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Search of human proteins with 157738643
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157738643 plexin A4 isoform 2 [Homo sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 1063 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 932 0.0
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 929 0.0
gi|113722116 plexin A2 [Homo sapiens] 527 e-150
gi|49355818 plexin A1 [Homo sapiens] 471 e-133
gi|59710104 plexin A3 [Homo sapiens] 461 e-130
gi|149363636 plexin B2 [Homo sapiens] 157 2e-38
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 132 8e-31
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 132 8e-31
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 120 3e-27
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 120 3e-27
gi|194272180 plexin B1 [Homo sapiens] 119 5e-27
gi|40254442 plexin B1 [Homo sapiens] 119 5e-27
gi|157694524 plexin D1 [Homo sapiens] 88 2e-17
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 76 9e-14
gi|39777610 semaphorin 4B precursor [Homo sapiens] 55 2e-07
gi|39777608 semaphorin 4B precursor [Homo sapiens] 55 2e-07
gi|21361914 semaphorin B [Homo sapiens] 38 0.026
gi|19718780 semaphorin 6B precursor [Homo sapiens] 36 0.098
gi|5174673 semaphorin 3A precursor [Homo sapiens] 33 0.49
gi|9910362 semaphorin sem2 [Homo sapiens] 32 1.4
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens] 31 3.1
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 30 7.0
gi|7657015 hypothetical protein LOC51493 [Homo sapiens] 29 9.2
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 1063 bits (2749), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
Query: 61 GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61 GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPG 480
GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPG
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPG 480
Query: 481 ANIASQEQMLCVYLQCSSHKAISDQRVQPLLCCFLNVPGNSS 522
ANIASQEQMLCVYLQCSSHKAISDQRVQPLLCCFLNVPGNSS
Sbjct: 481 ANIASQEQMLCVYLQCSSHKAISDQRVQPLLCCFLNVPGNSS 522
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 932 bits (2409), Expect = 0.0
Identities = 461/469 (98%), Positives = 462/469 (98%)
Query: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
Query: 61 GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61 GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQ 469
GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK GP+G Q
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQ 469
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 929 bits (2401), Expect = 0.0
Identities = 459/461 (99%), Positives = 459/461 (99%)
Query: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
Query: 61 GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61 GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGT 461
GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK GT
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGT 461
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 527 bits (1358), Expect = e-150
Identities = 261/455 (57%), Positives = 333/455 (73%), Gaps = 9/455 (1%)
Query: 31 APLSQKQRSFVTFRGEPAEG-FNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPD 89
AP + F TF E + FNHL V + TG +Y+GA+NR+YKL+ +L + V H+TGP+
Sbjct: 29 APPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPE 88
Query: 90 EDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKL 149
EDN CYPP IVQ C+E LT TNNVNK+L+IDY ENRL+ACGSLYQG+CKLLRL+DLF L
Sbjct: 89 EDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFIL 148
Query: 150 GEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSE 209
EP HKKEHYLS VN++G+++GVIV D KLFI TAVDGK +YFPT+SSRKL ++ E
Sbjct: 149 VEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPE 208
Query: 210 ADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPG- 268
+ M Y H +FV+S+IKIPSDT ++ FDI+Y+YGF+SG FVYFLT+QPE +P G
Sbjct: 209 SSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE--TPEGV 266
Query: 269 --STTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTL 326
++ + YTS++VRLCK+D F+SYV +P GC R+GVEYRLLQAAYL+K G L +
Sbjct: 267 AINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAF 326
Query: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386
+ DD+LF +FSKGQK+ D+SALC F ++ IN +IKERLQSCY+GEG L+L WL
Sbjct: 327 NITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWL 386
Query: 387 KVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLA 446
KD+ C+ A + IDDNFCGLD+N PLG S V G+ ++T RDRMTSV +YVY +S+
Sbjct: 387 LGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVV 446
Query: 447 FVGTKSGKLKKSFGTG-PQGGITQEWIGV--EGDP 478
FVGTKSGKLKK G P GG+ E + V +G P
Sbjct: 447 FVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSP 481
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 471 bits (1211), Expect = e-133
Identities = 228/410 (55%), Positives = 296/410 (72%), Gaps = 2/410 (0%)
Query: 50 GFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLT 109
G HLVV E+TG +Y+GAVNRIYKLS +L +L H TGP EDN KCYPP VQ+C L
Sbjct: 27 GLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86
Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
+T+NVNK+LL+DY NRL+ACGS QGIC+ LRL+DLFKLGEP+H+KEHYLS V E+GS+
Sbjct: 87 STDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSM 146
Query: 170 FGVIVSY--SNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMI 227
GV+++ KLF+ T +DGK EYFPT+SSR+L N E MF +V+ DEFV+S +
Sbjct: 147 AGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQL 206
Query: 228 KIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKED 287
KIPSDT + P FDIYYVY F S FVY+LTLQ + E +TSK+VRLC +D
Sbjct: 207 KIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD 266
Query: 288 TAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKM 347
F SYVE PIGCE++GVEYRL+Q AYLS+ G L LG+ D+D+LFTVF++GQK ++
Sbjct: 267 PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRV 326
Query: 348 KSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGL 407
K ESALC+F L+ I ++IKER+QSCYRGEG L L WL K++ C ++ L IDD+FCG
Sbjct: 327 KPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQ 386
Query: 408 DMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK 457
D N PLG + + G P+F + D +T+V AY Y+ ++ F GT+SG+++K
Sbjct: 387 DFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRK 436
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 461 bits (1186), Expect = e-130
Identities = 224/427 (52%), Positives = 296/427 (69%), Gaps = 1/427 (0%)
Query: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
HL V TG +++GAVNR++KL+ +L L H TGP EDN +CYPP ++ C L +
Sbjct: 35 HLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVD 94
Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGV 172
N+NK+LLIDY RL+ACGS++QGIC+ LRL+DLFKLGEP+H+KEHYLSG E S+ GV
Sbjct: 95 NINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGV 154
Query: 173 IVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSD 232
IV KLF+ TAVDGK EYFPT+SSRKL + ++ MF+ V+ DEFV+S IKIPSD
Sbjct: 155 IVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214
Query: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNS 292
T ++ P FDIYY+YGF S +FVYFLTLQ + T E+ +TSK+VR+C D+ F S
Sbjct: 215 TLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYS 274
Query: 293 YVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDE 352
YVE PIGC GVEYRL+Q+A+L+K G +L + LGV D+D+LFT+FS+GQK + +
Sbjct: 275 YVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ 334
Query: 353 SALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAP 412
+ LC+F L IN I+ R+QSCYRGEGTL L WL K++PC + + I+ NFCGL +N P
Sbjct: 335 TILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQP 394
Query: 413 LGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWI 472
LG ++ G+P+ + D M SV AY Y+ HS+ F+GT+SG LKK G Q E +
Sbjct: 395 LGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETV 454
Query: 473 G-VEGDP 478
V+G P
Sbjct: 455 PVVDGSP 461
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 157 bits (397), Expect = 2e-38
Identities = 125/448 (27%), Positives = 204/448 (45%), Gaps = 38/448 (8%)
Query: 24 TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVT 83
TLL A S + R FR E + NHL VDE +G +YLGAVN +Y+L + L++
Sbjct: 9 TLLGLLGAGASLRPRKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66
Query: 84 HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRL 143
TGP DN KC PP C+E T+NVN++LL+D RL+ CGSL++GIC L L
Sbjct: 67 VATGPALDNKKCTPPIEASQCHE-AEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125
Query: 144 ED--LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISS 201
+ L E ++ +++ +E + G++ S D++ +G + +S+
Sbjct: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVST 185
Query: 202 RKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQP 261
R L + + AY H + A + + F V F G +V+F+ Q
Sbjct: 186 RLLDRTDSREAFEAYTDHATYKAGYLSTNTQQF----------VAAFEDGPYVFFVFNQQ 235
Query: 262 EMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAV 321
+ T L R+C+ED + SY+E+ + C + + + G
Sbjct: 236 DKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGTC 279
Query: 322 LGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTL 381
L ++ +L+ VFS+ + + LC+F L +++ +++ +CY G
Sbjct: 280 LAASVAAPGSGRVLYAVFSRDS--RSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREA 337
Query: 382 DLAWLKV--KDIPCSSALLTIDDNF-CGLD-MNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
+ K DI C +F CG + + PLG D +RG V +T+V
Sbjct: 338 RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397
Query: 438 YVYKNHSLAFVGTKSGKLKKSFGTGPQG 465
NH++AF+GT G++ K + T P G
Sbjct: 398 AAENNHTVAFLGTSDGRILKVYLT-PDG 424
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 132 bits (332), Expect = 8e-31
Identities = 98/343 (28%), Positives = 173/343 (50%), Gaps = 70/343 (20%)
Query: 62 HIYLGAVNRIYKLSS-DLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTT-----NNVN 115
HI+LGA N IY L+ DL+ + ++TGP ++P C+P Q C+ + +N+N
Sbjct: 61 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNIN 117
Query: 116 KMLLID-YKENRLIACGSLYQGICKL------------LRLEDLF--KLGEPYHKKEHYL 160
L++D Y +++LI+CGS+ +G C+ + +F ++ EP + +
Sbjct: 118 MALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVV 177
Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFP-----TISSRKLTKNSEADGMFA 215
S + V+ S + F+ ++ YFP +IS R+L + + F
Sbjct: 178 SALGAK-----VLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDG---FM 227
Query: 216 YVFHDEFVASMIKIPSDTFTIIPDF----DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
++ ++ ++P+F I YV+ F S NF+YFLT+Q E T
Sbjct: 228 FLTDQSYI-----------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRE-------TL 269
Query: 272 KEQVYTSKLVRLCKEDTAFNSYVEVPIGC-------ERSGVE--YRLLQAAYLSKAGAVL 322
Q + ++++R C ++ +SY+E+P+ C +RS + + +LQAAY+SK GA L
Sbjct: 270 DAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQL 329
Query: 323 GRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIND 365
R +G +DD+LF VF++ + + +D SA+C F +K +ND
Sbjct: 330 ARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVND 372
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 132 bits (332), Expect = 8e-31
Identities = 98/343 (28%), Positives = 173/343 (50%), Gaps = 70/343 (20%)
Query: 62 HIYLGAVNRIYKLSS-DLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTT-----NNVN 115
HI+LGA N IY L+ DL+ + ++TGP ++P C+P Q C+ + +N+N
Sbjct: 61 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNIN 117
Query: 116 KMLLID-YKENRLIACGSLYQGICKL------------LRLEDLF--KLGEPYHKKEHYL 160
L++D Y +++LI+CGS+ +G C+ + +F ++ EP + +
Sbjct: 118 MALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVV 177
Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFP-----TISSRKLTKNSEADGMFA 215
S + V+ S + F+ ++ YFP +IS R+L + + F
Sbjct: 178 SALGAK-----VLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDG---FM 227
Query: 216 YVFHDEFVASMIKIPSDTFTIIPDF----DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
++ ++ ++P+F I YV+ F S NF+YFLT+Q E T
Sbjct: 228 FLTDQSYI-----------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRE-------TL 269
Query: 272 KEQVYTSKLVRLCKEDTAFNSYVEVPIGC-------ERSGVE--YRLLQAAYLSKAGAVL 322
Q + ++++R C ++ +SY+E+P+ C +RS + + +LQAAY+SK GA L
Sbjct: 270 DAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQL 329
Query: 323 GRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIND 365
R +G +DD+LF VF++ + + +D SA+C F +K +ND
Sbjct: 330 ARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVND 372
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 120 bits (301), Expect = 3e-27
Identities = 128/481 (26%), Positives = 211/481 (43%), Gaps = 88/481 (18%)
Query: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 56 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 110
Query: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 111 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 169
Query: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
D L++ +P +++ + G++V D L +A + GK P +
Sbjct: 170 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 226
Query: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
+ R+L + ++G+ V D D++ YV F+ YF
Sbjct: 227 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 269
Query: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
V + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+
Sbjct: 270 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 318
Query: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
G +LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 319 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 359
Query: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
RG + A ++ C + L +++ CG + PL V +++ G P
Sbjct: 360 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 419
Query: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPGANI 483
V ++V A H +AF+G G+L K F G QG Q + + PPG+ I
Sbjct: 420 V--------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQG---QVYHSQQVGPPGSAI 468
Query: 484 A 484
+
Sbjct: 469 S 469
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 120 bits (301), Expect = 3e-27
Identities = 128/481 (26%), Positives = 211/481 (43%), Gaps = 88/481 (18%)
Query: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 33 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 87
Query: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 88 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 146
Query: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
D L++ +P +++ + G++V D L +A + GK P +
Sbjct: 147 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 203
Query: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
+ R+L + ++G+ V D D++ YV F+ YF
Sbjct: 204 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 246
Query: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
V + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+
Sbjct: 247 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 295
Query: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
G +LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 296 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 336
Query: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
RG + A ++ C + L +++ CG + PL V +++ G P
Sbjct: 337 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 396
Query: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPGANI 483
V ++V A H +AF+G G+L K F G QG Q + + PPG+ I
Sbjct: 397 V--------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQG---QVYHSQQVGPPGSAI 445
Query: 484 A 484
+
Sbjct: 446 S 446
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 119 bits (299), Expect = 5e-27
Identities = 111/434 (25%), Positives = 198/434 (45%), Gaps = 52/434 (11%)
Query: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
HL D +G +YLGA N +++LS L++ T TGP D+ C PP + C + TN
Sbjct: 37 HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95
Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170
N N++LL+ L+ CGS++QG+C+ RL L + L P + Y++ + + S
Sbjct: 96 NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
Query: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
G++ + LF+ G P I++R L D A+ + + ++ +
Sbjct: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210
Query: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
+ ++ ++V F+ G YFL L+ ++ + + + + + R+C D
Sbjct: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256
Query: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340
+ SYVE+P+ CE G Y L+QAA ++ + V ++LF FS
Sbjct: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306
Query: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396
+ + SALC F L +++ +CY R E ++A+++ D+ A
Sbjct: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
Query: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
L T+D CG D +P+ + P+ ++T+V + H++AF+G
Sbjct: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
Query: 453 GKLKKSF-GTGPQG 465
G+L + + G G G
Sbjct: 426 GQLHRVYLGPGSDG 439
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 119 bits (299), Expect = 5e-27
Identities = 111/434 (25%), Positives = 198/434 (45%), Gaps = 52/434 (11%)
Query: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
HL D +G +YLGA N +++LS L++ T TGP D+ C PP + C + TN
Sbjct: 37 HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95
Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170
N N++LL+ L+ CGS++QG+C+ RL L + L P + Y++ + + S
Sbjct: 96 NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
Query: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
G++ + LF+ G P I++R L D A+ + + ++ +
Sbjct: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210
Query: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
+ ++ ++V F+ G YFL L+ ++ + + + + + R+C D
Sbjct: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256
Query: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340
+ SYVE+P+ CE G Y L+QAA ++ + V ++LF FS
Sbjct: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306
Query: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396
+ + SALC F L +++ +CY R E ++A+++ D+ A
Sbjct: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
Query: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
L T+D CG D +P+ + P+ ++T+V + H++AF+G
Sbjct: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
Query: 453 GKLKKSF-GTGPQG 465
G+L + + G G G
Sbjct: 426 GQLHRVYLGPGSDG 439
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 87.8 bits (216), Expect = 2e-17
Identities = 109/462 (23%), Positives = 177/462 (38%), Gaps = 81/462 (17%)
Query: 52 NHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPKCYPPRIVQ-TCNEPLT 109
N+ +D G +YL AVNR+Y+LS ++L + GP D+P C+ P++ Q +C P
Sbjct: 60 NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119
Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
T+N NK+L +D + ++ CGS+YQG C+L R ++ + + V S+
Sbjct: 120 LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179
Query: 170 FGVIVSYSNLD--------------DKLFIATAVDGKPEYF---------------PTIS 200
V ++ N +L + G F P I+
Sbjct: 180 LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239
Query: 201 SRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLT-- 258
R L + +F + + PSD D + G + + F++
Sbjct: 240 IRSLDTRGDLAKLFTFDLN----------PSD------DNILKIKQGAKEQHKLGFVSAF 283
Query: 259 LQPEMVSPPGSTT--------------KEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSG 304
L P PPG+ + KE S L R+C A ++ + G
Sbjct: 284 LHPS-DPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLG 342
Query: 305 VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIN 364
LQ A + G + R + V P + LF VF + Q +ALC F +
Sbjct: 343 -----LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVR 397
Query: 365 DRIKERLQSCYRGEGTLDLAWLKVKDI----PCSSALLTIDDNFCGLDMNA-----PLGV 415
I+ +C+ E D+ + + P L I LD A PL +
Sbjct: 398 AAIRAARTACF-VEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSI 456
Query: 416 SDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK 457
++ PVF +TSV N++ F+GT +G+L K
Sbjct: 457 LQPLKATPVFR--APGLTSVAVASVNNYTAVFLGTVNGRLLK 496
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 75.9 bits (185), Expect = 9e-14
Identities = 90/348 (25%), Positives = 143/348 (41%), Gaps = 56/348 (16%)
Query: 57 DERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTC-------NEPLT 109
D +++ NR++ L DLK + + TGP D P C QTC + P
Sbjct: 64 DRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGD-PGC------QTCAACGPGPHGPPG 116
Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLED---LFKLGEP------YHKKEHYL 160
T+ K+L++D L++CGS QG C L LE L P +H +
Sbjct: 117 DTDT--KVLVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC 174
Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGK--PEYFP-TISSRKLTKNSEADGMFAYV 217
S V V ++A+++D + P ++S R+L ++A G
Sbjct: 175 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRL--KADASG----- 227
Query: 218 FHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYT 277
F FVA + +P + + I YV+ F +G FVYFLT+QP V T
Sbjct: 228 FAPGFVALSV-LPKH----LVSYSIEYVHSFHTGAFVYFLTVQPASV-----TDDPSALH 277
Query: 278 SKLVRLCKEDTAFNSYVEVPIGCE-----------RSGVEYRLLQAAYLSKAGAVLGRTL 326
++L RL + Y E+ + C G Y +L+ A+ + GA L L
Sbjct: 278 TRLARLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATEL 337
Query: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSC 374
+ ++LF VF G+ S +C F + ++ I E ++ C
Sbjct: 338 SIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERC 385
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 55.1 bits (131), Expect = 2e-07
Identities = 108/505 (21%), Positives = 190/505 (37%), Gaps = 91/505 (18%)
Query: 11 LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNR 70
LL LL + L R PL ++R F+ F E + L++ +Y+GA
Sbjct: 30 LLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREA 89
Query: 71 IYKLSSDLKVLVTHET-----GPDEDNPKCYPPRIVQTCN----EPLTTTNNVNKMLLID 121
++ LSS+L L E G D + Q C+ +P N K+LL
Sbjct: 90 LFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIKILL-P 140
Query: 122 YKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNL- 179
+ L CG+ + +C + +E+ F L +K + L + F + L
Sbjct: 141 LSGSHLFTCGTAAFSPMCTYINMEN-FTLARD--EKGNVLLEDGKGRCPFDPNFKSTALV 197
Query: 180 -DDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIP 238
D +L+ T V P IS + + ++ + ++ FVAS IP ++
Sbjct: 198 VDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGSLQG 255
Query: 239 DFD-IYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA-------- 289
D D IY+ + + F +F E S++ R+CK D
Sbjct: 256 DDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVLQQR 299
Query: 290 FNSYVEVPIGCER--SGVEYRLLQAAYLSKAGAVLGRTLGVHPDD---DLLFTVFSKGQK 344
+ S+++ + C R G + +LQ + TL P D L + VF+
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVF----------TLSPSPQDWRDTLFYGVFTSQWH 349
Query: 345 RKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD-IPCSSALLTIDDN 403
R + + SA+C+F +K + + Y+ W V +P I ++
Sbjct: 350 RG--TTEGSAVCVFTMKDV----QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNS 403
Query: 404 FCGLDMNAPLGVSD--------------MVRGIPVFTEDRDRMTSVIAY----VYKNHSL 445
+N+ L + D VR + + + R V + ++ + +
Sbjct: 404 ARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDV 463
Query: 446 AFVGTKSGKLKKSFGTGPQGGITQE 470
F+GT G+L K+ GP+ I +E
Sbjct: 464 LFLGTGDGRLHKAVSVGPRVHIIEE 488
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 55.1 bits (131), Expect = 2e-07
Identities = 108/505 (21%), Positives = 190/505 (37%), Gaps = 91/505 (18%)
Query: 11 LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNR 70
LL LL + L R PL ++R F+ F E + L++ +Y+GA
Sbjct: 30 LLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREA 89
Query: 71 IYKLSSDLKVLVTHET-----GPDEDNPKCYPPRIVQTCN----EPLTTTNNVNKMLLID 121
++ LSS+L L E G D + Q C+ +P N K+LL
Sbjct: 90 LFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIKILL-P 140
Query: 122 YKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNL- 179
+ L CG+ + +C + +E+ F L +K + L + F + L
Sbjct: 141 LSGSHLFTCGTAAFSPMCTYINMEN-FTLARD--EKGNVLLEDGKGRCPFDPNFKSTALV 197
Query: 180 -DDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIP 238
D +L+ T V P IS + + ++ + ++ FVAS IP ++
Sbjct: 198 VDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGSLQG 255
Query: 239 DFD-IYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA-------- 289
D D IY+ + + F +F E S++ R+CK D
Sbjct: 256 DDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVLQQR 299
Query: 290 FNSYVEVPIGCER--SGVEYRLLQAAYLSKAGAVLGRTLGVHPDD---DLLFTVFSKGQK 344
+ S+++ + C R G + +LQ + TL P D L + VF+
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVF----------TLSPSPQDWRDTLFYGVFTSQWH 349
Query: 345 RKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD-IPCSSALLTIDDN 403
R + + SA+C+F +K + + Y+ W V +P I ++
Sbjct: 350 RG--TTEGSAVCVFTMKDV----QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNS 403
Query: 404 FCGLDMNAPLGVSD--------------MVRGIPVFTEDRDRMTSVIAY----VYKNHSL 445
+N+ L + D VR + + + R V + ++ + +
Sbjct: 404 ARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDV 463
Query: 446 AFVGTKSGKLKKSFGTGPQGGITQE 470
F+GT G+L K+ GP+ I +E
Sbjct: 464 LFLGTGDGRLHKAVSVGPRVHIIEE 488
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 37.7 bits (86), Expect = 0.026
Identities = 75/389 (19%), Positives = 148/389 (38%), Gaps = 80/389 (20%)
Query: 118 LLIDYKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSY 176
+L+ Y L CG+ + C + L+D + L ++ + G +S +
Sbjct: 130 VLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPI---SEDKVMEGKGQSPFDPAHKHTA 186
Query: 177 SNLDDKLFIATA---VDGKPEYFPTISSRKLTKNSEADGMFAYVFHD-EFVASMIKIPSD 232
+D L+ T + +P T+ S+ + K D ++ HD FVA+ IPS
Sbjct: 187 VLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKT---DNFLRWLHHDASFVAA---IPST 240
Query: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA--- 289
+Y+ + ++ F +F E+++TS++ R+CK D
Sbjct: 241 QV-------VYFFFEETASEFDFF----------------ERLHTSRVARVCKNDVGGEK 277
Query: 290 -----FNSYVEVPIGCERSG-VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQ 343
+ ++++ + C + G + + +++ A L A + P ++ VF+
Sbjct: 278 LLQKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADS---------PTAPHIYAVFT--S 326
Query: 344 KRKMKSLDESALCIFILKQINDRIKERLQ---------SCYRGEGTLDLAWLKVKDIPCS 394
+ ++ SA+C F L I K + + + YRG T
Sbjct: 327 QWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPSSD 386
Query: 395 SALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYK-----NHSLAFVG 449
AL + D+F + + V G P+ + T + + +H + ++G
Sbjct: 387 KALTFMKDHFL---------MDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLG 437
Query: 450 TKSGKLKKSFGTGPQGGITQEWIGVEGDP 478
T +G L K+ +G E I + DP
Sbjct: 438 TTTGSLHKAVVSGDSSAHLVEEIQLFPDP 466
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 35.8 bits (81), Expect = 0.098
Identities = 92/395 (23%), Positives = 150/395 (37%), Gaps = 105/395 (26%)
Query: 11 LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTF----------RGEPAEGFNHLVVDE-- 58
LL LL++G G+ L +P PLS R ++ R PAEG + L +
Sbjct: 13 LLLLLLLLG-GAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
Query: 59 ---RTGHIYLGAVNRIYKL------SSDLKVL--VTHETGPDEDNPKCYPPRIVQTCNEP 107
RT +++G + +Y++ S++L+ +T + P + N + C
Sbjct: 72 RVNRT--LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECR-- 127
Query: 108 LTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRLEDLFKLGE--------PYHKKEH 158
N V +LL D E+ L CGS + +C ++ L +G+ PY K
Sbjct: 128 ----NFVKVLLLRD--ESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPK-- 179
Query: 159 YLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVF 218
+ + ++F D LF AT D F I D +
Sbjct: 180 -----HANVALFS--------DGMLFTATVTD-----FLAI-----------DAVIYRSL 210
Query: 219 HDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTS 278
D +K S F + Y+V+ G+ VYF + M E+V S
Sbjct: 211 GDRPTLRTVKHDSKWFK-----EPYFVHAVEWGSHVYFFFREIAMEF----NYLEKVVVS 261
Query: 279 KLVRLCKEDTA---------FNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLG-RTLGV 328
++ R+CK D + S+++ + C G + Y + AV G +LG
Sbjct: 262 RVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH-----FYFNVLQAVTGVVSLGG 316
Query: 329 HPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQI 363
P ++ VFS S+ SA+C F L Q+
Sbjct: 317 RP---VVLAVFS----TPSNSIPGSAVCAFDLTQV 344
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 33.5 bits (75), Expect = 0.49
Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 24/166 (14%)
Query: 36 KQRSFVTFRG-EPAEGFNHLVVDERTGHIYLGAVNRIYKLS----SDLKVLVTHETGPDE 90
+ + +TF G + ++ ++DE +Y+GA + I+ D + +V +
Sbjct: 41 ESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVNIKDFQKIVWPVSYTRR 100
Query: 91 DNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRL-----E 144
D K I++ C N K+L Y + L ACG+ + IC + + +
Sbjct: 101 DECKWAGKDILKEC-------ANFIKVLKA-YNQTHLYACGTGAFHPICTYIEIGHHPED 152
Query: 145 DLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVD 190
++FKL + H+ +G +S ++ + +D +L+ TA D
Sbjct: 153 NIFKL-----ENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAAD 193
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 32.0 bits (71), Expect = 1.4
Identities = 50/207 (24%), Positives = 80/207 (38%), Gaps = 36/207 (17%)
Query: 1 MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAP--------LSQKQRSFVTFRGEPAEGFN 52
M W LL LL+ G GSS P L RS + + +
Sbjct: 1 MAPSAWAICWLLGGLLLHG-GSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLNLQ 59
Query: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPR------IVQTCNE 106
+ +DE ++LG ++ +Y L D + PD +PP+ V+ +
Sbjct: 60 AMYLDEYRDRLFLGGLDALYSLRLD-------QAWPD-PREVLWPPQPGQREECVRKGRD 111
Query: 107 PLTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNE 165
PLT N ++L + L+ACG+ +Q C L+ + H+ EH L E
Sbjct: 112 PLTECANFVRVLQ-PHNRTHLLACGTGAFQPTCALITVG---------HRGEHVLH--LE 159
Query: 166 SGSVFGVIVSYSNLDDKLFIATAVDGK 192
GSV + + F +T +DG+
Sbjct: 160 PGSVESGRGRCPHEPSRPFASTFIDGE 186
>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
Length = 1178
Score = 30.8 bits (68), Expect = 3.1
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 6/49 (12%)
Query: 460 GTGPQGGITQEWIGVEGDPPGANIASQEQMLCVYLQCSSHKAIS-DQRV 507
G+GP+GGI + +G G +QE++L ++ S H A S QRV
Sbjct: 235 GSGPEGGIVEPRVG-----GGLGSRAQEELLLLFTMASLHPAFSFHQRV 278
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 29.6 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 36 KQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKC 95
+Q+ T +GE E + L E T H+Y + N + KL S+LK L T KC
Sbjct: 2275 QQKVCDTLQGENKELLSQL---EETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKC 2331
>gi|7657015 hypothetical protein LOC51493 [Homo sapiens]
Length = 505
Score = 29.3 bits (64), Expect = 9.2
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRL---------CKEDTAFN 291
D++ YGF+ GN F PE V PG + +L+R KE A
Sbjct: 87 DVHSGYGFAIGNMAAFDMNDPEAVVSPGGVGFDINCGVRLLRTNLDESDVQPVKEQLAQA 146
Query: 292 SYVEVPIGCERSGV 305
+ +P+G GV
Sbjct: 147 MFDHIPVGVGSKGV 160
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,766,382
Number of Sequences: 37866
Number of extensions: 941756
Number of successful extensions: 1819
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1761
Number of HSP's gapped (non-prelim): 31
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.