Guide to the Human Genome
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Search of human proteins with 156766084

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156766084 transmembrane protein 16C [Homo sapiens]
         (981 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156766084 transmembrane protein 16C [Homo sapiens]                2028   0.0  
gi|218084958 anoctamin 4 [Homo sapiens]                              1235   0.0  
gi|218156303 anoctamin 6 isoform b [Homo sapiens]                     695   0.0  
gi|218156299 anoctamin 6 isoform a [Homo sapiens]                     695   0.0  
gi|47106048 anoctamin 5 isoform a [Homo sapiens]                      693   0.0  
gi|218081589 anoctamin 5 isoform b [Homo sapiens]                     692   0.0  
gi|218156307 anoctamin 6 isoform c [Homo sapiens]                     654   0.0  
gi|218156305 anoctamin 6 isoform c [Homo sapiens]                     654   0.0  
gi|209862785 anoctamin 2 [Homo sapiens]                               649   0.0  
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho...   639   0.0  
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s...   562   e-160
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]     525   e-149
gi|94536803 transmembrane protein 16K [Homo sapiens]                  178   2e-44
gi|55741655 anoctamin 8 [Homo sapiens]                                107   4e-23
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]            87   6e-17
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]            84   6e-16
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]            69   2e-11
gi|91982772 mucin 17 [Homo sapiens]                                    34   0.59 
gi|114842410 zinc finger CCCH-type containing 11A [Homo sapiens]       34   0.77 
gi|5729862 stem-loop (histone) binding protein [Homo sapiens]          32   3.8  
gi|148229509 G protein-coupled receptor 89A isoform 2 [Homo sapi...    31   5.0  
gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo sapi...    31   5.0  
gi|7706704 G protein-coupled receptor 89B [Homo sapiens]               31   5.0  
gi|148234741 G protein-coupled receptor 89C [Homo sapiens]             31   5.0  
gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]        31   6.5  
gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]        31   6.5  
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa...    30   8.5  
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot...    30   8.5  

>gi|156766084 transmembrane protein 16C [Homo sapiens]
          Length = 981

 Score = 2028 bits (5253), Expect = 0.0
 Identities = 981/981 (100%), Positives = 981/981 (100%)

Query: 1   MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST 60
           MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST
Sbjct: 1   MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST 60

Query: 61  ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT 120
           ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT
Sbjct: 61  ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT 120

Query: 121 YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR 180
           YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR
Sbjct: 121 YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR 180

Query: 181 NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR 240
           NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR
Sbjct: 181 NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR 240

Query: 241 SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF 300
           SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF
Sbjct: 241 SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF 300

Query: 301 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN 360
           SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN
Sbjct: 301 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN 360

Query: 361 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG 420
           NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG
Sbjct: 361 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG 420

Query: 421 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA 480
           LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA
Sbjct: 421 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA 480

Query: 481 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS 540
           IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS
Sbjct: 481 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS 540

Query: 541 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV 600
           SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV
Sbjct: 541 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV 600

Query: 601 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL 660
           CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL
Sbjct: 601 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL 660

Query: 661 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW 720
           GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW
Sbjct: 661 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW 720

Query: 721 SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL 780
           SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL
Sbjct: 721 SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL 780

Query: 781 LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR 840
           LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR
Sbjct: 781 LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR 840

Query: 841 FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY 900
           FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY
Sbjct: 841 FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY 900

Query: 901 EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA 960
           EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA
Sbjct: 901 EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA 960

Query: 961 ELEHLQQQRRKSGQPVHHEWP 981
           ELEHLQQQRRKSGQPVHHEWP
Sbjct: 961 ELEHLQQQRRKSGQPVHHEWP 981


>gi|218084958 anoctamin 4 [Homo sapiens]
          Length = 920

 Score = 1235 bits (3195), Expect = 0.0
 Identities = 580/849 (68%), Positives = 692/849 (81%), Gaps = 19/849 (2%)

Query: 152 SSGPLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIH 211
           S+G  F+DGK RIDYILVYRK+N Q +KR  FE+N+RAEGL +EKE ++ + DI+F+K+H
Sbjct: 72  SNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLH 131

Query: 212 IPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFP 271
            PW+ L +YAE++N+RMPFR+K YY   R K M R+     R + W+ + PM LDK   P
Sbjct: 132 APWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLP 191

Query: 272 DLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLI 331
           DLEE+DCYT PFS+ RIHHFII+NK+TFF+NATRSRIV+H+L+R KYE G +K+G+ +L+
Sbjct: 192 DLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLL 251

Query: 332 NNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEK 391
            NGSY AAFP HEG+Y+S   I+THG +N+RHLLYE WA WG+WYK+QPLDL+R YFGEK
Sbjct: 252 TNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEK 311

Query: 392 IGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSL 451
           IGLYFAWLGWYTGML PAA +GL VF YG+ T+++SQVS+E+C+AT++ MCP+CDK C  
Sbjct: 312 IGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPF 371

Query: 452 QRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEE 511
            RL+DSC+YAKVT+LFDNG TVFFA+FMA+WATVFLEFWKRRR+++ Y WDLI+WEEEEE
Sbjct: 372 MRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEE 431

Query: 512 TLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVY 571
            +RPQFEAKY K E +NPI+GKPEP+Q  +DK +RL+VS SGIFFMI +VI AVFG+V+Y
Sbjct: 432 EIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIY 491

Query: 572 RLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTES 631
           R+V +  FA+FKW  I+   Q AT+  AVCINF IIMLLN+ YEK+A LLTNLE PRTES
Sbjct: 492 RVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTES 551

Query: 632 EWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDL 691
           EWENSF LKMFLFQFVNLNSS FYIAFFLGRF GHPG Y +L +RWRLEECHPSGCLIDL
Sbjct: 552 EWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDL 611

Query: 692 CLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKR---GIHDASIPQWENDWNLQPMNL 748
           C+QMG+IM LKQ WNNFMELGYPLIQNWW+R K+++        S PQWE D+NLQPMN 
Sbjct: 612 CMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNA 671

Query: 749 HGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATD 808
           +GL DEYLEM+LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPL +RA D
Sbjct: 672 YGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKD 731

Query: 809 IGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNS 868
           IGIW GILEGIGIL+VITNAFVIAITSD+IPR VY YKYGPCA   E  + C+ GYVN S
Sbjct: 732 IGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNAS 791

Query: 869 LSFFDLSEL---------GMGKSG----YCRYRDYRGPPWSSKPYEFTLQYWHILAARLA 915
           LS F +S+          G   SG    YCRYRDYR PP S  PY +TLQ+WH+LAARLA
Sbjct: 792 LSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLA 851

Query: 916 FIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQ---QQRRKS 972
           FIIVFEHLVF IK  I+YLIPD+PK L DR+RREKYL+QEMMYEAELE LQ   ++R+K+
Sbjct: 852 FIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKN 911

Query: 973 GQPVHHEWP 981
           G+  H+EWP
Sbjct: 912 GKAHHNEWP 920


>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
          Length = 892

 Score =  695 bits (1794), Expect = 0.0
 Identities = 377/855 (44%), Positives = 536/855 (62%), Gaps = 63/855 (7%)

Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205
           F DG++RID++LVY     ++TN       Q  KR  +E NL   GL LE   ++    +
Sbjct: 44  FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 103

Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265
           +F+K+H PW+ LC YAE ++I++P +        RS + G +        NW  +   V 
Sbjct: 104 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 153

Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323
           +    P   E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+  N +S
Sbjct: 154 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 210

Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383
           K GI +L+N+G Y AAFP H+  ++     +     N R+LLY  WA     YK QPLDL
Sbjct: 211 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 268

Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440
           IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+  F YG    +N   S+E+C      ++ 
Sbjct: 269 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 328

Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500
           MCP CD+ C   +LN +C  +K   +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y 
Sbjct: 329 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 388

Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559
           WD +E ++EE+  RP++EA+   + ++N IT + E    ++  K  R+ +  S +FF I 
Sbjct: 389 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 446

Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611
           L+I +V G++VYRL V   F A    N      I++Y   Q ATS  A  I+FIIIM+LN
Sbjct: 447 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 506

Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671
             YEK+A ++TN E PRT++++ENS  +KMFLFQFVN  SS FYIAFF G+FVG+PG   
Sbjct: 507 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 566

Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730
               ++R EEC P GCL++L  Q+ +IM  K IWNN  E+  P I N   R H++     
Sbjct: 567 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 624

Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790
           +   P+WE D++LQPM   GL  EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D
Sbjct: 625 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 684

Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848
           A+K  TQ+RR +P +A DIG W  I++GI ILAV+TNA +IA TSD IPR VY + +   
Sbjct: 685 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 744

Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898
           P  +H   +   ++GY+NN+LS F +++            +G    CRYRD+R PP   +
Sbjct: 745 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 801

Query: 899 PYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMY 958
            Y+  + YWH++AA+LAFIIV EH+++ +K FI+Y IPDV K    +I+REKYL Q++++
Sbjct: 802 EYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLH 861

Query: 959 EAELEHLQQQRRKSG 973
           E    HL+   +  G
Sbjct: 862 E---NHLKDMTKNMG 873


>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
          Length = 910

 Score =  695 bits (1794), Expect = 0.0
 Identities = 377/855 (44%), Positives = 536/855 (62%), Gaps = 63/855 (7%)

Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205
           F DG++RID++LVY     ++TN       Q  KR  +E NL   GL LE   ++    +
Sbjct: 62  FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 121

Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265
           +F+K+H PW+ LC YAE ++I++P +        RS + G +        NW  +   V 
Sbjct: 122 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 171

Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323
           +    P   E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+  N +S
Sbjct: 172 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 228

Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383
           K GI +L+N+G Y AAFP H+  ++     +     N R+LLY  WA     YK QPLDL
Sbjct: 229 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 286

Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440
           IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+  F YG    +N   S+E+C      ++ 
Sbjct: 287 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 346

Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500
           MCP CD+ C   +LN +C  +K   +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y 
Sbjct: 347 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 406

Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559
           WD +E ++EE+  RP++EA+   + ++N IT + E    ++  K  R+ +  S +FF I 
Sbjct: 407 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 464

Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611
           L+I +V G++VYRL V   F A    N      I++Y   Q ATS  A  I+FIIIM+LN
Sbjct: 465 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 524

Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671
             YEK+A ++TN E PRT++++ENS  +KMFLFQFVN  SS FYIAFF G+FVG+PG   
Sbjct: 525 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 584

Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730
               ++R EEC P GCL++L  Q+ +IM  K IWNN  E+  P I N   R H++     
Sbjct: 585 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 642

Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790
           +   P+WE D++LQPM   GL  EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D
Sbjct: 643 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 702

Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848
           A+K  TQ+RR +P +A DIG W  I++GI ILAV+TNA +IA TSD IPR VY + +   
Sbjct: 703 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 762

Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898
           P  +H   +   ++GY+NN+LS F +++            +G    CRYRD+R PP   +
Sbjct: 763 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 819

Query: 899 PYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMY 958
            Y+  + YWH++AA+LAFIIV EH+++ +K FI+Y IPDV K    +I+REKYL Q++++
Sbjct: 820 EYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLH 879

Query: 959 EAELEHLQQQRRKSG 973
           E    HL+   +  G
Sbjct: 880 E---NHLKDMTKNMG 891


>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
          Length = 913

 Score =  693 bits (1788), Expect = 0.0
 Identities = 388/897 (43%), Positives = 549/897 (61%), Gaps = 62/897 (6%)

Query: 106 LGKDKDYT---DESEHATYDRSRLINDFVIKDKSEFKTKLSKNDM---NYIASSGPLFKD 159
           + K  DY+    E   ++ + S LIN+  +  K  F   L +  M   N  +     F+D
Sbjct: 17  VNKHIDYSFQMSEQSLSSRETSFLINEETMPAK-RFNLFLRRRLMFQKNQQSKDSIFFRD 75

Query: 160 GKKRIDYILVY-----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPD--IMFIKIHI 212
           G ++ID++L Y     +   ++ ++R  FE NLR  GL LE E    S D    F+KIH 
Sbjct: 76  GIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHA 135

Query: 213 PWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPD 272
           PW+ L  YAE L I+MP ++        +                    P+ L  S    
Sbjct: 136 PWEVLVTYAEVLGIKMPIKESDIPRPKHTPIS-------------YVLGPVRLPLSV--K 180

Query: 273 LEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKY--ENGISKVGIRKL 330
               + +T  FSR R   F+I ++ TFF +++R+RIVY++L R  +  E+G  + GI +L
Sbjct: 181 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 240

Query: 331 INNGSYIAAFPPHEGAY-KSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFG 389
           +N+ +Y +A+P H+G Y K S+P     P N R+ L++ WAR+  +YK QPLDLI+ Y+G
Sbjct: 241 LNSNTYSSAYPLHDGQYWKPSEP---PNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYG 297

Query: 390 EKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVFMCPLCD 446
           EKIG+YF +LG+YT ML  AA+VGL  F YGL +M ++  S EIC      ++ MCPLCD
Sbjct: 298 EKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCD 357

Query: 447 KNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEW 506
           + C   RLN +C+ +K ++LFDN  TVFFAIFM IW T+FLEFWK+R++ L Y WDL+++
Sbjct: 358 QVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDF 417

Query: 507 EEEEETL--RPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITA 564
           EEE++ L  RP+FEA   K   +N +T + EP+ P   ++    +S + +   +SLV+T+
Sbjct: 418 EEEQQQLQLRPEFEAMC-KHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTS 476

Query: 565 VFGVVVYRLVVMEQFASFKWN--FIKQYWQF-----ATSAAAVCINFIIIMLLNLAYEKI 617
           +  V+VYRL V   FASF  +   +KQ   F      TS    C+NFI+I++LN  YEKI
Sbjct: 477 MVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKI 536

Query: 618 AYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRW 677
           +  +T +E PRT  E+E+S  LKMFLFQFVN  SS FY+AFF G+FVG+PGKY  LF+ W
Sbjct: 537 SAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEW 596

Query: 678 RLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQW 737
           R EEC P GCLI+L  Q+ +IM  KQI+ N  E  YPL  NWW R K +    +    +W
Sbjct: 597 RSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTN-SEKLYSRW 655

Query: 738 ENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ 797
           E D +L+     GL  EYLE V QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K  TQ
Sbjct: 656 EQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQ 715

Query: 798 WRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPS 857
           +RR + ++A  IG+W  IL G+ +L+V TNAF++A TSD IPR VY Y Y    N  +P 
Sbjct: 716 YRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS--TNATQP- 772

Query: 858 ENCLKGYVNNSLSFFDLSELGMGKSG-------YCRYRDYRGPPWSSKPYEFTLQYWHIL 910
              + GYVNNSLS F +++     +         CRYRDYR PP     Y   +Q+WH+L
Sbjct: 773 ---MTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVL 829

Query: 911 AARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQ 967
           AA++ FIIV EH+VF +K  +A++IPDVPK + +RI+REK +  +++++ EL  L++
Sbjct: 830 AAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKE 886


>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
          Length = 912

 Score =  692 bits (1787), Expect = 0.0
 Identities = 388/896 (43%), Positives = 548/896 (61%), Gaps = 61/896 (6%)

Query: 106 LGKDKDYTDESEHATYDR--SRLINDFVIKDKSEFKTKLSKNDM---NYIASSGPLFKDG 160
           + K  DY+ +   +   R  S LIN+  +  K  F   L +  M   N  +     F+DG
Sbjct: 17  VNKHIDYSFQMSESLSSRETSFLINEETMPAK-RFNLFLRRRLMFQKNQQSKDSIFFRDG 75

Query: 161 KKRIDYILVY-----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPD--IMFIKIHIP 213
            ++ID++L Y     +   ++ ++R  FE NLR  GL LE E    S D    F+KIH P
Sbjct: 76  IRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAP 135

Query: 214 WDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDL 273
           W+ L  YAE L I+MP ++        +                    P+ L  S     
Sbjct: 136 WEVLVTYAEVLGIKMPIKESDIPRPKHTPIS-------------YVLGPVRLPLSV--KY 180

Query: 274 EESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKY--ENGISKVGIRKLI 331
              + +T  FSR R   F+I ++ TFF +++R+RIVY++L R  +  E+G  + GI +L+
Sbjct: 181 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240

Query: 332 NNGSYIAAFPPHEGAY-KSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGE 390
           N+ +Y +A+P H+G Y K S+P     P N R+ L++ WAR+  +YK QPLDLI+ Y+GE
Sbjct: 241 NSNTYSSAYPLHDGQYWKPSEP---PNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGE 297

Query: 391 KIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVFMCPLCDK 447
           KIG+YF +LG+YT ML  AA+VGL  F YGL +M ++  S EIC      ++ MCPLCD+
Sbjct: 298 KIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQ 357

Query: 448 NCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWE 507
            C   RLN +C+ +K ++LFDN  TVFFAIFM IW T+FLEFWK+R++ L Y WDL+++E
Sbjct: 358 VCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFE 417

Query: 508 EEEETL--RPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAV 565
           EE++ L  RP+FEA   K   +N +T + EP+ P   ++    +S + +   +SLV+T++
Sbjct: 418 EEQQQLQLRPEFEAMC-KHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSM 476

Query: 566 FGVVVYRLVVMEQFASFKWN--FIKQYWQF-----ATSAAAVCINFIIIMLLNLAYEKIA 618
             V+VYRL V   FASF  +   +KQ   F      TS    C+NFI+I++LN  YEKI+
Sbjct: 477 VAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKIS 536

Query: 619 YLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWR 678
             +T +E PRT  E+E+S  LKMFLFQFVN  SS FY+AFF G+FVG+PGKY  LF+ WR
Sbjct: 537 AWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWR 596

Query: 679 LEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQWE 738
            EEC P GCLI+L  Q+ +IM  KQI+ N  E  YPL  NWW R K +    +    +WE
Sbjct: 597 SEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTN-SEKLYSRWE 655

Query: 739 NDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQW 798
            D +L+     GL  EYLE V QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K  TQ+
Sbjct: 656 QDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQY 715

Query: 799 RRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE 858
           RR + ++A  IG+W  IL G+ +L+V TNAF++A TSD IPR VY Y Y    N  +P  
Sbjct: 716 RRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS--TNATQP-- 771

Query: 859 NCLKGYVNNSLSFFDLSELGMGKSG-------YCRYRDYRGPPWSSKPYEFTLQYWHILA 911
             + GYVNNSLS F +++     +         CRYRDYR PP     Y   +Q+WH+LA
Sbjct: 772 --MTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLA 829

Query: 912 ARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQ 967
           A++ FIIV EH+VF +K  +A++IPDVPK + +RI+REK +  +++++ EL  L++
Sbjct: 830 AKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKE 885


>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
          Length = 929

 Score =  654 bits (1686), Expect = 0.0
 Identities = 357/805 (44%), Positives = 504/805 (62%), Gaps = 60/805 (7%)

Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205
           F DG++RID++LVY     ++TN       Q  KR  +E NL   GL LE   ++    +
Sbjct: 62  FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 121

Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265
           +F+K+H PW+ LC YAE ++I++P +        RS + G +        NW  +   V 
Sbjct: 122 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 171

Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323
           +    P   E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+  N +S
Sbjct: 172 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 228

Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383
           K GI +L+N+G Y AAFP H+  ++     +     N R+LLY  WA     YK QPLDL
Sbjct: 229 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 286

Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440
           IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+  F YG    +N   S+E+C      ++ 
Sbjct: 287 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 346

Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500
           MCP CD+ C   +LN +C  +K   +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y 
Sbjct: 347 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 406

Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559
           WD +E ++EE+  RP++EA+   + ++N IT + E    ++  K  R+ +  S +FF I 
Sbjct: 407 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 464

Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611
           L+I +V G++VYRL V   F A    N      I++Y   Q ATS  A  I+FIIIM+LN
Sbjct: 465 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 524

Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671
             YEK+A ++TN E PRT++++ENS  +KMFLFQFVN  SS FYIAFF G+FVG+PG   
Sbjct: 525 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 584

Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730
               ++R EEC P GCL++L  Q+ +IM  K IWNN  E+  P I N   R H++     
Sbjct: 585 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 642

Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790
           +   P+WE D++LQPM   GL  EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D
Sbjct: 643 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 702

Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848
           A+K  TQ+RR +P +A DIG W  I++GI ILAV+TNA +IA TSD IPR VY + +   
Sbjct: 703 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 762

Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898
           P  +H   +   ++GY+NN+LS F +++            +G    CRYRD+R PP   +
Sbjct: 763 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 819

Query: 899 PYEFTLQYWHILAARLAFIIVFEHL 923
            Y+  + YWH++AA+LAFIIV E+L
Sbjct: 820 EYKHNIYYWHVIAAKLAFIIVMEYL 844


>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
          Length = 929

 Score =  654 bits (1686), Expect = 0.0
 Identities = 357/805 (44%), Positives = 504/805 (62%), Gaps = 60/805 (7%)

Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205
           F DG++RID++LVY     ++TN       Q  KR  +E NL   GL LE   ++    +
Sbjct: 62  FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 121

Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265
           +F+K+H PW+ LC YAE ++I++P +        RS + G +        NW  +   V 
Sbjct: 122 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 171

Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323
           +    P   E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+  N +S
Sbjct: 172 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 228

Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383
           K GI +L+N+G Y AAFP H+  ++     +     N R+LLY  WA     YK QPLDL
Sbjct: 229 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 286

Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440
           IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+  F YG    +N   S+E+C      ++ 
Sbjct: 287 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 346

Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500
           MCP CD+ C   +LN +C  +K   +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y 
Sbjct: 347 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 406

Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559
           WD +E ++EE+  RP++EA+   + ++N IT + E    ++  K  R+ +  S +FF I 
Sbjct: 407 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 464

Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611
           L+I +V G++VYRL V   F A    N      I++Y   Q ATS  A  I+FIIIM+LN
Sbjct: 465 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 524

Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671
             YEK+A ++TN E PRT++++ENS  +KMFLFQFVN  SS FYIAFF G+FVG+PG   
Sbjct: 525 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 584

Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730
               ++R EEC P GCL++L  Q+ +IM  K IWNN  E+  P I N   R H++     
Sbjct: 585 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 642

Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790
           +   P+WE D++LQPM   GL  EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D
Sbjct: 643 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 702

Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848
           A+K  TQ+RR +P +A DIG W  I++GI ILAV+TNA +IA TSD IPR VY + +   
Sbjct: 703 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 762

Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898
           P  +H   +   ++GY+NN+LS F +++            +G    CRYRD+R PP   +
Sbjct: 763 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 819

Query: 899 PYEFTLQYWHILAARLAFIIVFEHL 923
            Y+  + YWH++AA+LAFIIV E+L
Sbjct: 820 EYKHNIYYWHVIAAKLAFIIVMEYL 844


>gi|209862785 anoctamin 2 [Homo sapiens]
          Length = 998

 Score =  649 bits (1674), Expect = 0.0
 Identities = 356/826 (43%), Positives = 499/826 (60%), Gaps = 61/826 (7%)

Query: 178 DKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYT 237
           ++R  FE NL   GL LEK+    S   +F++IH PW  L + AE L I++P  KK Y  
Sbjct: 153 EQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVP-TKKMYEI 211

Query: 238 DGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKD 297
                   +     +++ + +   P V + S      +    + PFSR +++ + I  KD
Sbjct: 212 KAGGSIAKKFSAALQKLSSHL--QPRVPEHSN----NKMKNLSYPFSREKMYLYNIQEKD 265

Query: 298 TFFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHG 357
           TFF NATRSRIV+ +L+RT      + +GI  LI N  Y AA+P H+G Y S +      
Sbjct: 266 TFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPED----- 320

Query: 358 PQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVF 417
             N+R LLY+ WAR+G++YK QP+DLIR YFGEKIGLYFAWLG YT  LIP++++G+ VF
Sbjct: 321 DMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVF 380

Query: 418 FYGLFTMNNSQVSQEICKATEVF-MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFA 476
            YG  T+     S+E+C     F MCPLCDK+C    L+ +C  A+ ++LFDN  TVFF+
Sbjct: 381 LYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFS 440

Query: 477 IFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETL----RPQFEAKY----------- 521
           IFMA+WAT+FLE WKR +  L Y WDL   EEEEE      RP++E K            
Sbjct: 441 IFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQS 500

Query: 522 --YKMEIVNPITGKPEPHQPSS--DKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVME 577
              K+E      G  +     +  D+    L++ + I FMI+L  + VFGV+VYR+    
Sbjct: 501 AVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAA 560

Query: 578 QFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSF 637
             +  K    +   +   +A AV IN ++I++L+  Y  +A  LT +E P+TE  +E   
Sbjct: 561 ALSLNKAT--RSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERL 618

Query: 638 ALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGV 697
            LK FL +FVN  S IFY+AFF GRFVG PG Y  +FD +R+EEC P GCL++LC+Q+ +
Sbjct: 619 ILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSI 678

Query: 698 IMFLKQ-IWNNFMELGYPLIQNWWSRHKIKR------GIHDASIPQWENDWNLQPMNLHG 750
           IM  KQ I NN  E+G P ++  + + K +         H     QW+ D++L+P    G
Sbjct: 679 IMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYT--G 736

Query: 751 LMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIG 810
           L  EY+EM++QFGF T+FVA+FPLAP+ ALLNN+IE+RLDA KFVT+ RRP   R  DIG
Sbjct: 737 LTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIG 796

Query: 811 IWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLS 870
           IW  IL GIG  +VI+NAFVIAITSD+IPR VY+Y Y             L G+VN++LS
Sbjct: 797 IWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS--------HNGTLHGFVNHTLS 848

Query: 871 FFDLSELGMG----------KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVF 920
           FF++S+L  G          +  +CR++DYR PPW+  PYEF+ QYW IL+ARLAF+I+F
Sbjct: 849 FFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIF 908

Query: 921 EHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQ 966
           ++LV  +   + ++IPD+P  + D+I++EK L+ +   + E E L+
Sbjct: 909 QNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954


>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
           sapiens]
          Length = 986

 Score =  639 bits (1647), Expect = 0.0
 Identities = 358/858 (41%), Positives = 511/858 (59%), Gaps = 80/858 (9%)

Query: 179 KRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTD 238
           +R  +E NL   GL LE++       + F+KIH PW+ LC+ AE L ++MP  KK Y+ +
Sbjct: 127 RREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMP-TKKMYHIN 185

Query: 239 GRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDT 298
                + ++ +  ++I + +   P V +    P   +   Y  PFSR + H F +++KD+
Sbjct: 186 ETRGLLKKINSVLQKITDPI--QPKVAEHR--PQTMKRLSY--PFSREKQHLFDLSDKDS 239

Query: 299 FFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGP 358
           FF + TRS IVY +L+RT        +GI  L+ NG Y AA+P H+G Y           
Sbjct: 240 FFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENV-----E 294

Query: 359 QNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFF 418
            N+R LLYE WAR+G++YK+QP+DL+R YFGEKIGLYFAWLG YT MLIPA+IVG+ VF 
Sbjct: 295 FNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFL 354

Query: 419 YGLFTMNNSQVSQEIC-KATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAI 477
           YG  TM+ +  S E+C +   + MCPLCDK CS  +++ +C  A+ ++LFDN  TVFF++
Sbjct: 355 YGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSV 414

Query: 478 FMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETL----RPQFEA----KYYKMEIVNP 529
           FMA+WA  F+E WKR++  L Y WDL  +EEEEE +    R ++EA    K  K E  N 
Sbjct: 415 FMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNK 474

Query: 530 ITGKPEPHQPSS------------------------DKVTRLLVSVSGIFFMISLVITAV 565
              +  P + ++                        D+    L ++  I FMI++    V
Sbjct: 475 EKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIV 534

Query: 566 FGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLE 625
            GV++YR+ +    A      ++   +   +A AV IN ++I+LL+  Y  IA  LT +E
Sbjct: 535 LGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIE 594

Query: 626 YPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPS 685
            P+TE  +E     K FL +FVN  + IFY+AFF GRFVG PG Y  +F  +R+EEC P 
Sbjct: 595 VPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPG 654

Query: 686 GCLIDLCLQMGVIMFLKQ-IWNNFMELGYPLIQNWWSRHKIKRGI---HDASIPQ---WE 738
           GCL++LC+Q+ +IM  KQ I NN  E+G P ++      K+K+     H+  + +   +E
Sbjct: 655 GCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYE 714

Query: 739 NDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQW 798
            D+NL+P    GL  EY+EM++QFGF T+FVA+FPLAPL ALLNNIIEIRLDA KFVT+ 
Sbjct: 715 VDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTEL 772

Query: 799 RRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE 858
           RRP+  RA DIGIW  IL GIG LAVI NAFVI+ TSD+IPR VY Y Y           
Sbjct: 773 RRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYS--------KN 824

Query: 859 NCLKGYVNNSLSFFDLSELGMGKS-------GY----CRYRDYRGPPWSSKPYEFTLQYW 907
             + G+VN++LS F++S+   G +       GY    CRY+DYR PPWS   Y+ +  +W
Sbjct: 825 GTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFW 884

Query: 908 HILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEH--- 964
            +LAARLAF+IVF++LV  +  F+ ++IPD+PK +  +I +EK L+ E+    E +    
Sbjct: 885 AVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQL 944

Query: 965 ----LQQQRRKSGQPVHH 978
               ++++R+K   P +H
Sbjct: 945 LETWMEKERQKDEPPCNH 962


>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
           sapiens]
          Length = 933

 Score =  562 bits (1449), Expect = e-160
 Identities = 318/806 (39%), Positives = 477/806 (59%), Gaps = 54/806 (6%)

Query: 172 KTNIQYDKRNTFEKNLRAEGLMLEKEPAI-ASPDIMFIKIHIPWDTLCKYAERLNIRMPF 230
           +T++    R TF  NLRA GL ++++     +  + +  +   W  LC YAE L +++P 
Sbjct: 133 RTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPL 192

Query: 231 RKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHH 290
           ++             +   +   +  W+    ++L+    PD+   + Y+  F   ++  
Sbjct: 193 QEL----------PNQASNWSAGLLAWLGIPNVLLE--VVPDVPP-EYYSCRFRVNKLPR 239

Query: 291 FI-INNKDTFFSNATRSRIVYHMLERTKYENGISKV-GIRKLINNGSYIAAFPPHEGAYK 348
           F+  +N+DTFF++  R +I++ +L +T Y +    + GI +L+  G   AAFP H+G +K
Sbjct: 240 FLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFK 299

Query: 349 SSQPIKTHGPQ----NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTG 404
           +       GPQ    N R +L++ WARWG W K+QPLD +R YFGEK+ LYFAWLG+YTG
Sbjct: 300 TPP----EGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTG 355

Query: 405 MLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLCDKNCSLQRLNDSCIYAKV 463
            L+PAA+VG  VF  G F + +   +QE+C + + F MCPLC  +C    L+ +C  A+ 
Sbjct: 356 WLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQA 414

Query: 464 TYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYK 523
             LFD+GGTVFF++FMA+WA + LE+WKR+ + L Y WD  ++E+ EE  RPQF A    
Sbjct: 415 GRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASA-P 473

Query: 524 MEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFK 583
           M   NPITG+ EP+ P   +  R+L     I  M+++V+  +  +++YR  +M    S  
Sbjct: 474 MTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYR-AIMAIVVSRS 532

Query: 584 WNFIKQYWQFA-TSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMF 642
            N +   W     S     +N + I++L+  Y  +A++LT  E  RT++++E++F LK+F
Sbjct: 533 GNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVF 592

Query: 643 LFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLK 702
           +FQFVN  SS  YIAFF GRFVG+PG Y+ LF   R EEC   GCLI+L  ++ VIM  K
Sbjct: 593 IFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RNEECAAGGCLIELAQELLVIMVGK 651

Query: 703 QIWNNFMELGYPLIQNWWSRHKIKR------GIHDASIPQWENDWNLQPMNLHGLMDEYL 756
           Q+ NN  E+  P ++ WW + +++           AS   WE+D+ L P    GL DEYL
Sbjct: 652 QVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCE--GLFDEYL 709

Query: 757 EMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGIL 816
           EMVLQFGF TIFVAA PLAPL ALLNN +EIRLDA KFV ++RRP+  RA DIGIW  IL
Sbjct: 710 EMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHIL 769

Query: 817 EGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSE 876
            G+  LAVI+NAF++A +SD++PR  Y +             + L+G++N +L+    S 
Sbjct: 770 AGLTHLAVISNAFLLAFSSDFLPRAYYRW----------TRAHDLRGFLNFTLARAP-SS 818

Query: 877 LGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIP 936
                +  CRYR +R          ++  YW++LA RLAF+IVFEH+VF +   +  L+P
Sbjct: 819 FAAAHNRTCRYRAFR-----DDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873

Query: 937 DVPKGLHDRIRREKYLVQEMMYEAEL 962
           D+P+ +  +++RE YL ++ + E E+
Sbjct: 874 DIPESVEIKVKREYYLAKQALAENEV 899


>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
          Length = 782

 Score =  525 bits (1353), Expect = e-149
 Identities = 284/666 (42%), Positives = 396/666 (59%), Gaps = 55/666 (8%)

Query: 301 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN 360
           + + R RIV  ++   K   G +      L+ +G + A FP H+G  +            
Sbjct: 115 TTSLRIRIVNFVVMNNKTSAGET---FEDLMKDGVFEARFPLHKGEGR------------ 159

Query: 361 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG 420
               L + WARW   ++ QP+D IR YFGEK+ LYF WLGWYT ML+PAA+ GL VF  G
Sbjct: 160 ----LKKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSG 215

Query: 421 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA 480
                 SQ+S+EIC+A ++ MCPL D +   QRL+++C +AK+T+LFDN GTV FAIFMA
Sbjct: 216 FSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMA 275

Query: 481 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS 540
           +WATVFLE WKR+R+ +   WDL  W+EE+E +          ++++N    K  P+Q S
Sbjct: 276 LWATVFLEIWKRQRARVVLHWDLYVWDEEQEEM---------ALQLINCPDYKLRPYQHS 326

Query: 541 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV 600
             + T +LV       MI L+I     +VVYR++    F+S    F+++    A      
Sbjct: 327 YLRSTVILVLT---LLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGA 383

Query: 601 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL 660
            ++++ I+++      +A  L + E PRT SE E+ F ++ F  QF    SS+ YIAF L
Sbjct: 384 LVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFIL 443

Query: 661 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW 720
           GR  GHPGK  +L   W+LEECH SGC++DL +QM +IM LKQ  +N +E   P     W
Sbjct: 444 GRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVP-----W 498

Query: 721 SRHKIK--RGIHDASIPQ------WENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAF 772
             HK +  R      +P+      W  ++ L P+N   L DE++EM++Q+GFTTIFVAAF
Sbjct: 499 VTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAF 558

Query: 773 PLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIA 832
           PLAPLLAL +N++EIRLDA K V   RR +P +A DIG WL +LE IG+LAVI N  VIA
Sbjct: 559 PLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIA 618

Query: 833 ITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSEL-------GMGKSGYC 885
            TS++IPR VY+Y+Y PC      + +CLKGYVN+SLS F   +        G      C
Sbjct: 619 FTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLC 678

Query: 886 RYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDR 945
           RYRDYR PP     Y F+ Q+W +LA RLAF+I+FEH+   IK   A+ +PD+P+ + ++
Sbjct: 679 RYRDYRNPP----DYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNK 734

Query: 946 IRREKY 951
           +   KY
Sbjct: 735 VLEVKY 740


>gi|94536803 transmembrane protein 16K [Homo sapiens]
          Length = 660

 Score =  178 bits (452), Expect = 2e-44
 Identities = 166/567 (29%), Positives = 247/567 (43%), Gaps = 128/567 (22%)

Query: 294 NNKDTFFSNATRSRIVYHMLE--RTKYENGI----------SKVGIRKLINNGSYIAAFP 341
           +N D F + A    I+ H LE  R K E  I           K  +R+L+ +G  I  FP
Sbjct: 113 DNNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFP 172

Query: 342 PHEGAYKSSQPIKTHGPQNNRHLLYERW-ARWGMWYKHQPLDLIRLYFGEKIGLYFAWLG 400
            H+     S+ +K          L + W  R+ +  K+QP+D IR YFGE I LYF +L 
Sbjct: 173 LHD-----SEALKK---------LEDTWYTRFAL--KYQPIDSIRGYFGETIALYFGFLE 216

Query: 401 WYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIY 460
           ++T  LIP A++GL    Y LF   +                                 Y
Sbjct: 217 YFTFALIPMAVIGLP---YYLFVWED---------------------------------Y 240

Query: 461 AKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAK 520
            K          V FA F  IW+TV LE WKR  + +TY W  +  + + E  RP F   
Sbjct: 241 DKY---------VIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGV 291

Query: 521 YYKMEIVNPITGKPEPHQPSSDKVTRL-LVSVSGI---FFMISLVITAVFGVVVYRLVVM 576
                 +N ITGK EP  PS  +  R+ LVS+  +    +    V+   F + V+ L + 
Sbjct: 292 LG----INSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLH 347

Query: 577 EQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENS 636
           E   S +W  +  Y           I  I+I ++N  Y   A  LT+ E  R ES ++N 
Sbjct: 348 ENSGS-EWTSVLLY-------VPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNH 399

Query: 637 FALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMG 696
             LK+ +F F+N  +S+FYIAF L        K  KL                 L   + 
Sbjct: 400 LILKVLVFNFLNCFASLFYIAFVL--------KDMKL-----------------LRQSLA 434

Query: 697 VIMFLKQIWNNFMELGYPLIQNWWSRHK----IKRGIH----DASIPQWENDWNLQPMNL 748
            ++   QI N  ME   P    +W + K    +KR +     D     +E     + M  
Sbjct: 435 TLLITSQILNQIMESFLP----YWLQRKHGVRVKRKVQALKADIDATLYEQVILEKEMGT 490

Query: 749 H-GLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARAT 807
           + G  D+YLE+ LQFG+ ++F   +PLA   A+LNN  E+  DA K    ++RP    + 
Sbjct: 491 YLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSA 550

Query: 808 DIGIWLGILEGIGILAVITNAFVIAIT 834
           +IG+W    E + +++V+TN  +I ++
Sbjct: 551 NIGVWQLAFETMSVISVVTNCALIGMS 577



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 14/65 (21%), Positives = 37/65 (56%), Gaps = 4/65 (6%)

Query: 914 LAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAEL----EHLQQQR 969
           +  ++  EH +  +K  +A+ IPD P+ +  ++ R ++   E + + ++    E+L+++ 
Sbjct: 592 ILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEP 651

Query: 970 RKSGQ 974
            +SG+
Sbjct: 652 MESGK 656


>gi|55741655 anoctamin 8 [Homo sapiens]
          Length = 1232

 Score =  107 bits (268), Expect = 4e-23
 Identities = 103/384 (26%), Positives = 164/384 (42%), Gaps = 85/384 (22%)

Query: 291 FIINNKDT---FFSNATRSRIVYHMLERTKYENGISKVGIR---------KLINNGSYIA 338
           FI  N ++   FF++  R  I+   L+  + + G +   +R         +L   G    
Sbjct: 148 FIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQ 207

Query: 339 AFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAW 398
            FP HE              Q   + L + W +     ++QPLD I  YFG KI +YFAW
Sbjct: 208 VFPVHE--------------QRILNRLMKSWVQ--AVCENQPLDDICDYFGVKIAMYFAW 251

Query: 399 LGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSC 458
           LG+YT  ++  A+ G  ++ +        Q S+++                       SC
Sbjct: 252 LGFYTSAMVYPAVFGSVLYTF----TEADQTSRDV-----------------------SC 284

Query: 459 IYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWE-EEEETLRPQF 517
                         V FA+F  IW+T+FLE WKRR + L Y W  ++   E  E  RPQF
Sbjct: 285 --------------VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQF 330

Query: 518 EAKYYKMEIVNPITGKPEPHQPSSDKVT-RLLVSVSGIFFMISLVITAVFGVVVYRLVVM 576
                 +  ++PIT   E + P   ++  +LLVS+      +  V   + G    + +V+
Sbjct: 331 RG----VRRISPITRAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQELVL 386

Query: 577 EQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENS 636
                     +K   + A     V +  ++ +     Y+K+A  L ++E  R ES +E  
Sbjct: 387 S---------VKGLPRLARFLPKVMLALLVSVSAE-GYKKLAIWLNDMENYRLESAYEKH 436

Query: 637 FALKMFLFQFVNLNSSIFYIAFFL 660
             +K+ LFQFVN   S+FYI F+L
Sbjct: 437 LIIKVVLFQFVNSYLSLFYIGFYL 460



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 37/78 (47%), Positives = 54/78 (69%)

Query: 754 EYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWL 813
           +Y EM +QFG+  +F +AFPLA L AL+NN+IEIR DA+K  T  +RP   R   IG W 
Sbjct: 747 DYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQ 806

Query: 814 GILEGIGILAVITNAFVI 831
            ++E +G+LA++ N ++I
Sbjct: 807 KVMEAMGVLAIVVNCYLI 824



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 907 WHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMM--YEAELEH 964
           W    A +  ++V EH    +K  I   IPD+P  + + + + +Y  +E    +E + +H
Sbjct: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895

Query: 965 --LQQQRRK 971
              QQQRR+
Sbjct: 896 RYQQQQRRR 904


>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 719

 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 122/522 (23%), Positives = 187/522 (35%), Gaps = 158/522 (30%)

Query: 462 KVTYLFDNGGTVFFAIFMAIW-----------ATVFLEFW-------------------- 490
           K++ LFD+ GTVFF+IFM+ W           +      W                    
Sbjct: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313

Query: 491 -------KRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDK 543
                  +   S   + WD  +++++EE    QF A   +M   NP+TG  EP+      
Sbjct: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMT-QNPVTGLKEPYFQPHSC 372

Query: 544 VTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCIN 603
           ++ LL S + I  ++ +V+  +  V++Y  ++    A F                    N
Sbjct: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGII--SIAMFHTG-----------------N 413

Query: 604 FIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRF 663
            +++   N+                    W N     M   +  +L+ S+    FF    
Sbjct: 414 SVLMTQANVL-------------------WGNGGDASM---KMPSLSFSVCQFLFF---- 447

Query: 664 VGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQNW 719
                    L       +C P GC I +  Q+ +IM  KQ+ N+  E     G P     
Sbjct: 448 --------SLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP----- 494

Query: 720 WSRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLA 779
                   G     +P+                       LQFGF TIFV AF LAPL  
Sbjct: 495 --------GPDTPCLPE-----------------------LQFGFITIFVGAFLLAPLFT 523

Query: 780 LLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIP 839
           LLNN +EI LDA+KF+ +++RP+  R    G          ++   TNA           
Sbjct: 524 LLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA----------- 572

Query: 840 RFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKP 899
                 + G   N     +  + G      + F +      ++   RY+  R        
Sbjct: 573 ----RSRLGYWLN----GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DVG 619

Query: 900 YEFTLQYWHILA--ARLAFIIVFEHLVFGIKSFIAYLIPDVP 939
               L YW +LA    L FII FE++VF        L+PDVP
Sbjct: 620 VNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 14/23 (60%), Positives = 17/23 (73%)

Query: 360 NNRHLLYERWARWGMWYKHQPLD 382
           N+  LLY  WA WG W+K+QPLD
Sbjct: 227 NSCQLLYPYWACWGYWHKYQPLD 249


>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 723

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 129/583 (22%), Positives = 200/583 (34%), Gaps = 187/583 (32%)

Query: 401 WYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIY 460
           +Y   L+P  +VG  +F   L T+  + +                             ++
Sbjct: 226 FYMACLLPVTLVGTLLFISSLVTVGTNTL-----------------------------VW 256

Query: 461 AKVTYLFDNGGTVFFAIFMAIW-----------ATVFLEFW------------------- 490
             V  L D  GTVFF+IFM+ W           +      W                   
Sbjct: 257 VAVEGLGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHW 316

Query: 491 --------KRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSD 542
                   +   S   + WD  +++++EE    QF A   +M   NP+TG  EP+     
Sbjct: 317 DCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMT-QNPVTGLKEPYFQPHS 375

Query: 543 KVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCI 602
            ++ LL S + I  ++ +V+  +  V++Y  ++    A F                    
Sbjct: 376 CLSHLLTSSAAILTVLCVVMIFLVSVIIYHGII--SIAMFHTG----------------- 416

Query: 603 NFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGR 662
           N +++   N+                    W N     M   +  +L+ S+    FF   
Sbjct: 417 NSVLMTQANVL-------------------WGNGGDASM---KMPSLSFSVCQFLFF--- 451

Query: 663 FVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQN 718
                     L       +C P GC I +  Q+ +IM  KQ+ N+  E     G P    
Sbjct: 452 ---------SLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP---- 498

Query: 719 WWSRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLL 778
                    G     +P+                       LQFGF TIFV AF LAPL 
Sbjct: 499 ---------GPDTPCLPE-----------------------LQFGFITIFVGAFLLAPLF 526

Query: 779 ALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYI 838
            LLNN +EI LDA+KF+ +++RP+  R    G          ++   TNA          
Sbjct: 527 TLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA---------- 576

Query: 839 PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSK 898
                  + G   N     +  + G      + F +      ++   RY+  R       
Sbjct: 577 -----RSRLGYWLN----GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DV 622

Query: 899 PYEFTLQYWHILA--ARLAFIIVFEHLVFGIKSFIAYLIPDVP 939
                L YW +LA    L FII FE++VF        L+PDVP
Sbjct: 623 GVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 665


>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 494

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 74/266 (27%), Positives = 104/266 (39%), Gaps = 66/266 (24%)

Query: 680 EECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQNWWSRHKIKRGIHDASIP 735
           ++C P GC I +  Q+ +IM  KQ+ N+  E     G P             G     +P
Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP-------------GPDTPCLP 277

Query: 736 QWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFV 795
           +                       LQFGF TIFV AF LAPL  LLNN +EI LDA+KF+
Sbjct: 278 E-----------------------LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFL 314

Query: 796 TQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVE 855
            +++RP+  R    G          ++   TNA                 + G   N   
Sbjct: 315 CKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA---------------RSRLGYWLN--- 356

Query: 856 PSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILA--AR 913
             +  + G      + F +      ++   RY+  R            L YW +LA    
Sbjct: 357 -GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DVGVNLALFYWKLLAVHVH 410

Query: 914 LAFIIVFEHLVFGIKSFIAYLIPDVP 939
           L FII FE++VF        L+PDVP
Sbjct: 411 LGFIIAFENVVFFFLCPNDRLVPDVP 436



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 33/146 (22%)

Query: 462 KVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE----------- 510
           K++ LFD+ GTVFF+IFM+ W        +   + L + WD  +++++E           
Sbjct: 50  KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 109

Query: 511 ------ETLRP---------------QFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLV 549
                 + + P               +F A   +M   NP+TG  EP+      ++ LL 
Sbjct: 110 CSDFQDQEVMPSSALHHWDCSDFQDQEFAALALQM-TQNPVTGLKEPYFQPHSCLSHLLT 168

Query: 550 SVSGIFFMISLVITAVFGVVVYRLVV 575
           S + I  ++ +V+  +  V++Y  ++
Sbjct: 169 SSAAILTVLCVVMIFLVSVIIYHGII 194



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 14/23 (60%), Positives = 17/23 (73%)

Query: 360 NNRHLLYERWARWGMWYKHQPLD 382
           N+  LLY  WA WG W+K+QPLD
Sbjct: 23  NSCQLLYPYWACWGYWHKYQPLD 45


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 34.3 bits (77), Expect = 0.59
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 17  MNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSTESESQAPTSITLISTD 76
           M   +S +T +T    S R  P   +S   S+S S ST+LF S+  ++ +PT  T   TD
Sbjct: 91  MTSIESSVTSDTPGVSSTRMTP--TESRTTSESTSDSTTLFPSSTEDTSSPT--TPEGTD 146

Query: 77  KAEQVNTEENKNDSVLRCSFADLSDF 102
                 +EE+ + ++   S A L  F
Sbjct: 147 VPMSTPSEESISSTMAFVSTAPLPSF 172


>gi|114842410 zinc finger CCCH-type containing 11A [Homo sapiens]
          Length = 810

 Score = 33.9 bits (76), Expect = 0.77
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 12  KQQKGMNISKS--EITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSTESESQAPTS 69
           K +  +N+  S  ++     L P R+++   A   A  K LS S+S+ Q   ++  A   
Sbjct: 646 KAKPKVNVKPSVVKVVSSPKLAPKRKAVEMHAAVIAAVKPLS-SSSVLQEPPAKKAAVAV 704

Query: 70  ITLISTDKAEQVNTEENKNDSVL 92
           + L+S DK+  V   EN  DS++
Sbjct: 705 VPLVSEDKSVTVPEAENPRDSLV 727


>gi|5729862 stem-loop (histone) binding protein [Homo sapiens]
          Length = 270

 Score = 31.6 bits (70), Expect = 3.8
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 100 SDFCLALGKDKDYTD-ESEHATYDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFK 158
           SD+  A+ +D+  T    E A Y R  LINDF  + KS   +  SK  M+ + +     +
Sbjct: 73  SDWASAVEEDEMRTRVNKEMARYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFETDE 132

Query: 159 DGKKRIDYILVYRKTNIQYDKR-NTFEKNLRAEGL 192
               R    + Y K  I YD+      ++LR  G+
Sbjct: 133 SVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGI 167


>gi|148229509 G protein-coupled receptor 89A isoform 2 [Homo
           sapiens]
          Length = 335

 Score = 31.2 bits (69), Expect = 5.0
 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599
           SS+ +  LL  + G++F+ S+++  +   + YR ++ E     ++NF  +++      +A
Sbjct: 255 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 314

Query: 600 VCINFIIIMLLNLAYEK 616
           +      I+ L LA+++
Sbjct: 315 LS----SILFLYLAHKQ 327


>gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo
           sapiens]
          Length = 455

 Score = 31.2 bits (69), Expect = 5.0
 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599
           SS+ +  LL  + G++F+ S+++  +   + YR ++ E     ++NF  +++      +A
Sbjct: 375 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 434

Query: 600 VCINFIIIMLLNLAYEK 616
           +      I+ L LA+++
Sbjct: 435 LS----SILFLYLAHKQ 447


>gi|7706704 G protein-coupled receptor 89B [Homo sapiens]
          Length = 455

 Score = 31.2 bits (69), Expect = 5.0
 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599
           SS+ +  LL  + G++F+ S+++  +   + YR ++ E     ++NF  +++      +A
Sbjct: 375 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 434

Query: 600 VCINFIIIMLLNLAYEK 616
           +      I+ L LA+++
Sbjct: 435 LS----SILFLYLAHKQ 447


>gi|148234741 G protein-coupled receptor 89C [Homo sapiens]
          Length = 320

 Score = 31.2 bits (69), Expect = 5.0
 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599
           SS+ +  LL  + G++F+ S+++  +   + YR ++ E     ++NF  +++      +A
Sbjct: 240 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 299

Query: 600 VCINFIIIMLLNLAYEK 616
           +      I+ L LA+++
Sbjct: 300 LS----SILFLYLAHKQ 312


>gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]
          Length = 526

 Score = 30.8 bits (68), Expect = 6.5
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 38 PCLAQSYAYSKSLSQSTSLFQSTESESQAPT---SITLISTDKAEQVNTEENKNDSVL 92
          P L  S + S S SQ+ +   +  S   APT   S+T+++TD A+Q     +K + +L
Sbjct: 18 PLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDTAQQSTVPTSKANEIL 75


>gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]
          Length = 558

 Score = 30.8 bits (68), Expect = 6.5
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 38 PCLAQSYAYSKSLSQSTSLFQSTESESQAPT---SITLISTDKAEQVNTEENKNDSVL 92
          P L  S + S S SQ+ +   +  S   APT   S+T+++TD A+Q     +K + +L
Sbjct: 18 PLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDTAQQSTVPTSKANEIL 75


>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 30.4 bits (67), Expect = 8.5
 Identities = 12/23 (52%), Positives = 14/23 (60%)

Query: 873 DLSELGMGKSGYCRYRDYRGPPW 895
           D  +LG+GK  YCR  D R  PW
Sbjct: 93  DALQLGLGKHNYCRNPDNRRRPW 115


>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
           [Homo sapiens]
          Length = 431

 Score = 30.4 bits (67), Expect = 8.5
 Identities = 12/23 (52%), Positives = 14/23 (60%)

Query: 873 DLSELGMGKSGYCRYRDYRGPPW 895
           D  +LG+GK  YCR  D R  PW
Sbjct: 110 DALQLGLGKHNYCRNPDNRRRPW 132


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,460,986
Number of Sequences: 37866
Number of extensions: 1604783
Number of successful extensions: 5070
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4899
Number of HSP's gapped (non-prelim): 70
length of query: 981
length of database: 18,247,518
effective HSP length: 112
effective length of query: 869
effective length of database: 14,006,526
effective search space: 12171671094
effective search space used: 12171671094
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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