BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sapiens] (796 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sap... 1640 0.0 gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 1280 0.0 gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 367 e-101 gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 367 e-101 gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] 149 1e-35 gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] 149 1e-35 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 53 1e-06 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06 gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens] 52 2e-06 gi|239741753 PREDICTED: hypothetical protein [Homo sapiens] 50 8e-06 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 50 1e-05 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 50 1e-05 gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 49 2e-05 gi|210032580 SET domain containing 1B [Homo sapiens] 48 3e-05 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 48 4e-05 gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 48 4e-05 gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 48 4e-05 gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ... 48 4e-05 gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 48 4e-05 gi|150170670 piccolo isoform 2 [Homo sapiens] 48 4e-05 gi|150378539 piccolo isoform 1 [Homo sapiens] 48 4e-05 gi|60460889 Myb protein P42POP [Homo sapiens] 47 5e-05 gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 47 7e-05 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 47 9e-05 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 47 9e-05 gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 47 9e-05 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 47 9e-05 gi|19913396 smoothelin isoform b [Homo sapiens] 47 9e-05 gi|19913394 smoothelin isoform c [Homo sapiens] 47 9e-05 >gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sapiens] Length = 796 Score = 1640 bits (4247), Expect = 0.0 Identities = 796/796 (100%), Positives = 796/796 (100%) Query: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV Sbjct: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60 Query: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS Sbjct: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120 Query: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS Sbjct: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180 Query: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE Sbjct: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240 Query: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR Sbjct: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300 Query: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG Sbjct: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360 Query: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI Sbjct: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420 Query: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL Sbjct: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480 Query: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA Sbjct: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540 Query: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI Sbjct: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600 Query: 601 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA 660 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA Sbjct: 601 LGLLNTKQLELWFSSLQEDAGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGA 660 Query: 661 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP 720 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP Sbjct: 661 QERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAP 720 Query: 721 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR 780 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR Sbjct: 721 PEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGR 780 Query: 781 DGMEGLVPVGYTSLVL 796 DGMEGLVPVGYTSLVL Sbjct: 781 DGMEGLVPVGYTSLVL 796 >gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sapiens] Length = 902 Score = 1280 bits (3312), Expect = 0.0 Identities = 621/621 (100%), Positives = 621/621 (100%) Query: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV Sbjct: 1 MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV 60 Query: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS Sbjct: 61 DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS 120 Query: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS Sbjct: 121 VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS 180 Query: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE Sbjct: 181 NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE 240 Query: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR Sbjct: 241 KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR 300 Query: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG Sbjct: 301 SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG 360 Query: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI Sbjct: 361 SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI 420 Query: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL Sbjct: 421 AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL 480 Query: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA Sbjct: 481 QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA 540 Query: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI Sbjct: 541 DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI 600 Query: 601 LGLLNTKQLELWFSSLQEDAG 621 LGLLNTKQLELWFSSLQEDAG Sbjct: 601 LGLLNTKQLELWFSSLQEDAG 621 Score = 367 bits (941), Expect = e-101 Identities = 176/176 (100%), Positives = 176/176 (100%) Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR Sbjct: 727 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 786 Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH Sbjct: 787 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 846 Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL Sbjct: 847 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 902 Score = 30.8 bits (68), Expect = 5.2 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%) Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454 L PP+ P PP PP P LQ + GR G AA +P L Sbjct: 673 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 726 Query: 455 SSW 457 SW Sbjct: 727 GSW 729 >gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sapiens] Length = 492 Score = 367 bits (941), Expect = e-101 Identities = 176/176 (100%), Positives = 176/176 (100%) Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR Sbjct: 317 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 376 Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH Sbjct: 377 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 436 Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL Sbjct: 437 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 492 Score = 336 bits (862), Expect = 4e-92 Identities = 175/189 (92%), Positives = 177/189 (93%), Gaps = 2/189 (1%) Query: 433 PAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS 492 P +PA + QAG VRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS Sbjct: 25 PPRAPSSPALQALAGQAG--VRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVS 82 Query: 493 VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT 552 VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT Sbjct: 83 VSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLIT 142 Query: 553 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW 612 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW Sbjct: 143 GQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELW 202 Query: 613 FSSLQEDAG 621 FSSLQEDAG Sbjct: 203 FSSLQEDAG 211 Score = 30.8 bits (68), Expect = 5.2 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%) Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454 L PP+ P PP PP P LQ + GR G AA +P L Sbjct: 263 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 316 Query: 455 SSW 457 SW Sbjct: 317 GSW 319 >gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapiens] Length = 433 Score = 367 bits (941), Expect = e-101 Identities = 176/176 (100%), Positives = 176/176 (100%) Query: 621 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 680 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR Sbjct: 258 GSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGR 317 Query: 681 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 740 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH Sbjct: 318 LFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTH 377 Query: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 796 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL Sbjct: 378 RAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL 433 Score = 295 bits (754), Expect = 1e-79 Identities = 152/152 (100%), Positives = 152/152 (100%) Query: 470 MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT 529 MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT Sbjct: 1 MAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLT 60 Query: 530 TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL 589 TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL Sbjct: 61 TLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPL 120 Query: 590 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG 621 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG Sbjct: 121 SSSRSRFHAFILGLLNTKQLELWFSSLQEDAG 152 Score = 30.8 bits (68), Expect = 5.2 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 7/63 (11%) Query: 396 LVPPRPPPPPVPPRRKKNRPGLQPIAEGQSE-EGRAVSPAAGEEAPAAKEPGAQAGLEVR 454 L PP+ P PP PP P LQ + GR G AA +P L Sbjct: 204 LGPPQAPAPPGPP------PALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTP 257 Query: 455 SSW 457 SW Sbjct: 258 GSW 260 >gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] Length = 1516 Score = 149 bits (376), Expect = 1e-35 Identities = 75/134 (55%), Positives = 102/134 (76%) Query: 483 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542 QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG Sbjct: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051 Query: 543 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602 LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG Sbjct: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111 Query: 603 LLNTKQLELWFSSL 616 LLN + LE WF+ L Sbjct: 1112 LLNIRSLEFWFNHL 1125 Score = 84.7 bits (208), Expect = 3e-16 Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%) Query: 623 WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661 WW QL Q+S+VY G EG SR+ G +++E EGA+ Sbjct: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326 Query: 662 ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697 P + + RG W+G G PAENE GA + Sbjct: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386 Query: 698 ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737 +R PS WL S+ LV + G+ E P P+E E +P + Sbjct: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445 Query: 738 QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794 + V+ALC H A P QLSF +G++LRV+ DWLRC R GLVP+ Y +L Sbjct: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503 >gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] Length = 1516 Score = 149 bits (376), Expect = 1e-35 Identities = 75/134 (55%), Positives = 102/134 (76%) Query: 483 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542 QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG Sbjct: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051 Query: 543 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602 LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG Sbjct: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111 Query: 603 LLNTKQLELWFSSL 616 LLN + LE WF+ L Sbjct: 1112 LLNIRSLEFWFNHL 1125 Score = 84.7 bits (208), Expect = 3e-16 Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%) Query: 623 WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661 WW QL Q+S+VY G EG SR+ G +++E EGA+ Sbjct: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326 Query: 662 ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697 P + + RG W+G G PAENE GA + Sbjct: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386 Query: 698 ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737 +R PS WL S+ LV + G+ E P P+E E +P + Sbjct: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445 Query: 738 QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794 + V+ALC H A P QLSF +G++LRV+ DWLRC R GLVP+ Y +L Sbjct: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 52.8 bits (125), Expect = 1e-06 Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%) Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251 + E+ + ++ P++ ++D K + + K +P+ ++ K T E Sbjct: 48 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107 Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311 + T K S + P + + + + D GS +D ID RS P P Sbjct: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 166 Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369 + AQ++ P + QA + P T +LP P +P ++ PP+ Sbjct: 167 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 225 Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426 T + ++ +AP PVP AL P RPP P PP + P LQP+ + GQ S Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 284 Query: 427 EGRAVSPAAGEEAP 440 A P G+ P Sbjct: 285 PSHAQPPLHGQGPP 298 Score = 36.6 bits (83), Expect = 0.094 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405 P T PP+G PG S+ PP + + S P P V ++ + A P PPPPP Sbjct: 499 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557 Query: 406 VPP 408 P Sbjct: 558 RSP 560 Score = 32.7 bits (73), Expect = 1.4 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%) Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402 P +L P P SS A P +T + L PP P PP G V P+PP Sbjct: 432 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 483 Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440 PPP+ P + PG QP G + G ++ A G P Sbjct: 484 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 533 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 52.8 bits (125), Expect = 1e-06 Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%) Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251 + E+ + ++ P++ ++D K + + K +P+ ++ K T E Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661 Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311 + T K S + P + + + + D GS +D ID RS P P Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 720 Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369 + AQ++ P + QA + P T +LP P +P ++ PP+ Sbjct: 721 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779 Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426 T + ++ +AP PVP AL P RPP P PP + P LQP+ + GQ S Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 838 Query: 427 EGRAVSPAAGEEAP 440 A P G+ P Sbjct: 839 PSHAQPPLHGQGPP 852 Score = 36.6 bits (83), Expect = 0.094 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405 P T PP+G PG S+ PP + + S P P V ++ + A P PPPPP Sbjct: 1053 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111 Query: 406 VPP 408 P Sbjct: 1112 RSP 1114 Score = 32.7 bits (73), Expect = 1.4 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%) Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402 P +L P P SS A P +T + L PP P PP G V P+PP Sbjct: 986 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 1037 Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440 PPP+ P + PG QP G + G ++ A G P Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 1087 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 52.8 bits (125), Expect = 1e-06 Identities = 62/254 (24%), Positives = 102/254 (40%), Gaps = 12/254 (4%) Query: 196 LEEEDERAEQDLPTSELLEADDGKID----AGKTEPSWKINPIWKIDTEKTKAEWKTTEN 251 + E+ + ++ P++ ++D K + + K +P+ ++ K T E Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661 Query: 252 NNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHR 311 + T K S + P + + + + D GS +D ID RS P P Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQD 720 Query: 312 TITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDT-ELP-PSGSPGGSSAPPREVT 369 + AQ++ P + QA + P T +LP P +P ++ PP+ Sbjct: 721 NESDSDSSAQQQMLQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779 Query: 370 TFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI--AEGQ-SE 426 T + ++ +AP PVP AL P RPP P PP + P LQP+ + GQ S Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSA 838 Query: 427 EGRAVSPAAGEEAP 440 A P G+ P Sbjct: 839 PSHAQPPLHGQGPP 852 Score = 36.6 bits (83), Expect = 0.094 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 348 PDTELPPSGSPGGSSAPPRE--VTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPP 405 P T PP+G PG S+ PP + + S P P V ++ + A P PPPPP Sbjct: 1053 PSTSTPPAG-PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111 Query: 406 VPP 408 P Sbjct: 1112 RSP 1114 Score = 32.7 bits (73), Expect = 1.4 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 29/112 (25%) Query: 348 PDTELPPSGSPGGSS-APPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPP---- 402 P +L P P SS A P +T + L PP P PP G V P+PP Sbjct: 986 PPLQLMPQSQPLPSSPAQPPGLTQSQNL--------PPPPASHPPTGLHQVAPQPPFAQH 1037 Query: 403 ------PPPVPPRRKKNR------PG--LQPIAEGQSEEGRAVSPAAGEEAP 440 PPP+ P + PG QP G + G ++ A G P Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI--AGGSSCP 1087 >gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens] Length = 1015 Score = 52.0 bits (123), Expect = 2e-06 Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 32/213 (15%) Query: 39 TPPPPGDTGGKESRGPCSGTLVDANSNS-PAVPCRCCQEHGPGLEN---------RQDPS 88 +PPP G + G C+G L+ ++ A P EHG G E D Sbjct: 192 SPPPAGSQRTQAGSGHCAGGLLGHEKHAMDASPT----EHGVGQEEDGPEDASPTEHDVG 247 Query: 89 QEEEGA--ASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQGSP 146 QEE+G ASP++ G D SP E V + G EDA P + E+ P Sbjct: 248 QEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVD---QQEDGPEDARPTEHGVDQEEDGP 304 Query: 147 LASA-----------GPGTCSPDSFCCSPDSCSGASSSP-DPGLDSNCNALTTCQDVPSP 194 ++ GP SP + +SP + G+D + Sbjct: 305 EDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHE 364 Query: 195 -GLEEEDERAEQDLPTSELLEADDGKIDAGKTE 226 G+++E++ E PT ++ +DG DA TE Sbjct: 365 HGVDQEEDGPEDASPTEHGVDQEDGPEDARPTE 397 >gi|239741753 PREDICTED: hypothetical protein [Homo sapiens] Length = 274 Score = 50.1 bits (118), Expect = 8e-06 Identities = 42/114 (36%), Positives = 49/114 (42%), Gaps = 23/114 (20%) Query: 358 PGGSSAPPREVTTFKELRSRSRAPAPPVPPRD------PPVGWALVPPRPPPPPVPPRRK 411 PGGS+ +E +E +R APP PPR PP+G L PRPPP PPR Sbjct: 71 PGGSADKDQE----REPSLAARGTAPPAPPRQCLPTPCPPLGHGL-RPRPPPGTPPPRCP 125 Query: 412 KNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAK------EPGAQAGLEVRSSWSF 459 + +A G A PA PA K PG AG VR S SF Sbjct: 126 RT------LAPGPRGLFPAPPPAPARTGPAGKAAADRGRPGPAAGRRVRRSPSF 173 Score = 33.5 bits (75), Expect = 0.80 Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 8/78 (10%) Query: 353 PPSGSPGGSSAPPREVTTFKELRSRSRAPA-PPVPPRDPPVGWALVPPRPPPPPVPPRRK 411 PP G+P PPR T R PA PP P R P G A R P P RR Sbjct: 115 PPPGTP-----PPRCPRTLAP-GPRGLFPAPPPAPARTGPAGKA-AADRGRPGPAAGRRV 167 Query: 412 KNRPGLQPIAEGQSEEGR 429 + P P Q+ GR Sbjct: 168 RRSPSFPPFLLAQTRLGR 185 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 49.7 bits (117), Expect = 1e-05 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%) Query: 685 PGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVR 744 PGG E E A +R W P + + L+ G P+ + + Q V Sbjct: 1108 PGGWWEGELQARGKKRQIGWFP--ANYVKLLSPGTSKITPTEPPKSTALAAVCQ----VI 1161 Query: 745 ALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794 + D+TA D+L+F +G+++ V+ D DW + +G GL P Y L Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKL 1211 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 49.7 bits (117), Expect = 1e-05 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%) Query: 685 PGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVR 744 PGG E E A +R W P + + L+ G P+ + + Q V Sbjct: 1108 PGGWWEGELQARGKKRQIGWFP--ANYVKLLSPGTSKITPTEPPKSTALAAVCQ----VI 1161 Query: 745 ALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794 + D+TA D+L+F +G+++ V+ D DW + +G GL P Y L Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKL 1211 >gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] Length = 547 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 9/84 (10%) Query: 354 PSGSPGGSSAPPREVTTFKELRSRSRAPA------PPVPPRDPPVGWALVPPRPPPPPVP 407 P SP S P++V T +RSR +P PP PP PP L PP PPPPP Sbjct: 393 PRHSPWSSPKLPKKVQT---VRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPL 449 Query: 408 PRRKKNRPGLQPIAEGQSEEGRAV 431 P +K + + + Q RA+ Sbjct: 450 PEKKLITRNIAEVIKQQESAQRAL 473 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 48.1 bits (113), Expect = 3e-05 Identities = 43/147 (29%), Positives = 58/147 (39%), Gaps = 19/147 (12%) Query: 284 TDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWL 343 T + K D G+ G ++S++ +P ITS + + PG V Sbjct: 622 TPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA-DCPKPMVVTPGAAAVAAPS------- 673 Query: 344 IVFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL-VPPRP- 401 V +P LPP PG PP + P PP PP PP A+ VPP P Sbjct: 674 -VLAPTLPLPPP--PGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730 Query: 402 ------PPPPVPPRRKKNRPGLQPIAE 422 PPPP+ P PGL P+ + Sbjct: 731 PAPPGVPPPPILPPLPPFPPGLFPVMQ 757 Score = 37.7 bits (86), Expect = 0.042 Identities = 77/335 (22%), Positives = 117/335 (34%), Gaps = 90/335 (26%) Query: 198 EEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWK 257 +E E ++D SE E D+G D +T I T K +A Sbjct: 1072 DESENDDEDTALSEASEKDEGDSDEEETV---------SIVTSKAEA------------- 1109 Query: 258 NNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSD--VSEEPVPHRTITS 315 +SS SE +F+S +++ ++ + A + + + V+EE + Sbjct: 1110 ----TSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPED 1165 Query: 316 FHELAQKRKRGPGLPLVPQ--------------AKKDRSDWLI-------VFSPDTELPP 354 F + ++ PG P V A ++R L V P P Sbjct: 1166 FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREP 1225 Query: 355 SGSPGGSSA--------PPREVTTFKELRSRSRAP-----APPVPPRDPPVGWA--LVPP 399 PG S PP + + S RAP P PP P+ L PP Sbjct: 1226 PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP 1285 Query: 400 RPPPPPVPPRRKK----NRPGL--QPIAE-------------GQSEEGRAVSPAAGEEAP 440 RPP PP PP + + P + +P+AE +S+ V G E P Sbjct: 1286 RPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPP 1345 Query: 441 AAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475 + G +GL S S VPG+ + A + S Sbjct: 1346 LS---GGSSGL----SLSSPQVPGSPFSYPAPSPS 1373 Score = 35.0 bits (79), Expect = 0.27 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 11/51 (21%) Query: 361 SSAPPREVTTFKELRSRS-RAPAPPVPPRDPPVGWALVPPRPPPPPVPPRR 410 S+ PR VT + R+ AP PP+PP+ PP PPPPPV P + Sbjct: 1520 STHDPRTVTL--DFRNAGIPAPPPPLPPQPPPP--------PPPPPVEPTK 1560 Score = 33.9 bits (76), Expect = 0.61 Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 9/87 (10%) Query: 364 PPREVTTFKELRSRS-----RAPAPP-VPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGL 417 PP E T +R RAPAPP +PP +P A P PP P PP G Sbjct: 410 PPEEPTATAAFGARDSGEFRRAPAPPPLPPAEP---LAKEKPGTPPGPPPPDTNSMELGG 466 Query: 418 QPIAEGQSEEGRAVSPAAGEEAPAAKE 444 +P E + E +PA E Sbjct: 467 RPTFGWSPEPCDSPGTPTLESSPAGPE 493 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 47.8 bits (112), Expect = 4e-05 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 16/116 (13%) Query: 347 SPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPP 399 S +PP+G G PP + + + APPVPP PP G + PP Sbjct: 580 SETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP 639 Query: 400 RPPP-----PPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAG 450 PP PPVPP P + P + G P G+ P P +G Sbjct: 640 VPPTGDSGAPPVPPTGDSGAPPVPP----TGDSGAPPVPPTGDAGPPPVPPTGDSG 691 Score = 47.8 bits (112), Expect = 4e-05 Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 20/115 (17%) Query: 352 LPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPPRPP-- 402 +PP+G G PP + + + APPVPP PP G + PP PP Sbjct: 618 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 677 Query: 403 ---PPPVPPRRKKNRP--------GLQPIAEGQSEEGRAVSPAAGEEAPAAKEPG 446 PPPVPP P G P+ E V P AP G Sbjct: 678 DAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTG 732 Score = 44.3 bits (103), Expect = 5e-04 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 16/111 (14%) Query: 352 LPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRD-------PPVGWALVPPRPPP- 403 +PP+G G PP + + + APPVPP PP G + PP PP Sbjct: 596 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 655 Query: 404 ----PPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAG 450 PPVPP P + P + G P G+ P +G Sbjct: 656 DSGAPPVPPTGDSGAPPVPPTGDA----GPPPVPPTGDSGAPPVPPTGDSG 702 >gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo sapiens] Length = 218 Score = 47.8 bits (112), Expect = 4e-05 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%) Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404 ++SP LPP P PPR P PP PPR P L PPRPP P Sbjct: 21 LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60 Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435 P+PP R P +A+ + ++SP++ Sbjct: 61 PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91 >gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo sapiens] Length = 218 Score = 47.8 bits (112), Expect = 4e-05 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%) Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404 ++SP LPP P PPR P PP PPR P L PPRPP P Sbjct: 21 LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60 Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435 P+PP R P +A+ + ++SP++ Sbjct: 61 PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91 >gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo sapiens] Length = 218 Score = 47.8 bits (112), Expect = 4e-05 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 20/91 (21%) Query: 345 VFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPP 404 ++SP LPP P PPR P PP PPR P L PPRPP P Sbjct: 21 LWSPPPPLPPR-KPPRPPKPPR--------------PLPPNPPRPP-----LPPPRPPKP 60 Query: 405 PVPPRRKKNRPGLQPIAEGQSEEGRAVSPAA 435 P+PP R P +A+ + ++SP++ Sbjct: 61 PLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91 >gi|59853099 dynamin 1 isoform 1 [Homo sapiens] Length = 864 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Query: 354 PSG--SPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWA-LVPPRP--------P 402 P+G SP S P R R SR PAP PP +G A VP RP P Sbjct: 769 PAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGP 828 Query: 403 PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP 433 PP VP R + PG+ P GQ+ R SP Sbjct: 829 PPQVPSRPNRAPPGV-PSRSGQASPSRPESP 858 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 47.8 bits (112), Expect = 4e-05 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Query: 354 PSGSPGGSSAP--PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK 411 PSGSP SS P PR L ++ P PP PP PP PP PPPPP P Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPPPPPPPPLPPPT 2431 Query: 412 KNRPGLQP 419 +P + P Sbjct: 2432 SPKPTILP 2439 Score = 34.7 bits (78), Expect = 0.36 Identities = 83/371 (22%), Positives = 125/371 (33%), Gaps = 71/371 (19%) Query: 147 LASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDV-----PSPGLEEEDE 201 L P T S D SS PG S NAL+ V P + + + Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184 Query: 202 RAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGN 261 E+ ++++ + GK P I P + + K K + +G Sbjct: 185 SQEETTKKQKVVQKEQGK-------PEGIIKP--PLQQQPPKPIPKQQGPGRDPLQQDGT 235 Query: 262 VNSSWKSEPEKFDS---GWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHE 318 S +PEK S G + +TD K+ + D S I Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP--LQRDASRPQTKQADIV---- 289 Query: 319 LAQKRKRGPGL-PLVPQAKKDRSDWLIVFSPDTELPPSGSPG------GSSAPPREVTTF 371 RG + P +P K + P PP+ PG G + PP + + Sbjct: 290 ------RGESVKPSLPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338 Query: 372 KELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK-------KNRPG----LQPI 420 + ++ P PP PP G P +P P PP ++ +PG QP Sbjct: 339 T--KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395 Query: 421 AEGQS---EEGRAVSPA--AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475 G++ + G A P G P A++PG Q S A PG + Q Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ---------SPAKAPGPTK--TPVQQP 444 Query: 476 GTGQLQEQKKG 486 G G++ Q+ G Sbjct: 445 GPGKIPAQQAG 455 Score = 32.7 bits (73), Expect = 1.4 Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 31/170 (18%) Query: 348 PDTELPPSGSPGGSSAPPREVTTFKEL------RSRSRAPAPPVPPRDPPVGWALV---- 397 P P+ PG + P ++V T K L +S ++AP P P P + Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454 Query: 398 -----------PPRPP--------PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEE 438 P +PP PPP P K P A+ S++ + P + Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514 Query: 439 APAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAE--AQSGTGQLQEQKKG 486 PA P + S + P AQ+ A+ AQ T + + G Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564 Score = 30.4 bits (67), Expect = 6.7 Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 41/208 (19%) Query: 322 KRKRGPGLPLVPQAKKDRSDWLIV-----FSPDTELPPSGSPGGSSAPPREVTTFKELRS 376 KR G L VP + + + V S + P SP +AP +++ Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-------- 694 Query: 377 RSRAPAPPVPP----------------RDPPVGWALVPPRPP-PPPVPPRRKKNRPGLQP 419 S+AP P PP + PP +L P PP P VP + K P Sbjct: 695 -SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK-----AP 748 Query: 420 IAEGQSEEGRAVSPAAG--EEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS-- 475 +A+ + ++ + V P + A +P + +V+S P + +QS Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAKPSQSFP 807 Query: 476 GTGQLQEQKKGLLIAVSVSVDKIISHFG 503 TG+ I S KIISH G Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPG 835 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 47.8 bits (112), Expect = 4e-05 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Query: 354 PSGSPGGSSAP--PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK 411 PSGSP SS P PR L ++ P PP PP PP PP PPPPP P Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPPPPPPPPLPPPT 2431 Query: 412 KNRPGLQP 419 +P + P Sbjct: 2432 SPKPTILP 2439 Score = 34.7 bits (78), Expect = 0.36 Identities = 83/371 (22%), Positives = 125/371 (33%), Gaps = 71/371 (19%) Query: 147 LASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDV-----PSPGLEEEDE 201 L P T S D SS PG S NAL+ V P + + + Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184 Query: 202 RAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGN 261 E+ ++++ + GK P I P + + K K + +G Sbjct: 185 SQEETTKKQKVVQKEQGK-------PEGIIKP--PLQQQPPKPIPKQQGPGRDPLQQDGT 235 Query: 262 VNSSWKSEPEKFDS---GWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHE 318 S +PEK S G + +TD K+ + D S I Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP--LQRDASRPQTKQADIV---- 289 Query: 319 LAQKRKRGPGL-PLVPQAKKDRSDWLIVFSPDTELPPSGSPG------GSSAPPREVTTF 371 RG + P +P K + P PP+ PG G + PP + + Sbjct: 290 ------RGESVKPSLPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338 Query: 372 KELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRK-------KNRPG----LQPI 420 + ++ P PP PP G P +P P PP ++ +PG QP Sbjct: 339 T--KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395 Query: 421 AEGQS---EEGRAVSPA--AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS 475 G++ + G A P G P A++PG Q S A PG + Q Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ---------SPAKAPGPTK--TPVQQP 444 Query: 476 GTGQLQEQKKG 486 G G++ Q+ G Sbjct: 445 GPGKIPAQQAG 455 Score = 32.7 bits (73), Expect = 1.4 Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 31/170 (18%) Query: 348 PDTELPPSGSPGGSSAPPREVTTFKEL------RSRSRAPAPPVPPRDPPVGWALV---- 397 P P+ PG + P ++V T K L +S ++AP P P P + Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454 Query: 398 -----------PPRPP--------PPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEE 438 P +PP PPP P K P A+ S++ + P + Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514 Query: 439 APAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAE--AQSGTGQLQEQKKG 486 PA P + S + P AQ+ A+ AQ T + + G Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564 Score = 30.4 bits (67), Expect = 6.7 Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 41/208 (19%) Query: 322 KRKRGPGLPLVPQAKKDRSDWLIV-----FSPDTELPPSGSPGGSSAPPREVTTFKELRS 376 KR G L VP + + + V S + P SP +AP +++ Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-------- 694 Query: 377 RSRAPAPPVPP----------------RDPPVGWALVPPRPP-PPPVPPRRKKNRPGLQP 419 S+AP P PP + PP +L P PP P VP + K P Sbjct: 695 -SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK-----AP 748 Query: 420 IAEGQSEEGRAVSPAAG--EEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQS-- 475 +A+ + ++ + V P + A +P + +V+S P + +QS Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAKPSQSFP 807 Query: 476 GTGQLQEQKKGLLIAVSVSVDKIISHFG 503 TG+ I S KIISH G Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPG 835 >gi|60460889 Myb protein P42POP [Homo sapiens] Length = 399 Score = 47.4 bits (111), Expect = 5e-05 Identities = 40/144 (27%), Positives = 53/144 (36%), Gaps = 17/144 (11%) Query: 304 SEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSP--GGS 361 S +P P + L++ R+ +K S SP+ PS +P GG Sbjct: 141 SSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS------SPEPWARPSCTPQEGGC 194 Query: 362 ------SAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRP 415 +PP +L + +P PP PP PP A V P PP PP PPR Sbjct: 195 PRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLS 254 Query: 416 GLQP---IAEGQSEEGRAVSPAAG 436 P Q E A+ AG Sbjct: 255 ASDPSLDFLRAQQETANAIRELAG 278 Score = 36.2 bits (82), Expect = 0.12 Identities = 42/162 (25%), Positives = 56/162 (34%), Gaps = 19/162 (11%) Query: 62 ANSNSPAVPCRCCQEHGPGLENRQD-----PSQEEEGAASPSD---PGCSSSLSSCSDLS 113 A S+ P P C Q + + R+D + + G++SP P C+ C Sbjct: 139 APSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPK 198 Query: 114 PDESPVSVYLRDLPGDEDA-HPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASS 172 ESP L+ + A P P PL PLA P SP P S Sbjct: 199 ERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPP----PPPRPPPTLS 254 Query: 173 SPDPGLD------SNCNALTTCQDVPSPGLEEEDERAEQDLP 208 + DP LD NA+ GL + E LP Sbjct: 255 ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLP 296 Score = 31.2 bits (69), Expect = 4.0 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 383 PPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442 PP+PP PP P PP P +PP K +P++ + AV A G Sbjct: 308 PPLPPPPPP-------PPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR 360 Query: 443 KEPGA 447 E GA Sbjct: 361 SEEGA 365 Score = 30.0 bits (66), Expect = 8.8 Identities = 17/49 (34%), Positives = 21/49 (42%) Query: 395 ALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAK 443 +L PP PPPPP PP + P P E E V+ AA+ Sbjct: 305 SLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353 >gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sapiens] Length = 561 Score = 47.0 bits (110), Expect = 7e-05 Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 4/56 (7%) Query: 744 RALCDHTAARPDQLSFRRGEVLRVITTVD----EDWLRCGRDGMEGLVPVGYTSLV 795 RAL D+TA P +LSFRRG+VLRV+ + W C G +G+VP L+ Sbjct: 11 RALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL 66 Score = 31.2 bits (69), Expect = 4.0 Identities = 38/156 (24%), Positives = 54/156 (34%), Gaps = 12/156 (7%) Query: 302 DVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGS 361 DV P P + E R+ GP + P K S L ++ EL G GG+ Sbjct: 189 DVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGT 248 Query: 362 SAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIA 421 +V S P + D L+ PPPP +RP L P A Sbjct: 249 DEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPP--------HRPRL-PSA 299 Query: 422 EGQSEEGRAVSPAAGEEAPA---AKEPGAQAGLEVR 454 E S P +P+ + PG + ++ R Sbjct: 300 ESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDR 335 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 46.6 bits (109), Expect = 9e-05 Identities = 41/156 (26%), Positives = 54/156 (34%), Gaps = 15/156 (9%) Query: 303 VSEEPVPHRTITSFHELAQKRKRGP----GLPLVPQAKKDRSDWLIVFSPDTELPPSGSP 358 +S+ + R T +++ + K GP PQ + R + P P Sbjct: 164 LSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223 Query: 359 GGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPP---------RPPPPPVPPR 409 GG PP R P PP PP PP G L PP RPPPP + P Sbjct: 224 GGP--PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG 281 Query: 410 RKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEP 445 + +P L P+ G P G P P Sbjct: 282 QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317 Score = 34.7 bits (78), Expect = 0.36 Identities = 20/54 (37%), Positives = 22/54 (40%) Query: 381 PAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPA 434 P PP P + PP PPRPP P PP P L G V+PA Sbjct: 307 PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360 Score = 33.5 bits (75), Expect = 0.80 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 14/74 (18%) Query: 348 PDTELPP--SGSPGGSSAPPREVTTFKE------LRSRSRAPAPPVPPRDPPVGWALVPP 399 P LPP +G P PP V + L P PPVP PP G PP Sbjct: 255 PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG--PPPP 312 Query: 400 R----PPPPPVPPR 409 + PPP P PPR Sbjct: 313 QQGPPPPPGPFPPR 326 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 46.6 bits (109), Expect = 9e-05 Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 17/174 (9%) Query: 323 RKRGPGLPLVPQAKKDRSDWLIVFSPDTELP-------PSGSPGGSSAPPREVTTFKELR 375 + RG G +AK DR+ L +P E+P PS +PG +PP V K + Sbjct: 2328 KARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVD--KRAK 2385 Query: 376 SRSRAPAPPVPPRDPPVGWALVPPRP-PPPPVPPRRKKNRPGL-QPIAEGQSEEGRAVSP 433 + PAPP P PP + P P P P P + P + ++ RA Sbjct: 2386 APKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEE 2445 Query: 434 AAGEEAPAAKEPGAQAGLEVRSSWSFAGVP---GAQRLWMAEAQSGTGQLQEQK 484 + A + PG +A L V+ P A+ + G G QE K Sbjct: 2446 SG---AKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496 Score = 39.3 bits (90), Expect = 0.015 Identities = 94/451 (20%), Positives = 156/451 (34%), Gaps = 54/451 (11%) Query: 34 EGPLSTPPPPGDTGGKESRGPCSGTLVDANSNSPAV---PCRCCQEHGPGLENRQDPSQE 90 + P + P PP + + C A +PA P + ++ + E Sbjct: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444 Query: 91 EEGAASPSDPGCSSSLSSCSDLSPDESPVS------VYLRDLPGDEDAHPQPSIIPLEQG 144 E GA P PG + L D SP S + LR+ PG S++ L Sbjct: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504 Query: 145 SPLASAGPGTCSPDSFCCSPDSCSG-ASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERA 203 P A G+ P + P + G + P PGL T +D +P ++ + A Sbjct: 2505 PPAA----GSSEPKAPW--PKATDGDLAQEPGPGL--------TFEDSGNPKSPDKAQ-A 2549 Query: 204 EQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGNVN 263 EQD A++ + + + S + +T+ E + +N + G G N Sbjct: 2550 EQD-------GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR-N 2601 Query: 264 SSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKR 323 S S + +++ + S S + + S S + +S + Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661 Query: 324 KRGPGLPLVPQAKKDRSDWLIVFSPDTELP-PSGSPGGSSAPPREVTTFKELRSRSRAPA 382 +D S S D P P+ P +A P + T ++ P+ Sbjct: 2662 SSSSSSSSSSTTDEDSS----CSSDDEAAPAPTAGPSAQAALPTKATK----QAGKARPS 2713 Query: 383 PPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442 P + P A P PPP P P + K + G + + + EG + P E A Sbjct: 2714 AHSPGKKTP---APQPQAPPPQPTQPLQPKAQAGAK--SRPKKREGVHL-PTTKELAKRQ 2767 Query: 443 KEPGAQ------AGLEVRSSWSFAGVPGAQR 467 + P + A L R W + G P +R Sbjct: 2768 RLPSVENRPKIAAFLPARQLWKWFGKPTQRR 2798 Score = 37.4 bits (85), Expect = 0.055 Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 15/205 (7%) Query: 30 PELQEGPLSTPPPPG----DTGGKES--RGPCSGTLVDANSNSPAVPCRCCQEHGPGLEN 83 P+ +G L+ P PG D+G +S + + + +S + + Sbjct: 2518 PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577 Query: 84 RQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQ 143 + EEEG + D GC + +CS S + P + S Sbjct: 2578 GSETEGEEEGDKN-GDGGCGTGGRNCSAASSRAAS--------PASSSSSSSSSSSSSSS 2628 Query: 144 GSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERA 203 S +S+ + S S S S S +SSS S+ ++ +T + S ++E A Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPA 2688 Query: 204 EQDLPTSELLEADDGKIDAGKTEPS 228 P+++ AGK PS Sbjct: 2689 PTAGPSAQAALPTKATKQAGKARPS 2713 Score = 31.2 bits (69), Expect = 4.0 Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 28/116 (24%) Query: 378 SRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPA--- 434 S P PP PP+ PP PP P G+ + Q E R V+P Sbjct: 333 SPLPPPPAPPKGPPA---------PPAATP-------AGVYTVFREQGREHRVVAPTFVP 376 Query: 435 ---AGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGL 487 A +E P + +QA + R+ AG PG + +A G+ + ++ +GL Sbjct: 377 SVEAFDERPGPIQIASQA-RDARAREREAGRPG-----VLQAPPGSPRPLDRPEGL 426 >gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] Length = 946 Score = 46.6 bits (109), Expect = 9e-05 Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 706 PPTVSVLA---LVKRGAPPEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRG 762 PP+ S L L GA E E+ A + AV +T +LSFRRG Sbjct: 712 PPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVACFA-YTGRTAQELSFRRG 770 Query: 763 EVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794 +VLR+ DW R +GM GL+P Y +L Sbjct: 771 DVLRLHERASSDWWRGEHNGMRGLIPHKYITL 802 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 46.6 bits (109), Expect = 9e-05 Identities = 40/147 (27%), Positives = 53/147 (36%), Gaps = 19/147 (12%) Query: 305 EEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGSSAP 364 ++P P +S +AQ PG+ P A P + PP PG + P Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP---ATPPTSGAPPGSGPGPTPTP 153 Query: 365 PREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQ 424 P VT+ AP PP P G PP+ PP PP PG P Sbjct: 154 PPAVTS---------APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG-PGPGP----- 198 Query: 425 SEEGRAVSPAAGEEAPAAKEPGAQAGL 451 ++G G + P +PG GL Sbjct: 199 -KQGPGPGGPKGGKMPGGPKPGGGPGL 224 Score = 39.3 bits (90), Expect = 0.015 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%) Query: 354 PSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKN 413 P G G S P + + + + P PP+ PP P +PPP P P ++++ Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP------PHQPPPHPQPHQQQQP 99 Query: 414 RPGLQPIAEGQSEEGRAVSPAAGEEAPAA 442 P Q ++ +G +P G PA+ Sbjct: 100 PPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128 Score = 35.4 bits (80), Expect = 0.21 Identities = 36/143 (25%), Positives = 44/143 (30%), Gaps = 18/143 (12%) Query: 326 GPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSP-------GGSSAPPREVTTFKELRSRS 378 GP P+ P + P + PP P PP + K + ++ Sbjct: 55 GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114 Query: 379 RAPAPPV----------PPRDPPVGWALVPPRPPPPPVPPRRKKNR-PGLQPIAEGQSEE 427 PAP V PP PP A P P P PP + PG P S Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174 Query: 428 GRAVSPAAGEEAPAAKEPGAQAG 450 A G P A PG G Sbjct: 175 PTTPPQAGGPPPPPAAVPGPGPG 197 Score = 32.7 bits (73), Expect = 1.4 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 18/91 (19%) Query: 375 RSRSRAPAPPVPP----RDPPVGWALVPPRPPPPPVPPRRKKNRPGLQP----------- 419 +S + P PP PP + PP PP+ PPP PP + QP Sbjct: 53 QSGPKPPIPPPPPHQQQQQPPPQQP--PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV 110 Query: 420 IAEGQS-EEGRAVSPAAGEEAPAAKEPGAQA 449 +A+G G +P A AP A P + A Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141 >gi|19913396 smoothelin isoform b [Homo sapiens] Length = 915 Score = 46.6 bits (109), Expect = 9e-05 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 18/108 (16%) Query: 354 PSGSPGGSS-----------APPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL---VPP 399 P+ +P G+S APP ++ S S PA P PP +P L VP Sbjct: 173 PTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPG 232 Query: 400 RPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP--AAGEEAPAAKEP 445 P PPP PP+ P P S EG+ V+ + +E PAA+ P Sbjct: 233 SPEPPPSPPKTTSPEPQESPTL--PSTEGQVVNKLLSGPKETPAAQSP 278 >gi|19913394 smoothelin isoform c [Homo sapiens] Length = 917 Score = 46.6 bits (109), Expect = 9e-05 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 18/108 (16%) Query: 354 PSGSPGGSS-----------APPREVTTFKELRSRSRAPAPPVPPRDPPVGWAL---VPP 399 P+ +P G+S APP ++ S S PA P PP +P L VP Sbjct: 173 PTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPG 232 Query: 400 RPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSP--AAGEEAPAAKEP 445 P PPP PP+ P P S EG+ V+ + +E PAA+ P Sbjct: 233 SPEPPPSPPKTTSPEPQESPTL--PSTEGQVVNKLLSGPKETPAAQSP 278 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.131 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,173,255 Number of Sequences: 37866 Number of extensions: 2748123 Number of successful extensions: 25576 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 394 Number of HSP's successfully gapped in prelim test: 1130 Number of HSP's that attempted gapping in prelim test: 14144 Number of HSP's gapped (non-prelim): 7772 length of query: 796 length of database: 18,247,518 effective HSP length: 110 effective length of query: 686 effective length of database: 14,082,258 effective search space: 9660428988 effective search space used: 9660428988 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.