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Search of human proteins with 163914371
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163914371 solute carrier family 8 (sodium/calcium
exchanger), member 1 isoform C [Homo sapiens]
(960 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163914371 solute carrier family 8 (sodium/calcium exchanger),... 1917 0.0
gi|163914369 solute carrier family 8 (sodium/calcium exchanger),... 1868 0.0
gi|10863913 solute carrier family 8 (sodium/calcium exchanger), ... 1862 0.0
gi|163914373 solute carrier family 8 (sodium/calcium exchanger),... 1859 0.0
gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ... 1317 0.0
gi|33946304 solute carrier family 8 (sodium/calcium exchanger), ... 1315 0.0
gi|17865805 solute carrier family 8 (sodium/calcium exchanger), ... 1314 0.0
gi|15147254 solute carrier family 8 (sodium/calcium exchanger), ... 1296 0.0
gi|57163987 solute carrier family 8 member 2 [Homo sapiens] 1207 0.0
gi|194354001 solute carrier family 8 (sodium/calcium exchanger),... 475 e-134
gi|33946308 solute carrier family 8 (sodium/calcium exchanger), ... 471 e-132
gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens] 84 5e-16
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 72 2e-12
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 72 2e-12
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 72 2e-12
gi|108773804 Fraser syndrome 1 [Homo sapiens] 69 2e-11
gi|79749430 FRAS1-related extracellular matrix protein 2 precurs... 69 3e-11
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e... 68 4e-11
gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sa... 65 2e-10
gi|29788985 solute carrier family 24 member 4 isoform 2 precurso... 65 2e-10
gi|24111228 solute carrier family 24 member 4 isoform 1 precurso... 65 2e-10
gi|45504369 solute carrier family 24, member 5 [Homo sapiens] 64 9e-10
gi|9966787 solute carrier family 24 (sodium/potassium/calcium ex... 59 3e-08
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 51 6e-06
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 51 6e-06
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 51 6e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 51 6e-06
gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens] 45 3e-04
gi|39995086 solute carrier family 24 member 6 [Homo sapiens] 37 0.12
gi|209862785 anoctamin 2 [Homo sapiens] 36 0.15
>gi|163914371 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform C [Homo sapiens]
Length = 960
Score = 1917 bits (4966), Expect = 0.0
Identities = 960/960 (100%), Positives = 960/960 (100%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHAREHPILS 660
EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHAREHPILS
Sbjct: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHAREHPILS 660
Query: 661 TVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKT 720
TVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKT
Sbjct: 661 TVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKT 720
Query: 721 NLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVP 780
NLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVP
Sbjct: 721 NLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVP 780
Query: 781 PTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFAS 840
PTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFAS
Sbjct: 781 PTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFAS 840
Query: 841 KVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900
KVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL
Sbjct: 841 KVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900
Query: 901 FTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 960
FTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF
Sbjct: 901 FTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 960
>gi|163914369 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform B [Homo sapiens]
Length = 968
Score = 1868 bits (4838), Expect = 0.0
Identities = 939/968 (97%), Positives = 947/968 (97%), Gaps = 8/968 (0%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMK--------GGFTITGQPVFRKVH 652
EIVK I++++ D EEYEK +F L + EP+ + K GGFTITGQPVFRKVH
Sbjct: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGQPVFRKVH 660
Query: 653 AREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKST 712
AREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKST
Sbjct: 661 AREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKST 720
Query: 713 VDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFW 772
VDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFW
Sbjct: 721 VDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFW 780
Query: 773 KVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGT 832
KVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGT
Sbjct: 781 KVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGT 840
Query: 833 SVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPG 892
SVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPG
Sbjct: 841 SVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPG 900
Query: 893 TLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLE 952
TLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLE
Sbjct: 901 TLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLE 960
Query: 953 AYCHIKGF 960
AYCHIKGF
Sbjct: 961 AYCHIKGF 968
>gi|10863913 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform A [Homo sapiens]
Length = 973
Score = 1862 bits (4822), Expect = 0.0
Identities = 939/973 (96%), Positives = 947/973 (97%), Gaps = 13/973 (1%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMK--------GGFTIT-----GQPV 647
EIVK I++++ D EEYEK +F L + EP+ + K GGFTIT GQPV
Sbjct: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
Query: 648 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 707
FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY
Sbjct: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 720
Query: 708 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 767
EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF
Sbjct: 721 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 780
Query: 768 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 827
LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF
Sbjct: 781 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 840
Query: 828 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 887
VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF
Sbjct: 841 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 900
Query: 888 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 947
KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF
Sbjct: 901 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 960
Query: 948 FSSLEAYCHIKGF 960
FSSLEAYCHIKGF
Sbjct: 961 FSSLEAYCHIKGF 973
>gi|163914373 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform D [Homo sapiens]
Length = 937
Score = 1859 bits (4815), Expect = 0.0
Identities = 937/960 (97%), Positives = 937/960 (97%), Gaps = 23/960 (2%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHAREHPILS 660
EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTIT
Sbjct: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTIT----------------- 643
Query: 661 TVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKT 720
DEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKT
Sbjct: 644 ------DEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKT 697
Query: 721 NLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVP 780
NLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVP
Sbjct: 698 NLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVP 757
Query: 781 PTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFAS 840
PTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFAS
Sbjct: 758 PTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFAS 817
Query: 841 KVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900
KVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL
Sbjct: 818 KVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 877
Query: 901 FTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 960
FTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF
Sbjct: 878 FTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 937
>gi|33946311 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform C precursor [Homo sapiens]
Length = 927
Score = 1317 bits (3409), Expect = 0.0
Identities = 674/965 (69%), Positives = 785/965 (81%), Gaps = 46/965 (4%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVST---LACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHARE 655
EF+NDE VK I ++I D EEYE++ +F + L EPKW+ RG
Sbjct: 588 EFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERG-------------------- 627
Query: 656 HPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDK 715
+S ++ D D K LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDK
Sbjct: 628 ---ISALLLSPDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDK 682
Query: 716 LIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVL 775
LIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVL
Sbjct: 683 LIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVL 742
Query: 776 FAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVP 835
FA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVP
Sbjct: 743 FACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVP 802
Query: 836 DTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLA 895
DTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLA
Sbjct: 803 DTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLA 862
Query: 896 FSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYC 955
FSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LWLLYI F++LEAYC
Sbjct: 863 FSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYC 922
Query: 956 HIKGF 960
+IKGF
Sbjct: 923 YIKGF 927
>gi|33946304 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform D precursor [Homo sapiens]
Length = 921
Score = 1315 bits (3403), Expect = 0.0
Identities = 674/965 (69%), Positives = 783/965 (81%), Gaps = 52/965 (5%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVST---LACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHARE 655
EF+NDE VK I ++I D EEYE++ +F + L EPKW+ RG
Sbjct: 588 EFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERG-------------------- 627
Query: 656 HPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDK 715
I+D D K LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDK
Sbjct: 628 ---------ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDK 676
Query: 716 LIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVL 775
LIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVL
Sbjct: 677 LIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVL 736
Query: 776 FAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVP 835
FA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVP
Sbjct: 737 FACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVP 796
Query: 836 DTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLA 895
DTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLA
Sbjct: 797 DTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLA 856
Query: 896 FSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYC 955
FSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LWLLYI F++LEAYC
Sbjct: 857 FSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYC 916
Query: 956 HIKGF 960
+IKGF
Sbjct: 917 YIKGF 921
>gi|17865805 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform B precursor [Homo sapiens]
Length = 924
Score = 1314 bits (3401), Expect = 0.0
Identities = 672/965 (69%), Positives = 784/965 (81%), Gaps = 49/965 (5%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVST---LACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHARE 655
EF+NDE VK I ++I D EEYE++ +F + L EPKW+ RG
Sbjct: 588 EFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERG-------------------- 627
Query: 656 HPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDK 715
+S ++ D + LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDK
Sbjct: 628 ---ISALLLSPD-----RKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDK 679
Query: 716 LIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVL 775
LIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVL
Sbjct: 680 LIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVL 739
Query: 776 FAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVP 835
FA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVP
Sbjct: 740 FACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVP 799
Query: 836 DTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLA 895
DTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLA
Sbjct: 800 DTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLA 859
Query: 896 FSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYC 955
FSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LWLLYI F++LEAYC
Sbjct: 860 FSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYC 919
Query: 956 HIKGF 960
+IKGF
Sbjct: 920 YIKGF 924
>gi|15147254 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform A precursor [Homo sapiens]
Length = 925
Score = 1296 bits (3354), Expect = 0.0
Identities = 663/965 (68%), Positives = 776/965 (80%), Gaps = 48/965 (4%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS---TLACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITGQPVFRKVHARE 655
EF+NDE VK I I++ D E YEK ++ + + P+ + + ++
Sbjct: 588 EFKNDETVKTIHIKVIDDEAYEKNKNYFIEMMGPRMVDMSFQKALLLS------------ 635
Query: 656 HPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDK 715
+ LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDK
Sbjct: 636 ---------------PDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDK 680
Query: 716 LIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVL 775
LIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVL
Sbjct: 681 LIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVL 740
Query: 776 FAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVP 835
FA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVP
Sbjct: 741 FACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVP 800
Query: 836 DTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLA 895
DTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLA
Sbjct: 801 DTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLA 860
Query: 896 FSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYC 955
FSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LWLLYI F++LEAYC
Sbjct: 861 FSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYC 920
Query: 956 HIKGF 960
+IKGF
Sbjct: 921 YIKGF 925
>gi|57163987 solute carrier family 8 member 2 [Homo sapiens]
Length = 921
Score = 1207 bits (3123), Expect = 0.0
Identities = 605/917 (65%), Positives = 731/917 (79%), Gaps = 37/917 (4%)
Query: 46 TGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEV 105
TG C GSY C+ GV+LP+WEP DPS GDK ARA VYFVAMVYMFLGVSIIADRFM++IEV
Sbjct: 40 TGGCQGSYRCQPGVLLPVWEPDDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMAAIEV 99
Query: 106 ITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGD 165
ITS+EKEITI K NGET+ TVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNF AG+
Sbjct: 100 ITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGE 159
Query: 166 LGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVI 225
LGP TIVGSAAFNMF++IA+C+YV+P GE+RKIKHLRVFFVTA+WSIFAY WLY+IL+V
Sbjct: 160 LGPGTIVGSAAFNMFVVIAVCIYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVF 219
Query: 226 SPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSS 285
SPGVV+VWE LLT FFP+CVVFAW+AD+RLLFYKYVYKRYR + G+II EGD P S
Sbjct: 220 SPGVVQVWEALLTLVFFPVCVVFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKS 279
Query: 286 KTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQL 345
IE+DG V + L G + R+ D +RRE+ +ILK+LKQKHPDK++EQL
Sbjct: 280 ---IELDGTFVGAEAPGELGGLGPGPAEARELD--ASRREVIQILKDLKQKHPDKDLEQL 334
Query: 346 IELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDP 405
+ +ANY L QQKSRAFYRIQATRLMTGAGN+L+RHAAD +R+A + E+D
Sbjct: 335 VGIANYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADASRRAAPAEGAGED--EDDG 392
Query: 406 VSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVV 465
S+IFFE Y CLENCG+V L++ +GG+ +T +VD+RTEDG+A AGSDYE++EGT+V
Sbjct: 393 ASRIFFEPSLYHCLENCGSVLLSVTCQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLV 452
Query: 466 FKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS-TLACLGSP 524
FKPG+TQKE+R+GIIDDDIFEEDE+F V L N++V G+ E + L +P
Sbjct: 453 FKPGETQKELRIGIIDDDIFEEDEHFFVRLLNLRV---GDAQGMFEPDGGGRPKGRLVAP 509
Query: 525 STATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG 584
ATVTI DDDHAGIF+F++ + HVSE +G ++V+V+R+SGARG V +PY+T++GTARGG
Sbjct: 510 LLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGG 569
Query: 585 GEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITG 644
G +ED CGELEF +DE +K + ++I D EEYEK+ +F + L +P+W++RG+
Sbjct: 570 GVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKRGISA------ 623
Query: 645 QPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIE 704
+ ++ D + LT++EEE RRIAEMG+P+LGE+ +LEVIIE
Sbjct: 624 -------------------LLLNQGDGDRKLTAEEEEARRIAEMGKPVLGENCRLEVIIE 664
Query: 705 ESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAG-EDDDDDECGEEKLPSCFDY 763
ESY+FK+TVDKLIKKTNLALV+GT+SWREQF+EAITVSAG E++++D EE+LPSCFDY
Sbjct: 665 ESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITVSAGDEEEEEDGSREERLPSCFDY 724
Query: 764 VMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVT 823
VMHFLTVFWKVLFA VPPTEY +GWACF VSIL+IGLLTA IGDLASHFGCT+GLKDSV
Sbjct: 725 VMHFLTVFWKVLFACVPPTEYCHGWACFGVSILVIGLLTALIGDLASHFGCTVGLKDSVN 784
Query: 824 AVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAAN 883
AVVFVALGTS+PDTFASKVAA QDQ ADASIGNVTGSNAVNVFLG+GVAWS+AA+Y A
Sbjct: 785 AVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQ 844
Query: 884 GEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWL 943
G F+V GTLAFSVTLFT+FAF+ + VLLYRRRP IGGELGGPR KL T+ LF+ LWL
Sbjct: 845 GRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFLGLWL 904
Query: 944 LYIFFSSLEAYCHIKGF 960
LYI F+SLEAYCHI+GF
Sbjct: 905 LYILFASLEAYCHIRGF 921
>gi|194354001 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform G [Homo sapiens]
Length = 298
Score = 475 bits (1223), Expect = e-134
Identities = 237/296 (80%), Positives = 263/296 (88%), Gaps = 2/296 (0%)
Query: 665 IADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLAL 724
I+D D K LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLAL
Sbjct: 5 ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLAL 62
Query: 725 VVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEY 784
VVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY
Sbjct: 63 VVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEY 122
Query: 785 WNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAA 844
+GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA
Sbjct: 123 CHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAA 182
Query: 845 TQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF 904
QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLAFSVTLFTIF
Sbjct: 183 LQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIF 242
Query: 905 AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 960
AF+ + VLLYRRRP +GGELGGPR KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 243 AFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
>gi|33946308 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform F [Homo sapiens]
Length = 284
Score = 471 bits (1212), Expect = e-132
Identities = 231/283 (81%), Positives = 256/283 (90%)
Query: 678 KEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIE 737
+EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLALVVGT+SWR+QF+E
Sbjct: 2 EEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFME 61
Query: 738 AITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILM 797
AITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+
Sbjct: 62 AITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILI 121
Query: 798 IGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNV 857
IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA QD YADASIGNV
Sbjct: 122 IGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNV 181
Query: 858 TGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRR 917
TGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLAFSVTLFTIFAF+ + VLLYRRR
Sbjct: 182 TGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRR 241
Query: 918 PEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 960
P +GGELGGPR KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 242 PHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 284
>gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]
Length = 6306
Score = 84.3 bits (207), Expect = 5e-16
Identities = 66/233 (28%), Positives = 110/233 (47%), Gaps = 6/233 (2%)
Query: 398 TEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDY 457
T V + P + F + E V +TIIR GD + V + ++T GTA AG D+
Sbjct: 4258 TVVASDSPYGRFAFSHEQLRVSE-AQRVNITIIRSSGDFGH-VRLWYKTMSGTAEAGLDF 4315
Query: 458 EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEAN-HVS 516
G ++F+ G+ +K + V I+DDD E E F + ++ V++ + I E +
Sbjct: 4316 VPAAGELLFEAGEMRKSLHVEILDDDYPEGPEEFSLTITKVELQGRGYDFTIQENGLQID 4375
Query: 517 TLACLGSPSTATVTIFDDDHA-GIFTFEEPVT--HVSESIGIMEVKVLRTSGARGNVIVP 573
+G+ S + I +D+A GI F+ T V E +G++ + V+R G G V
Sbjct: 4376 QPPEIGNISIVRIIIMKNDNAEGIIEFDPKYTAFEVEEDVGLIMIPVVRLHGTYGYVTAD 4435
Query: 574 YKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
+ + +A GG D+ + FQ+ + + I I I D E E E ++L
Sbjct: 4436 FISQSSSASPGGVDYILHGSTVTFQHGQNLSFINISIIDDNESEFEEPIEILL 4488
Score = 72.0 bits (175), Expect = 2e-12
Identities = 67/221 (30%), Positives = 100/221 (45%), Gaps = 21/221 (9%)
Query: 420 ENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGI 479
E G + L +IR G L V +FRT TA + DY+ GT+ F+PG+ K I + I
Sbjct: 1734 EEDGEIRLLVIRAQG-LLGRVTAEFRTVSLTAFSPEDYQNVAGTLEFQPGERYKYIFINI 1792
Query: 480 IDDDIFEEDENFLVHLSNV--------KVSSEASEDGILE--ANHVSTLACLGSPSTATV 529
D+ I E +++F V L N+ +V S DG +E + A LG S V
Sbjct: 1793 TDNSIPELEKSFKVELLNLEGGVAELFRVDGSGSGDGDMEFFLPTIHKRASLGVASQILV 1852
Query: 530 TIFDDDHA-GIFTFEEPVTHVS-----ESIGIMEVKVLRTSGARGNVIVPYKTIEGTARG 583
TI DHA G+F F VS + + + V+R G V + + I+ G
Sbjct: 1853 TIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVTLNVIRHHGTLSPVTLHW-NIDSDPDG 1911
Query: 584 GGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSL 624
D T G + F+ + IT+ I E+ E + +FS+
Sbjct: 1912 ---DLAFTSGNITFEIGQTSANITVEILPDEDPELDKAFSV 1949
Score = 68.6 bits (166), Expect = 3e-11
Identities = 65/224 (29%), Positives = 93/224 (41%), Gaps = 27/224 (12%)
Query: 410 FFEQGTYQCLENCGTVALTIIRRGGDLTN-TVFVDFRTEDGTANAGSDYEFTEGTVVFKP 468
F Q + E TV II R G+ N T V ED D+ T
Sbjct: 35 FTGQTEFVVNETSTTVIRLIIERIGEPANVTAIVSLYGEDA-----GDFFDTYAAAFIPA 89
Query: 469 GDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTAT 528
G+T + + + + DDD+ E DE F+ HL+ K S+ LG P T T
Sbjct: 90 GETNRTVYIAVCDDDLPEPDETFIFHLTLQKPSANVK---------------LGWPRTVT 134
Query: 529 VTIFDDDHA-GIFTFEE-PVTHVSESIG---IMEVKVLRTSGARGNVIVPYKTIEGTARG 583
VTI +D+A GI +F P VSE G M + ++R G G V+V ++ +EG
Sbjct: 135 VTILSNDNAFGIISFNMLPSIAVSEPKGRNESMPLTLIREKGTYGMVMVTFE-VEGGPNP 193
Query: 584 GGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLE 627
ED G + F I + + D E E + F + L+
Sbjct: 194 PDEDLSPVKGNITFPPGRATVIYNLTVLDDEVPENDEIFLIQLK 237
Score = 66.2 bits (160), Expect = 1e-10
Identities = 66/230 (28%), Positives = 101/230 (43%), Gaps = 40/230 (17%)
Query: 420 ENCGTVALTIIRRGGDLTNTVFVDFRTE-------DGTANAGSDYEFTEGTVVFKPGDTQ 472
EN T+ L I R G L + + R + D A DY E ++ K +
Sbjct: 3793 ENTTTLQLQIARDKG-LLGDIAIHLRAQPNFLLHVDNQATENEDYVLQETIIIMKENIKE 3851
Query: 473 KEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPST------ 526
V I+ DD+ E +E F+V I E N V++ G PS
Sbjct: 3852 AHAEVSILPDDLPELEEGFIV--------------TITEVNLVNSDFSTGQPSVRRPGME 3897
Query: 527 -ATVTIFD-DDHAGIFTFE------EPVT--HVSESIGIMEVKVLRTSGARGNVIVPYKT 576
A + I + DD GIF F E +T V + +++V V+R +G+ G V V +K
Sbjct: 3898 IAEIMIEENDDPRGIFMFHVTRGAGEVITAYEVPPPLNVLQVPVVRLAGSFGAVNVYWKA 3957
Query: 577 IEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
+A G EDF+ + G LEF + ++ +I I I D E+E +F++ L
Sbjct: 3958 SPDSA--GLEDFKPSHGILEFADKQVTAMIEITIIDDAEFELTETFNISL 4005
Score = 64.3 bits (155), Expect = 5e-10
Identities = 63/228 (27%), Positives = 92/228 (40%), Gaps = 27/228 (11%)
Query: 420 ENCGTVALTIIRRGG--DLTNTVFVDFRTE-DGTANAGSDYEFTEGTVVFKPGDTQKEIR 476
E T++ + R G D + + + E DG D+ GT+ F P + +
Sbjct: 1587 EEGSTISCVVERTRGALDYVHVFYTISQIETDGINYLVDDFANASGTITFLPWQRSEVLN 1646
Query: 477 VGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDH 536
+ ++DDDI E +E F V + S DG L + S + T +TI DH
Sbjct: 1647 IYVLDDDIPELNEYF-----RVTLVSAIPGDGKLGSTPTSGASIDPEKETTDITIKASDH 1701
Query: 537 A-GIFTFEE-----------------PVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIE 578
G+ F P V E G + + V+R G G V ++T+
Sbjct: 1702 PYGLLQFSTGLPPQPKDAMTLPASSVPHITVEEEDGEIRLLVIRAQGLLGRVTAEFRTVS 1761
Query: 579 GTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
TA ED+++ G LEFQ E K I I I D E E SF + L
Sbjct: 1762 LTA-FSPEDYQNVAGTLEFQPGERYKYIFINITDNSIPELEKSFKVEL 1808
Score = 62.8 bits (151), Expect = 2e-09
Identities = 61/199 (30%), Positives = 85/199 (42%), Gaps = 33/199 (16%)
Query: 449 GTANAGSDYE-FTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFL-----VHLSNVKVSS 502
G A AGSDYE T + + GD + V I+ DD E DE+FL VHL N+ S
Sbjct: 2495 GQAVAGSDYEPVTRQWAIMQEGDEFANLTVSILPDDFPEMDESFLISLLEVHLMNISAS- 2553
Query: 503 EASEDGILEANHVSTLACLGSPSTATVTI-FDDDHAGIFTFEEPVTHVSES--------- 552
+ +G P+ +TV I + D G+F + SE
Sbjct: 2554 ------------LKNQPTIGQPNISTVVIALNGDAFGVFVIYNISPNTSEDGLFVEVQEQ 2601
Query: 553 -IGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIF 611
++E+ + RT G+ G V V ++ + GTA G DF L F E K + + I
Sbjct: 2602 PQTLVELMIHRTGGSLGQVAVEWRVVGGTAT-EGLDFIGAGEILTFAEGETKKTVILTIL 2660
Query: 612 DREEYEKECSF--SLVLEE 628
D E E + S SLV E
Sbjct: 2661 DDSEPEDDESIIVSLVYTE 2679
Score = 62.0 bits (149), Expect = 3e-09
Identities = 60/214 (28%), Positives = 98/214 (45%), Gaps = 23/214 (10%)
Query: 423 GTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDD 482
GT ++++R G + V V +R + ++ T G + + + + + ++D
Sbjct: 4171 GTAIISLVR-GPGILGEVTVFWRIFPPSVG---EFAETSGKLTMRDEQSAVIVVIQALND 4226
Query: 483 DIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHA-GIFT 541
DI EE + L+ V SE G+L S STA +T+ D G F
Sbjct: 4227 DIPEEKSFYEFQLTAV------SEGGVLSE----------SSSTANITVVASDSPYGRFA 4270
Query: 542 FEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDE 601
F VSE+ + + ++R+SG G+V + YKT+ GTA G DF GEL F+ E
Sbjct: 4271 FSHEQLRVSEAQRV-NITIIRSSGDFGHVRLWYKTMSGTAEAG-LDFVPAAGELLFEAGE 4328
Query: 602 IVKIITIRIFDREEYEKECSFSLVLEEPKWIRRG 635
+ K + + I D + E FSL + + + RG
Sbjct: 4329 MRKSLHVEILDDDYPEGPEEFSLTITKVELQGRG 4362
Score = 60.8 bits (146), Expect = 6e-09
Identities = 58/204 (28%), Positives = 92/204 (45%), Gaps = 22/204 (10%)
Query: 425 VALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDI 484
V L I R GG L V V++R GTA G D+ + F G+T+K + + I+DD
Sbjct: 2606 VELMIHRTGGSL-GQVAVEWRVVGGTATEGLDFIGAGEILTFAEGETKKTVILTILDDSE 2664
Query: 485 FEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDH-AGIFTFE 543
E+DE+ +V L + S L S T V I +D+ AGI +F+
Sbjct: 2665 PEDDESIIVSLVYTEGGSR----------------ILPSSDTVRVNILANDNVAGIVSFQ 2708
Query: 544 EPVTHVSESIG-IMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEI 602
V G I++ V+RT RGNV V +K I + +F + G+L F +
Sbjct: 2709 TASRSVIGHEGEILQFHVIRTFPGRGNVTVNWKII---GQNLELNFANFSGQLFFPEGSL 2765
Query: 603 VKIITIRIFDREEYEKECSFSLVL 626
+ + + D E++ + ++L
Sbjct: 2766 NTTLFVHLLDDNIPEEKEVYQVIL 2789
Score = 60.5 bits (145), Expect = 7e-09
Identities = 65/247 (26%), Positives = 98/247 (39%), Gaps = 27/247 (10%)
Query: 398 TEVTENDPVSKIFFEQGT--YQCLENCGTVALTIIRRGGDLTNTVFVDFRTED------- 448
T + +DP F + + E + L+IIR G L V V + T D
Sbjct: 1968 TVLASDDPYGIFIFSEKNRPVKVEEATQNITLSIIRLKG-LMGKVLVSYATLDDMEKPPY 2026
Query: 449 -----GTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSN----VK 499
A G DY G +F ++ I + I+DDD E E+ + L N K
Sbjct: 2027 FPPNLARATQGRDYIPASGFALFGANQSEATIAISILDDDEPERSESVFIELLNSTLVAK 2086
Query: 500 VSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVK 559
V S + + V T+A L + I +DD G P+ V+E+ +
Sbjct: 2087 VQSRSIPNSPRLGPKVETIAQL-------IIIANDDAFGTLQLSAPIVRVAENHVGPIIN 2139
Query: 560 VLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKE 619
V RT GA +V V +K + TA GED+ ++ E K + I + + E E
Sbjct: 2140 VTRTGGAFADVSVKFKAVPITAI-AGEDYSIASSDVVLLEGETSKAVPIYVINDIYPELE 2198
Query: 620 CSFSLVL 626
SF + L
Sbjct: 2199 ESFLVQL 2205
Score = 57.4 bits (137), Expect = 6e-08
Identities = 60/218 (27%), Positives = 92/218 (42%), Gaps = 38/218 (17%)
Query: 424 TVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDD 483
TV L +IR G L+ V + + + ++ D FT G + F+ G T I V I+ D+
Sbjct: 1884 TVTLNVIRHHGTLS-PVTLHWNID---SDPDGDLAFTSGNITFEIGQTSANITVEILPDE 1939
Query: 484 IFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIF-DDDHAGIFTF 542
E D+ F V + +V S LG+ AT+T+ DD GIF F
Sbjct: 1940 DPELDKAFSVSVLSVSSGS------------------LGAHINATLTVLASDDPYGIFIF 1981
Query: 543 EE---PVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTAR-----------GGGEDF 588
E PV V E+ + + ++R G G V+V Y T++ + G D+
Sbjct: 1982 SEKNRPV-KVEEATQNITLSIIRLKGLMGKVLVSYATLDDMEKPPYFPPNLARATQGRDY 2040
Query: 589 EDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
G F ++ I I I D +E E+ S + L
Sbjct: 2041 IPASGFALFGANQSEATIAISILDDDEPERSESVFIEL 2078
Score = 57.4 bits (137), Expect = 6e-08
Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 26/190 (13%)
Query: 427 LTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFE 486
+ + R GG + V V F+ TA AG DY VV G+T K + + +I+D E
Sbjct: 2138 INVTRTGGAFAD-VSVKFKAVPITAIAGEDYSIASSDVVLLEGETSKAVPIYVINDIYPE 2196
Query: 487 EDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTI-FDDDHAGIFTFEEP 545
+E+FLV L N A LG+ + A + I DD G+F F+
Sbjct: 2197 LEESFLVQLMNETTGG----------------ARLGALTEAVIIIEASDDPYGLFGFQIT 2240
Query: 546 VTHVSE----SIGIMEVKVLRTSGARGNVIVPY-KTIEGTARGGGEDFEDTCGELEFQND 600
V E S+ + + ++R SG GNV V + TI G G D G + F
Sbjct: 2241 KLIVEEPEFNSVKV-NLPIIRNSGTLGNVTVQWVATINGQLATG--DLRVVSGNVTFAPG 2297
Query: 601 EIVKIITIRI 610
E ++ + + +
Sbjct: 2298 ETIQTLLLEV 2307
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/194 (28%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 423 GTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS-DYEFTE--GTVVFKPGDTQKEIRVGI 479
G A + R G + T V + T+DG A A D+ E T++F+ G Q+ I + +
Sbjct: 1017 GETANFTVLRNGSVDVTCMVQYATKDGKATARERDFIPVEKGETLIFEVGSRQQSISIFV 1076
Query: 480 IDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTI-FDDDHAG 538
+D I E DE F + L N + + G+ ATV I +DD G
Sbjct: 1077 NEDGIPETDEPFYIILLNSTGDTVVYQYGV-----------------ATVIIEANDDPNG 1119
Query: 539 IFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEG-TARGGGEDFEDTCGELEF 597
IF+ EP+ E +LR G G+V V ++ + +A G++F +T G + F
Sbjct: 1120 IFSL-EPIDKAVEEGKTNAFWILRHRGYFGSVSVSWQLFQNDSALQPGQEFYETSGTVNF 1178
Query: 598 QNDEIVKIITIRIF 611
+ E K I + F
Sbjct: 1179 MDGEEAKPIILHAF 1192
Score = 56.2 bits (134), Expect = 1e-07
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 27/161 (16%)
Query: 455 SDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANH 514
SD+ + G ++F+PG+ + I V I+DD + E++E+F V L N K +E
Sbjct: 3585 SDFIPSSGELIFEPGEREATIAVNILDDTVPEKEESFKVQLKNPKGGAE----------- 3633
Query: 515 VSTLACLGSPSTATVTIFDDDHA-GIFTFEEPVTHVS----ESIGIMEVKVLRTSGARGN 569
+G + T+TI +D A GI F + + E ++ + V R G G
Sbjct: 3634 ------IGINDSVTITILSNDDAYGIVAFAQNSLYKQVEEMEQDSLVTLNVERLKGTYGR 3687
Query: 570 VIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRI 610
+ TI A G D T G + F +++ IT+ I
Sbjct: 3688 I-----TIAWEADGSISDIFPTSGVILFTEGQVLSTITLTI 3723
Score = 54.3 bits (129), Expect = 5e-07
Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 8/221 (3%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKP 468
I ++Q ++ E G++ L + +R + V + ++ A G DY FT + F
Sbjct: 2962 IEWQQSRFEVNETHGSLTL-VAQRSREPLGHVSLFVYAQNLEAQVGLDYIFTPMILHFAD 3020
Query: 469 GDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTAT 528
G+ K + + I+DDDI E DE F + L+N E L N ++ + L +
Sbjct: 3021 GERYKNVNIMILDDDIPEGDEKFQLILTNPSPGLE------LGKNTIALIIVLANDDGPG 3074
Query: 529 VTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDF 588
V F++ F E +V ES+ ++ + G G V V + E + +D
Sbjct: 3075 VLSFNNSE-HFFLREPTALYVQESVAVLYIVREPAQGLFGTVTVQFIVTEVNSSNESKDL 3133
Query: 589 EDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLEEP 629
+ G + + K + I E E + F L P
Sbjct: 3134 TPSKGYIVLEEGVRFKALQISAILDTEPEMDEYFVCTLFNP 3174
Score = 46.6 bits (109), Expect = 1e-04
Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 12/170 (7%)
Query: 462 GTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACL 521
G ++ + G+T I + I++DD+ E +E FLV+L+ V G+ A S L
Sbjct: 2891 GFLILEEGETAAAINITILEDDVPELEEYFLVNLTYV---------GLTMAASTSFPPRL 2941
Query: 522 GSPSTATVTIFD--DDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEG 579
S I D D G+ +++ V+E+ G + + R+ G+V + + +
Sbjct: 2942 DSEGLTAQVIIDANDGARGVIEWQQSRFEVNETHGSLTLVAQRSREPLGHVSL-FVYAQN 3000
Query: 580 TARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLEEP 629
G D+ T L F + E K + I I D + E + F L+L P
Sbjct: 3001 LEAQVGLDYIFTPMILHFADGERYKNVNIMILDDDIPEGDEKFQLILTNP 3050
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 24/174 (13%)
Query: 406 VSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVV 465
++K+ E+ + ++ V L IIR G L N T +G G D G V
Sbjct: 2239 ITKLIVEEPEFNSVK----VNLPIIRNSGTLGNVTVQWVATINGQLATG-DLRVVSGNVT 2293
Query: 466 FKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPS 525
F PG+T + + + ++ DD+ E +E V L ++AS G + + ++ +
Sbjct: 2294 FAPGETIQTLLLEVLADDVPEIEEVIQVQL------TDASGGGTIGLDRIANI------- 2340
Query: 526 TATVTIFDDDHAGIFTFEEPVTHVSESI---GIMEVKVLRTSGARGNVIVPYKT 576
+ +DD G F + V V E + + V R+ G G +++ Y T
Sbjct: 2341 ---IIPANDDPYGTVAFAQMVYRVQEPLERSSCANITVRRSGGHFGRLLLFYST 2391
Score = 43.9 bits (102), Expect = 7e-04
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 424 TVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDD 483
++ LT+IR G V V F E G D +G + F PG + ++DD+
Sbjct: 166 SMPLTLIREKGTY-GMVMVTFEVEGGPNPPDEDLSPVKGNITFPPGRATVIYNLTVLDDE 224
Query: 484 IFEEDENFLVHLSNVKVSSE 503
+ E DE FL+ L +V+ +E
Sbjct: 225 VPENDEIFLIQLKSVEGGAE 244
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/243 (22%), Positives = 93/243 (38%), Gaps = 39/243 (16%)
Query: 400 VTENDPVSKIFFEQGT---------YQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGT 450
+ END IF T Y+ + + ++R G V V ++ +
Sbjct: 3903 IEENDDPRGIFMFHVTRGAGEVITAYEVPPPLNVLQVPVVRLAGSF-GAVNVYWKASPDS 3961
Query: 451 ANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGIL 510
A D++ + G + F I + IIDD FE E F + L +V +D ++
Sbjct: 3962 AGL-EDFKPSHGILEFADKQVTAMIEITIIDDAEFELTETFNISLISVAGGGRLGDDVVV 4020
Query: 511 EANHVSTLACLGSPSTATVTIFDDDHA-GIFTFEEPVTHVSESI------GIMEVKVLRT 563
TV I +D G+F FEE + ES+ + + V+R+
Sbjct: 4021 -----------------TVVIPQNDSPFGVFGFEEKTVMIDESLSSDDPDSYVTLTVVRS 4063
Query: 564 SGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFS 623
G +G V + + TI+ A+ + G L F E K I + E++ F+
Sbjct: 4064 PGGKGTVRLEW-TIDEKAK---HNLSPLNGTLHFDETESQKTIVLHTLQDTVLEEDRRFT 4119
Query: 624 LVL 626
+ L
Sbjct: 4120 IQL 4122
Score = 42.0 bits (97), Expect = 0.003
Identities = 62/266 (23%), Positives = 104/266 (39%), Gaps = 40/266 (15%)
Query: 392 SMHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVD-------- 443
S + + + +ND S + F Q Y E + + ++R + N + D
Sbjct: 248 SRNSIEIIIKKND--SPVRFLQSIYLVPEEDHILIIPVVRGKDNNGNLIGSDEYEVSISY 305
Query: 444 -FRTEDGTANAGSDYEFTE----GTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNV 498
T + TA+A + +F + TVVF P + ++ I+DD I E E+F + L
Sbjct: 306 AVTTGNSTAHAQQNLDFIDLQPNTTVVFPPFIHESHLKFQIVDDTIPEIAESFHIMLLKD 365
Query: 499 KVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHA-GIFT-----FEEPVTHVSES 552
+ + A L SPS VTI +D G+ + FE V +
Sbjct: 366 TLQGD---------------AVLISPSVVQVTIKPNDKPYGVLSFNSVLFERTVIIDEDR 410
Query: 553 IG-IMEVKVLRTSGARGNVIVPYKTIEGTARGG--GEDFEDTCGELEFQNDEIVKIITIR 609
I E+ V+R G GNV + + D + G L F +++ I +
Sbjct: 411 ISRYEEITVVRNGGTHGNVSANWVLTRNSTDPSPVTADIRPSSGVLHFAQGQMLATIPLT 470
Query: 610 IFDREEYEKECSFSLVLEEPKWIRRG 635
+ D ++ +E L+ P IR G
Sbjct: 471 VVD-DDLPEEAEAYLLQILPHTIRGG 495
Score = 42.0 bits (97), Expect = 0.003
Identities = 64/238 (26%), Positives = 98/238 (41%), Gaps = 36/238 (15%)
Query: 400 VTENDPVSKIF----FEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
+ END +F +G Y E +V L IIR G L F+ +R E +N
Sbjct: 766 ILENDDPGGVFEFSPASRGPYVIKEG-ESVELHIIRSRGSLVKQ-FLHYRVEPRDSN--- 820
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHV 515
++ G + FKPG+ + I + D I E DE++ V LS +H
Sbjct: 821 EFYGNTGVLEFKPGEREIVITLLARLDGIPELDEHYWVVLS----------------SHG 864
Query: 516 STLACLGSPSTATVTIF-DDDHAGIFTF--EEPVTHVSESIG----IMEVKVLRTSGARG 568
+ LGS + +TI +DD GI F + + ++ES G V+R G G
Sbjct: 865 ERESKLGSATIVNITILKNDDPHGIIEFVSDGLIVMINESKGDAIYSAVYDVVRNRGNFG 924
Query: 569 NVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
+V V + +D G + F + E K ITI E E+ F+++L
Sbjct: 925 DVSVSWVVSPDFT----QDVFPVQGTVVFGDQEFSKNITIYSLPDEIPEEMEEFTVIL 978
Score = 40.0 bits (92), Expect = 0.010
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 23/180 (12%)
Query: 453 AGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEA 512
A SD G + F+ G+T K + DD+ E +E F++ L +V + SE+
Sbjct: 1503 AKSDLHPISGYLEFRQGETNKSFIISARDDNDEEGEELFILKLVSVYGGARISEEN---- 1558
Query: 513 NHVSTLACLGSPSTATVTIFDDDHA-GIFTFEEP-VTHVSESIGIMEVKVLRTSGARGNV 570
+TA +TI D+A G+F F + ++E + V RT GA V
Sbjct: 1559 ------------TTARLTIQKSDNANGLFGFTGACIPEIAEEGSTISCVVERTRGALDYV 1606
Query: 571 IVPYKTIEGTARGG----GEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
V Y TI G +DF + G + F + +++ I + D + E F + L
Sbjct: 1607 HVFY-TISQIETDGINYLVDDFANASGTITFLPWQRSEVLNIYVLDDDIPELNEYFRVTL 1665
Score = 38.5 bits (88), Expect = 0.030
Identities = 45/186 (24%), Positives = 75/186 (40%), Gaps = 18/186 (9%)
Query: 425 VALTIIRRGGDLTNTVFVDFRTEDGTANAGS--DYEFTEGTVVFKPGDTQKEIRVGIIDD 482
V + + R G D TV+ + + A + D G+V+F G + I + I D
Sbjct: 673 VYIPLHRDGTDGQATVYWSLKPSGFNSKAVTPDDIGPFNGSVLFLSGQSDTTINITIKGD 732
Query: 483 DIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTF 542
DI E +E + L V V ++ + G S + + +DD G+F F
Sbjct: 733 DIPEMNETVTLSLDRVNVENQVLKSGY--------------TSRDLIILENDDPGGVFEF 778
Query: 543 EEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEI 602
P + I E L +RG+++ + R E + +T G LEF+ E
Sbjct: 779 -SPASRGPYVIKEGESVELHIIRSRGSLVKQFLHYRVEPRDSNEFYGNT-GVLEFKPGER 836
Query: 603 VKIITI 608
+IT+
Sbjct: 837 EIVITL 842
Score = 37.7 bits (86), Expect = 0.052
Identities = 52/238 (21%), Positives = 101/238 (42%), Gaps = 34/238 (14%)
Query: 396 VNTEVTENDPVSKIF-FEQGTYQCLENCGT------VALTIIRRGGDLTNTVFVDFRTED 448
V + +ND +F FE+ T E+ + V LT++R G TV +++ ++
Sbjct: 4020 VTVVIPQNDSPFGVFGFEEKTVMIDESLSSDDPDSYVTLTVVRSPGG-KGTVRLEWTIDE 4078
Query: 449 GTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENF---LVHLSNVKVSSEAS 505
A + GT+ F ++QK I + + D + EED F L+ + V++S
Sbjct: 4079 ---KAKHNLSPLNGTLHFDETESQKTIVLHTLQDTVLEEDRRFTIQLISIDEVEISPVKG 4135
Query: 506 EDGILEANHVSTLACLG-SPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS 564
I+ +G +PS+ + I EP + G + ++R
Sbjct: 4136 SASIIIRGDKRASGEVGIAPSSRHILI-----------GEPSAKYN---GTAIISLVRGP 4181
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSF 622
G G V V ++ + +F +T G+L ++++ I+ I+ + ++ +E SF
Sbjct: 4182 GILGEVTVFWRIFPPSV----GEFAETSGKLTMRDEQSAVIVVIQALN-DDIPEEKSF 4234
Score = 35.4 bits (80), Expect = 0.26
Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 19/128 (14%)
Query: 461 EGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLAC 520
+GTVVF + K I + + D+I EE E F V L N ++
Sbjct: 944 QGTVVFGDQEFSKNITIYSLPDEIPEEMEEFTVILLNGTGGAK----------------- 986
Query: 521 LGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGT 580
+G+ +TAT+ I +D I+ E V V E VLR +V Y T +G
Sbjct: 987 VGNRTTATLRIRRNDDP-IYFAEPRVVRVQEG-ETANFTVLRNGSVDVTCMVQYATKDGK 1044
Query: 581 ARGGGEDF 588
A DF
Sbjct: 1045 ATARERDF 1052
Score = 34.3 bits (77), Expect = 0.57
Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 25/159 (15%)
Query: 427 LTIIRRGGDLTNTV--FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDI 484
+T++R GG N +V R + +D + G + F G I + ++DDD+
Sbjct: 417 ITVVRNGGTHGNVSANWVLTRNSTDPSPVTADIRPSSGVLHFAQGQMLATIPLTVVDDDL 476
Query: 485 FEEDENFLVHL--SNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFD-DDHAGIFT 541
EE E +L+ + ++ +E SE P+ I D DD G+ T
Sbjct: 477 PEEAEAYLLQILPHTIRGGAEVSE-----------------PAELLFYIQDSDDVYGLIT 519
Query: 542 F---EEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTI 577
F E S + + R G +G+V + Y +
Sbjct: 520 FFPMENQKIESSPGERYLSLSFTRLGGTKGDVRLLYSVL 558
Score = 34.3 bits (77), Expect = 0.57
Identities = 17/52 (32%), Positives = 31/52 (59%)
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
D+E T++F G+ ++++ V I+DDD E E F V L+N + ++ E+
Sbjct: 5293 DFEEQTLTLIFLDGERERKVSVQILDDDEPEGQEFFYVFLTNPQGGAQIVEE 5344
Score = 32.0 bits (71), Expect = 2.8
Identities = 39/166 (23%), Positives = 67/166 (40%), Gaps = 5/166 (3%)
Query: 480 IDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGI 539
ID I+E ++ + +V ++ A+ ++ + +G +A + +
Sbjct: 3481 IDIFIWEMGQSSFRYFQSVDFAAVNRIHSFTPASGIAHILLIGQDMSALYCWNSERNQFS 3540
Query: 540 FTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTAR-GGGEDFEDTCGELEFQ 598
F E P + + + VK L +S ++ + I A DF + GEL F+
Sbjct: 3541 FVLEVPSAY---DVASVTVKSLNSSKNLIALVGAHSHIYELAYISSHSDFIPSSGELIFE 3597
Query: 599 NDEIVKIITIRIFDREEYEKECSFSLVLEEPK-WIRRGMKGGFTIT 643
E I + I D EKE SF + L+ PK G+ TIT
Sbjct: 3598 PGEREATIAVNILDDTVPEKEESFKVQLKNPKGGAEIGINDSVTIT 3643
>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/232 (29%), Positives = 96/232 (41%), Gaps = 30/232 (12%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFK 467
I E+ Y E+ + +T+ RRG L T F+ T+D TA D+++ T + F
Sbjct: 1775 ICLEKEYYIVDEDSTFLEVTLTRRGY-LGETSFISIGTKDETAKKDKDFKWKTNKQIQFN 1833
Query: 468 PGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTA 527
PG T RV II D+ +E E F + LS +A L P A
Sbjct: 1834 PGQTTATWRVRIIPDNEYETSETFQIILSE------------------PLMAVLEFPEMA 1875
Query: 528 TVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG--- 584
TV I D E + E IG + + V R+ A +IV T +G+A G
Sbjct: 1876 TVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISS 1935
Query: 585 ---GEDF----EDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLEEP 629
D+ ED L F +E K + I D YE+E SFS+ L P
Sbjct: 1936 TVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLP 1987
Score = 52.8 bits (125), Expect = 2e-06
Identities = 60/248 (24%), Positives = 98/248 (39%), Gaps = 34/248 (13%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + S ++ + Y+ E+ G + + + RR GD + + V T G+A
Sbjct: 1878 EIVDPGDESTVYIPEAEYKIEEDIGELLIPV-RRSGDASQELIVICSTRQGSATGTISST 1936
Query: 455 ---SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
SDY E + F +TQK +V IIDD ++EE+E+F VS
Sbjct: 1937 VLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESF-------SVSLRLPVG 1989
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS--- 564
G L A P+T + D + F + HV+ES +EV V R
Sbjct: 1990 GQLGARF---------PTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDL 2040
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFD---REEYEKECS 621
++ V + E + G D+ L+F ++ + I D + E
Sbjct: 2041 SQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDDLGQPTLEGPEK 2100
Query: 622 FSLVLEEP 629
F L+L+ P
Sbjct: 2101 FELLLQMP 2108
>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/232 (29%), Positives = 96/232 (41%), Gaps = 30/232 (12%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFK 467
I E+ Y E+ + +T+ RRG L T F+ T+D TA D+++ T + F
Sbjct: 1775 ICLEKEYYIVDEDSTFLEVTLTRRGY-LGETSFISIGTKDETAKKDKDFKWKTNKQIQFN 1833
Query: 468 PGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTA 527
PG T RV II D+ +E E F + LS +A L P A
Sbjct: 1834 PGQTTATWRVRIIPDNEYETSETFQIILSE------------------PLMAVLEFPEMA 1875
Query: 528 TVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG--- 584
TV I D E + E IG + + V R+ A +IV T +G+A G
Sbjct: 1876 TVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISS 1935
Query: 585 ---GEDF----EDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLEEP 629
D+ ED L F +E K + I D YE+E SFS+ L P
Sbjct: 1936 TVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLP 1987
Score = 52.8 bits (125), Expect = 2e-06
Identities = 60/248 (24%), Positives = 98/248 (39%), Gaps = 34/248 (13%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + S ++ + Y+ E+ G + + + RR GD + + V T G+A
Sbjct: 1878 EIVDPGDESTVYIPEAEYKIEEDIGELLIPV-RRSGDASQELIVICSTRQGSATGTISST 1936
Query: 455 ---SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
SDY E + F +TQK +V IIDD ++EE+E+F VS
Sbjct: 1937 VLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESF-------SVSLRLPVG 1989
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS--- 564
G L A P+T + D + F + HV+ES +EV V R
Sbjct: 1990 GQLGARF---------PTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDL 2040
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFD---REEYEKECS 621
++ V + E + G D+ L+F ++ + I D + E
Sbjct: 2041 SQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDDLGQPTLEGPEK 2100
Query: 622 FSLVLEEP 629
F L+L+ P
Sbjct: 2101 FELLLQMP 2108
>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/232 (29%), Positives = 96/232 (41%), Gaps = 30/232 (12%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFK 467
I E+ Y E+ + +T+ RRG L T F+ T+D TA D+++ T + F
Sbjct: 1775 ICLEKEYYIVDEDSTFLEVTLTRRGY-LGETSFISIGTKDETAKKDKDFKWKTNKQIQFN 1833
Query: 468 PGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTA 527
PG T RV II D+ +E E F + LS +A L P A
Sbjct: 1834 PGQTTATWRVRIIPDNEYETSETFQIILSE------------------PLMAVLEFPEMA 1875
Query: 528 TVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG--- 584
TV I D E + E IG + + V R+ A +IV T +G+A G
Sbjct: 1876 TVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISS 1935
Query: 585 ---GEDF----EDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVLEEP 629
D+ ED L F +E K + I D YE+E SFS+ L P
Sbjct: 1936 TVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLP 1987
Score = 52.8 bits (125), Expect = 2e-06
Identities = 60/248 (24%), Positives = 98/248 (39%), Gaps = 34/248 (13%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + S ++ + Y+ E+ G + + + RR GD + + V T G+A
Sbjct: 1878 EIVDPGDESTVYIPEAEYKIEEDIGELLIPV-RRSGDASQELIVICSTRQGSATGTISST 1936
Query: 455 ---SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
SDY E + F +TQK +V IIDD ++EE+E+F VS
Sbjct: 1937 VLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESF-------SVSLRLPVG 1989
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS--- 564
G L A P+T + D + F + HV+ES +EV V R
Sbjct: 1990 GQLGARF---------PTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDL 2040
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFD---REEYEKECS 621
++ V + E + G D+ L+F ++ + I D + E
Sbjct: 2041 SQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDDLGQPTLEGPEK 2100
Query: 622 FSLVLEEP 629
F L+L+ P
Sbjct: 2101 FELLLQMP 2108
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 69.3 bits (168), Expect = 2e-11
Identities = 65/242 (26%), Positives = 98/242 (40%), Gaps = 39/242 (16%)
Query: 407 SKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS---------DY 457
S I F+ +Y E G+V++T+ +R G+L V RTE GTA++ S DY
Sbjct: 2552 SLISFKYTSYNVSEKAGSVSVTV-QRTGNLNQYAIVLCRTEQGTASSSSRVSSQPGQQDY 2610
Query: 458 EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVST 517
G V F + K + I DDD+FE E+F V LS +
Sbjct: 2611 VEYAGQVQFDEREDTKSCTIVINDDDVFENVESFTVELS------------------MPA 2652
Query: 518 LACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTI 577
A LG + A V I D + F++ + V+ES G + + R A V T+
Sbjct: 2653 YALLGEFTQAKVIINDTEDEPTLEFDKKIYWVNESAGFLFAPIERKGDASSIVSAICYTV 2712
Query: 578 EGTARG-------GGEDFE----DTCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
+A G G DF+ + F + + + D EYE+E F + L
Sbjct: 2713 PKSAMGSSLYALESGSDFKSRGMSAASRVIFGPGVTMSTCDVMLIDDSEYEEEEEFEIAL 2772
Query: 627 EE 628
+
Sbjct: 2773 AD 2774
Score = 68.2 bits (165), Expect = 4e-11
Identities = 80/277 (28%), Positives = 118/277 (42%), Gaps = 33/277 (11%)
Query: 430 IRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGT----VVFKPGDTQKEIRVGIIDDDIF 485
I R GDL+ V T+ +A D+E + + F GD K V I DD +F
Sbjct: 2940 ITRSGDLSYESSVRCYTQSHSAQVMEDFEERQNADSSRITFLKGDKVKNCTVYIHDDSMF 2999
Query: 486 EEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEP 545
E +E F V+L G+ NH S A +G + AT+TI +D+ A FEE
Sbjct: 3000 EPEEQFRVYL------------GLPLGNHWSG-ARIGKNNMATITISNDEDAPTIEFEEA 3046
Query: 546 VTHVSE-----SIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
V E +I I+ +KV+R V T +G+A+ G D+ L+F
Sbjct: 3047 AYQVREPAGPDAIAILNIKVIRRGDQNRTSKVRCSTRDGSAQ-SGVDYYPKSRVLKFSPG 3105
Query: 601 EIVKIITIRIFDREEYEKECSFSLVL--EEPKWIRRG--MKGGFTITGQPVFRKVHAREH 656
+ I E+ E SFSLVL ++P G TI Q +
Sbjct: 3106 VDHIFFKVEILSNEDREWHESFSLVLGPDDPVEAVLGDVTTATVTILDQEAAGSLILPAP 3165
Query: 657 PILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPIL 693
PI V+T+AD YD + +T +E ++ G P++
Sbjct: 3166 PI---VVTLAD-YDHVEEVT--KEGVKKSPSPGYPLV 3196
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 20/150 (13%)
Query: 400 VTENDPVSKIFFEQGTYQCLENCGTVALTIIR----RGGDLTNTVFVDFRTEDGTANAGS 455
++ ++ I FE+ YQ E G A+ I+ R GD T V T DG+A +G
Sbjct: 3032 ISNDEDAPTIEFEEAAYQVREPAGPDAIAILNIKVIRRGDQNRTSKVRCSTRDGSAQSGV 3091
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHV 515
DY + F PG +V I+ ++ E E+F + L D +E
Sbjct: 3092 DYYPKSRVLKFSPGVDHIFFKVEILSNEDREWHESFSLVL---------GPDDPVE---- 3138
Query: 516 STLACLGSPSTATVTIFDDDHAGIFTFEEP 545
A LG +TATVTI D + AG P
Sbjct: 3139 ---AVLGDVTTATVTILDQEAAGSLILPAP 3165
Score = 48.1 bits (113), Expect = 4e-05
Identities = 56/231 (24%), Positives = 96/231 (41%), Gaps = 35/231 (15%)
Query: 401 TENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFT 460
TE++P + F++ Y E+ G + I R+G D ++ V T +A S Y
Sbjct: 2669 TEDEPTLE--FDKKIYWVNESAGFLFAPIERKG-DASSIVSAICYTVPKSAMGSSLYALE 2725
Query: 461 EGT------------VVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDG 508
G+ V+F PG T V +IDD +EE+E F + L+ +AS++
Sbjct: 2726 SGSDFKSRGMSAASRVIFGPGVTMSTCDVMLIDDSEYEEEEEFEIALA------DASDN- 2778
Query: 509 ILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS---G 565
A +G +TA V I + A + VSE G +++ V+R
Sbjct: 2779 ----------ARIGRVATAKVLISGPNDASTVSLGNTAFTVSEDAGTVKIPVIRHGTDLS 2828
Query: 566 ARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEY 616
+V + + + G D+ + ++EF I + T+ I D +Y
Sbjct: 2829 TFASVWCATRPSDPASATPGVDYVPSSRKVEFGPGVIEQYCTLTILDDTQY 2879
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/256 (22%), Positives = 105/256 (41%), Gaps = 31/256 (12%)
Query: 395 EVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVD--FRTEDGTAN 452
E+ T + V + + GT + + N G L + G TN + + T +
Sbjct: 2418 EIMTAAPQPFRVDILPVDDGTPRIVTNLGLQWLEYM--DGKATNLITKKELLTMDPDTED 2475
Query: 453 AGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDEN-----FLVHLSNVKVSSEASED 507
A YE T G K G + +++ G +ED N +++H ++ ++ +
Sbjct: 2476 AQLVYEITTGP---KHGFVENKLQPGRAAATFTQEDVNLGLIRYVLHKEKIREMMDSFQF 2532
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGAR 567
+ ++ P+ + +F + + +F+ +VSE G + V V RT
Sbjct: 2533 LVKDSK----------PNVVSDNVFHIQWS-LISFKYTSYNVSEKAGSVSVTVQRTGNLN 2581
Query: 568 GNVIVPYKTIEGTARG--------GGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKE 619
IV +T +GTA G +D+ + G+++F E K TI I D + +E
Sbjct: 2582 QYAIVLCRTEQGTASSSSRVSSQPGQQDYVEYAGQVQFDEREDTKSCTIVINDDDVFENV 2641
Query: 620 CSFSLVLEEPKWIRRG 635
SF++ L P + G
Sbjct: 2642 ESFTVELSMPAYALLG 2657
>gi|79749430 FRAS1-related extracellular matrix protein 2 precursor
[Homo sapiens]
Length = 3169
Score = 68.6 bits (166), Expect = 3e-11
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 30/219 (13%)
Query: 429 IIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFKPGDTQKEIRVGIIDDDIFEE 487
+++R G L T F+ T D TA D++ + V F PG T+ RV I+ D E+
Sbjct: 1790 VLKRRGYLGETSFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILSDGEHEQ 1849
Query: 488 DENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVT 547
E F V LS LA L P+ ATV I D +
Sbjct: 1850 SETFQVVLSE------------------PVLAALEFPTVATVEIVDPGDEPTVFIPQSKY 1891
Query: 548 HVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARG-------GGEDF----EDTCGELE 596
V E +G + + + R+ ++V T +GTA G D+ ED +
Sbjct: 1892 SVEEDVGELFIPIRRSGDVSQELMVVCYTQQGTATGTVPTSVLSYSDYISRPEDHTSVVR 1951
Query: 597 FQNDEIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRG 635
F DE K+ I I D YE+E +F ++L P R G
Sbjct: 1952 FDKDEREKLCRIVIIDDSLYEEEETFHVLLSMPMGGRIG 1990
Score = 62.8 bits (151), Expect = 2e-09
Identities = 66/249 (26%), Positives = 98/249 (39%), Gaps = 35/249 (14%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + +F Q Y E+ G + + I RR GD++ + V T+ GTA
Sbjct: 1874 EIVDPGDEPTVFIPQSKYSVEEDVGELFIPI-RRSGDVSQELMVVCYTQQGTATGTVPTS 1932
Query: 455 ----SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASE 506
SDY E V F + +K R+ IIDD ++EE+E F V LS SE
Sbjct: 1933 VLSYSDYISRPEDHTSVVRFDKDEREKLCRIVIIDDSLYEEEETFHVLLSMPMGGRIGSE 1992
Query: 507 DGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS-- 564
P + D D IF F + V ES G +EV+V RT
Sbjct: 1993 ----------------FPGAQVTIVPDKDDEPIFYFGDVEYSVDESAGYVEVQVWRTGTD 2036
Query: 565 -GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQ---NDEIVKIITIRIFDREEYEKEC 620
+V V + + + G D+ L+F N + V+++ + + E
Sbjct: 2037 LSKSSSVTVRSRKTDPPSADAGTDYVGISRNLDFAPGVNMQPVRVVILDDLGQPALEGIE 2096
Query: 621 SFSLVLEEP 629
F LVL P
Sbjct: 2097 KFELVLRMP 2105
Score = 62.4 bits (150), Expect = 2e-09
Identities = 59/218 (27%), Positives = 99/218 (45%), Gaps = 17/218 (7%)
Query: 400 VTENDPVS---KIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSD 456
V+ ND VS K+ F++ Y E+ G + +T+I R GD+ V T G+A D
Sbjct: 2118 VSINDSVSDLPKMQFKERIYTGSESDGQI-VTMIHRTGDVQYRSSVRCYTRQGSAQVMMD 2176
Query: 457 YEFTEGT----VVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEA 512
+E T + F PG+T+K + ++DD ++EE E + L + +S G
Sbjct: 2177 FEERPNTDTSIITFLPGETEKPCILELMDDVLYEEVEELRLVLGTPQSNSPF---GAAVG 2233
Query: 513 NHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIV 572
TL + + TV F + + +EP ES+ ++ + V+R IV
Sbjct: 2234 EQNETLIRIRDDADKTVIKFGETKFSVTEPKEP----GESV-VIRIPVIRQGDTSKVSIV 2288
Query: 573 PYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRI 610
T +G+A GED+ E+EF+ E ++ I +
Sbjct: 2289 RVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHVVEIEV 2325
Score = 54.3 bits (129), Expect = 5e-07
Identities = 66/244 (27%), Positives = 101/244 (41%), Gaps = 30/244 (12%)
Query: 398 TEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFR---TEDGTANAG 454
T V + D +F Y E+ G V + + R G DL+ + V R T+ +A+AG
Sbjct: 1999 TIVPDKDDEPIFYFGDVEYSVDESAGYVEVQVWRTGTDLSKSSSVTVRSRKTDPPSADAG 2058
Query: 455 SDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANH 514
+DY + F PG + +RV I+DD + + +GI +
Sbjct: 2059 TDYVGISRNLDFAPGVNMQPVRVVILDD------------------LGQPALEGIEKFEL 2100
Query: 515 VSTL---ACLGSPSTATVTIFDD-DHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNV 570
V + A LG PS ATV+I D F+E + SES G + + RT +
Sbjct: 2101 VLRMPMNAALGEPSKATVSINDSVSDLPKMQFKERIYTGSESDGQIVTMIHRTGDVQYRS 2160
Query: 571 IVPYKTIEGTARGGGEDFED----TCGELEFQNDEIVKIITIRIFDREEYEKECSFSLVL 626
V T +G+A+ DFE+ + F E K + + D YE+ LVL
Sbjct: 2161 SVRCYTRQGSAQ-VMMDFEERPNTDTSIITFLPGETEKPCILELMDDVLYEEVEELRLVL 2219
Query: 627 EEPK 630
P+
Sbjct: 2220 GTPQ 2223
Score = 47.8 bits (112), Expect = 5e-05
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 6/115 (5%)
Query: 425 VALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDI 484
+ + +IR+G D + V T+DG+A +G DY + FK G+TQ + + + D +
Sbjct: 2272 IRIPVIRQG-DTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHVVEIEVTFDGV 2330
Query: 485 FEEDENFLVHL--SNVKVSSEASEDGILEANHVSTLACLGSPST---ATVTIFDD 534
E E F VHL ++ I+ +S++A + PS ++ ++DD
Sbjct: 2331 REMREAFTVHLKPDENMIAEMQLTKAIVYIEEMSSMADVTFPSVPQIVSLLMYDD 2385
>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 3 [Homo sapiens]
Length = 644
Score = 68.2 bits (165), Expect = 4e-11
Identities = 51/177 (28%), Positives = 83/177 (46%), Gaps = 14/177 (7%)
Query: 745 EDDDDDECGEEKLPSCFDYVMHFL-TVFWK-------VLFAFVPPTEY--WNGW--ACFI 792
E++++DE +E + FD L TV W VL+ VP W W F
Sbjct: 422 EEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFA 481
Query: 793 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 852
S L I + + + + G T+G+ D + + F+A GTSVPD AS + A Q D
Sbjct: 482 SSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGM-GDM 540
Query: 853 SIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINV 909
++ N GSN ++ +G+G+ W++ + G +++ L +SV L F+ V
Sbjct: 541 AVSNSIGSNVFDILIGLGLPWALQTL-AVDYGSYIRLNSRGLIYSVGLLLASVFVTV 596
Score = 58.5 bits (140), Expect = 3e-08
Identities = 65/243 (26%), Positives = 100/243 (41%), Gaps = 48/243 (19%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 112 LHVLCAIYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 153
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSSAPE+ SVI V T GD+G TIVGSA FN+ II +C
Sbjct: 154 FMAAGSSAPELFTSVIGVF---ITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ------ 204
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGV------VEVWEGLLTFFFFPICVVFAWVA 252
++W + + +Y LSVI+ V V WE L+ + I +V
Sbjct: 205 -----VVALSSWCLLRDS-IYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVI---- 254
Query: 253 DRRLLFYKYVYKRY-RAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLE 311
+ + +++ + R K G ++ + D VV NF A V+
Sbjct: 255 ---MKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIM 311
Query: 312 VDE 314
VDE
Sbjct: 312 VDE 314
Score = 35.4 bits (80), Expect = 0.26
Identities = 33/139 (23%), Positives = 54/139 (38%), Gaps = 21/139 (15%)
Query: 818 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 877
L + V F+A G+S P+ F S + + D +G + GS N+ IGV A
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITK-GDVGVGTIVGSAVFNILCIIGVCGLFA- 202
Query: 878 IYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCL 937
G+ +S L +T+ + I + V +Y + S +
Sbjct: 203 ------GQVVALSSWCLLRDSIYYTL-SVIALIVFIYDEK------------VSWWESLV 243
Query: 938 FVLLWLLYIFFSSLEAYCH 956
VL++L+YI A H
Sbjct: 244 LVLMYLIYIVIMKYNACIH 262
>gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo
sapiens]
Length = 558
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q
Sbjct: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451
Query: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900
D ++ N GSN ++ +G+GV W + + G K++ L +SV L
Sbjct: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 38 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 79
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++
Sbjct: 80 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 134
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242
++ S++ + +++ I + WEGL+ +
Sbjct: 135 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 174
Score = 36.6 bits (83), Expect = 0.12
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 818 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 877
L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A
Sbjct: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129
Query: 878 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 907
+ V ++ +++++ + FI
Sbjct: 130 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 157
>gi|29788985 solute carrier family 24 member 4 isoform 2 precursor
[Homo sapiens]
Length = 586
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q
Sbjct: 421 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 479
Query: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900
D ++ N GSN ++ +G+GV W + + G K++ L +SV L
Sbjct: 480 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 528
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/226 (23%), Positives = 96/226 (42%), Gaps = 29/226 (12%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 85 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 126
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++
Sbjct: 127 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 181
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLF 258
++ S++ + +++ I + WEGL+ + ++ + F
Sbjct: 182 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 237
Query: 259 YKYVYKRYRAGKQRGMIIEHEGDRPS-SKTEIEMDGKVVNSHVENF 303
+ K G +E ++P K + M ++++S F
Sbjct: 238 FTVKQKSIANGNPVNSELEAVKEKPQYGKNPVVMVDEIMSSSPPKF 283
Score = 36.6 bits (83), Expect = 0.12
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 818 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 877
L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A
Sbjct: 118 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 176
Query: 878 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 907
+ V ++ +++++ + FI
Sbjct: 177 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 204
>gi|24111228 solute carrier family 24 member 4 isoform 1 precursor
[Homo sapiens]
Length = 605
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q
Sbjct: 440 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 498
Query: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900
D ++ N GSN ++ +G+GV W + + G K++ L +SV L
Sbjct: 499 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 547
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 85 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 126
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++
Sbjct: 127 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 181
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242
++ S++ + +++ I + WEGL+ +
Sbjct: 182 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 221
Score = 36.6 bits (83), Expect = 0.12
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 818 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 877
L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A
Sbjct: 118 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 176
Query: 878 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 907
+ V ++ +++++ + FI
Sbjct: 177 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 204
>gi|45504369 solute carrier family 24, member 5 [Homo sapiens]
Length = 500
Score = 63.5 bits (153), Expect = 9e-10
Identities = 50/169 (29%), Positives = 82/169 (48%), Gaps = 28/169 (16%)
Query: 80 VYFVAMVYMFLGVSIIADR-FMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
+YF+ +VYMF+ +SI+ D F+ S+E+I+ ++ V+ T
Sbjct: 71 IYFLIIVYMFMAISIVCDEYFLPSLEIISESLG------------------LSQDVAGTT 112
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSSAPE++ + + V T GD+G STI+GSA +N+ I A C + +
Sbjct: 113 FMAAGSSAPELVTAFLGVF---ITKGDIGISTILGSAIYNLLGICAACGLL--SNTVSTL 167
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVV 247
+F AA++I A +L +I V +EG L + + V+
Sbjct: 168 SCWPLFRDCAAYTISAAA----VLGIIYDNQVYWYEGALLLLIYGLYVL 212
Score = 52.0 bits (123), Expect = 3e-06
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 15/153 (9%)
Query: 770 VFW-------KVLFAFVPPT--EYWNGW--ACFIVSILMIGLLTAFIGDLASHFGCTIGL 818
+FW +LF P ++W + F +S + I T + + + G T+ +
Sbjct: 306 IFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGETLEI 365
Query: 819 KDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSI--A 876
D+V + +A GTS+PDT AS + A + + D ++ N+ GSN ++ L +G+ W I A
Sbjct: 366 PDTVMGLTLLAAGTSIPDTIASVLVARKGK-GDMAMSNIVGSNVFDM-LCLGIPWFIKTA 423
Query: 877 AIYHAANGEQFKVSPGTLAFSVTLFTIFAFINV 909
I +A E + S+ + IF F+ V
Sbjct: 424 FINGSAPAEVNSRGLTYITISLNISIIFLFLAV 456
Score = 35.8 bits (81), Expect = 0.20
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Query: 99 FMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCG 158
FMS+I + + + GET + +TV LTL+A G+S P+ + SV+
Sbjct: 339 FMSAIWISAFTYILVWMVTITGETLEIP-----DTVMGLTLLAAGTSIPDTIASVLVA-- 391
Query: 159 HNFTAGDLGPSTIVGSAAFNMFII 182
GD+ S IVGS F+M +
Sbjct: 392 -RKGKGDMAMSNIVGSNVFDMLCL 414
>gi|9966787 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 2 [Homo sapiens]
Length = 661
Score = 58.5 bits (140), Expect = 3e-08
Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 38/175 (21%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + M+YMF+ ++I+ D F + S+ VIT +++ I ++ V+ T
Sbjct: 137 LHVIGMIYMFIALAIVCDEFFVPSLTVIT---EKLGI---------------SDDVAGAT 178
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA G SAPE+ S+I V ++G TIVGSA FN+ +I +C +R+I
Sbjct: 179 FMAAGGSAPELFTSLIGVF---IAHSNVGIGTIVGSAVFNILFVIGMCALF-----SREI 230
Query: 199 KHLRVFFVTAAWSIFAYTWLYII-----LSVISPGVVEVWEGLLTFFFFPICVVF 248
+L W +F YI+ + V+ WE LL + VVF
Sbjct: 231 LNL------TWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVF 279
Score = 50.4 bits (119), Expect = 8e-06
Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Query: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
F SI I + + + A G TIG+ + + + +A GTS+PD S + A +
Sbjct: 503 FFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKG-LG 561
Query: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG 910
D ++ + GSN ++ +G+ + W + + H S G V LF + F+ +
Sbjct: 562 DMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQPVAVS-SNGLFCAIVLLFIMLLFVILS 620
Query: 911 VLLYRRR 917
+ L + R
Sbjct: 621 IALCKWR 627
Score = 35.4 bits (80), Expect = 0.26
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 816 IGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGV 871
+G+ D V F+A G S P+ F S + +++ IG + GS N+ IG+
Sbjct: 168 LGISDDVAGATFMAAGGSAPELFTSLIGVF-IAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 32.0 bits (71), Expect = 2.8
Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 131 NETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
+E + LT++A G+S P+++ SVI GD+ S+ VGS F++ + + L
Sbjct: 531 SEEIMGLTILAAGTSIPDLITSVIVA---RKGLGDMAVSSSVGSNIFDITVGLPL 582
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 50.8 bits (120), Expect = 6e-06
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 396 VNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
VN + + + FEQ + + +IRR D + V +RT+DGTA
Sbjct: 979 VNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQ-VSYRTQDGTAQGNR 1037
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIID----DDIF--EEDENFLVHLSNVKVSSEASEDGI 509
DY EG ++F+PG+ KE++V +++ D + + F V LSN K
Sbjct: 1038 DYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFG-------- 1089
Query: 510 LEANHVSTLACLGSPSTATVTIFDDD 535
A LG P + T+ I D D
Sbjct: 1090 ---------AHLGQPHSTTIIIRDPD 1106
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 441 FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKV 500
F D + G +D + G V F+ G ++RV + ++++ LV +V
Sbjct: 911 FHDLKVAPGYYTLTADQD-ARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPA 969
Query: 501 SSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKV 560
+ A LG +TI + + +FE+P VS + + V
Sbjct: 970 GT----------------ATLGR-RLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPV 1012
Query: 561 LRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYE 617
+R G V Y+T +GTA+ G D+ GEL FQ E K + +++ + +E +
Sbjct: 1013 IRRVLDGGKSQVSYRTQDGTAQ-GNRDYIPVEGELLFQPGEAWKELQVKLLELQEVD 1068
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 50.8 bits (120), Expect = 6e-06
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 396 VNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
VN + + + FEQ + + +IRR D + V +RT+DGTA
Sbjct: 979 VNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQ-VSYRTQDGTAQGNR 1037
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIID----DDIF--EEDENFLVHLSNVKVSSEASEDGI 509
DY EG ++F+PG+ KE++V +++ D + + F V LSN K
Sbjct: 1038 DYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFG-------- 1089
Query: 510 LEANHVSTLACLGSPSTATVTIFDDD 535
A LG P + T+ I D D
Sbjct: 1090 ---------AHLGQPHSTTIIIRDPD 1106
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 441 FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKV 500
F D + G +D + G V F+ G ++RV + ++++ LV +V
Sbjct: 911 FHDLKVAPGYYTLTADQD-ARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPA 969
Query: 501 SSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKV 560
+ A LG +TI + + +FE+P VS + + V
Sbjct: 970 GT----------------ATLGR-RLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPV 1012
Query: 561 LRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYE 617
+R G V Y+T +GTA+ G D+ GEL FQ E K + +++ + +E +
Sbjct: 1013 IRRVLDGGKSQVSYRTQDGTAQ-GNRDYIPVEGELLFQPGEAWKELQVKLLELQEVD 1068
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 50.8 bits (120), Expect = 6e-06
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 396 VNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
VN + + + FEQ + + +IRR D + V +RT+DGTA
Sbjct: 979 VNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQ-VSYRTQDGTAQGNR 1037
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIID----DDIF--EEDENFLVHLSNVKVSSEASEDGI 509
DY EG ++F+PG+ KE++V +++ D + + F V LSN K
Sbjct: 1038 DYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFG-------- 1089
Query: 510 LEANHVSTLACLGSPSTATVTIFDDD 535
A LG P + T+ I D D
Sbjct: 1090 ---------AHLGQPHSTTIIIRDPD 1106
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 441 FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKV 500
F D + G +D + G V F+ G ++RV + ++++ LV +V
Sbjct: 911 FHDLKVAPGYYTLTADQD-ARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPA 969
Query: 501 SSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKV 560
+ A LG +TI + + +FE+P VS + + V
Sbjct: 970 GT----------------ATLGR-RLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPV 1012
Query: 561 LRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYE 617
+R G V Y+T +GTA+ G D+ GEL FQ E K + +++ + +E +
Sbjct: 1013 IRRVLDGGKSQVSYRTQDGTAQ-GNRDYIPVEGELLFQPGEAWKELQVKLLELQEVD 1068
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 50.8 bits (120), Expect = 6e-06
Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 28/168 (16%)
Query: 80 VYFVAMVYMFLGVSIIADR-FMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ M+Y+F+ ++I+ D F+ ++ VIT + + +E V+ T
Sbjct: 457 LHVFGMMYVFVALAIVCDEYFVPALGVITDKLQI------------------SEDVAGAT 498
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA G SAPE+ S+I V + ++G TIVGSA FN+ +I C +R+I
Sbjct: 499 FMAAGGSAPELFTSLIGVF---ISHSNVGIGTIVGSAVFNILFVIGTCSLF-----SREI 550
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICV 246
+L + + S + + +IL + ++ WE LL + V
Sbjct: 551 LNLTWWPLFRDVSFYILDLIMLILFFLD-SLIAWWESLLLLLAYAFYV 597
Score = 49.7 bits (117), Expect = 1e-05
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
Query: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
F+ SI+ I + + + A G TIG+ + + + +A GTS+PD S + A +
Sbjct: 941 FLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKG-LG 999
Query: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFI 907
D ++ + GSN ++ +G+ V W + ++ + S G V LF + F+
Sbjct: 1000 DMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVS-SNGLFCAIVLLFLMLLFV 1055
Score = 31.6 bits (70), Expect = 3.7
Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 131 NETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFI 181
+E + LT++A G+S P+++ SVI GD+ S+ VGS F++ +
Sbjct: 969 SEEIMGLTILAAGTSIPDLITSVIVA---RKGLGDMAVSSSVGSNIFDITV 1016
Score = 30.8 bits (68), Expect = 6.3
Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 818 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIG 870
+ + V F+A G S P+ F S + +++ IG + GS N+ IG
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVF-ISHSNVGIGTIVGSAVFNILFVIG 541
>gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]
Length = 2179
Score = 45.1 bits (105), Expect = 3e-04
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Query: 407 SKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVV- 465
S I + Q Y+ EN G + L IIRRG + ++ FV + +A G D+ ++
Sbjct: 1741 SHIEWSQTEYEVCENVGLLPLEIIRRGYSM-DSAFVGIKVNQVSAAVGKDFTVIPSKLIQ 1799
Query: 466 FKPGDTQKEIRVGIIDDDIFEEDENFLVHLSN 497
F PG + K + I D + E+DE F V L++
Sbjct: 1800 FDPGMSTKMWNIAITYDGLEEDDEVFEVILNS 1831
>gi|39995086 solute carrier family 24 member 6 [Homo sapiens]
Length = 584
Score = 36.6 bits (83), Expect = 0.12
Identities = 37/157 (23%), Positives = 68/157 (43%), Gaps = 17/157 (10%)
Query: 775 LFAFVPPT------EYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFV 828
+F PP+ + W ++ IL + F +L++ T+ L +V V F+
Sbjct: 87 IFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSA-ISTTLKLSHNVAGVTFL 145
Query: 829 ALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFK 888
A G PD F++ VA + A ++G + G+ V V + +I + AA+ F+
Sbjct: 146 AFGNGAPDIFSALVAFSDPHTAGLALGALFGA-GVLVTTVVAGGITILHPFMAASRPFFR 204
Query: 889 VSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELG 925
+ + V +F F ++L+R R + LG
Sbjct: 205 ---DIVFYMVAVFLTF------LMLFRGRVTLAWALG 232
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 36.2 bits (82), Expect = 0.15
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 27/105 (25%)
Query: 675 LTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQ 734
LT EEEE R E RP YE K +K++K++N + V Q
Sbjct: 467 LTGIEEEEERAQEHSRP--------------EYETK-VREKMLKESNQSAV--------Q 503
Query: 735 FIEAITVSAGEDDDDDE-CGEEKLPSCFDYVMHFLTVFWKVLFAF 778
+E T G++DD+D+ +++ P Y+M+F ++ + + F
Sbjct: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMIALTF 545
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,879,303
Number of Sequences: 37866
Number of extensions: 1549175
Number of successful extensions: 4681
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 4460
Number of HSP's gapped (non-prelim): 136
length of query: 960
length of database: 18,247,518
effective HSP length: 112
effective length of query: 848
effective length of database: 14,006,526
effective search space: 11877534048
effective search space used: 11877534048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.