Search of human proteins with 157738647

Search of human proteins with 157738647

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157738647 plexin A4 isoform 3 [Homo sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157738647 plexin A4 isoform 3 [Homo sapiens]                       997   0.0  
gi|157738643 plexin A4 isoform 2 [Homo sapiens]                       929   0.0  
gi|157738645 plexin A4 isoform 1 [Homo sapiens]                       927   0.0  
gi|113722116 plexin A2 [Homo sapiens]                                 520   e-147
gi|49355818 plexin A1 [Homo sapiens]                                  471   e-133
gi|59710104 plexin A3 [Homo sapiens]                                  462   e-130
gi|149363636 plexin B2 [Homo sapiens]                                 156   4e-38
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]     132   7e-31
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]    132   7e-31
gi|194272180 plexin B1 [Homo sapiens]                                 119   8e-27
gi|40254442 plexin B1 [Homo sapiens]                                  119   8e-27
gi|253795481 plexin B3 isoform 2 [Homo sapiens]                       112   8e-25
gi|29336063 plexin B3 isoform 1 [Homo sapiens]                        112   8e-25
gi|157694524 plexin D1 [Homo sapiens]                                  88   2e-17
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s...    76   8e-14
gi|39777610 semaphorin 4B precursor [Homo sapiens]                     50   6e-06
gi|39777608 semaphorin 4B precursor [Homo sapiens]                     50   6e-06
gi|19718780 semaphorin 6B precursor [Homo sapiens]                     36   0.091
gi|21361914 semaphorin B [Homo sapiens]                                34   0.35 
gi|5174673 semaphorin 3A precursor [Homo sapiens]                      33   0.45 
gi|9910362 semaphorin sem2 [Homo sapiens]                              32   1.3  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    30   6.5  
gi|7657015 hypothetical protein LOC51493 [Homo sapiens]                29   8.5  

>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
          Length = 492

 Score =  997 bits (2577), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
           MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60

Query: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
           GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120

Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
           DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180

Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
           DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240

Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
           DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300

Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
           ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360

Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
           KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420

Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGTSLCPTLELQTGPRSHRATV 480
           GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGTSLCPTLELQTGPRSHRATV
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGTSLCPTLELQTGPRSHRATV 480

Query: 481 TLELLFSSCSSN 492
           TLELLFSSCSSN
Sbjct: 481 TLELLFSSCSSN 492


>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
          Length = 522

 Score =  929 bits (2401), Expect = 0.0
 Identities = 459/461 (99%), Positives = 459/461 (99%)

Query: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
           MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60

Query: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
           GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120

Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
           DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180

Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
           DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240

Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
           DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300

Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
           ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360

Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
           KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420

Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGT 461
           GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK  GT
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGT 461


>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
          Length = 1894

 Score =  927 bits (2396), Expect = 0.0
 Identities = 457/458 (99%), Positives = 458/458 (100%)

Query: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
           MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60

Query: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
           GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120

Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
           DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180

Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
           DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240

Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
           DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300

Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
           ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360

Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
           KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420

Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
           GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK+
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKI 458


>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score =  520 bits (1338), Expect = e-147
 Identities = 253/432 (58%), Positives = 323/432 (74%), Gaps = 6/432 (1%)

Query: 31  APLSQKQRSFVTFRGEPAEG-FNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPD 89
           AP +     F TF  E  +  FNHL V + TG +Y+GA+NR+YKL+ +L + V H+TGP+
Sbjct: 29  APPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPE 88

Query: 90  EDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKL 149
           EDN  CYPP IVQ C+E LT TNNVNK+L+IDY ENRL+ACGSLYQG+CKLLRL+DLF L
Sbjct: 89  EDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFIL 148

Query: 150 GEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSE 209
            EP HKKEHYLS VN++G+++GVIV     D KLFI TAVDGK +YFPT+SSRKL ++ E
Sbjct: 149 VEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPE 208

Query: 210 ADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPG- 268
           +  M  Y  H +FV+S+IKIPSDT  ++  FDI+Y+YGF+SG FVYFLT+QPE  +P G 
Sbjct: 209 SSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE--TPEGV 266

Query: 269 --STTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTL 326
             ++  +  YTS++VRLCK+D  F+SYV +P GC R+GVEYRLLQAAYL+K G  L +  
Sbjct: 267 AINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAF 326

Query: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386
            +   DD+LF +FSKGQK+     D+SALC F ++ IN +IKERLQSCY+GEG L+L WL
Sbjct: 327 NITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWL 386

Query: 387 KVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLA 446
             KD+ C+ A + IDDNFCGLD+N PLG S  V G+ ++T  RDRMTSV +YVY  +S+ 
Sbjct: 387 LGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVV 446

Query: 447 FVGTKSGKLKKM 458
           FVGTKSGKLKK+
Sbjct: 447 FVGTKSGKLKKI 458


>gi|49355818 plexin A1 [Homo sapiens]
          Length = 1873

 Score =  471 bits (1212), Expect = e-133
 Identities = 228/411 (55%), Positives = 297/411 (72%), Gaps = 2/411 (0%)

Query: 50  GFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLT 109
           G  HLVV E+TG +Y+GAVNRIYKLS +L +L  H TGP EDN KCYPP  VQ+C   L 
Sbjct: 27  GLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86

Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
           +T+NVNK+LL+DY  NRL+ACGS  QGIC+ LRL+DLFKLGEP+H+KEHYLS V E+GS+
Sbjct: 87  STDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSM 146

Query: 170 FGVIVSY--SNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMI 227
            GV+++        KLF+ T +DGK EYFPT+SSR+L  N E   MF +V+ DEFV+S +
Sbjct: 147 AGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQL 206

Query: 228 KIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKED 287
           KIPSDT +  P FDIYYVY F S  FVY+LTLQ +          E  +TSK+VRLC +D
Sbjct: 207 KIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD 266

Query: 288 TAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKM 347
             F SYVE PIGCE++GVEYRL+Q AYLS+ G  L   LG+  D+D+LFTVF++GQK ++
Sbjct: 267 PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRV 326

Query: 348 KSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGL 407
           K   ESALC+F L+ I ++IKER+QSCYRGEG L L WL  K++ C ++ L IDD+FCG 
Sbjct: 327 KPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQ 386

Query: 408 DMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
           D N PLG +  + G P+F +  D +T+V AY Y+  ++ F GT+SG+++K+
Sbjct: 387 DFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKI 437


>gi|59710104 plexin A3 [Homo sapiens]
          Length = 1871

 Score =  462 bits (1190), Expect = e-130
 Identities = 224/435 (51%), Positives = 299/435 (68%)

Query: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
           HL V   TG +++GAVNR++KL+ +L  L  H TGP EDN +CYPP  ++ C   L   +
Sbjct: 35  HLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVD 94

Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGV 172
           N+NK+LLIDY   RL+ACGS++QGIC+ LRL+DLFKLGEP+H+KEHYLSG  E  S+ GV
Sbjct: 95  NINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGV 154

Query: 173 IVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSD 232
           IV       KLF+ TAVDGK EYFPT+SSRKL  + ++  MF+ V+ DEFV+S IKIPSD
Sbjct: 155 IVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214

Query: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNS 292
           T ++ P FDIYY+YGF S +FVYFLTLQ +       T  E+ +TSK+VR+C  D+ F S
Sbjct: 215 TLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYS 274

Query: 293 YVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDE 352
           YVE PIGC   GVEYRL+Q+A+L+K G +L + LGV  D+D+LFT+FS+GQK +     +
Sbjct: 275 YVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ 334

Query: 353 SALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAP 412
           + LC+F L  IN  I+ R+QSCYRGEGTL L WL  K++PC +  + I+ NFCGL +N P
Sbjct: 335 TILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQP 394

Query: 413 LGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGTSLCPTLELQTG 472
           LG   ++ G+P+  +  D M SV AY Y+ HS+ F+GT+SG LKK+           +T 
Sbjct: 395 LGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETV 454

Query: 473 PRSHRATVTLELLFS 487
           P    + +  +LLFS
Sbjct: 455 PVVDGSPILRDLLFS 469


>gi|149363636 plexin B2 [Homo sapiens]
          Length = 1838

 Score =  156 bits (395), Expect = 4e-38
 Identities = 122/441 (27%), Positives = 201/441 (45%), Gaps = 37/441 (8%)

Query: 24  TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVT 83
           TLL    A  S + R    FR E  +  NHL VDE +G +YLGAVN +Y+L + L++   
Sbjct: 9   TLLGLLGAGASLRPRKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66

Query: 84  HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRL 143
             TGP  DN KC PP     C+E    T+NVN++LL+D    RL+ CGSL++GIC L  L
Sbjct: 67  VATGPALDNKKCTPPIEASQCHE-AEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125

Query: 144 ED--LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISS 201
            +  L    E    ++ +++  +E  +  G++ S     D++      +G  +    +S+
Sbjct: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVST 185

Query: 202 RKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQP 261
           R L +    +   AY  H  + A  +   +  F          V  F  G +V+F+  Q 
Sbjct: 186 RLLDRTDSREAFEAYTDHATYKAGYLSTNTQQF----------VAAFEDGPYVFFVFNQQ 235

Query: 262 EMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAV 321
           +       T         L R+C+ED  + SY+E+ + C    +        + +  G  
Sbjct: 236 DKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGTC 279

Query: 322 LGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTL 381
           L  ++       +L+ VFS+    +      + LC+F L +++ +++    +CY G    
Sbjct: 280 LAASVAAPGSGRVLYAVFSRDS--RSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREA 337

Query: 382 DLAWLKV--KDIPCSSALLTIDDNF-CGLD-MNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
              + K    DI C         +F CG + +  PLG  D +RG  V       +T+V  
Sbjct: 338 RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397

Query: 438 YVYKNHSLAFVGTKSGKLKKM 458
               NH++AF+GT  G++ K+
Sbjct: 398 AAENNHTVAFLGTSDGRILKV 418


>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
          Length = 1390

 Score =  132 bits (332), Expect = 7e-31
 Identities = 98/343 (28%), Positives = 173/343 (50%), Gaps = 70/343 (20%)

Query: 62  HIYLGAVNRIYKLSS-DLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTT-----NNVN 115
           HI+LGA N IY L+  DL+ +  ++TGP  ++P C+P    Q C+     +     +N+N
Sbjct: 61  HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNIN 117

Query: 116 KMLLID-YKENRLIACGSLYQGICKL------------LRLEDLF--KLGEPYHKKEHYL 160
             L++D Y +++LI+CGS+ +G C+               +  +F  ++ EP    +  +
Sbjct: 118 MALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVV 177

Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFP-----TISSRKLTKNSEADGMFA 215
           S +        V+ S  +     F+   ++    YFP     +IS R+L +  +    F 
Sbjct: 178 SALGAK-----VLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDG---FM 227

Query: 216 YVFHDEFVASMIKIPSDTFTIIPDF----DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
           ++    ++            ++P+F     I YV+ F S NF+YFLT+Q E       T 
Sbjct: 228 FLTDQSYI-----------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRE-------TL 269

Query: 272 KEQVYTSKLVRLCKEDTAFNSYVEVPIGC-------ERSGVE--YRLLQAAYLSKAGAVL 322
             Q + ++++R C  ++  +SY+E+P+ C       +RS  +  + +LQAAY+SK GA L
Sbjct: 270 DAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQL 329

Query: 323 GRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIND 365
            R +G   +DD+LF VF++ +    + +D SA+C F +K +ND
Sbjct: 330 ARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVND 372


>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
          Length = 1408

 Score =  132 bits (332), Expect = 7e-31
 Identities = 98/343 (28%), Positives = 173/343 (50%), Gaps = 70/343 (20%)

Query: 62  HIYLGAVNRIYKLSS-DLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTT-----NNVN 115
           HI+LGA N IY L+  DL+ +  ++TGP  ++P C+P    Q C+     +     +N+N
Sbjct: 61  HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNIN 117

Query: 116 KMLLID-YKENRLIACGSLYQGICKL------------LRLEDLF--KLGEPYHKKEHYL 160
             L++D Y +++LI+CGS+ +G C+               +  +F  ++ EP    +  +
Sbjct: 118 MALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVV 177

Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFP-----TISSRKLTKNSEADGMFA 215
           S +        V+ S  +     F+   ++    YFP     +IS R+L +  +    F 
Sbjct: 178 SALGAK-----VLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDG---FM 227

Query: 216 YVFHDEFVASMIKIPSDTFTIIPDF----DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
           ++    ++            ++P+F     I YV+ F S NF+YFLT+Q E       T 
Sbjct: 228 FLTDQSYI-----------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRE-------TL 269

Query: 272 KEQVYTSKLVRLCKEDTAFNSYVEVPIGC-------ERSGVE--YRLLQAAYLSKAGAVL 322
             Q + ++++R C  ++  +SY+E+P+ C       +RS  +  + +LQAAY+SK GA L
Sbjct: 270 DAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQL 329

Query: 323 GRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIND 365
            R +G   +DD+LF VF++ +    + +D SA+C F +K +ND
Sbjct: 330 ARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVND 372


>gi|194272180 plexin B1 [Homo sapiens]
          Length = 2135

 Score =  119 bits (297), Expect = 8e-27
 Identities = 114/445 (25%), Positives = 203/445 (45%), Gaps = 56/445 (12%)

Query: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95

Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170
           N N++LL+      L+ CGS++QG+C+  RL  L + L  P    +  Y++  + + S  
Sbjct: 96  NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153

Query: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210

Query: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
                   + ++  ++V  F+ G   YFL L+ ++        + + + + + R+C  D 
Sbjct: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256

Query: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS        
Sbjct: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306

Query: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396
           +       +   SALC F L +++        +CY    R E   ++A+++  D+    A
Sbjct: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365

Query: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425

Query: 453 GKLKKM---PGTSLCP--TLELQTG 472
           G+L ++   PG+   P  T  +Q G
Sbjct: 426 GQLHRVYLGPGSDGHPYSTQSIQQG 450


>gi|40254442 plexin B1 [Homo sapiens]
          Length = 2135

 Score =  119 bits (297), Expect = 8e-27
 Identities = 114/445 (25%), Positives = 203/445 (45%), Gaps = 56/445 (12%)

Query: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95

Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170
           N N++LL+      L+ CGS++QG+C+  RL  L + L  P    +  Y++  + + S  
Sbjct: 96  NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153

Query: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210

Query: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
                   + ++  ++V  F+ G   YFL L+ ++        + + + + + R+C  D 
Sbjct: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256

Query: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS        
Sbjct: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306

Query: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396
           +       +   SALC F L +++        +CY    R E   ++A+++  D+    A
Sbjct: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365

Query: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425

Query: 453 GKLKKM---PGTSLCP--TLELQTG 472
           G+L ++   PG+   P  T  +Q G
Sbjct: 426 GQLHRVYLGPGSDGHPYSTQSIQQG 450


>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
          Length = 1932

 Score =  112 bits (280), Expect = 8e-25
 Identities = 119/455 (26%), Positives = 199/455 (43%), Gaps = 85/455 (18%)

Query: 25  LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
           LL+  P PL+   R        P    NHL +    G +Y+GAVNR+++LS +L++    
Sbjct: 56  LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 110

Query: 85  ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
            TGP  D+P C P R    C +    T+N N++LL+  +   L+ACG + QG+C+  RL 
Sbjct: 111 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 169

Query: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
           D    L++  +P      +++      +  G++V      D L +A  + GK     P +
Sbjct: 170 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 226

Query: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
           + R+L  +    ++G+   V  D                  D++  YV  F+     YF 
Sbjct: 227 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 269

Query: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
                 V        +  Y S + R+C  DT   SYVEVP+ C+  G    L+QAA+L+ 
Sbjct: 270 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 318

Query: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
            G +LG              VF+ G +       ++ALC F + ++   +++  + CY  
Sbjct: 319 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 359

Query: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
             RG    + A ++      C +  L   +++ CG       +    PL V  +++ G P
Sbjct: 360 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 419

Query: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
           V        ++V A     H +AF+G   G+L K+
Sbjct: 420 V--------SAVAALQADGHMIAFLGDTQGQLYKV 446


>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
          Length = 1909

 Score =  112 bits (280), Expect = 8e-25
 Identities = 119/455 (26%), Positives = 199/455 (43%), Gaps = 85/455 (18%)

Query: 25  LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
           LL+  P PL+   R        P    NHL +    G +Y+GAVNR+++LS +L++    
Sbjct: 33  LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 87

Query: 85  ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
            TGP  D+P C P R    C +    T+N N++LL+  +   L+ACG + QG+C+  RL 
Sbjct: 88  VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 146

Query: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
           D    L++  +P      +++      +  G++V      D L +A  + GK     P +
Sbjct: 147 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 203

Query: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
           + R+L  +    ++G+   V  D                  D++  YV  F+     YF 
Sbjct: 204 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 246

Query: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
                 V        +  Y S + R+C  DT   SYVEVP+ C+  G    L+QAA+L+ 
Sbjct: 247 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 295

Query: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
            G +LG              VF+ G +       ++ALC F + ++   +++  + CY  
Sbjct: 296 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 336

Query: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
             RG    + A ++      C +  L   +++ CG       +    PL V  +++ G P
Sbjct: 337 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 396

Query: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
           V        ++V A     H +AF+G   G+L K+
Sbjct: 397 V--------SAVAALQADGHMIAFLGDTQGQLYKV 423


>gi|157694524 plexin D1 [Homo sapiens]
          Length = 1925

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 109/463 (23%), Positives = 178/463 (38%), Gaps = 81/463 (17%)

Query: 52  NHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPKCYPPRIVQ-TCNEPLT 109
           N+  +D   G +YL AVNR+Y+LS ++L +      GP  D+P C+ P++ Q +C  P  
Sbjct: 60  NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119

Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
            T+N NK+L +D  +  ++ CGS+YQG C+L R  ++  +   +         V    S+
Sbjct: 120 LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179

Query: 170 FGVIVSYSNLD--------------DKLFIATAVDGKPEYF---------------PTIS 200
             V  ++ N                 +L +     G    F               P I+
Sbjct: 180 LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239

Query: 201 SRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLT-- 258
            R L    +   +F +  +          PSD      D  +    G    + + F++  
Sbjct: 240 IRSLDTRGDLAKLFTFDLN----------PSD------DNILKIKQGAKEQHKLGFVSAF 283

Query: 259 LQPEMVSPPGSTT--------------KEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSG 304
           L P    PPG+ +              KE    S L R+C    A     ++     + G
Sbjct: 284 LHPS-DPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLG 342

Query: 305 VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIN 364
                LQ A  +  G +  R + V P  + LF VF + Q         +ALC F    + 
Sbjct: 343 -----LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVR 397

Query: 365 DRIKERLQSCYRGEGTLDLAWLKVKDI----PCSSALLTIDDNFCGLDMNA-----PLGV 415
             I+    +C+  E   D+  +    +    P     L I      LD  A     PL +
Sbjct: 398 AAIRAARTACF-VEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSI 456

Query: 416 SDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
              ++  PVF      +TSV      N++  F+GT +G+L K+
Sbjct: 457 LQPLKATPVFR--APGLTSVAVASVNNYTAVFLGTVNGRLLKI 497


>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
           sapiens]
          Length = 1400

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 90/348 (25%), Positives = 143/348 (41%), Gaps = 56/348 (16%)

Query: 57  DERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTC-------NEPLT 109
           D     +++   NR++ L  DLK + +  TGP  D P C      QTC       + P  
Sbjct: 64  DRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGD-PGC------QTCAACGPGPHGPPG 116

Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLED---LFKLGEP------YHKKEHYL 160
            T+   K+L++D     L++CGS  QG C L  LE       L  P      +H +    
Sbjct: 117 DTDT--KVLVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC 174

Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGK--PEYFP-TISSRKLTKNSEADGMFAYV 217
                S     V V         ++A+++D      + P ++S R+L   ++A G     
Sbjct: 175 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRL--KADASG----- 227

Query: 218 FHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYT 277
           F   FVA  + +P      +  + I YV+ F +G FVYFLT+QP  V     T       
Sbjct: 228 FAPGFVALSV-LPKH----LVSYSIEYVHSFHTGAFVYFLTVQPASV-----TDDPSALH 277

Query: 278 SKLVRLCKEDTAFNSYVEVPIGCE-----------RSGVEYRLLQAAYLSKAGAVLGRTL 326
           ++L RL   +     Y E+ + C              G  Y +L+ A+ +  GA L   L
Sbjct: 278 TRLARLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATEL 337

Query: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSC 374
            +    ++LF VF  G+         S +C F +  ++  I E ++ C
Sbjct: 338 SIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERC 385


>gi|39777610 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 86/379 (22%), Positives = 147/379 (38%), Gaps = 68/379 (17%)

Query: 11  LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNR 70
           LL  LL     +  L  R   PL  ++R F+ F  E    +  L++      +Y+GA   
Sbjct: 30  LLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREA 89

Query: 71  IYKLSSDLKVLVTHE-----TGPDEDNPKCYPPRIVQTCN----EPLTTTNNVNKMLLID 121
           ++ LSS+L  L   E      G D +          Q C+    +P     N  K+LL  
Sbjct: 90  LFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIKILL-P 140

Query: 122 YKENRLIACG-SLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNL- 179
              + L  CG + +  +C  + +E+ F L     +K + L    +    F      + L 
Sbjct: 141 LSGSHLFTCGTAAFSPMCTYINMEN-FTLAR--DEKGNVLLEDGKGRCPFDPNFKSTALV 197

Query: 180 -DDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIP 238
            D +L+  T V       P IS  +  + ++ +    ++    FVAS   IP    ++  
Sbjct: 198 VDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGSLQG 255

Query: 239 DFD-IYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA-------- 289
           D D IY+ +  +   F +F                E    S++ R+CK D          
Sbjct: 256 DDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVLQQR 299

Query: 290 FNSYVEVPIGCER--SGVEYRLLQAAYLSKAGAVLGRTLGVHPD---DDLLFTVFSKGQK 344
           + S+++  + C R   G  + +LQ  +          TL   P    D L + VF+    
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVF----------TLSPSPQDWRDTLFYGVFTSQWH 349

Query: 345 RKMKSLDESALCIFILKQI 363
           R   + + SA+C+F +K +
Sbjct: 350 R--GTTEGSAVCVFTMKDV 366


>gi|39777608 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 86/379 (22%), Positives = 147/379 (38%), Gaps = 68/379 (17%)

Query: 11  LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNR 70
           LL  LL     +  L  R   PL  ++R F+ F  E    +  L++      +Y+GA   
Sbjct: 30  LLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREA 89

Query: 71  IYKLSSDLKVLVTHE-----TGPDEDNPKCYPPRIVQTCN----EPLTTTNNVNKMLLID 121
           ++ LSS+L  L   E      G D +          Q C+    +P     N  K+LL  
Sbjct: 90  LFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIKILL-P 140

Query: 122 YKENRLIACG-SLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNL- 179
              + L  CG + +  +C  + +E+ F L     +K + L    +    F      + L 
Sbjct: 141 LSGSHLFTCGTAAFSPMCTYINMEN-FTLAR--DEKGNVLLEDGKGRCPFDPNFKSTALV 197

Query: 180 -DDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIP 238
            D +L+  T V       P IS  +  + ++ +    ++    FVAS   IP    ++  
Sbjct: 198 VDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGSLQG 255

Query: 239 DFD-IYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA-------- 289
           D D IY+ +  +   F +F                E    S++ R+CK D          
Sbjct: 256 DDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVLQQR 299

Query: 290 FNSYVEVPIGCER--SGVEYRLLQAAYLSKAGAVLGRTLGVHPD---DDLLFTVFSKGQK 344
           + S+++  + C R   G  + +LQ  +          TL   P    D L + VF+    
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVF----------TLSPSPQDWRDTLFYGVFTSQWH 349

Query: 345 RKMKSLDESALCIFILKQI 363
           R   + + SA+C+F +K +
Sbjct: 350 R--GTTEGSAVCVFTMKDV 366


>gi|19718780 semaphorin 6B precursor [Homo sapiens]
          Length = 888

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 92/395 (23%), Positives = 150/395 (37%), Gaps = 105/395 (26%)

Query: 11  LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTF----------RGEPAEGFNHLVVDE-- 58
           LL  LL++G G+  L   +P PLS   R ++            R  PAEG + L +    
Sbjct: 13  LLLLLLLLG-GAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71

Query: 59  ---RTGHIYLGAVNRIYKL------SSDLKVL--VTHETGPDEDNPKCYPPRIVQTCNEP 107
              RT  +++G  + +Y++      S++L+    +T  + P + N      +    C   
Sbjct: 72  RVNRT--LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECR-- 127

Query: 108 LTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRLEDLFKLGE--------PYHKKEH 158
               N V  +LL D  E+ L  CGS  +  +C    ++ L  +G+        PY  K  
Sbjct: 128 ----NFVKVLLLRD--ESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPK-- 179

Query: 159 YLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVF 218
                + + ++F         D  LF AT  D     F  I           D +     
Sbjct: 180 -----HANVALFS--------DGMLFTATVTD-----FLAI-----------DAVIYRSL 210

Query: 219 HDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTS 278
            D      +K  S  F      + Y+V+    G+ VYF   +  M         E+V  S
Sbjct: 211 GDRPTLRTVKHDSKWFK-----EPYFVHAVEWGSHVYFFFREIAMEF----NYLEKVVVS 261

Query: 279 KLVRLCKEDTA---------FNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLG-RTLGV 328
           ++ R+CK D           + S+++  + C   G  +      Y +   AV G  +LG 
Sbjct: 262 RVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH-----FYFNVLQAVTGVVSLGG 316

Query: 329 HPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQI 363
            P   ++  VFS        S+  SA+C F L Q+
Sbjct: 317 RP---VVLAVFS----TPSNSIPGSAVCAFDLTQV 344


>gi|21361914 semaphorin B [Homo sapiens]
          Length = 761

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 70/368 (19%), Positives = 140/368 (38%), Gaps = 80/368 (21%)

Query: 118 LLIDYKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSY 176
           +L+ Y    L  CG+  +   C  + L+D + L      ++  + G  +S        + 
Sbjct: 130 VLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPI---SEDKVMEGKGQSPFDPAHKHTA 186

Query: 177 SNLDDKLFIATA---VDGKPEYFPTISSRKLTKNSEADGMFAYVFHD-EFVASMIKIPSD 232
             +D  L+  T    +  +P    T+ S+ + K    D    ++ HD  FVA+   IPS 
Sbjct: 187 VLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKT---DNFLRWLHHDASFVAA---IPST 240

Query: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA--- 289
                    +Y+ +  ++  F +F                E+++TS++ R+CK D     
Sbjct: 241 QV-------VYFFFEETASEFDFF----------------ERLHTSRVARVCKNDVGGEK 277

Query: 290 -----FNSYVEVPIGCERSG-VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQ 343
                + ++++  + C + G + + +++ A L  A +         P    ++ VF+   
Sbjct: 278 LLQKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADS---------PTAPHIYAVFT--S 326

Query: 344 KRKMKSLDESALCIFILKQINDRIKERLQ---------SCYRGEGTLDLAWLKVKDIPCS 394
           + ++     SA+C F L  I    K + +         + YRG  T              
Sbjct: 327 QWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPSSD 386

Query: 395 SALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYK-----NHSLAFVG 449
            AL  + D+F          + + V G P+  +     T +     +     +H + ++G
Sbjct: 387 KALTFMKDHFL---------MDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLG 437

Query: 450 TKSGKLKK 457
           T +G L K
Sbjct: 438 TTTGSLHK 445


>gi|5174673 semaphorin 3A precursor [Homo sapiens]
          Length = 771

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 24/166 (14%)

Query: 36  KQRSFVTFRG-EPAEGFNHLVVDERTGHIYLGAVNRIYKLS----SDLKVLVTHETGPDE 90
           +  + +TF G   +  ++  ++DE    +Y+GA + I+        D + +V   +    
Sbjct: 41  ESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVNIKDFQKIVWPVSYTRR 100

Query: 91  DNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRL-----E 144
           D  K     I++ C        N  K+L   Y +  L ACG+  +  IC  + +     +
Sbjct: 101 DECKWAGKDILKEC-------ANFIKVLKA-YNQTHLYACGTGAFHPICTYIEIGHHPED 152

Query: 145 DLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVD 190
           ++FKL     +  H+ +G  +S     ++ +   +D +L+  TA D
Sbjct: 153 NIFKL-----ENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAAD 193


>gi|9910362 semaphorin sem2 [Homo sapiens]
          Length = 782

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 50/207 (24%), Positives = 80/207 (38%), Gaps = 36/207 (17%)

Query: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAP--------LSQKQRSFVTFRGEPAEGFN 52
           M    W    LL  LL+ G GSS        P        L    RS +    + +    
Sbjct: 1   MAPSAWAICWLLGGLLLHG-GSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLNLQ 59

Query: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPR------IVQTCNE 106
            + +DE    ++LG ++ +Y L  D       +  PD      +PP+       V+   +
Sbjct: 60  AMYLDEYRDRLFLGGLDALYSLRLD-------QAWPD-PREVLWPPQPGQREECVRKGRD 111

Query: 107 PLTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNE 165
           PLT   N  ++L   +    L+ACG+  +Q  C L+ +          H+ EH L    E
Sbjct: 112 PLTECANFVRVLQ-PHNRTHLLACGTGAFQPTCALITVG---------HRGEHVLH--LE 159

Query: 166 SGSVFGVIVSYSNLDDKLFIATAVDGK 192
            GSV        +   + F +T +DG+
Sbjct: 160 PGSVESGRGRCPHEPSRPFASTFIDGE 186


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 36   KQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKC 95
            +Q+   T +GE  E  + L   E T H+Y  + N + KL S+LK L    T       KC
Sbjct: 2275 QQKVCDTLQGENKELLSQL---EETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKC 2331


>gi|7657015 hypothetical protein LOC51493 [Homo sapiens]
          Length = 505

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 9/74 (12%)

Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRL---------CKEDTAFN 291
           D++  YGF+ GN   F    PE V  PG    +     +L+R           KE  A  
Sbjct: 87  DVHSGYGFAIGNMAAFDMNDPEAVVSPGGVGFDINCGVRLLRTNLDESDVQPVKEQLAQA 146

Query: 292 SYVEVPIGCERSGV 305
            +  +P+G    GV
Sbjct: 147 MFDHIPVGVGSKGV 160


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,924,990
Number of Sequences: 37866
Number of extensions: 838967
Number of successful extensions: 1649
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1594
Number of HSP's gapped (non-prelim): 28
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.