Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 157412247
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo
sapiens]
(796 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sap... 1640 0.0
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 1280 0.0
gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 367 e-101
gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 367 e-101
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] 149 1e-35
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] 149 1e-35
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 53 1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens] 52 2e-06
gi|239741753 PREDICTED: hypothetical protein [Homo sapiens] 50 8e-06
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 50 1e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 50 1e-05
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 49 2e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 48 3e-05
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 48 4e-05
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 48 4e-05
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 48 4e-05
gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ... 48 4e-05
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 48 4e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 48 4e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 48 4e-05
gi|60460889 Myb protein P42POP [Homo sapiens] 47 5e-05
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 47 7e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 47 9e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 47 9e-05
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 47 9e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 47 9e-05
gi|19913396 smoothelin isoform b [Homo sapiens] 47 9e-05
gi|19913394 smoothelin isoform c [Homo sapiens] 47 9e-05
>gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo
sapiens]
Length = 796
Score = 1640 bits (4247), Expect = 0.0
Identities = 796/796 (100%), Positives = 796/796 (100%)
Query: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60
MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV
Sbjct: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60
Query: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120
DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS
Sbjct: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120
Query: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180
VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS
Sbjct: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180
Query: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240
NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE
Sbjct: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240
Query: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300
KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR
Sbjct: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300
Query: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360
SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG
Sbjct: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360
Query: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420
SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI
Sbjct: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420
Query: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480
AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL
Sbjct: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480
Query: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540
QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA
Sbjct: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540
Query: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600
DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI
Sbjct: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600
Query: 601 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA 660
LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA
Sbjct: 601 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA 660
Query: 661 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP 720
QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP
Sbjct: 661 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP 720
Query: 721 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR 780
PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR
Sbjct: 721 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR 780
Query: 781 DGMEGLVPVGYTSLVL 796
DGMEGLVPVGYTSLVL
Sbjct: 781 DGMEGLVPVGYTSLVL 796
>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo
sapiens]
Length = 902
Score = 1280 bits (3312), Expect = 0.0
Identities = 621/621 (100%), Positives = 621/621 (100%)
Query: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60
MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV
Sbjct: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60
Query: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120
DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS
Sbjct: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120
Query: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180
VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS
Sbjct: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180
Query: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240
NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE
Sbjct: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240
Query: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300
KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR
Sbjct: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300
Query: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360
SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG
Sbjct: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360
Query: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420
SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI
Sbjct: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420
Query: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480
AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL
Sbjct: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480
Query: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540
QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA
Sbjct: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540
Query: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600
DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI
Sbjct: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600
Query: 601 LGLLNTKQLELWFSSLQEDAG 621
LGLLNTKQLELWFSSLQEDAG
Sbjct: 601 LGLLNTKQLELWFSSLQEDAG 621
Score = 367 bits (941), Expect = e-101
Identities = 176/176 (100%), Positives = 176/176 (100%)
Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680
GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR
Sbjct: 727 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 786
Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740
LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH
Sbjct: 787 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 846
Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796
RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
Sbjct: 847 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 902
Score = 30.8 bits (68), Expect = 5.2
Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%)
Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454
L PP+ P PP PP P LQ + GR G AA +P L
Sbjct: 673 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 726
Query: 455 SSW 457
SW
Sbjct: 727 GSW 729
>gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo
sapiens]
Length = 492
Score = 367 bits (941), Expect = e-101
Identities = 176/176 (100%), Positives = 176/176 (100%)
Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680
GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR
Sbjct: 317 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 376
Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740
LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH
Sbjct: 377 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 436
Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796
RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
Sbjct: 437 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 492
Score = 336 bits (862), Expect = 4e-92
Identities = 175/189 (92%), Positives = 177/189 (93%), Gaps = 2/189 (1%)
Query: 433 PAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS 492
P +PA + QAG VRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS
Sbjct: 25 PPRAPSSPALQALAGQAG--VRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS 82
Query: 493 VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT 552
VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT
Sbjct: 83 VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT 142
Query: 553 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW 612
GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW
Sbjct: 143 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW 202
Query: 613 FSSLQEDAG 621
FSSLQEDAG
Sbjct: 203 FSSLQEDAG 211
Score = 30.8 bits (68), Expect = 5.2
Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%)
Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454
L PP+ P PP PP P LQ + GR G AA +P L
Sbjct: 263 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 316
Query: 455 SSW 457
SW
Sbjct: 317 GSW 319
>gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo
sapiens]
Length = 433
Score = 367 bits (941), Expect = e-101
Identities = 176/176 (100%), Positives = 176/176 (100%)
Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680
GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR
Sbjct: 258 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 317
Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740
LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH
Sbjct: 318 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 377
Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796
RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
Sbjct: 378 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 433
Score = 295 bits (754), Expect = 1e-79
Identities = 152/152 (100%), Positives = 152/152 (100%)
Query: 470 MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT 529
MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT
Sbjct: 1 MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT 60
Query: 530 TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL 589
TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL
Sbjct: 61 TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL 120
Query: 590 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG 621
SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG
Sbjct: 121 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG 152
Score = 30.8 bits (68), Expect = 5.2
Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%)
Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454
L PP+ P PP PP P LQ + GR G AA +P L
Sbjct: 204 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 257
Query: 455 SSW 457
SW
Sbjct: 258 GSW 260
>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 149 bits (376), Expect = 1e-35
Identities = 75/134 (55%), Positives = 102/134 (76%)
Query: 483 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542
QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG
Sbjct: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051
Query: 543 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602
LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG
Sbjct: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111
Query: 603 LLNTKQLELWFSSL 616
LLN + LE WF+ L
Sbjct: 1112 LLNIRSLEFWFNHL 1125
Score = 84.7 bits (208), Expect = 3e-16
Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%)
Query: 623 WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661
WW QL Q+S+VY G EG SR+ G +++E EGA+
Sbjct: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326
Query: 662 ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697
P + + RG W+G G PAENE GA +
Sbjct: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386
Query: 698 ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737
+R PS WL S+ LV + G+ E P P+E E +P +
Sbjct: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445
Query: 738 QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
+ V+ALC H A P QLSF +G++LRV+ DWLRC R GLVP+ Y +L
Sbjct: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503
>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 149 bits (376), Expect = 1e-35
Identities = 75/134 (55%), Positives = 102/134 (76%)
Query: 483 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542
QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG
Sbjct: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051
Query: 543 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602
LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG
Sbjct: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111
Query: 603 LLNTKQLELWFSSL 616
LLN + LE WF+ L
Sbjct: 1112 LLNIRSLEFWFNHL 1125
Score = 84.7 bits (208), Expect = 3e-16
Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%)
Query: 623 WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661
WW QL Q+S+VY G EG SR+ G +++E EGA+
Sbjct: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326
Query: 662 ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697
P + + RG W+G G PAENE GA +
Sbjct: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386
Query: 698 ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737
+R PS WL S+ LV + G+ E P P+E E +P +
Sbjct: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445
Query: 738 QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
+ V+ALC H A P QLSF +G++LRV+ DWLRC R GLVP+ Y +L
Sbjct: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%)
Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251
+ E+ + ++ P++ ++D K + + K +P+ ++ K T E
Sbjct: 48 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107
Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311
+ T K S + P + + + + D GS +D ID RS P P
Sbjct: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 166
Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369
+ AQ++ P + QA + P T +LP P +P ++ PP+
Sbjct: 167 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 225
Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426
T + ++ +AP PVP AL P RPP P PP + P LQP+ + GQ S
Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 284
Query: 427 EGRAVSPAAGEEAP 440
A P G+ P
Sbjct: 285 PSHAQPPLHGQGPP 298
Score = 36.6 bits (83), Expect = 0.094
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405
P T PP+G PG S+ PP + + S P P V ++ + A P PPPPP
Sbjct: 499 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557
Query: 406 VPP 408
P
Sbjct: 558 RSP 560
Score = 32.7 bits (73), Expect = 1.4
Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%)
Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402
P +L P P SS A P +T + L PP P PP G V P+PP
Sbjct: 432 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 483
Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440
PPP+ P + PG QP G + G ++ A G P
Sbjct: 484 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 533
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%)
Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251
+ E+ + ++ P++ ++D K + + K +P+ ++ K T E
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661
Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311
+ T K S + P + + + + D GS +D ID RS P P
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 720
Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369
+ AQ++ P + QA + P T +LP P +P ++ PP+
Sbjct: 721 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779
Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426
T + ++ +AP PVP AL P RPP P PP + P LQP+ + GQ S
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 838
Query: 427 EGRAVSPAAGEEAP 440
A P G+ P
Sbjct: 839 PSHAQPPLHGQGPP 852
Score = 36.6 bits (83), Expect = 0.094
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405
P T PP+G PG S+ PP + + S P P V ++ + A P PPPPP
Sbjct: 1053 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111
Query: 406 VPP 408
P
Sbjct: 1112 RSP 1114
Score = 32.7 bits (73), Expect = 1.4
Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%)
Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402
P +L P P SS A P +T + L PP P PP G V P+PP
Sbjct: 986 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 1037
Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440
PPP+ P + PG QP G + G ++ A G P
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 1087
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%)
Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251
+ E+ + ++ P++ ++D K + + K +P+ ++ K T E
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661
Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311
+ T K S + P + + + + D GS +D ID RS P P
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 720
Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369
+ AQ++ P + QA + P T +LP P +P ++ PP+
Sbjct: 721 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779
Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426
T + ++ +AP PVP AL P RPP P PP + P LQP+ + GQ S
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 838
Query: 427 EGRAVSPAAGEEAP 440
A P G+ P
Sbjct: 839 PSHAQPPLHGQGPP 852
Score = 36.6 bits (83), Expect = 0.094
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405
P T PP+G PG S+ PP + + S P P V ++ + A P PPPPP
Sbjct: 1053 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111
Query: 406 VPP 408
P
Sbjct: 1112 RSP 1114
Score = 32.7 bits (73), Expect = 1.4
Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%)
Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402
P +L P P SS A P +T + L PP P PP G V P+PP
Sbjct: 986 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 1037
Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440
PPP+ P + PG QP G + G ++ A G P
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 1087
>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 1015
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 32/213 (15%)
Query: 39 TPPPPGDTGGKESRGPCSGTLVDANSNS-PAVPCRCCQEHGPGLEN---------RQDPS 88
+PPP G + G C+G L+ ++ A P EHG G E D
Sbjct: 192 SPPPAGSQRTQAGSGHCAGGLLGHEKHAMDASPT----EHGVGQEEDGPEDASPTEHDVG 247
Query: 89 QEEEGA--ASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQGSP 146
QEE+G ASP++ G D SP E V + G EDA P + E+ P
Sbjct: 248 QEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVD---QQEDGPEDARPTEHGVDQEEDGP 304
Query: 147 LASA-----------GPGTCSPDSFCCSPDSCSGASSSP-DPGLDSNCNALTTCQDVPSP 194
++ GP SP + +SP + G+D +
Sbjct: 305 EDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHE 364
Query: 195 -GLEEEDERAEQDLPTSELLEADDGKIDAGKTE 226
G+++E++ E PT ++ +DG DA TE
Sbjct: 365 HGVDQEEDGPEDASPTEHGVDQEDGPEDARPTE 397
>gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]
Length = 274
Score = 50.1 bits (118), Expect = 8e-06
Identities = 42/114 (36%), Positives = 49/114 (42%), Gaps = 23/114 (20%)
Query: 358 PGGSSAPPREVTTFKELRSRSRAPAPPVPPRD------PPVGWALVPPRPPPPPVPPRRK 411
PGGS+ +E +E +R APP PPR PP+G L PRPPP PPR
Sbjct: 71 PGGSADKDQE----REPSLAARGTAPPAPPRQCLPTPCPPLGHGL-RPRPPPGTPPPRCP 125
Query: 412 KNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAK------EPGAQAGLEVRSSWSF 459
+ +A G A PA PA K PG AG VR S SF
Sbjct: 126 RT------LAPGPRGLFPAPPPAPARTGPAGKAAADRGRPGPAAGRRVRRSPSF 173
Score = 33.5 bits (75), Expect = 0.80
Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 8/78 (10%)
Query: 353 PPSGSPGGSSAPPREVTTFKELRSRSRAPA-PPVPPRDPPVGWALVPPRPPPPPVPPRRK 411
PP G+P PPR T R PA PP P R P G A R P P RR
Sbjct: 115 PPPGTP-----PPRCPRTLAP-GPRGLFPAPPPAPARTGPAGKA-AADRGRPGPAAGRRV 167
Query: 412 KNRPGLQPIAEGQSEEGR 429
+ P P Q+ GR
Sbjct: 168 RRSPSFPPFLLAQTRLGR 185
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 685 PGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVR 744
PGG E E A +R W P + + L+ G P+ + + Q V
Sbjct: 1108 PGGWWEGELQARGKKRQIGWFP--ANYVKLLSPGTSKITPTEPPKSTALAAVCQ----VI 1161
Query: 745 ALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
+ D+TA D+L+F +G+++ V+ D DW + +G GL P Y L
Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKL 1211
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 685 PGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVR 744
PGG E E A +R W P + + L+ G P+ + + Q V
Sbjct: 1108 PGGWWEGELQARGKKRQIGWFP--ANYVKLLSPGTSKITPTEPPKSTALAAVCQ----VI 1161
Query: 745 ALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
+ D+TA D+L+F +G+++ V+ D DW + +G GL P Y L
Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKL 1211
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 9/84 (10%)
Query: 354 PSGSPGGSSAPPREVTTFKELRSRSRAPA------PPVPPRDPPVGWALVPPRPPPPPVP 407
P SP S P++V T +RSR +P PP PP PP L PP PPPPP
Sbjct: 393 PRHSPWSSPKLPKKVQT---VRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPL 449
Query: 408 PRRKKNRPGLQPIAEGQSEEGRAV 431
P +K + + + Q RA+
Sbjct: 450 PEKKLITRNIAEVIKQQESAQRAL 473
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 48.1 bits (113), Expect = 3e-05
Identities = 43/147 (29%), Positives = 58/147 (39%), Gaps = 19/147 (12%)
Query: 284 TDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWL 343
T + K D G+ G ++S++ +P ITS + + PG V
Sbjct: 622 TPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA-DCPKPMVVTPGAAAVAAPS------- 673
Query: 344 IVFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL-VPPRP- 401
V +P LPP PG PP + P PP PP PP A+ VPP P
Sbjct: 674 -VLAPTLPLPPP--PGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
Query: 402 ------PPPPVPPRRKKNRPGLQPIAE 422
PPPP+ P PGL P+ +
Sbjct: 731 PAPPGVPPPPILPPLPPFPPGLFPVMQ 757
Score = 37.7 bits (86), Expect = 0.042
Identities = 77/335 (22%), Positives = 117/335 (34%), Gaps = 90/335 (26%)
Query: 198 EEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWK 257
+E E ++D SE E D+G D +T I T K +A
Sbjct: 1072 DESENDDEDTALSEASEKDEGDSDEEETV---------SIVTSKAEA------------- 1109
Query: 258 NNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSD--VSEEPVPHRTITS 315
+SS SE +F+S +++ ++ + A + + + V+EE +
Sbjct: 1110 ----TSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPED 1165
Query: 316 FHELAQKRKRGPGLPLVPQ--------------AKKDRSDWLI-------VFSPDTELPP 354
F + ++ PG P V A ++R L V P P
Sbjct: 1166 FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREP 1225
Query: 355 SGSPGGSSA--------PPREVTTFKELRSRSRAP-----APPVPPRDPPVGWA--LVPP 399
PG S PP + + S RAP P PP P+ L PP
Sbjct: 1226 PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP 1285
Query: 400 RPPPPPVPPRRKK----NRPGL--QPIAE-------------GQSEEGRAVSPAAGEEAP 440
RPP PP PP + + P + +P+AE +S+ V G E P
Sbjct: 1286 RPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPP 1345
Query: 441 AAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475
+ G +GL S S VPG+ + A + S
Sbjct: 1346 LS---GGSSGL----SLSSPQVPGSPFSYPAPSPS 1373
Score = 35.0 bits (79), Expect = 0.27
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 11/51 (21%)
Query: 361 SSAPPREVTTFKELRSRS-RAPAPPVPPRDPPVGWALVPPRPPPPPVPPRR 410
S+ PR VT + R+ AP PP+PP+ PP PPPPPV P +
Sbjct: 1520 STHDPRTVTL--DFRNAGIPAPPPPLPPQPPPP--------PPPPPVEPTK 1560
Score = 33.9 bits (76), Expect = 0.61
Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 9/87 (10%)
Query: 364 PPREVTTFKELRSRS-----RAPAPP-VPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGL 417
PP E T +R RAPAPP +PP +P A P PP P PP G
Sbjct: 410 PPEEPTATAAFGARDSGEFRRAPAPPPLPPAEP---LAKEKPGTPPGPPPPDTNSMELGG 466
Query: 418 QPIAEGQSEEGRAVSPAAGEEAPAAKE 444
+P E + E +PA E
Sbjct: 467 RPTFGWSPEPCDSPGTPTLESSPAGPE 493
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 47.8 bits (112), Expect = 4e-05
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 16/116 (13%)
Query: 347 SPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPP 399
S +PP+G G PP + + + APPVPP PP G + PP
Sbjct: 580 SETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP 639
Query: 400 RPPP-----PPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAG 450
PP PPVPP P + P + G P G+ P P +G
Sbjct: 640 VPPTGDSGAPPVPPTGDSGAPPVPP----TGDSGAPPVPPTGDAGPPPVPPTGDSG 691
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 20/115 (17%)
Query: 352 LPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPPRPP-- 402
+PP+G G PP + + + APPVPP PP G + PP PP
Sbjct: 618 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 677
Query: 403 ---PPPVPPRRKKNRP--------GLQPIAEGQSEEGRAVSPAAGEEAPAAKEPG 446
PPPVPP P G P+ E V P AP G
Sbjct: 678 DAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTG 732
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 16/111 (14%)
Query: 352 LPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPPRPPP- 403
+PP+G G PP + + + APPVPP PP G + PP PP
Sbjct: 596 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 655
Query: 404 ----PPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAG 450
PPVPP P + P + G P G+ P +G
Sbjct: 656 DSGAPPVPPTGDSGAPPVPPTGDA----GPPPVPPTGDSGAPPVPPTGDSG 702
>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
Length = 218
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%)
Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404
++SP LPP P PPR P PP PPR P L PPRPP P
Sbjct: 21 LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60
Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435
P+PP R P +A+ + ++SP++
Sbjct: 61 PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91
>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
sapiens]
Length = 218
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%)
Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404
++SP LPP P PPR P PP PPR P L PPRPP P
Sbjct: 21 LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60
Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435
P+PP R P +A+ + ++SP++
Sbjct: 61 PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91
>gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo
sapiens]
Length = 218
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%)
Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404
++SP LPP P PPR P PP PPR P L PPRPP P
Sbjct: 21 LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60
Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435
P+PP R P +A+ + ++SP++
Sbjct: 61 PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 47.8 bits (112), Expect = 4e-05
Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 12/91 (13%)
Query: 354 PSG--SPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWA-LVPPRP--------P 402
P+G SP S P R R SR PAP PP +G A VP RP P
Sbjct: 769 PAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGP 828
Query: 403 PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP 433
PP VP R + PG+ P GQ+ R SP
Sbjct: 829 PPQVPSRPNRAPPGV-PSRSGQASPSRPESP 858
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 47.8 bits (112), Expect = 4e-05
Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 7/68 (10%)
Query: 354 PSGSPGGSSAP--PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK 411
PSGSP SS P PR L ++ P PP PP PP PP PPPPP P
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPPPPPPPPLPPPT 2431
Query: 412 KNRPGLQP 419
+P + P
Sbjct: 2432 SPKPTILP 2439
Score = 34.7 bits (78), Expect = 0.36
Identities = 83/371 (22%), Positives = 125/371 (33%), Gaps = 71/371 (19%)
Query: 147 LASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDV-----PSPGLEEEDE 201
L P T S D SS PG S NAL+ V P + + +
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 202 RAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGN 261
E+ ++++ + GK P I P + + K K + +G
Sbjct: 185 SQEETTKKQKVVQKEQGK-------PEGIIKP--PLQQQPPKPIPKQQGPGRDPLQQDGT 235
Query: 262 VNSSWKSEPEKFDS---GWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHE 318
S +PEK S G + +TD K+ + D S I
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP--LQRDASRPQTKQADIV---- 289
Query: 319 LAQKRKRGPGL-PLVPQAKKDRSDWLIVFSPDTELPPSGSPG------GSSAPPREVTTF 371
RG + P +P K + P PP+ PG G + PP + +
Sbjct: 290 ------RGESVKPSLPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338
Query: 372 KELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK-------KNRPG----LQPI 420
+ ++ P PP PP G P +P P PP ++ +PG QP
Sbjct: 339 T--KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 421 AEGQS---EEGRAVSPA--AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475
G++ + G A P G P A++PG Q S A PG + Q
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ---------SPAKAPGPTK--TPVQQP 444
Query: 476 GTGQLQEQKKG 486
G G++ Q+ G
Sbjct: 445 GPGKIPAQQAG 455
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 31/170 (18%)
Query: 348 PDTELPPSGSPGGSSAPPREVTTFKEL------RSRSRAPAPPVPPRDPPVGWALV---- 397
P P+ PG + P ++V T K L +S ++AP P P P +
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 398 -----------PPRPP--------PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEE 438
P +PP PPP P K P A+ S++ + P +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
Query: 439 APAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAE--AQSGTGQLQEQKKG 486
PA P + S + P AQ+ A+ AQ T + + G
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Score = 30.4 bits (67), Expect = 6.7
Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 41/208 (19%)
Query: 322 KRKRGPGLPLVPQAKKDRSDWLIV-----FSPDTELPPSGSPGGSSAPPREVTTFKELRS 376
KR G L VP + + + V S + P SP +AP +++
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-------- 694
Query: 377 RSRAPAPPVPP----------------RDPPVGWALVPPRPP-PPPVPPRRKKNRPGLQP 419
S+AP P PP + PP +L P PP P VP + K P
Sbjct: 695 -SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK-----AP 748
Query: 420 IAEGQSEEGRAVSPAAG--EEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS-- 475
+A+ + ++ + V P + A +P + +V+S P + +QS
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 476 GTGQLQEQKKGLLIAVSVSVDKIISHFG 503
TG+ I S KIISH G
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPG 835
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 47.8 bits (112), Expect = 4e-05
Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 7/68 (10%)
Query: 354 PSGSPGGSSAP--PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK 411
PSGSP SS P PR L ++ P PP PP PP PP PPPPP P
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPPPPPPPPLPPPT 2431
Query: 412 KNRPGLQP 419
+P + P
Sbjct: 2432 SPKPTILP 2439
Score = 34.7 bits (78), Expect = 0.36
Identities = 83/371 (22%), Positives = 125/371 (33%), Gaps = 71/371 (19%)
Query: 147 LASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDV-----PSPGLEEEDE 201
L P T S D SS PG S NAL+ V P + + +
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 202 RAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGN 261
E+ ++++ + GK P I P + + K K + +G
Sbjct: 185 SQEETTKKQKVVQKEQGK-------PEGIIKP--PLQQQPPKPIPKQQGPGRDPLQQDGT 235
Query: 262 VNSSWKSEPEKFDS---GWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHE 318
S +PEK S G + +TD K+ + D S I
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP--LQRDASRPQTKQADIV---- 289
Query: 319 LAQKRKRGPGL-PLVPQAKKDRSDWLIVFSPDTELPPSGSPG------GSSAPPREVTTF 371
RG + P +P K + P PP+ PG G + PP + +
Sbjct: 290 ------RGESVKPSLPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338
Query: 372 KELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK-------KNRPG----LQPI 420
+ ++ P PP PP G P +P P PP ++ +PG QP
Sbjct: 339 T--KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 421 AEGQS---EEGRAVSPA--AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475
G++ + G A P G P A++PG Q S A PG + Q
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ---------SPAKAPGPTK--TPVQQP 444
Query: 476 GTGQLQEQKKG 486
G G++ Q+ G
Sbjct: 445 GPGKIPAQQAG 455
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 31/170 (18%)
Query: 348 PDTELPPSGSPGGSSAPPREVTTFKEL------RSRSRAPAPPVPPRDPPVGWALV---- 397
P P+ PG + P ++V T K L +S ++AP P P P +
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 398 -----------PPRPP--------PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEE 438
P +PP PPP P K P A+ S++ + P +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
Query: 439 APAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAE--AQSGTGQLQEQKKG 486
PA P + S + P AQ+ A+ AQ T + + G
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Score = 30.4 bits (67), Expect = 6.7
Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 41/208 (19%)
Query: 322 KRKRGPGLPLVPQAKKDRSDWLIV-----FSPDTELPPSGSPGGSSAPPREVTTFKELRS 376
KR G L VP + + + V S + P SP +AP +++
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-------- 694
Query: 377 RSRAPAPPVPP----------------RDPPVGWALVPPRPP-PPPVPPRRKKNRPGLQP 419
S+AP P PP + PP +L P PP P VP + K P
Sbjct: 695 -SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK-----AP 748
Query: 420 IAEGQSEEGRAVSPAAG--EEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS-- 475
+A+ + ++ + V P + A +P + +V+S P + +QS
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 476 GTGQLQEQKKGLLIAVSVSVDKIISHFG 503
TG+ I S KIISH G
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPG 835
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 47.4 bits (111), Expect = 5e-05
Identities = 40/144 (27%), Positives = 53/144 (36%), Gaps = 17/144 (11%)
Query: 304 SEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSP--GGS 361
S +P P + L++ R+ +K S SP+ PS +P GG
Sbjct: 141 SSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS------SPEPWARPSCTPQEGGC 194
Query: 362 ------SAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRP 415
+PP +L + +P PP PP PP A V P PP PP PPR
Sbjct: 195 PRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLS 254
Query: 416 GLQP---IAEGQSEEGRAVSPAAG 436
P Q E A+ AG
Sbjct: 255 ASDPSLDFLRAQQETANAIRELAG 278
Score = 36.2 bits (82), Expect = 0.12
Identities = 42/162 (25%), Positives = 56/162 (34%), Gaps = 19/162 (11%)
Query: 62 ANSNSPAVPCRCCQEHGPGLENRQD-----PSQEEEGAASPSD---PGCSSSLSSCSDLS 113
A S+ P P C Q + + R+D + + G++SP P C+ C
Sbjct: 139 APSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPK 198
Query: 114 PDESPVSVYLRDLPGDEDA-HPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASS 172
ESP L+ + A P P PL PLA P SP P S
Sbjct: 199 ERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPP----PPPRPPPTLS 254
Query: 173 SPDPGLD------SNCNALTTCQDVPSPGLEEEDERAEQDLP 208
+ DP LD NA+ GL + E LP
Sbjct: 255 ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLP 296
Score = 31.2 bits (69), Expect = 4.0
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 383 PPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442
PP+PP PP P PP P +PP K +P++ + AV A G
Sbjct: 308 PPLPPPPPP-------PPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR 360
Query: 443 KEPGA 447
E GA
Sbjct: 361 SEEGA 365
Score = 30.0 bits (66), Expect = 8.8
Identities = 17/49 (34%), Positives = 21/49 (42%)
Query: 395 ALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAK 443
+L PP PPPPP PP + P P E E V+ AA+
Sbjct: 305 SLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 47.0 bits (110), Expect = 7e-05
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Query: 744 RALCDHTAARPDQLSFRRGEVLRVITTVD----EDWLRCGRDGMEGLVPVGYTSLV 795
RAL D+TA P +LSFRRG+VLRV+ + W C G +G+VP L+
Sbjct: 11 RALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL 66
Score = 31.2 bits (69), Expect = 4.0
Identities = 38/156 (24%), Positives = 54/156 (34%), Gaps = 12/156 (7%)
Query: 302 DVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGS 361
DV P P + E R+ GP + P K S L ++ EL G GG+
Sbjct: 189 DVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGT 248
Query: 362 SAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIA 421
+V S P + D L+ PPPP +RP L P A
Sbjct: 249 DEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPP--------HRPRL-PSA 299
Query: 422 EGQSEEGRAVSPAAGEEAPA---AKEPGAQAGLEVR 454
E S P +P+ + PG + ++ R
Sbjct: 300 ESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDR 335
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 46.6 bits (109), Expect = 9e-05
Identities = 41/156 (26%), Positives = 54/156 (34%), Gaps = 15/156 (9%)
Query: 303 VSEEPVPHRTITSFHELAQKRKRGP----GLPLVPQAKKDRSDWLIVFSPDTELPPSGSP 358
+S+ + R T +++ + K GP PQ + R + P P
Sbjct: 164 LSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223
Query: 359 GGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPP---------RPPPPPVPPR 409
GG PP R P PP PP PP G L PP RPPPP + P
Sbjct: 224 GGP--PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG 281
Query: 410 RKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEP 445
+ +P L P+ G P G P P
Sbjct: 282 QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317
Score = 34.7 bits (78), Expect = 0.36
Identities = 20/54 (37%), Positives = 22/54 (40%)
Query: 381 PAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPA 434
P PP P + PP PPRPP P PP P L G V+PA
Sbjct: 307 PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360
Score = 33.5 bits (75), Expect = 0.80
Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 14/74 (18%)
Query: 348 PDTELPP--SGSPGGSSAPPREVTTFKE------LRSRSRAPAPPVPPRDPPVGWALVPP 399
P LPP +G P PP V + L P PPVP PP G PP
Sbjct: 255 PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG--PPPP 312
Query: 400 R----PPPPPVPPR 409
+ PPP P PPR
Sbjct: 313 QQGPPPPPGPFPPR 326
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 46.6 bits (109), Expect = 9e-05
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 17/174 (9%)
Query: 323 RKRGPGLPLVPQAKKDRSDWLIVFSPDTELP-------PSGSPGGSSAPPREVTTFKELR 375
+ RG G +AK DR+ L +P E+P PS +PG +PP V K +
Sbjct: 2328 KARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVD--KRAK 2385
Query: 376 SRSRAPAPPVPPRDPPVGWALVPPRP-PPPPVPPRRKKNRPGL-QPIAEGQSEEGRAVSP 433
+ PAPP P PP + P P P P P + P + ++ RA
Sbjct: 2386 APKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEE 2445
Query: 434 AAGEEAPAAKEPGAQAGLEVRSSWSFAGVP---GAQRLWMAEAQSGTGQLQEQK 484
+ A + PG +A L V+ P A+ + G G QE K
Sbjct: 2446 SG---AKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
Score = 39.3 bits (90), Expect = 0.015
Identities = 94/451 (20%), Positives = 156/451 (34%), Gaps = 54/451 (11%)
Query: 34 EGPLSTPPPPGDTGGKESRGPCSGTLVDANSNSPAV---PCRCCQEHGPGLENRQDPSQE 90
+ P + P PP + + C A +PA P + ++ + E
Sbjct: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444
Query: 91 EEGAASPSDPGCSSSLSSCSDLSPDESPVS------VYLRDLPGDEDAHPQPSIIPLEQG 144
E GA P PG + L D SP S + LR+ PG S++ L
Sbjct: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504
Query: 145 SPLASAGPGTCSPDSFCCSPDSCSG-ASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERA 203
P A G+ P + P + G + P PGL T +D +P ++ + A
Sbjct: 2505 PPAA----GSSEPKAPW--PKATDGDLAQEPGPGL--------TFEDSGNPKSPDKAQ-A 2549
Query: 204 EQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGNVN 263
EQD A++ + + + S + +T+ E + +N + G G N
Sbjct: 2550 EQD-------GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR-N 2601
Query: 264 SSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKR 323
S S + +++ + S S + + S S + +S +
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
Query: 324 KRGPGLPLVPQAKKDRSDWLIVFSPDTELP-PSGSPGGSSAPPREVTTFKELRSRSRAPA 382
+D S S D P P+ P +A P + T ++ P+
Sbjct: 2662 SSSSSSSSSSTTDEDSS----CSSDDEAAPAPTAGPSAQAALPTKATK----QAGKARPS 2713
Query: 383 PPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442
P + P A P PPP P P + K + G + + + EG + P E A
Sbjct: 2714 AHSPGKKTP---APQPQAPPPQPTQPLQPKAQAGAK--SRPKKREGVHL-PTTKELAKRQ 2767
Query: 443 KEPGAQ------AGLEVRSSWSFAGVPGAQR 467
+ P + A L R W + G P +R
Sbjct: 2768 RLPSVENRPKIAAFLPARQLWKWFGKPTQRR 2798
Score = 37.4 bits (85), Expect = 0.055
Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 15/205 (7%)
Query: 30 PELQEGPLSTPPPPG----DTGGKES--RGPCSGTLVDANSNSPAVPCRCCQEHGPGLEN 83
P+ +G L+ P PG D+G +S + + + +S + +
Sbjct: 2518 PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577
Query: 84 RQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQ 143
+ EEEG + D GC + +CS S + P + S
Sbjct: 2578 GSETEGEEEGDKN-GDGGCGTGGRNCSAASSRAAS--------PASSSSSSSSSSSSSSS 2628
Query: 144 GSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERA 203
S +S+ + S S S S S +SSS S+ ++ +T + S ++E A
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPA 2688
Query: 204 EQDLPTSELLEADDGKIDAGKTEPS 228
P+++ AGK PS
Sbjct: 2689 PTAGPSAQAALPTKATKQAGKARPS 2713
Score = 31.2 bits (69), Expect = 4.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 28/116 (24%)
Query: 378 SRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPA--- 434
S P PP PP+ PP PP P G+ + Q E R V+P
Sbjct: 333 SPLPPPPAPPKGPPA---------PPAATP-------AGVYTVFREQGREHRVVAPTFVP 376
Query: 435 ---AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGL 487
A +E P + +QA + R+ AG PG + +A G+ + ++ +GL
Sbjct: 377 SVEAFDERPGPIQIASQA-RDARAREREAGRPG-----VLQAPPGSPRPLDRPEGL 426
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 46.6 bits (109), Expect = 9e-05
Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 706 PPTVSVLA---LVKRGAPPEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRG 762
PP+ S L L GA E E+ A + AV +T +LSFRRG
Sbjct: 712 PPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVACFA-YTGRTAQELSFRRG 770
Query: 763 EVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
+VLR+ DW R +GM GL+P Y +L
Sbjct: 771 DVLRLHERASSDWWRGEHNGMRGLIPHKYITL 802
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 46.6 bits (109), Expect = 9e-05
Identities = 40/147 (27%), Positives = 53/147 (36%), Gaps = 19/147 (12%)
Query: 305 EEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGSSAP 364
++P P +S +AQ PG+ P A P + PP PG + P
Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP---ATPPTSGAPPGSGPGPTPTP 153
Query: 365 PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQ 424
P VT+ AP PP P G PP+ PP PP PG P
Sbjct: 154 PPAVTS---------APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG-PGPGP----- 198
Query: 425 SEEGRAVSPAAGEEAPAAKEPGAQAGL 451
++G G + P +PG GL
Sbjct: 199 -KQGPGPGGPKGGKMPGGPKPGGGPGL 224
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 354 PSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKN 413
P G G S P + + + + P PP+ PP P +PPP P P ++++
Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP------PHQPPPHPQPHQQQQP 99
Query: 414 RPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442
P Q ++ +G +P G PA+
Sbjct: 100 PPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128
Score = 35.4 bits (80), Expect = 0.21
Identities = 36/143 (25%), Positives = 44/143 (30%), Gaps = 18/143 (12%)
Query: 326 GPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSP-------GGSSAPPREVTTFKELRSRS 378
GP P+ P + P + PP P PP + K + ++
Sbjct: 55 GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114
Query: 379 RAPAPPV----------PPRDPPVGWALVPPRPPPPPVPPRRKKNR-PGLQPIAEGQSEE 427
PAP V PP PP A P P P PP + PG P S
Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174
Query: 428 GRAVSPAAGEEAPAAKEPGAQAG 450
A G P A PG G
Sbjct: 175 PTTPPQAGGPPPPPAAVPGPGPG 197
Score = 32.7 bits (73), Expect = 1.4
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 18/91 (19%)
Query: 375 RSRSRAPAPPVPP----RDPPVGWALVPPRPPPPPVPPRRKKNRPGLQP----------- 419
+S + P PP PP + PP PP+ PPP PP + QP
Sbjct: 53 QSGPKPPIPPPPPHQQQQQPPPQQP--PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV 110
Query: 420 IAEGQS-EEGRAVSPAAGEEAPAAKEPGAQA 449
+A+G G +P A AP A P + A
Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 46.6 bits (109), Expect = 9e-05
Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 18/108 (16%)
Query: 354 PSGSPGGSS-----------APPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL---VPP 399
P+ +P G+S APP ++ S S PA P PP +P L VP
Sbjct: 173 PTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPG 232
Query: 400 RPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP--AAGEEAPAAKEP 445
P PPP PP+ P P S EG+ V+ + +E PAA+ P
Sbjct: 233 SPEPPPSPPKTTSPEPQESPTL--PSTEGQVVNKLLSGPKETPAAQSP 278
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 46.6 bits (109), Expect = 9e-05
Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 18/108 (16%)
Query: 354 PSGSPGGSS-----------APPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL---VPP 399
P+ +P G+S APP ++ S S PA P PP +P L VP
Sbjct: 173 PTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPG 232
Query: 400 RPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP--AAGEEAPAAKEP 445
P PPP PP+ P P S EG+ V+ + +E PAA+ P
Sbjct: 233 SPEPPPSPPKTTSPEPQESPTL--PSTEGQVVNKLLSGPKETPAAQSP 278
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,173,255
Number of Sequences: 37866
Number of extensions: 2748123
Number of successful extensions: 25576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 394
Number of HSP's successfully gapped in prelim test: 1130
Number of HSP's that attempted gapping in prelim test: 14144
Number of HSP's gapped (non-prelim): 7772
length of query: 796
length of database: 18,247,518
effective HSP length: 110
effective length of query: 686
effective length of database: 14,082,258
effective search space: 9660428988
effective search space used: 9660428988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.