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Search of human proteins with 161333839
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|161333839 activin A receptor, type IC isoform 4 [Homo
sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|161333839 activin A receptor, type IC isoform 4 [Homo sapiens] 691 0.0
gi|161333837 activin A receptor, type IC isoform 3 [Homo sapiens] 482 e-136
gi|161333835 activin A receptor, type IC isoform 2 [Homo sapiens] 482 e-136
gi|161333833 activin A receptor, type IC isoform 1 [Homo sapiens] 482 e-136
gi|4759226 transforming growth factor, beta receptor I isoform 1... 395 e-110
gi|195963412 transforming growth factor, beta receptor I isoform... 395 e-110
gi|4757720 activin A receptor, type IB isoform a precursor [Homo... 391 e-109
gi|33598910 activin A receptor, type IB isoform b precursor [Hom... 323 2e-88
gi|4502431 bone morphogenetic protein receptor, type IB precurso... 310 1e-84
gi|41349437 bone morphogenetic protein receptor, type IA precurs... 300 9e-82
gi|166235898 activin A receptor, type I precursor [Homo sapiens] 293 1e-79
gi|4501895 activin A receptor, type I precursor [Homo sapiens] 293 1e-79
gi|116734714 activin A receptor type II-like 1 [Homo sapiens] 269 2e-72
gi|116734712 activin A receptor type II-like 1 [Homo sapiens] 269 2e-72
gi|33598912 activin A receptor, type IB isoform c precursor [Hom... 246 3e-65
gi|67782324 transforming growth factor, beta receptor II isoform... 177 1e-44
gi|67782326 transforming growth factor, beta receptor II isoform... 177 1e-44
gi|4501897 activin A receptor, type IIA precursor [Homo sapiens] 174 8e-44
gi|116734708 activin A receptor, type IIB precursor [Homo sapiens] 165 5e-41
gi|15451916 bone morphogenetic protein receptor type II precurso... 146 2e-35
gi|10198656 anti-Mullerian hormone receptor, type II [Homo sapiens] 134 1e-31
gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinas... 70 3e-12
gi|19526767 MLK-related kinase isoform 2 [Homo sapiens] 67 2e-11
gi|82880648 MLK-related kinase isoform 1 [Homo sapiens] 67 2e-11
gi|187475373 c-src tyrosine kinase [Homo sapiens] 65 1e-10
gi|4758078 c-src tyrosine kinase [Homo sapiens] 65 1e-10
gi|110349799 testis-specific protein kinase 2 [Homo sapiens] 64 2e-10
gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens] 62 7e-10
gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens] 62 7e-10
gi|4885489 v-mos Moloney murine sarcoma viral oncogene homolog [... 60 2e-09
>gi|161333839 activin A receptor, type IC isoform 4 [Homo sapiens]
Length = 336
Score = 691 bits (1782), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI 60
MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI
Sbjct: 1 MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI 60
Query: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTDNGTWTQLWLVSEYHEQGS 120
KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTDNGTWTQLWLVSEYHEQGS
Sbjct: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTDNGTWTQLWLVSEYHEQGS 120
Query: 121 LYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETC 180
LYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETC
Sbjct: 121 LYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETC 180
Query: 181 AIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLV 240
AIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLV
Sbjct: 181 AIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLV 240
Query: 241 YWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVM 300
YWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVM
Sbjct: 241 YWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVM 300
Query: 301 GRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 336
GRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
Sbjct: 301 GRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 336
>gi|161333837 activin A receptor, type IC isoform 3 [Homo sapiens]
Length = 413
Score = 482 bits (1241), Expect = e-136
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA
Sbjct: 179 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 238
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM
Sbjct: 239 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 298
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ
Sbjct: 299 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 358
Query: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 336
KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
Sbjct: 359 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 413
Score = 213 bits (541), Expect = 3e-55
Identities = 101/101 (100%), Positives = 101/101 (100%)
Query: 1 MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI 60
MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI
Sbjct: 1 MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI 60
Query: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT
Sbjct: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
>gi|161333835 activin A receptor, type IC isoform 2 [Homo sapiens]
Length = 443
Score = 482 bits (1241), Expect = e-136
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA
Sbjct: 209 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 268
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM
Sbjct: 269 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 328
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ
Sbjct: 329 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 388
Query: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 336
KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
Sbjct: 389 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 443
Score = 112 bits (280), Expect = 5e-25
Identities = 51/51 (100%), Positives = 51/51 (100%)
Query: 51 MLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
MLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT
Sbjct: 1 MLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 51
>gi|161333833 activin A receptor, type IC isoform 1 [Homo sapiens]
Length = 493
Score = 482 bits (1241), Expect = e-136
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA
Sbjct: 259 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 318
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM
Sbjct: 319 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 378
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ
Sbjct: 379 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 438
Query: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 336
KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
Sbjct: 439 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA 493
Score = 213 bits (541), Expect = 3e-55
Identities = 101/101 (100%), Positives = 101/101 (100%)
Query: 1 MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI 60
MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI
Sbjct: 1 MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI 60
Query: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT
Sbjct: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
>gi|4759226 transforming growth factor, beta receptor I isoform 1
precursor [Homo sapiens]
Length = 503
Score = 395 bits (1015), Expect = e-110
Identities = 189/234 (80%), Positives = 212/234 (90%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVS+YHE GSL+DYLNR VTV GMIKLALS ASGLAHLHMEIVGTQGKPA
Sbjct: 269 DNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPA 328
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRD+KSKNILVKK TC IADLGLAV+HDS +TIDI N +VGTKRYMAPE+LDD++
Sbjct: 329 IAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI 388
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
N+ FESFKRADIY++GLV+WEIARRCS+GGI E+YQLPYYD+VPSDPS+EEMRKVVC+Q
Sbjct: 389 NMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQ 448
Query: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCK 335
K RP+IPN+WQSCEALRVM +IMRECWYANGAARLTALRIKKT+SQL +E K
Sbjct: 449 KLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIK 502
Score = 61.2 bits (147), Expect = 1e-09
Identities = 45/109 (41%), Positives = 53/109 (48%), Gaps = 15/109 (13%)
Query: 4 ALCSALRQALLLL------AAAAELSPG---LKCVCLLCDSSNFTCQTEGACWASVMLTN 54
A +A R LLLL AAAA L PG L+C C LC NFTC T+G C+ SV T
Sbjct: 3 AAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETT 62
Query: 55 GKEQVIKSCVS----LPELNAQVFCHSS--NNVTKTECCFTDFCNNITL 97
K C++ +P V SS +VT T CC D CN I L
Sbjct: 63 DKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
>gi|195963412 transforming growth factor, beta receptor I isoform 2
precursor [Homo sapiens]
Length = 426
Score = 395 bits (1015), Expect = e-110
Identities = 189/234 (80%), Positives = 212/234 (90%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVS+YHE GSL+DYLNR VTV GMIKLALS ASGLAHLHMEIVGTQGKPA
Sbjct: 192 DNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPA 251
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRD+KSKNILVKK TC IADLGLAV+HDS +TIDI N +VGTKRYMAPE+LDD++
Sbjct: 252 IAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI 311
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
N+ FESFKRADIY++GLV+WEIARRCS+GGI E+YQLPYYD+VPSDPS+EEMRKVVC+Q
Sbjct: 312 NMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQ 371
Query: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCK 335
K RP+IPN+WQSCEALRVM +IMRECWYANGAARLTALRIKKT+SQL +E K
Sbjct: 372 KLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIK 425
Score = 61.2 bits (147), Expect = 1e-09
Identities = 45/109 (41%), Positives = 53/109 (48%), Gaps = 15/109 (13%)
Query: 4 ALCSALRQALLLL------AAAAELSPG---LKCVCLLCDSSNFTCQTEGACWASVMLTN 54
A +A R LLLL AAAA L PG L+C C LC NFTC T+G C+ SV T
Sbjct: 3 AAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETT 62
Query: 55 GKEQVIKSCVS----LPELNAQVFCHSS--NNVTKTECCFTDFCNNITL 97
K C++ +P V SS +VT T CC D CN I L
Sbjct: 63 DKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
>gi|4757720 activin A receptor, type IB isoform a precursor [Homo
sapiens]
Length = 505
Score = 391 bits (1004), Expect = e-109
Identities = 187/234 (79%), Positives = 211/234 (90%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVS+YHE GSL+DYLNR VT+ GMIKLALS ASGLAHLHMEIVGTQGKP
Sbjct: 271 DNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPG 330
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRD+KSKNILVKK CAIADLGLAV+HD++ +TIDI N +VGTKRYMAPE+LD+T+
Sbjct: 331 IAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETI 390
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
N+ F+SFK ADIY++GLVYWEIARRC+ GG+ EEYQLPYYD+VPSDPSIEEMRKVVCDQ
Sbjct: 391 NMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQ 450
Query: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCK 335
K RP+IPN WQS EALRVMG++MRECWYANGAARLTALRIKKT+SQL V+ED K
Sbjct: 451 KLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVK 504
Score = 75.5 bits (184), Expect = 6e-14
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 7/96 (7%)
Query: 13 LLLLAAAAELSP----GLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPE 68
+LLLA + P L C C C +N+TC+T+GAC S+ +G E +++C+ E
Sbjct: 15 VLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVE 74
Query: 69 L---NAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
L +C SS ++ T CC+TD+CN I L +P+
Sbjct: 75 LVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPS 110
>gi|33598910 activin A receptor, type IB isoform b precursor [Homo
sapiens]
Length = 476
Score = 323 bits (827), Expect = 2e-88
Identities = 153/194 (78%), Positives = 173/194 (89%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVS+YHE GSL+DYLNR VT+ GMIKLALS ASGLAHLHMEIVGTQGKP
Sbjct: 271 DNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPG 330
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRD+KSKNILVKK CAIADLGLAV+HD++ +TIDI N +VGTKRYMAPE+LD+T+
Sbjct: 331 IAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETI 390
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
N+ F+SFK ADIY++GLVYWEIARRC+ GG+ EEYQLPYYD+VPSDPSIEEMRKVVCDQ
Sbjct: 391 NMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQ 450
Query: 282 KFRPSIPNQWQSCE 295
K RP+IPN WQS E
Sbjct: 451 KLRPNIPNWWQSYE 464
Score = 75.5 bits (184), Expect = 6e-14
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 7/96 (7%)
Query: 13 LLLLAAAAELSP----GLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPE 68
+LLLA + P L C C C +N+TC+T+GAC S+ +G E +++C+ E
Sbjct: 15 VLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVE 74
Query: 69 L---NAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
L +C SS ++ T CC+TD+CN I L +P+
Sbjct: 75 LVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPS 110
>gi|4502431 bone morphogenetic protein receptor, type IB precursor
[Homo sapiens]
Length = 502
Score = 310 bits (794), Expect = 1e-84
Identities = 146/232 (62%), Positives = 181/232 (78%)
Query: 104 GTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIA 163
G+WTQL+L+++YHE GSLYDYL + M+KLA S SGL HLH EI TQGKPAIA
Sbjct: 270 GSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIA 329
Query: 164 HRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNV 223
HRD+KSKNILVKK TC IADLGLAVK S N +DIP N +VGTKRYM PE+LD+++N
Sbjct: 330 HRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNR 389
Query: 224 NIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKF 283
N F+S+ AD+YS GL+ WE+ARRC GGIVEEYQLPY+D+VPSDPS E+MR++VC +K
Sbjct: 390 NHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKL 449
Query: 284 RPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCK 335
RPS PN+W S E LR MG++M ECW N A+RLTALR+KKT++++ +D K
Sbjct: 450 RPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIK 501
>gi|41349437 bone morphogenetic protein receptor, type IA precursor
[Homo sapiens]
Length = 532
Score = 300 bits (769), Expect = 9e-82
Identities = 141/232 (60%), Positives = 181/232 (78%)
Query: 104 GTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIA 163
G+WTQL+L+++YHE GSLYD+L + ++KLA S A GL HLH EI GTQGKPAIA
Sbjct: 300 GSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIA 359
Query: 164 HRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNV 223
HRD+KSKNIL+KK +C IADLGLAVK +S N +D+P N +VGTKRYMAPE+LD+++N
Sbjct: 360 HRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNK 419
Query: 224 NIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKF 283
N F+ + ADIYS GL+ WE+ARRC GGIVEEYQLPYY+MVPSDPS E+MR+VVC ++
Sbjct: 420 NHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRL 479
Query: 284 RPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCK 335
RP + N+W S E LR + ++M ECW N A+RLTALRIKKT++++ +D K
Sbjct: 480 RPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVK 531
Score = 33.1 bits (74), Expect = 0.36
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 18 AAAELSPGLKCVCL-LC--DSSNFTCQTEGACWASVMLTN-GKEQVIKSCVSLPELNAQV 73
A + P LKC C C D+ N TC T G C+A + + G+ + C+ + Q
Sbjct: 51 APEDTLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQC 110
Query: 74 FCHSSNNVTKT-ECCFTDFCN 93
+ +T ECC T+ CN
Sbjct: 111 KDSPKAQLRRTIECCRTNLCN 131
>gi|166235898 activin A receptor, type I precursor [Homo sapiens]
Length = 509
Score = 293 bits (751), Expect = 1e-79
Identities = 140/239 (58%), Positives = 180/239 (75%), Gaps = 5/239 (2%)
Query: 101 TDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKP 160
T + TQLWL++ YHE GSLYDYL + +++ LSIASGLAHLH+EI GTQGKP
Sbjct: 271 TSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKP 330
Query: 161 AIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDT 220
AIAHRD+KSKNILVKK C IADLGLAV H N +D+ NP+VGTKRYMAPE+LD+T
Sbjct: 331 AIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDET 390
Query: 221 MNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCD 280
+ V+ F+S+KR DI++ GLV WE+ARR GIVE+Y+ P+YD+VP+DPS E+MRKVVC
Sbjct: 391 IQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCV 450
Query: 281 QKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL-----CVKEDC 334
+ RP+IPN+W S L + ++M+ECWY N +ARLTALRIKKT++++ +K DC
Sbjct: 451 DQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC 509
>gi|4501895 activin A receptor, type I precursor [Homo sapiens]
Length = 509
Score = 293 bits (751), Expect = 1e-79
Identities = 140/239 (58%), Positives = 180/239 (75%), Gaps = 5/239 (2%)
Query: 101 TDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKP 160
T + TQLWL++ YHE GSLYDYL + +++ LSIASGLAHLH+EI GTQGKP
Sbjct: 271 TSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKP 330
Query: 161 AIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDT 220
AIAHRD+KSKNILVKK C IADLGLAV H N +D+ NP+VGTKRYMAPE+LD+T
Sbjct: 331 AIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDET 390
Query: 221 MNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCD 280
+ V+ F+S+KR DI++ GLV WE+ARR GIVE+Y+ P+YD+VP+DPS E+MRKVVC
Sbjct: 391 IQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCV 450
Query: 281 QKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL-----CVKEDC 334
+ RP+IPN+W S L + ++M+ECWY N +ARLTALRIKKT++++ +K DC
Sbjct: 451 DQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC 509
>gi|116734714 activin A receptor type II-like 1 [Homo sapiens]
Length = 503
Score = 269 bits (688), Expect = 2e-72
Identities = 130/228 (57%), Positives = 169/228 (74%)
Query: 101 TDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKP 160
T + TQLWL++ YHE GSLYD+L R + ++LA+S A GLAHLH+EI GTQGKP
Sbjct: 265 TSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKP 324
Query: 161 AIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDT 220
AIAHRD KS+N+LVK C IADLGLAV H + +DI NP+VGTKRYMAPE+LD+
Sbjct: 325 AIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQ 384
Query: 221 MNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCD 280
+ + FES+K DI++ GLV WEIARR V GIVE+Y+ P+YD+VP+DPS E+M+KVVC
Sbjct: 385 IRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCV 444
Query: 281 QKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
+ P+IPN+ + L + ++MRECWY N +ARLTALRIKKT+ ++
Sbjct: 445 DQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKI 492
>gi|116734712 activin A receptor type II-like 1 [Homo sapiens]
Length = 503
Score = 269 bits (688), Expect = 2e-72
Identities = 130/228 (57%), Positives = 169/228 (74%)
Query: 101 TDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKP 160
T + TQLWL++ YHE GSLYD+L R + ++LA+S A GLAHLH+EI GTQGKP
Sbjct: 265 TSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKP 324
Query: 161 AIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDT 220
AIAHRD KS+N+LVK C IADLGLAV H + +DI NP+VGTKRYMAPE+LD+
Sbjct: 325 AIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQ 384
Query: 221 MNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCD 280
+ + FES+K DI++ GLV WEIARR V GIVE+Y+ P+YD+VP+DPS E+M+KVVC
Sbjct: 385 IRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCV 444
Query: 281 QKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
+ P+IPN+ + L + ++MRECWY N +ARLTALRIKKT+ ++
Sbjct: 445 DQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKI 492
>gi|33598912 activin A receptor, type IB isoform c precursor [Homo
sapiens]
Length = 487
Score = 246 bits (627), Expect = 3e-65
Identities = 117/151 (77%), Positives = 134/151 (88%)
Query: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
DNGTWTQLWLVS+YHE GSL+DYLNR VT+ GMIKLALS ASGLAHLHMEIVGTQGKP
Sbjct: 271 DNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPG 330
Query: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
IAHRD+KSKNILVKK CAIADLGLAV+HD++ +TIDI N +VGTKRYMAPE+LD+T+
Sbjct: 331 IAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETI 390
Query: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGG 252
N+ F+SFK ADIY++GLVYWEIARRC+ GG
Sbjct: 391 NMKHFDSFKCADIYALGLVYWEIARRCNSGG 421
Score = 75.5 bits (184), Expect = 6e-14
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 7/96 (7%)
Query: 13 LLLLAAAAELSP----GLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPE 68
+LLLA + P L C C C +N+TC+T+GAC S+ +G E +++C+ E
Sbjct: 15 VLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVE 74
Query: 69 L---NAQVFCHSSNNVTKTECCFTDFCNNITLHLPT 101
L +C SS ++ T CC+TD+CN I L +P+
Sbjct: 75 LVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPS 110
>gi|67782324 transforming growth factor, beta receptor II isoform B
precursor [Homo sapiens]
Length = 567
Score = 177 bits (449), Expect = 1e-44
Identities = 88/223 (39%), Positives = 139/223 (62%), Gaps = 3/223 (1%)
Query: 108 QLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA--IAHR 165
Q WL++ +H +G+L +YL R++++ + KL S+A G+AHLH + G+P I HR
Sbjct: 320 QYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPC-GRPKMPIVHR 378
Query: 166 DIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNI 225
D+KS NILVK TC + D GL+++ D L+ D+ + +VGT RYMAPE+L+ MN+
Sbjct: 379 DLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLEN 438
Query: 226 FESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRP 285
ESFK+ D+YS+ LV WE+ RC+ G V++Y+ P+ V P +E M+ V + RP
Sbjct: 439 VESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRP 498
Query: 286 SIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
IP+ W + + ++++ + ECW + ARLTA + + S+L
Sbjct: 499 EIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSEL 541
>gi|67782326 transforming growth factor, beta receptor II isoform A
precursor [Homo sapiens]
Length = 592
Score = 177 bits (449), Expect = 1e-44
Identities = 88/223 (39%), Positives = 139/223 (62%), Gaps = 3/223 (1%)
Query: 108 QLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA--IAHR 165
Q WL++ +H +G+L +YL R++++ + KL S+A G+AHLH + G+P I HR
Sbjct: 345 QYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPC-GRPKMPIVHR 403
Query: 166 DIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNI 225
D+KS NILVK TC + D GL+++ D L+ D+ + +VGT RYMAPE+L+ MN+
Sbjct: 404 DLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLEN 463
Query: 226 FESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRP 285
ESFK+ D+YS+ LV WE+ RC+ G V++Y+ P+ V P +E M+ V + RP
Sbjct: 464 VESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRP 523
Query: 286 SIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
IP+ W + + ++++ + ECW + ARLTA + + S+L
Sbjct: 524 EIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSEL 566
>gi|4501897 activin A receptor, type IIA precursor [Homo sapiens]
Length = 513
Score = 174 bits (442), Expect = 8e-44
Identities = 93/223 (41%), Positives = 148/223 (66%), Gaps = 6/223 (2%)
Query: 109 LWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQG--KPAIAHRD 166
LWL++ +HE+GSL D+L N+V+ + +A ++A GLA+LH +I G + KPAI+HRD
Sbjct: 263 LWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRD 322
Query: 167 IKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIF 226
IKSKN+L+K T IAD GLA+K ++ + D + +VGT+RYMAPE+L+ +N
Sbjct: 323 IKSKNVLLKNNLTACIADFGLALKFEAGKSAGDT--HGQVGTRRYMAPEVLEGAINFQR- 379
Query: 227 ESFKRADIYSVGLVYWEIARRCSVG-GIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRP 285
++F R D+Y++GLV WE+A RC+ G V+EY LP+ + + PS+E+M++VV +K RP
Sbjct: 380 DAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRP 439
Query: 286 SIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
+ + WQ + ++ + ECW + ARL+A + + I+Q+
Sbjct: 440 VLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQM 482
>gi|116734708 activin A receptor, type IIB precursor [Homo sapiens]
Length = 512
Score = 165 bits (418), Expect = 5e-41
Identities = 88/223 (39%), Positives = 142/223 (63%), Gaps = 7/223 (3%)
Query: 108 QLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQG---KPAIAH 164
+LWL++ +H++GSL DYL NI+T + +A +++ GL++LH ++ +G KP+IAH
Sbjct: 260 ELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAH 319
Query: 165 RDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVN 224
RD KSKN+L+K T +AD GLAV+ + D + +VGT+RYMAPE+L+ +N
Sbjct: 320 RDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDT--HGQVGTRRYMAPEVLEGAINFQ 377
Query: 225 IFESFKRADIYSVGLVYWEIARRCSVG-GIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKF 283
++F R D+Y++GLV WE+ RC G V+EY LP+ + + PS+EE+++VV +K
Sbjct: 378 R-DAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKM 436
Query: 284 RPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTIS 326
RP+I + W L + + ECW + ARL+A +++ +S
Sbjct: 437 RPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVS 479
Score = 30.0 bits (66), Expect = 3.0
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 12/67 (17%)
Query: 46 CWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTE--------CCFTDFCNNITL 97
C+AS ++G +++K L + N C+ TE CC +FCN
Sbjct: 59 CYASWRNSSGTIELVKKGCWLDDFN----CYDRQECVATEENPQVYFCCCEGNFCNERFT 114
Query: 98 HLPTDNG 104
HLP G
Sbjct: 115 HLPEAGG 121
>gi|15451916 bone morphogenetic protein receptor type II precursor
[Homo sapiens]
Length = 1038
Score = 146 bits (369), Expect = 2e-35
Identities = 88/230 (38%), Positives = 135/230 (58%), Gaps = 14/230 (6%)
Query: 111 LVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIV-GTQGKPAIAHRDIKS 169
LV EY+ GSL YL+ + +LA S+ GLA+LH E+ G KPAI+HRD+ S
Sbjct: 277 LVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNS 336
Query: 170 KNILVKKCETCAIADLGLAVKHDSILNTIDIPQN------PKVGTKRYMAPEMLDDTMNV 223
+N+LVK TC I+D GL+++ N + P +VGT RYMAPE+L+ +N+
Sbjct: 337 RNVLVKNDGTCVISDFGLSMRLTG--NRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNL 394
Query: 224 NIFES-FKRADIYSVGLVYWEIARRCS---VGGIVEEYQLPYYDMVPSDPSIEEMRKVVC 279
ES K+ D+Y++GL+YWEI RC+ G V EYQ+ + V + P+ E+M+ +V
Sbjct: 395 RDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVS 454
Query: 280 DQKFRPSIPNQW-QSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
+K RP P W ++ A+R + + +CW + ARLTA ++ +++L
Sbjct: 455 REKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAEL 504
>gi|10198656 anti-Mullerian hormone receptor, type II [Homo sapiens]
Length = 573
Score = 134 bits (337), Expect = 1e-31
Identities = 87/233 (37%), Positives = 133/233 (57%), Gaps = 16/233 (6%)
Query: 111 LVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEI-VGTQGKPAIAHRDIKS 169
LV E H +GSL YL + +++ALS+A GLA LH E Q KP IAHRD+ S
Sbjct: 277 LVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSS 336
Query: 170 KNILVKKCETCAIADLGLAVKHDSILN----TIDIPQNP----KVGTKRYMAPEMLDDTM 221
+N+L+++ +CAI DLGLA+ + T PQ P + GT+RYMAPE+LD T+
Sbjct: 337 QNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTL 396
Query: 222 NVNIF-ESFKRADIYSVGLVYWEIARRC---SVGGIVEEYQLPYYDMVPSDPSIEEMRKV 277
++ + + +RADIYS+ L+ WEI RC +QL Y + + P+ +E+ +
Sbjct: 397 DLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNTPTSDELWAL 456
Query: 278 VCDQKFRPSIPNQWQSCEALRVMG--RIMRECWYANGAARLTALRIKKTISQL 328
++ RP IP+ W+ C A G ++ +CW A+ ARLTA +++ ++ L
Sbjct: 457 AVQERRRPYIPSTWR-CFATDPDGLRELLEDCWDADPEARLTAECVQQRLAAL 508
>gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinase 1
[Homo sapiens]
Length = 671
Score = 70.1 bits (170), Expect = 3e-12
Identities = 74/244 (30%), Positives = 114/244 (46%), Gaps = 48/244 (19%)
Query: 111 LVSEYHEQGSLYDYLNRNIVTVAGMI-KLALSIASGLAHLHMEIVGTQGKPAIAHRDIKS 169
LV EY E+G+L L + T + ++ L I G+ +LH GK I H+D+K
Sbjct: 90 LVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLH-------GKGVI-HKDLKP 141
Query: 170 KNILVKKCETCAIADLGLAV---------KHDSILNTIDIPQNPKVGTKRYMAPEMLDDT 220
+NILV IADLGLA + + L +D GT YMAPE L+D
Sbjct: 142 ENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLND- 200
Query: 221 MNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCD 280
VN + +++D+YS +V W I + + P + +I E + ++C
Sbjct: 201 --VNA-KPTEKSDVYSFAVVLWAI----------------FANKEPYENAICEQQLIMCI 241
Query: 281 QK-FRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKT-----ISQL--CVKE 332
+ RP + + + C R + +M+ CW AN AR T I++ +SQL V+E
Sbjct: 242 KSGNRPDVDDITEYCP--REIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEE 299
Query: 333 DCKA 336
D K+
Sbjct: 300 DVKS 303
>gi|19526767 MLK-related kinase isoform 2 [Homo sapiens]
Length = 455
Score = 67.0 bits (162), Expect = 2e-11
Identities = 56/208 (26%), Positives = 99/208 (47%), Gaps = 40/208 (19%)
Query: 111 LVSEYHEQGSLYDYLNRN---IVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDI 167
+V+EY GSLYDY+N N + + ++ A +A G+ +LHME + HRD+
Sbjct: 80 IVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME-----APVKVIHRDL 134
Query: 168 KSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFE 227
KS+N+++ I D G + H+ + VGT +MAPE++ ++ + E
Sbjct: 135 KSRNVVIAADGVLKICDFGASRFHNHTTHM------SLVGTFPWMAPEVI---QSLPVSE 185
Query: 228 SFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSI 287
+ D YS G+V WE+ R ++P+ + ++ +V ++ R +I
Sbjct: 186 T---CDTYSYGVVLWEMLTR----------EVPFKGLEGL-----QVAWLVVEKNERLTI 227
Query: 288 PNQWQSCEALRVMGRIMRECWYANGAAR 315
P+ SC R ++ +CW A+ R
Sbjct: 228 PS---SCP--RSFAELLHQCWEADAKKR 250
>gi|82880648 MLK-related kinase isoform 1 [Homo sapiens]
Length = 800
Score = 67.0 bits (162), Expect = 2e-11
Identities = 56/208 (26%), Positives = 99/208 (47%), Gaps = 40/208 (19%)
Query: 111 LVSEYHEQGSLYDYLNRN---IVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDI 167
+V+EY GSLYDY+N N + + ++ A +A G+ +LHME + HRD+
Sbjct: 80 IVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME-----APVKVIHRDL 134
Query: 168 KSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFE 227
KS+N+++ I D G + H+ + VGT +MAPE++ ++ + E
Sbjct: 135 KSRNVVIAADGVLKICDFGASRFHNHTTHM------SLVGTFPWMAPEVI---QSLPVSE 185
Query: 228 SFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSI 287
+ D YS G+V WE+ R ++P+ + ++ +V ++ R +I
Sbjct: 186 T---CDTYSYGVVLWEMLTR----------EVPFKGLEGL-----QVAWLVVEKNERLTI 227
Query: 288 PNQWQSCEALRVMGRIMRECWYANGAAR 315
P+ SC R ++ +CW A+ R
Sbjct: 228 PS---SCP--RSFAELLHQCWEADAKKR 250
>gi|187475373 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 64.7 bits (156), Expect = 1e-10
Identities = 54/227 (23%), Positives = 106/227 (46%), Gaps = 44/227 (19%)
Query: 109 LWLVSEYHEQGSLYDYLNRNIVTVAG---MIKLALSIASGLAHLHMEIVGTQGKPAIAHR 165
L++V+EY +GSL DYL +V G ++K +L + + +L +G + HR
Sbjct: 262 LYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYL-------EGNNFV-HR 313
Query: 166 DIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNI 225
D+ ++N+LV + ++D GL + S +T +P ++ APE L +
Sbjct: 314 DLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWTAPEALREK----- 361
Query: 226 FESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRP 285
+ ++D++S G++ WEI G V ++P D+V P +E+ K+ P
Sbjct: 362 -KFSTKSDVWSFGILLWEIYS----FGRVPYPRIPLKDVV---PRVEKGYKMDAPDGCPP 413
Query: 286 SIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKE 332
++ +M+ CW+ + A R + L++++ + + E
Sbjct: 414 AV-------------YEVMKNCWHLDAAMRPSFLQLREQLEHIKTHE 447
>gi|4758078 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 64.7 bits (156), Expect = 1e-10
Identities = 54/227 (23%), Positives = 106/227 (46%), Gaps = 44/227 (19%)
Query: 109 LWLVSEYHEQGSLYDYLNRNIVTVAG---MIKLALSIASGLAHLHMEIVGTQGKPAIAHR 165
L++V+EY +GSL DYL +V G ++K +L + + +L +G + HR
Sbjct: 262 LYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYL-------EGNNFV-HR 313
Query: 166 DIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNI 225
D+ ++N+LV + ++D GL + S +T +P ++ APE L +
Sbjct: 314 DLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWTAPEALREK----- 361
Query: 226 FESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRP 285
+ ++D++S G++ WEI G V ++P D+V P +E+ K+ P
Sbjct: 362 -KFSTKSDVWSFGILLWEIYS----FGRVPYPRIPLKDVV---PRVEKGYKMDAPDGCPP 413
Query: 286 SIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKE 332
++ +M+ CW+ + A R + L++++ + + E
Sbjct: 414 AV-------------YEVMKNCWHLDAAMRPSFLQLREQLEHIKTHE 447
>gi|110349799 testis-specific protein kinase 2 [Homo sapiens]
Length = 571
Score = 63.5 bits (153), Expect = 2e-10
Identities = 49/145 (33%), Positives = 78/145 (53%), Gaps = 22/145 (15%)
Query: 108 QLWLVSEYHEQGSLYDYLNRNI-VTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRD 166
QL ++EY G+L L+ N+ + +KLA IA GL++LH + I HRD
Sbjct: 125 QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFK--------GIFHRD 176
Query: 167 IKSKNILVKKCE---TCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEML-DDTMN 222
+ SKN L+K+ E + +AD GLA K + ++ + VG+ +MAPE+L D+ N
Sbjct: 177 LTSKNCLIKRDENGYSAVVADFGLAEKIPDV--SMGSEKLAVVGSPFWMAPEVLRDEPYN 234
Query: 223 VNIFESFKRADIYSVGLVYWEIARR 247
++AD++S G++ EI R
Sbjct: 235 -------EKADVFSYGIILCEIIAR 252
>gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]
Length = 431
Score = 62.0 bits (149), Expect = 7e-10
Identities = 45/140 (32%), Positives = 71/140 (50%), Gaps = 18/140 (12%)
Query: 107 TQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRD 166
T+LW++ EY GS D L + + + I GL +LH E HRD
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE--------KKIHRD 144
Query: 167 IKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIF 226
IK+ N+L+ + +AD G+A + L I +N VGT +MAPE++ + +
Sbjct: 145 IKAANVLLSEHGEVKLADFGVAGQ----LTDTQIKRNTFVGTPFWMAPEVIKQ----SAY 196
Query: 227 ESFKRADIYSVGLVYWEIAR 246
+S +ADI+S+G+ E+AR
Sbjct: 197 DS--KADIWSLGITAIELAR 214
>gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]
Length = 443
Score = 62.0 bits (149), Expect = 7e-10
Identities = 45/140 (32%), Positives = 71/140 (50%), Gaps = 18/140 (12%)
Query: 107 TQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRD 166
T+LW++ EY GS D L + + + I GL +LH E HRD
Sbjct: 105 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE--------KKIHRD 156
Query: 167 IKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIF 226
IK+ N+L+ + +AD G+A + L I +N VGT +MAPE++ + +
Sbjct: 157 IKAANVLLSEHGEVKLADFGVAGQ----LTDTQIKRNTFVGTPFWMAPEVIKQ----SAY 208
Query: 227 ESFKRADIYSVGLVYWEIAR 246
+S +ADI+S+G+ E+AR
Sbjct: 209 DS--KADIWSLGITAIELAR 226
>gi|4885489 v-mos Moloney murine sarcoma viral oncogene homolog
[Homo sapiens]
Length = 346
Score = 60.5 bits (145), Expect = 2e-09
Identities = 50/184 (27%), Positives = 82/184 (44%), Gaps = 32/184 (17%)
Query: 136 IKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSIL 195
+K +L + +GL LH + +I H D+K NIL+ + + C I+D G + K + +L
Sbjct: 179 LKYSLDVVNGLLFLHSQ--------SIVHLDLKPANILISEQDVCKISDFGCSEKLEDLL 230
Query: 196 NTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEI-ARRCSVGGIV 254
P P GT + APE+L +ADIYS + W++ ++ G
Sbjct: 231 -CFQTPSYPLGGTYTHRAPELLKGE------GVTPKADIYSFAITLWQMTTKQAPYSG-- 281
Query: 255 EEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAA 314
E Q Y +V D +R + F S+P Q +G +++ CW + A
Sbjct: 282 -ERQHILYAVVAYD-----LRPSLSAAVFEDSLPGQ--------RLGDVIQRCWRPSAAQ 327
Query: 315 RLTA 318
R +A
Sbjct: 328 RPSA 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.134 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,792,861
Number of Sequences: 37866
Number of extensions: 542941
Number of successful extensions: 2180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 469
Number of HSP's that attempted gapping in prelim test: 1479
Number of HSP's gapped (non-prelim): 725
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.