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Search of human proteins with 158508572
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|158508572 nuclear receptor subfamily 3, group C, member 2
[Homo sapiens]
(984 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 1987 0.0
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 471 e-132
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 471 e-132
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 471 e-132
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 471 e-132
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 471 e-132
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof... 466 e-131
gi|110611914 progesterone receptor [Homo sapiens] 443 e-124
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 420 e-117
gi|58535455 androgen receptor isoform 2 [Homo sapiens] 394 e-109
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 394 e-109
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 169 1e-41
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 169 1e-41
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 169 1e-41
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 169 1e-41
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 165 2e-40
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 162 1e-39
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 162 1e-39
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 162 1e-39
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 162 1e-39
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 162 2e-39
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 162 2e-39
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 162 2e-39
gi|238550159 estrogen-related receptor beta [Homo sapiens] 157 6e-38
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho... 124 4e-28
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho... 124 6e-28
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 122 1e-27
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso... 120 6e-27
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 120 6e-27
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 120 6e-27
>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
sapiens]
Length = 984
Score = 1987 bits (5147), Expect = 0.0
Identities = 984/984 (100%), Positives = 984/984 (100%)
Query: 1 METKGYHSLPEGLDMERRWGQVSQAVERSSLGPTERTDENNYMEIVNVSCVSGAIPNNST 60
METKGYHSLPEGLDMERRWGQVSQAVERSSLGPTERTDENNYMEIVNVSCVSGAIPNNST
Sbjct: 1 METKGYHSLPEGLDMERRWGQVSQAVERSSLGPTERTDENNYMEIVNVSCVSGAIPNNST 60
Query: 61 QGSSKEKQELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYE 120
QGSSKEKQELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYE
Sbjct: 61 QGSSKEKQELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYE 120
Query: 121 QQNQQGSMSPAKIYQNVEQLVKFYKGNGHRPSTLSCVNTPLRSFMSDSGSSVNGGVMRAV 180
QQNQQGSMSPAKIYQNVEQLVKFYKGNGHRPSTLSCVNTPLRSFMSDSGSSVNGGVMRAV
Sbjct: 121 QQNQQGSMSPAKIYQNVEQLVKFYKGNGHRPSTLSCVNTPLRSFMSDSGSSVNGGVMRAV 180
Query: 181 VKSPIMCHEKSPSVCSPLNMTSSVCSPAGINSVSSTTASFGSFPVHSPITQGTPLTCSPN 240
VKSPIMCHEKSPSVCSPLNMTSSVCSPAGINSVSSTTASFGSFPVHSPITQGTPLTCSPN
Sbjct: 181 VKSPIMCHEKSPSVCSPLNMTSSVCSPAGINSVSSTTASFGSFPVHSPITQGTPLTCSPN 240
Query: 241 VENRGSRSHSPAHASNVGSPLSSPLSSMKSSISSPPSHCSVKSPVSSPNNVTLRSSVSSP 300
VENRGSRSHSPAHASNVGSPLSSPLSSMKSSISSPPSHCSVKSPVSSPNNVTLRSSVSSP
Sbjct: 241 VENRGSRSHSPAHASNVGSPLSSPLSSMKSSISSPPSHCSVKSPVSSPNNVTLRSSVSSP 300
Query: 301 ANINNSRCSVSSPSNTNNRSTLSSPAASTVGSICSPVNNAFSYTASGTSAGSSTLRDVVP 360
ANINNSRCSVSSPSNTNNRSTLSSPAASTVGSICSPVNNAFSYTASGTSAGSSTLRDVVP
Sbjct: 301 ANINNSRCSVSSPSNTNNRSTLSSPAASTVGSICSPVNNAFSYTASGTSAGSSTLRDVVP 360
Query: 361 SPDTQEKGAQEVPFPKTEEVESAISNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINSD 420
SPDTQEKGAQEVPFPKTEEVESAISNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINSD
Sbjct: 361 SPDTQEKGAQEVPFPKTEEVESAISNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINSD 420
Query: 421 SSFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGF 480
SSFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGF
Sbjct: 421 SSFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGF 480
Query: 481 DGNCEGSGFPVGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSAR 540
DGNCEGSGFPVGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSAR
Sbjct: 481 DGNCEGSGFPVGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSAR 540
Query: 541 DQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPS 600
DQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPS
Sbjct: 541 DQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPS 600
Query: 601 KICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRL 660
KICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRL
Sbjct: 601 KICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRL 660
Query: 661 QKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVN 720
QKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVN
Sbjct: 661 QKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVN 720
Query: 721 TALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQV 780
TALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQV
Sbjct: 721 TALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQV 780
Query: 781 VKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKM 840
VKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKM
Sbjct: 781 VKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKM 840
Query: 841 HQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYI 900
HQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYI
Sbjct: 841 HQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYI 900
Query: 901 KELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAML 960
KELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAML
Sbjct: 901 KELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAML 960
Query: 961 VEIISDQLPKVESGNAKPLYFHRK 984
VEIISDQLPKVESGNAKPLYFHRK
Sbjct: 961 VEIISDQLPKVESGNAKPLYFHRK 984
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 471 bits (1212), Expect = e-132
Identities = 255/518 (49%), Positives = 332/518 (64%), Gaps = 55/518 (10%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCI 646
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEGQHNYLCAGRNDCI
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI 464
Query: 647 IDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEE 706
IDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------- 515
Query: 707 GTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLL 766
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ ++
Sbjct: 516 GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIM 560
Query: 767 STLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQF 826
+TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 TTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANL 620
Query: 827 LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL 886
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDGL
Sbjct: 621 LCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL 680
Query: 887 KSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTF 946
KSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH++V +LL +CF TF
Sbjct: 681 KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTF 740
Query: 947 RESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
+ + +EFP ML EII++Q+PK +GN K L FH+K
Sbjct: 741 LDK-TMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 777
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 471 bits (1212), Expect = e-132
Identities = 255/518 (49%), Positives = 332/518 (64%), Gaps = 55/518 (10%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCI 646
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEGQHNYLCAGRNDCI
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI 464
Query: 647 IDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEE 706
IDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------- 515
Query: 707 GTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLL 766
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ ++
Sbjct: 516 GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIM 560
Query: 767 STLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQF 826
+TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 TTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANL 620
Query: 827 LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL 886
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDGL
Sbjct: 621 LCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL 680
Query: 887 KSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTF 946
KSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH++V +LL +CF TF
Sbjct: 681 KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTF 740
Query: 947 RESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
+ + +EFP ML EII++Q+PK +GN K L FH+K
Sbjct: 741 LDK-TMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 777
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 471 bits (1212), Expect = e-132
Identities = 255/518 (49%), Positives = 332/518 (64%), Gaps = 55/518 (10%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCI 646
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEGQHNYLCAGRNDCI
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI 464
Query: 647 IDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEE 706
IDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------- 515
Query: 707 GTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLL 766
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ ++
Sbjct: 516 GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIM 560
Query: 767 STLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQF 826
+TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 TTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANL 620
Query: 827 LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL 886
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDGL
Sbjct: 621 LCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL 680
Query: 887 KSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTF 946
KSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH++V +LL +CF TF
Sbjct: 681 KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTF 740
Query: 947 RESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
+ + +EFP ML EII++Q+PK +GN K L FH+K
Sbjct: 741 LDK-TMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 777
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 471 bits (1212), Expect = e-132
Identities = 255/518 (49%), Positives = 332/518 (64%), Gaps = 55/518 (10%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCI 646
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEGQHNYLCAGRNDCI
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI 464
Query: 647 IDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEE 706
IDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------- 515
Query: 707 GTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLL 766
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ ++
Sbjct: 516 GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIM 560
Query: 767 STLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQF 826
+TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 TTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANL 620
Query: 827 LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL 886
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDGL
Sbjct: 621 LCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL 680
Query: 887 KSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTF 946
KSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH++V +LL +CF TF
Sbjct: 681 KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTF 740
Query: 947 RESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
+ + +EFP ML EII++Q+PK +GN K L FH+K
Sbjct: 741 LDK-TMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 777
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 471 bits (1212), Expect = e-132
Identities = 255/518 (49%), Positives = 332/518 (64%), Gaps = 55/518 (10%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCI 646
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEGQHNYLCAGRNDCI
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI 464
Query: 647 IDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEE 706
IDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------- 515
Query: 707 GTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLL 766
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ ++
Sbjct: 516 GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIM 560
Query: 767 STLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQF 826
+TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 TTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANL 620
Query: 827 LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL 886
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDGL
Sbjct: 621 LCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL 680
Query: 887 KSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTF 946
KSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH++V +LL +CF TF
Sbjct: 681 KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTF 740
Query: 947 RESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
+ + +EFP ML EII++Q+PK +GN K L FH+K
Sbjct: 741 LDK-TMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 777
>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
gamma [Homo sapiens]
Length = 778
Score = 466 bits (1200), Expect = e-131
Identities = 255/519 (49%), Positives = 332/519 (63%), Gaps = 56/519 (10%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEG-QHNYLCAGRNDC 645
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEG QHNYLCAGRNDC
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDC 464
Query: 646 IIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPE 705
IIDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------ 516
Query: 706 EGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENL 765
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ +
Sbjct: 517 -GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRI 560
Query: 766 LSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQ 825
++TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 MTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSAN 620
Query: 826 FLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDG 885
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDG
Sbjct: 621 LLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDG 680
Query: 886 LKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYT 945
LKSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH++V +LL +CF T
Sbjct: 681 LKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQT 740
Query: 946 FRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
F + + +EFP ML EII++Q+PK +GN K L FH+K
Sbjct: 741 FLDK-TMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 778
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 443 bits (1139), Expect = e-124
Identities = 223/411 (54%), Positives = 289/411 (70%), Gaps = 18/411 (4%)
Query: 575 PVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQ 634
P L Y+ + +S S S P KICL+CGDEASGCHYGV+TCGSCKVFFKRA+EGQ
Sbjct: 540 PYLNYLRPDSEASQSPQYSF-ESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQ 598
Query: 635 HNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHE-EQPQQQQ 693
HNYLCAGRNDCI+DKIRRKNCPACRL+KC QAGM LG RK KK K++ + + Q
Sbjct: 599 HNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQ 658
Query: 694 PPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAG 753
P P Q+ + T+ P + L+P L + +L +IEP+++YAG
Sbjct: 659 PVGVPNESQALSQRFTF-----SPGQDIQLIPPL-----------INLLMSIEPDVIYAG 702
Query: 754 YDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFA 813
+D++KPDT+ +LL++LN+L +Q++ VVKW+K LPGF+NL ++DQITLIQYSWM L F
Sbjct: 703 HDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFG 762
Query: 814 LSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMK 873
L WRSYKH + Q LYFAPDL+ NE++M +S+ Y LC M QI +FV+LQ++ EE+ MK
Sbjct: 763 LGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMK 822
Query: 874 VLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHD 933
VLLLL+TIP +GL+SQ FEEMR++YI+EL K + S QRFYQLTKLLD++HD
Sbjct: 823 VLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHD 882
Query: 934 LVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 984
LV L +C TF +S AL VEFP M+ E+I+ QLPK+ +G KPL FH+K
Sbjct: 883 LVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK 933
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 420 bits (1080), Expect = e-117
Identities = 231/469 (49%), Positives = 297/469 (63%), Gaps = 54/469 (11%)
Query: 492 GIKQEPDDGSYYPEASIPSSAIVG-----------VNSGGQSFHYRIGAQGTISLSRSAR 540
G+ ++ G+ Y +AS P + I+G SGGQ +HY + T SLS+
Sbjct: 290 GVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMN---TASLSQQQD 346
Query: 541 DQSFQHLSSFPPVNTLVESW---KSHGD--LSSRRSDGYPVLEYIPENVSSSTLR----- 590
+ ++ PP+ E+W + GD L+S + +P SS ++R
Sbjct: 347 QKPIFNV--IPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSS 404
Query: 591 ----SVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCI 646
S + + P K+CLVC DEASGCHYGV+TCGSCKVFFKRAVEGQHNYLCAGRNDCI
Sbjct: 405 PPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI 464
Query: 647 IDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEE 706
IDKIRRKNCPACR +KCLQAGMNL ARK+KK K+KGI + Q P
Sbjct: 465 IDKIRRKNCPACRYRKCLQAGMNLEARKTKK--KIKGIQQATTGVSQETSENP------- 515
Query: 707 GTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLL 766
G I PA P LTP+ V +LE IEPE++YAGYDSS PD+ ++
Sbjct: 516 GNKTIVPATLPQ---------------LTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIM 560
Query: 767 STLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQF 826
+TLN L G+Q+I VKWAK +PGF+NL L+DQ+TL+QYSWM L +FAL WRSY+ +++
Sbjct: 561 TTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANL 620
Query: 827 LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL 886
L FAPDL+ NE++M MY+ C+ M +S + RLQ+++EEY MK LLLLS++PKDGL
Sbjct: 621 LCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL 680
Query: 887 KSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLV 935
KSQ F+E+R YIKEL K + K NS Q+WQRFYQLTKLLDSMH+ V
Sbjct: 681 KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENV 729
>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
Length = 388
Score = 394 bits (1011), Expect = e-109
Identities = 203/388 (52%), Positives = 256/388 (65%), Gaps = 29/388 (7%)
Query: 599 PSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 658
P K CL+CGDEASGCHYG +TCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+C
Sbjct: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
Query: 659 RLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPS 718
RL+KC +AGM LGARK KKLG LK E + SP E TT
Sbjct: 84 RLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTT---------SPTEETT--------- 125
Query: 719 VNTALVPQLSTISRA----LTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAG 774
Q T+S P + VLE IEP +V AG+D+++PD+ LLS+LN L
Sbjct: 126 -------QKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGE 178
Query: 775 KQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLV 834
+Q++ VVKWAK LPGF+NL ++DQ+ +IQYSWM L FA+ WRS+ + NS+ LYFAPDLV
Sbjct: 179 RQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV 238
Query: 835 FNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEE 894
FNE +MH+S MY C M +S +F LQ+T +E+ MK LLL S IP DGLK+Q F+E
Sbjct: 239 FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDE 298
Query: 895 MRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKV 954
+R NYIKEL +++ N +RFYQLTKLLDS+ + +L +F F +SH + V
Sbjct: 299 LRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSV 358
Query: 955 EFPAMLVEIISDQLPKVESGNAKPLYFH 982
+FP M+ EIIS Q+PK+ SG KP+YFH
Sbjct: 359 DFPEMMAEIISVQVPKILSGKVKPIYFH 386
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 394 bits (1011), Expect = e-109
Identities = 203/388 (52%), Positives = 256/388 (65%), Gaps = 29/388 (7%)
Query: 599 PSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 658
P K CL+CGDEASGCHYG +TCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+C
Sbjct: 556 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 615
Query: 659 RLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPS 718
RL+KC +AGM LGARK KKLG LK E + SP E TT
Sbjct: 616 RLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTT---------SPTEETT--------- 657
Query: 719 VNTALVPQLSTISRA----LTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAG 774
Q T+S P + VLE IEP +V AG+D+++PD+ LLS+LN L
Sbjct: 658 -------QKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGE 710
Query: 775 KQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLV 834
+Q++ VVKWAK LPGF+NL ++DQ+ +IQYSWM L FA+ WRS+ + NS+ LYFAPDLV
Sbjct: 711 RQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV 770
Query: 835 FNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEE 894
FNE +MH+S MY C M +S +F LQ+T +E+ MK LLL S IP DGLK+Q F+E
Sbjct: 771 FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDE 830
Query: 895 MRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKV 954
+R NYIKEL +++ N +RFYQLTKLLDS+ + +L +F F +SH + V
Sbjct: 831 LRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSV 890
Query: 955 EFPAMLVEIISDQLPKVESGNAKPLYFH 982
+FP M+ EIIS Q+PK+ SG KP+YFH
Sbjct: 891 DFPEMMAEIISVQVPKILSGKVKPIYFH 918
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 169 bits (428), Expect = 1e-41
Identities = 109/375 (29%), Positives = 188/375 (50%), Gaps = 31/375 (8%)
Query: 585 SSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRND 644
S++ S++ S++ ++ C VC D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
Query: 645 CIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSP 704
C IDK RRK+C ACRL+KC + GM G + + G H+ Q +
Sbjct: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ-------------RDD 273
Query: 705 EEGTTYIAPAKE-------PSVNTALVPQLSTISRALTPSP-VMVLENIEPEIVYAGYDS 756
EG + A + PS + ++++ +LT V L + EP I+Y+ YD
Sbjct: 274 GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDP 333
Query: 757 SKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSW 816
++P + +++ L LA ++++ ++ WAK +PGF +L L DQ+ L++ +W+ + L W
Sbjct: 334 TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVW 393
Query: 817 RSYKHTNSQFLYFAPDLVFNEEK-MHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVL 875
RS +H L FAP+L+ + + M E+ + S +F + L EE+ +K +
Sbjct: 394 RSMEHPGK--LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI 451
Query: 876 LLLSTIPKDGLKSQAAFEEMRTNYIKELRK-------MVTKCPNNSGQSWQRFYQLTKLL 928
+LL++ L S E + + + L K ++ K Q QR QL +L
Sbjct: 452 ILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 929 DSMHDLVSDLLEFCF 943
+ + + +E +
Sbjct: 512 SHIRHMSNKGMEHLY 526
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 169 bits (428), Expect = 1e-41
Identities = 109/375 (29%), Positives = 188/375 (50%), Gaps = 31/375 (8%)
Query: 585 SSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRND 644
S++ S++ S++ ++ C VC D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
Query: 645 CIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSP 704
C IDK RRK+C ACRL+KC + GM G + + G H+ Q +
Sbjct: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ-------------RDD 273
Query: 705 EEGTTYIAPAKE-------PSVNTALVPQLSTISRALTPSP-VMVLENIEPEIVYAGYDS 756
EG + A + PS + ++++ +LT V L + EP I+Y+ YD
Sbjct: 274 GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDP 333
Query: 757 SKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSW 816
++P + +++ L LA ++++ ++ WAK +PGF +L L DQ+ L++ +W+ + L W
Sbjct: 334 TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVW 393
Query: 817 RSYKHTNSQFLYFAPDLVFNEEK-MHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVL 875
RS +H L FAP+L+ + + M E+ + S +F + L EE+ +K +
Sbjct: 394 RSMEHPGK--LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI 451
Query: 876 LLLSTIPKDGLKSQAAFEEMRTNYIKELRK-------MVTKCPNNSGQSWQRFYQLTKLL 928
+LL++ L S E + + + L K ++ K Q QR QL +L
Sbjct: 452 ILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 929 DSMHDLVSDLLEFCF 943
+ + + +E +
Sbjct: 512 SHIRHMSNKGMEHLY 526
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 169 bits (428), Expect = 1e-41
Identities = 109/375 (29%), Positives = 188/375 (50%), Gaps = 31/375 (8%)
Query: 585 SSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRND 644
S++ S++ S++ ++ C VC D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
Query: 645 CIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSP 704
C IDK RRK+C ACRL+KC + GM G + + G H+ Q +
Sbjct: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ-------------RDD 273
Query: 705 EEGTTYIAPAKE-------PSVNTALVPQLSTISRALTPSP-VMVLENIEPEIVYAGYDS 756
EG + A + PS + ++++ +LT V L + EP I+Y+ YD
Sbjct: 274 GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDP 333
Query: 757 SKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSW 816
++P + +++ L LA ++++ ++ WAK +PGF +L L DQ+ L++ +W+ + L W
Sbjct: 334 TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVW 393
Query: 817 RSYKHTNSQFLYFAPDLVFNEEK-MHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVL 875
RS +H L FAP+L+ + + M E+ + S +F + L EE+ +K +
Sbjct: 394 RSMEHPGK--LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI 451
Query: 876 LLLSTIPKDGLKSQAAFEEMRTNYIKELRK-------MVTKCPNNSGQSWQRFYQLTKLL 928
+LL++ L S E + + + L K ++ K Q QR QL +L
Sbjct: 452 ILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 929 DSMHDLVSDLLEFCF 943
+ + + +E +
Sbjct: 512 SHIRHMSNKGMEHLY 526
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 169 bits (428), Expect = 1e-41
Identities = 109/375 (29%), Positives = 188/375 (50%), Gaps = 31/375 (8%)
Query: 585 SSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRND 644
S++ S++ S++ ++ C VC D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
Query: 645 CIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSP 704
C IDK RRK+C ACRL+KC + GM G + + G H+ Q +
Sbjct: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ-------------RDD 273
Query: 705 EEGTTYIAPAKE-------PSVNTALVPQLSTISRALTPSP-VMVLENIEPEIVYAGYDS 756
EG + A + PS + ++++ +LT V L + EP I+Y+ YD
Sbjct: 274 GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDP 333
Query: 757 SKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSW 816
++P + +++ L LA ++++ ++ WAK +PGF +L L DQ+ L++ +W+ + L W
Sbjct: 334 TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVW 393
Query: 817 RSYKHTNSQFLYFAPDLVFNEEK-MHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVL 875
RS +H L FAP+L+ + + M E+ + S +F + L EE+ +K +
Sbjct: 394 RSMEHPGK--LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI 451
Query: 876 LLLSTIPKDGLKSQAAFEEMRTNYIKELRK-------MVTKCPNNSGQSWQRFYQLTKLL 928
+LL++ L S E + + + L K ++ K Q QR QL +L
Sbjct: 452 ILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 929 DSMHDLVSDLLEFCF 943
+ + + +E +
Sbjct: 512 SHIRHMSNKGMEHLY 526
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 165 bits (418), Expect = 2e-40
Identities = 101/287 (35%), Positives = 153/287 (53%), Gaps = 23/287 (8%)
Query: 596 SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 655
SS P ++CLVCGD ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C
Sbjct: 72 SSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKAC 131
Query: 656 PACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIA--P 713
ACR KCL+ GM ++ +L +++G ++ ++ + P P P P G +A P
Sbjct: 132 QACRFTKCLRVGM---LKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFP-AGPLAVAGGP 187
Query: 714 AKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLA 773
K + ALV L +EPE +YA D + PD ++TL L
Sbjct: 188 RKTAAPVNALVSHLLV---------------VEPEKLYAMPDPAGPDGHLPAVATLCDLF 232
Query: 774 GKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDL 833
++++ + WAK +PGF +L L DQ++++Q WM + ++ RS + L FA DL
Sbjct: 233 DREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDL 290
Query: 834 VFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLST 880
V +EE + + EL + Q+ + L+L EEY ++K L L ++
Sbjct: 291 VLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANS 337
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 162 bits (411), Expect = 1e-39
Identities = 109/376 (28%), Positives = 178/376 (47%), Gaps = 40/376 (10%)
Query: 505 EASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHG 564
E S P+S VN H+ G S S S+ Q+ PP+ G
Sbjct: 19 EPSSPASLTDSVN------HHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSG 72
Query: 565 DLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCK 624
+ D + P+ L S+ P ++CLVCGD ASG HYGV +C +CK
Sbjct: 73 PVRKLYDDCSSTIVEDPQTKCEYMLNSM------PKRLCLVCGDIASGYHYGVASCEACK 126
Query: 625 VFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGI 684
FFKR ++G Y C N+C I K RRK+C ACR KCL+ GM ++ +L +++G
Sbjct: 127 AFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGM---LKEGVRLDRVRGG 183
Query: 685 HEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLEN 744
++ ++ SP + PAK+ P +S L
Sbjct: 184 RQKYKRRID------AENSPYLNPQLVQPAKK--------PYNKIVSHLLV--------- 220
Query: 745 IEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQY 804
EPE +YA D + PD+ L+TL LA ++++ ++ WAK +PGF L L DQ++L+Q
Sbjct: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
Query: 805 SWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQL 864
+WM + + +RS + L +A D + +E++ + + +L + Q+ ++ ++L
Sbjct: 281 AWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKL 338
Query: 865 TFEEYTIMKVLLLLST 880
EE+ +K + L ++
Sbjct: 339 EKEEFVTLKAIALANS 354
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 162 bits (411), Expect = 1e-39
Identities = 109/376 (28%), Positives = 178/376 (47%), Gaps = 40/376 (10%)
Query: 505 EASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHG 564
E S P+S VN H+ G S S S+ Q+ PP+ G
Sbjct: 19 EPSSPASLTDSVN------HHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSG 72
Query: 565 DLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCK 624
+ D + P+ L S+ P ++CLVCGD ASG HYGV +C +CK
Sbjct: 73 PVRKLYDDCSSTIVEDPQTKCEYMLNSM------PKRLCLVCGDIASGYHYGVASCEACK 126
Query: 625 VFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGI 684
FFKR ++G Y C N+C I K RRK+C ACR KCL+ GM ++ +L +++G
Sbjct: 127 AFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGM---LKEGVRLDRVRGG 183
Query: 685 HEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLEN 744
++ ++ SP + PAK+ P +S L
Sbjct: 184 RQKYKRRID------AENSPYLNPQLVQPAKK--------PYNKIVSHLLV--------- 220
Query: 745 IEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQY 804
EPE +YA D + PD+ L+TL LA ++++ ++ WAK +PGF L L DQ++L+Q
Sbjct: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
Query: 805 SWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQL 864
+WM + + +RS + L +A D + +E++ + + +L + Q+ ++ ++L
Sbjct: 281 AWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKL 338
Query: 865 TFEEYTIMKVLLLLST 880
EE+ +K + L ++
Sbjct: 339 EKEEFVTLKAIALANS 354
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 162 bits (411), Expect = 1e-39
Identities = 109/376 (28%), Positives = 178/376 (47%), Gaps = 40/376 (10%)
Query: 505 EASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHG 564
E S P+S VN H+ G S S S+ Q+ PP+ G
Sbjct: 42 EPSSPASLTDSVN------HHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSG 95
Query: 565 DLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCK 624
+ D + P+ L S+ P ++CLVCGD ASG HYGV +C +CK
Sbjct: 96 PVRKLYDDCSSTIVEDPQTKCEYMLNSM------PKRLCLVCGDIASGYHYGVASCEACK 149
Query: 625 VFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGI 684
FFKR ++G Y C N+C I K RRK+C ACR KCL+ GM ++ +L +++G
Sbjct: 150 AFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGM---LKEGVRLDRVRGG 206
Query: 685 HEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLEN 744
++ ++ SP + PAK+ P +S L
Sbjct: 207 RQKYKRRID------AENSPYLNPQLVQPAKK--------PYNKIVSHLLV--------- 243
Query: 745 IEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQY 804
EPE +YA D + PD+ L+TL LA ++++ ++ WAK +PGF L L DQ++L+Q
Sbjct: 244 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 303
Query: 805 SWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQL 864
+WM + + +RS + L +A D + +E++ + + +L + Q+ ++ ++L
Sbjct: 304 AWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKL 361
Query: 865 TFEEYTIMKVLLLLST 880
EE+ +K + L ++
Sbjct: 362 EKEEFVTLKAIALANS 377
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 162 bits (411), Expect = 1e-39
Identities = 109/376 (28%), Positives = 178/376 (47%), Gaps = 40/376 (10%)
Query: 505 EASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHG 564
E S P+S VN H+ G S S S+ Q+ PP+ G
Sbjct: 19 EPSSPASLTDSVN------HHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSG 72
Query: 565 DLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCK 624
+ D + P+ L S+ P ++CLVCGD ASG HYGV +C +CK
Sbjct: 73 PVRKLYDDCSSTIVEDPQTKCEYMLNSM------PKRLCLVCGDIASGYHYGVASCEACK 126
Query: 625 VFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGI 684
FFKR ++G Y C N+C I K RRK+C ACR KCL+ GM ++ +L +++G
Sbjct: 127 AFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGM---LKEGVRLDRVRGG 183
Query: 685 HEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLEN 744
++ ++ SP + PAK+ P +S L
Sbjct: 184 RQKYKRRID------AENSPYLNPQLVQPAKK--------PYNKIVSHLLV--------- 220
Query: 745 IEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQY 804
EPE +YA D + PD+ L+TL LA ++++ ++ WAK +PGF L L DQ++L+Q
Sbjct: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
Query: 805 SWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQL 864
+WM + + +RS + L +A D + +E++ + + +L + Q+ ++ ++L
Sbjct: 281 AWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKL 338
Query: 865 TFEEYTIMKVLLLLST 880
EE+ +K + L ++
Sbjct: 339 EKEEFVTLKAIALANS 354
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 162 bits (409), Expect = 2e-39
Identities = 103/307 (33%), Positives = 156/307 (50%), Gaps = 24/307 (7%)
Query: 578 EYIPENVSSSTLRSVSTG--SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQH 635
E + VS + S TG S R + C VC D ASG HYGV +C CK FFKR+++G +
Sbjct: 122 ETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN 181
Query: 636 NYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGM-NLGARKSKKLGKLKGIHEEQPQQQQP 694
+Y+C N C IDK RRK+C ACRL+KC + GM G+R+ + +L +Q
Sbjct: 182 DYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHC 241
Query: 695 PPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGY 754
G + P V L+ LS LT +LE P ++ +
Sbjct: 242 -----------AGKAKRSGGHAPRVRELLLDALSPEQLVLT-----LLEAEPPHVLIS-- 283
Query: 755 DSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFAL 814
S P T +++ +L +LA K+++ ++ WAK +PGF L L DQ+ L++ WM + L
Sbjct: 284 RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL 343
Query: 815 SWRSYKHTNSQFLYFAPDLVFN-EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMK 873
WRS H L FAPDLV + +E + E+ + + +F L+L +EY +K
Sbjct: 344 MWRSIDHPGK--LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVK 401
Query: 874 VLLLLST 880
++LL++
Sbjct: 402 AMILLNS 408
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 162 bits (409), Expect = 2e-39
Identities = 103/307 (33%), Positives = 156/307 (50%), Gaps = 24/307 (7%)
Query: 578 EYIPENVSSSTLRSVSTG--SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQH 635
E + VS + S TG S R + C VC D ASG HYGV +C CK FFKR+++G +
Sbjct: 122 ETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN 181
Query: 636 NYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGM-NLGARKSKKLGKLKGIHEEQPQQQQP 694
+Y+C N C IDK RRK+C ACRL+KC + GM G+R+ + +L +Q
Sbjct: 182 DYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHC 241
Query: 695 PPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGY 754
G + P V L+ LS LT +LE P ++ +
Sbjct: 242 -----------AGKAKRSGGHAPRVRELLLDALSPEQLVLT-----LLEAEPPHVLIS-- 283
Query: 755 DSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFAL 814
S P T +++ +L +LA K+++ ++ WAK +PGF L L DQ+ L++ WM + L
Sbjct: 284 RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL 343
Query: 815 SWRSYKHTNSQFLYFAPDLVFN-EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMK 873
WRS H L FAPDLV + +E + E+ + + +F L+L +EY +K
Sbjct: 344 MWRSIDHPGK--LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVK 401
Query: 874 VLLLLST 880
++LL++
Sbjct: 402 AMILLNS 408
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 162 bits (409), Expect = 2e-39
Identities = 103/307 (33%), Positives = 156/307 (50%), Gaps = 24/307 (7%)
Query: 578 EYIPENVSSSTLRSVSTG--SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQH 635
E + VS + S TG S R + C VC D ASG HYGV +C CK FFKR+++G +
Sbjct: 122 ETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN 181
Query: 636 NYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGM-NLGARKSKKLGKLKGIHEEQPQQQQP 694
+Y+C N C IDK RRK+C ACRL+KC + GM G+R+ + +L +Q
Sbjct: 182 DYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHC 241
Query: 695 PPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGY 754
G + P V L+ LS LT +LE P ++ +
Sbjct: 242 -----------AGKAKRSGGHAPRVRELLLDALSPEQLVLT-----LLEAEPPHVLIS-- 283
Query: 755 DSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFAL 814
S P T +++ +L +LA K+++ ++ WAK +PGF L L DQ+ L++ WM + L
Sbjct: 284 RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGL 343
Query: 815 SWRSYKHTNSQFLYFAPDLVFN-EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMK 873
WRS H L FAPDLV + +E + E+ + + +F L+L +EY +K
Sbjct: 344 MWRSIDHPGK--LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVK 401
Query: 874 VLLLLST 880
++LL++
Sbjct: 402 AMILLNS 408
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 157 bits (396), Expect = 6e-38
Identities = 90/282 (31%), Positives = 148/282 (52%), Gaps = 28/282 (9%)
Query: 599 PSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 658
P ++CLVCGD ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK+C AC
Sbjct: 99 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 158
Query: 659 RLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPS 718
R KCL+ GM ++ +L +++G ++ ++ SP PAK+P
Sbjct: 159 RFMKCLKVGM---LKEGVRLDRVRGGRQKYKRRLD------SESSPYLSLQISPPAKKPL 209
Query: 719 VNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMI 778
V L EP+ +YA P+ L+TL LA ++++
Sbjct: 210 TKI-----------------VSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELV 252
Query: 779 QVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEE 838
++ WAK +PGF +L L DQ++L+Q +WM + + +RS + + L +A D + +EE
Sbjct: 253 VIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LVYAEDYIMDEE 310
Query: 839 KMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLST 880
+ + EL + + Q+ ++ +L++ EE+ +K L L ++
Sbjct: 311 HSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANS 352
>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
sapiens]
Length = 410
Score = 124 bits (311), Expect = 4e-28
Identities = 114/373 (30%), Positives = 169/373 (45%), Gaps = 42/373 (11%)
Query: 594 TGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLC-AGRNDCIIDKIRR 652
TG S PS C VCGD +SG HYG+ C C FFKR+V + Y C G C +DK R
Sbjct: 39 TGVS-PSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHR 97
Query: 653 KNCPACRLQKCLQAGMNLGARKSKK---------LGKLKGIHEEQPQQQQPPPPPPPPQS 703
C ACRL+KCLQAGMN A ++++ L ++ E +P + PP P +S
Sbjct: 98 NQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRP-ESLVAPPAPAGRS 156
Query: 704 PEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENI-----EPEIVYAGYDSSK 758
P G T ++ A+ ++ + L T P ENI +PE + Y SS
Sbjct: 157 P-RGPTPMSAAR--ALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSS 213
Query: 759 PDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSF-ALSWR 817
P +++ T RL + VKWAK LP F +LP DQ+ L++ +W L A+ W
Sbjct: 214 PCGLDSIHETSARL----LFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQW- 268
Query: 818 SYKHTNSQFLYFAPDLVFNEEKMHQSAMYEL------CQGMHQISLQFVRLQLTFEEYTI 871
S L P L E A L + + + +F L + E+
Sbjct: 269 ------SLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFAC 322
Query: 872 MKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSM 931
MK L+L + GLK E ++ + + + +K + S RF +L LL S+
Sbjct: 323 MKALVLFKPETR-GLKDPEHVEALQ-DQSQVMLSQHSKAHHPSQP--VRFGKLLLLLPSL 378
Query: 932 HDLVSDLLEFCFY 944
+ ++ +E F+
Sbjct: 379 RFITAERIELLFF 391
>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
sapiens]
Length = 367
Score = 124 bits (310), Expect = 6e-28
Identities = 83/228 (36%), Positives = 115/228 (50%), Gaps = 24/228 (10%)
Query: 594 TGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLC-AGRNDCIIDKIRR 652
TG S PS C VCGD +SG HYG+ C C FFKR+V + Y C G C +DK R
Sbjct: 39 TGVS-PSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHR 97
Query: 653 KNCPACRLQKCLQAGMNLGARKSKK---------LGKLKGIHEEQPQQQQPPPPPPPPQS 703
C ACRL+KCLQAGMN A ++++ L ++ E +P + PP P +S
Sbjct: 98 NQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRP-ESLVAPPAPAGRS 156
Query: 704 PEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENI-----EPEIVYAGYDSSK 758
P G T ++ A+ ++ + L T P ENI +PE + Y SS
Sbjct: 157 P-RGPTPMSAAR--ALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSS 213
Query: 759 PDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSW 806
P +++ T RL + VKWAK LP F +LP DQ+ L++ +W
Sbjct: 214 PCGLDSIHETSARL----LFMAVKWAKNLPVFSSLPFRDQVILLEEAW 257
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 122 bits (307), Expect = 1e-27
Identities = 109/406 (26%), Positives = 175/406 (43%), Gaps = 44/406 (10%)
Query: 571 SDGYPVLE--YIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFK 628
S G+P L+ + + + + S GS +C VCGD A+ HYGV TC CK FFK
Sbjct: 229 SMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFK 288
Query: 629 RAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQ 688
R V+ Y+C +C +DK RR C CR QKCL GM ++ L +G +
Sbjct: 289 RTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSK 348
Query: 689 PQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRA-LTPSPVMVLENIEP 747
P+ Q P PP PP V +S + RA + +P M +
Sbjct: 349 PKSPQEPSPPSPP----------------------VSLISALVRAHVDSNPAMTSLDYSR 386
Query: 748 EIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWM 807
Y S DT +++ + L G I + WA+ +PGF +LP DQ L + +++
Sbjct: 387 FQANPDYQMSGDDT-QHIQQFYDLLTGSMEI-IRGWAEKIPGFADLPKADQDLLFESAFL 444
Query: 808 CLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFE 867
L L++RS L F +V + + + E + + S + +
Sbjct: 445 ELFVLRLAYRSNPVEGK--LIFCNGVVLHRLQCVR-GFGEWIDSIVEFSSNLQNMNIDIS 501
Query: 868 EYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKL 927
++ + L +++ + GLK EE++ + L+ VT NN G + + L+KL
Sbjct: 502 AFSCIAALAMVT--ERHGLKEPKRVEELQNKIVNCLKDHVTF--NNGGLNRPNY--LSKL 555
Query: 928 LDSMHDLVSDLLEFCFYTFRESHALKVEF----PAMLVEIISDQLP 969
L + +L C + LK+E PA++ ++ D LP
Sbjct: 556 LGKL----PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLP 597
>gi|194294519 nuclear receptor subfamily 1, group H, member 3
isoform c [Homo sapiens]
Length = 402
Score = 120 bits (301), Expect = 6e-27
Identities = 80/310 (25%), Positives = 142/310 (45%), Gaps = 11/310 (3%)
Query: 600 SKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACR 659
+++C VCGD+ASG HY V++C CK FF+R+V +Y+C C +D R+ C CR
Sbjct: 50 NELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECR 109
Query: 660 LQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSV 719
L+KC QAGM S++ +LK + ++ +Q PP SP + ++P + +
Sbjct: 110 LRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMI 169
Query: 720 NTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQ 779
+ Q R+ + + + P D + + + LA + +
Sbjct: 170 EKLVAAQQQCNRRSFSDRLRVTPWPMAP-------DPHSREARQQRFAHFTELAIVSVQE 222
Query: 780 VVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEK 839
+V +AK LPGF L EDQI L++ S + L + S+ + F D +N E
Sbjct: 223 IVDFAKQLPGFLQLSREDQIALLKTS--AIEVMLLETSRRYNPGSESITFLKDFSYNRED 280
Query: 840 MHQSAM-YELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTN 898
++ + E + + S LQL E+ ++ + + S + ++ Q E ++
Sbjct: 281 FAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSA-DRPNVQDQLQVERLQHT 339
Query: 899 YIKELRKMVT 908
Y++ L V+
Sbjct: 340 YVEALHAYVS 349
>gi|194294517 nuclear receptor subfamily 1, group H, member 3
isoform a [Homo sapiens]
Length = 447
Score = 120 bits (301), Expect = 6e-27
Identities = 80/310 (25%), Positives = 142/310 (45%), Gaps = 11/310 (3%)
Query: 600 SKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACR 659
+++C VCGD+ASG HY V++C CK FF+R+V +Y+C C +D R+ C CR
Sbjct: 95 NELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECR 154
Query: 660 LQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSV 719
L+KC QAGM S++ +LK + ++ +Q PP SP + ++P + +
Sbjct: 155 LRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMI 214
Query: 720 NTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQ 779
+ Q R+ + + + P D + + + LA + +
Sbjct: 215 EKLVAAQQQCNRRSFSDRLRVTPWPMAP-------DPHSREARQQRFAHFTELAIVSVQE 267
Query: 780 VVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEK 839
+V +AK LPGF L EDQI L++ S + L + S+ + F D +N E
Sbjct: 268 IVDFAKQLPGFLQLSREDQIALLKTS--AIEVMLLETSRRYNPGSESITFLKDFSYNRED 325
Query: 840 MHQSAM-YELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTN 898
++ + E + + S LQL E+ ++ + + S + ++ Q E ++
Sbjct: 326 FAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSA-DRPNVQDQLQVERLQHT 384
Query: 899 YIKELRKMVT 908
Y++ L V+
Sbjct: 385 YVEALHAYVS 394
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 120 bits (301), Expect = 6e-27
Identities = 103/353 (29%), Positives = 148/353 (41%), Gaps = 53/353 (15%)
Query: 574 YPVLEYIPENVSSSTLRSVSTGSSRPSK-------ICLVCGDEASGCHYGVVTCGSCKVF 626
+P L P +SS L + S PS+ C VCGD A+ HYGV TC CK F
Sbjct: 267 FPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGF 326
Query: 627 FKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGM--------NLGARKSKKL 678
FKR V+ Y+C +C +DK RR C CR QKCL GM +L R+ +
Sbjct: 327 FKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLP 386
Query: 679 GKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSP 738
K K +++P Q PP PP + ++ + RALT S
Sbjct: 387 SKPKSPLQQEPSQPSPPSPP-------------------------ICMMNALVRALTDST 421
Query: 739 VMVLENIEPEIVYAGYDSSKPDT-AENLLSTLNRLAGKQMIQVVK-WAKVLPGFKNLPLE 796
L+ Y D + T AE++ N L I V + WA+ +PGF +LP E
Sbjct: 422 PRDLDYSR----YCPTDQAAAGTDAEHVQQFYNLLTAS--IDVSRSWAEKIPGFTDLPKE 475
Query: 797 DQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQIS 856
DQ LI+ +++ L LS RS +T F LV + + + E + S
Sbjct: 476 DQTLLIESAFLELFVLRLSIRS--NTAEDKFVFCNGLVLHRLQCLR-GFGEWLDSIKDFS 532
Query: 857 LQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTK 909
L L L + + L +++ + GLK EE+ L+ +K
Sbjct: 533 LNLQSLNLDIQALACLSALSMIT--ERHGLKEPKRVEELCNKITSSLKDHQSK 583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,311,337
Number of Sequences: 37866
Number of extensions: 2238860
Number of successful extensions: 22067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 375
Number of HSP's that attempted gapping in prelim test: 16109
Number of HSP's gapped (non-prelim): 4341
length of query: 984
length of database: 18,247,518
effective HSP length: 112
effective length of query: 872
effective length of database: 14,006,526
effective search space: 12213690672
effective search space used: 12213690672
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.