Guide to the Human Genome
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Search of human proteins with 157412247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo
sapiens]
         (796 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sap...  1640   0.0  
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap...  1280   0.0  
gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap...   367   e-101
gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi...   367   e-101
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]           149   1e-35
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]            149   1e-35
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          53   1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          53   1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          53   1e-06
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]           52   2e-06
gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]            50   8e-06
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                50   1e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                50   1e-05
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      49   2e-05
gi|210032580 SET domain containing 1B [Homo sapiens]                   48   3e-05
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            48   4e-05
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ...    48   4e-05
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ...    48   4e-05
gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ...    48   4e-05
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                         48   4e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          48   4e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          48   4e-05
gi|60460889 Myb protein P42POP [Homo sapiens]                          47   5e-05
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...    47   7e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    47   9e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         47   9e-05
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]            47   9e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    47   9e-05
gi|19913396 smoothelin isoform b [Homo sapiens]                        47   9e-05
gi|19913394 smoothelin isoform c [Homo sapiens]                        47   9e-05

>gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo
           sapiens]
          Length = 796

 Score = 1640 bits (4247), Expect = 0.0
 Identities = 796/796 (100%), Positives = 796/796 (100%)

Query: 1   MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60
           MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV
Sbjct: 1   MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60

Query: 61  DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120
           DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS
Sbjct: 61  DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120

Query: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180
           VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS
Sbjct: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180

Query: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240
           NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE
Sbjct: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240

Query: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300
           KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR
Sbjct: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300

Query: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360
           SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG
Sbjct: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360

Query: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420
           SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI
Sbjct: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420

Query: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480
           AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL
Sbjct: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480

Query: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540
           QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA
Sbjct: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540

Query: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600
           DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI
Sbjct: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600

Query: 601 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA 660
           LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA
Sbjct: 601 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA 660

Query: 661 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP 720
           QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP
Sbjct: 661 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP 720

Query: 721 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR 780
           PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR
Sbjct: 721 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR 780

Query: 781 DGMEGLVPVGYTSLVL 796
           DGMEGLVPVGYTSLVL
Sbjct: 781 DGMEGLVPVGYTSLVL 796


>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo
           sapiens]
          Length = 902

 Score = 1280 bits (3312), Expect = 0.0
 Identities = 621/621 (100%), Positives = 621/621 (100%)

Query: 1   MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60
           MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV
Sbjct: 1   MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60

Query: 61  DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120
           DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS
Sbjct: 61  DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120

Query: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180
           VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS
Sbjct: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180

Query: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240
           NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE
Sbjct: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240

Query: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300
           KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR
Sbjct: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300

Query: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360
           SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG
Sbjct: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360

Query: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420
           SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI
Sbjct: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420

Query: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480
           AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL
Sbjct: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480

Query: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540
           QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA
Sbjct: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540

Query: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600
           DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI
Sbjct: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600

Query: 601 LGLLNTKQLELWFSSLQEDAG 621
           LGLLNTKQLELWFSSLQEDAG
Sbjct: 601 LGLLNTKQLELWFSSLQEDAG 621



 Score =  367 bits (941), Expect = e-101
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680
           GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR
Sbjct: 727 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 786

Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740
           LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH
Sbjct: 787 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 846

Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796
           RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
Sbjct: 847 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 902



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%)

Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454
           L PP+ P PP PP      P LQ   +      GR      G    AA +P     L   
Sbjct: 673 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 726

Query: 455 SSW 457
            SW
Sbjct: 727 GSW 729


>gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo
           sapiens]
          Length = 492

 Score =  367 bits (941), Expect = e-101
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680
           GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR
Sbjct: 317 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 376

Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740
           LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH
Sbjct: 377 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 436

Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796
           RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
Sbjct: 437 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 492



 Score =  336 bits (862), Expect = 4e-92
 Identities = 175/189 (92%), Positives = 177/189 (93%), Gaps = 2/189 (1%)

Query: 433 PAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS 492
           P     +PA +    QAG  VRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS
Sbjct: 25  PPRAPSSPALQALAGQAG--VRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS 82

Query: 493 VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT 552
           VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT
Sbjct: 83  VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT 142

Query: 553 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW 612
           GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW
Sbjct: 143 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW 202

Query: 613 FSSLQEDAG 621
           FSSLQEDAG
Sbjct: 203 FSSLQEDAG 211



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%)

Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454
           L PP+ P PP PP      P LQ   +      GR      G    AA +P     L   
Sbjct: 263 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 316

Query: 455 SSW 457
            SW
Sbjct: 317 GSW 319


>gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo
           sapiens]
          Length = 433

 Score =  367 bits (941), Expect = e-101
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680
           GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR
Sbjct: 258 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 317

Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740
           LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH
Sbjct: 318 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 377

Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796
           RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
Sbjct: 378 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 433



 Score =  295 bits (754), Expect = 1e-79
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 470 MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT 529
           MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT
Sbjct: 1   MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT 60

Query: 530 TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL 589
           TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL
Sbjct: 61  TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL 120

Query: 590 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG 621
           SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG
Sbjct: 121 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG 152



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%)

Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454
           L PP+ P PP PP      P LQ   +      GR      G    AA +P     L   
Sbjct: 204 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 257

Query: 455 SSW 457
            SW
Sbjct: 258 GSW 260


>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score =  149 bits (376), Expect = 1e-35
 Identities = 75/134 (55%), Positives = 102/134 (76%)

Query: 483  QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542
            QKKGL+ AV+++VD I++HFG +R+   KA+LG+S +SP+VGHLVL  LCPA+ A++ DG
Sbjct: 992  QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051

Query: 543  LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602
            LK F  D+I GQR++ PWSVVEAS + G ST+ L  LY++VS+   L+S   RF+AFILG
Sbjct: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111

Query: 603  LLNTKQLELWFSSL 616
            LLN + LE WF+ L
Sbjct: 1112 LLNIRSLEFWFNHL 1125



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%)

Query: 623  WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661
            WW QL Q+S+VY  G  EG   SR+  G   +++E                     EGA+
Sbjct: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326

Query: 662  ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697
              P   + +   RG   W+G                 G    PAENE GA +        
Sbjct: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386

Query: 698  ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737
                            +R PS WL    S+  LV +  G+  E P P+E   E  +P + 
Sbjct: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445

Query: 738  QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
             +    V+ALC H A  P QLSF +G++LRV+     DWLRC R    GLVP+ Y +L
Sbjct: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503


>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score =  149 bits (376), Expect = 1e-35
 Identities = 75/134 (55%), Positives = 102/134 (76%)

Query: 483  QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542
            QKKGL+ AV+++VD I++HFG +R+   KA+LG+S +SP+VGHLVL  LCPA+ A++ DG
Sbjct: 992  QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051

Query: 543  LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602
            LK F  D+I GQR++ PWSVVEAS + G ST+ L  LY++VS+   L+S   RF+AFILG
Sbjct: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111

Query: 603  LLNTKQLELWFSSL 616
            LLN + LE WF+ L
Sbjct: 1112 LLNIRSLEFWFNHL 1125



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%)

Query: 623  WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661
            WW QL Q+S+VY  G  EG   SR+  G   +++E                     EGA+
Sbjct: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326

Query: 662  ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697
              P   + +   RG   W+G                 G    PAENE GA +        
Sbjct: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386

Query: 698  ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737
                            +R PS WL    S+  LV +  G+  E P P+E   E  +P + 
Sbjct: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445

Query: 738  QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
             +    V+ALC H A  P QLSF +G++LRV+     DWLRC R    GLVP+ Y +L
Sbjct: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%)

Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251
           + E+   + ++ P++    ++D K +    + K       +P+     ++ K    T E 
Sbjct: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107

Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311
           + T  K       S  + P + +     +  + D GS +D   ID   RS     P P  
Sbjct: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 166

Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369
             +     AQ++      P + QA    +       P T +LP P  +P  ++ PP+   
Sbjct: 167 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 225

Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426
           T  +  ++ +AP  PVP        AL P RPP P  PP    + P LQP+  + GQ S 
Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 284

Query: 427 EGRAVSPAAGEEAP 440
              A  P  G+  P
Sbjct: 285 PSHAQPPLHGQGPP 298



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405
           P T  PP+G PG S+ PP      +   +   S  P P V  ++  +  A  P  PPPPP
Sbjct: 499 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557

Query: 406 VPP 408
             P
Sbjct: 558 RSP 560



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%)

Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402
           P  +L P   P  SS A P  +T  + L        PP P   PP G   V P+PP    
Sbjct: 432 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 483

Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440
                 PPP+ P    +       PG   QP   G +  G ++  A G   P
Sbjct: 484 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 533


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%)

Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251
           + E+   + ++ P++    ++D K +    + K       +P+     ++ K    T E 
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311
           + T  K       S  + P + +     +  + D GS +D   ID   RS     P P  
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 720

Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369
             +     AQ++      P + QA    +       P T +LP P  +P  ++ PP+   
Sbjct: 721 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779

Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426
           T  +  ++ +AP  PVP        AL P RPP P  PP    + P LQP+  + GQ S 
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 838

Query: 427 EGRAVSPAAGEEAP 440
              A  P  G+  P
Sbjct: 839 PSHAQPPLHGQGPP 852



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 348  PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405
            P T  PP+G PG S+ PP      +   +   S  P P V  ++  +  A  P  PPPPP
Sbjct: 1053 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111

Query: 406  VPP 408
              P
Sbjct: 1112 RSP 1114



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%)

Query: 348  PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402
            P  +L P   P  SS A P  +T  + L        PP P   PP G   V P+PP    
Sbjct: 986  PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 1037

Query: 403  ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440
                  PPP+ P    +       PG   QP   G +  G ++  A G   P
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 1087


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%)

Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251
           + E+   + ++ P++    ++D K +    + K       +P+     ++ K    T E 
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311
           + T  K       S  + P + +     +  + D GS +D   ID   RS     P P  
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 720

Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369
             +     AQ++      P + QA    +       P T +LP P  +P  ++ PP+   
Sbjct: 721 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779

Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426
           T  +  ++ +AP  PVP        AL P RPP P  PP    + P LQP+  + GQ S 
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 838

Query: 427 EGRAVSPAAGEEAP 440
              A  P  G+  P
Sbjct: 839 PSHAQPPLHGQGPP 852



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 348  PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405
            P T  PP+G PG S+ PP      +   +   S  P P V  ++  +  A  P  PPPPP
Sbjct: 1053 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111

Query: 406  VPP 408
              P
Sbjct: 1112 RSP 1114



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%)

Query: 348  PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402
            P  +L P   P  SS A P  +T  + L        PP P   PP G   V P+PP    
Sbjct: 986  PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 1037

Query: 403  ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440
                  PPP+ P    +       PG   QP   G +  G ++  A G   P
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 1087


>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1015

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 32/213 (15%)

Query: 39  TPPPPGDTGGKESRGPCSGTLVDANSNS-PAVPCRCCQEHGPGLEN---------RQDPS 88
           +PPP G    +   G C+G L+    ++  A P     EHG G E            D  
Sbjct: 192 SPPPAGSQRTQAGSGHCAGGLLGHEKHAMDASPT----EHGVGQEEDGPEDASPTEHDVG 247

Query: 89  QEEEGA--ASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQGSP 146
           QEE+G   ASP++ G         D SP E  V    +   G EDA P    +  E+  P
Sbjct: 248 QEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVD---QQEDGPEDARPTEHGVDQEEDGP 304

Query: 147 LASA-----------GPGTCSPDSFCCSPDSCSGASSSP-DPGLDSNCNALTTCQDVPSP 194
             ++           GP   SP       +      +SP + G+D   +           
Sbjct: 305 EDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHE 364

Query: 195 -GLEEEDERAEQDLPTSELLEADDGKIDAGKTE 226
            G+++E++  E   PT   ++ +DG  DA  TE
Sbjct: 365 HGVDQEEDGPEDASPTEHGVDQEDGPEDARPTE 397


>gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 42/114 (36%), Positives = 49/114 (42%), Gaps = 23/114 (20%)

Query: 358 PGGSSAPPREVTTFKELRSRSRAPAPPVPPRD------PPVGWALVPPRPPPPPVPPRRK 411
           PGGS+   +E    +E    +R  APP PPR       PP+G  L  PRPPP   PPR  
Sbjct: 71  PGGSADKDQE----REPSLAARGTAPPAPPRQCLPTPCPPLGHGL-RPRPPPGTPPPRCP 125

Query: 412 KNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAK------EPGAQAGLEVRSSWSF 459
           +       +A G      A  PA     PA K       PG  AG  VR S SF
Sbjct: 126 RT------LAPGPRGLFPAPPPAPARTGPAGKAAADRGRPGPAAGRRVRRSPSF 173



 Score = 33.5 bits (75), Expect = 0.80
 Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 8/78 (10%)

Query: 353 PPSGSPGGSSAPPREVTTFKELRSRSRAPA-PPVPPRDPPVGWALVPPRPPPPPVPPRRK 411
           PP G+P     PPR   T      R   PA PP P R  P G A    R  P P   RR 
Sbjct: 115 PPPGTP-----PPRCPRTLAP-GPRGLFPAPPPAPARTGPAGKA-AADRGRPGPAAGRRV 167

Query: 412 KNRPGLQPIAEGQSEEGR 429
           +  P   P    Q+  GR
Sbjct: 168 RRSPSFPPFLLAQTRLGR 185


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 685  PGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVR 744
            PGG  E E  A   +R   W P   + + L+  G     P+      +   + Q    V 
Sbjct: 1108 PGGWWEGELQARGKKRQIGWFP--ANYVKLLSPGTSKITPTEPPKSTALAAVCQ----VI 1161

Query: 745  ALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
             + D+TA   D+L+F +G+++ V+   D DW +   +G  GL P  Y  L
Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKL 1211


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 685  PGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVR 744
            PGG  E E  A   +R   W P   + + L+  G     P+      +   + Q    V 
Sbjct: 1108 PGGWWEGELQARGKKRQIGWFP--ANYVKLLSPGTSKITPTEPPKSTALAAVCQ----VI 1161

Query: 745  ALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
             + D+TA   D+L+F +G+++ V+   D DW +   +G  GL P  Y  L
Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKL 1211


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 354 PSGSPGGSSAPPREVTTFKELRSRSRAPA------PPVPPRDPPVGWALVPPRPPPPPVP 407
           P  SP  S   P++V T   +RSR  +P       PP PP  PP    L PP PPPPP  
Sbjct: 393 PRHSPWSSPKLPKKVQT---VRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPL 449

Query: 408 PRRKKNRPGLQPIAEGQSEEGRAV 431
           P +K     +  + + Q    RA+
Sbjct: 450 PEKKLITRNIAEVIKQQESAQRAL 473


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 43/147 (29%), Positives = 58/147 (39%), Gaps = 19/147 (12%)

Query: 284 TDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWL 343
           T +  K D G+   G   ++S++ +P   ITS  +  +     PG   V           
Sbjct: 622 TPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA-DCPKPMVVTPGAAAVAAPS------- 673

Query: 344 IVFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL-VPPRP- 401
            V +P   LPP   PG    PP       +       P PP PP  PP   A+ VPP P 
Sbjct: 674 -VLAPTLPLPPP--PGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730

Query: 402 ------PPPPVPPRRKKNRPGLQPIAE 422
                 PPPP+ P      PGL P+ +
Sbjct: 731 PAPPGVPPPPILPPLPPFPPGLFPVMQ 757



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 77/335 (22%), Positives = 117/335 (34%), Gaps = 90/335 (26%)

Query: 198  EEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWK 257
            +E E  ++D   SE  E D+G  D  +T           I T K +A             
Sbjct: 1072 DESENDDEDTALSEASEKDEGDSDEEETV---------SIVTSKAEA------------- 1109

Query: 258  NNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSD--VSEEPVPHRTITS 315
                 +SS  SE  +F+S  +++   ++   +  A + +     +  V+EE +       
Sbjct: 1110 ----TSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPED 1165

Query: 316  FHELAQKRKRGPGLPLVPQ--------------AKKDRSDWLI-------VFSPDTELPP 354
            F +  ++    PG P V                A ++R   L        V  P     P
Sbjct: 1166 FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREP 1225

Query: 355  SGSPGGSSA--------PPREVTTFKELRSRSRAP-----APPVPPRDPPVGWA--LVPP 399
               PG S          PP +    +   S  RAP       P PP   P+     L PP
Sbjct: 1226 PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP 1285

Query: 400  RPPPPPVPPRRKK----NRPGL--QPIAE-------------GQSEEGRAVSPAAGEEAP 440
            RPP PP PP   +    + P +  +P+AE              +S+    V    G E P
Sbjct: 1286 RPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPP 1345

Query: 441  AAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475
             +   G  +GL    S S   VPG+   + A + S
Sbjct: 1346 LS---GGSSGL----SLSSPQVPGSPFSYPAPSPS 1373



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 11/51 (21%)

Query: 361  SSAPPREVTTFKELRSRS-RAPAPPVPPRDPPVGWALVPPRPPPPPVPPRR 410
            S+  PR VT   + R+    AP PP+PP+ PP         PPPPPV P +
Sbjct: 1520 STHDPRTVTL--DFRNAGIPAPPPPLPPQPPPP--------PPPPPVEPTK 1560



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 9/87 (10%)

Query: 364 PPREVTTFKELRSRS-----RAPAPP-VPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGL 417
           PP E T      +R      RAPAPP +PP +P    A   P  PP P PP       G 
Sbjct: 410 PPEEPTATAAFGARDSGEFRRAPAPPPLPPAEP---LAKEKPGTPPGPPPPDTNSMELGG 466

Query: 418 QPIAEGQSEEGRAVSPAAGEEAPAAKE 444
           +P      E   +      E +PA  E
Sbjct: 467 RPTFGWSPEPCDSPGTPTLESSPAGPE 493


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 16/116 (13%)

Query: 347 SPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPP 399
           S    +PP+G  G    PP   +    +     + APPVPP         PP G +  PP
Sbjct: 580 SETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP 639

Query: 400 RPPP-----PPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAG 450
            PP      PPVPP      P + P      + G    P  G+  P    P   +G
Sbjct: 640 VPPTGDSGAPPVPPTGDSGAPPVPP----TGDSGAPPVPPTGDAGPPPVPPTGDSG 691



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 20/115 (17%)

Query: 352 LPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPPRPP-- 402
           +PP+G  G    PP   +    +     + APPVPP         PP G +  PP PP  
Sbjct: 618 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 677

Query: 403 ---PPPVPPRRKKNRP--------GLQPIAEGQSEEGRAVSPAAGEEAPAAKEPG 446
              PPPVPP      P        G  P+      E   V P     AP     G
Sbjct: 678 DAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTG 732



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 16/111 (14%)

Query: 352 LPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPPRPPP- 403
           +PP+G  G    PP   +    +     + APPVPP         PP G +  PP PP  
Sbjct: 596 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 655

Query: 404 ----PPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAG 450
               PPVPP      P + P  +     G    P  G+       P   +G
Sbjct: 656 DSGAPPVPPTGDSGAPPVPPTGDA----GPPPVPPTGDSGAPPVPPTGDSG 702


>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
           sapiens]
          Length = 218

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%)

Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404
           ++SP   LPP   P     PPR              P PP PPR P     L PPRPP P
Sbjct: 21  LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60

Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435
           P+PP R    P    +A+ +     ++SP++
Sbjct: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91


>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
           sapiens]
          Length = 218

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%)

Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404
           ++SP   LPP   P     PPR              P PP PPR P     L PPRPP P
Sbjct: 21  LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60

Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435
           P+PP R    P    +A+ +     ++SP++
Sbjct: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91


>gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo
           sapiens]
          Length = 218

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%)

Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404
           ++SP   LPP   P     PPR              P PP PPR P     L PPRPP P
Sbjct: 21  LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60

Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435
           P+PP R    P    +A+ +     ++SP++
Sbjct: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 12/91 (13%)

Query: 354 PSG--SPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWA-LVPPRP--------P 402
           P+G  SP  S  P R        R  SR PAP  PP    +G A  VP RP        P
Sbjct: 769 PAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGP 828

Query: 403 PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP 433
           PP VP R  +  PG+ P   GQ+   R  SP
Sbjct: 829 PPQVPSRPNRAPPGV-PSRSGQASPSRPESP 858


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 7/68 (10%)

Query: 354  PSGSPGGSSAP--PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK 411
            PSGSP  SS P  PR       L   ++ P PP PP  PP      PP PPPPP  P   
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPPPPPPPPLPPPT 2431

Query: 412  KNRPGLQP 419
              +P + P
Sbjct: 2432 SPKPTILP 2439



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 83/371 (22%), Positives = 125/371 (33%), Gaps = 71/371 (19%)

Query: 147 LASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDV-----PSPGLEEEDE 201
           L    P T S        D      SS  PG  S  NAL+    V     P   + + + 
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184

Query: 202 RAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGN 261
             E+     ++++ + GK       P   I P   +  +  K   K         + +G 
Sbjct: 185 SQEETTKKQKVVQKEQGK-------PEGIIKP--PLQQQPPKPIPKQQGPGRDPLQQDGT 235

Query: 262 VNSSWKSEPEKFDS---GWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHE 318
             S    +PEK  S   G     +      +TD  K+    + D S        I     
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP--LQRDASRPQTKQADIV---- 289

Query: 319 LAQKRKRGPGL-PLVPQAKKDRSDWLIVFSPDTELPPSGSPG------GSSAPPREVTTF 371
                 RG  + P +P   K       +  P    PP+  PG      G + PP + +  
Sbjct: 290 ------RGESVKPSLPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338

Query: 372 KELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK-------KNRPG----LQPI 420
              +  ++ P    PP  PP G    P +P  P  PP ++         +PG     QP 
Sbjct: 339 T--KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 421 AEGQS---EEGRAVSPA--AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475
             G++   + G A  P    G   P A++PG Q         S A  PG  +      Q 
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ---------SPAKAPGPTK--TPVQQP 444

Query: 476 GTGQLQEQKKG 486
           G G++  Q+ G
Sbjct: 445 GPGKIPAQQAG 455



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 31/170 (18%)

Query: 348 PDTELPPSGSPGGSSAPPREVTTFKEL------RSRSRAPAPPVPPRDPPVGWALV---- 397
           P     P+  PG +  P ++V T K L      +S ++AP P   P   P    +     
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454

Query: 398 -----------PPRPP--------PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEE 438
                      P +PP        PPP  P   K  P     A+  S++  +  P   + 
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514

Query: 439 APAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAE--AQSGTGQLQEQKKG 486
            PA   P      +  S    +  P AQ+   A+  AQ  T  + +   G
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 322 KRKRGPGLPLVPQAKKDRSDWLIV-----FSPDTELPPSGSPGGSSAPPREVTTFKELRS 376
           KR  G  L  VP + + +     V      S  +  P   SP   +AP +++        
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-------- 694

Query: 377 RSRAPAPPVPP----------------RDPPVGWALVPPRPP-PPPVPPRRKKNRPGLQP 419
            S+AP P  PP                + PP   +L  P PP  P VP  + K      P
Sbjct: 695 -SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK-----AP 748

Query: 420 IAEGQSEEGRAVSPAAG--EEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS-- 475
           +A+ + ++ + V P       + A  +P   +  +V+S       P  +      +QS  
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAKPSQSFP 807

Query: 476 GTGQLQEQKKGLLIAVSVSVDKIISHFG 503
            TG+         I    S  KIISH G
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPG 835


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 7/68 (10%)

Query: 354  PSGSPGGSSAP--PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK 411
            PSGSP  SS P  PR       L   ++ P PP PP  PP      PP PPPPP  P   
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPPPPPPPPLPPPT 2431

Query: 412  KNRPGLQP 419
              +P + P
Sbjct: 2432 SPKPTILP 2439



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 83/371 (22%), Positives = 125/371 (33%), Gaps = 71/371 (19%)

Query: 147 LASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDV-----PSPGLEEEDE 201
           L    P T S        D      SS  PG  S  NAL+    V     P   + + + 
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184

Query: 202 RAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGN 261
             E+     ++++ + GK       P   I P   +  +  K   K         + +G 
Sbjct: 185 SQEETTKKQKVVQKEQGK-------PEGIIKP--PLQQQPPKPIPKQQGPGRDPLQQDGT 235

Query: 262 VNSSWKSEPEKFDS---GWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHE 318
             S    +PEK  S   G     +      +TD  K+    + D S        I     
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP--LQRDASRPQTKQADIV---- 289

Query: 319 LAQKRKRGPGL-PLVPQAKKDRSDWLIVFSPDTELPPSGSPG------GSSAPPREVTTF 371
                 RG  + P +P   K       +  P    PP+  PG      G + PP + +  
Sbjct: 290 ------RGESVKPSLPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338

Query: 372 KELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK-------KNRPG----LQPI 420
              +  ++ P    PP  PP G    P +P  P  PP ++         +PG     QP 
Sbjct: 339 T--KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 421 AEGQS---EEGRAVSPA--AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475
             G++   + G A  P    G   P A++PG Q         S A  PG  +      Q 
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ---------SPAKAPGPTK--TPVQQP 444

Query: 476 GTGQLQEQKKG 486
           G G++  Q+ G
Sbjct: 445 GPGKIPAQQAG 455



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 31/170 (18%)

Query: 348 PDTELPPSGSPGGSSAPPREVTTFKEL------RSRSRAPAPPVPPRDPPVGWALV---- 397
           P     P+  PG +  P ++V T K L      +S ++AP P   P   P    +     
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454

Query: 398 -----------PPRPP--------PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEE 438
                      P +PP        PPP  P   K  P     A+  S++  +  P   + 
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514

Query: 439 APAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAE--AQSGTGQLQEQKKG 486
            PA   P      +  S    +  P AQ+   A+  AQ  T  + +   G
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 322 KRKRGPGLPLVPQAKKDRSDWLIV-----FSPDTELPPSGSPGGSSAPPREVTTFKELRS 376
           KR  G  L  VP + + +     V      S  +  P   SP   +AP +++        
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-------- 694

Query: 377 RSRAPAPPVPP----------------RDPPVGWALVPPRPP-PPPVPPRRKKNRPGLQP 419
            S+AP P  PP                + PP   +L  P PP  P VP  + K      P
Sbjct: 695 -SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK-----AP 748

Query: 420 IAEGQSEEGRAVSPAAG--EEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS-- 475
           +A+ + ++ + V P       + A  +P   +  +V+S       P  +      +QS  
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAKPSQSFP 807

Query: 476 GTGQLQEQKKGLLIAVSVSVDKIISHFG 503
            TG+         I    S  KIISH G
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPG 835


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 40/144 (27%), Positives = 53/144 (36%), Gaps = 17/144 (11%)

Query: 304 SEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSP--GGS 361
           S +P P       + L++ R+          +K   S      SP+    PS +P  GG 
Sbjct: 141 SSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS------SPEPWARPSCTPQEGGC 194

Query: 362 ------SAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRP 415
                  +PP       +L   + +P PP PP  PP   A V P PP PP PPR      
Sbjct: 195 PRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLS 254

Query: 416 GLQP---IAEGQSEEGRAVSPAAG 436
              P       Q E   A+   AG
Sbjct: 255 ASDPSLDFLRAQQETANAIRELAG 278



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 42/162 (25%), Positives = 56/162 (34%), Gaps = 19/162 (11%)

Query: 62  ANSNSPAVPCRCCQEHGPGLENRQD-----PSQEEEGAASPSD---PGCSSSLSSCSDLS 113
           A S+ P  P  C Q +    + R+D      +  + G++SP     P C+     C    
Sbjct: 139 APSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPK 198

Query: 114 PDESPVSVYLRDLPGDEDA-HPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASS 172
             ESP    L+ +     A  P P   PL    PLA   P   SP      P       S
Sbjct: 199 ERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPP----PPPRPPPTLS 254

Query: 173 SPDPGLD------SNCNALTTCQDVPSPGLEEEDERAEQDLP 208
           + DP LD         NA+         GL +  E     LP
Sbjct: 255 ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLP 296



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 383 PPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442
           PP+PP  PP       P PP P +PP   K     +P++   +    AV  A G      
Sbjct: 308 PPLPPPPPP-------PPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR 360

Query: 443 KEPGA 447
            E GA
Sbjct: 361 SEEGA 365



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 17/49 (34%), Positives = 21/49 (42%)

Query: 395 ALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAK 443
           +L PP PPPPP PP  +   P   P  E   E    V+        AA+
Sbjct: 305 SLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 4/56 (7%)

Query: 744 RALCDHTAARPDQLSFRRGEVLRVITTVD----EDWLRCGRDGMEGLVPVGYTSLV 795
           RAL D+TA  P +LSFRRG+VLRV+        + W  C   G +G+VP     L+
Sbjct: 11  RALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL 66



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 38/156 (24%), Positives = 54/156 (34%), Gaps = 12/156 (7%)

Query: 302 DVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGS 361
           DV   P P   +    E    R+ GP +   P   K  S  L ++    EL   G  GG+
Sbjct: 189 DVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGT 248

Query: 362 SAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIA 421
                +V         S  P   +   D      L+   PPPP        +RP L P A
Sbjct: 249 DEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPP--------HRPRL-PSA 299

Query: 422 EGQSEEGRAVSPAAGEEAPA---AKEPGAQAGLEVR 454
           E  S       P     +P+   +  PG +  ++ R
Sbjct: 300 ESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDR 335


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 41/156 (26%), Positives = 54/156 (34%), Gaps = 15/156 (9%)

Query: 303 VSEEPVPHRTITSFHELAQKRKRGP----GLPLVPQAKKDRSDWLIVFSPDTELPPSGSP 358
           +S+  +  R  T   +++ + K GP         PQ  + R  +          P    P
Sbjct: 164 LSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223

Query: 359 GGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPP---------RPPPPPVPPR 409
           GG   PP         R     P PP PP  PP G  L PP         RPPPP + P 
Sbjct: 224 GGP--PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG 281

Query: 410 RKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEP 445
           +   +P L P+  G         P  G   P    P
Sbjct: 282 QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 20/54 (37%), Positives = 22/54 (40%)

Query: 381 PAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPA 434
           P PP P + PP      PPRPP P  PP      P L     G       V+PA
Sbjct: 307 PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360



 Score = 33.5 bits (75), Expect = 0.80
 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 14/74 (18%)

Query: 348 PDTELPP--SGSPGGSSAPPREVTTFKE------LRSRSRAPAPPVPPRDPPVGWALVPP 399
           P   LPP  +G P     PP  V    +      L      P PPVP   PP G    PP
Sbjct: 255 PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG--PPPP 312

Query: 400 R----PPPPPVPPR 409
           +    PPP P PPR
Sbjct: 313 QQGPPPPPGPFPPR 326


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 17/174 (9%)

Query: 323  RKRGPGLPLVPQAKKDRSDWLIVFSPDTELP-------PSGSPGGSSAPPREVTTFKELR 375
            + RG G     +AK DR+  L   +P  E+P       PS +PG   +PP  V   K  +
Sbjct: 2328 KARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVD--KRAK 2385

Query: 376  SRSRAPAPPVPPRDPPVGWALVPPRP-PPPPVPPRRKKNRPGL-QPIAEGQSEEGRAVSP 433
            +    PAPP P   PP   +   P P    P P       P +  P    + ++ RA   
Sbjct: 2386 APKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEE 2445

Query: 434  AAGEEAPAAKEPGAQAGLEVRSSWSFAGVP---GAQRLWMAEAQSGTGQLQEQK 484
            +    A   + PG +A L V+        P    A+   +     G G  QE K
Sbjct: 2446 SG---AKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 94/451 (20%), Positives = 156/451 (34%), Gaps = 54/451 (11%)

Query: 34   EGPLSTPPPPGDTGGKESRGPCSGTLVDANSNSPAV---PCRCCQEHGPGLENRQDPSQE 90
            + P + P PP  +    +   C      A   +PA    P           + ++  + E
Sbjct: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444

Query: 91   EEGAASPSDPGCSSSLSSCSDLSPDESPVS------VYLRDLPGDEDAHPQPSIIPLEQG 144
            E GA  P  PG  + L    D     SP S      + LR+ PG        S++ L   
Sbjct: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504

Query: 145  SPLASAGPGTCSPDSFCCSPDSCSG-ASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERA 203
             P A    G+  P +    P +  G  +  P PGL        T +D  +P   ++ + A
Sbjct: 2505 PPAA----GSSEPKAPW--PKATDGDLAQEPGPGL--------TFEDSGNPKSPDKAQ-A 2549

Query: 204  EQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGNVN 263
            EQD        A++ +  +  +  S   +        +T+ E +  +N + G    G  N
Sbjct: 2550 EQD-------GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR-N 2601

Query: 264  SSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKR 323
             S  S      +   +++  + S S + +        S  S       + +S    +   
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661

Query: 324  KRGPGLPLVPQAKKDRSDWLIVFSPDTELP-PSGSPGGSSAPPREVTTFKELRSRSRAPA 382
                         +D S      S D   P P+  P   +A P + T     ++    P+
Sbjct: 2662 SSSSSSSSSSTTDEDSS----CSSDDEAAPAPTAGPSAQAALPTKATK----QAGKARPS 2713

Query: 383  PPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442
               P +  P   A  P  PPP P  P + K + G +  +  +  EG  + P   E A   
Sbjct: 2714 AHSPGKKTP---APQPQAPPPQPTQPLQPKAQAGAK--SRPKKREGVHL-PTTKELAKRQ 2767

Query: 443  KEPGAQ------AGLEVRSSWSFAGVPGAQR 467
            + P  +      A L  R  W + G P  +R
Sbjct: 2768 RLPSVENRPKIAAFLPARQLWKWFGKPTQRR 2798



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 15/205 (7%)

Query: 30   PELQEGPLSTPPPPG----DTGGKES--RGPCSGTLVDANSNSPAVPCRCCQEHGPGLEN 83
            P+  +G L+  P PG    D+G  +S  +        + + +S +              +
Sbjct: 2518 PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577

Query: 84   RQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQ 143
              +   EEEG  +  D GC +   +CS  S   +         P    +    S      
Sbjct: 2578 GSETEGEEEGDKN-GDGGCGTGGRNCSAASSRAAS--------PASSSSSSSSSSSSSSS 2628

Query: 144  GSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERA 203
             S  +S+   + S  S   S  S S +SSS      S+ ++ +T  +  S   ++E   A
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPA 2688

Query: 204  EQDLPTSELLEADDGKIDAGKTEPS 228
                P+++          AGK  PS
Sbjct: 2689 PTAGPSAQAALPTKATKQAGKARPS 2713



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 28/116 (24%)

Query: 378 SRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPA--- 434
           S  P PP PP+ PP          PP   P        G+  +   Q  E R V+P    
Sbjct: 333 SPLPPPPAPPKGPPA---------PPAATP-------AGVYTVFREQGREHRVVAPTFVP 376

Query: 435 ---AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGL 487
              A +E P   +  +QA  + R+    AG PG     + +A  G+ +  ++ +GL
Sbjct: 377 SVEAFDERPGPIQIASQA-RDARAREREAGRPG-----VLQAPPGSPRPLDRPEGL 426


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 706 PPTVSVLA---LVKRGAPPEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRG 762
           PP+ S L    L   GA  E     E+ A    +     AV     +T     +LSFRRG
Sbjct: 712 PPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVACFA-YTGRTAQELSFRRG 770

Query: 763 EVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
           +VLR+      DW R   +GM GL+P  Y +L
Sbjct: 771 DVLRLHERASSDWWRGEHNGMRGLIPHKYITL 802


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 40/147 (27%), Positives = 53/147 (36%), Gaps = 19/147 (12%)

Query: 305 EEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGSSAP 364
           ++P P    +S   +AQ     PG+   P A            P +  PP   PG +  P
Sbjct: 97  QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP---ATPPTSGAPPGSGPGPTPTP 153

Query: 365 PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQ 424
           P  VT+         AP    PP  P  G    PP+   PP PP      PG  P     
Sbjct: 154 PPAVTS---------APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG-PGPGP----- 198

Query: 425 SEEGRAVSPAAGEEAPAAKEPGAQAGL 451
            ++G       G + P   +PG   GL
Sbjct: 199 -KQGPGPGGPKGGKMPGGPKPGGGPGL 224



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 354 PSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKN 413
           P G   G S P   +      + + + P    PP+ PP      P +PPP P P ++++ 
Sbjct: 46  PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP------PHQPPPHPQPHQQQQP 99

Query: 414 RPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442
            P  Q  ++    +G   +P  G   PA+
Sbjct: 100 PPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 36/143 (25%), Positives = 44/143 (30%), Gaps = 18/143 (12%)

Query: 326 GPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSP-------GGSSAPPREVTTFKELRSRS 378
           GP  P+ P     +        P  + PP   P            PP    + K + ++ 
Sbjct: 55  GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114

Query: 379 RAPAPPV----------PPRDPPVGWALVPPRPPPPPVPPRRKKNR-PGLQPIAEGQSEE 427
             PAP V          PP  PP   A     P P P PP    +  PG  P     S  
Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174

Query: 428 GRAVSPAAGEEAPAAKEPGAQAG 450
                 A G   P A  PG   G
Sbjct: 175 PTTPPQAGGPPPPPAAVPGPGPG 197



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 18/91 (19%)

Query: 375 RSRSRAPAPPVPP----RDPPVGWALVPPRPPPPPVPPRRKKNRPGLQP----------- 419
           +S  + P PP PP    + PP      PP+ PPP  PP   +     QP           
Sbjct: 53  QSGPKPPIPPPPPHQQQQQPPPQQP--PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV 110

Query: 420 IAEGQS-EEGRAVSPAAGEEAPAAKEPGAQA 449
           +A+G     G   +P A   AP A  P + A
Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141


>gi|19913396 smoothelin isoform b [Homo sapiens]
          Length = 915

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 18/108 (16%)

Query: 354 PSGSPGGSS-----------APPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL---VPP 399
           P+ +P G+S           APP   ++     S S  PA P PP +P     L   VP 
Sbjct: 173 PTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPG 232

Query: 400 RPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP--AAGEEAPAAKEP 445
            P PPP PP+     P   P     S EG+ V+   +  +E PAA+ P
Sbjct: 233 SPEPPPSPPKTTSPEPQESPTL--PSTEGQVVNKLLSGPKETPAAQSP 278


>gi|19913394 smoothelin isoform c [Homo sapiens]
          Length = 917

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 18/108 (16%)

Query: 354 PSGSPGGSS-----------APPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL---VPP 399
           P+ +P G+S           APP   ++     S S  PA P PP +P     L   VP 
Sbjct: 173 PTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPG 232

Query: 400 RPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP--AAGEEAPAAKEP 445
            P PPP PP+     P   P     S EG+ V+   +  +E PAA+ P
Sbjct: 233 SPEPPPSPPKTTSPEPQESPTL--PSTEGQVVNKLLSGPKETPAAQSP 278


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.131    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,173,255
Number of Sequences: 37866
Number of extensions: 2748123
Number of successful extensions: 25576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 394
Number of HSP's successfully gapped in prelim test: 1130
Number of HSP's that attempted gapping in prelim test: 14144
Number of HSP's gapped (non-prelim): 7772
length of query: 796
length of database: 18,247,518
effective HSP length: 110
effective length of query: 686
effective length of database: 14,082,258
effective search space: 9660428988
effective search space used: 9660428988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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