Query: 231 ALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH---SGNYSCEANNGLGAQ 285
P + W L L +T H G Y C A + G Q
Sbjct: 1432 TSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 1489
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 62.8 bits (151), Expect = 6e-10
Identities = 83/318 (26%), Positives = 125/318 (39%), Gaps = 42/318 (13%)
Query: 16 PAELFLIASPS--HPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
P + ++ SPS + G VTLTC++ S A + +D L + + L +
Sbjct: 238 PKGVKILLSPSGRNILPGELVTLTCQVN--SSYPAVSSIKWLKDGVRLQ---TKTGVLHL 292
Query: 74 AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLI 133
D G Y C+A+ ++ I++H + +A+V + P G ++E + L+
Sbjct: 293 PQAAWSDAGVYTCQAENGVGSLVSP---PISLH-IFMAEVQVS---PAGPILENQTVTLV 345
Query: 134 CSVAM-GTGDITFLWYKGAVGL-NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGP 191
C+ D+ + WYK V L + S T R A +D Y+C +N +G
Sbjct: 346 CNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLAT-------RADTGFYFCEVQNVHGS 398
Query: 192 SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGS 251
SG VS+ V P P+L QA + + LHC + P H L S
Sbjct: 399 ERSGPVSVVVNHPPLTPVLTAFL-ETQAGLVGI--LHCSVV-SEPLATLVLSHGGHILAS 454
Query: 252 RSAPSGGGASFN------------LSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTG 299
S S F+ L E SG Y C A N LG S TL+F
Sbjct: 455 TSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATS---TLDFHANAA 511
Query: 300 ARSNHLTSGVIEGLLSTL 317
+ V+EG TL
Sbjct: 512 RLLISPAAEVVEGQAVTL 529
Score = 56.6 bits (135), Expect = 4e-08
Identities = 71/291 (24%), Positives = 109/291 (37%), Gaps = 48/291 (16%)
Query: 22 IASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDT 81
IASP EG+ V C P++ C R G + + + E T
Sbjct: 144 IASPVELLEGTEVDFNCSTPYV---------CLQEQVRLQWQGQDPARSVTFNSQKFEPT 194
Query: 82 GSYWCEAQTMA------SKVLR------SRRSQINVH---RVPVADVSLETQPPGGQVME 126
G E MA ++LR + R+Q +H + V + P G ++
Sbjct: 195 GVGHLETLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILP 254
Query: 127 GDRLVLICSVAMGTGDITFL-WYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
G+ + L C V ++ + W K G+ LQ+K T +P SDA Y C A
Sbjct: 255 GELVTLTCQVNSSYPAVSSIKWLKD--GVRLQTK-----TGVLHLPQAAWSDAGVYTCQA 307
Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLR---APRAQAAVEDVLELHCEALRGSPPILYWF 242
ENG G V P+S I M +P + L C +P L +
Sbjct: 308 ENGVGS--------LVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYS 359
Query: 243 YHEDITLGSRSAPSGGGASFNLSL-TEEHSGNYSCEANNGLGAQRSEAVTL 292
++++ L + L L T +G Y CE N G++RS V++
Sbjct: 360 WYKNHVL----LEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSV 406
Score = 49.7 bits (117), Expect = 5e-06
Identities = 68/273 (24%), Positives = 105/273 (38%), Gaps = 48/273 (17%)
Query: 83 SYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGD 142
+Y C AQ + + R Q+ RV VA+ PG V EG L L C + G G
Sbjct: 1422 TYVCTAQNLLGSISTIGRLQVEGARV-VAE-------PGLDVPEGAALNLSCRLLGGPGP 1473
Query: 143 I---TFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSI 199
+ TF W+ L+ + + T V + A Y+C+AE G + S V +
Sbjct: 1474 VGNSTFAWFWNDRRLHAEPVPTLAFT------HVARAQAGMYHCLAELPTGAAASAPVML 1527
Query: 200 TVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGG 259
V P P +M+ + + +L+ + S P+ H L + S P G
Sbjct: 1528 RVLYPPKTPTMMVFV-EPEGGLRGILDCRVD----SEPLASLTLHLGSRLVASSQPQGAP 1582
Query: 260 ASFNL--------------SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHL 305
A ++ +L G Y C A+N LG S + + F V R +
Sbjct: 1583 AEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLG---SASTSTYFGVRALHRLHQF 1639
Query: 306 TS-----GVIEGLLSTLGPATVALLFCYGLKRK 333
G++ GLL L + L CY +R+
Sbjct: 1640 QQLLWVLGLLVGLLLLL----LGLGACYTWRRR 1668
Score = 46.6 bits (109), Expect = 4e-05
Identities = 57/245 (23%), Positives = 91/245 (37%), Gaps = 41/245 (16%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
++S KL++ + D+GSY CEA + S Q+ V V+ P ++
Sbjct: 856 ANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVS--------PSPELQ 907
Query: 126 EGDRLVLICSVAMGTGDIT-FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
EG +VL C V G + T + WY+ L Q S +A ++ + A Y+C
Sbjct: 908 EGQAVVLSCQVHTGVPEGTSYRWYRDGQPL------QESTSATLRFAAITLTQAGAYHCQ 961
Query: 185 AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV----LELHCEALRGSPPILY 240
A+ G + ++ P+S + + D L L + PP
Sbjct: 962 AQ------APGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQL 1015
Query: 241 WFYHED----ITLGSRSAPSGGGASFNLSLTE------------EHSGNYSCEANNGLGA 284
H D TL P G ++++ E G Y CEA+N LG
Sbjct: 1016 RLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQ 1075
Query: 285 QRSEA 289
+ A
Sbjct: 1076 ASASA 1080
Score = 46.6 bits (109), Expect = 4e-05
Identities = 73/304 (24%), Positives = 121/304 (39%), Gaps = 62/304 (20%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKED 80
++A + EG+P+T+TC P ++ A + ++ + R L G ++S +A +
Sbjct: 1264 ILAPEAAVPEGAPITVTCADP---AAHAPTLYTWYHNGRWLQEGPAASLSFLVAT--RAH 1318
Query: 81 TGSYWCEAQTMASKVLRSRRSQINVHRVP-----------------VADVSLETQPPGGQ 123
G+Y C+AQ A SR + + V P V +++++PP
Sbjct: 1319 AGAYSCQAQD-AQGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAVIQCTVDSEPPAEL 1377
Query: 124 VMEGDRLVL-----ICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
+ D VL + S+A GTG + + A+ L +Q ++P +
Sbjct: 1378 ALSHDGKVLATSSGVHSLASGTGHVQVA--RNALRLQVQ-----------DVP----AGD 1420
Query: 179 EQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
+ Y C A+N G S G + + V+ P L P A L L C L G P
Sbjct: 1421 DTYVCTAQNLLGSISTIGRLQVEGARVVAEP--GLDVPEGAA-----LNLSCRLLGGPGP 1473
Query: 238 I----LYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
+ WF++ D L + P+ +F + +G Y C A GA S V L
Sbjct: 1474 VGNSTFAWFWN-DRRLHAEPVPT---LAFT-HVARAQAGMYHCLAELPTGAAASAPVMLR 1528
Query: 294 FTVP 297
P
Sbjct: 1529 VLYP 1532
Score = 42.7 bits (99), Expect = 6e-04
Identities = 65/267 (24%), Positives = 104/267 (38%), Gaps = 29/267 (10%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
EG V LTC + + AQ + +++D G + + + + D SY C
Sbjct: 1099 EGQLVNLTCLV--WTTHPAQLTYTWYQD----GQQRLDAHSIPLPNVTVRDATSYRCGVG 1152
Query: 90 TMASKVLRSRRSQINVHRVPV-ADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWY 148
SR ++V P ++ + GGQ+ +++C+V L +
Sbjct: 1153 PPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLA-----LVLCTVDSRPPAQLALSH 1207
Query: 149 KGAVGLNLQSKTQRSL--TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
G + L S T S+ T E+ + D Y C A + G + + S+ +R+
Sbjct: 1208 AGRL---LASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANT---SLELRLEGV 1261
Query: 207 RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFN-LS 265
R IL AP A + + C P LY +YH R G AS + L
Sbjct: 1262 RVIL---APEAAVPEGAPITVTCADPAAHAPTLYTWYHN-----GRWLQEGPAASLSFLV 1313
Query: 266 LTEEHSGNYSCEANNGLGAQRSEAVTL 292
T H+G YSC+A + G + S L
Sbjct: 1314 ATRAHAGAYSCQAQDAQGTRSSRPAAL 1340
Score = 36.6 bits (83), Expect = 0.045
Identities = 75/305 (24%), Positives = 101/305 (33%), Gaps = 43/305 (14%)
Query: 17 AELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAM 76
A LI+ + EG VTL+C+ + DA+F + GPG S L + A
Sbjct: 510 AARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSS----LLLPAA 565
Query: 77 WKEDTGSYWCEAQTMASKVLRSRRSQINV---HRVPVADVSLETQPPGGQVMEGDRLVLI 133
D GSY C A+ S S + + V R P L+ G G R +L+
Sbjct: 566 SSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGA--GRRGLLL 623
Query: 134 CSVAMGTGDITFLWYKG-AVGLNLQS-----------------KTQRSLTAEYEIPSVRE 175
C V L +K V +L S K L E P + E
Sbjct: 624 CRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEE 683
Query: 176 SDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR-- 233
Y C A N G + S T + ++ AP L C R
Sbjct: 684 EGL--YLCEASNALG---NASTSATFN---GQATVLAIAPSHTLQEGTEANLTCNVSREA 735
Query: 234 -GSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
GSP WF + G A L + + Y+C GAQ S V L
Sbjct: 736 AGSPANFSWFRN-----GVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLL 790
Query: 293 NFTVP 297
+ P
Sbjct: 791 SVLYP 795
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 62.0 bits (149), Expect = 1e-09
Identities = 71/323 (21%), Positives = 131/323 (40%), Gaps = 33/323 (10%)
Query: 30 EGSPVTLTCKMPFLQSSDAQF-----QFCFFRDTRALGPGW-------SSSPKLQIAAMW 77
EG T++C++ S Q Q +FRD R L SS K+ + +
Sbjct: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
D G Y+C+ T + + + + R + D+ +T +EG+ + + C+
Sbjct: 116 ISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT------AVEGEEIEVNCTAM 169
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR-----SLTAEYEIPSVRESDAEQYYCVAENGYGPS 192
T W+KG L +S+ + ++T++ + +E D C E+ P+
Sbjct: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH---PA 226
Query: 193 PSGLVS----ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G + + V+ I M + D LEL CEA+ P++ + D
Sbjct: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
Query: 249 LGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSN--HLT 306
+ + SG N +L + +G Y CEA+N +G S+ + + G + +
Sbjct: 287 MPQHAVLSGPNLFIN-NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVD 345
Query: 307 SGVIEGLLSTLGPATVALLFCYG 329
VI G+++ + A + LL G
Sbjct: 346 HAVIGGVVAVVVFAMLCLLIILG 368
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 61.6 bits (148), Expect = 1e-09
Identities = 64/227 (28%), Positives = 95/227 (41%), Gaps = 17/227 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I K D G Y CE + A + + + ++ P LE + GD +
Sbjct: 6043 LEILNSTKRDAGQYSCEIENEAGRDVCG--ALVSTLEPPYFVTELEPL----EAAVGDSV 6096
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYCVAEN 187
L C VA GT +IT WYKG L + + T A V +D+ +Y C AEN
Sbjct: 6097 SLQCQVA-GTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAEN 6155
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + S V ++ P + + V + L C L GS PI +Y + +
Sbjct: 6156 SIGTASSKTV-FRIQERQLPPSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGV 6213
Query: 248 TLGS----RSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEA 289
L +++ A+ + T+ HSG YSC A+N LG S A
Sbjct: 6214 LLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA 6260
Score = 56.6 bits (135), Expect = 4e-08
Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 30/278 (10%)
Query: 32 SPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDTGSY 84
S V TC++ + + +F+D + + + L+I + D G++
Sbjct: 4124 SVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNF 4183
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A + + V P S T+P V+ G V + S G+ +T
Sbjct: 4184 TCRATNSVGS--KDSSGALIVQEPP----SFVTKPGSKDVLPGSA-VCLKSTFQGSTPLT 4236
Query: 145 FLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITV 201
W+KG L T+ +L + E+ V+ SD+ Y C N +G V +
Sbjct: 4237 IRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSN-----VAGGVECSA 4291
Query: 202 RIPVSRPILMLR--APRAQAAVEDVLELHCEALRGSPPI-LYWFYHE-DITLGSRSAPSG 257
+ V P + P D +L C+ + G+PPI + WF ++ +I S+ S
Sbjct: 4292 NLFVKEPATFVEKLEPSQLLKKGDATQLACK-VTGTPPIKITWFANDREIKESSKHRMSF 4350
Query: 258 GGASFNLSLTE---EHSGNYSCEANNGLGAQRSEAVTL 292
++ L LT+ E SG Y CEA N G+ ++ +
Sbjct: 4351 VESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 4388
Score = 54.7 bits (130), Expect = 2e-07
Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 21/229 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + ED G Y C + + K S +QI + P LE +V GD
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGK--DSCSAQILILEPPYFVKQLEPV----KVSVGDSA 7978
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCVAEN 187
L C +A GT +I WYKG L + + R+ A V +D+ +Y C AEN
Sbjct: 7979 SLQCQLA-GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 8037
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G S +TV+ P + Q V + C A+ GS PI +Y +
Sbjct: 8038 SVG-EVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGK 8095
Query: 248 TLGSRSAPS------GGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEA 289
L + +P+ A+ N+ T+ +G YSC A N +G+ S A
Sbjct: 8096 PL--KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSA 8142
Score = 52.8 bits (125), Expect = 6e-07
Identities = 72/283 (25%), Positives = 108/283 (38%), Gaps = 34/283 (12%)
Query: 29 TEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-------LQIAAMWKEDT 81
T G PVTLTC++ + A Q C++RD L + L+I +
Sbjct: 6187 TVGLPVTLTCRL----NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHS 6242
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G Y C A S R R P + +P V+ G+ C V G
Sbjct: 6243 GQYSCSASNPLGTASSSARLTA---REPKKSPFFDIKPVSIDVIAGESADFECHVT-GAQ 6298
Query: 142 DITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
+ W K + T T I V + D+ QY C A N G
Sbjct: 6299 PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD-----M 6353
Query: 199 ITVRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPI-LYWF-----YHEDITLG 250
+ ++ V P ++ A + + ++L C+ + GSP I + WF HE
Sbjct: 6354 CSAQLSVKEPPKFVKKLEASKVAKQGESIQLECK-ISGSPEIKVSWFRNDSELHESWKYN 6412
Query: 251 SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
S + N + E+ SG+Y CEA+NG+G A S A+T+
Sbjct: 6413 MSFINSVALLTINEASAED-SGDYICEAHNGVGDASCSTALTV 6454
Score = 51.6 bits (122), Expect = 1e-06
Identities = 64/292 (21%), Positives = 113/292 (38%), Gaps = 44/292 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
EPA + A P T G TL CK+ + + +++D + L ++
Sbjct: 5702 EPAVIVEKAGPMTVTVGETCTLECKV----AGTPELSVEWYKDGKLLTSSQKHKFSFYNK 5757
Query: 68 SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
L+I ++ ++D G+Y + Q K + ++ VP + + GG + G
Sbjct: 5758 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP-PSFTRRLKNTGGVL--G 5814
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYCV 184
+L C VA G+ I+ W+ + +K Q + + ++ S+ SD Y CV
Sbjct: 5815 ASCILECKVA-GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 5873
Query: 185 AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWFY 243
A N G V + V P ++ P + +RG+PP + WF
Sbjct: 5874 AANVAGSDECRAV-----LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWF- 5927
Query: 244 HEDITLGSRSAPSGGGAS------------FNLSLTEEHSGNYSCEANNGLG 283
G+R G + FN+ +++ SG Y+C +N G
Sbjct: 5928 -----RGARELVKGDRCNIYFEDTVAELELFNIDISQ--SGEYTCVVSNNAG 5972
Score = 51.2 bits (121), Expect = 2e-06
Identities = 67/264 (25%), Positives = 111/264 (42%), Gaps = 43/264 (16%)
Query: 50 FQFCFFRDTRALGPGWSSS-------PKLQIAAMWKEDTGSYWCEAQTMASKV-----LR 97
F+ +F+ +R L PG S + +L++ + ++G Y C A L
Sbjct: 6863 FKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 6922
Query: 98 SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ 157
+ V R+ AD S+ET P +++ + GT I+ W K ++
Sbjct: 6923 VKEPATFVKRL--ADFSVETGSP----------IVLEATYTGTPPISVSWIKDEYLISQS 6970
Query: 158 SKTQRSLTAEYEIPSVRESDAE---QYYCVAENGYGPSP-SGLVSITVRIPVSRPILMLR 213
+ ++T + I + ES E QY C+ EN G LVS+ + P +
Sbjct: 6971 ERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV-----LEPPYFIEP 7025
Query: 214 APRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPS------GGGASFNLSLT 267
+A + + L C+ + G+P I +Y E L RSAP+ AS ++
Sbjct: 7026 LEHVEAVIGEPATLQCK-VDGTPEIRISWYKEHTKL--RSAPAYKMQFKNNVASLVINKV 7082
Query: 268 EEHS-GNYSCEANNGLGAQRSEAV 290
+ G YSC+A+N +GA S AV
Sbjct: 7083 DHSDVGEYSCKADNSVGAVASSAV 7106
Score = 50.1 bits (118), Expect = 4e-06
Identities = 62/276 (22%), Positives = 102/276 (36%), Gaps = 30/276 (10%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW-------SSSPKLQIAAMWKEDTG 82
+G + L CK+ S + + +FR+ L W +S L I ED+G
Sbjct: 6378 QGESIQLECKI----SGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 6433
Query: 83 SYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGD 142
Y CEA S + + V PV +P ++G ++L C ++ GT
Sbjct: 6434 DYICEAHNGVGDA--SCSTALTVKAPPV----FTQKPSPVGALKGSDVILQCEIS-GTPP 6486
Query: 143 ITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSI 199
+W K + K T + I ++ SD +Y+C A N G S + S+
Sbjct: 6487 FEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG-SDTCSCSV 6545
Query: 200 TVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITL----GSRSAP 255
+ P P + + + D +EL P + W + +R +
Sbjct: 6546 KFKEP---PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF 6602
Query: 256 SGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAV 290
A+ L E +SG Y C+ N G + AV
Sbjct: 6603 IDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAV 6638
Score = 49.7 bits (117), Expect = 5e-06
Identities = 61/294 (20%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQ-- 72
EPA++ A TE P+TL C + + + + + +D + + P S +
Sbjct: 5139 EPAQIVEKAKSVDVTEKDPMTLECVV----AGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194
Query: 73 -----IAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
I ++ K+D+G Y + + ++ +P + T+ + G
Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKM---DKVLG 5251
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCV 184
+ + C V+ G+ I+ W+K ++ +K + + E+ ++ D Y C
Sbjct: 5252 SSIHMECKVS-GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCK 5310
Query: 185 AENGYGPSP-SGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
N G SG+ +TV+ P P +++ R QA + +E L+G+PP ++
Sbjct: 5311 VSNVAGDDACSGI--LTVKEP---PSFLVKPGRQQAIPDSTVEFKA-ILKGTPPFKIKWF 5364
Query: 244 HEDITLGSRS----APSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTL 292
+D+ L S G + NL S+ +G Y+C N +G+ + L
Sbjct: 5365 KDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 5418
Score = 49.7 bits (117), Expect = 5e-06
Identities = 67/291 (23%), Positives = 102/291 (35%), Gaps = 57/291 (19%)
Query: 27 HPTEGSPVTLTCKMP-------------FLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
H T G PV C++ L DA Q F + L QI
Sbjct: 7126 HETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL----------QI 7175
Query: 74 AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLI 133
+ G Y C A S + ++ H VP + +P + G+
Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPF---FDLKPVSVDLALGESGTFK 7232
Query: 134 CSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAENGYG 190
C V GT I W K + + +L TA + V + DA QY C A N G
Sbjct: 7233 CHVT-GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAG 7291
Query: 191 PSPSGLVSITVRIPVSRPILMLRA--PRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
S + ++ V P ++ P ++ C+ + GSP I +Y ++
Sbjct: 7292 KD-----SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECK-IGGSPEIKVLWYKDETE 7345
Query: 249 LGSRSAPSGGGASFNLS------------LTEEHSGNYSCEANNGLGAQRS 287
+ S F +S L+ E SG+Y+CEA+N G+ S
Sbjct: 7346 IQESS-------KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASS 7389
Score = 48.5 bits (114), Expect = 1e-05
Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 33/292 (11%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
EP P G VT T + F+ +FR R L G +
Sbjct: 5891 EPPSFVKEPEPLEVLPGKNVTFTSVI----RGTPPFKVNWFRGARELVKGDRCNIYFEDT 5946
Query: 68 SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
+L++ + +G Y C A + + R + + +S + PG
Sbjct: 5947 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPG------ 6000
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCV 184
+ +++ S GT I+ W K + K T + EI + + DA QY C
Sbjct: 6001 -KSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCE 6059
Query: 185 AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
EN G G + T+ P + +AAV D + L C+ + G+P I +Y
Sbjct: 6060 IENEAGRDVCGALVSTLE----PPYFVTELEPLEAAVGDSVSLQCQ-VAGTPEITVSWYK 6114
Query: 245 EDITLGS----RSAPSGGGAS--FNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
D L R+ + A+ FN + SG Y+C+A N +G S+ V
Sbjct: 6115 GDTKLRPTPEYRTYFTNNVATLVFN-KVNINDSGEYTCKAENSIGTASSKTV 6165
Score = 48.1 bits (113), Expect = 1e-05
Identities = 71/296 (23%), Positives = 109/296 (36%), Gaps = 46/296 (15%)
Query: 15 EPAELFLIASPSH-PTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WS 66
EP PS+ G L CK+ Q +F++ + L +
Sbjct: 3735 EPPSFVKKVDPSYLMLPGESARLHCKL----KGSPVIQVTWFKNNKELSESNTVRMYFVN 3790
Query: 67 SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
S L I + ED+GSY CEA S ++I + P +LE ++
Sbjct: 3791 SEAILDITDVKVEDSGSYSCEAVNDVGS--DSCSTEIVIKEPPSFIKTLEP----ADIVR 3844
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK----TQRSLTAEYEIPSVRESDAEQYY 182
G +L C V+ GTG W+K + K +Q+SL EI S +D +Y
Sbjct: 3845 GTNALLQCEVS-GTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYE 3902
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCE------ALRGSP 236
CV N G + L+ P V+D++ L + A+RGS
Sbjct: 3903 CVVANEVG-----------KCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSE 3951
Query: 237 PI-LYWFYHEDITLG----SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
PI + W +++ S +G + G Y+C A N G+Q S
Sbjct: 3952 PISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTS 4007
Score = 47.8 bits (112), Expect = 2e-05
Identities = 70/268 (26%), Positives = 110/268 (41%), Gaps = 26/268 (9%)
Query: 67 SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
S+ L++ + ED+G Y CEAQ A S S + V P + E +P +V++
Sbjct: 4353 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS--SIVIVKESPY--FTKEFKPI--EVLK 4406
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYC 183
++L+ VA GT W+K L K + + +I +DA +Y C
Sbjct: 4407 EYDVMLLAEVA-GTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQC 4465
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWF 242
N G S + R+ + P ++ + +++ L+GS PI + W
Sbjct: 4466 RVTNEVGSS-----ICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWL 4520
Query: 243 YHED-ITLGS--RSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPT 298
D IT R AS LS E +H G Y C+A N G QR A+ L+ P
Sbjct: 4521 KDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSAL-LSVKEPA 4579
Query: 299 GARSNHLTSGVIEGLLSTLGPATVALLF 326
++ V +G PAT+ + F
Sbjct: 4580 TITEEAVSIDVTQG-----DPATLQVKF 4602
Score = 47.0 bits (110), Expect = 3e-05
Identities = 52/227 (22%), Positives = 97/227 (42%), Gaps = 17/227 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ + + + G Y C+ + A ++ + ++V + ++ +P +V GD
Sbjct: 7550 LQFSRVEPANAGKYTCQIKNDAG--MQECFATLSV----LEPATIVEKPESIKVTTGDTC 7603
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAEN 187
L C+VA GT +++ W+K L +K + S + +I +V SD+ Y +N
Sbjct: 7604 TLECTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQN 7662
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G S S+ V P + + + C+ GSPPI ++HE
Sbjct: 7663 PVGKD-SCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFHEGN 7720
Query: 248 TLGS----RSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEA 289
+ S ++ + + +++ EE SG+Y+C A N G+ A
Sbjct: 7721 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA 7767
Score = 46.6 bits (109), Expect = 4e-05
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 20/196 (10%)
Query: 112 DVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYE-- 169
DV + + QV+E R V+ V D+ WYK + +N Q + + E
Sbjct: 3146 DVRIRSIKKEVQVIEKQRAVVEFEV--NEDDVDAHWYKDGIEINFQVQERHKYVVERRIH 3203
Query: 170 ---IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE 226
I R+SDA +Y VA S+T+ + P +L+ +
Sbjct: 3204 RMFISETRQSDAGEYTFVAGRNRS-------SVTLYVNAPEPPQVLQELQPVTVQSGKPA 3256
Query: 227 LHCEALRGSP-PILYWFYHED-ITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNG 281
C + G P P + W+ E ++ G + G + L L E E + Y+CEA N
Sbjct: 3257 RFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKND 3316
Query: 282 LGAQRSEAVTLNFTVP 297
G + A +L+ VP
Sbjct: 3317 YGVATTSA-SLSVEVP 3331
Score = 46.6 bits (109), Expect = 4e-05
Identities = 56/231 (24%), Positives = 96/231 (41%), Gaps = 13/231 (5%)
Query: 67 SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
+S L + + K D+G Y C A K S +Q+N+ + + + E
Sbjct: 8206 NSAHLTVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVEETE 8263
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYC 183
G+ L VA G+ IT WYK + + S T ++ T ++ +DA Y C
Sbjct: 8264 GNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 8322
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWF 242
N G S SI ++ P P+ + + ++L C ++GS PI + W
Sbjct: 8323 KVSNDAG-SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCH-VQGSEPIRIQWL 8380
Query: 243 YH-EDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLGAQRSEA 289
+I R + S + L L + SG+Y C+A+N G+ +++
Sbjct: 8381 KAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKS 8431
Score = 46.2 bits (108), Expect = 6e-05
Identities = 73/295 (24%), Positives = 107/295 (36%), Gaps = 43/295 (14%)
Query: 11 APLC--EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG---- 64
APL EP P G+ VT T + F +F+ + L PG
Sbjct: 7767 APLTVREPPSFVQKPDPMDVLTGTNVTFTS----IVKGTPPFSVSWFKGSSELVPGDRCN 7822
Query: 65 ---WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVA---DVSLETQ 118
S +L++ + +G Y C A K + I V D S+E
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKG 7882
Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRE 175
P ++EG GT I+ W K + + + T +A EIPS
Sbjct: 7883 KP--LILEG--------TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTV 7932
Query: 176 SDAEQYYCVAENGYGPSPSGLVSITVRIPV-SRPILMLRAPRAQAAVEDVLELHCEALRG 234
DA QY C EN SG S + +I + P + + + +V D L C+ L G
Sbjct: 7933 EDAGQYNCYIENA-----SGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQ-LAG 7986
Query: 235 SPPILYWFYHEDITLGSRSA------PSGGGASFNLSLTEEHSGNYSCEANNGLG 283
+P I +Y D L + + FN + SG Y C+A N +G
Sbjct: 7987 TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFN-QVDINDSGEYICKAENSVG 8040
Score = 45.8 bits (107), Expect = 7e-05
Identities = 55/229 (24%), Positives = 85/229 (37%), Gaps = 20/229 (8%)
Query: 72 QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
QI+ E++G+Y CEA+ A S ++ V P L+ +V++ +
Sbjct: 4920 QISGARVENSGTYVCEARNDAGTA--SCSIELKVKEPPTFIRELKPV----EVVKYSDVE 4973
Query: 132 LICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C V GT W K + K T R I SD +Y C+ N
Sbjct: 4974 LECEVT-GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN- 5031
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
G S + R+ + P ++ V + GSPPI + +D
Sbjct: 5032 ----EGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 5087
Query: 249 LGSRS----APSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTL 292
L + A+ + S+ HSG Y+C+A N G +R A L
Sbjct: 5088 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 5136
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/271 (25%), Positives = 104/271 (38%), Gaps = 34/271 (12%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDTGS 83
GS + + CK+ AQ+ F+D + + S L++ + EDT +
Sbjct: 5251 GSSIHMECKVSGSLPISAQW----FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 5306
Query: 84 YWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDI 143
Y C+ +A S + V P V PG Q D V ++ GT
Sbjct: 5307 YTCKVSNVAGDDACS--GILTVKEPPSFLVK-----PGRQQAIPDSTVEFKAILKGTPPF 5359
Query: 144 TFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
W+K V L K L T+ + SV S QY C N G S T
Sbjct: 5360 KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSD-----SCT 5414
Query: 201 VRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPI-LYWFYHEDITLGS---RSA 254
+ V+ P ++ A V+ D L C+ + GSP I + WF +E S R
Sbjct: 5415 TMLLVTEPPKFVKKLEASKIVKAGDSSRLECK-IAGSPEIRVVWFRNEHELPASDKYRMT 5473
Query: 255 PSGGGASFNLS-LTEEHSGNYSCEANNGLGA 284
A ++ L+ E SG++ CEA N G+
Sbjct: 5474 FIDSVAVIQMNNLSTEDSGDFICEAQNPAGS 5504
Score = 44.3 bits (103), Expect = 2e-04
Identities = 52/235 (22%), Positives = 92/235 (39%), Gaps = 20/235 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
+Q+ + ED+G + CEAQ A S +++ V PV + PP + ++ +
Sbjct: 5481 IQMNNLSTEDSGDFICEAQNPAGST--SCSTKVIVKEPPV----FSSFPPIVETLKNAEV 5534
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C ++ GT +WYK L K ++ I +V SD +Y+C A+N
Sbjct: 5535 SLECELS-GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G S + + ++ ++ P P + + + EL P + W ++
Sbjct: 5594 EVG-SDTCVCTVKLKEP---PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649
Query: 248 TL----GSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
+ R A+ + E ++G Y C+ N G R TL P
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND-GGMRENMATLMVLEP 5703
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/228 (24%), Positives = 84/228 (36%), Gaps = 17/228 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ-VMEGDR 129
LQ A + G Y C+ + + N+ + V + ++ + G V G+
Sbjct: 5668 LQFAKAEPANAGKYICQIKNDGGM-------RENMATLMVLEPAVIVEKAGPMTVTVGET 5720
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAE 186
L C VA GT +++ WYK L K + S + I SV DA Y +
Sbjct: 5721 CTLECKVA-GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQ 5779
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
N G S V + V P R + L C+ SP + WF+ +
Sbjct: 5780 NNVGKSSCTAV-VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKT 5838
Query: 247 -ITLGSRSAPSGGGASFNL---SLTEEHSGNYSCEANNGLGAQRSEAV 290
I G++ + L SL GNY+C A N G+ AV
Sbjct: 5839 KIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886
Score = 44.3 bits (103), Expect = 2e-04
Identities = 66/289 (22%), Positives = 107/289 (37%), Gaps = 26/289 (8%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKM---PFLQSSDAQFQFCFFRDTRALGPGWSSSPKL 71
EPA + GSP+ L P + S + ++ + R S L
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 6984
Query: 72 QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
+I ED Y C + A + + + ++V P LE + + G+
Sbjct: 6985 EILESTIEDYAQYSCLIENEAGQDICE--ALVSVLEPPYFIEPLEHV----EAVIGEPAT 7038
Query: 132 LICSVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
L C V GT +I WYK A +Q K A I V SD +Y C A
Sbjct: 7039 LQCKVD-GTPEIRISWYKEHTKLRSAPAYKMQFKNN---VASLVINKVDHSDVGEYSCKA 7094
Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHE 245
+N G S V + ++ P + + + C + GS P+ +Y +
Sbjct: 7095 DNSVGAVASSAV-LVIKARKLPPFFARKLKDVHETLGFPVAFECR-INGSEPLQVSWYKD 7152
Query: 246 DITLGS----RSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEA 289
+ L +++ A+ + T++ H G Y+C A+N LG S A
Sbjct: 7153 GVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 7201
Score = 43.5 bits (101), Expect = 4e-04
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 21/130 (16%)
Query: 166 AEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP------VSRPILMLRAPRAQA 219
A EIP + D+ Y C A N G S S ++TVR P V LML A+
Sbjct: 3699 ATLEIPLAKLKDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESAR- 3756
Query: 220 AVEDVLELHCEALRGSPPI-LYWFYH-EDITLGSRSAPSGGGASFNLSLTE---EHSGNY 274
LHC+ L+GSP I + WF + ++++ + + L +T+ E SG+Y
Sbjct: 3757 -------LHCK-LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSY 3808
Query: 275 SCEANNGLGA 284
SCEA N +G+
Sbjct: 3809 SCEAVNDVGS 3818
Score = 42.4 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 20/227 (8%)
Query: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
ED+G Y CEA A S + + V P+ +P + ++G + L C +
Sbjct: 7371 EDSGDYTCEAHNAAGSA--SSSTSLKVKEPPI----FRKKPHPIETLKGADVHLECEL-Q 7423
Query: 139 GTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
GT WYK L K + I +V +D +Y C A N G S +
Sbjct: 7424 GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG-SDTC 7482
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHE-DITLGSRS- 253
+ SI ++ P P + + V ++L P + WF + +I S +
Sbjct: 7483 VGSIALKAP---PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNI 7539
Query: 254 --APSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
+ S A+ S E ++G Y+C+ N G Q A TL+ P
Sbjct: 7540 WISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA-TLSVLEP 7585
Score = 42.0 bits (97), Expect = 0.001
Identities = 70/298 (23%), Positives = 105/298 (35%), Gaps = 54/298 (18%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
EPA + P T G+P L C + A+ +F+D R L +
Sbjct: 6643 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAK----WFKDGRELSADSKHHITFINK 6698
Query: 68 SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG------ 121
L+I D G Y E + K ++VH VS PP
Sbjct: 6699 VASLKIPCAEMSDKGLYSFEVKNSVGK----SNCTVSVH------VSDRIVPPSFIRKLK 6748
Query: 122 -GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESD 177
+ G +VL C V+ G+ I+ W++ + K Q S + + + SD
Sbjct: 6749 DVNAILGASVVLECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSD 6807
Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
Y CVA N G V + V P + P + + + +RG+PP
Sbjct: 6808 TGIYTCVAANVAGSDECSAV-----LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPP 6862
Query: 238 I-LYWFYHEDITLGSRSAPSGGGASFNLS--LTE--------EHSGNYSCEANNGLGA 284
+ WF GSR G + +L +TE SG+YSC N G+
Sbjct: 6863 FKVKWF------KGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGS 6914
Score = 39.7 bits (91), Expect = 0.005
Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 9/167 (5%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQ 180
V +GD L + GT +IT W+K L L SK + S+T + +I S + D+ +
Sbjct: 4590 VTQGDPATLQVKFS-GTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGE 4648
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Y +N G S S I V + P + + + ++L C P +
Sbjct: 4649 YTFEVQNDVGRS-SCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707
Query: 241 WFY-HEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG 283
WF ++I+ + S + L +++ SG Y+C A N G
Sbjct: 4708 WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 4754
Score = 37.7 bits (86), Expect = 0.020
Identities = 46/177 (25%), Positives = 67/177 (37%), Gaps = 9/177 (5%)
Query: 123 QVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAE 179
QV GD L +VA GT ++ WYK L K + S A+ + S D+
Sbjct: 4027 QVTAGDPATLEYTVA-GTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 4085
Query: 180 QYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPIL 239
QY N G S S + TV P + V L C+ P +
Sbjct: 4086 QYTFEISNEVGSS-SCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRV 4144
Query: 240 YWFYHEDITLGS---RSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVTL 292
WF S R A G AS + + + +GN++C A N +G++ S +
Sbjct: 4145 SWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 4201
Score = 36.2 bits (82), Expect = 0.059
Identities = 57/294 (19%), Positives = 107/294 (36%), Gaps = 47/294 (15%)
Query: 29 TEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDT 81
+EG P C++ S + ++ + + P + + +L+IA + ED
Sbjct: 3357 SEGQPARFQCRV-----SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3411
Query: 82 GSYWCEAQTMASKV-------LRSRRSQINVHRVPVADVSLETQPPGGQVME------GD 128
G+Y A +V L + S ++ ++ ++ P + +E G
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGH 3471
Query: 129 RLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCVA 185
C + ++ F W+K + K + EI + D +Y C A
Sbjct: 3472 LAKFTCEI-QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 3530
Query: 186 ENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
N YG S + +++T P P + R V + C P++ +
Sbjct: 3531 SNEYGSVSCTATLTVTEAYP---PTFLSRPKSLTTFVGKAAKFICTVT--GTPVIETIWQ 3585
Query: 245 EDITLGSRSAPSGGGASFNL---------SLTEEHSGNYSCEANNGLGAQRSEA 289
+D G+ +PS + +LT + G YSC+A+N GA +A
Sbjct: 3586 KD---GAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQA 3636
Score = 35.0 bits (79), Expect = 0.13
Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 11/125 (8%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM-----EGDRLVL 132
K+D A+ +RS++ ++V +V VA S+E P GQ+M EG +
Sbjct: 31531 KKDLNMVVSAARISCGGAIRSQKG-VSVAKVKVA--SIEIGPVSGQIMHAVGEEGGHVKY 31587
Query: 133 ICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGY 189
+C + WY G L K T A + + + D Y C N Y
Sbjct: 31588 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 31647
Query: 190 GPSPS 194
G S
Sbjct: 31648 GEDSS 31652
Score = 32.3 bits (72), Expect = 0.85
Identities = 66/317 (20%), Positives = 107/317 (33%), Gaps = 50/317 (15%)
Query: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
L + AP EP ++ P G P + S Q + ++++ + L G+
Sbjct: 3231 LYVNAP--EPPQVLQELQPVTVQSGKPARFCAVI----SGRPQPKISWYKEEQLLSTGFK 3284
Query: 67 -------SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
L + + ED Y CEA+ S + V V D + P
Sbjct: 3285 CKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3344
Query: 120 PG-------GQVMEGDRLVLICSVAMGTGDITFLWY---KGAVGLNLQSKTQRSLTAEYE 169
P EG C V+ GT D+ WY K TQ T + E
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVS-GT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLE 3402
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS----------------RPILMLR 213
I D Y VA N G S ++++ P S P++ +
Sbjct: 3403 IAEAYPEDEGTYTFVASNAVG-QVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRK 3461
Query: 214 APRAQAAVEDVLELHCEALRGSPPILY-WF-----YHEDITLGSRSAPSGGGASFNLSLT 267
+ A+ + + CE ++ +P + + WF +E RS+ L
Sbjct: 3462 IEPLEVALGHLAKFTCE-IQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI-LRTQ 3519
Query: 268 EEHSGNYSCEANNGLGA 284
G Y+C+A+N G+
Sbjct: 3520 VVDCGEYTCKASNEYGS 3536
Score = 32.0 bits (71), Expect = 1.1
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%)
Query: 166 AEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVL 225
A+ IP+V ++++ +Y A NG G + S + V+ + P + R +
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATS-TAELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 226 ELHCEALRGSPPILYWFYHEDITLGSR--SAPSGGGASFNLSLTE---EHSGNYSCEANN 280
L + G P + FY + + S S G ++L + E E SG YS A N
Sbjct: 122 RLQVR-VTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 281 GLGAQRSEAVTL 292
+G S A L
Sbjct: 181 SVGRATSTAELL 192
Score = 30.4 bits (67), Expect = 3.2
Identities = 41/163 (25%), Positives = 61/163 (37%), Gaps = 24/163 (14%)
Query: 8 LICAPLCEPAELFLIASPSHPTEGSPVTL----TCKMPFLQSSDAQFQFCFFRDTRALGP 63
L+C P A+L +I P+ VTL TC M Q S + +FR+ R L P
Sbjct: 8729 LVCGPHIASAKLTVI-EPAWERHLQDVTLKEGQTCTMT-CQFSVPNVKSEWFRNGRILKP 8786
Query: 64 GWSSSP-------KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLE 116
KL IA + ED G Y C+ + + + +++ + P +
Sbjct: 8787 QGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETS------AELRIEAEP---IQFT 8837
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK 159
+ V E C V+ +T WYKG L K
Sbjct: 8838 KRIQNIVVSEHQSATFECEVSFDDAIVT--WYKGPTELTESQK 8878
Score = 30.0 bits (66), Expect = 4.2
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 18/146 (12%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLE--------- 116
S + L++ + K D+G Y C+A +A + +S++ + P + +
Sbjct: 8398 SGTAVLELRDVAKADSGDYVCKASNVAGS--DTTKSKVTIKDKPAVAPATKKAAVDGRLF 8455
Query: 117 --TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGA-VGLNLQSKT---QRSLTAEYEI 170
++P +V+E I V G W KG LN + Q+ A+ EI
Sbjct: 8456 FVSEPQSIRVVEKTTATFIAKVG-GDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 8514
Query: 171 PSVRESDAEQYYCVAENGYGPSPSGL 196
++D+ Y CVA N +G S +
Sbjct: 8515 RDTTKTDSGLYRCVAFNEHGEIESNV 8540
Score = 28.9 bits (63), Expect = 9.4
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSV 173
T+P V EG+ C G T W + L+ ++ Q + T + +EI SV
Sbjct: 32565 TKPRSMTVYEGESARFSCDTD-GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSV 32623
Query: 174 RESDAEQYYCVAENGYG 190
+ SD Y V EN G
Sbjct: 32624 QASDEGNYSVVVENSEG 32640
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 61.6 bits (148), Expect = 1e-09
Identities = 65/290 (22%), Positives = 118/290 (40%), Gaps = 31/290 (10%)
Query: 30 EGSPVTLTCKMPFLQSSDAQF-----QFCFFRDTRALGPGW-------SSSPKLQIAAMW 77
EG T++C++ S Q Q +FRD R L SS K+ + +
Sbjct: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
D G Y+C+ T + + + + R + D+ +T +EG+ + + C+
Sbjct: 116 ISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT------AVEGEEIEVNCTAM 169
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR-----SLTAEYEIPSVRESDAEQYYCVAENGYGPS 192
T W+KG L +S+ + ++T++ + +E D C E+ P+
Sbjct: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH---PA 226
Query: 193 PSGLVS----ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G + + V+ I M + D LEL CEA+ P++ + D
Sbjct: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
Query: 249 LGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPT 298
+ + SG N +L + +G Y CEA+N +G S+ + + PT
Sbjct: 287 MPQHAVLSGPNLFIN-NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
[Homo sapiens]
Length = 1070
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 15/237 (6%)
Query: 62 GPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
G + +L +A + + D G Y C A +A + RR +N+ V S +P
Sbjct: 367 GRVYQKGHELVLANIAESDAGVYTCHAANLAGQ----RRQDVNITVATVP--SWLKKPQD 420
Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Q+ EG L C + T T +WY+ + ++ S+ + I SV D Y
Sbjct: 421 SQLEEGKPGYLDC-LTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWY 479
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPIL 239
C++ +P+G + R+ V + P+ Q +E E + C A P +
Sbjct: 480 RCMSS-----TPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTI 534
Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
W + +L + G F +T + +GNY+C A+NG Q V L V
Sbjct: 535 KWERADGSSLPEWVTDNAGTLHF-ARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAV 590
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/183 (20%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
Query: 79 EDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+D+G++ C A+ + + RS + N+ + V L+ ++ ++ L C +
Sbjct: 94 QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ---YYCVAENGYGPSPS 194
G T+ W++ L+ ++ +++++ ++R + E Y C A + +G + S
Sbjct: 154 -GHPRPTYQWFRDGTPLS-DGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 195 GLVSITVRIPVSRPILMLRAPR--AQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
+ T+ I ++ AP+ A E+ + HC+ PP L W + ++ + +R
Sbjct: 212 SQ-NFTLSIADESFARVVLAPQDVVVARYEEAM-FHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 253 SAP 255
S P
Sbjct: 270 SRP 272
Score = 35.4 bits (80), Expect = 0.10
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 12/193 (6%)
Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWY-KGAVGLNLQSKTQRSLTAEYEIPSVRES 176
QP ++G R +L C V G + W GA + + + + + + R
Sbjct: 37 QPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD-RLQ 94
Query: 177 DAEQYYCVAENGYG--PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEAL 232
D+ + CVA + + S S ++ + P++ L+ P ++A ++ + L C
Sbjct: 95 DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV-LKHPASEAEIQPQTQVTLRCHID 153
Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG-AQRSE 288
P WF +S + NL+L EHSG YSC A++ G A S+
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213
Query: 289 AVTLNFTVPTGAR 301
TL+ + AR
Sbjct: 214 NFTLSIADESFAR 226
Score = 32.7 bits (73), Expect = 0.65
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 5/130 (3%)
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
+ VR +A Y C+ + GP ++ T+ + + + A E+ + C
Sbjct: 288 LTQVRPRNAGIYRCIGQGQRGPPI--ILEATLHLAEIEDMPLFEPRVFTAGSEE--RVTC 343
Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS-LTEEHSGNYSCEANNGLGAQRSE 288
+G P W+ H + L + G L+ + E +G Y+C A N G +R +
Sbjct: 344 LPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQD 403
Query: 289 AVTLNFTVPT 298
TVP+
Sbjct: 404 VNITVATVPS 413
>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor
[Homo sapiens]
Length = 1014
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 15/237 (6%)
Query: 62 GPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
G + +L +A + + D G Y C A +A + RR +N+ V S +P
Sbjct: 367 GRVYQKGHELVLANIAESDAGVYTCHAANLAGQ----RRQDVNITVATVP--SWLKKPQD 420
Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Q+ EG L C + T T +WY+ + ++ S+ + I SV D Y
Sbjct: 421 SQLEEGKPGYLDC-LTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWY 479
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPIL 239
C++ +P+G + R+ V + P+ Q +E E + C A P +
Sbjct: 480 RCMSS-----TPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTI 534
Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
W + +L + G F +T + +GNY+C A+NG Q V L V
Sbjct: 535 KWERADGSSLPEWVTDNAGTLHF-ARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAV 590
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/183 (20%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
Query: 79 EDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+D+G++ C A+ + + RS + N+ + V L+ ++ ++ L C +
Sbjct: 94 QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ---YYCVAENGYGPSPS 194
G T+ W++ L+ ++ +++++ ++R + E Y C A + +G + S
Sbjct: 154 -GHPRPTYQWFRDGTPLS-DGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 195 GLVSITVRIPVSRPILMLRAPR--AQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
+ T+ I ++ AP+ A E+ + HC+ PP L W + ++ + +R
Sbjct: 212 SQ-NFTLSIADESFARVVLAPQDVVVARYEEAM-FHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 253 SAP 255
S P
Sbjct: 270 SRP 272
Score = 35.4 bits (80), Expect = 0.10
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 12/193 (6%)
Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWY-KGAVGLNLQSKTQRSLTAEYEIPSVRES 176
QP ++G R +L C V G + W GA + + + + + + R
Sbjct: 37 QPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD-RLQ 94
Query: 177 DAEQYYCVAENGYG--PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEAL 232
D+ + CVA + + S S ++ + P++ L+ P ++A ++ + L C
Sbjct: 95 DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV-LKHPASEAEIQPQTQVTLRCHID 153
Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG-AQRSE 288
P WF +S + NL+L EHSG YSC A++ G A S+
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213
Query: 289 AVTLNFTVPTGAR 301
TL+ + AR
Sbjct: 214 NFTLSIADESFAR 226
Score = 32.7 bits (73), Expect = 0.65
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 5/130 (3%)
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
+ VR +A Y C+ + GP ++ T+ + + + A E+ + C
Sbjct: 288 LTQVRPRNAGIYRCIGQGQRGPPI--ILEATLHLAEIEDMPLFEPRVFTAGSEE--RVTC 343
Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS-LTEEHSGNYSCEANNGLGAQRSE 288
+G P W+ H + L + G L+ + E +G Y+C A N G +R +
Sbjct: 344 LPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQD 403
Query: 289 AVTLNFTVPT 298
TVP+
Sbjct: 404 VNITVATVPS 413
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 61.6 bits (148), Expect = 1e-09
Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 31/321 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQ---INVHRVP-VADVSLETQPPGG---Q 123
L I + +ED+G+Y CEA+ L S+RS ++V P ++ LE+ G +
Sbjct: 123 LTILIVQREDSGTYQCEAR----DALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVE 178
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
VMEG + + + W+ L T + I +V Y C
Sbjct: 179 VMEGSSMTFLAE-TKSHPPCAYTWF-------LLDSILSHTTRTFTIHAVSREHEGLYRC 230
Query: 184 VAENGYGPSPSGLVSI-TVRIPVSRPILMLR-APRAQAAVEDV--LELHCEALRGSPPIL 239
+ N S + L S+ T+++ V + M + P + VE+ ++L C+ + S +
Sbjct: 231 LVSN----SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQ 286
Query: 240 YWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP- 297
++ + + S + + L +G Y+CE N RSE + L P
Sbjct: 287 WFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQ 346
Query: 298 TGARSNHLTSGVIEGLLSTLGPATVALLFCY-GLKRKIGRRSARDPLRSLPSPLPQEFTY 356
+ + S+ +G++ G+L+ + A+ F Y R+ R++ DP P+P+E +
Sbjct: 347 SSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKE-EH 405
Query: 357 LNSPTPGQLQPIYENVNVVSG 377
P+ L P Y N++ + G
Sbjct: 406 PTEPSSESLSPEYCNISQLQG 426
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 61.6 bits (148), Expect = 1e-09
Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 31/321 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQ---INVHRVP-VADVSLETQPPGG---Q 123
L I + +ED+G+Y CEA+ L S+RS ++V P ++ LE+ G +
Sbjct: 123 LTILIVQREDSGTYQCEAR----DALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVE 178
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
VMEG + + + W+ L T + I +V Y C
Sbjct: 179 VMEGSSMTFLAE-TKSHPPCAYTWF-------LLDSILSHTTRTFTIHAVSREHEGLYRC 230
Query: 184 VAENGYGPSPSGLVSI-TVRIPVSRPILMLR-APRAQAAVEDV--LELHCEALRGSPPIL 239
+ N S + L S+ T+++ V + M + P + VE+ ++L C+ + S +
Sbjct: 231 LVSN----SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQ 286
Query: 240 YWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP- 297
++ + + S + + L +G Y+CE N RSE + L P
Sbjct: 287 WFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQ 346
Query: 298 TGARSNHLTSGVIEGLLSTLGPATVALLFCY-GLKRKIGRRSARDPLRSLPSPLPQEFTY 356
+ + S+ +G++ G+L+ + A+ F Y R+ R++ DP P+P+E +
Sbjct: 347 SSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKE-EH 405
Query: 357 LNSPTPGQLQPIYENVNVVSG 377
P+ L P Y N++ + G
Sbjct: 406 PTEPSSESLSPEYCNISQLQG 426
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 60.8 bits (146), Expect = 2e-09
Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 16/224 (7%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+IA ED G+Y C A+ A + R + V V +E P EG
Sbjct: 2810 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 2863
Query: 130 LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C A G+ + W K G + K + E + ++ DA Y C AEN
Sbjct: 2864 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 2922
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
G + + + +PV + R+ R + D L L C A RGSP P + W ++
Sbjct: 2923 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 2977
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
S GG +++ E SG Y C A N +G R++AV+
Sbjct: 2978 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVS 3019
Score = 60.1 bits (144), Expect = 4e-09
Identities = 68/245 (27%), Positives = 94/245 (38%), Gaps = 25/245 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P LQ+ A+ D+G+Y C A + A + R Q+ V P + S QP
Sbjct: 2257 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 2312
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G + L+C A GT W+K L R+ +R DA
Sbjct: 2313 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 2365
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
Y C+AE SP+G + + R+ V P I+ R PR L L C P
Sbjct: 2366 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 2420
Query: 238 ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
+ W H D + A P G +L+ SG+YSC A N G+
Sbjct: 2421 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 2478
Query: 294 FTVPT 298
TVPT
Sbjct: 2479 HTVPT 2483
Score = 55.5 bits (132), Expect = 9e-08
Identities = 61/246 (24%), Positives = 93/246 (37%), Gaps = 19/246 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
LQ AA+ +ED+G+Y C A+ + S ++V PV S +P GG +
Sbjct: 2991 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 3046
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C V G W K + L + I DA +Y C+AEN
Sbjct: 3047 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 3101
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + + + + S P+ + D + L C+A P + W
Sbjct: 3102 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 3157
Query: 248 TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
SR + S L E +G Y C A+N LG+ + A + P G+ +
Sbjct: 3158 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS--M 3215
Query: 307 SGVIEG 312
+GVI G
Sbjct: 3216 TGVING 3221
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G+Y CE + S+ Q+ VH P ++ +PP + D + + A G
Sbjct: 1040 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 1095
Query: 142 DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
T W + +GL LQ++ Q + + + +Y CVAEN G +
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 1150
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
++V +P + AA+ L L CEA+ PP + WF E+ ++ G +
Sbjct: 1151 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 1209
Query: 255 PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
GG ++ T+E SG YSC A+N G R
Sbjct: 1210 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 1242
Score = 53.9 bits (128), Expect = 3e-07
Identities = 65/256 (25%), Positives = 96/256 (37%), Gaps = 26/256 (10%)
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+S P LQI + D G Y C A +A + R ++ V ++E P V
Sbjct: 653 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 706
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
+E + L C +A G W+KG ++ S+ I + SDA Y C
Sbjct: 707 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 765
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
VA N G + + +R+ V I + + V + L C A P L W
Sbjct: 766 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 822
Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
G+ +P+G GG L S SG YSC A + +G R + V L
Sbjct: 823 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQV 876
Query: 295 TVPTGARSNHLTSGVI 310
+P L V+
Sbjct: 877 HMPPSILGEELNVSVV 892
Score = 52.4 bits (124), Expect = 8e-07
Identities = 77/291 (26%), Positives = 109/291 (37%), Gaps = 37/291 (12%)
Query: 32 SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
+PV LTC P + S A Q A G G+ SP L+I G Y
Sbjct: 2681 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 2734
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A+ A + + + V PV ++ P + + + ++L C A G T
Sbjct: 2735 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2787
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
W K + + TQ + I DA Y C+A+N G S G + V++P
Sbjct: 2788 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 2846
Query: 205 VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
P++ P L C+A RGSP P + W G+ PSG
Sbjct: 2847 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2902
Query: 260 ASFNLSLTEEHSGNYSCEANNGLGAQRSEA-----VTLNFTVPTGARSNHL 305
NL + +G Y+C A N +G R V FT G RS L
Sbjct: 2903 LVKNLE--GQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL 2951
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 35/240 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV------ 124
LQI KED G Y C + ++ N H + S+ P G+V
Sbjct: 1406 LQILNAQKEDAGQYTCVVTNELGEAVK------NYHVEVLIPPSISKDDPLGEVGVKEVK 1459
Query: 125 -MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYY 182
L L C + T WYK + S+ Q +I + SD+ +Y
Sbjct: 1460 TKVNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 1518
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE-------- 226
CVA N G + P+ + + ++ R A+ V + E
Sbjct: 1519 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY 1578
Query: 227 LHCEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
L+C+ PP L W Y ED ++ G + GG + L E++G YSC+A+N +G
Sbjct: 1579 LYCDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1637
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
+P EL L T G+P+ L C Q + +D +AL ++S ++
Sbjct: 2310 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 2358
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
+ D G Y C A++ A + +S R ++ V P G + + G +LV
Sbjct: 2359 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 2409
Query: 132 LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
L CSV A IT W++ + L + TQ + ++ ++ +D+ Y C A N
Sbjct: 2410 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 2466
Query: 190 GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G S+ R+ + P + P +V L C+A P++ W + +
Sbjct: 2467 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 2521
Query: 249 LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
L RS P G S + + + +G+Y C A+N G+ R
Sbjct: 2522 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 2562
Score = 46.6 bits (109), Expect = 4e-05
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 20/249 (8%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+I D G Y C+ +A + +R+ + +VP + +T+ + G
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV---QVPPTFENPKTETV--SQVAGSP 1950
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA---EYEIPSVRESDAEQYYCVAE 186
LVL C V+ G T W K + ++S + + ++ ++ + A Y CVAE
Sbjct: 1951 LVLTCDVS-GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 2007
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
N + V + P R + R E + L CEA PP + W +
Sbjct: 2008 NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQE--VRLDCEADGQPPPDVAWL-KDG 2064
Query: 247 ITLGSRSAPS-----GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
LG P GG+ L +G Y+C A+N G + + T+N VP +
Sbjct: 2065 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVPPTIK 2123
Query: 302 SNHLTSGVI 310
SG +
Sbjct: 2124 QGADGSGTL 2132
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+LQ+ D G Y C+A ++ R + V P +P + + G
Sbjct: 366 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 422
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
+ L C VA G T W+ GL + + L + + S E+ + Y CVA
Sbjct: 423 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 479
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
+ P+ ++ +V + V +L+ + V LEL C+A P + W +
Sbjct: 480 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 536
Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
E++ G + A G + ++ E +HSG ++C+A N G +E
Sbjct: 537 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 581
Score = 43.9 bits (102), Expect = 3e-04
Identities = 66/280 (23%), Positives = 105/280 (37%), Gaps = 19/280 (6%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
E +P L C + D ++R+ + L G S LQI + E+ G Y
Sbjct: 1573 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 1628
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C+A + ++ V PV E V + L C A+G T
Sbjct: 1629 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 1685
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
W + + + + Q + ++ + +DA Y CVAEN G S T+R+
Sbjct: 1686 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 1742
Query: 204 PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
V I L + A + + L C+ P + W+ + ++LG G +
Sbjct: 1743 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1802
Query: 263 NLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
L SG Y+CEA N G + + V L+ VP R
Sbjct: 1803 QLGRARLSDSGMYTCEALNAAGRDQ-KLVQLSVLVPPAFR 1841
Score = 38.5 bits (88), Expect = 0.012
Identities = 63/277 (22%), Positives = 117/277 (42%), Gaps = 21/277 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
GSP+ LTC + + + + + ++ A+ S +LQ++ + G+Y C A+
Sbjct: 1948 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 2007
Query: 90 TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
++ + + V R+ + V+ E V+EG + L C D+ +L
Sbjct: 2008 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 2062
Query: 148 YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
+G ++ + L + +R SDA Y CVA N G + L ++ V +P
Sbjct: 2063 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 2119
Query: 207 RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
P + A + V +++ + C +RGSPPI + + + L R+ G G +
Sbjct: 2120 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 2177
Query: 262 FNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
+S + +G ++C A + G TL VP
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAGV-ADRNFTLQVQVP 2213
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 60.8 bits (146), Expect = 2e-09
Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 16/224 (7%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+IA ED G+Y C A+ A + R + V V +E P EG
Sbjct: 2719 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 2772
Query: 130 LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C A G+ + W K G + K + E + ++ DA Y C AEN
Sbjct: 2773 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 2831
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
G + + + +PV + R+ R + D L L C A RGSP P + W ++
Sbjct: 2832 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 2886
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
S GG +++ E SG Y C A N +G R++AV+
Sbjct: 2887 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVS 2928
Score = 60.1 bits (144), Expect = 4e-09
Identities = 68/245 (27%), Positives = 94/245 (38%), Gaps = 25/245 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P LQ+ A+ D+G+Y C A + A + R Q+ V P + S QP
Sbjct: 2166 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 2221
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G + L+C A GT W+K L R+ +R DA
Sbjct: 2222 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 2274
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
Y C+AE SP+G + + R+ V P I+ R PR L L C P
Sbjct: 2275 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 2329
Query: 238 ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
+ W H D + A P G +L+ SG+YSC A N G+
Sbjct: 2330 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 2387
Query: 294 FTVPT 298
TVPT
Sbjct: 2388 HTVPT 2392
Score = 55.5 bits (132), Expect = 9e-08
Identities = 61/246 (24%), Positives = 93/246 (37%), Gaps = 19/246 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
LQ AA+ +ED+G+Y C A+ + S ++V PV S +P GG +
Sbjct: 2900 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 2955
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C V G W K + L + I DA +Y C+AEN
Sbjct: 2956 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAEN 3010
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + + + + S P+ + D + L C+A P + W
Sbjct: 3011 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 3066
Query: 248 TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
SR + S L E +G Y C A+N LG+ + A + P G+ +
Sbjct: 3067 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS--M 3124
Query: 307 SGVIEG 312
+GVI G
Sbjct: 3125 TGVING 3130
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G+Y CE + S+ Q+ VH P ++ +PP + D + + A G
Sbjct: 949 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 1004
Query: 142 DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
T W + +GL LQ++ Q + + + +Y CVAEN G +
Sbjct: 1005 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 1059
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
++V +P + AA+ L L CEA+ PP + WF E+ ++ G +
Sbjct: 1060 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 1118
Query: 255 PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
GG ++ T+E SG YSC A+N G R
Sbjct: 1119 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 1151
Score = 53.9 bits (128), Expect = 3e-07
Identities = 65/256 (25%), Positives = 96/256 (37%), Gaps = 26/256 (10%)
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+S P LQI + D G Y C A +A + R ++ V ++E P V
Sbjct: 562 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 615
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
+E + L C +A G W+KG ++ S+ I + SDA Y C
Sbjct: 616 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 674
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
VA N G + + +R+ V I + + V + L C A P L W
Sbjct: 675 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 731
Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
G+ +P+G GG L S SG YSC A + +G R + V L
Sbjct: 732 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQV 785
Query: 295 TVPTGARSNHLTSGVI 310
+P L V+
Sbjct: 786 HMPPSILGEELNVSVV 801
Score = 52.4 bits (124), Expect = 8e-07
Identities = 77/291 (26%), Positives = 109/291 (37%), Gaps = 37/291 (12%)
Query: 32 SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
+PV LTC P + S A Q A G G+ SP L+I G Y
Sbjct: 2590 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 2643
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A+ A + + + V PV ++ P + + + ++L C A G T
Sbjct: 2644 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2696
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
W K + + TQ + I DA Y C+A+N G S G + V++P
Sbjct: 2697 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 2755
Query: 205 VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
P++ P L C+A RGSP P + W G+ PSG
Sbjct: 2756 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2811
Query: 260 ASFNLSLTEEHSGNYSCEANNGLGAQRSEA-----VTLNFTVPTGARSNHL 305
NL + +G Y+C A N +G R V FT G RS L
Sbjct: 2812 LVKNLE--GQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL 2860
Score = 49.3 bits (116), Expect = 7e-06
Identities = 66/268 (24%), Positives = 106/268 (39%), Gaps = 23/268 (8%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS--SPK---LQIAAMWKEDTGSY 84
+G L C + + Q + +F+D R L G + SP LQ+ G Y
Sbjct: 1177 DGQTAHLMCNV----TGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232
Query: 85 WCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLIC-SVAMGTGD 142
C A + +++ Q++V P + + ++ V + + LIC ++A + +
Sbjct: 1233 SCIAANAVGE--KTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 1290
Query: 143 ITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITV 201
IT W K Q T +I + ++ DA QY CV N G + + V
Sbjct: 1291 IT--WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNY-HVEV 1347
Query: 202 RIPVS----RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH-EDITLGSRSAPS 256
IP S P+ + + V L L CE+ PP + W+ + +T SR
Sbjct: 1348 LIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVL 1407
Query: 257 GGGASFNLSLTE-EHSGNYSCEANNGLG 283
G G + T+ SG Y C A N G
Sbjct: 1408 GEGRLLQIQPTQVSDSGRYLCVATNVAG 1435
Score = 48.9 bits (115), Expect = 9e-06
Identities = 56/238 (23%), Positives = 94/238 (39%), Gaps = 31/238 (13%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRV-----PVADVSLETQPPGGQVM 125
LQI KED G Y C + +++ ++ + P+A+V ++ +
Sbjct: 1315 LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEV----KTK 1370
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCV 184
L L C + T WYK + S+ Q +I + SD+ +Y CV
Sbjct: 1371 VNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 1429
Query: 185 AENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE--------LH 228
A N G + P+ + + ++ R A+ V + E L+
Sbjct: 1430 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1489
Query: 229 CEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
C+ PP L W Y ED ++ G + GG + L E++G YSC+A+N +G
Sbjct: 1490 CDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1546
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
+P EL L T G+P+ L C Q + +D +AL ++S ++
Sbjct: 2219 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 2267
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
+ D G Y C A++ A + +S R ++ V P G + + G +LV
Sbjct: 2268 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 2318
Query: 132 LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
L CSV A IT W++ + L + TQ + ++ ++ +D+ Y C A N
Sbjct: 2319 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 2375
Query: 190 GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G S+ R+ + P + P +V L C+A P++ W + +
Sbjct: 2376 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 2430
Query: 249 LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
L RS P G S + + + +G+Y C A+N G+ R
Sbjct: 2431 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 2471
Score = 46.6 bits (109), Expect = 4e-05
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 20/249 (8%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+I D G Y C+ +A + +R+ + +VP + +T+ + G
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV---QVPPTFENPKTETV--SQVAGSP 1859
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA---EYEIPSVRESDAEQYYCVAE 186
LVL C V+ G T W K + ++S + + ++ ++ + A Y CVAE
Sbjct: 1860 LVLTCDVS-GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 1916
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
N + V + P R + R E + L CEA PP + W +
Sbjct: 1917 NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQE--VRLDCEADGQPPPDVAWL-KDG 1973
Query: 247 ITLGSRSAPS-----GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
LG P GG+ L +G Y+C A+N G + + T+N VP +
Sbjct: 1974 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVPPTIK 2032
Query: 302 SNHLTSGVI 310
SG +
Sbjct: 2033 QGADGSGTL 2041
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+LQ+ D G Y C+A ++ R + V P +P + + G
Sbjct: 275 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 331
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
+ L C VA G T W+ GL + + L + + S E+ + Y CVA
Sbjct: 332 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 388
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
+ P+ ++ +V + V +L+ + V LEL C+A P + W +
Sbjct: 389 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 445
Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
E++ G + A G + ++ E +HSG ++C+A N G +E
Sbjct: 446 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 490
Score = 43.9 bits (102), Expect = 3e-04
Identities = 66/280 (23%), Positives = 105/280 (37%), Gaps = 19/280 (6%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
E +P L C + D ++R+ + L G S LQI + E+ G Y
Sbjct: 1482 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 1537
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C+A + ++ V PV E V + L C A+G T
Sbjct: 1538 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 1594
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
W + + + + Q + ++ + +DA Y CVAEN G S T+R+
Sbjct: 1595 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 1651
Query: 204 PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
V I L + A + + L C+ P + W+ + ++LG G +
Sbjct: 1652 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1711
Query: 263 NLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
L SG Y+CEA N G + + V L+ VP R
Sbjct: 1712 QLGRARLSDSGMYTCEALNAAGRDQ-KLVQLSVLVPPAFR 1750
Score = 38.5 bits (88), Expect = 0.012
Identities = 63/277 (22%), Positives = 117/277 (42%), Gaps = 21/277 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
GSP+ LTC + + + + + ++ A+ S +LQ++ + G+Y C A+
Sbjct: 1857 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 1916
Query: 90 TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
++ + + V R+ + V+ E V+EG + L C D+ +L
Sbjct: 1917 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 1971
Query: 148 YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
+G ++ + L + +R SDA Y CVA N G + L ++ V +P
Sbjct: 1972 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 2028
Query: 207 RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
P + A + V +++ + C +RGSPPI + + + L R+ G G +
Sbjct: 2029 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 2086
Query: 262 FNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
+S + +G ++C A + G TL VP
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAGV-ADRNFTLQVQVP 2122
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 59.7 bits (143), Expect = 5e-09
Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
+T G+Y+C A N +G + A TV G+ H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316
Score = 38.1 bits (87), Expect = 0.015
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.034
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 59.7 bits (143), Expect = 5e-09
Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
+T G+Y+C A N +G + A TV G+ H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316
Score = 38.1 bits (87), Expect = 0.015
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.034
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 59.7 bits (143), Expect = 5e-09
Identities = 77/326 (23%), Positives = 128/326 (39%), Gaps = 29/326 (8%)
Query: 6 LLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW 65
++++ A P + + +S TEG + L C + + A Q ++R +L P
Sbjct: 2040 VVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVV----AGSAHAQVTWYRRGGSLPPHT 2095
Query: 66 S-SSPKLQIAAMWKEDTGSYWCEAQ--------TMASKVLRSRRSQINVHRVPVADVSLE 116
+L++ + D+G Y C + ++ VL S + VP + +
Sbjct: 2096 QVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIR 2155
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
+P V EG L L C V G W+K L + +T SL ++ V +
Sbjct: 2156 IEPSSSHVAEGQTLDLNC-VVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQ---VTPA 2211
Query: 177 DAEQYYCVAENGYGP-SPSGLVSITVR-IPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
D+ +Y C GP S LV+I IP P + + + + A L+L C
Sbjct: 2212 DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2271
Query: 235 SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT--- 291
+ + W Y +L +R G + + +G Y C A+NG+ A + VT
Sbjct: 2272 AHAQVTW-YKRGGSLPARHQVRGSRL-YIFQASPADAGQYVCRASNGMEASITVTVTGTQ 2329
Query: 292 -LNFTVPTGA----RSNHLTSGVIEG 312
N P G+ R +S V EG
Sbjct: 2330 GANLAYPAGSTQPIRIEPSSSQVAEG 2355
Score = 58.2 bits (139), Expect = 1e-08
Identities = 65/278 (23%), Positives = 109/278 (39%), Gaps = 20/278 (7%)
Query: 23 ASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-SSPKLQIAAMWKEDT 81
+S S EG + L C L + A Q + + +L +L++ + D+
Sbjct: 2443 SSSSQVAEGQTLDLNC----LVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADS 2498
Query: 82 GSYWCE----AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
G Y C + T + VL + + +++ + + + G L L C VA
Sbjct: 2499 GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA 2558
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
T WYK G +L S+ Q + + IP V +D+ +Y C NG G + L+
Sbjct: 2559 -SQAPHTITWYKR--GGSLPSRHQ-IVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLI 2614
Query: 198 -----SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
S + +P P + + + L+L+C R I+ W Y +L SR
Sbjct: 2615 VTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITW-YKRGGSLPSR 2673
Query: 253 SAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
G + ++ SG Y C ANN + A + V
Sbjct: 2674 HQTHGSHLRLH-QMSVADSGEYVCRANNNIDALEASIV 2710
Score = 55.1 bits (131), Expect = 1e-07
Identities = 59/239 (24%), Positives = 94/239 (39%), Gaps = 25/239 (10%)
Query: 62 GPGWSSSPKLQI-------AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS 114
GPG K QI A+ D Y C A + A + + R+ ++VH
Sbjct: 1902 GPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVA--RAVLHVHGG--GGPR 1957
Query: 115 LETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVR 174
++ P QV G + L C A G T W K L Q++++R+ A IP++
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAA-GVPSATITWRKEGGSLPPQARSERTDIATLLIPAIT 2016
Query: 175 ESDAEQYYCVAENGYGPSPSGLVSITVRIPV------SRPILMLRAPRAQAAVEDVLELH 228
+DA Y CVA SP+G +++ V S P + + + L+L+
Sbjct: 2017 TADAGFYLCVA-----TSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLN 2071
Query: 229 CEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
C + GS +Y +L + G ++ SG Y C NG G + +
Sbjct: 2072 C-VVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLP-QVSPADSGEYVCRVENGSGPKEA 2128
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/223 (24%), Positives = 87/223 (39%), Gaps = 12/223 (5%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI++ D G+Y C AQ + ++ + ++ + V G
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
L CS A G+ T W K L Q + + IP V + D+ QY C A
Sbjct: 3230 TLRCS-ATGSPAPTIHWSKLRSPLPWQHRLEGDTLI---IPRVAQQDSGQYICNA----- 3280
Query: 191 PSPSGLVSITVRIPVSRPILMLRAP-RAQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
SP+G T+ + V P P A + ++L C A G+PP+ + + +L
Sbjct: 3281 TSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLA-HGTPPLTFQWSRVGSSL 3339
Query: 250 GSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
R+ F + E+ SG Y C N +G+ + A L
Sbjct: 3340 PGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLL 3381
Score = 48.5 bits (114), Expect = 1e-05
Identities = 66/262 (25%), Positives = 104/262 (39%), Gaps = 32/262 (12%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS-----LETQPPGGQVM 125
L I A+ D G Y C A + A + +++I V + +D S +E+ P V
Sbjct: 2010 LLIPAITTADAGFYLCVATSPAG----TAQARIQVVVLSASDASPPPVKIESSSPS--VT 2063
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
EG L L C VA G+ WY+ L ++ S +P V +D+ +Y C
Sbjct: 2064 EGQTLDLNCVVA-GSAHAQVTWYRRGGSLPPHTQVHGS---RLRLPQVSPADSGEYVCRV 2119
Query: 186 ENGYGPSPSGL-VSIT---------VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGS 235
ENG GP + + VS+ +P S + + + A L+L+C + G
Sbjct: 2120 ENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNC-VVPGQ 2178
Query: 236 PPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTLNF 294
++ +L +R G + +T SG Y C G + S VT+
Sbjct: 2179 AHAQVTWHKRGGSLPARHQTHGSLLRLH-QVTPADSGEYVCHVVGTSGPLEASVLVTIEA 2237
Query: 295 TVPTG----ARSNHLTSGVIEG 312
+V G R +S V EG
Sbjct: 2238 SVIPGPIPPVRIESSSSTVAEG 2259
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/201 (24%), Positives = 87/201 (43%), Gaps = 19/201 (9%)
Query: 19 LFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRAL-GPGWSSSPKLQIAAMW 77
+++ AS SH TEG + L C +P A Q +++ +L + +L++ +
Sbjct: 2927 IYIEASSSHVTEGQTLDLNCVVP----GQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVS 2982
Query: 78 KEDTGSYWCEA------QTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
D+G Y C A + AS + S+ + +R+ +S++ PP V +G
Sbjct: 2983 PADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISID--PPSSTVQQGQDAS 3040
Query: 132 LICSVAMGTGDITFLWYKGAVGL--NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGY 189
C + G I+ W L N+ S+ I R S+ Y CVA N Y
Sbjct: 3041 FKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIIT---IVGTRPSNHGTYRCVASNAY 3097
Query: 190 GPSPSGLVSITVRIPVSRPIL 210
G + S +V+++V P + +L
Sbjct: 3098 GVAQS-VVNLSVHGPPTVSVL 3117
Score = 46.6 bits (109), Expect = 4e-05
Identities = 71/304 (23%), Positives = 117/304 (38%), Gaps = 28/304 (9%)
Query: 23 ASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS-SPKLQIAAMWKEDT 81
+S SH EG + L C +P A Q + + +L + +L++ + D+
Sbjct: 2733 SSSSHVAEGETLDLNCVVP----GQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADS 2788
Query: 82 GSYWCEAQTM-----ASKVLRSRRSQINVHRVPVADVS--LETQPPGGQVMEGDRLVLIC 134
G Y C AS ++ S + VP + + +P +V EG L L C
Sbjct: 2789 GEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKC 2848
Query: 135 SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGP-SP 193
V G W+K L + + L + V +D+ +Y C G
Sbjct: 2849 -VVPGQAHAQVTWHKRGGNLPARHQVHGPLL---RLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 194 SGLVSITVRIPVSRPI------LMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
S LV+I P P + + A + L+L+C + G +Y
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VVPGQAHAQVTWYKRGG 2963
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH-LT 306
+L +R G +L ++ SG Y C A +G G ++ + T+ TVP S++ L
Sbjct: 2964 SLPARHQTHGSQLRLHL-VSPADSGEYVCRAASGPGPEQEASFTV--TVPPSEGSSYRLR 3020
Query: 307 SGVI 310
S VI
Sbjct: 3021 SPVI 3024
Score = 45.4 bits (106), Expect = 1e-04
Identities = 66/264 (25%), Positives = 105/264 (39%), Gaps = 28/264 (10%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-SSPKLQIAAMWKEDTGSYWCEAQ 89
G+ V C +P SD Q +F++ L PG S L+I + + G+Y C+A
Sbjct: 3414 GASVEFHCAVP----SDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAH 3469
Query: 90 TMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYK 149
K S +Q+ + +P +++ T V+ G + C +A+G W K
Sbjct: 3470 GPWGKAQAS--AQLVIQALPSVLINIRTSVQ--TVVVGHAVEFEC-LALGDPKPQVTWSK 3524
Query: 150 GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPI 209
VG +L+ +S I V +DA QY C A N G + S ++ + +P
Sbjct: 3525 --VGGHLRPGIVQS-GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMP 3581
Query: 210 LMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNL----S 265
+R P AAV C A P + W + S P N+ S
Sbjct: 3582 QEVRVPAGSAAV-----FPCIASGYPTPDISWSKLDG------SLPPDSRLENNMLMLPS 3630
Query: 266 LTEEHSGNYSCEANNGLGAQRSEA 289
+ + +G Y C A N G ++ A
Sbjct: 3631 VRPQDAGTYVCTATNRQGKVKAFA 3654
Score = 45.1 bits (105), Expect = 1e-04
Identities = 58/289 (20%), Positives = 107/289 (37%), Gaps = 17/289 (5%)
Query: 10 CAPLCEPAELFLIASPSHPT--EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS 67
C P A L + P+ +G +L C++ S + + D R + G
Sbjct: 1668 CLPETNQAPLVVEVHPARSIVPQGGSHSLRCQV---SGSPPHYFYWSREDGRPVPSGTQQ 1724
Query: 68 ---SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ- 123
+L ++ D G Y C + + + R+++ V P +++ + Q
Sbjct: 1725 RHQGSELHFPSVQPSDAGVYICTCRNLHQS--NTSRAELLVTEAPSKPITVTVEEQRSQS 1782
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
V G + IC+ + T +W + G L ++ I +V+ SDA Y C
Sbjct: 1783 VRPGADVTFICTAKSKSPAYTLVWTRLHNG-KLPTRAM-DFNGILTIRNVQLSDAGTYVC 1840
Query: 184 VAENGYGPSPSGLVSITVRIP--VSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
N + G ++ V+ +S P++ + P+ + E C A P L W
Sbjct: 1841 TGSNMFAMD-QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899
Query: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
L +++ GG ++ Y C A++ G Q + AV
Sbjct: 1900 TGGPGGQLPAKAQIHGGILRLP-AVEPTDQAQYLCRAHSSAGQQVARAV 1947
Score = 35.4 bits (80), Expect = 0.10
Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 15/167 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQIN--VHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
G+Y C +AS +S +N VH P V P G ++ + V + V+ G
Sbjct: 3087 GTYRC----VASNAYGVAQSVVNLSVHGPPTVSVL----PEGPVWVKVGKAVTLECVSAG 3138
Query: 140 TGDITFLWYK-GAVGLNLQSKTQRSLT--AEYEIPSVRESDAEQYYCVAENGYGPSPSGL 196
+ W + + L+ +T + A +I S + SDA Y C+A+N G + +
Sbjct: 3139 EPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQV 3198
Query: 197 VSITVRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPILYW 241
I ++ ++A A+ VE L C A P ++W
Sbjct: 3199 EVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW 3245
Score = 32.3 bits (72), Expect = 0.85
Identities = 45/230 (19%), Positives = 78/230 (33%), Gaps = 22/230 (9%)
Query: 79 EDTGSYWCE-------AQTMASKVLRSRRSQINVHRVPVADV-SLETQPPGGQVMEGDRL 130
ED+G Y C A+ A +++ + +P +++ P G +
Sbjct: 3358 EDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASV 3417
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
C+V G W+K L Q + I ++ +S Y C A +G
Sbjct: 3418 EFHCAVPSDRGT-QLRWFKEGGQLPPGHSVQDGVL---RIQNLDQSCQGTYICQAHGPWG 3473
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLG 250
+ + + +P ++ +R V +E C AL P + W +G
Sbjct: 3474 KAQASAQLVIQALP--SVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWS-----KVG 3526
Query: 251 SRSAPS---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
P GG + +G Y C A N G +S + L +P
Sbjct: 3527 GHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3576
Score = 29.6 bits (65), Expect = 5.5
Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 21/156 (13%)
Query: 218 QAAVEDVLELHCEALRGSPPILYWFY-------HEDITLGSRSAPSGGGASFNLSLTEEH 270
QA+ + C A+ PI+ W H +T+ S G G + E
Sbjct: 417 QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEG---GRGTLIIRDVKESD 473
Query: 271 SGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVI-EGLLSTLGPATVALLFCYG 329
G Y+CEA N G + F +P G G +G A FC+G
Sbjct: 474 QGAYTCEAMNARG--------MVFGIPDGVLELVPQRGPCPDGHFYLEHSAACLPCFCFG 525
Query: 330 LKRKI-GRRSARDPLRSLPSPLPQEFTYLNSPTPGQ 364
+ R RD +R L P +F +N P Q
Sbjct: 526 ITSVCQSTRRFRDQIR-LRFDQPDDFKGVNVTMPAQ 560
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 59.7 bits (143), Expect = 5e-09
Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
+T G+Y+C A N +G + A TV G+ H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316
Score = 38.1 bits (87), Expect = 0.015
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.034
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 59.7 bits (143), Expect = 5e-09
Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
+T G+Y+C A N +G + A TV G+ H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316
Score = 38.1 bits (87), Expect = 0.015
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.034
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 58.9 bits (141), Expect = 8e-09
Identities = 59/229 (25%), Positives = 92/229 (40%), Gaps = 19/229 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I +W D G+Y CEA+ K+ + P+ +S P V+EG +L
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGIS----PSVANVIEGQQL 907
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
L C++ G W K + L I V+ D +Y CVA N G
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 191 ---PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV-LELHCEALRGSPPILYWFYHED 246
+ S +V + I + IL + +E + + L C+A P + W +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGNPKPSVIWSKKGE 1019
Query: 247 ITLGSRSAPSGG--GASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
+ S + S G G+ + +S E SG Y C A N G A+R +T+
Sbjct: 1020 LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.4 bits (137), Expect = 2e-08
Identities = 70/256 (27%), Positives = 102/256 (39%), Gaps = 20/256 (7%)
Query: 33 PVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS----SSPKLQIAAMWKEDTGSYWCEA 88
P+TL+C+ L D + +D RA+ SS LQIA + D G Y C A
Sbjct: 4095 PITLSCEADGLPPPDITWH----KDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMA 4150
Query: 89 QTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWY 148
+A S +++ VH P + + V E + +L C VA G W
Sbjct: 4151 ANVAGS--SSTSTKLTVHVPP----RIRSTEGHYTVNENSQAILPC-VADGIPTPAINWK 4203
Query: 149 KGAVGL-NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
K V L NL K E + +V D+ Y CVA N G + VS+TV +
Sbjct: 4204 KDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGED-THTVSLTVHV---L 4259
Query: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
P + L L C+A P L W ++ +I + +G ++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVS 4319
Query: 268 EEHSGNYSCEANNGLG 283
+E SG Y C A N +G
Sbjct: 4320 KEDSGTYVCTAENSVG 4335
Score = 52.0 bits (123), Expect = 1e-06
Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 24/232 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI+ +ED G+Y C AQ A L + ++NV PV L+ V+ D+
Sbjct: 4043 LQISRAVREDAGTYMCVAQNPAGTAL--GKIKLNVQVPPVISPHLKE-----YVIAVDKP 4095
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGY 189
+ + A G W+K + ++S QR L++ +I V+ DA Y C+A N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAI-VESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPILYWFYHEDI 247
G S S +TV +P +R+ V + + L C A P + W +
Sbjct: 4155 G-SSSTSTKLTVHVPP-----RIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVL 4208
Query: 248 ---TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
LG +A G ++ E SG Y+C ANN G + T++ TV
Sbjct: 4209 LANLLGKYTAEPYGELILE-NVVLEDSGFYTCVANNAAG---EDTHTVSLTV 4256
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/267 (23%), Positives = 103/267 (38%), Gaps = 20/267 (7%)
Query: 39 KMPFLQSSDAQFQFCFFRDTRALGPGW----SSSPKLQIAAMWKEDTGSYWCEAQTMASK 94
++P S F F R+ LG S+S L IA + D G Y C A + A
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGT 507
Query: 95 VLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGL 154
++ PV V P V G+R VL C + D W + +
Sbjct: 508 GRAQTFFDVS-EPPPVIQV-----PNNVTVTPGERAVLTCLIISAV-DYNLTWQRNDRDV 560
Query: 155 NLQSKTQRSLTAEY--EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILML 212
L + A E+ SV+ +DA +Y+C+ + G S + V +TV+ P ++
Sbjct: 561 RLAEPARIRTLANLSLELKSVKFNDAGEYHCMV-SSEGGSSAASVFLTVQEPPKVTVM-- 617
Query: 213 RAPRAQAAV-EDVLELHCEALRGSPPILYWFYHEDITLGS-RSAPSGGGASFNLSLTEEH 270
P+ Q+ + + C A P + W ++ +GS R + G F + +
Sbjct: 618 --PKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKD 675
Query: 271 SGNYSCEANNGLGAQRSEAVTLNFTVP 297
+G Y C A+N G + + P
Sbjct: 676 AGIYGCLASNSAGTDKQNSTLRYIEAP 702
Score = 47.4 bits (111), Expect = 3e-05
Identities = 69/289 (23%), Positives = 109/289 (37%), Gaps = 42/289 (14%)
Query: 30 EGSPVTLTCKM--------------PFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAA 75
EG PVTL CK + +S A+F + L + +
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA-------------GADGSLYVVS 1040
Query: 76 MWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS--LETQPPGGQVMEGDRLVLI 133
E++G Y C A A R + + V D + +P V+ G+ + L
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLP 1100
Query: 134 CSVAMGTGDITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGYGPS 192
C V I W K ++ S L + +I R SD+ Y CVA N
Sbjct: 1101 CEVKSLPPPI-ITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN----- 1154
Query: 193 PSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSP-PILYWFYHEDITL- 249
+G V+ V++ V P + R P+ + V +++ C A +G+P P++ W L
Sbjct: 1155 IAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNA-QGTPLPVITWSKGGSTMLV 1213
Query: 250 -GSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
G + G T +G Y+C A N G +E +TL+ P
Sbjct: 1214 DGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETE-ITLHVQEP 1261
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/282 (24%), Positives = 107/282 (37%), Gaps = 34/282 (12%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-----GWSSSP 69
+P E+ ++A G VTL C++ L + ++T+ + P + S
Sbjct: 1085 KPVEISVLA-------GEEVTLPCEVKSLPPPIITWA----KETQLISPFSPRHTFLPSG 1133
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
++I D+G Y C A +A V ++ ++NVH P ++ P +V G R
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNV--TQAVKLNVHVPP----KIQRGPKHLKVQVGQR 1187
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRS-LTAEYEIPSVRESDAEQYYCVAENG 188
+ + C+ A GT W KG + + + S I SDA Y CVA N
Sbjct: 1188 VDIPCN-AQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNI 1246
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV----LELHCEALRGSPPILYWFYH 244
G + IT+ + + L P E V +E C A P + W ++
Sbjct: 1247 AGTDET---EITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHN 1303
Query: 245 EDITLGSR---SAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
G S G S+T +G Y C A N G
Sbjct: 1304 GRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 47.4 bits (111), Expect = 3e-05
Identities = 60/226 (26%), Positives = 91/226 (40%), Gaps = 12/226 (5%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
S +LQI+ K D Y C A +A + Q+ + S T+ V
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEII---VT 2305
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY--EIPSVRESDAEQYYC 183
G + L C V G T W K L +++K L + ++ ++ SD +Y C
Sbjct: 2306 RGKSISLECEV-QGIPPPTVTWMKDGHPL-IKAKGVEILDEGHILQLKNIHVSDTGRYVC 2363
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWF 242
VA N G + ++V P S I R+P + VE + + L CEA P + WF
Sbjct: 2364 VAVNVAGMTDKKY-DLSVHAPPSI-IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWF 2421
Query: 243 YHE-DITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQR 286
++L + GG L T E +G Y+C N G +R
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Score = 46.6 bits (109), Expect = 4e-05
Identities = 70/245 (28%), Positives = 97/245 (39%), Gaps = 32/245 (13%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLET--QPPGGQ 123
SS LQIA ED G Y C A A + + Q++VH P SLE +
Sbjct: 1878 SSGRVLQIAKTLLEDAGRYTCVATNAAGET--QQHIQLHVHEPP----SLEDAGKMLNET 1931
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESD 177
V+ + + L C A G WYK G+ + ++ Q +I S + SD
Sbjct: 1932 VLVSNPVQLECKAA-GNPVPVITWYKDNRLLSGSTSMTFLNRGQ-----IIDIESAQISD 1985
Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP- 236
A Y CVA N G + S+ V + P + V + + L CEA RG P
Sbjct: 1986 AGIYKCVAINSAGATEL-FYSLQVHV---APSISGSNNMVAVVVNNPVRLECEA-RGIPA 2040
Query: 237 PILYWFYHEDITLGSRS----APSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
P L W + + S S SGG S +G Y+C A N G ++ + L
Sbjct: 2041 PSLTWL-KDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG-EKQRDIDL 2098
Query: 293 NFTVP 297
VP
Sbjct: 2099 RVYVP 2103
Score = 46.6 bits (109), Expect = 4e-05
Identities = 65/240 (27%), Positives = 87/240 (36%), Gaps = 33/240 (13%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I + DTG Y C A A RR + VH P S+ P V+ +
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGT--DRRRIDLQVHVPP----SIAPGPTNMTVIVNVQT 3821
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNL---QSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C A G + W K LN+ Q+ + + I S D Y C N
Sbjct: 3822 TLACE-ATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 188 GYGPSPSGLVSITVRIPVS---RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
G G V +TV++P S P L A A + C A P ++W +
Sbjct: 3881 GAGDDKR-TVDLTVQVPPSIADEPTDFLVTKHAPAVIT------CTASGVPFPSIHWTKN 3933
Query: 245 EDITLGSRSAPSG-------GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
G R P G GA L+ H+G Y+C A N G+ VTL+ P
Sbjct: 3934 -----GIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRH-VTLHVHEP 3987
Score = 45.8 bits (107), Expect = 7e-05
Identities = 74/295 (25%), Positives = 124/295 (42%), Gaps = 37/295 (12%)
Query: 24 SPSHPTE-----GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-WSSSPKLQIAAMW 77
S SHPTE G ++L C++ + + +A G LQ+ +
Sbjct: 2295 SGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH 2354
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
DTG Y C A +A + ++ ++VH P + + P V+E + + L C A
Sbjct: 2355 VSDTGRYVCVAVNVAG--MTDKKYDLSVH-APPSIIGNHRSPENISVVEKNSVSLTCE-A 2410
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES--DAEQYYCVAENGYGPSPSG 195
G + W+K ++L S + R L+ + ++ + DA QY CV N G
Sbjct: 2411 SGIPLPSITWFKDGWPVSL-SNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERK- 2468
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDV-------LELHCEALRGSPPILYWFYHED-I 247
+ ++V +P P ++ + +EDV + L CE P + W H+D
Sbjct: 2469 IFGLSVLVP---PHIV-----GENTLEDVKVKEKQSVTLTCEVTGNPVPEITW--HKDGQ 2518
Query: 248 TLGSRSAP---SGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN-FTVPT 298
L A SGG ++ H+G Y+C A++ G +S + +LN F PT
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG-HKSRSFSLNVFVSPT 2572
Score = 45.1 bits (105), Expect = 1e-04
Identities = 67/255 (26%), Positives = 98/255 (38%), Gaps = 26/255 (10%)
Query: 79 EDTGSYWCEAQTMA-SKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+D G Y C A A + S I ++ V L V GD V+ C +
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSEL-------LVALGDITVMECKTS 726
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR---SLTAEYEIPSVRESDAEQYYCVAENGYGPSPS 194
G W+KG L L+ T L +I ++ DA Y CVA N G + +
Sbjct: 727 -GIPPPQVKWFKG--DLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRA-T 782
Query: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
G +++ V P P+ + + + L C P + W +++ + SR
Sbjct: 783 GKITLDVGSP---PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPF 839
Query: 255 PSGG------GASFNLSLTEEHSGNYSCEANNGLGAQRSE-AVTLNFTVPTGARSNHLTS 307
GA F L+L G Y CEA N G +SE VT+ V + +
Sbjct: 840 SVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Query: 308 GVIEGLLSTLGPATV 322
VIEG TL P T+
Sbjct: 900 NVIEGQQLTL-PCTL 913
Score = 45.1 bits (105), Expect = 1e-04
Identities = 61/248 (24%), Positives = 93/248 (37%), Gaps = 20/248 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I D+ +Y C +A +S ++V+ P+ + +L T P QV+ L
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVAGTAEKS--FHVDVYVPPMIEGNLAT-PLNKQVVIAHSL 1659
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE-YEIPSVRESDAEQYYCVAENGY 189
L C A G W K V + + + EI S +E D QY CVA
Sbjct: 1660 TLECKAA-GNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT--- 1715
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQ---AAVEDVLELHCEALRGSPPILYWFYHED 246
S +G I + V P + V ++LEL C PP + W
Sbjct: 1716 --SVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQ 1773
Query: 247 ITLGSRSAPS---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSE-AVTLNFTVPTGARS 302
+ + R G ++G Y C A N G + E VT++ VP +S
Sbjct: 1774 L-IDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH--VPPTIKS 1830
Query: 303 NHLTSGVI 310
+ L+ V+
Sbjct: 1831 SGLSERVV 1838
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 24/231 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS----LETQPPGGQVME 126
LQI +++ G Y C A A ++++ ++ V+ P+ + P ++
Sbjct: 2631 LQILNAQEDNAGRYSCVATNEAGEMIK--HYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRE---SDAEQYYC 183
+ L L C A + WYK G L+S ++ A ++E SD +Y C
Sbjct: 2689 NNTLTLECE-AYAIPSASLSWYKD--GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTC 2745
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPIL-----MLRAPRAQAA----VEDVLELHCEALRG 234
VA N G + +++P S L ML R A + + + L+CE
Sbjct: 2746 VASNIAGEDELDF-DVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAA 2804
Query: 235 SPPILYWFYH-EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
PP L W+ +T + GG + + E +G Y+C A N G
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 45.1 bits (105), Expect = 1e-04
Identities = 57/237 (24%), Positives = 97/237 (40%), Gaps = 12/237 (5%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI ED G Y C A A + S + + V P+ + P V+
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGE--DSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSA 2890
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE--YEIPSVRESDAEQYYCVAENG 188
++ C ++ G+ W K L L+ + L+ +I + + +D +Y CVAEN
Sbjct: 2891 LIEC-LSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITDIGRYVCVAENT 2948
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-I 247
G S ++ V +P S ++ ++ V + + L CE PP L W +E I
Sbjct: 2949 AG-SAKKYFNLNVHVPPS--VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPI 3005
Query: 248 TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSN 303
L + + GG + + + G Y+C A N G + + +L VP + +
Sbjct: 3006 KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK-FSLTVYVPPSIKDH 3061
Score = 44.3 bits (103), Expect = 2e-04
Identities = 62/250 (24%), Positives = 98/250 (39%), Gaps = 24/250 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI D G Y C A A + ++ + V+ P V EG +
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGE--SKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSV 3077
Query: 131 VLIC-SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRE---SDAEQYYCVAE 186
L C S A+ IT WYK G + T + A+ ++ +++ SD QY C A
Sbjct: 3078 SLECESNAVPPPVIT--WYKN--GRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAI 3133
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV---LELHCEALRGSPPILYWFY 243
N G + V +P S + P + VE + + L C+A PP + W
Sbjct: 3134 NVAGRDDKNF-HLNVYVPPS-----IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK 3187
Query: 244 HEDITLGSRSAPS---GGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVTLNFTVPTG 299
+ S S GG+ ++ ++ SGNY+C A+N + + + L+ VP
Sbjct: 3188 NHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN-MEGKAQKYYFLSIQVPPS 3246
Query: 300 ARSNHLTSGV 309
+ S V
Sbjct: 3247 VAGAEIPSDV 3256
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 23/221 (10%)
Query: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGG-QVMEGDRLVLIC-SV 136
ED+G Y C A A + + + VH +P T+ PG + +G++L L C +
Sbjct: 4232 EDSGFYTCVANNAAGE--DTHTVSLTVHVLPTF-----TELPGDVSLNKGEQLRLSCKAT 4284
Query: 137 AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGL 196
+ +T+ + + + S S E I V + D+ Y C AEN G
Sbjct: 4285 GIPLPKLTWTFNNNIIPAHFDSVNGHS---ELVIERVSKEDSGTYVCTAENSVG-----F 4336
Query: 197 VSITVRIPVSRPILMLRAPRAQAAVEDV---LELHCEALRGSPPILYWFYHE-DITLGSR 252
V + V P + + +E + L+CE P + W DI + R
Sbjct: 4337 VKAIGFVYVKEPPVF-KGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR 4395
Query: 253 SAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
G G+ E +G+Y+C A N G +RS ++TL
Sbjct: 4396 IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL 4436
Score = 41.6 bits (96), Expect = 0.001
Identities = 63/251 (25%), Positives = 100/251 (39%), Gaps = 29/251 (11%)
Query: 80 DTGSYWCEAQTMASKVLRSRRSQINVHRVPV-----ADVSLETQPPGGQVMEGDRLVLIC 134
D G Y C A A + + + ++V PV ADVS+E G + L C
Sbjct: 766 DAGDYTCVAINEAGRA--TGKITLDVGSPPVFIQEPADVSMEI---------GSNVTLPC 814
Query: 135 SVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
V G + T W + + ++ S +Q A + I ++ SD Y C AEN
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF-ILNLWASDKGTYICEAENQ 872
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
+G S ++TV V+ P++ + A L L C L G+P P W + +
Sbjct: 873 FGKIQSE-TTVTVTGLVA-PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAM 930
Query: 248 TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
L + S ++ + + G Y+C A+N G + +PT +
Sbjct: 931 LLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL 990
Query: 307 SGVIEGLLSTL 317
S IEG+ TL
Sbjct: 991 S-TIEGIPVTL 1000
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/180 (25%), Positives = 71/180 (39%), Gaps = 11/180 (6%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
S KLQIA D+G+Y C A M K + I +VP + E P V+
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI---QVPPSVAGAEI-PSDVSVL 3259
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQR----SLTAEYEIPSVRESDAEQY 181
G+ + L+C+ A G W K + +T+R + + I SD +Y
Sbjct: 3260 LGENVELVCN-ANGIPTPLIQWLKDGKPI-ASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
CVA N G + ++ V + + A + V+ + + C A PP + W
Sbjct: 3318 TCVATNPAG-EEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376
Score = 40.4 bits (93), Expect = 0.003
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 28/239 (11%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI D G Y C A+ A + +NVH VP + + +++ V+ + +
Sbjct: 2928 LQILNTQITDIGRYVCVAENTAGSA--KKYFNLNVH-VPPSVIGPKSE--NLTVVVNNFI 2982
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQ-----RSLTAEYEIPSVRESDAEQYYCVA 185
L C V+ G W K + L + T R+L +I + SD +Y C+A
Sbjct: 2983 SLTCEVS-GFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL----QIIRAKVSDGGEYTCIA 3037
Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE-----LHCEALRGSPPILY 240
N G S S+TV +P S + +V +V E L CE+ PP++
Sbjct: 3038 INQAGESKKKF-SLTVYVPPS----IKDHDSESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 241 WFYH-EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
W+ + IT + G ++ E +G Y C A N G + + LN VP
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG-RDDKNFHLNVYVP 3150
Score = 40.4 bits (93), Expect = 0.003
Identities = 52/224 (23%), Positives = 84/224 (37%), Gaps = 19/224 (8%)
Query: 80 DTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
DT +Y C A +A K R +NV +++ P ++ VL C +A G
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV------PPNIKGGPQSLVILLNKSTVLEC-IAEG 3738
Query: 140 TGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
W K GAV ++ I S +D +Y C+A N G + +
Sbjct: 3739 VPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAG-TDRRRID 3797
Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDV-LELHCEALRGSPPILYWFYHEDITLGSRSAPS- 256
+ V +P S + P + +V L CEA P + W + + ++ S
Sbjct: 3798 LQVHVPPS----IAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSY 3853
Query: 257 ---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
G+ +S + + + Y C NG G + V L VP
Sbjct: 3854 RLLSSGSLVIISPSVDDTATYECTVTNGAGDDK-RTVDLTVQVP 3896
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/155 (27%), Positives = 61/155 (39%), Gaps = 15/155 (9%)
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
+ S + SD +Y CVA N G + + V +P P +M + +EL C
Sbjct: 2070 LTSAQISDTGRYTCVAVNAAGEKQRD-IDLRVYVP---PNIMGEEQNVSVLISQAVELLC 2125
Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE------EHSGNYSCEANNGLG 283
++ PP L W L G S N S+ + + +G Y+CEA N G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKK----PGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Query: 284 AQRSEAVTLNFTVPTGARSNHLTS-GVIEGLLSTL 317
+ P S+ LT VIEG L +L
Sbjct: 2182 KTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISL 2216
Score = 39.3 bits (90), Expect = 0.007
Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 13/231 (5%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ+ ED+G Y C A A +V S+ + V P + S E + V+ + L
Sbjct: 3491 LQLLKAETEDSGKYTCIASNEAGEV--SKHFILKVLEPPHINGSEEHEEI--SVIVNNPL 3546
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE-YEIPSVRESDAEQYYCVAENGY 189
L C +A G W K L + Q E I + + D +Y C+A +
Sbjct: 3547 ELTC-IASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVED-VLELHCEALRGSPPILYWFYH-EDI 247
G VR+ V I PR + + + L C++ PP++ W + E +
Sbjct: 3606 GDDDK---EYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL 3662
Query: 248 TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
R GG ++ + + NY+C A+N G E + L VP
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFI-LTVNVP 3712
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/147 (25%), Positives = 56/147 (38%), Gaps = 19/147 (12%)
Query: 59 RALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
R LG G L I ED G Y C A A V RS + + P+ + +
Sbjct: 4397 RQLGNG-----SLAIYGTVNEDAGDYTCVATNEAGVVERSM--SLTLQSPPI----ITLE 4445
Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
P + G +++L C A G T W + ++ + I ++ D
Sbjct: 4446 PVETVINAGGKIILNCQ-ATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDT 4504
Query: 179 EQYYCVAENGYGPSPSGLVSITVRIPV 205
++ CVA N G S+ VR+PV
Sbjct: 4505 SEFECVARNLMG-------SVLVRVPV 4524
Score = 38.5 bits (88), Expect = 0.012
Identities = 63/257 (24%), Positives = 95/257 (36%), Gaps = 29/257 (11%)
Query: 63 PGWSSSPK---LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
PG S S L+I +DTG Y CEA +A K + +N+ P ++ +
Sbjct: 2148 PGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKT--EKNYNVNIWVPP--NIGGSDEL 2203
Query: 120 PGGQVMEGDRLVLICSVAMGTGDITFLW-YKGAVGLNLQSKTQRSLTA--EYEIPSVRES 176
V+EG+ + L+C + G +W KG+ L R L+ + +I +S
Sbjct: 2204 TQLTVIEGNLISLLCE-SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 177 DAEQYYCVAENGYGPSPSG-----LVSITVRIPVSRP--ILMLRAPRAQAAVEDVLELHC 229
DA Y CVA N G + + T+ S P I++ R + L C
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS--------ISLEC 2314
Query: 230 EALRGSPPILYWFY--HEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
E PP + W H I G ++ +G Y C A N G
Sbjct: 2315 EVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTD 2373
Query: 288 EAVTLNFTVPTGARSNH 304
+ L+ P NH
Sbjct: 2374 KKYDLSVHAPPSIIGNH 2390
Score = 37.0 bits (84), Expect = 0.034
Identities = 56/228 (24%), Positives = 82/228 (35%), Gaps = 24/228 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME---- 126
L I D G Y C A +A + ++I +H V + +PP +
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAG----TDETEITLHVQEPPTVE-DLEPPYNTTFQERVA 1280
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE----YEIPSVRESDAEQYY 182
R+ C A GT T W G L + E I SV D +Y
Sbjct: 1281 NQRIEFPCP-AKGTPKPTIKWLHN--GRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAV--EDVLELHCEALRGSPPILY 240
CVA N G + ++ V +P P++ + +V + L CE PI+
Sbjct: 1338 CVAVNEAGTTERKY-NLKVHVP---PVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 241 WFYHE-DITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQR 286
W+ +T S G L T E +G YSC+A N G +
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441
Score = 36.6 bits (83), Expect = 0.045
Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 19/227 (8%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
S L++ ED G Y C + A + + + V V + +LE +V
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV----KVK 2492
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYY 182
E + L C V G W+K G LQ + + +I +V+ +Y
Sbjct: 2493 EKQSVTLTCEVT-GNPVPEITWHKD--GQPLQEDEAHHIISGGRFLQITNVQVPHTGRYT 2549
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE----LHCEALRGSPPI 238
C+A + G S ++ + VS I + + V +L L CEA P
Sbjct: 2550 CLASSPAGHKSR---SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPAT 2606
Query: 239 LYWFYHEDITLGSRSAP--SGGGASFNLSLTEEHSGNYSCEANNGLG 283
+ WF +R+ GG L+ E+++G YSC A N G
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 33.9 bits (76), Expect = 0.29
Identities = 51/219 (23%), Positives = 86/219 (39%), Gaps = 14/219 (6%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
KL+I + + D G Y C A ++A + + + +++V P + ET VM +
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGE--KEIKYEVDVLVPPAIEGGDETS--YFIVMVNNL 1751
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENG 188
L L C V G+ T +W K ++ + + L + I + S+ Y C+A N
Sbjct: 1752 LELDCHVT-GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANT 1810
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWFYHE-- 245
G +TV +P P + + V+ + L C A P + W +
Sbjct: 1811 AGDHKKEF-EVTVHVP---PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 246 -DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
+ G+ S G E +G Y+C A N G
Sbjct: 1867 VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAG 1905
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 58.5 bits (140), Expect = 1e-08
Identities = 67/273 (24%), Positives = 110/273 (40%), Gaps = 40/273 (14%)
Query: 65 WSSSPKLQIAAMWKE------------DTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD 112
W+S P++++ E D G Y C QT + + + VH VP
Sbjct: 79 WTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPY--TTQVYLIVH-VPARI 135
Query: 113 VSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPS 172
V++ + V EG + L+C +A+G + T W + G + + EI
Sbjct: 136 VNISSPVT---VNEGGNVNLLC-LAVGRPEPTVTWRQLRDGFTSEGEI-------LEISD 184
Query: 173 VRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
++ A +Y CV NG +P S V + V+ P + A+ A+ L CEA+
Sbjct: 185 IQRGQAGEYECVTHNGVNSAPD---SRRVLVTVNYPPTITDVTSARTALGRAALLRCEAM 241
Query: 233 RGSPPILYWFYHEDITLGSRSAPS-------GGGASFNLSLTEEHSGNYSCEANNGLGAQ 285
PP + +Y +D L S +A +++ H GNY+C A N LGA
Sbjct: 242 -AVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGA- 299
Query: 286 RSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLG 318
+ ++ P ++ + LLS LG
Sbjct: 300 --SSASMRLLRPGSLENSAPRPPGLLALLSALG 330
Score = 38.5 bits (88), Expect = 0.012
Identities = 48/191 (25%), Positives = 71/191 (37%), Gaps = 28/191 (14%)
Query: 16 PAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-LQIA 74
PA + I+SP EG V L C + R L G++S + L+I+
Sbjct: 132 PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW--------RQLRDGFTSEGEILEIS 183
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLI 133
+ + G Y C + SRR + V+ P + DV+ G R L+
Sbjct: 184 DIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALG-------RAALL 236
Query: 134 CSVAMGTGDITFLWYKG--------AVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
AM F WYK A GL +Q++ RS+ +V Y C A
Sbjct: 237 RCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLL---FANVSARHYGNYTCRA 293
Query: 186 ENGYGPSPSGL 196
N G S + +
Sbjct: 294 ANRLGASSASM 304
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 57.8 bits (138), Expect = 2e-08
Identities = 76/324 (23%), Positives = 123/324 (37%), Gaps = 32/324 (9%)
Query: 68 SPKLQIA---------AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
SP+LQ++ ++ + DTG Y CE Q S + RS V +
Sbjct: 188 SPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVS----ANRSDPVTLNVTYGPDTPTIS 243
Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
P G L L C A + W L + T + T E IP++ +++
Sbjct: 244 PSDTYYRPGANLSLSCYAASNP-PAQYSW--------LINGTFQQSTQELFIPNITVNNS 294
Query: 179 EQYYCVAEN---GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGS 235
Y C A N G + + +T PV + + +D + L C
Sbjct: 295 GSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTG 354
Query: 236 PPILYWFYHEDITLGSRSAPSGGGASFNLS-LTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
I ++F ++ + R S G + +++ + E +G Y CE N + +S+ + LN
Sbjct: 355 ISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNV 414
Query: 295 TVPTGARSNHLTSGVIEGLLSTLGPATVAL----LFCYGLKRKIGRRS-ARDPLRSLPSP 349
+ N L+ G I G++ + A VAL L C+ K GR S RD PS
Sbjct: 415 NYNALPQENGLSPGAIAGIVIGV-VALVALIAVALACFLHFGKTGRASDQRDLTEHKPSV 473
Query: 350 LPQEFTYLNSPTPGQLQPIYENVN 373
+ N P + Y +N
Sbjct: 474 SNHTQDHSNDPPNKMNEVTYSTLN 497
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 222 EDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANN 280
+D + CE L+W ++ + + R S G + L S+T +G Y CE N
Sbjct: 160 KDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQN 219
Query: 281 GLGAQRSEAVTLNFT 295
+ A RS+ VTLN T
Sbjct: 220 PVSANRSDPVTLNVT 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,898,909
Number of Sequences: 37866
Number of extensions: 873956
Number of successful extensions: 3866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 2569
Number of HSP's gapped (non-prelim): 1082
length of query: 429
length of database: 18,247,518
effective HSP length: 105
effective length of query: 324
effective length of database: 14,271,588
effective search space: 4623994512
effective search space used: 4623994512
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.