Guide to the Human Genome
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Search of human proteins with 16418419

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo
sapiens]
         (429 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]     865   0.0  
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]    859   0.0  
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]    657   0.0  
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]               436   e-122
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]               344   8e-95
gi|157694526 Fc receptor-like 5 [Homo sapiens]                        240   2e-63
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]               179   6e-45
gi|157057547 Fc receptor-like 6 [Homo sapiens]                        119   4e-27
gi|15147240 brother of CDO [Homo sapiens]                              68   2e-11
gi|157168355 CD22 molecule [Homo sapiens]                              64   3e-10
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         64   3e-10
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    64   3e-10
gi|13489095 sialoadhesin precursor [Homo sapiens]                      63   6e-10
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho...    62   1e-09
gi|110349719 titin isoform N2-A [Homo sapiens]                         62   1e-09
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho...    62   1e-09
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [...    62   1e-09
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [...    62   1e-09
gi|156564390 carcinoembryonic antigen-related cell adhesion mole...    62   1e-09
gi|156564388 carcinoembryonic antigen-related cell adhesion mole...    62   1e-09
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    61   2e-09
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    61   2e-09
gi|224994173 roundabout 1 isoform d [Homo sapiens]                     60   5e-09
gi|224994171 roundabout 1 isoform c [Homo sapiens]                     60   5e-09
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             60   5e-09
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ...    60   5e-09
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ...    60   5e-09
gi|118572606 hemicentin 1 [Homo sapiens]                               59   8e-09
gi|157819143 IgLON family member 5 [Homo sapiens]                      59   1e-08
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...    58   2e-08

>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
          Length = 429

 Score =  865 bits (2235), Expect = 0.0
 Identities = 429/429 (100%), Positives = 429/429 (100%)

Query: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
           MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60

Query: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
           LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120

Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
           GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180

Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
           YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240

Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
           WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300

Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
           RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360

Query: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI 420
           TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI 420

Query: 421 TDVDYEDAM 429
           TDVDYEDAM
Sbjct: 421 TDVDYEDAM 429


>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
          Length = 428

 Score =  859 bits (2219), Expect = 0.0
 Identities = 428/429 (99%), Positives = 428/429 (99%), Gaps = 1/429 (0%)

Query: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
           MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60

Query: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
           LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120

Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
           GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180

Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
           YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240

Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
           WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300

Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
           RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360

Query: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANI 420
           TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESV AETLGTHMEDKVSLDIYSRLRKANI
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESV-AETLGTHMEDKVSLDIYSRLRKANI 419

Query: 421 TDVDYEDAM 429
           TDVDYEDAM
Sbjct: 420 TDVDYEDAM 428


>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
          Length = 366

 Score =  657 bits (1696), Expect = 0.0
 Identities = 337/406 (83%), Positives = 342/406 (84%), Gaps = 55/406 (13%)

Query: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
           MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60

Query: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
           LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120

Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
           GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180

Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
           YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240

Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
           WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT     
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT----- 295

Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
                                             GRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 296 ----------------------------------GRRSARDPLRSLPSPLPQEFTYLNSP 321

Query: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDK 406
           TPGQLQPIYE                N+P ++SVA      H  ++
Sbjct: 322 TPGQLQPIYE----------------NEPREQSVAVHGRQQHSSEQ 351


>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
          Length = 508

 Score =  436 bits (1122), Expect = e-122
 Identities = 234/403 (58%), Positives = 293/403 (72%), Gaps = 10/403 (2%)

Query: 21  LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
           L AS   P EG PV+L C+     Q  D Q QFCFFR+ + LG GWSSSP+LQI+A+W E
Sbjct: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170

Query: 80  DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
           DTGSYWC+A+T+  ++ + S +SQI+V R+P+++VSLE + PGGQV EG +L+L+CSVA 
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230

Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
           GTG++TF WY+ A G ++  KTQRSL+AE EIP+V+ESDA +YYC A+NG+ P  S +V+
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290

Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
           I VRIPVSRP+L LR+P AQAAV D+LELHCEALRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 291 IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350

Query: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLG 318
           GASFNLSLT EHSGNYSCEANNGLGAQ SEAV ++ + P G R + +T+GV+ GL   LG
Sbjct: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLG 410

Query: 319 PATVALLFCYGLKRKI-GRRSARDPLRSLPSPLPQEFTYLNSPTPG--QLQPIYENVNVV 375
              VALL  Y L  KI G  SA +  R    P PQEFTY +SPTP   +LQP+Y NV  V
Sbjct: 411 FTGVALLL-YALFHKISGESSATNEPRGASRPNPQEFTY-SSPTPDMEELQPVYVNVGSV 468

Query: 376 SGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKA 418
             D VYS  +  Q  + S    TL   +E+K S  IYS ++K+
Sbjct: 469 DVDVVYSQVWSMQQPESSANIRTL---LENKDSQVIYSSVKKS 508



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 72/306 (23%), Positives = 122/306 (39%), Gaps = 19/306 (6%)

Query: 1   MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
           ML   LL+I   + E A+   + +PS   EG  + L C+    Q+   Q +  + +D + 
Sbjct: 1   MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGE--QNWKIQ-KMAYHKDNKE 57

Query: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
           L      S  L I +    D+G+Y+C   T     L  + S I   +V            
Sbjct: 58  LSVFKKFSDFL-IQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114

Query: 121 GGQVMEGDRLVLICSVAMGTG----DITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
             Q +EG  + L C   +        + F +++     N    +  S + E +I +V   
Sbjct: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRE----NQVLGSGWSSSPELQISAVWSE 170

Query: 177 DAEQYYCVAENGYGPSPSGLVSITV---RIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
           D   Y+C AE          +   +   RIP+S   L +RAP  Q      L L C    
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230

Query: 234 GSPPILYWFYHE--DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
           G+  + + +Y E    ++G ++  S        ++ E  +G Y C A+NG    +S+ V 
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290

Query: 292 LNFTVP 297
           +   +P
Sbjct: 291 IPVRIP 296


>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
          Length = 734

 Score =  344 bits (883), Expect = 8e-95
 Identities = 172/279 (61%), Positives = 209/279 (74%), Gaps = 2/279 (0%)

Query: 21  LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
           L AS S P EGSP+TLTC+     Q  D Q QF  FRD++ LG GWS SP+LQI AMW E
Sbjct: 194 LRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTE 253

Query: 80  DTGSYWCEAQTMASKVL-RSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
           D+GSYWCE +T+   +  RS RSQI V RVPV++V+LE +P GGQ++EG+ +VLICSVA 
Sbjct: 254 DSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ 313

Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
           G+G +TF W+K     +L  KTQRSL AE  + +V+ESDA +YYC A+N + P  S  + 
Sbjct: 314 GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIR 373

Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
           +TVRIPVS P+L  RAPRA   V D+LELHCE+LRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 374 VTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGG 433

Query: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
           GASFNLSLT EHSGNYSC+A+NGLGAQ S  V+L  TVP
Sbjct: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVP 472



 Score =  231 bits (589), Expect = 1e-60
 Identities = 166/415 (40%), Positives = 220/415 (53%), Gaps = 35/415 (8%)

Query: 30  EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSS--PKLQIAAMWKEDTGSYWCE 87
           EG  + L C +    S    F +      R+LG     S   +L +  + + D G Y+C 
Sbjct: 301 EGENMVLICSVA-QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCA 359

Query: 88  AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
           A  + S +L S   ++ V R+PV+   L  + P    + GD L L C    G+  I + +
Sbjct: 360 ADNVHSPIL-STWIRVTV-RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRF 417

Query: 148 YKGAVGLNLQSKTQR-------SLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
           Y   V L   S           SLTAE+         +  Y C A+NG G   S  VS+ 
Sbjct: 418 YHEDVTLGNSSAPSGGGASFNLSLTAEH---------SGNYSCDADNGLGAQHSHGVSLR 468

Query: 201 VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGA 260
           V +PVSRP+L LRAP AQA V D+LELHCE+LRGS PILYWFYHED TLG+ SA SGGGA
Sbjct: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528

Query: 261 SFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPA 320
           SFNLSLT EHSGNYSCEA+NGLGAQ S+ VTLN T  +  R+    +G+   +LS L  A
Sbjct: 529 SFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLA 588

Query: 321 TVALLFCYG-LKRKIGRRSA-----------RDPLRSLPSPL-PQEFTYLNSPTPGQLQP 367
             A L  Y   +RK G  SA           ++P  S PS + PQE T+     P +L+P
Sbjct: 589 AAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEP 648

Query: 368 IYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANITD 422
           +Y NVN    + +YS  +  Q  +E+ +A     H E +    +YS L+K +  D
Sbjct: 649 MYSNVNPGDSNPIYSQIWSIQHTKEN-SANCPMMHQEHEELTVLYSELKKTHPDD 702


>gi|157694526 Fc receptor-like 5 [Homo sapiens]
          Length = 977

 Score =  240 bits (613), Expect = 2e-63
 Identities = 170/420 (40%), Positives = 226/420 (53%), Gaps = 22/420 (5%)

Query: 7   LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP--- 63
           L +  P+  P  L L    +    G  + L C+ P          + F+ +   LG    
Sbjct: 557 LFVTVPVSRPI-LTLRVPRAQAVVGDLLELHCEAP---RGSPPILYWFYHEDVTLGSSSA 612

Query: 64  --GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHR-VPVADVSLETQPP 120
             G  +S  L + A   E +G+Y CEA    + ++      I++   VPV+   L  + P
Sbjct: 613 PSGGEASFNLSLTA---EHSGNYSCEAN---NGLVAQHSDTISLSVIVPVSRPILTFRAP 666

Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
             Q + GD L L C    G+  I + +Y   V L   S       A + + S+    +  
Sbjct: 667 RAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG-GASFNL-SLTTEHSGI 724

Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
           Y C A+NG     S +V++ V +PVSRP+L LRAP   AAV D+LELHCEALRGSP ILY
Sbjct: 725 YSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILY 784

Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
            F+HED+TLG+RS+PSGG AS NLSLT EHSGNYSCEA+NGLGAQRSE VTL  T  T  
Sbjct: 785 RFFHEDVTLGNRSSPSGG-ASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTAN 843

Query: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
           RS    +GV  GLLS  G A  ALL    L RK GR+ A DP RS      QE TY N P
Sbjct: 844 RSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVP 903

Query: 361 TPGQLQPIYENVNVVSGDEVYS-LAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKAN 419
              +LQP+Y N N    + VYS +    + ++ +VA++    H+ +K S  IYS ++ A+
Sbjct: 904 AWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDP--RHLRNKGSPIIYSEVKVAS 961



 Score =  211 bits (538), Expect = 8e-55
 Identities = 122/280 (43%), Positives = 161/280 (57%), Gaps = 7/280 (2%)

Query: 21  LIASPSHPTEGSPVTLTCKMPF-LQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
           L AS   P  G+PVTLTC+    L+ SD   +F FFRD + LG GWS SP  QI AMW +
Sbjct: 194 LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSK 253

Query: 80  DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
           D+G YWC+A TM   V+  S RS I V ++P +   L   P      EG ++ L C    
Sbjct: 254 DSGFYWCKAATMPYSVISDSPRSWIQV-QIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312

Query: 139 GTGDITFLWYKGAVGLNLQS-KTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
            +    + +Y   V L  +S + +R  +  +   S+   ++  YYC A+NG G  PS  V
Sbjct: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISF---SLTTENSGNYYCTADNGLGAKPSKAV 369

Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
           S++V +PVS P+L L +P         + LHCEA RGS PILY F+HE   L  RSA S 
Sbjct: 370 SLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA 429

Query: 258 GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
           GG + + SLT EHSGNY C A+NG G QRS+AV+L+ TVP
Sbjct: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVP 469



 Score =  203 bits (516), Expect = 3e-52
 Identities = 124/270 (45%), Positives = 161/270 (59%), Gaps = 9/270 (3%)

Query: 30  EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-GWSSSPKLQIA-AMWKEDTGSYWCE 87
           EG+ VTL C+    Q       + F  +  AL     +S+  + I+ ++  E +G+Y+C 
Sbjct: 393 EGAKVTLHCEA---QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCT 449

Query: 88  AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
           A        RS+   ++V  VPV+   L          EG  + L C V  G+  I + +
Sbjct: 450 ADNGFGPQ-RSKAVSLSV-TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQF 507

Query: 148 YKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
           Y     + L S +  S+       S+ E  +  YYC A+NG+GP  S +VS+ V +PVSR
Sbjct: 508 YHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565

Query: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
           PIL LR PRAQA V D+LELHCEA RGSPPILYWFYHED+TLGS SAPSGG ASFNLSLT
Sbjct: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT 625

Query: 268 EEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
            EHSGNYSCEANNGL AQ S+ ++L+  VP
Sbjct: 626 AEHSGNYSCEANNGLVAQHSDTISLSVIVP 655



 Score =  198 bits (503), Expect = 9e-51
 Identities = 130/296 (43%), Positives = 168/296 (56%), Gaps = 16/296 (5%)

Query: 7   LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
           L +  P+  P  L L ++ +   EG+ VTL C++   Q    Q  + F+ +   L   WS
Sbjct: 464 LSVTVPVSHPV-LTLSSAEALTFEGATVTLHCEV---QRGSPQILYQFYHEDMPL---WS 516

Query: 67  SSP----KLQIA-AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
           SS     ++  + ++ +  +G+Y+C A        RS    + V  VPV+   L  + P 
Sbjct: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ-RSEVVSLFV-TVPVSRPILTLRVPR 574

Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
            Q + GD L L C    G+  I + +Y   V L   S       A + + S+    +  Y
Sbjct: 575 AQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGG-EASFNL-SLTAEHSGNY 632

Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
            C A NG     S  +S++V +PVSRPIL  RAPRAQA V D+LELHCEALRGS PILYW
Sbjct: 633 SCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692

Query: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
           FYHED+TLG  SAPSGGGASFNLSLT EHSG YSCEA+NGL AQRSE VTL   VP
Sbjct: 693 FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVP 748



 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 90/326 (27%), Positives = 140/326 (42%), Gaps = 35/326 (10%)

Query: 11  APLCEPAEL------FLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG 64
           +PL  P  L       ++ +P    EG  V L C+      ++       +++   L   
Sbjct: 90  SPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA----KAEVTLNNTIYKNDNVLA-F 144

Query: 65  WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
            +      I     +D G+Y C     +   + S   +I V       V    +    Q 
Sbjct: 145 LNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPV---LRASSFQP 201

Query: 125 MEGDRLVLIC----SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
           + G+ + L C    S+      + F +++    L L      SL+  ++I ++   D+  
Sbjct: 202 ISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW----SLSPNFQITAMWSKDSGF 257

Query: 181 YYCVAENGYGPSPSGLVS------ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
           Y+C A       P  ++S      I V+IP S P+L L   +A       + LHCE    
Sbjct: 258 YWCKAAT----MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQED 313

Query: 235 SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
           S   LY FYHE + L  +S     GAS + SLT E+SGNY C A+NGLGA+ S+AV+L+ 
Sbjct: 314 SLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSV 373

Query: 295 TVPTGARSNHLTSG---VIEGLLSTL 317
           TVP      +L+S    + EG   TL
Sbjct: 374 TVPVSHPVLNLSSPEDLIFEGAKVTL 399



 Score = 29.3 bits (64), Expect = 7.2
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 16/114 (14%)

Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESD 177
           QPP   V +G+R+ L C            WY   +G  +  +T  +      I  V+ES 
Sbjct: 28  QPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDN------ILEVQESG 81

Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEA 231
             +Y C A+     SP       V +  S   L+L+AP +    + V+ L C A
Sbjct: 82  --EYRCQAQGSPLSSP-------VHLDFSSASLILQAPLSVFEGDSVV-LRCRA 125


>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
          Length = 515

 Score =  179 bits (453), Expect = 6e-45
 Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 2/184 (1%)

Query: 21  LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
           L A+ S PTEG+ V L+C+     + SD    F FFRD   +   WS+ P+LQ+  +W+E
Sbjct: 195 LKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRE 254

Query: 80  DTGSYWCEAQTMASKVLRSRRS-QINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
           ++GSYWC A+T+   + +   S QI+V R+PV+ V LETQP GGQ +EG+ LVL+CSVA 
Sbjct: 255 NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314

Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
           GTGD TF W++  +  +L  KTQRSL AE E+P++R+S A  YYC A+N YGP  S +++
Sbjct: 315 GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374

Query: 199 ITVR 202
           +TVR
Sbjct: 375 VTVR 378



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 79/256 (30%), Positives = 123/256 (48%), Gaps = 9/256 (3%)

Query: 167 EYEIPSVRESDAEQYYCVAE----NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE 222
           E ++P+V   ++  Y+C AE    N +  SPS  + +  RIPVS  +L  +    QA   
Sbjct: 245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ-RIPVSGVLLETQPSGGQAVEG 303

Query: 223 DVLELHCEALRGSPPILYWFYHEDI--TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANN 280
           ++L L C    G+    + ++ ED+  +LG ++  S        ++ + H+G Y C A+N
Sbjct: 304 EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADN 363

Query: 281 GLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSAR 340
             G  +S  + +      G R   + +G   GLLS L  A VALLF    +RK G     
Sbjct: 364 SYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLA-VALLFHCWRRRKSGVGFLG 422

Query: 341 DPLRSLPSPLPQEFTYLNSPTPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLG 400
           D  R  P+P P E ++   P   +LQ +Y +V+   GD VYS     Q  +E   A T  
Sbjct: 423 DETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEE-EANTSR 481

Query: 401 THMEDKVSLDIYSRLR 416
           T +EDK    +YS ++
Sbjct: 482 TLLEDKDVSVVYSEVK 497


>gi|157057547 Fc receptor-like 6 [Homo sapiens]
          Length = 434

 Score =  119 bits (299), Expect = 4e-27
 Identities = 117/393 (29%), Positives = 176/393 (44%), Gaps = 39/393 (9%)

Query: 19  LFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWK 78
           L+L A P+   EG  +TL C+      +    Q  F+RD + L      +  L + A   
Sbjct: 20  LYLQAWPNPVFEGDALTLRCQG---WKNTPLSQVKFYRDGKFLHFS-KENQTLSMGAATV 75

Query: 79  EDTGSYWCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLICSVA 137
           +  G Y C  Q M      ++ S+  + +V  +    + +  P  +  EG  + L C   
Sbjct: 76  QSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTK 135

Query: 138 M----GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC--VAENGYGP 191
           +        + F ++K   G  LQ    R    E  IP  +E D+  Y+C    E G   
Sbjct: 136 LHPLRSALRLLFSFHKD--GHTLQD---RGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQ 190

Query: 192 SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGS 251
             S  + + V+ PVSRP+L L    A  AV D+++L CEA RGSPPILY FY ++  +G+
Sbjct: 191 KQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGN 250

Query: 252 RSAPSGGGASFNLSL-TEEHSGNYSCEANNGLGAQRSEAVTLNF---TVPTGARSNHLTS 307
            SAP GG  S    + +E+ +GNYSCEA N +  +RSE   L+     V     SN L  
Sbjct: 251 HSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVP 310

Query: 308 GVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQP 367
            +   LL  +  A   L++     RK G          LPS +P       +   G+  P
Sbjct: 311 WLPASLLGLMVIAAALLVYVRSW-RKAG---------PLPSQIPP------TAPGGEQCP 354

Query: 368 IYENVNVVSGDE---VYSLAYYNQPEQESVAAE 397
           +Y NV+   G +   VYS+ +      E+ +AE
Sbjct: 355 LYANVHHQKGKDEGVVYSVVHRTSKRSEARSAE 387


>gi|15147240 brother of CDO [Homo sapiens]
          Length = 1114

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 69/266 (25%), Positives = 110/266 (41%), Gaps = 19/266 (7%)

Query: 30  EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG---WSSSPKLQIAAMWKEDTGSYWC 86
           EG+   + C +P      AQ ++   ++      G      S  LQI    +ED G Y C
Sbjct: 142 EGNTAVIACHLPESHPK-AQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKC 200

Query: 87  EAQTMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQ---VMEGDRLVLICSVAMGTGD 142
            A    ++ +++  S   +  R   A+ +    PP  Q   V +G  L+L C VA G   
Sbjct: 201 AAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILEC-VASGIPP 259

Query: 143 ITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVR 202
               W K    +   +KT R L +   I +  E D+  Y C+A+NG G   + ++   V+
Sbjct: 260 PRVTWAKDGSSVTGYNKT-RFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQ 318

Query: 203 I----PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
           +     V+  +  L  P  Q+A     +L CE     PP + W  +    + S+      
Sbjct: 319 VFEPPEVTMELSQLVIPWGQSA-----KLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSR 373

Query: 259 GASFNLSLTEEHSGNYSCEANNGLGA 284
            A   LS+  E  G Y C A N +G+
Sbjct: 374 RALRVLSMGPEDEGVYQCMAENEVGS 399



 Score = 32.7 bits (73), Expect = 0.65
 Identities = 54/238 (22%), Positives = 82/238 (34%), Gaps = 21/238 (8%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L I A+     G Y C A+  A  V     +   V    + D  L+ Q    +V EG+  
Sbjct: 91  LVITALNNHTVGRYQCVARMPAGAVASVPAT---VTLANLQDFKLDVQHVI-EVDEGNTA 146

Query: 131 VLICSV------AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
           V+ C +      A     +   W + + G  L   +        +I +  + D   Y C 
Sbjct: 147 VIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPS-----GNLQIVNASQEDEGMYKCA 201

Query: 185 AENGYGPSPSGLVS---ITVRIPVSRPILMLRAPRAQAAVE---DVLELHCEALRGSPPI 238
           A N          S   + VR   +    ++  P AQ  +      L L C A    PP 
Sbjct: 202 AYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPR 261

Query: 239 LYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
           + W        G              + +EE SG Y C A+NG+G   +  +  N  V
Sbjct: 262 VTWAKDGSSVTGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQV 319


>gi|157168355 CD22 molecule [Homo sapiens]
          Length = 847

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 70/301 (23%), Positives = 106/301 (35%), Gaps = 52/301 (17%)

Query: 22  IASPSHPTEGSPVTLTCKMPF----------------------LQSSDAQFQFCFFRDTR 59
           I  P    E   VTLTC + F                      + S+    +  F R   
Sbjct: 145 IQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEGVPMRQAAVTSTSLTIKSVFTRSEL 204

Query: 60  ALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
              P WS   K+              C+ Q    K L +   Q+NV   P  ++ +   P
Sbjct: 205 KFSPQWSHHGKIVT------------CQLQDADGKFLSNDTVQLNVKHTPKLEIKVT--P 250

Query: 120 PGGQVMEGDRLVLICSVAMGTGDITFL-WYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
               V EGD + + C V+    + T + W K    L  Q+      T    +  V +  +
Sbjct: 251 SDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQN------TFTLNLREVTKDQS 304

Query: 179 EQYYCVAENGYGPSPSGLVSITVRI-PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
            +Y C   N  GP  S  V + V+  P    + +L +P  + +  + L   C +L    P
Sbjct: 305 GKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEGSQVEFL---CMSLANPLP 361

Query: 238 ILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTLNFTV 296
             Y +YH    +  R+            +   H+G YSC A N LG  QR     L+   
Sbjct: 362 TNYTWYHNGKEMQGRTEEK----VHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQY 417

Query: 297 P 297
           P
Sbjct: 418 P 418



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/282 (22%), Positives = 106/282 (37%), Gaps = 41/282 (14%)

Query: 21  LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAM---- 76
           +I +P    EG  VTL+C       S  ++++           G    P L +  +    
Sbjct: 425 VIQNPMPIREGDTVTLSCNYNSSNPSVTRYEW--------KPHGAWEEPSLGVLKIQNVG 476

Query: 77  WKEDT-----GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
           W   T      + WC   + AS V       +NV   P  DV +    P  ++  G+ + 
Sbjct: 477 WDNTTIACAACNSWC---SWASPVA------LNVQYAP-RDVRVRKIKPLSEIHSGNSVS 526

Query: 132 LICSVAMG-TGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
           L C  +     ++ F W K    L  +S        +    S+   DA  Y C   N  G
Sbjct: 527 LQCDFSSSHPKEVQFFWEKNGRLLGKES--------QLNFDSISPEDAGSYSCWVNNSIG 578

Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLG 250
            + S   ++ V +   R + +  +P  Q        L CE+   +PP+ ++ + +     
Sbjct: 579 QTASKAWTLEV-LYAPRRLRVSMSPGDQVMEGKSATLTCES-DANPPVSHYTWFD---WN 633

Query: 251 SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
           ++S P          +  +HSG Y C+  N +G  RS   TL
Sbjct: 634 NQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTL 675



 Score = 36.6 bits (83), Expect = 0.045
 Identities = 61/305 (20%), Positives = 124/305 (40%), Gaps = 24/305 (7%)

Query: 15  EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
           EP+ + ++ SP+   EGS V   C      ++     + ++ + + +     +  K+ I 
Sbjct: 332 EPSTVQILHSPA--VEGSQVEFLCMS---LANPLPTNYTWYHNGKEMQG--RTEEKVHIP 384

Query: 75  AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLIC 134
            +     G+Y C A+ +     R   ++++V   P    ++   P    + EGD + L C
Sbjct: 385 KILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPKKVTTVIQNPM--PIREGDTVTLSC 442

Query: 135 SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPS 194
           +       +T   +K           +       +I +V   D     C A N +  S +
Sbjct: 443 NYNSSNPSVTRYEWKP------HGAWEEPSLGVLKIQNVGW-DNTTIACAACNSWC-SWA 494

Query: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
             V++ V+       +    P ++    + + L C+     P  + +F+ ++  L  + +
Sbjct: 495 SPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKNGRLLGKES 554

Query: 255 PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSG--VIEG 312
                 +F+ S++ E +G+YSC  NN +G   S+A TL            ++ G  V+EG
Sbjct: 555 Q----LNFD-SISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609

Query: 313 LLSTL 317
             +TL
Sbjct: 610 KSATL 614



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 9/118 (7%)

Query: 200 TVRIPVSR-PILMLRAPRAQAAVE--DVLELHCEALRGSPPILYWFYHEDITLGSRSAPS 256
           TV++ V   P L ++   + A V   D + + CE    +P      + +D T    S   
Sbjct: 233 TVQLNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGT----SLKK 288

Query: 257 GGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNFT-VPTGARSNHLTSGVIEG 312
               + NL  +T++ SG Y C+ +N +G  RSE V L     P  +    L S  +EG
Sbjct: 289 QNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEG 346


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 73/270 (27%), Positives = 108/270 (40%), Gaps = 27/270 (10%)

Query: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
           L P  SSS KL+I A  + D G+Y C A         S   Q+ V   P       T+ P
Sbjct: 623 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL-----TELP 675

Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKG-------AVGLNLQSKTQRSLTAEYEIPSV 173
               +E  R  L+   A G    T  W +G        +G    S++++  +      SV
Sbjct: 676 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 735

Query: 174 RESDAEQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
              D   Y C A N +G       + +T   P   P +   AP  +      + L C  L
Sbjct: 736 APEDQAPYVCEARNVFGKVQAEARLIVTGHAP---PQIASSAPTVRVLEGQPVSLPCIVL 792

Query: 233 RGSP-PILYWFYH-EDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
            G P P  +W      +  GSR +    G+       +EH+G YSC A N  G+Q  + V
Sbjct: 793 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRD-V 851

Query: 291 TLNFTVPT---GARSNHLTSGVIEGLLSTL 317
            L   VP       ++H+T+   EG+ ++L
Sbjct: 852 ELVVQVPPRIHPTATHHITN---EGVPASL 878



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 66/252 (26%), Positives = 101/252 (40%), Gaps = 24/252 (9%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L I  +  ED G+Y C+A    +  + + +  + ++      VS         V  G+  
Sbjct: 545 LIIQGVAPEDAGNYSCQA----TNEVGTDQETVTLYYTDPPSVSAVNAVV--LVAVGEEA 598

Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
           VL+C  A G      +WY+G  GL +    + S + +  IP+ +E DA  Y C A N  G
Sbjct: 599 VLVCE-ASGVPPPRVIWYRG--GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 655

Query: 191 PSPSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
            +     S  +++ V     +   PR     +     L C A    PP + W   +   L
Sbjct: 656 DA-----SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 710

Query: 250 G--------SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA-VTLNFTVPTGA 300
           G        SRS     G  F  S+  E    Y CEA N  G  ++EA + +    P   
Sbjct: 711 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQI 770

Query: 301 RSNHLTSGVIEG 312
            S+  T  V+EG
Sbjct: 771 ASSAPTVRVLEG 782



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 61/263 (23%), Positives = 96/263 (36%), Gaps = 21/263 (7%)

Query: 31  GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYW 85
           G    L+C++      +A +   + RD R L          +   L+I+ +   D G Y 
Sbjct: 414 GETAVLSCRV----LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 469

Query: 86  CEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITF 145
           C A   A+ V R+    + V   P   +   +Q       +G  + + CS A G      
Sbjct: 470 CVASN-ANGVTRAS-VWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCS-ASGYPTPHI 522

Query: 146 LWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
            W + +  L   S+          I  V   DA  Y C A N  G       ++T+    
Sbjct: 523 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQE---TVTLYYTD 579

Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
              +  + A    A  E+ + L CEA    PP + W Y   + +      S  G     +
Sbjct: 580 PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIW-YRGGLEMILAPEGSSSGKLRIPA 637

Query: 266 LTEEHSGNYSCEANNGLGAQRSE 288
             E  +G Y+C A N LG   +E
Sbjct: 638 AQERDAGTYTCRAVNELGDASAE 660



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 77/299 (25%), Positives = 109/299 (36%), Gaps = 60/299 (20%)

Query: 16   PAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK----L 71
            P ++   A      EG PV+L C    + +     +  + +D R L PG   S +    L
Sbjct: 767  PPQIASSAPTVRVLEGQPVSLPC---IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSL 823

Query: 72   QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINV----HRVPVADVSLETQPPGGQVMEG 127
             +    +E  G Y C A   A    R     + V    H      ++ E  P        
Sbjct: 824  HLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPAS------ 877

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQ------SKTQRSLTAEYEIPSVRESDAEQY 181
                L C VA G    T  W K    L  +      SK    L A+   PS +  DA  Y
Sbjct: 878  ----LPC-VASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQ---PSAQ--DAGAY 927

Query: 182  YCVAENGYGPSPSGLVSITVRIPVS-RPILMLRAPR-------AQAAVEDVLELHCEALR 233
             C A N  G S     S  +R+ V+ +P + +   R         A   + + L CEA  
Sbjct: 928  VCTATNTVGFS-----SQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKG 982

Query: 234  GSPPILYWFYHEDITLGSRSAPS-----GGGASFNLSLTEEH---SGNYSCEANNGLGA 284
              PP++ W      T  SR  P      G   S +L L +     SG+Y C A+N  G+
Sbjct: 983  SPPPLVTW------TKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGS 1035


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 73/270 (27%), Positives = 108/270 (40%), Gaps = 27/270 (10%)

Query: 61  LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
           L P  SSS KL+I A  + D G+Y C A         S   Q+ V   P       T+ P
Sbjct: 740 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL-----TELP 792

Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKG-------AVGLNLQSKTQRSLTAEYEIPSV 173
               +E  R  L+   A G    T  W +G        +G    S++++  +      SV
Sbjct: 793 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 852

Query: 174 RESDAEQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
              D   Y C A N +G       + +T   P   P +   AP  +      + L C  L
Sbjct: 853 APEDQAPYVCEARNVFGKVQAEARLIVTGHAP---PQIASSAPTVRVLEGQPVSLPCIVL 909

Query: 233 RGSP-PILYWFYH-EDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
            G P P  +W      +  GSR +    G+       +EH+G YSC A N  G+Q  + V
Sbjct: 910 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRD-V 968

Query: 291 TLNFTVPT---GARSNHLTSGVIEGLLSTL 317
            L   VP       ++H+T+   EG+ ++L
Sbjct: 969 ELVVQVPPRIHPTATHHITN---EGVPASL 995



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 16/224 (7%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +L+IA    ED G+Y C A+  A   +   R  + V  V      +E   P     EG  
Sbjct: 4001 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 4054

Query: 130  LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
              L C  A G+ +    W K G      + K     + E  + ++   DA  Y C AEN 
Sbjct: 4055 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 4113

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
             G +   +    + +PV   +   R+ R    + D L L C A RGSP P + W  ++  
Sbjct: 4114 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 4168

Query: 248  TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
                 S   GG      +++ E SG Y C A N +G  R++AV+
Sbjct: 4169 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVS 4210



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 66/252 (26%), Positives = 101/252 (40%), Gaps = 24/252 (9%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L I  +  ED G+Y C+A    +  + + +  + ++      VS         V  G+  
Sbjct: 662 LIIQGVAPEDAGNYSCQA----TNEVGTDQETVTLYYTDPPSVSAVNAVV--LVAVGEEA 715

Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
           VL+C  A G      +WY+G  GL +    + S + +  IP+ +E DA  Y C A N  G
Sbjct: 716 VLVCE-ASGVPPPRVIWYRG--GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 772

Query: 191 PSPSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
            +     S  +++ V     +   PR     +     L C A    PP + W   +   L
Sbjct: 773 DA-----SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 827

Query: 250 G--------SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA-VTLNFTVPTGA 300
           G        SRS     G  F  S+  E    Y CEA N  G  ++EA + +    P   
Sbjct: 828 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQI 887

Query: 301 RSNHLTSGVIEG 312
            S+  T  V+EG
Sbjct: 888 ASSAPTVRVLEG 899



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 68/245 (27%), Positives = 94/245 (38%), Gaps = 25/245 (10%)

Query: 61   LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
            L       P LQ+ A+   D+G+Y C A + A +    R  Q+ V   P  + S   QP 
Sbjct: 3448 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 3503

Query: 121  GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
               +  G  + L+C  A GT      W+K    L       R+         +R  DA  
Sbjct: 3504 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 3556

Query: 181  YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
            Y C+AE     SP+G +  + R+ V  P  I+  R PR         L L C       P
Sbjct: 3557 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 3611

Query: 238  ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
             + W  H D  +    A    P  G      +L+   SG+YSC A N  G+         
Sbjct: 3612 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 3669

Query: 294  FTVPT 298
             TVPT
Sbjct: 3670 HTVPT 3674



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 61/246 (24%), Positives = 93/246 (37%), Gaps = 19/246 (7%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
            LQ AA+ +ED+G+Y C A+    +      S ++V   PV      S   +P GG +   
Sbjct: 4182 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 4237

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
                L C V  G       W K  + L       +       I      DA +Y C+AEN
Sbjct: 4238 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 4292

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G +      + + +  S P+  +          D + L C+A     P + W      
Sbjct: 4293 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 4348

Query: 248  TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
               SR   +    S  L   E   +G Y C A+N LG+  + A  +    P G+  +   
Sbjct: 4349 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS--M 4406

Query: 307  SGVIEG 312
            +GVI G
Sbjct: 4407 TGVING 4412



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)

Query: 82   GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
            G+Y CE   +      S+  Q+ VH  P   ++   +PP    +  D +  +   A G  
Sbjct: 2231 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 2286

Query: 142  DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
              T  W +        +GL LQ++ Q        +   + +   +Y CVAEN  G +   
Sbjct: 2287 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 2341

Query: 196  LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
               ++V +P      +       AA+   L L CEA+   PP + WF  E+ ++ G  + 
Sbjct: 2342 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 2400

Query: 255  PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
               GG    ++ T+E  SG YSC A+N  G  R
Sbjct: 2401 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 2433



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 65/256 (25%), Positives = 96/256 (37%), Gaps = 26/256 (10%)

Query: 65   WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
            +S  P LQI  +   D G Y C A  +A +  R    ++ V        ++E  P    V
Sbjct: 1844 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 1897

Query: 125  MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
            +E   + L C +A G       W+KG   ++       S+      I   + SDA  Y C
Sbjct: 1898 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 1956

Query: 184  VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
            VA N  G +    +   +R+ V   I +  +      V   + L C A     P L W  
Sbjct: 1957 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 2013

Query: 244  HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
                  G+  +P+G        GG    L S     SG YSC A + +G  R + V L  
Sbjct: 2014 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQV 2067

Query: 295  TVPTGARSNHLTSGVI 310
             +P       L   V+
Sbjct: 2068 HMPPSILGEELNVSVV 2083



 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 77/291 (26%), Positives = 109/291 (37%), Gaps = 37/291 (12%)

Query: 32   SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
            +PV LTC       P +  S A  Q        A G G+  SP   L+I        G Y
Sbjct: 3872 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 3925

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C A+  A   +  +   + V   PV    ++  P   + +  + ++L C  A G    T
Sbjct: 3926 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 3978

Query: 145  FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
              W K  + +     TQ     +  I      DA  Y C+A+N  G S  G   + V++P
Sbjct: 3979 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 4037

Query: 205  VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
               P++    P           L C+A RGSP P + W        G+       PSG  
Sbjct: 4038 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 4093

Query: 260  ASFNLSLTEEHSGNYSCEANNGLGAQRSEA-----VTLNFTVPTGARSNHL 305
               NL    + +G Y+C A N +G  R        V   FT   G RS  L
Sbjct: 4094 LVKNLE--GQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL 4142



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 35/240 (14%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV------ 124
            LQI    KED G Y C       + ++      N H   +   S+    P G+V      
Sbjct: 2597 LQILNAQKEDAGQYTCVVTNELGEAVK------NYHVEVLIPPSISKDDPLGEVGVKEVK 2650

Query: 125  -MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYY 182
                  L L C  +      T  WYK    +   S+ Q        +I   + SD+ +Y 
Sbjct: 2651 TKVNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 2709

Query: 183  CVAENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE-------- 226
            CVA N  G        +    P+ + +        ++ R   A+  V +  E        
Sbjct: 2710 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY 2769

Query: 227  LHCEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
            L+C+     PP L W Y ED  ++ G   +   GG    + L   E++G YSC+A+N +G
Sbjct: 2770 LYCDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 2828



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
            +P EL L       T G+P+ L C          Q    + +D +AL    ++S   ++ 
Sbjct: 3501 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 3549

Query: 75   AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
             +   D G Y C A++ A  + +S R ++      V        P G + + G    +LV
Sbjct: 3550 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 3600

Query: 132  LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
            L CSV A     IT  W++  + L   + TQ      + ++ ++  +D+  Y C A N  
Sbjct: 3601 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 3657

Query: 190  GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
                +G  S+  R+ +   P +    P    +V     L C+A     P++ W   + + 
Sbjct: 3658 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 3712

Query: 249  LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
            L  RS      P G   S  +  +  + +G+Y C A+N  G+ R
Sbjct: 3713 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 3753



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 67/249 (26%), Positives = 98/249 (39%), Gaps = 39/249 (15%)

Query: 64   GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ 123
            G   S  L++A +   D+G Y C A   A     S R  + V   P     ++  P   +
Sbjct: 1077 GLLPSGSLRLAQVQVGDSGHYECTASNPAGSA--SHRYVLGVQVPP----QVQPGPRVLK 1130

Query: 124  VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
            V+ G+ L L C VA G  +    W K  V L       R         ++R SDA +Y C
Sbjct: 1131 VLVGEALDLNC-VAEGNPEPQLSWSKDGVVLQ-----GRGPQGSVHFAAIRTSDAGRYRC 1184

Query: 184  VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVL----ELHCEALRGSP-PI 238
             A N      +G+ +  V + V  P     A      +E V      L C A RG+P P 
Sbjct: 1185 EASNS-----AGVDAWEVELRVLEPPHW-GADETSGLLERVAGENASLPCPA-RGTPKPQ 1237

Query: 239  LYWFYHEDITLGSRSAPSGG---------GASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
            + W        G  S P  G         G+ F  S++   SG+Y C+A N +G+    A
Sbjct: 1238 VTW------RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRA 1291

Query: 290  VTLNFTVPT 298
              + +  P+
Sbjct: 1292 KLVVYVPPS 1300



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 20/249 (8%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +L+I      D G Y C+   +A + +R+    +   +VP    + +T+      + G  
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV---QVPPTFENPKTETV--SQVAGSP 3141

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA---EYEIPSVRESDAEQYYCVAE 186
            LVL C V+ G    T  W K    + ++S     + +     ++  ++ + A  Y CVAE
Sbjct: 3142 LVLTCDVS-GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 3198

Query: 187  NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
            N    +    V   +  P  R   + R        E  + L CEA    PP + W   + 
Sbjct: 3199 NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQE--VRLDCEADGQPPPDVAWL-KDG 3255

Query: 247  ITLGSRSAPS-----GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
              LG    P       GG+     L    +G Y+C A+N  G + +   T+N  VP   +
Sbjct: 3256 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVPPTIK 3314

Query: 302  SNHLTSGVI 310
                 SG +
Sbjct: 3315 QGADGSGTL 3323



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +LQ+      D G Y C+A        ++ R  + V   P        +P   + + G  
Sbjct: 1557 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 1613

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
            + L C VA G    T  W+    GL +    +  L  +     + S  E+ +  Y CVA 
Sbjct: 1614 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 1670

Query: 187  NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
            +   P+   ++  +V + V   +L+     +    V   LEL C+A     P + W  + 
Sbjct: 1671 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 1727

Query: 245  ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
               E++  G + A  G   + ++   E +HSG ++C+A N  G   +E
Sbjct: 1728 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 1772



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 66/280 (23%), Positives = 105/280 (37%), Gaps = 19/280 (6%)

Query: 30   EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
            E +P  L C    +   D      ++R+ + L  G   S       LQI  +  E+ G Y
Sbjct: 2764 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 2819

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C+A     +       ++ V   PV     E       V     + L C  A+G    T
Sbjct: 2820 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 2876

Query: 145  FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
              W +  +  +   + Q     +  ++ +   +DA  Y CVAEN  G   S     T+R+
Sbjct: 2877 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 2933

Query: 204  PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
             V   I  L   +  A +   + L C+      P + W+   + ++LG       G  + 
Sbjct: 2934 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 2993

Query: 263  NLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
             L       SG Y+CEA N  G  + + V L+  VP   R
Sbjct: 2994 QLGRARLSDSGMYTCEALNAAGRDQ-KLVQLSVLVPPAFR 3032



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 61/263 (23%), Positives = 96/263 (36%), Gaps = 21/263 (7%)

Query: 31  GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYW 85
           G    L+C++      +A +   + RD R L          +   L+I+ +   D G Y 
Sbjct: 531 GETAVLSCRV----LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 586

Query: 86  CEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITF 145
           C A   A+ V R+    + V   P   +   +Q       +G  + + CS A G      
Sbjct: 587 CVASN-ANGVTRAS-VWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCS-ASGYPTPHI 639

Query: 146 LWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
            W + +  L   S+          I  V   DA  Y C A N  G       ++T+    
Sbjct: 640 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQE---TVTLYYTD 696

Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
              +  + A    A  E+ + L CEA    PP + W Y   + +      S  G     +
Sbjct: 697 PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIW-YRGGLEMILAPEGSSSGKLRIPA 754

Query: 266 LTEEHSGNYSCEANNGLGAQRSE 288
             E  +G Y+C A N LG   +E
Sbjct: 755 AQERDAGTYTCRAVNELGDASAE 777



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 63/277 (22%), Positives = 117/277 (42%), Gaps = 21/277 (7%)

Query: 31   GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
            GSP+ LTC +  + +    + +     ++ A+    S   +LQ++ +     G+Y C A+
Sbjct: 3139 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 3198

Query: 90   TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
               ++  +     + V  R+  + V+ E       V+EG  + L C        D+ +L 
Sbjct: 3199 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 3253

Query: 148  YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
                +G ++    +  L      +  +R SDA  Y CVA N  G   + L ++ V +P  
Sbjct: 3254 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 3310

Query: 207  RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
             P +   A  +   V    +++ + C  +RGSPPI   +  +   + L  R+   G G +
Sbjct: 3311 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 3368

Query: 262  FNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
              +S  +   +G ++C A +  G       TL   VP
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAGV-ADRNFTLQVQVP 3404



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 61/238 (25%), Positives = 85/238 (35%), Gaps = 34/238 (14%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            L +A++   D+G Y C+A         SRR+++ V+  P   +  + +      M G  L
Sbjct: 1263 LFLASVSPADSGDYECQATNEVGST--SRRAKLVVYVPP--SIREDGRKANVSGMAGQSL 1318

Query: 131  VLICSVAMGTGDITFLWYKGA--VGLNL------------QSKTQRSLTAEYEI--PSVR 174
             L C  A G      +W K A  VG+ L            Q    R L     +  P ++
Sbjct: 1319 TLECD-ANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQ 1377

Query: 175  ESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQ----AAVEDVLELHCE 230
            E D+  Y C AEN      +G       + V  P  +L A  AQ     A  DV EL C 
Sbjct: 1378 EGDSGLYSCRAEN-----QAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADV-ELQCW 1431

Query: 231  ALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH---SGNYSCEANNGLGAQ 285
                  P + W       L              L +T  H    G Y C A +  G Q
Sbjct: 1432 TSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 1489


>gi|13489095 sialoadhesin precursor [Homo sapiens]
          Length = 1709

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 83/318 (26%), Positives = 125/318 (39%), Gaps = 42/318 (13%)

Query: 16  PAELFLIASPS--HPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
           P  + ++ SPS  +   G  VTLTC++    S  A     + +D   L    + +  L +
Sbjct: 238 PKGVKILLSPSGRNILPGELVTLTCQVN--SSYPAVSSIKWLKDGVRLQ---TKTGVLHL 292

Query: 74  AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLI 133
                 D G Y C+A+     ++      I++H + +A+V +    P G ++E   + L+
Sbjct: 293 PQAAWSDAGVYTCQAENGVGSLVSP---PISLH-IFMAEVQVS---PAGPILENQTVTLV 345

Query: 134 CSVAM-GTGDITFLWYKGAVGL-NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGP 191
           C+       D+ + WYK  V L +  S T R   A         +D   Y+C  +N +G 
Sbjct: 346 CNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLAT-------RADTGFYFCEVQNVHGS 398

Query: 192 SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGS 251
             SG VS+ V  P   P+L       QA +  +  LHC  +   P       H    L S
Sbjct: 399 ERSGPVSVVVNHPPLTPVLTAFL-ETQAGLVGI--LHCSVV-SEPLATLVLSHGGHILAS 454

Query: 252 RSAPSGGGASFN------------LSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTG 299
            S  S     F+              L E  SG Y C A N LG   S   TL+F     
Sbjct: 455 TSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATS---TLDFHANAA 511

Query: 300 ARSNHLTSGVIEGLLSTL 317
                  + V+EG   TL
Sbjct: 512 RLLISPAAEVVEGQAVTL 529



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 71/291 (24%), Positives = 109/291 (37%), Gaps = 48/291 (16%)

Query: 22  IASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDT 81
           IASP    EG+ V   C  P++         C     R    G   +  +   +   E T
Sbjct: 144 IASPVELLEGTEVDFNCSTPYV---------CLQEQVRLQWQGQDPARSVTFNSQKFEPT 194

Query: 82  GSYWCEAQTMA------SKVLR------SRRSQINVH---RVPVADVSLETQPPGGQVME 126
           G    E   MA       ++LR      + R+Q  +H   +     V +   P G  ++ 
Sbjct: 195 GVGHLETLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILP 254

Query: 127 GDRLVLICSVAMGTGDITFL-WYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
           G+ + L C V      ++ + W K   G+ LQ+K     T    +P    SDA  Y C A
Sbjct: 255 GELVTLTCQVNSSYPAVSSIKWLKD--GVRLQTK-----TGVLHLPQAAWSDAGVYTCQA 307

Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLR---APRAQAAVEDVLELHCEALRGSPPILYWF 242
           ENG G          V  P+S  I M     +P         + L C     +P  L + 
Sbjct: 308 ENGVGS--------LVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYS 359

Query: 243 YHEDITLGSRSAPSGGGASFNLSL-TEEHSGNYSCEANNGLGAQRSEAVTL 292
           ++++  L           +  L L T   +G Y CE  N  G++RS  V++
Sbjct: 360 WYKNHVL----LEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSV 406



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 68/273 (24%), Positives = 105/273 (38%), Gaps = 48/273 (17%)

Query: 83   SYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGD 142
            +Y C AQ +   +    R Q+   RV VA+       PG  V EG  L L C +  G G 
Sbjct: 1422 TYVCTAQNLLGSISTIGRLQVEGARV-VAE-------PGLDVPEGAALNLSCRLLGGPGP 1473

Query: 143  I---TFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSI 199
            +   TF W+     L+ +     + T       V  + A  Y+C+AE   G + S  V +
Sbjct: 1474 VGNSTFAWFWNDRRLHAEPVPTLAFT------HVARAQAGMYHCLAELPTGAAASAPVML 1527

Query: 200  TVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGG 259
             V  P   P +M+     +  +  +L+   +    S P+     H    L + S P G  
Sbjct: 1528 RVLYPPKTPTMMVFV-EPEGGLRGILDCRVD----SEPLASLTLHLGSRLVASSQPQGAP 1582

Query: 260  ASFNL--------------SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHL 305
            A  ++              +L     G Y C A+N LG   S + +  F V    R +  
Sbjct: 1583 AEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLG---SASTSTYFGVRALHRLHQF 1639

Query: 306  TS-----GVIEGLLSTLGPATVALLFCYGLKRK 333
                   G++ GLL  L    + L  CY  +R+
Sbjct: 1640 QQLLWVLGLLVGLLLLL----LGLGACYTWRRR 1668



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 57/245 (23%), Positives = 91/245 (37%), Gaps = 41/245 (16%)

Query: 66   SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
            ++S KL++  +   D+GSY CEA  +      S   Q+    V V+        P  ++ 
Sbjct: 856  ANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVS--------PSPELQ 907

Query: 126  EGDRLVLICSVAMGTGDIT-FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
            EG  +VL C V  G  + T + WY+    L      Q S +A     ++  + A  Y+C 
Sbjct: 908  EGQAVVLSCQVHTGVPEGTSYRWYRDGQPL------QESTSATLRFAAITLTQAGAYHCQ 961

Query: 185  AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV----LELHCEALRGSPPILY 240
            A+        G  + ++  P+S  +           + D     L L    +   PP   
Sbjct: 962  AQ------APGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQL 1015

Query: 241  WFYHED----ITLGSRSAPSGGGASFNLSLTE------------EHSGNYSCEANNGLGA 284
               H D     TL     P G     ++++              E  G Y CEA+N LG 
Sbjct: 1016 RLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQ 1075

Query: 285  QRSEA 289
              + A
Sbjct: 1076 ASASA 1080



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 73/304 (24%), Positives = 121/304 (39%), Gaps = 62/304 (20%)

Query: 21   LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKED 80
            ++A  +   EG+P+T+TC  P   ++ A   + ++ + R L  G ++S    +A   +  
Sbjct: 1264 ILAPEAAVPEGAPITVTCADP---AAHAPTLYTWYHNGRWLQEGPAASLSFLVAT--RAH 1318

Query: 81   TGSYWCEAQTMASKVLRSRRSQINVHRVP-----------------VADVSLETQPPGGQ 123
             G+Y C+AQ  A     SR + + V   P                 V   +++++PP   
Sbjct: 1319 AGAYSCQAQD-AQGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAVIQCTVDSEPPAEL 1377

Query: 124  VMEGDRLVL-----ICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
             +  D  VL     + S+A GTG +     + A+ L +Q           ++P    +  
Sbjct: 1378 ALSHDGKVLATSSGVHSLASGTGHVQVA--RNALRLQVQ-----------DVP----AGD 1420

Query: 179  EQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
            + Y C A+N  G  S  G + +     V+ P   L  P   A     L L C  L G  P
Sbjct: 1421 DTYVCTAQNLLGSISTIGRLQVEGARVVAEP--GLDVPEGAA-----LNLSCRLLGGPGP 1473

Query: 238  I----LYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
            +      WF++ D  L +   P+    +F   +    +G Y C A    GA  S  V L 
Sbjct: 1474 VGNSTFAWFWN-DRRLHAEPVPT---LAFT-HVARAQAGMYHCLAELPTGAAASAPVMLR 1528

Query: 294  FTVP 297
               P
Sbjct: 1529 VLYP 1532



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 65/267 (24%), Positives = 104/267 (38%), Gaps = 29/267 (10%)

Query: 30   EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
            EG  V LTC +    +  AQ  + +++D    G     +  + +  +   D  SY C   
Sbjct: 1099 EGQLVNLTCLV--WTTHPAQLTYTWYQD----GQQRLDAHSIPLPNVTVRDATSYRCGVG 1152

Query: 90   TMASKVLRSRRSQINVHRVPV-ADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWY 148
                    SR   ++V   P    ++   +  GGQ+      +++C+V         L +
Sbjct: 1153 PPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLA-----LVLCTVDSRPPAQLALSH 1207

Query: 149  KGAVGLNLQSKTQRSL--TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
             G +   L S T  S+  T   E+   +  D   Y C A +  G + +   S+ +R+   
Sbjct: 1208 AGRL---LASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANT---SLELRLEGV 1261

Query: 207  RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFN-LS 265
            R IL   AP A       + + C       P LY +YH       R    G  AS + L 
Sbjct: 1262 RVIL---APEAAVPEGAPITVTCADPAAHAPTLYTWYHN-----GRWLQEGPAASLSFLV 1313

Query: 266  LTEEHSGNYSCEANNGLGAQRSEAVTL 292
             T  H+G YSC+A +  G + S    L
Sbjct: 1314 ATRAHAGAYSCQAQDAQGTRSSRPAAL 1340



 Score = 36.6 bits (83), Expect = 0.045
 Identities = 75/305 (24%), Positives = 101/305 (33%), Gaps = 43/305 (14%)

Query: 17  AELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAM 76
           A   LI+  +   EG  VTL+C+     + DA+F +         GPG S    L + A 
Sbjct: 510 AARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSS----LLLPAA 565

Query: 77  WKEDTGSYWCEAQTMASKVLRSRRSQINV---HRVPVADVSLETQPPGGQVMEGDRLVLI 133
              D GSY C A+   S    S  + + V    R P     L+    G     G R +L+
Sbjct: 566 SSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGA--GRRGLLL 623

Query: 134 CSVAMGTGDITFLWYKG-AVGLNLQS-----------------KTQRSLTAEYEIPSVRE 175
           C V         L +K   V  +L S                 K    L  E   P + E
Sbjct: 624 CRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEE 683

Query: 176 SDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR-- 233
                Y C A N  G   +   S T      +  ++  AP           L C   R  
Sbjct: 684 EGL--YLCEASNALG---NASTSATFN---GQATVLAIAPSHTLQEGTEANLTCNVSREA 735

Query: 234 -GSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
            GSP    WF +     G   A         L +    +  Y+C      GAQ S  V L
Sbjct: 736 AGSPANFSWFRN-----GVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLL 790

Query: 293 NFTVP 297
           +   P
Sbjct: 791 SVLYP 795


>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 71/323 (21%), Positives = 131/323 (40%), Gaps = 33/323 (10%)

Query: 30  EGSPVTLTCKMPFLQSSDAQF-----QFCFFRDTRALGPGW-------SSSPKLQIAAMW 77
           EG   T++C++     S  Q      Q  +FRD R L           SS  K+ +  + 
Sbjct: 56  EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115

Query: 78  KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
             D G Y+C+  T   +   +  + +   R  + D+  +T       +EG+ + + C+  
Sbjct: 116 ISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT------AVEGEEIEVNCTAM 169

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR-----SLTAEYEIPSVRESDAEQYYCVAENGYGPS 192
                 T  W+KG   L  +S+ +      ++T++  +   +E D     C  E+   P+
Sbjct: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH---PA 226

Query: 193 PSGLVS----ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
            +G +     + V+      I M    +      D LEL CEA+    P++  +   D  
Sbjct: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286

Query: 249 LGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSN--HLT 306
           +   +  SG     N +L +  +G Y CEA+N +G   S+ +   +    G   +   + 
Sbjct: 287 MPQHAVLSGPNLFIN-NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVD 345

Query: 307 SGVIEGLLSTLGPATVALLFCYG 329
             VI G+++ +  A + LL   G
Sbjct: 346 HAVIGGVVAVVVFAMLCLLIILG 368


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 64/227 (28%), Positives = 95/227 (41%), Gaps = 17/227 (7%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            L+I    K D G Y CE +  A + +    + ++    P     LE      +   GD +
Sbjct: 6043 LEILNSTKRDAGQYSCEIENEAGRDVCG--ALVSTLEPPYFVTELEPL----EAAVGDSV 6096

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYCVAEN 187
             L C VA GT +IT  WYKG   L    + +   T   A      V  +D+ +Y C AEN
Sbjct: 6097 SLQCQVA-GTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAEN 6155

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G + S  V   ++     P    +    +  V   + L C  L GS PI   +Y + +
Sbjct: 6156 SIGTASSKTV-FRIQERQLPPSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGV 6213

Query: 248  TLGS----RSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEA 289
             L      +++     A+  +  T+  HSG YSC A+N LG   S A
Sbjct: 6214 LLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA 6260



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 30/278 (10%)

Query: 32   SPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDTGSY 84
            S V  TC++    +     +  +F+D + +             +  L+I  +   D G++
Sbjct: 4124 SVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNF 4183

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C A        +     + V   P    S  T+P    V+ G   V + S   G+  +T
Sbjct: 4184 TCRATNSVGS--KDSSGALIVQEPP----SFVTKPGSKDVLPGSA-VCLKSTFQGSTPLT 4236

Query: 145  FLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITV 201
              W+KG   L        T+ +L +  E+  V+ SD+  Y C   N      +G V  + 
Sbjct: 4237 IRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSN-----VAGGVECSA 4291

Query: 202  RIPVSRPILMLR--APRAQAAVEDVLELHCEALRGSPPI-LYWFYHE-DITLGSRSAPSG 257
             + V  P   +    P       D  +L C+ + G+PPI + WF ++ +I   S+   S 
Sbjct: 4292 NLFVKEPATFVEKLEPSQLLKKGDATQLACK-VTGTPPIKITWFANDREIKESSKHRMSF 4350

Query: 258  GGASFNLSLTE---EHSGNYSCEANNGLGAQRSEAVTL 292
              ++  L LT+   E SG Y CEA N  G+    ++ +
Sbjct: 4351 VESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 4388



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 21/229 (9%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            L+I +   ED G Y C  +  + K   S  +QI +   P     LE      +V  GD  
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGK--DSCSAQILILEPPYFVKQLEPV----KVSVGDSA 7978

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCVAEN 187
             L C +A GT +I   WYKG   L   +  +   R+  A      V  +D+ +Y C AEN
Sbjct: 7979 SLQCQLA-GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 8037

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G   S    +TV+     P    +    Q  V   +   C A+ GS PI   +Y +  
Sbjct: 8038 SVG-EVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGK 8095

Query: 248  TLGSRSAPS------GGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEA 289
             L  + +P+         A+ N+  T+   +G YSC A N +G+  S A
Sbjct: 8096 PL--KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSA 8142



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 72/283 (25%), Positives = 108/283 (38%), Gaps = 34/283 (12%)

Query: 29   TEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-------LQIAAMWKEDT 81
            T G PVTLTC++    +  A  Q C++RD   L    +           L+I       +
Sbjct: 6187 TVGLPVTLTCRL----NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHS 6242

Query: 82   GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
            G Y C A         S R      R P      + +P    V+ G+     C V  G  
Sbjct: 6243 GQYSCSASNPLGTASSSARLTA---REPKKSPFFDIKPVSIDVIAGESADFECHVT-GAQ 6298

Query: 142  DITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
             +   W K    +        T    T    I  V + D+ QY C A N  G        
Sbjct: 6299 PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD-----M 6353

Query: 199  ITVRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPI-LYWF-----YHEDITLG 250
             + ++ V  P   ++   A    +  + ++L C+ + GSP I + WF      HE     
Sbjct: 6354 CSAQLSVKEPPKFVKKLEASKVAKQGESIQLECK-ISGSPEIKVSWFRNDSELHESWKYN 6412

Query: 251  SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
                 S    + N +  E+ SG+Y CEA+NG+G A  S A+T+
Sbjct: 6413 MSFINSVALLTINEASAED-SGDYICEAHNGVGDASCSTALTV 6454



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 64/292 (21%), Positives = 113/292 (38%), Gaps = 44/292 (15%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
            EPA +   A P   T G   TL CK+    +   +    +++D + L          ++ 
Sbjct: 5702 EPAVIVEKAGPMTVTVGETCTLECKV----AGTPELSVEWYKDGKLLTSSQKHKFSFYNK 5757

Query: 68   SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
               L+I ++ ++D G+Y  + Q    K   +    ++   VP    +   +  GG +  G
Sbjct: 5758 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP-PSFTRRLKNTGGVL--G 5814

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYCV 184
               +L C VA G+  I+  W+     +   +K Q + +      ++ S+  SD   Y CV
Sbjct: 5815 ASCILECKVA-GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 5873

Query: 185  AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWFY 243
            A N  G      V     + V  P   ++ P     +          +RG+PP  + WF 
Sbjct: 5874 AANVAGSDECRAV-----LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWF- 5927

Query: 244  HEDITLGSRSAPSGGGAS------------FNLSLTEEHSGNYSCEANNGLG 283
                  G+R    G   +            FN+ +++  SG Y+C  +N  G
Sbjct: 5928 -----RGARELVKGDRCNIYFEDTVAELELFNIDISQ--SGEYTCVVSNNAG 5972



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 67/264 (25%), Positives = 111/264 (42%), Gaps = 43/264 (16%)

Query: 50   FQFCFFRDTRALGPGWSSS-------PKLQIAAMWKEDTGSYWCEAQTMASKV-----LR 97
            F+  +F+ +R L PG S +        +L++  +   ++G Y C     A        L 
Sbjct: 6863 FKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 6922

Query: 98   SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ 157
             +     V R+  AD S+ET  P          +++ +   GT  I+  W K    ++  
Sbjct: 6923 VKEPATFVKRL--ADFSVETGSP----------IVLEATYTGTPPISVSWIKDEYLISQS 6970

Query: 158  SKTQRSLTAEYEIPSVRESDAE---QYYCVAENGYGPSP-SGLVSITVRIPVSRPILMLR 213
             +   ++T +  I  + ES  E   QY C+ EN  G      LVS+     +  P  +  
Sbjct: 6971 ERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV-----LEPPYFIEP 7025

Query: 214  APRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPS------GGGASFNLSLT 267
                +A + +   L C+ + G+P I   +Y E   L  RSAP+         AS  ++  
Sbjct: 7026 LEHVEAVIGEPATLQCK-VDGTPEIRISWYKEHTKL--RSAPAYKMQFKNNVASLVINKV 7082

Query: 268  EEHS-GNYSCEANNGLGAQRSEAV 290
            +    G YSC+A+N +GA  S AV
Sbjct: 7083 DHSDVGEYSCKADNSVGAVASSAV 7106



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 62/276 (22%), Positives = 102/276 (36%), Gaps = 30/276 (10%)

Query: 30   EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW-------SSSPKLQIAAMWKEDTG 82
            +G  + L CK+    S   + +  +FR+   L   W       +S   L I     ED+G
Sbjct: 6378 QGESIQLECKI----SGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 6433

Query: 83   SYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGD 142
             Y CEA         S  + + V   PV       +P     ++G  ++L C ++ GT  
Sbjct: 6434 DYICEAHNGVGDA--SCSTALTVKAPPV----FTQKPSPVGALKGSDVILQCEIS-GTPP 6486

Query: 143  ITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSI 199
               +W K    +    K   T +       I ++  SD  +Y+C A N  G S +   S+
Sbjct: 6487 FEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG-SDTCSCSV 6545

Query: 200  TVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITL----GSRSAP 255
              + P   P  + +       + D +EL        P  + W       +     +R + 
Sbjct: 6546 KFKEP---PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF 6602

Query: 256  SGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAV 290
                A+  L   E  +SG Y C+  N  G +   AV
Sbjct: 6603 IDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAV 6638



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 61/294 (20%), Positives = 120/294 (40%), Gaps = 30/294 (10%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQ-- 72
            EPA++   A     TE  P+TL C +    +   + +  + +D + + P    S   +  
Sbjct: 5139 EPAQIVEKAKSVDVTEKDPMTLECVV----AGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194

Query: 73   -----IAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
                 I ++ K+D+G Y  + +            ++    +P +     T+      + G
Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKM---DKVLG 5251

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCV 184
              + + C V+ G+  I+  W+K    ++  +K +      +   E+ ++   D   Y C 
Sbjct: 5252 SSIHMECKVS-GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCK 5310

Query: 185  AENGYGPSP-SGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
              N  G    SG+  +TV+ P   P  +++  R QA  +  +E     L+G+PP    ++
Sbjct: 5311 VSNVAGDDACSGI--LTVKEP---PSFLVKPGRQQAIPDSTVEFKA-ILKGTPPFKIKWF 5364

Query: 244  HEDITLGSRS----APSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTL 292
             +D+ L S         G  +  NL S+    +G Y+C   N +G+     + L
Sbjct: 5365 KDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 5418



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 67/291 (23%), Positives = 102/291 (35%), Gaps = 57/291 (19%)

Query: 27   HPTEGSPVTLTCKMP-------------FLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
            H T G PV   C++               L   DA  Q  F  +   L          QI
Sbjct: 7126 HETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL----------QI 7175

Query: 74   AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLI 133
                +   G Y C A         S +  ++ H VP      + +P    +  G+     
Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPF---FDLKPVSVDLALGESGTFK 7232

Query: 134  CSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAENGYG 190
            C V  GT  I   W K    +      + +L   TA   +  V + DA QY C A N  G
Sbjct: 7233 CHVT-GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAG 7291

Query: 191  PSPSGLVSITVRIPVSRPILMLRA--PRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
                   S + ++ V  P   ++   P      ++     C+ + GSP I   +Y ++  
Sbjct: 7292 KD-----SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECK-IGGSPEIKVLWYKDETE 7345

Query: 249  LGSRSAPSGGGASFNLS------------LTEEHSGNYSCEANNGLGAQRS 287
            +   S        F +S            L+ E SG+Y+CEA+N  G+  S
Sbjct: 7346 IQESS-------KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASS 7389



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 33/292 (11%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
            EP        P     G  VT T  +         F+  +FR  R L  G         +
Sbjct: 5891 EPPSFVKEPEPLEVLPGKNVTFTSVI----RGTPPFKVNWFRGARELVKGDRCNIYFEDT 5946

Query: 68   SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
              +L++  +    +G Y C     A +   + R  +      +  +S  +  PG      
Sbjct: 5947 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPG------ 6000

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCV 184
             + +++ S   GT  I+  W K    +    K     T +    EI +  + DA QY C 
Sbjct: 6001 -KSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCE 6059

Query: 185  AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
             EN  G    G +  T+      P  +      +AAV D + L C+ + G+P I   +Y 
Sbjct: 6060 IENEAGRDVCGALVSTLE----PPYFVTELEPLEAAVGDSVSLQCQ-VAGTPEITVSWYK 6114

Query: 245  EDITLGS----RSAPSGGGAS--FNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
             D  L      R+  +   A+  FN  +    SG Y+C+A N +G   S+ V
Sbjct: 6115 GDTKLRPTPEYRTYFTNNVATLVFN-KVNINDSGEYTCKAENSIGTASSKTV 6165



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/296 (23%), Positives = 109/296 (36%), Gaps = 46/296 (15%)

Query: 15   EPAELFLIASPSH-PTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WS 66
            EP        PS+    G    L CK+          Q  +F++ + L           +
Sbjct: 3735 EPPSFVKKVDPSYLMLPGESARLHCKL----KGSPVIQVTWFKNNKELSESNTVRMYFVN 3790

Query: 67   SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
            S   L I  +  ED+GSY CEA         S  ++I +   P    +LE       ++ 
Sbjct: 3791 SEAILDITDVKVEDSGSYSCEAVNDVGS--DSCSTEIVIKEPPSFIKTLEP----ADIVR 3844

Query: 127  GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK----TQRSLTAEYEIPSVRESDAEQYY 182
            G   +L C V+ GTG     W+K    +    K    +Q+SL    EI S   +D  +Y 
Sbjct: 3845 GTNALLQCEVS-GTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYE 3902

Query: 183  CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCE------ALRGSP 236
            CV  N  G           +       L+   P     V+D++ L  +      A+RGS 
Sbjct: 3903 CVVANEVG-----------KCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSE 3951

Query: 237  PI-LYWFYHEDITLG----SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
            PI + W   +++         S  +G        +     G Y+C A N  G+Q S
Sbjct: 3952 PISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTS 4007



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 70/268 (26%), Positives = 110/268 (41%), Gaps = 26/268 (9%)

Query: 67   SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
            S+  L++  +  ED+G Y CEAQ  A     S  S + V   P    + E +P   +V++
Sbjct: 4353 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS--SIVIVKESPY--FTKEFKPI--EVLK 4406

Query: 127  GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYC 183
               ++L+  VA GT      W+K    L    K +  +       +I     +DA +Y C
Sbjct: 4407 EYDVMLLAEVA-GTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQC 4465

Query: 184  VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWF 242
               N  G S       + R+ +  P   ++   + +++          L+GS PI + W 
Sbjct: 4466 RVTNEVGSS-----ICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWL 4520

Query: 243  YHED-ITLGS--RSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPT 298
               D IT     R       AS  LS  E +H G Y C+A N  G QR  A+ L+   P 
Sbjct: 4521 KDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSAL-LSVKEPA 4579

Query: 299  GARSNHLTSGVIEGLLSTLGPATVALLF 326
                  ++  V +G      PAT+ + F
Sbjct: 4580 TITEEAVSIDVTQG-----DPATLQVKF 4602



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 52/227 (22%), Positives = 97/227 (42%), Gaps = 17/227 (7%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQ + +   + G Y C+ +  A   ++   + ++V    +   ++  +P   +V  GD  
Sbjct: 7550 LQFSRVEPANAGKYTCQIKNDAG--MQECFATLSV----LEPATIVEKPESIKVTTGDTC 7603

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAEN 187
             L C+VA GT +++  W+K    L   +K + S     +  +I +V  SD+  Y    +N
Sbjct: 7604 TLECTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQN 7662

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G   S   S+ V      P    +           + + C+   GSPPI   ++HE  
Sbjct: 7663 PVGKD-SCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFHEGN 7720

Query: 248  TLGS----RSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEA 289
             + S    ++  +    +  +++ EE  SG+Y+C A N  G+    A
Sbjct: 7721 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA 7767



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 20/196 (10%)

Query: 112  DVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYE-- 169
            DV + +     QV+E  R V+   V     D+   WYK  + +N Q + +     E    
Sbjct: 3146 DVRIRSIKKEVQVIEKQRAVVEFEV--NEDDVDAHWYKDGIEINFQVQERHKYVVERRIH 3203

Query: 170  ---IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE 226
               I   R+SDA +Y  VA            S+T+ +    P  +L+  +          
Sbjct: 3204 RMFISETRQSDAGEYTFVAGRNRS-------SVTLYVNAPEPPQVLQELQPVTVQSGKPA 3256

Query: 227  LHCEALRGSP-PILYWFYHED-ITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNG 281
              C  + G P P + W+  E  ++ G +      G  + L L E   E +  Y+CEA N 
Sbjct: 3257 RFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKND 3316

Query: 282  LGAQRSEAVTLNFTVP 297
             G   + A +L+  VP
Sbjct: 3317 YGVATTSA-SLSVEVP 3331



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 56/231 (24%), Positives = 96/231 (41%), Gaps = 13/231 (5%)

Query: 67   SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
            +S  L +  + K D+G Y C A     K   S  +Q+N+    +     +      +  E
Sbjct: 8206 NSAHLTVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVEETE 8263

Query: 127  GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYC 183
            G+   L   VA G+  IT  WYK  + +   S    T ++ T   ++     +DA  Y C
Sbjct: 8264 GNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 8322

Query: 184  VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWF 242
               N  G S     SI ++ P   P+          +  + ++L C  ++GS PI + W 
Sbjct: 8323 KVSNDAG-SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCH-VQGSEPIRIQWL 8380

Query: 243  YH-EDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLGAQRSEA 289
                +I    R + S    +  L L +     SG+Y C+A+N  G+  +++
Sbjct: 8381 KAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKS 8431



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 73/295 (24%), Positives = 107/295 (36%), Gaps = 43/295 (14%)

Query: 11   APLC--EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG---- 64
            APL   EP        P     G+ VT T     +      F   +F+ +  L PG    
Sbjct: 7767 APLTVREPPSFVQKPDPMDVLTGTNVTFTS----IVKGTPPFSVSWFKGSSELVPGDRCN 7822

Query: 65   ---WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVA---DVSLETQ 118
                 S  +L++  +    +G Y C     A K   +    I      V    D S+E  
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKG 7882

Query: 119  PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRE 175
             P   ++EG           GT  I+  W K  + +    +   T    +A  EIPS   
Sbjct: 7883 KP--LILEG--------TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTV 7932

Query: 176  SDAEQYYCVAENGYGPSPSGLVSITVRIPV-SRPILMLRAPRAQAAVEDVLELHCEALRG 234
             DA QY C  EN      SG  S + +I +   P  + +    + +V D   L C+ L G
Sbjct: 7933 EDAGQYNCYIENA-----SGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQ-LAG 7986

Query: 235  SPPILYWFYHEDITLGSRSA------PSGGGASFNLSLTEEHSGNYSCEANNGLG 283
            +P I   +Y  D  L   +        +     FN  +    SG Y C+A N +G
Sbjct: 7987 TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFN-QVDINDSGEYICKAENSVG 8040



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 55/229 (24%), Positives = 85/229 (37%), Gaps = 20/229 (8%)

Query: 72   QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
            QI+    E++G+Y CEA+  A     S   ++ V   P     L+      +V++   + 
Sbjct: 4920 QISGARVENSGTYVCEARNDAGTA--SCSIELKVKEPPTFIRELKPV----EVVKYSDVE 4973

Query: 132  LICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENG 188
            L C V  GT      W K    +    K   T R       I     SD  +Y C+  N 
Sbjct: 4974 LECEVT-GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN- 5031

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
                  G  S + R+ +  P   ++       V          + GSPPI   +  +D  
Sbjct: 5032 ----EGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 5087

Query: 249  LGSRS----APSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTL 292
            L        +     A+  + S+   HSG Y+C+A N  G +R  A  L
Sbjct: 5088 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 5136



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 70/271 (25%), Positives = 104/271 (38%), Gaps = 34/271 (12%)

Query: 31   GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDTGS 83
            GS + + CK+       AQ+    F+D + +             S  L++  +  EDT +
Sbjct: 5251 GSSIHMECKVSGSLPISAQW----FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 5306

Query: 84   YWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDI 143
            Y C+   +A     S    + V   P   V      PG Q    D  V   ++  GT   
Sbjct: 5307 YTCKVSNVAGDDACS--GILTVKEPPSFLVK-----PGRQQAIPDSTVEFKAILKGTPPF 5359

Query: 144  TFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
               W+K  V L    K    L   T+   + SV  S   QY C   N  G       S T
Sbjct: 5360 KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSD-----SCT 5414

Query: 201  VRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPI-LYWFYHEDITLGS---RSA 254
              + V+ P   ++   A   V+  D   L C+ + GSP I + WF +E     S   R  
Sbjct: 5415 TMLLVTEPPKFVKKLEASKIVKAGDSSRLECK-IAGSPEIRVVWFRNEHELPASDKYRMT 5473

Query: 255  PSGGGASFNLS-LTEEHSGNYSCEANNGLGA 284
                 A   ++ L+ E SG++ CEA N  G+
Sbjct: 5474 FIDSVAVIQMNNLSTEDSGDFICEAQNPAGS 5504



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 52/235 (22%), Positives = 92/235 (39%), Gaps = 20/235 (8%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            +Q+  +  ED+G + CEAQ  A     S  +++ V   PV      + PP  + ++   +
Sbjct: 5481 IQMNNLSTEDSGDFICEAQNPAGST--SCSTKVIVKEPPV----FSSFPPIVETLKNAEV 5534

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAEN 187
             L C ++ GT     +WYK    L    K     ++      I +V  SD  +Y+C A+N
Sbjct: 5535 SLECELS-GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G S + + ++ ++ P   P  + +         +  EL        P  + W   ++ 
Sbjct: 5594 EVG-SDTCVCTVKLKEP---PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649

Query: 248  TL----GSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
             +      R       A+   +  E  ++G Y C+  N  G  R    TL    P
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND-GGMRENMATLMVLEP 5703



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 56/228 (24%), Positives = 84/228 (36%), Gaps = 17/228 (7%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ-VMEGDR 129
            LQ A     + G Y C+ +            + N+  + V + ++  +  G   V  G+ 
Sbjct: 5668 LQFAKAEPANAGKYICQIKNDGGM-------RENMATLMVLEPAVIVEKAGPMTVTVGET 5720

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAE 186
              L C VA GT +++  WYK    L    K + S     +   I SV   DA  Y    +
Sbjct: 5721 CTLECKVA-GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQ 5779

Query: 187  NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
            N  G S    V + V      P    R       +     L C+    SP  + WF+ + 
Sbjct: 5780 NNVGKSSCTAV-VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKT 5838

Query: 247  -ITLGSRSAPSGGGASFNL---SLTEEHSGNYSCEANNGLGAQRSEAV 290
             I  G++   +       L   SL     GNY+C A N  G+    AV
Sbjct: 5839 KIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 66/289 (22%), Positives = 107/289 (37%), Gaps = 26/289 (8%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKM---PFLQSSDAQFQFCFFRDTRALGPGWSSSPKL 71
            EPA      +      GSP+ L       P +  S  + ++   +  R        S  L
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 6984

Query: 72   QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
            +I     ED   Y C  +  A + +    + ++V   P     LE      + + G+   
Sbjct: 6985 EILESTIEDYAQYSCLIENEAGQDICE--ALVSVLEPPYFIEPLEHV----EAVIGEPAT 7038

Query: 132  LICSVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
            L C V  GT +I   WYK       A    +Q K      A   I  V  SD  +Y C A
Sbjct: 7039 LQCKVD-GTPEIRISWYKEHTKLRSAPAYKMQFKNN---VASLVINKVDHSDVGEYSCKA 7094

Query: 186  ENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHE 245
            +N  G   S  V + ++     P    +       +   +   C  + GS P+   +Y +
Sbjct: 7095 DNSVGAVASSAV-LVIKARKLPPFFARKLKDVHETLGFPVAFECR-INGSEPLQVSWYKD 7152

Query: 246  DITLGS----RSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEA 289
             + L      +++     A+  +  T++ H G Y+C A+N LG   S A
Sbjct: 7153 GVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 7201



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 21/130 (16%)

Query: 166  AEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP------VSRPILMLRAPRAQA 219
            A  EIP  +  D+  Y C A N  G S S   ++TVR P      V    LML    A+ 
Sbjct: 3699 ATLEIPLAKLKDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESAR- 3756

Query: 220  AVEDVLELHCEALRGSPPI-LYWFYH-EDITLGSRSAPSGGGASFNLSLTE---EHSGNY 274
                   LHC+ L+GSP I + WF + ++++  +        +   L +T+   E SG+Y
Sbjct: 3757 -------LHCK-LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSY 3808

Query: 275  SCEANNGLGA 284
            SCEA N +G+
Sbjct: 3809 SCEAVNDVGS 3818



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 20/227 (8%)

Query: 79   EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
            ED+G Y CEA   A     S  + + V   P+       +P   + ++G  + L C +  
Sbjct: 7371 EDSGDYTCEAHNAAGSA--SSSTSLKVKEPPI----FRKKPHPIETLKGADVHLECEL-Q 7423

Query: 139  GTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
            GT      WYK    L    K      +      I +V  +D  +Y C A N  G S + 
Sbjct: 7424 GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG-SDTC 7482

Query: 196  LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHE-DITLGSRS- 253
            + SI ++ P   P  + +       V   ++L        P  + WF  + +I   S + 
Sbjct: 7483 VGSIALKAP---PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNI 7539

Query: 254  --APSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
              + S   A+   S  E  ++G Y+C+  N  G Q   A TL+   P
Sbjct: 7540 WISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA-TLSVLEP 7585



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 70/298 (23%), Positives = 105/298 (35%), Gaps = 54/298 (18%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
            EPA +     P   T G+P  L C +       A+    +F+D R L           + 
Sbjct: 6643 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAK----WFKDGRELSADSKHHITFINK 6698

Query: 68   SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG------ 121
               L+I      D G Y  E +    K        ++VH      VS    PP       
Sbjct: 6699 VASLKIPCAEMSDKGLYSFEVKNSVGK----SNCTVSVH------VSDRIVPPSFIRKLK 6748

Query: 122  -GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESD 177
                + G  +VL C V+ G+  I+  W++    +    K Q S +       +  +  SD
Sbjct: 6749 DVNAILGASVVLECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSD 6807

Query: 178  AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
               Y CVA N  G      V     + V  P    + P +   +  +       +RG+PP
Sbjct: 6808 TGIYTCVAANVAGSDECSAV-----LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPP 6862

Query: 238  I-LYWFYHEDITLGSRSAPSGGGASFNLS--LTE--------EHSGNYSCEANNGLGA 284
              + WF       GSR    G   + +L   +TE          SG+YSC   N  G+
Sbjct: 6863 FKVKWF------KGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGS 6914



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 9/167 (5%)

Query: 124  VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQ 180
            V +GD   L    + GT +IT  W+K    L L SK + S+T   +  +I S  + D+ +
Sbjct: 4590 VTQGDPATLQVKFS-GTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGE 4648

Query: 181  YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
            Y    +N  G S S    I V   +  P    +  +  +     ++L C      P  + 
Sbjct: 4649 YTFEVQNDVGRS-SCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707

Query: 241  WFY-HEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG 283
            WF   ++I+   +   S    +  L +++     SG Y+C A N  G
Sbjct: 4708 WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 4754



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 46/177 (25%), Positives = 67/177 (37%), Gaps = 9/177 (5%)

Query: 123  QVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAE 179
            QV  GD   L  +VA GT ++   WYK    L    K + S     A+ +  S    D+ 
Sbjct: 4027 QVTAGDPATLEYTVA-GTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 4085

Query: 180  QYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPIL 239
            QY     N  G S S   + TV      P          + V     L C+     P  +
Sbjct: 4086 QYTFEISNEVGSS-SCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRV 4144

Query: 240  YWFYHEDITLGS---RSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVTL 292
             WF        S   R A   G AS  +   + + +GN++C A N +G++ S    +
Sbjct: 4145 SWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 4201



 Score = 36.2 bits (82), Expect = 0.059
 Identities = 57/294 (19%), Positives = 107/294 (36%), Gaps = 47/294 (15%)

Query: 29   TEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDT 81
            +EG P    C++     S    +  ++   + + P        +  + +L+IA  + ED 
Sbjct: 3357 SEGQPARFQCRV-----SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3411

Query: 82   GSYWCEAQTMASKV-------LRSRRSQINVHRVPVADVSLETQPPGGQVME------GD 128
            G+Y   A     +V       L +  S ++       ++ ++  P   + +E      G 
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGH 3471

Query: 129  RLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCVA 185
                 C +     ++ F W+K    +    K         +  EI   +  D  +Y C A
Sbjct: 3472 LAKFTCEI-QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 3530

Query: 186  ENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
             N YG  S +  +++T   P   P  + R       V    +  C       P++   + 
Sbjct: 3531 SNEYGSVSCTATLTVTEAYP---PTFLSRPKSLTTFVGKAAKFICTVT--GTPVIETIWQ 3585

Query: 245  EDITLGSRSAPSGGGASFNL---------SLTEEHSGNYSCEANNGLGAQRSEA 289
            +D   G+  +PS      +          +LT +  G YSC+A+N  GA   +A
Sbjct: 3586 KD---GAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQA 3636



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 11/125 (8%)

Query: 78    KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM-----EGDRLVL 132
             K+D       A+      +RS++  ++V +V VA  S+E  P  GQ+M     EG  +  
Sbjct: 31531 KKDLNMVVSAARISCGGAIRSQKG-VSVAKVKVA--SIEIGPVSGQIMHAVGEEGGHVKY 31587

Query: 133   ICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGY 189
             +C +          WY G   L    K   T     A   +  + + D   Y C   N Y
Sbjct: 31588 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 31647

Query: 190   GPSPS 194
             G   S
Sbjct: 31648 GEDSS 31652



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 66/317 (20%), Positives = 107/317 (33%), Gaps = 50/317 (15%)

Query: 7    LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
            L + AP  EP ++     P     G P      +    S   Q +  ++++ + L  G+ 
Sbjct: 3231 LYVNAP--EPPQVLQELQPVTVQSGKPARFCAVI----SGRPQPKISWYKEEQLLSTGFK 3284

Query: 67   -------SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
                       L +   + ED   Y CEA+        S    + V  V   D  +   P
Sbjct: 3285 CKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3344

Query: 120  PG-------GQVMEGDRLVLICSVAMGTGDITFLWY---KGAVGLNLQSKTQRSLTAEYE 169
            P            EG      C V+ GT D+   WY   K          TQ   T + E
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVS-GT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLE 3402

Query: 170  IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS----------------RPILMLR 213
            I      D   Y  VA N  G   S   ++++  P S                 P++  +
Sbjct: 3403 IAEAYPEDEGTYTFVASNAVG-QVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRK 3461

Query: 214  APRAQAAVEDVLELHCEALRGSPPILY-WF-----YHEDITLGSRSAPSGGGASFNLSLT 267
                + A+  + +  CE ++ +P + + WF      +E      RS+         L   
Sbjct: 3462 IEPLEVALGHLAKFTCE-IQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI-LRTQ 3519

Query: 268  EEHSGNYSCEANNGLGA 284
                G Y+C+A+N  G+
Sbjct: 3520 VVDCGEYTCKASNEYGS 3536



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%)

Query: 166 AEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVL 225
           A+  IP+V ++++ +Y   A NG G + S    + V+   + P  + R           +
Sbjct: 63  AKLTIPAVTKANSGRYSLKATNGSGQATS-TAELLVKAETAPPNFVQRLQSMTVRQGSQV 121

Query: 226 ELHCEALRGSPPILYWFYHEDITLGSR--SAPSGGGASFNLSLTE---EHSGNYSCEANN 280
            L    + G P  +  FY +   + S      S  G  ++L + E   E SG YS  A N
Sbjct: 122 RLQVR-VTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180

Query: 281 GLGAQRSEAVTL 292
            +G   S A  L
Sbjct: 181 SVGRATSTAELL 192



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 41/163 (25%), Positives = 61/163 (37%), Gaps = 24/163 (14%)

Query: 8    LICAPLCEPAELFLIASPSHPTEGSPVTL----TCKMPFLQSSDAQFQFCFFRDTRALGP 63
            L+C P    A+L +I  P+       VTL    TC M   Q S    +  +FR+ R L P
Sbjct: 8729 LVCGPHIASAKLTVI-EPAWERHLQDVTLKEGQTCTMT-CQFSVPNVKSEWFRNGRILKP 8786

Query: 64   GWSSSP-------KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLE 116
                         KL IA +  ED G Y C+ + + +       +++ +   P   +   
Sbjct: 8787 QGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETS------AELRIEAEP---IQFT 8837

Query: 117  TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK 159
             +     V E       C V+     +T  WYKG   L    K
Sbjct: 8838 KRIQNIVVSEHQSATFECEVSFDDAIVT--WYKGPTELTESQK 8878



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 18/146 (12%)

Query: 66   SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLE--------- 116
            S +  L++  + K D+G Y C+A  +A     + +S++ +   P    + +         
Sbjct: 8398 SGTAVLELRDVAKADSGDYVCKASNVAGS--DTTKSKVTIKDKPAVAPATKKAAVDGRLF 8455

Query: 117  --TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGA-VGLNLQSKT---QRSLTAEYEI 170
              ++P   +V+E      I  V  G       W KG    LN   +    Q+   A+ EI
Sbjct: 8456 FVSEPQSIRVVEKTTATFIAKVG-GDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 8514

Query: 171  PSVRESDAEQYYCVAENGYGPSPSGL 196
                ++D+  Y CVA N +G   S +
Sbjct: 8515 RDTTKTDSGLYRCVAFNEHGEIESNV 8540



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 117   TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSV 173
             T+P    V EG+     C    G    T  W +    L+  ++ Q + T   + +EI SV
Sbjct: 32565 TKPRSMTVYEGESARFSCDTD-GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSV 32623

Query: 174   RESDAEQYYCVAENGYG 190
             + SD   Y  V EN  G
Sbjct: 32624 QASDEGNYSVVVENSEG 32640


>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 65/290 (22%), Positives = 118/290 (40%), Gaps = 31/290 (10%)

Query: 30  EGSPVTLTCKMPFLQSSDAQF-----QFCFFRDTRALGPGW-------SSSPKLQIAAMW 77
           EG   T++C++     S  Q      Q  +FRD R L           SS  K+ +  + 
Sbjct: 56  EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115

Query: 78  KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
             D G Y+C+  T   +   +  + +   R  + D+  +T       +EG+ + + C+  
Sbjct: 116 ISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT------AVEGEEIEVNCTAM 169

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR-----SLTAEYEIPSVRESDAEQYYCVAENGYGPS 192
                 T  W+KG   L  +S+ +      ++T++  +   +E D     C  E+   P+
Sbjct: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH---PA 226

Query: 193 PSGLVS----ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
            +G +     + V+      I M    +      D LEL CEA+    P++  +   D  
Sbjct: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286

Query: 249 LGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPT 298
           +   +  SG     N +L +  +G Y CEA+N +G   S+ +   +  PT
Sbjct: 287 MPQHAVLSGPNLFIN-NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335


>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
           [Homo sapiens]
          Length = 1070

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 15/237 (6%)

Query: 62  GPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
           G  +    +L +A + + D G Y C A  +A +    RR  +N+    V   S   +P  
Sbjct: 367 GRVYQKGHELVLANIAESDAGVYTCHAANLAGQ----RRQDVNITVATVP--SWLKKPQD 420

Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
            Q+ EG    L C +   T   T +WY+  + ++  S+ +        I SV   D   Y
Sbjct: 421 SQLEEGKPGYLDC-LTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWY 479

Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPIL 239
            C++      +P+G +    R+ V   +     P+ Q  +E   E  + C A     P +
Sbjct: 480 RCMSS-----TPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTI 534

Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
            W   +  +L      + G   F   +T + +GNY+C A+NG   Q    V L   V
Sbjct: 535 KWERADGSSLPEWVTDNAGTLHF-ARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAV 590



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/183 (20%), Positives = 83/183 (45%), Gaps = 10/183 (5%)

Query: 79  EDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           +D+G++ C A+  +  +  RS  +  N+  +    V L+      ++    ++ L C + 
Sbjct: 94  QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ---YYCVAENGYGPSPS 194
            G    T+ W++    L+   ++  +++++    ++R +  E    Y C A + +G + S
Sbjct: 154 -GHPRPTYQWFRDGTPLS-DGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211

Query: 195 GLVSITVRIPVSRPILMLRAPR--AQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
              + T+ I       ++ AP+    A  E+ +  HC+     PP L W + ++  + +R
Sbjct: 212 SQ-NFTLSIADESFARVVLAPQDVVVARYEEAM-FHCQFSAQPPPSLQWLFEDETPITNR 269

Query: 253 SAP 255
           S P
Sbjct: 270 SRP 272



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 12/193 (6%)

Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWY-KGAVGLNLQSKTQRSLTAEYEIPSVRES 176
           QP     ++G R +L C V    G +   W   GA   + + +  +  +  +     R  
Sbjct: 37  QPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD-RLQ 94

Query: 177 DAEQYYCVAENGYG--PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEAL 232
           D+  + CVA +      + S   S  ++   + P++ L+ P ++A ++   +  L C   
Sbjct: 95  DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV-LKHPASEAEIQPQTQVTLRCHID 153

Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG-AQRSE 288
               P   WF         +S  +      NL+L     EHSG YSC A++  G A  S+
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213

Query: 289 AVTLNFTVPTGAR 301
             TL+    + AR
Sbjct: 214 NFTLSIADESFAR 226



 Score = 32.7 bits (73), Expect = 0.65
 Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 5/130 (3%)

Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
           +  VR  +A  Y C+ +   GP    ++  T+ +     + +       A  E+   + C
Sbjct: 288 LTQVRPRNAGIYRCIGQGQRGPPI--ILEATLHLAEIEDMPLFEPRVFTAGSEE--RVTC 343

Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS-LTEEHSGNYSCEANNGLGAQRSE 288
              +G P    W+ H  + L +       G    L+ + E  +G Y+C A N  G +R +
Sbjct: 344 LPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQD 403

Query: 289 AVTLNFTVPT 298
                 TVP+
Sbjct: 404 VNITVATVPS 413


>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor
           [Homo sapiens]
          Length = 1014

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 15/237 (6%)

Query: 62  GPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
           G  +    +L +A + + D G Y C A  +A +    RR  +N+    V   S   +P  
Sbjct: 367 GRVYQKGHELVLANIAESDAGVYTCHAANLAGQ----RRQDVNITVATVP--SWLKKPQD 420

Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
            Q+ EG    L C +   T   T +WY+  + ++  S+ +        I SV   D   Y
Sbjct: 421 SQLEEGKPGYLDC-LTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWY 479

Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPIL 239
            C++      +P+G +    R+ V   +     P+ Q  +E   E  + C A     P +
Sbjct: 480 RCMSS-----TPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTI 534

Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
            W   +  +L      + G   F   +T + +GNY+C A+NG   Q    V L   V
Sbjct: 535 KWERADGSSLPEWVTDNAGTLHF-ARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAV 590



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/183 (20%), Positives = 83/183 (45%), Gaps = 10/183 (5%)

Query: 79  EDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           +D+G++ C A+  +  +  RS  +  N+  +    V L+      ++    ++ L C + 
Sbjct: 94  QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ---YYCVAENGYGPSPS 194
            G    T+ W++    L+   ++  +++++    ++R +  E    Y C A + +G + S
Sbjct: 154 -GHPRPTYQWFRDGTPLS-DGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211

Query: 195 GLVSITVRIPVSRPILMLRAPR--AQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
              + T+ I       ++ AP+    A  E+ +  HC+     PP L W + ++  + +R
Sbjct: 212 SQ-NFTLSIADESFARVVLAPQDVVVARYEEAM-FHCQFSAQPPPSLQWLFEDETPITNR 269

Query: 253 SAP 255
           S P
Sbjct: 270 SRP 272



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 12/193 (6%)

Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWY-KGAVGLNLQSKTQRSLTAEYEIPSVRES 176
           QP     ++G R +L C V    G +   W   GA   + + +  +  +  +     R  
Sbjct: 37  QPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD-RLQ 94

Query: 177 DAEQYYCVAENGYG--PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEAL 232
           D+  + CVA +      + S   S  ++   + P++ L+ P ++A ++   +  L C   
Sbjct: 95  DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV-LKHPASEAEIQPQTQVTLRCHID 153

Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG-AQRSE 288
               P   WF         +S  +      NL+L     EHSG YSC A++  G A  S+
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213

Query: 289 AVTLNFTVPTGAR 301
             TL+    + AR
Sbjct: 214 NFTLSIADESFAR 226



 Score = 32.7 bits (73), Expect = 0.65
 Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 5/130 (3%)

Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
           +  VR  +A  Y C+ +   GP    ++  T+ +     + +       A  E+   + C
Sbjct: 288 LTQVRPRNAGIYRCIGQGQRGPPI--ILEATLHLAEIEDMPLFEPRVFTAGSEE--RVTC 343

Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS-LTEEHSGNYSCEANNGLGAQRSE 288
              +G P    W+ H  + L +       G    L+ + E  +G Y+C A N  G +R +
Sbjct: 344 LPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQD 403

Query: 289 AVTLNFTVPT 298
                 TVP+
Sbjct: 404 VNITVATVPS 413


>gi|156564390 carcinoembryonic antigen-related cell adhesion
           molecule 20 4L [Homo sapiens]
          Length = 503

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 31/321 (9%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQ---INVHRVP-VADVSLETQPPGG---Q 123
           L I  + +ED+G+Y CEA+      L S+RS    ++V   P   ++ LE+    G   +
Sbjct: 123 LTILIVQREDSGTYQCEAR----DALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVE 178

Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
           VMEG  +  +           + W+       L        T  + I +V       Y C
Sbjct: 179 VMEGSSMTFLAE-TKSHPPCAYTWF-------LLDSILSHTTRTFTIHAVSREHEGLYRC 230

Query: 184 VAENGYGPSPSGLVSI-TVRIPVSRPILMLR-APRAQAAVEDV--LELHCEALRGSPPIL 239
           +  N    S + L S+ T+++ V   + M +  P +   VE+   ++L C+ +  S  + 
Sbjct: 231 LVSN----SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQ 286

Query: 240 YWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP- 297
           ++   + +        S    +  +  L    +G Y+CE  N     RSE + L    P 
Sbjct: 287 WFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQ 346

Query: 298 TGARSNHLTSGVIEGLLSTLGPATVALLFCY-GLKRKIGRRSARDPLRSLPSPLPQEFTY 356
           + + S+   +G++ G+L+ +  A+    F Y    R+  R++  DP      P+P+E  +
Sbjct: 347 SSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKE-EH 405

Query: 357 LNSPTPGQLQPIYENVNVVSG 377
              P+   L P Y N++ + G
Sbjct: 406 PTEPSSESLSPEYCNISQLQG 426


>gi|156564388 carcinoembryonic antigen-related cell adhesion
           molecule 20 4S [Homo sapiens]
          Length = 491

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 31/321 (9%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQ---INVHRVP-VADVSLETQPPGG---Q 123
           L I  + +ED+G+Y CEA+      L S+RS    ++V   P   ++ LE+    G   +
Sbjct: 123 LTILIVQREDSGTYQCEAR----DALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVE 178

Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
           VMEG  +  +           + W+       L        T  + I +V       Y C
Sbjct: 179 VMEGSSMTFLAE-TKSHPPCAYTWF-------LLDSILSHTTRTFTIHAVSREHEGLYRC 230

Query: 184 VAENGYGPSPSGLVSI-TVRIPVSRPILMLR-APRAQAAVEDV--LELHCEALRGSPPIL 239
           +  N    S + L S+ T+++ V   + M +  P +   VE+   ++L C+ +  S  + 
Sbjct: 231 LVSN----SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQ 286

Query: 240 YWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP- 297
           ++   + +        S    +  +  L    +G Y+CE  N     RSE + L    P 
Sbjct: 287 WFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQ 346

Query: 298 TGARSNHLTSGVIEGLLSTLGPATVALLFCY-GLKRKIGRRSARDPLRSLPSPLPQEFTY 356
           + + S+   +G++ G+L+ +  A+    F Y    R+  R++  DP      P+P+E  +
Sbjct: 347 SSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKE-EH 405

Query: 357 LNSPTPGQLQPIYENVNVVSG 377
              P+   L P Y N++ + G
Sbjct: 406 PTEPSSESLSPEYCNISQLQG 426


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 16/224 (7%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +L+IA    ED G+Y C A+  A   +   R  + V  V      +E   P     EG  
Sbjct: 2810 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 2863

Query: 130  LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
              L C  A G+ +    W K G      + K     + E  + ++   DA  Y C AEN 
Sbjct: 2864 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 2922

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
             G +   +    + +PV   +   R+ R    + D L L C A RGSP P + W  ++  
Sbjct: 2923 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 2977

Query: 248  TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
                 S   GG      +++ E SG Y C A N +G  R++AV+
Sbjct: 2978 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVS 3019



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 68/245 (27%), Positives = 94/245 (38%), Gaps = 25/245 (10%)

Query: 61   LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
            L       P LQ+ A+   D+G+Y C A + A +    R  Q+ V   P  + S   QP 
Sbjct: 2257 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 2312

Query: 121  GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
               +  G  + L+C  A GT      W+K    L       R+         +R  DA  
Sbjct: 2313 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 2365

Query: 181  YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
            Y C+AE     SP+G +  + R+ V  P  I+  R PR         L L C       P
Sbjct: 2366 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 2420

Query: 238  ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
             + W  H D  +    A    P  G      +L+   SG+YSC A N  G+         
Sbjct: 2421 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 2478

Query: 294  FTVPT 298
             TVPT
Sbjct: 2479 HTVPT 2483



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 61/246 (24%), Positives = 93/246 (37%), Gaps = 19/246 (7%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
            LQ AA+ +ED+G+Y C A+    +      S ++V   PV      S   +P GG +   
Sbjct: 2991 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 3046

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
                L C V  G       W K  + L       +       I      DA +Y C+AEN
Sbjct: 3047 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 3101

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G +      + + +  S P+  +          D + L C+A     P + W      
Sbjct: 3102 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 3157

Query: 248  TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
               SR   +    S  L   E   +G Y C A+N LG+  + A  +    P G+  +   
Sbjct: 3158 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS--M 3215

Query: 307  SGVIEG 312
            +GVI G
Sbjct: 3216 TGVING 3221



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)

Query: 82   GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
            G+Y CE   +      S+  Q+ VH  P   ++   +PP    +  D +  +   A G  
Sbjct: 1040 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 1095

Query: 142  DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
              T  W +        +GL LQ++ Q        +   + +   +Y CVAEN  G +   
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 1150

Query: 196  LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
               ++V +P      +       AA+   L L CEA+   PP + WF  E+ ++ G  + 
Sbjct: 1151 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 1209

Query: 255  PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
               GG    ++ T+E  SG YSC A+N  G  R
Sbjct: 1210 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 1242



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 65/256 (25%), Positives = 96/256 (37%), Gaps = 26/256 (10%)

Query: 65  WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
           +S  P LQI  +   D G Y C A  +A +  R    ++ V        ++E  P    V
Sbjct: 653 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 706

Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
           +E   + L C +A G       W+KG   ++       S+      I   + SDA  Y C
Sbjct: 707 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 765

Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
           VA N  G +    +   +R+ V   I +  +      V   + L C A     P L W  
Sbjct: 766 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 822

Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
                 G+  +P+G        GG    L S     SG YSC A + +G  R + V L  
Sbjct: 823 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQV 876

Query: 295 TVPTGARSNHLTSGVI 310
            +P       L   V+
Sbjct: 877 HMPPSILGEELNVSVV 892



 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 77/291 (26%), Positives = 109/291 (37%), Gaps = 37/291 (12%)

Query: 32   SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
            +PV LTC       P +  S A  Q        A G G+  SP   L+I        G Y
Sbjct: 2681 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 2734

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C A+  A   +  +   + V   PV    ++  P   + +  + ++L C  A G    T
Sbjct: 2735 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2787

Query: 145  FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
              W K  + +     TQ     +  I      DA  Y C+A+N  G S  G   + V++P
Sbjct: 2788 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 2846

Query: 205  VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
               P++    P           L C+A RGSP P + W        G+       PSG  
Sbjct: 2847 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2902

Query: 260  ASFNLSLTEEHSGNYSCEANNGLGAQRSEA-----VTLNFTVPTGARSNHL 305
               NL    + +G Y+C A N +G  R        V   FT   G RS  L
Sbjct: 2903 LVKNLE--GQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL 2951



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 35/240 (14%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV------ 124
            LQI    KED G Y C       + ++      N H   +   S+    P G+V      
Sbjct: 1406 LQILNAQKEDAGQYTCVVTNELGEAVK------NYHVEVLIPPSISKDDPLGEVGVKEVK 1459

Query: 125  -MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYY 182
                  L L C  +      T  WYK    +   S+ Q        +I   + SD+ +Y 
Sbjct: 1460 TKVNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 1518

Query: 183  CVAENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE-------- 226
            CVA N  G        +    P+ + +        ++ R   A+  V +  E        
Sbjct: 1519 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY 1578

Query: 227  LHCEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
            L+C+     PP L W Y ED  ++ G   +   GG    + L   E++G YSC+A+N +G
Sbjct: 1579 LYCDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1637



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
            +P EL L       T G+P+ L C          Q    + +D +AL    ++S   ++ 
Sbjct: 2310 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 2358

Query: 75   AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
             +   D G Y C A++ A  + +S R ++      V        P G + + G    +LV
Sbjct: 2359 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 2409

Query: 132  LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
            L CSV A     IT  W++  + L   + TQ      + ++ ++  +D+  Y C A N  
Sbjct: 2410 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 2466

Query: 190  GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
                +G  S+  R+ +   P +    P    +V     L C+A     P++ W   + + 
Sbjct: 2467 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 2521

Query: 249  LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
            L  RS      P G   S  +  +  + +G+Y C A+N  G+ R
Sbjct: 2522 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 2562



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 20/249 (8%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +L+I      D G Y C+   +A + +R+    +   +VP    + +T+      + G  
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV---QVPPTFENPKTETV--SQVAGSP 1950

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA---EYEIPSVRESDAEQYYCVAE 186
            LVL C V+ G    T  W K    + ++S     + +     ++  ++ + A  Y CVAE
Sbjct: 1951 LVLTCDVS-GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 2007

Query: 187  NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
            N    +    V   +  P  R   + R        E  + L CEA    PP + W   + 
Sbjct: 2008 NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQE--VRLDCEADGQPPPDVAWL-KDG 2064

Query: 247  ITLGSRSAPS-----GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
              LG    P       GG+     L    +G Y+C A+N  G + +   T+N  VP   +
Sbjct: 2065 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVPPTIK 2123

Query: 302  SNHLTSGVI 310
                 SG +
Sbjct: 2124 QGADGSGTL 2132



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)

Query: 70  KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
           +LQ+      D G Y C+A        ++ R  + V   P        +P   + + G  
Sbjct: 366 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 422

Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
           + L C VA G    T  W+    GL +    +  L  +     + S  E+ +  Y CVA 
Sbjct: 423 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 479

Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
           +   P+   ++  +V + V   +L+     +    V   LEL C+A     P + W  + 
Sbjct: 480 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 536

Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
              E++  G + A  G   + ++   E +HSG ++C+A N  G   +E
Sbjct: 537 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 581



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 66/280 (23%), Positives = 105/280 (37%), Gaps = 19/280 (6%)

Query: 30   EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
            E +P  L C    +   D      ++R+ + L  G   S       LQI  +  E+ G Y
Sbjct: 1573 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 1628

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C+A     +       ++ V   PV     E       V     + L C  A+G    T
Sbjct: 1629 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 1685

Query: 145  FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
              W +  +  +   + Q     +  ++ +   +DA  Y CVAEN  G   S     T+R+
Sbjct: 1686 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 1742

Query: 204  PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
             V   I  L   +  A +   + L C+      P + W+   + ++LG       G  + 
Sbjct: 1743 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1802

Query: 263  NLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
             L       SG Y+CEA N  G  + + V L+  VP   R
Sbjct: 1803 QLGRARLSDSGMYTCEALNAAGRDQ-KLVQLSVLVPPAFR 1841



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 63/277 (22%), Positives = 117/277 (42%), Gaps = 21/277 (7%)

Query: 31   GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
            GSP+ LTC +  + +    + +     ++ A+    S   +LQ++ +     G+Y C A+
Sbjct: 1948 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 2007

Query: 90   TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
               ++  +     + V  R+  + V+ E       V+EG  + L C        D+ +L 
Sbjct: 2008 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 2062

Query: 148  YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
                +G ++    +  L      +  +R SDA  Y CVA N  G   + L ++ V +P  
Sbjct: 2063 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 2119

Query: 207  RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
             P +   A  +   V    +++ + C  +RGSPPI   +  +   + L  R+   G G +
Sbjct: 2120 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 2177

Query: 262  FNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
              +S  +   +G ++C A +  G       TL   VP
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAGV-ADRNFTLQVQVP 2213


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 16/224 (7%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +L+IA    ED G+Y C A+  A   +   R  + V  V      +E   P     EG  
Sbjct: 2719 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 2772

Query: 130  LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
              L C  A G+ +    W K G      + K     + E  + ++   DA  Y C AEN 
Sbjct: 2773 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 2831

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
             G +   +    + +PV   +   R+ R    + D L L C A RGSP P + W  ++  
Sbjct: 2832 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 2886

Query: 248  TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
                 S   GG      +++ E SG Y C A N +G  R++AV+
Sbjct: 2887 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVS 2928



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 68/245 (27%), Positives = 94/245 (38%), Gaps = 25/245 (10%)

Query: 61   LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
            L       P LQ+ A+   D+G+Y C A + A +    R  Q+ V   P  + S   QP 
Sbjct: 2166 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 2221

Query: 121  GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
               +  G  + L+C  A GT      W+K    L       R+         +R  DA  
Sbjct: 2222 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 2274

Query: 181  YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
            Y C+AE     SP+G +  + R+ V  P  I+  R PR         L L C       P
Sbjct: 2275 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 2329

Query: 238  ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
             + W  H D  +    A    P  G      +L+   SG+YSC A N  G+         
Sbjct: 2330 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 2387

Query: 294  FTVPT 298
             TVPT
Sbjct: 2388 HTVPT 2392



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 61/246 (24%), Positives = 93/246 (37%), Gaps = 19/246 (7%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
            LQ AA+ +ED+G+Y C A+    +      S ++V   PV      S   +P GG +   
Sbjct: 2900 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 2955

Query: 128  DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
                L C V  G       W K  + L       +       I      DA +Y C+AEN
Sbjct: 2956 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAEN 3010

Query: 188  GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
              G +      + + +  S P+  +          D + L C+A     P + W      
Sbjct: 3011 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 3066

Query: 248  TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
               SR   +    S  L   E   +G Y C A+N LG+  + A  +    P G+  +   
Sbjct: 3067 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS--M 3124

Query: 307  SGVIEG 312
            +GVI G
Sbjct: 3125 TGVING 3130



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)

Query: 82   GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
            G+Y CE   +      S+  Q+ VH  P   ++   +PP    +  D +  +   A G  
Sbjct: 949  GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 1004

Query: 142  DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
              T  W +        +GL LQ++ Q        +   + +   +Y CVAEN  G +   
Sbjct: 1005 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 1059

Query: 196  LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
               ++V +P      +       AA+   L L CEA+   PP + WF  E+ ++ G  + 
Sbjct: 1060 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 1118

Query: 255  PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
               GG    ++ T+E  SG YSC A+N  G  R
Sbjct: 1119 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 1151



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 65/256 (25%), Positives = 96/256 (37%), Gaps = 26/256 (10%)

Query: 65  WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
           +S  P LQI  +   D G Y C A  +A +  R    ++ V        ++E  P    V
Sbjct: 562 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 615

Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
           +E   + L C +A G       W+KG   ++       S+      I   + SDA  Y C
Sbjct: 616 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 674

Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
           VA N  G +    +   +R+ V   I +  +      V   + L C A     P L W  
Sbjct: 675 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 731

Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
                 G+  +P+G        GG    L S     SG YSC A + +G  R + V L  
Sbjct: 732 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQV 785

Query: 295 TVPTGARSNHLTSGVI 310
            +P       L   V+
Sbjct: 786 HMPPSILGEELNVSVV 801



 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 77/291 (26%), Positives = 109/291 (37%), Gaps = 37/291 (12%)

Query: 32   SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
            +PV LTC       P +  S A  Q        A G G+  SP   L+I        G Y
Sbjct: 2590 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 2643

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C A+  A   +  +   + V   PV    ++  P   + +  + ++L C  A G    T
Sbjct: 2644 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2696

Query: 145  FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
              W K  + +     TQ     +  I      DA  Y C+A+N  G S  G   + V++P
Sbjct: 2697 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 2755

Query: 205  VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
               P++    P           L C+A RGSP P + W        G+       PSG  
Sbjct: 2756 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2811

Query: 260  ASFNLSLTEEHSGNYSCEANNGLGAQRSEA-----VTLNFTVPTGARSNHL 305
               NL    + +G Y+C A N +G  R        V   FT   G RS  L
Sbjct: 2812 LVKNLE--GQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL 2860



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 66/268 (24%), Positives = 106/268 (39%), Gaps = 23/268 (8%)

Query: 30   EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS--SPK---LQIAAMWKEDTGSY 84
            +G    L C +    +   Q +  +F+D R L  G +   SP    LQ+        G Y
Sbjct: 1177 DGQTAHLMCNV----TGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232

Query: 85   WCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLIC-SVAMGTGD 142
             C A     +  +++  Q++V   P +   + ++      V   + + LIC ++A  + +
Sbjct: 1233 SCIAANAVGE--KTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 1290

Query: 143  ITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITV 201
            IT  W K           Q    T   +I + ++ DA QY CV  N  G +      + V
Sbjct: 1291 IT--WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNY-HVEV 1347

Query: 202  RIPVS----RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH-EDITLGSRSAPS 256
             IP S     P+  +     +  V   L L CE+    PP + W+   + +T  SR    
Sbjct: 1348 LIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVL 1407

Query: 257  GGGASFNLSLTE-EHSGNYSCEANNGLG 283
            G G    +  T+   SG Y C A N  G
Sbjct: 1408 GEGRLLQIQPTQVSDSGRYLCVATNVAG 1435



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 56/238 (23%), Positives = 94/238 (39%), Gaps = 31/238 (13%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRV-----PVADVSLETQPPGGQVM 125
            LQI    KED G Y C       + +++   ++ +        P+A+V ++      +  
Sbjct: 1315 LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEV----KTK 1370

Query: 126  EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCV 184
                L L C  +      T  WYK    +   S+ Q        +I   + SD+ +Y CV
Sbjct: 1371 VNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 1429

Query: 185  AENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE--------LH 228
            A N  G        +    P+ + +        ++ R   A+  V +  E        L+
Sbjct: 1430 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1489

Query: 229  CEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
            C+     PP L W Y ED  ++ G   +   GG    + L   E++G YSC+A+N +G
Sbjct: 1490 CDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1546



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
            +P EL L       T G+P+ L C          Q    + +D +AL    ++S   ++ 
Sbjct: 2219 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 2267

Query: 75   AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
             +   D G Y C A++ A  + +S R ++      V        P G + + G    +LV
Sbjct: 2268 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 2318

Query: 132  LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
            L CSV A     IT  W++  + L   + TQ      + ++ ++  +D+  Y C A N  
Sbjct: 2319 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 2375

Query: 190  GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
                +G  S+  R+ +   P +    P    +V     L C+A     P++ W   + + 
Sbjct: 2376 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 2430

Query: 249  LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
            L  RS      P G   S  +  +  + +G+Y C A+N  G+ R
Sbjct: 2431 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 2471



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 20/249 (8%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            +L+I      D G Y C+   +A + +R+    +   +VP    + +T+      + G  
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV---QVPPTFENPKTETV--SQVAGSP 1859

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA---EYEIPSVRESDAEQYYCVAE 186
            LVL C V+ G    T  W K    + ++S     + +     ++  ++ + A  Y CVAE
Sbjct: 1860 LVLTCDVS-GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 1916

Query: 187  NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
            N    +    V   +  P  R   + R        E  + L CEA    PP + W   + 
Sbjct: 1917 NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQE--VRLDCEADGQPPPDVAWL-KDG 1973

Query: 247  ITLGSRSAPS-----GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
              LG    P       GG+     L    +G Y+C A+N  G + +   T+N  VP   +
Sbjct: 1974 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVPPTIK 2032

Query: 302  SNHLTSGVI 310
                 SG +
Sbjct: 2033 QGADGSGTL 2041



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)

Query: 70  KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
           +LQ+      D G Y C+A        ++ R  + V   P        +P   + + G  
Sbjct: 275 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 331

Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
           + L C VA G    T  W+    GL +    +  L  +     + S  E+ +  Y CVA 
Sbjct: 332 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 388

Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
           +   P+   ++  +V + V   +L+     +    V   LEL C+A     P + W  + 
Sbjct: 389 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 445

Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
              E++  G + A  G   + ++   E +HSG ++C+A N  G   +E
Sbjct: 446 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 490



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 66/280 (23%), Positives = 105/280 (37%), Gaps = 19/280 (6%)

Query: 30   EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
            E +P  L C    +   D      ++R+ + L  G   S       LQI  +  E+ G Y
Sbjct: 1482 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 1537

Query: 85   WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
             C+A     +       ++ V   PV     E       V     + L C  A+G    T
Sbjct: 1538 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 1594

Query: 145  FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
              W +  +  +   + Q     +  ++ +   +DA  Y CVAEN  G   S     T+R+
Sbjct: 1595 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 1651

Query: 204  PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
             V   I  L   +  A +   + L C+      P + W+   + ++LG       G  + 
Sbjct: 1652 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1711

Query: 263  NLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGAR 301
             L       SG Y+CEA N  G  + + V L+  VP   R
Sbjct: 1712 QLGRARLSDSGMYTCEALNAAGRDQ-KLVQLSVLVPPAFR 1750



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 63/277 (22%), Positives = 117/277 (42%), Gaps = 21/277 (7%)

Query: 31   GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
            GSP+ LTC +  + +    + +     ++ A+    S   +LQ++ +     G+Y C A+
Sbjct: 1857 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 1916

Query: 90   TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
               ++  +     + V  R+  + V+ E       V+EG  + L C        D+ +L 
Sbjct: 1917 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 1971

Query: 148  YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
                +G ++    +  L      +  +R SDA  Y CVA N  G   + L ++ V +P  
Sbjct: 1972 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 2028

Query: 207  RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
             P +   A  +   V    +++ + C  +RGSPPI   +  +   + L  R+   G G +
Sbjct: 2029 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 2086

Query: 262  FNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
              +S  +   +G ++C A +  G       TL   VP
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAGV-ADRNFTLQVQVP 2122


>gi|224994173 roundabout 1 isoform d [Homo sapiens]
          Length = 1551

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)

Query: 78  KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           + D G Y C A+    + +    S      V +        P    V  G+  V+ C   
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
            G  + T  W K    L+ + +       +  I   R+SDA +Y CV  N  G   S + 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215

Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
            +TV   + RP  + R       V+D  E  CEA RG P P + W   +     SR    
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271

Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
                    +T    G+Y+C A N +G   + A     TV  G+   H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L+I  +   D GSY C A+ M  K   S    + V   P   V      P  QV+   R 
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331

Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
           V     A G       W + G+  L          S+   S T +  I +V+ SD   Y 
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
           C   N  G       + +T  I    P ++ + P  Q  AV+    L C A     P + 
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451

Query: 241 W 241
           W
Sbjct: 452 W 452



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)

Query: 66  SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
           S +  L I  + + D G Y C+   +A  ++   ++ + V  V +AD    +  Q P  Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428

Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
            +  D   ++  VA G+   T LW K  V ++ Q S+ ++      +I   +  D  +Y 
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488

Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
           C+A      +PSG  + +  I V    + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517


>gi|224994171 roundabout 1 isoform c [Homo sapiens]
          Length = 1606

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)

Query: 78  KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           + D G Y C A+    + +    S      V +        P    V  G+  V+ C   
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
            G  + T  W K    L+ + +       +  I   R+SDA +Y CV  N  G   S + 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215

Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
            +TV   + RP  + R       V+D  E  CEA RG P P + W   +     SR    
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271

Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
                    +T    G+Y+C A N +G   + A     TV  G+   H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L+I  +   D GSY C A+ M  K   S    + V   P   V      P  QV+   R 
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331

Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
           V     A G       W + G+  L          S+   S T +  I +V+ SD   Y 
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
           C   N  G       + +T  I    P ++ + P  Q  AV+    L C A     P + 
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451

Query: 241 W 241
           W
Sbjct: 452 W 452



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)

Query: 66  SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
           S +  L I  + + D G Y C+   +A  ++   ++ + V  V +AD    +  Q P  Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428

Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
            +  D   ++  VA G+   T LW K  V ++ Q S+ ++      +I   +  D  +Y 
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488

Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
           C+A      +PSG  + +  I V    + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 77/326 (23%), Positives = 128/326 (39%), Gaps = 29/326 (8%)

Query: 6    LLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW 65
            ++++ A    P  + + +S    TEG  + L C +    +  A  Q  ++R   +L P  
Sbjct: 2040 VVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVV----AGSAHAQVTWYRRGGSLPPHT 2095

Query: 66   S-SSPKLQIAAMWKEDTGSYWCEAQ--------TMASKVLRSRRSQINVHRVPVADVSLE 116
                 +L++  +   D+G Y C  +        ++   VL    S  +   VP +   + 
Sbjct: 2096 QVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIR 2155

Query: 117  TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
             +P    V EG  L L C V  G       W+K    L  + +T  SL   ++   V  +
Sbjct: 2156 IEPSSSHVAEGQTLDLNC-VVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQ---VTPA 2211

Query: 177  DAEQYYCVAENGYGP-SPSGLVSITVR-IPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
            D+ +Y C      GP   S LV+I    IP   P + + +  +  A    L+L C     
Sbjct: 2212 DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2271

Query: 235  SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT--- 291
            +   + W Y    +L +R    G    +    +   +G Y C A+NG+ A  +  VT   
Sbjct: 2272 AHAQVTW-YKRGGSLPARHQVRGSRL-YIFQASPADAGQYVCRASNGMEASITVTVTGTQ 2329

Query: 292  -LNFTVPTGA----RSNHLTSGVIEG 312
              N   P G+    R    +S V EG
Sbjct: 2330 GANLAYPAGSTQPIRIEPSSSQVAEG 2355



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 65/278 (23%), Positives = 109/278 (39%), Gaps = 20/278 (7%)

Query: 23   ASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-SSPKLQIAAMWKEDT 81
            +S S   EG  + L C    L +  A  Q  + +   +L         +L++  +   D+
Sbjct: 2443 SSSSQVAEGQTLDLNC----LVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADS 2498

Query: 82   GSYWCE----AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
            G Y C     + T  + VL + + +++          +  +     +  G  L L C VA
Sbjct: 2499 GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA 2558

Query: 138  MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
                  T  WYK   G +L S+ Q  + +   IP V  +D+ +Y C   NG G   + L+
Sbjct: 2559 -SQAPHTITWYKR--GGSLPSRHQ-IVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLI 2614

Query: 198  -----SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
                 S +  +P   P + + +          L+L+C   R    I+ W Y    +L SR
Sbjct: 2615 VTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITW-YKRGGSLPSR 2673

Query: 253  SAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
                G     +  ++   SG Y C ANN + A  +  V
Sbjct: 2674 HQTHGSHLRLH-QMSVADSGEYVCRANNNIDALEASIV 2710



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 59/239 (24%), Positives = 94/239 (39%), Gaps = 25/239 (10%)

Query: 62   GPGWSSSPKLQI-------AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS 114
            GPG     K QI        A+   D   Y C A + A + +   R+ ++VH        
Sbjct: 1902 GPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVA--RAVLHVHGG--GGPR 1957

Query: 115  LETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVR 174
            ++  P   QV  G  + L C  A G    T  W K    L  Q++++R+  A   IP++ 
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAA-GVPSATITWRKEGGSLPPQARSERTDIATLLIPAIT 2016

Query: 175  ESDAEQYYCVAENGYGPSPSGLVSITVRIPV------SRPILMLRAPRAQAAVEDVLELH 228
             +DA  Y CVA      SP+G     +++ V      S P + + +          L+L+
Sbjct: 2017 TADAGFYLCVA-----TSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLN 2071

Query: 229  CEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
            C  + GS      +Y    +L   +   G        ++   SG Y C   NG G + +
Sbjct: 2072 C-VVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLP-QVSPADSGEYVCRVENGSGPKEA 2128



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 55/223 (24%), Positives = 87/223 (39%), Gaps = 12/223 (5%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQI++    D G+Y C AQ       +     ++   +      ++ +     V  G   
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
             L CS A G+   T  W K    L  Q + +        IP V + D+ QY C A     
Sbjct: 3230 TLRCS-ATGSPAPTIHWSKLRSPLPWQHRLEGDTLI---IPRVAQQDSGQYICNA----- 3280

Query: 191  PSPSGLVSITVRIPVSRPILMLRAP-RAQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
             SP+G    T+ + V  P      P  A     + ++L C A  G+PP+ + +     +L
Sbjct: 3281 TSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLA-HGTPPLTFQWSRVGSSL 3339

Query: 250  GSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
              R+        F  +  E+ SG Y C   N +G+  + A  L
Sbjct: 3340 PGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLL 3381



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 66/262 (25%), Positives = 104/262 (39%), Gaps = 32/262 (12%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS-----LETQPPGGQVM 125
            L I A+   D G Y C A + A     + +++I V  +  +D S     +E+  P   V 
Sbjct: 2010 LLIPAITTADAGFYLCVATSPAG----TAQARIQVVVLSASDASPPPVKIESSSPS--VT 2063

Query: 126  EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
            EG  L L C VA G+      WY+    L   ++   S      +P V  +D+ +Y C  
Sbjct: 2064 EGQTLDLNCVVA-GSAHAQVTWYRRGGSLPPHTQVHGS---RLRLPQVSPADSGEYVCRV 2119

Query: 186  ENGYGPSPSGL-VSIT---------VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGS 235
            ENG GP  + + VS+            +P S   + +    +  A    L+L+C  + G 
Sbjct: 2120 ENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNC-VVPGQ 2178

Query: 236  PPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTLNF 294
                  ++    +L +R    G     +  +T   SG Y C      G  + S  VT+  
Sbjct: 2179 AHAQVTWHKRGGSLPARHQTHGSLLRLH-QVTPADSGEYVCHVVGTSGPLEASVLVTIEA 2237

Query: 295  TVPTG----ARSNHLTSGVIEG 312
            +V  G     R    +S V EG
Sbjct: 2238 SVIPGPIPPVRIESSSSTVAEG 2259



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 50/201 (24%), Positives = 87/201 (43%), Gaps = 19/201 (9%)

Query: 19   LFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRAL-GPGWSSSPKLQIAAMW 77
            +++ AS SH TEG  + L C +P      A  Q  +++   +L     +   +L++  + 
Sbjct: 2927 IYIEASSSHVTEGQTLDLNCVVP----GQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVS 2982

Query: 78   KEDTGSYWCEA------QTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
              D+G Y C A      +  AS  +    S+ + +R+    +S++  PP   V +G    
Sbjct: 2983 PADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISID--PPSSTVQQGQDAS 3040

Query: 132  LICSVAMGTGDITFLWYKGAVGL--NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGY 189
              C +  G   I+  W      L  N+      S+     I   R S+   Y CVA N Y
Sbjct: 3041 FKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIIT---IVGTRPSNHGTYRCVASNAY 3097

Query: 190  GPSPSGLVSITVRIPVSRPIL 210
            G + S +V+++V  P +  +L
Sbjct: 3098 GVAQS-VVNLSVHGPPTVSVL 3117



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 71/304 (23%), Positives = 117/304 (38%), Gaps = 28/304 (9%)

Query: 23   ASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS-SPKLQIAAMWKEDT 81
            +S SH  EG  + L C +P      A  Q  + +   +L     +   +L++  +   D+
Sbjct: 2733 SSSSHVAEGETLDLNCVVP----GQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADS 2788

Query: 82   GSYWCEAQTM-----ASKVLRSRRSQINVHRVPVADVS--LETQPPGGQVMEGDRLVLIC 134
            G Y C          AS ++    S  +   VP    +  +  +P   +V EG  L L C
Sbjct: 2789 GEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKC 2848

Query: 135  SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGP-SP 193
             V  G       W+K    L  + +    L     +  V  +D+ +Y C      G    
Sbjct: 2849 -VVPGQAHAQVTWHKRGGNLPARHQVHGPLL---RLNQVSPADSGEYSCQVTGSSGTLEA 2904

Query: 194  SGLVSITVRIPVSRPI------LMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
            S LV+I    P   P       + + A  +       L+L+C  + G       +Y    
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VVPGQAHAQVTWYKRGG 2963

Query: 248  TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH-LT 306
            +L +R    G     +L ++   SG Y C A +G G ++  + T+  TVP    S++ L 
Sbjct: 2964 SLPARHQTHGSQLRLHL-VSPADSGEYVCRAASGPGPEQEASFTV--TVPPSEGSSYRLR 3020

Query: 307  SGVI 310
            S VI
Sbjct: 3021 SPVI 3024



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 66/264 (25%), Positives = 105/264 (39%), Gaps = 28/264 (10%)

Query: 31   GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-SSPKLQIAAMWKEDTGSYWCEAQ 89
            G+ V   C +P    SD   Q  +F++   L PG S     L+I  + +   G+Y C+A 
Sbjct: 3414 GASVEFHCAVP----SDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAH 3469

Query: 90   TMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYK 149
                K   S  +Q+ +  +P   +++ T      V+ G  +   C +A+G       W K
Sbjct: 3470 GPWGKAQAS--AQLVIQALPSVLINIRTSVQ--TVVVGHAVEFEC-LALGDPKPQVTWSK 3524

Query: 150  GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPI 209
              VG +L+    +S      I  V  +DA QY C A N  G + S ++ +   +P     
Sbjct: 3525 --VGGHLRPGIVQS-GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMP 3581

Query: 210  LMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNL----S 265
              +R P   AAV       C A     P + W   +       S P       N+    S
Sbjct: 3582 QEVRVPAGSAAV-----FPCIASGYPTPDISWSKLDG------SLPPDSRLENNMLMLPS 3630

Query: 266  LTEEHSGNYSCEANNGLGAQRSEA 289
            +  + +G Y C A N  G  ++ A
Sbjct: 3631 VRPQDAGTYVCTATNRQGKVKAFA 3654



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 58/289 (20%), Positives = 107/289 (37%), Gaps = 17/289 (5%)

Query: 10   CAPLCEPAELFLIASPSHPT--EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS 67
            C P    A L +   P+     +G   +L C++     S   + +    D R +  G   
Sbjct: 1668 CLPETNQAPLVVEVHPARSIVPQGGSHSLRCQV---SGSPPHYFYWSREDGRPVPSGTQQ 1724

Query: 68   ---SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ- 123
                 +L   ++   D G Y C  + +      + R+++ V   P   +++  +    Q 
Sbjct: 1725 RHQGSELHFPSVQPSDAGVYICTCRNLHQS--NTSRAELLVTEAPSKPITVTVEEQRSQS 1782

Query: 124  VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
            V  G  +  IC+    +   T +W +   G  L ++          I +V+ SDA  Y C
Sbjct: 1783 VRPGADVTFICTAKSKSPAYTLVWTRLHNG-KLPTRAM-DFNGILTIRNVQLSDAGTYVC 1840

Query: 184  VAENGYGPSPSGLVSITVRIP--VSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
               N +     G  ++ V+    +S P++ +  P+       + E  C A     P L W
Sbjct: 1841 TGSNMFAMD-QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899

Query: 242  FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
                   L +++   GG      ++       Y C A++  G Q + AV
Sbjct: 1900 TGGPGGQLPAKAQIHGGILRLP-AVEPTDQAQYLCRAHSSAGQQVARAV 1947



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 15/167 (8%)

Query: 82   GSYWCEAQTMASKVLRSRRSQIN--VHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
            G+Y C    +AS      +S +N  VH  P   V     P G   ++  + V +  V+ G
Sbjct: 3087 GTYRC----VASNAYGVAQSVVNLSVHGPPTVSVL----PEGPVWVKVGKAVTLECVSAG 3138

Query: 140  TGDITFLWYK-GAVGLNLQSKTQRSLT--AEYEIPSVRESDAEQYYCVAENGYGPSPSGL 196
                +  W +  +    L+ +T   +   A  +I S + SDA  Y C+A+N  G +   +
Sbjct: 3139 EPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQV 3198

Query: 197  VSITVRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPILYW 241
              I     ++     ++A  A+  VE      L C A     P ++W
Sbjct: 3199 EVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW 3245



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 45/230 (19%), Positives = 78/230 (33%), Gaps = 22/230 (9%)

Query: 79   EDTGSYWCE-------AQTMASKVLRSRRSQINVHRVPVADV-SLETQPPGGQVMEGDRL 130
            ED+G Y C        A+  A  +++     +    +P     +++  P       G  +
Sbjct: 3358 EDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASV 3417

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
               C+V    G     W+K    L      Q  +     I ++ +S    Y C A   +G
Sbjct: 3418 EFHCAVPSDRGT-QLRWFKEGGQLPPGHSVQDGVL---RIQNLDQSCQGTYICQAHGPWG 3473

Query: 191  PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLG 250
             + +    +   +P    ++ +R       V   +E  C AL    P + W       +G
Sbjct: 3474 KAQASAQLVIQALP--SVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWS-----KVG 3526

Query: 251  SRSAPS---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
                P     GG      +    +G Y C A N  G  +S  + L   +P
Sbjct: 3527 GHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3576



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 21/156 (13%)

Query: 218 QAAVEDVLELHCEALRGSPPILYWFY-------HEDITLGSRSAPSGGGASFNLSLTEEH 270
           QA+    +   C A+    PI+ W         H  +T+ S     G G      + E  
Sbjct: 417 QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEG---GRGTLIIRDVKESD 473

Query: 271 SGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVI-EGLLSTLGPATVALLFCYG 329
            G Y+CEA N  G        + F +P G        G   +G       A     FC+G
Sbjct: 474 QGAYTCEAMNARG--------MVFGIPDGVLELVPQRGPCPDGHFYLEHSAACLPCFCFG 525

Query: 330 LKRKI-GRRSARDPLRSLPSPLPQEFTYLNSPTPGQ 364
           +       R  RD +R L    P +F  +N   P Q
Sbjct: 526 ITSVCQSTRRFRDQIR-LRFDQPDDFKGVNVTMPAQ 560


>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
           sapiens]
          Length = 1562

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)

Query: 78  KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           + D G Y C A+    + +    S      V +        P    V  G+  V+ C   
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
            G  + T  W K    L+ + +       +  I   R+SDA +Y CV  N  G   S + 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215

Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
            +TV   + RP  + R       V+D  E  CEA RG P P + W   +     SR    
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271

Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
                    +T    G+Y+C A N +G   + A     TV  G+   H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L+I  +   D GSY C A+ M  K   S    + V   P   V      P  QV+   R 
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331

Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
           V     A G       W + G+  L          S+   S T +  I +V+ SD   Y 
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
           C   N  G       + +T  I    P ++ + P  Q  AV+    L C A     P + 
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451

Query: 241 W 241
           W
Sbjct: 452 W 452



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)

Query: 66  SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
           S +  L I  + + D G Y C+   +A  ++   ++ + V  V +AD    +  Q P  Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428

Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
            +  D   ++  VA G+   T LW K  V ++ Q S+ ++      +I   +  D  +Y 
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488

Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
           C+A      +PSG  + +  I V    + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517


>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
           sapiens]
          Length = 1615

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 58/228 (25%), Positives = 85/228 (37%), Gaps = 12/228 (5%)

Query: 78  KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           + D G Y C A+    + +    S      V +        P    V  G+  V+ C   
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
            G  + T  W K    L+ + +       +  I   R+SDA +Y CV  N  G   S + 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215

Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
            +TV   + RP  + R       V+D  E  CEA RG P P + W   +     SR    
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271

Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNH 304
                    +T    G+Y+C A N +G   + A     TV  G+   H
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA---TLTVQVGSEPPH 316



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)

Query: 71  LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
           L+I  +   D GSY C A+ M  K   S    + V   P   V      P  QV+   R 
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331

Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
           V     A G       W + G+  L          S+   S T +  I +V+ SD   Y 
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
           C   N  G       + +T  I    P ++ + P  Q  AV+    L C A     P + 
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451

Query: 241 W 241
           W
Sbjct: 452 W 452



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)

Query: 66  SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
           S +  L I  + + D G Y C+   +A  ++   ++ + V  V +AD    +  Q P  Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428

Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
            +  D   ++  VA G+   T LW K  V ++ Q S+ ++      +I   +  D  +Y 
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488

Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
           C+A      +PSG  + +  I V    + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 59/229 (25%), Positives = 92/229 (40%), Gaps = 19/229 (8%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            L I  +W  D G+Y CEA+    K+       +     P+  +S    P    V+EG +L
Sbjct: 852  LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGIS----PSVANVIEGQQL 907

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
             L C++  G       W K +  L               I  V+  D  +Y CVA N  G
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAG 967

Query: 191  ---PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV-LELHCEALRGSPPILYWFYHED 246
                + S +V +   I   + IL        + +E + + L C+A     P + W    +
Sbjct: 968  TNNKTTSVVVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGNPKPSVIWSKKGE 1019

Query: 247  ITLGSRSAPSGG--GASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
            +   S +  S G  G+ + +S   E SG Y C A N  G A+R   +T+
Sbjct: 1020 LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 70/256 (27%), Positives = 102/256 (39%), Gaps = 20/256 (7%)

Query: 33   PVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS----SSPKLQIAAMWKEDTGSYWCEA 88
            P+TL+C+   L   D  +     +D RA+         SS  LQIA +   D G Y C A
Sbjct: 4095 PITLSCEADGLPPPDITWH----KDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMA 4150

Query: 89   QTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWY 148
              +A     S  +++ VH  P     + +      V E  + +L C VA G       W 
Sbjct: 4151 ANVAGS--SSTSTKLTVHVPP----RIRSTEGHYTVNENSQAILPC-VADGIPTPAINWK 4203

Query: 149  KGAVGL-NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
            K  V L NL  K       E  + +V   D+  Y CVA N  G   +  VS+TV +    
Sbjct: 4204 KDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGED-THTVSLTVHV---L 4259

Query: 208  PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
            P              + L L C+A     P L W ++ +I      + +G        ++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVS 4319

Query: 268  EEHSGNYSCEANNGLG 283
            +E SG Y C A N +G
Sbjct: 4320 KEDSGTYVCTAENSVG 4335



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 24/232 (10%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQI+   +ED G+Y C AQ  A   L   + ++NV   PV    L+       V+  D+ 
Sbjct: 4043 LQISRAVREDAGTYMCVAQNPAGTAL--GKIKLNVQVPPVISPHLKE-----YVIAVDKP 4095

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGY 189
            + +   A G       W+K    + ++S  QR L++   +I  V+  DA  Y C+A N  
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAI-VESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 190  GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPILYWFYHEDI 247
            G S S    +TV +P       +R+      V +  +  L C A     P + W     +
Sbjct: 4155 G-SSSTSTKLTVHVPP-----RIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVL 4208

Query: 248  ---TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTV 296
                LG  +A   G      ++  E SG Y+C ANN  G    +  T++ TV
Sbjct: 4209 LANLLGKYTAEPYGELILE-NVVLEDSGFYTCVANNAAG---EDTHTVSLTV 4256



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 63/267 (23%), Positives = 103/267 (38%), Gaps = 20/267 (7%)

Query: 39  KMPFLQSSDAQFQFCFFRDTRALGPGW----SSSPKLQIAAMWKEDTGSYWCEAQTMASK 94
           ++P    S   F   F R+   LG       S+S  L IA +   D G Y C A + A  
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGT 507

Query: 95  VLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGL 154
                   ++    PV  V     P    V  G+R VL C +     D    W +    +
Sbjct: 508 GRAQTFFDVS-EPPPVIQV-----PNNVTVTPGERAVLTCLIISAV-DYNLTWQRNDRDV 560

Query: 155 NLQSKTQRSLTAEY--EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILML 212
            L    +    A    E+ SV+ +DA +Y+C+  +  G S +  V +TV+ P    ++  
Sbjct: 561 RLAEPARIRTLANLSLELKSVKFNDAGEYHCMV-SSEGGSSAASVFLTVQEPPKVTVM-- 617

Query: 213 RAPRAQAAV-EDVLELHCEALRGSPPILYWFYHEDITLGS-RSAPSGGGASFNLSLTEEH 270
             P+ Q+      + + C A     P + W  ++   +GS R   +  G  F  +   + 
Sbjct: 618 --PKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKD 675

Query: 271 SGNYSCEANNGLGAQRSEAVTLNFTVP 297
           +G Y C A+N  G  +  +       P
Sbjct: 676 AGIYGCLASNSAGTDKQNSTLRYIEAP 702



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 69/289 (23%), Positives = 109/289 (37%), Gaps = 42/289 (14%)

Query: 30   EGSPVTLTCKM--------------PFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAA 75
            EG PVTL CK                 + +S A+F                +   L + +
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA-------------GADGSLYVVS 1040

Query: 76   MWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS--LETQPPGGQVMEGDRLVLI 133
               E++G Y C A   A    R  +  + V      D     + +P    V+ G+ + L 
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLP 1100

Query: 134  CSVAMGTGDITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGYGPS 192
            C V      I   W K    ++  S     L +   +I   R SD+  Y CVA N     
Sbjct: 1101 CEVKSLPPPI-ITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN----- 1154

Query: 193  PSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSP-PILYWFYHEDITL- 249
             +G V+  V++ V  P  + R P+  +  V   +++ C A +G+P P++ W       L 
Sbjct: 1155 IAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNA-QGTPLPVITWSKGGSTMLV 1213

Query: 250  -GSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
             G     +  G       T   +G Y+C A N  G   +E +TL+   P
Sbjct: 1214 DGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETE-ITLHVQEP 1261



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 68/282 (24%), Positives = 107/282 (37%), Gaps = 34/282 (12%)

Query: 15   EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-----GWSSSP 69
            +P E+ ++A       G  VTL C++  L      +     ++T+ + P      +  S 
Sbjct: 1085 KPVEISVLA-------GEEVTLPCEVKSLPPPIITWA----KETQLISPFSPRHTFLPSG 1133

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
             ++I      D+G Y C A  +A  V  ++  ++NVH  P     ++  P   +V  G R
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNV--TQAVKLNVHVPP----KIQRGPKHLKVQVGQR 1187

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRS-LTAEYEIPSVRESDAEQYYCVAENG 188
            + + C+ A GT      W KG   + +  +   S       I     SDA  Y CVA N 
Sbjct: 1188 VDIPCN-AQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNI 1246

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV----LELHCEALRGSPPILYWFYH 244
             G   +    IT+ +     +  L  P      E V    +E  C A     P + W ++
Sbjct: 1247 AGTDET---EITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHN 1303

Query: 245  EDITLGSR---SAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
                 G     S    G      S+T   +G Y C A N  G
Sbjct: 1304 GRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 60/226 (26%), Positives = 91/226 (40%), Gaps = 12/226 (5%)

Query: 66   SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
            S   +LQI+   K D   Y C A  +A    +    Q+ +        S  T+     V 
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEII---VT 2305

Query: 126  EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY--EIPSVRESDAEQYYC 183
             G  + L C V  G    T  W K    L +++K    L   +  ++ ++  SD  +Y C
Sbjct: 2306 RGKSISLECEV-QGIPPPTVTWMKDGHPL-IKAKGVEILDEGHILQLKNIHVSDTGRYVC 2363

Query: 184  VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWF 242
            VA N  G +      ++V  P S  I   R+P   + VE + + L CEA     P + WF
Sbjct: 2364 VAVNVAGMTDKKY-DLSVHAPPSI-IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWF 2421

Query: 243  YHE-DITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQR 286
                 ++L +      GG    L   T E +G Y+C   N  G +R
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 70/245 (28%), Positives = 97/245 (39%), Gaps = 32/245 (13%)

Query: 66   SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLET--QPPGGQ 123
            SS   LQIA    ED G Y C A   A +    +  Q++VH  P    SLE   +     
Sbjct: 1878 SSGRVLQIAKTLLEDAGRYTCVATNAAGET--QQHIQLHVHEPP----SLEDAGKMLNET 1931

Query: 124  VMEGDRLVLICSVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESD 177
            V+  + + L C  A G       WYK      G+  +   ++ Q       +I S + SD
Sbjct: 1932 VLVSNPVQLECKAA-GNPVPVITWYKDNRLLSGSTSMTFLNRGQ-----IIDIESAQISD 1985

Query: 178  AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP- 236
            A  Y CVA N  G +     S+ V +    P +          V + + L CEA RG P 
Sbjct: 1986 AGIYKCVAINSAGATEL-FYSLQVHV---APSISGSNNMVAVVVNNPVRLECEA-RGIPA 2040

Query: 237  PILYWFYHEDITLGSRS----APSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
            P L W   +   + S S      SGG      S     +G Y+C A N  G ++   + L
Sbjct: 2041 PSLTWL-KDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG-EKQRDIDL 2098

Query: 293  NFTVP 297
               VP
Sbjct: 2099 RVYVP 2103



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 65/240 (27%), Positives = 87/240 (36%), Gaps = 33/240 (13%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            L I +    DTG Y C A   A      RR  + VH  P    S+   P    V+   + 
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGT--DRRRIDLQVHVPP----SIAPGPTNMTVIVNVQT 3821

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNL---QSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
             L C  A G    +  W K    LN+   Q+  +   +    I S    D   Y C   N
Sbjct: 3822 TLACE-ATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880

Query: 188  GYGPSPSGLVSITVRIPVS---RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
            G G      V +TV++P S    P   L    A A +       C A     P ++W  +
Sbjct: 3881 GAGDDKR-TVDLTVQVPPSIADEPTDFLVTKHAPAVIT------CTASGVPFPSIHWTKN 3933

Query: 245  EDITLGSRSAPSG-------GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
                 G R  P G        GA   L+    H+G Y+C A N  G+     VTL+   P
Sbjct: 3934 -----GIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRH-VTLHVHEP 3987



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 74/295 (25%), Positives = 124/295 (42%), Gaps = 37/295 (12%)

Query: 24   SPSHPTE-----GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-WSSSPKLQIAAMW 77
            S SHPTE     G  ++L C++  +      +        +A G         LQ+  + 
Sbjct: 2295 SGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH 2354

Query: 78   KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
              DTG Y C A  +A   +  ++  ++VH  P + +     P    V+E + + L C  A
Sbjct: 2355 VSDTGRYVCVAVNVAG--MTDKKYDLSVH-APPSIIGNHRSPENISVVEKNSVSLTCE-A 2410

Query: 138  MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES--DAEQYYCVAENGYGPSPSG 195
             G    +  W+K    ++L S + R L+    +  ++ +  DA QY CV  N  G     
Sbjct: 2411 SGIPLPSITWFKDGWPVSL-SNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERK- 2468

Query: 196  LVSITVRIPVSRPILMLRAPRAQAAVEDV-------LELHCEALRGSPPILYWFYHED-I 247
            +  ++V +P   P ++      +  +EDV       + L CE      P + W  H+D  
Sbjct: 2469 IFGLSVLVP---PHIV-----GENTLEDVKVKEKQSVTLTCEVTGNPVPEITW--HKDGQ 2518

Query: 248  TLGSRSAP---SGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN-FTVPT 298
             L    A    SGG      ++   H+G Y+C A++  G  +S + +LN F  PT
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG-HKSRSFSLNVFVSPT 2572



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 67/255 (26%), Positives = 98/255 (38%), Gaps = 26/255 (10%)

Query: 79  EDTGSYWCEAQTMA-SKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
           +D G Y C A   A +    S    I   ++ V    L        V  GD  V+ C  +
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSEL-------LVALGDITVMECKTS 726

Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR---SLTAEYEIPSVRESDAEQYYCVAENGYGPSPS 194
            G       W+KG   L L+  T      L    +I   ++ DA  Y CVA N  G + +
Sbjct: 727 -GIPPPQVKWFKG--DLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRA-T 782

Query: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
           G +++ V  P   P+ +         +   + L C       P + W   +++ + SR  
Sbjct: 783 GKITLDVGSP---PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPF 839

Query: 255 PSGG------GASFNLSLTEEHSGNYSCEANNGLGAQRSE-AVTLNFTVPTGARSNHLTS 307
                     GA F L+L     G Y CEA N  G  +SE  VT+   V      +   +
Sbjct: 840 SVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899

Query: 308 GVIEGLLSTLGPATV 322
            VIEG   TL P T+
Sbjct: 900 NVIEGQQLTL-PCTL 913



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 61/248 (24%), Positives = 93/248 (37%), Gaps = 20/248 (8%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            L I      D+ +Y C    +A    +S    ++V+  P+ + +L T P   QV+    L
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVAGTAEKS--FHVDVYVPPMIEGNLAT-PLNKQVVIAHSL 1659

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE-YEIPSVRESDAEQYYCVAENGY 189
             L C  A G       W K  V +      +     +  EI S +E D  QY CVA    
Sbjct: 1660 TLECKAA-GNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT--- 1715

Query: 190  GPSPSGLVSITVRIPVSRPILMLRAPRAQ---AAVEDVLELHCEALRGSPPILYWFYHED 246
              S +G   I   + V  P  +            V ++LEL C      PP + W     
Sbjct: 1716 --SVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQ 1773

Query: 247  ITLGSRSAPS---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSE-AVTLNFTVPTGARS 302
            + +  R        G           ++G Y C A N  G  + E  VT++  VP   +S
Sbjct: 1774 L-IDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH--VPPTIKS 1830

Query: 303  NHLTSGVI 310
            + L+  V+
Sbjct: 1831 SGLSERVV 1838



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 24/231 (10%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS----LETQPPGGQVME 126
            LQI    +++ G Y C A   A ++++    ++ V+  P+ +          P   ++  
Sbjct: 2631 LQILNAQEDNAGRYSCVATNEAGEMIK--HYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688

Query: 127  GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRE---SDAEQYYC 183
             + L L C  A      +  WYK   G  L+S    ++ A      ++E   SD  +Y C
Sbjct: 2689 NNTLTLECE-AYAIPSASLSWYKD--GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTC 2745

Query: 184  VAENGYGPSPSGLVSITVRIPVSRPIL-----MLRAPRAQAA----VEDVLELHCEALRG 234
            VA N  G        + +++P S   L     ML   R   A    + + + L+CE    
Sbjct: 2746 VASNIAGEDELDF-DVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAA 2804

Query: 235  SPPILYWFYH-EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
             PP L W+     +T   +     GG    +   + E +G Y+C A N  G
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/237 (24%), Positives = 97/237 (40%), Gaps = 12/237 (5%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQI     ED G Y C A   A +   S +  + V   P+   +    P    V+     
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGE--DSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSA 2890

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE--YEIPSVRESDAEQYYCVAENG 188
            ++ C ++ G+      W K    L L+    + L+     +I + + +D  +Y CVAEN 
Sbjct: 2891 LIEC-LSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITDIGRYVCVAENT 2948

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-I 247
             G S     ++ V +P S  ++  ++      V + + L CE     PP L W  +E  I
Sbjct: 2949 AG-SAKKYFNLNVHVPPS--VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPI 3005

Query: 248  TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSN 303
             L + +    GG +  +   +    G Y+C A N  G  + +  +L   VP   + +
Sbjct: 3006 KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK-FSLTVYVPPSIKDH 3061



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 62/250 (24%), Positives = 98/250 (39%), Gaps = 24/250 (9%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQI      D G Y C A   A +    ++  + V+  P              V EG  +
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGE--SKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSV 3077

Query: 131  VLIC-SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRE---SDAEQYYCVAE 186
             L C S A+    IT  WYK   G  +   T   + A+ ++  +++   SD  QY C A 
Sbjct: 3078 SLECESNAVPPPVIT--WYKN--GRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAI 3133

Query: 187  NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV---LELHCEALRGSPPILYWFY 243
            N  G        + V +P S     +  P  +  VE +   + L C+A    PP + W  
Sbjct: 3134 NVAGRDDKNF-HLNVYVPPS-----IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK 3187

Query: 244  HEDITLGSRSAPS---GGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVTLNFTVPTG 299
            +      S S       GG+   ++ ++   SGNY+C A+N +  +  +   L+  VP  
Sbjct: 3188 NHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN-MEGKAQKYYFLSIQVPPS 3246

Query: 300  ARSNHLTSGV 309
                 + S V
Sbjct: 3247 VAGAEIPSDV 3256



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 23/221 (10%)

Query: 79   EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGG-QVMEGDRLVLIC-SV 136
            ED+G Y C A   A +   +    + VH +P       T+ PG   + +G++L L C + 
Sbjct: 4232 EDSGFYTCVANNAAGE--DTHTVSLTVHVLPTF-----TELPGDVSLNKGEQLRLSCKAT 4284

Query: 137  AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGL 196
             +    +T+ +    +  +  S    S   E  I  V + D+  Y C AEN  G      
Sbjct: 4285 GIPLPKLTWTFNNNIIPAHFDSVNGHS---ELVIERVSKEDSGTYVCTAENSVG-----F 4336

Query: 197  VSITVRIPVSRPILMLRAPRAQAAVEDV---LELHCEALRGSPPILYWFYHE-DITLGSR 252
            V     + V  P +  +       +E +     L+CE      P + W     DI +  R
Sbjct: 4337 VKAIGFVYVKEPPVF-KGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR 4395

Query: 253  SAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
                G G+        E +G+Y+C A N  G  +RS ++TL
Sbjct: 4396 IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL 4436



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 63/251 (25%), Positives = 100/251 (39%), Gaps = 29/251 (11%)

Query: 80   DTGSYWCEAQTMASKVLRSRRSQINVHRVPV-----ADVSLETQPPGGQVMEGDRLVLIC 134
            D G Y C A   A +   + +  ++V   PV     ADVS+E          G  + L C
Sbjct: 766  DAGDYTCVAINEAGRA--TGKITLDVGSPPVFIQEPADVSMEI---------GSNVTLPC 814

Query: 135  SVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
             V  G  + T  W +       +   ++ S +Q    A + I ++  SD   Y C AEN 
Sbjct: 815  YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF-ILNLWASDKGTYICEAENQ 872

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
            +G   S   ++TV   V+ P++ +    A       L L C  L G+P P   W  +  +
Sbjct: 873  FGKIQSE-TTVTVTGLVA-PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAM 930

Query: 248  TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLT 306
             L +         S ++   + +  G Y+C A+N  G        +   +PT      + 
Sbjct: 931  LLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL 990

Query: 307  SGVIEGLLSTL 317
            S  IEG+  TL
Sbjct: 991  S-TIEGIPVTL 1000



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 45/180 (25%), Positives = 71/180 (39%), Gaps = 11/180 (6%)

Query: 66   SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
            S   KLQIA     D+G+Y C A  M  K  +     I   +VP +    E  P    V+
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI---QVPPSVAGAEI-PSDVSVL 3259

Query: 126  EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQR----SLTAEYEIPSVRESDAEQY 181
             G+ + L+C+ A G       W K    +    +T+R    +  +   I     SD  +Y
Sbjct: 3260 LGENVELVCN-ANGIPTPLIQWLKDGKPI-ASGETERIRVSANGSTLNIYGALTSDTGKY 3317

Query: 182  YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
             CVA N  G     + ++ V +  +       A +    V+  + + C A    PP + W
Sbjct: 3318 TCVATNPAG-EEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 28/239 (11%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQI      D G Y C A+  A      +   +NVH VP + +  +++     V+  + +
Sbjct: 2928 LQILNTQITDIGRYVCVAENTAGSA--KKYFNLNVH-VPPSVIGPKSE--NLTVVVNNFI 2982

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQ-----RSLTAEYEIPSVRESDAEQYYCVA 185
             L C V+ G       W K    + L + T      R+L    +I   + SD  +Y C+A
Sbjct: 2983 SLTCEVS-GFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL----QIIRAKVSDGGEYTCIA 3037

Query: 186  ENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE-----LHCEALRGSPPILY 240
             N  G S     S+TV +P S    +        +V +V E     L CE+    PP++ 
Sbjct: 3038 INQAGESKKKF-SLTVYVPPS----IKDHDSESLSVVNVREGTSVSLECESNAVPPPVIT 3092

Query: 241  WFYH-EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
            W+ +   IT  +       G   ++   E   +G Y C A N  G +  +   LN  VP
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG-RDDKNFHLNVYVP 3150



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 52/224 (23%), Positives = 84/224 (37%), Gaps = 19/224 (8%)

Query: 80   DTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
            DT +Y C A  +A K  R     +NV        +++  P    ++     VL C +A G
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV------PPNIKGGPQSLVILLNKSTVLEC-IAEG 3738

Query: 140  TGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
                   W K GAV     ++          I S   +D  +Y C+A N  G +    + 
Sbjct: 3739 VPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAG-TDRRRID 3797

Query: 199  ITVRIPVSRPILMLRAPRAQAAVEDV-LELHCEALRGSPPILYWFYHEDITLGSRSAPS- 256
            + V +P S    +   P     + +V   L CEA     P + W  +  +    ++  S 
Sbjct: 3798 LQVHVPPS----IAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSY 3853

Query: 257  ---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
                 G+   +S + + +  Y C   NG G  +   V L   VP
Sbjct: 3854 RLLSSGSLVIISPSVDDTATYECTVTNGAGDDK-RTVDLTVQVP 3896



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 42/155 (27%), Positives = 61/155 (39%), Gaps = 15/155 (9%)

Query: 170  IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
            + S + SD  +Y CVA N  G      + + V +P   P +M         +   +EL C
Sbjct: 2070 LTSAQISDTGRYTCVAVNAAGEKQRD-IDLRVYVP---PNIMGEEQNVSVLISQAVELLC 2125

Query: 230  EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE------EHSGNYSCEANNGLG 283
            ++    PP L W       L       G   S N S+ +      + +G Y+CEA N  G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKK----PGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181

Query: 284  AQRSEAVTLNFTVPTGARSNHLTS-GVIEGLLSTL 317
                      +  P    S+ LT   VIEG L +L
Sbjct: 2182 KTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISL 2216



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 13/231 (5%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
            LQ+     ED+G Y C A   A +V  S+   + V   P  + S E +     V+  + L
Sbjct: 3491 LQLLKAETEDSGKYTCIASNEAGEV--SKHFILKVLEPPHINGSEEHEEI--SVIVNNPL 3546

Query: 131  VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE-YEIPSVRESDAEQYYCVAENGY 189
             L C +A G       W K    L    + Q     E   I + +  D  +Y C+A +  
Sbjct: 3547 ELTC-IASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605

Query: 190  GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVED-VLELHCEALRGSPPILYWFYH-EDI 247
            G          VR+ V   I     PR    + +  + L C++    PP++ W  + E +
Sbjct: 3606 GDDDK---EYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL 3662

Query: 248  TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
                R     GG    ++  +   + NY+C A+N  G    E + L   VP
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFI-LTVNVP 3712



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 37/147 (25%), Positives = 56/147 (38%), Gaps = 19/147 (12%)

Query: 59   RALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
            R LG G      L I     ED G Y C A   A  V RS    + +   P+    +  +
Sbjct: 4397 RQLGNG-----SLAIYGTVNEDAGDYTCVATNEAGVVERSM--SLTLQSPPI----ITLE 4445

Query: 119  PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
            P    +  G +++L C  A G    T  W +    ++   +          I   ++ D 
Sbjct: 4446 PVETVINAGGKIILNCQ-ATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDT 4504

Query: 179  EQYYCVAENGYGPSPSGLVSITVRIPV 205
             ++ CVA N  G       S+ VR+PV
Sbjct: 4505 SEFECVARNLMG-------SVLVRVPV 4524



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 63/257 (24%), Positives = 95/257 (36%), Gaps = 29/257 (11%)

Query: 63   PGWSSSPK---LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
            PG S S     L+I     +DTG Y CEA  +A K    +   +N+   P  ++    + 
Sbjct: 2148 PGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKT--EKNYNVNIWVPP--NIGGSDEL 2203

Query: 120  PGGQVMEGDRLVLICSVAMGTGDITFLW-YKGAVGLNLQSKTQRSLTA--EYEIPSVRES 176
                V+EG+ + L+C  + G      +W  KG+  L       R L+   + +I    +S
Sbjct: 2204 TQLTVIEGNLISLLCE-SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262

Query: 177  DAEQYYCVAENGYGPSPSG-----LVSITVRIPVSRP--ILMLRAPRAQAAVEDVLELHC 229
            DA  Y CVA N  G +         +  T+    S P  I++ R           + L C
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS--------ISLEC 2314

Query: 230  EALRGSPPILYWFY--HEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
            E     PP + W    H  I          G      ++    +G Y C A N  G    
Sbjct: 2315 EVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTD 2373

Query: 288  EAVTLNFTVPTGARSNH 304
            +   L+   P     NH
Sbjct: 2374 KKYDLSVHAPPSIIGNH 2390



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 56/228 (24%), Positives = 82/228 (35%), Gaps = 24/228 (10%)

Query: 71   LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME---- 126
            L I      D G Y C A  +A     +  ++I +H      V  + +PP     +    
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAG----TDETEITLHVQEPPTVE-DLEPPYNTTFQERVA 1280

Query: 127  GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE----YEIPSVRESDAEQYY 182
              R+   C  A GT   T  W     G  L  +       E      I SV   D  +Y 
Sbjct: 1281 NQRIEFPCP-AKGTPKPTIKWLHN--GRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 183  CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAV--EDVLELHCEALRGSPPILY 240
            CVA N  G +     ++ V +P   P++  +      +V    +  L CE      PI+ 
Sbjct: 1338 CVAVNEAGTTERKY-NLKVHVP---PVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIM 1393

Query: 241  WFYHE-DITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQR 286
            W+     +T  S       G    L   T E +G YSC+A N  G  +
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441



 Score = 36.6 bits (83), Expect = 0.045
 Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 19/227 (8%)

Query: 66   SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
            S    L++     ED G Y C  +  A +  +     + V    V + +LE      +V 
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV----KVK 2492

Query: 126  EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYY 182
            E   + L C V  G       W+K   G  LQ      + +     +I +V+     +Y 
Sbjct: 2493 EKQSVTLTCEVT-GNPVPEITWHKD--GQPLQEDEAHHIISGGRFLQITNVQVPHTGRYT 2549

Query: 183  CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE----LHCEALRGSPPI 238
            C+A +  G       S ++ + VS  I  + +      V  +L     L CEA    P  
Sbjct: 2550 CLASSPAGHKSR---SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPAT 2606

Query: 239  LYWFYHEDITLGSRSAP--SGGGASFNLSLTEEHSGNYSCEANNGLG 283
            + WF        +R+     GG     L+  E+++G YSC A N  G
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 51/219 (23%), Positives = 86/219 (39%), Gaps = 14/219 (6%)

Query: 70   KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
            KL+I +  + D G Y C A ++A +  +  + +++V   P  +   ET      VM  + 
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGE--KEIKYEVDVLVPPAIEGGDETS--YFIVMVNNL 1751

Query: 130  LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENG 188
            L L C V  G+   T +W K    ++ +   +  L   +  I   + S+   Y C+A N 
Sbjct: 1752 LELDCHVT-GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANT 1810

Query: 189  YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWFYHE-- 245
             G        +TV +P   P +       +  V+   + L C A     P + W   +  
Sbjct: 1811 AGDHKKEF-EVTVHVP---PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866

Query: 246  -DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
             +   G+    S G          E +G Y+C A N  G
Sbjct: 1867 VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAG 1905


>gi|157819143 IgLON family member 5 [Homo sapiens]
          Length = 336

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 67/273 (24%), Positives = 110/273 (40%), Gaps = 40/273 (14%)

Query: 65  WSSSPKLQIAAMWKE------------DTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD 112
           W+S P++++     E            D G Y C  QT       + +  + VH VP   
Sbjct: 79  WTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPY--TTQVYLIVH-VPARI 135

Query: 113 VSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPS 172
           V++ +      V EG  + L+C +A+G  + T  W +   G   + +         EI  
Sbjct: 136 VNISSPVT---VNEGGNVNLLC-LAVGRPEPTVTWRQLRDGFTSEGEI-------LEISD 184

Query: 173 VRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
           ++   A +Y CV  NG   +P    S  V + V+ P  +     A+ A+     L CEA+
Sbjct: 185 IQRGQAGEYECVTHNGVNSAPD---SRRVLVTVNYPPTITDVTSARTALGRAALLRCEAM 241

Query: 233 RGSPPILYWFYHEDITLGSRSAPS-------GGGASFNLSLTEEHSGNYSCEANNGLGAQ 285
              PP  + +Y +D  L S +A                 +++  H GNY+C A N LGA 
Sbjct: 242 -AVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGA- 299

Query: 286 RSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLG 318
              + ++    P    ++      +  LLS LG
Sbjct: 300 --SSASMRLLRPGSLENSAPRPPGLLALLSALG 330



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 48/191 (25%), Positives = 71/191 (37%), Gaps = 28/191 (14%)

Query: 16  PAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-LQIA 74
           PA +  I+SP    EG  V L C           +        R L  G++S  + L+I+
Sbjct: 132 PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW--------RQLRDGFTSEGEILEIS 183

Query: 75  AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLI 133
            + +   G Y C      +    SRR  + V+  P + DV+      G       R  L+
Sbjct: 184 DIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALG-------RAALL 236

Query: 134 CSVAMGTGDITFLWYKG--------AVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
              AM      F WYK         A GL +Q++  RS+       +V       Y C A
Sbjct: 237 RCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLL---FANVSARHYGNYTCRA 293

Query: 186 ENGYGPSPSGL 196
            N  G S + +
Sbjct: 294 ANRLGASSASM 304


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 76/324 (23%), Positives = 123/324 (37%), Gaps = 32/324 (9%)

Query: 68  SPKLQIA---------AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
           SP+LQ++         ++ + DTG Y CE Q   S    + RS      V     +    
Sbjct: 188 SPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVS----ANRSDPVTLNVTYGPDTPTIS 243

Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
           P       G  L L C  A       + W        L + T +  T E  IP++  +++
Sbjct: 244 PSDTYYRPGANLSLSCYAASNP-PAQYSW--------LINGTFQQSTQELFIPNITVNNS 294

Query: 179 EQYYCVAEN---GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGS 235
             Y C A N   G   +    + +T   PV     +  +       +D + L C      
Sbjct: 295 GSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTG 354

Query: 236 PPILYWFYHEDITLGSRSAPSGGGASFNLS-LTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
             I ++F ++ +    R   S G  + +++ +  E +G Y CE  N +   +S+ + LN 
Sbjct: 355 ISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNV 414

Query: 295 TVPTGARSNHLTSGVIEGLLSTLGPATVAL----LFCYGLKRKIGRRS-ARDPLRSLPSP 349
                 + N L+ G I G++  +  A VAL    L C+    K GR S  RD     PS 
Sbjct: 415 NYNALPQENGLSPGAIAGIVIGV-VALVALIAVALACFLHFGKTGRASDQRDLTEHKPSV 473

Query: 350 LPQEFTYLNSPTPGQLQPIYENVN 373
                 + N P     +  Y  +N
Sbjct: 474 SNHTQDHSNDPPNKMNEVTYSTLN 497



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 1/75 (1%)

Query: 222 EDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANN 280
           +D +   CE        L+W  ++ + +  R   S G  +  L S+T   +G Y CE  N
Sbjct: 160 KDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQN 219

Query: 281 GLGAQRSEAVTLNFT 295
            + A RS+ VTLN T
Sbjct: 220 PVSANRSDPVTLNVT 234


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,898,909
Number of Sequences: 37866
Number of extensions: 873956
Number of successful extensions: 3866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 2569
Number of HSP's gapped (non-prelim): 1082
length of query: 429
length of database: 18,247,518
effective HSP length: 105
effective length of query: 324
effective length of database: 14,271,588
effective search space: 4623994512
effective search space used: 4623994512
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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