Search of human proteins with 11034843

Search of human proteins with 11034843

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11034843 ras homolog gene family, member U [Homo sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11034843 ras homolog gene family, member U [Homo sapiens]          538   e-153
gi|229577148 ras homolog gene family, member V [Homo sapiens]         272   2e-73
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           236   2e-62
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           236   2e-62
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            236   2e-62
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   218   3e-57
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   218   5e-57
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   214   6e-56
gi|50263042 ras-like protein TC10 [Homo sapiens]                      209   3e-54
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   207   1e-53
gi|16903164 ras homolog gene family, member J [Homo sapiens]          201   4e-52
gi|46249393 ras homolog gene family, member G [Homo sapiens]          195   4e-50
gi|111494251 ras homolog gene family, member C precursor [Homo s...   185   4e-47
gi|111494248 ras homolog gene family, member C precursor [Homo s...   185   4e-47
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   185   4e-47
gi|4757764 ras homolog gene family, member B [Homo sapiens]           181   4e-46
gi|10835049 ras homolog gene family, member A [Homo sapiens]          180   1e-45
gi|7656900 ras homolog D [Homo sapiens]                               157   9e-39
gi|38016957 ras homolog gene family, member F [Homo sapiens]          157   1e-38
gi|4885069 ras homolog gene family, member E [Homo sapiens]           147   1e-35
gi|4757770 ras homolog gene family, member H [Homo sapiens]           144   8e-35
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         141   5e-34
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    131   5e-31
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...   105   3e-23
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...   105   3e-23
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...   105   3e-23
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]        102   3e-22
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi...    94   1e-19
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ...    91   8e-19
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]            86   2e-17

>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  538 bits (1386), Expect = e-153
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV 60
           MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV
Sbjct: 1   MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV 60

Query: 61  GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN 120
           GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN
Sbjct: 61  GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN 120

Query: 121 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKE 180
           TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKE
Sbjct: 121 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKE 180

Query: 181 KPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTP 240
           KPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTP
Sbjct: 181 KPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTP 240

Query: 241 DKMKNLSKSWWKKYCCFV 258
           DKMKNLSKSWWKKYCCFV
Sbjct: 241 DKMKNLSKSWWKKYCCFV 258


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  272 bits (695), Expect = 2e-73
 Identities = 141/259 (54%), Positives = 181/259 (69%), Gaps = 24/259 (9%)

Query: 1   MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV 60
           MPP++   A P    AP  PPRR         P E             G+KCVLVGDGAV
Sbjct: 1   MPPRELSEAEPPPLRAPTPPPRRRSA------PPE------------LGIKCVLVGDGAV 42

Query: 61  GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN 120
           GK+SL+VSYT NGYP  Y PTA D FS  V VDG PVR++L DTAGQ++FD+LR LCY +
Sbjct: 43  GKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPD 102

Query: 121 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDK-CK 179
           TD+FL CFSVV PSSFQN++EKW+PEIR H P+AP++LVGTQ+DLR+DV VLI+LD+  +
Sbjct: 103 TDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGR 162

Query: 180 EKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRT 239
           E PVP+  A+  AE+I+A  Y+ECSALTQKNLKEVFD+AI++ I++    ++   +K   
Sbjct: 163 EGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKG-- 220

Query: 240 PDKMKNLSKSWWKKYCCFV 258
              ++ LS+  WKK+ CFV
Sbjct: 221 ---VRTLSRCRWKKFFCFV 236


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  236 bits (601), Expect = 2e-62
 Identities = 108/184 (58%), Positives = 141/184 (76%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDE 109
           +KCV+VGDGAVGKT L++SYTTN +P+EY+PT FDN++  V + G P  L L DTAGQ++
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 110 FDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDV 169
           +D+LRPL Y  TD+FL+CFSVVSPSSF+NV EKWVPEI  HCPK P +LVGTQ DLR+D 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDP 123

Query: 170 KVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQ 229
             + +L K K+KP+  E A+  A ++KA  Y+ECSALTQ+ LK VFD AI+A ++  +TQ
Sbjct: 124 STIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPPETQ 183

Query: 230 QQPK 233
            + K
Sbjct: 184 PKRK 187


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  236 bits (601), Expect = 2e-62
 Identities = 110/187 (58%), Positives = 142/187 (75%), Gaps = 4/187 (2%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDE 109
           +KCV+VGDGAVGKT L++SYTTN +P+EY+PT FDN++  V + G P  L L DTAGQ++
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 110 FDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDV 169
           +D+LRPL Y  TD+FL+CFSVVSPSSF+NV EKWVPEI  HCPK P +LVGTQ DLR+D 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDP 123

Query: 170 KVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQ 229
             + +L K K+KP+  E A+  A ++KA  Y+ECSALTQK LK VFD AI+A ++     
Sbjct: 124 STIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE----P 179

Query: 230 QQPKKSK 236
            +PKKS+
Sbjct: 180 PEPKKSR 186


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  236 bits (601), Expect = 2e-62
 Identities = 110/187 (58%), Positives = 142/187 (75%), Gaps = 4/187 (2%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDE 109
           +KCV+VGDGAVGKT L++SYTTN +P+EY+PT FDN++  V + G P  L L DTAGQ++
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 110 FDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDV 169
           +D+LRPL Y  TD+FL+CFSVVSPSSF+NV EKWVPEI  HCPK P +LVGTQ DLR+D 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDP 123

Query: 170 KVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQ 229
             + +L K K+KP+  E A+  A ++KA  Y+ECSALTQK LK VFD AI+A ++     
Sbjct: 124 STIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE----P 179

Query: 230 QQPKKSK 236
            +PKKS+
Sbjct: 180 PEPKKSR 186


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  218 bits (556), Expect = 3e-57
 Identities = 104/174 (59%), Positives = 131/174 (75%)

Query: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
           + +KCV+VGDGAVGKT L++SYTTN +P EYIPT FDN+SA V VDG+PV L L DTAGQ
Sbjct: 2   QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQ 61

Query: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167
           +++D+LRPL Y  TD+FL+CFS+VSP+SF+NV  KW PE+R HCP  PIILVGT+ DLR+
Sbjct: 62  EDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRD 121

Query: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVA 221
           D   + +L + K  P+        A+EI A  Y+ECSALTQ+ LK VFD AI A
Sbjct: 122 DKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRA 175


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  218 bits (554), Expect = 5e-57
 Identities = 104/186 (55%), Positives = 136/186 (73%)

Query: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
           + +KCV+VGDGAVGKT L++SYTTN +P EYIPT FDN+SA V VD +PV L L DTAGQ
Sbjct: 2   QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQ 61

Query: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167
           +++D+LRPL Y  TD+FL+CFS+VSP+S++NV  KW PE+R HCP  PIILVGT+ DLR+
Sbjct: 62  EDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRD 121

Query: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSD 227
           D   + +L + K  P+        A+EI +  Y+ECSALTQ+ LK VFD AI A +    
Sbjct: 122 DKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQP 181

Query: 228 TQQQPK 233
           T+QQ +
Sbjct: 182 TRQQKR 187


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  214 bits (545), Expect = 6e-56
 Identities = 102/174 (58%), Positives = 128/174 (73%)

Query: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
           + +KCV+VGDGAVGKT L++SYTTN +P EYIPT FDN+SA V VDG+PV L L DTAGQ
Sbjct: 2   QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQ 61

Query: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167
           +++D+LRPL Y  TD+FL+CFS+VSP+SF+NV  KW PE+R HCP  PI+LVGT+ DLR+
Sbjct: 62  EDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRD 121

Query: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVA 221
           D   +  L   K  P+        A EI +  Y+ECSALTQ+ LK VFD AI A
Sbjct: 122 DKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRA 175


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  209 bits (531), Expect = 3e-54
 Identities = 97/172 (56%), Positives = 130/172 (75%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDE 109
           +KCV+VGDGAVGKT L++SY  + +P EY+PT FD+++  V+V G+   L L DTAGQ++
Sbjct: 10  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69

Query: 110 FDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDV 169
           +D+LRPL Y  TD+FL+CFSVV+P+SFQNV E+WVPE++ + P  P +L+GTQ DLR+D 
Sbjct: 70  YDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDP 129

Query: 170 KVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVA 221
           K L  L+  KEKP+  E  +  A+EI A  Y+ECSALTQK LK VFD AI+A
Sbjct: 130 KTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIA 181


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  207 bits (526), Expect = 1e-53
 Identities = 104/193 (53%), Positives = 131/193 (67%), Gaps = 19/193 (9%)

Query: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
           + +KCV+VGDGAVGKT L++SYTTN +P EYIPT FDN+SA V VDG+PV L L DTAGQ
Sbjct: 2   QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQ 61

Query: 108 DEFDKLRPLCYTNT-------------------DIFLLCFSVVSPSSFQNVSEKWVPEIR 148
           +++D+LRPL Y  T                   D+FL+CFS+VSP+SF+NV  KW PE+R
Sbjct: 62  EDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVR 121

Query: 149 CHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQ 208
            HCP  PIILVGT+ DLR+D   + +L + K  P+        A+EI A  Y+ECSALTQ
Sbjct: 122 HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQ 181

Query: 209 KNLKEVFDAAIVA 221
           + LK VFD AI A
Sbjct: 182 RGLKTVFDEAIRA 194


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  201 bits (512), Expect = 4e-52
 Identities = 103/205 (50%), Positives = 136/205 (66%), Gaps = 7/205 (3%)

Query: 34  GEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVD 93
           G     G  G  E + +KCV+VGDGAVGKT L++SY  + +P EY+PT FD+++  V+V 
Sbjct: 6   GTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVG 65

Query: 94  GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153
           G+   L L DTAGQ+++++LRPL Y NTD+FL+CFSVV+P+S+ NV E+WVPE++   P 
Sbjct: 66  GKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPH 125

Query: 154 APIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKE 213
            P +L+GTQ DLR+D K L  L   KEKP+  E     A+ I A  Y+ECSALTQK LK 
Sbjct: 126 VPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKA 185

Query: 214 VFDAAIVAGIQYSDTQQQPKKSKSR 238
           VFD AI+       T   PKK K R
Sbjct: 186 VFDEAIL-------TIFHPKKKKKR 203


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  195 bits (495), Expect = 4e-50
 Identities = 91/174 (52%), Positives = 122/174 (70%)

Query: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
           + +KCV+VGDGAVGKT L++ YTTN +P EYIPT FDN+SA  +VDGR V L L DTAGQ
Sbjct: 2   QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61

Query: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167
           +E+D+LR L Y  T++F++CFS+ SP S++NV  KW PE+  HCP  PI+LVGT+ DLR 
Sbjct: 62  EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRA 121

Query: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVA 221
               L  L +  + P+  +  +  A++I A  Y+ECSAL Q  +KEVF  A+ A
Sbjct: 122 QPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRA 175


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  185 bits (469), Expect = 4e-47
 Identities = 85/174 (48%), Positives = 121/174 (69%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K V+VGDGA GKT L++ ++ + +P  Y+PT F+N+ A + VDG+ V L L DTAGQ+++
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
           D+LRPL Y +TD+ L+CFS+ SP S +N+ EKW PE++  CP  PIILVG + DLR+D  
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQ 224
              EL K K++PV  E  +  A  I A  Y+ECSA T++ ++EVF+ A  AG+Q
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  185 bits (469), Expect = 4e-47
 Identities = 85/174 (48%), Positives = 121/174 (69%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K V+VGDGA GKT L++ ++ + +P  Y+PT F+N+ A + VDG+ V L L DTAGQ+++
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
           D+LRPL Y +TD+ L+CFS+ SP S +N+ EKW PE++  CP  PIILVG + DLR+D  
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQ 224
              EL K K++PV  E  +  A  I A  Y+ECSA T++ ++EVF+ A  AG+Q
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  185 bits (469), Expect = 4e-47
 Identities = 85/174 (48%), Positives = 121/174 (69%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K V+VGDGA GKT L++ ++ + +P  Y+PT F+N+ A + VDG+ V L L DTAGQ+++
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
           D+LRPL Y +TD+ L+CFS+ SP S +N+ EKW PE++  CP  PIILVG + DLR+D  
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQ 224
              EL K K++PV  E  +  A  I A  Y+ECSA T++ ++EVF+ A  AG+Q
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  181 bits (460), Expect = 4e-46
 Identities = 84/174 (48%), Positives = 121/174 (69%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K V+VGDGA GKT L++ ++ + +P  Y+PT F+N+ A + VDG+ V L L DTAGQ+++
Sbjct: 7   KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
           D+LRPL Y +TD+ L+CFSV SP S +N+ EKWVPE++  CP  PIILV  + DLR D  
Sbjct: 67  DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEH 126

Query: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQ 224
           V  EL + K++PV  +  +  A  I+A  Y+ECSA T++ ++EVF+ A  A +Q
Sbjct: 127 VRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 180


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  180 bits (456), Expect = 1e-45
 Identities = 84/174 (48%), Positives = 118/174 (67%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K V+VGDGA GKT L++ ++ + +P  Y+PT F+N+ A + VDG+ V L L DTAGQ+++
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
           D+LRPL Y +TD+ L+CFS+ SP S +N+ EKW PE++  CP  PIILVG + DLR D  
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126

Query: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQ 224
              EL K K++PV  E  +  A  I A  Y+ECSA T+  ++EVF+ A  A +Q
Sbjct: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  157 bits (397), Expect = 9e-39
 Identities = 74/171 (43%), Positives = 106/171 (61%)

Query: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
           R VK VLVGDG  GKTSL++ +    +P  Y PT F+ +   + V G+PV L + DTAGQ
Sbjct: 16  RSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQ 75

Query: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167
           D++D+LRPL Y +  + LLCF V SP+SF N+  +W PE+   C K PII+VG ++DLR+
Sbjct: 76  DDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLRK 135

Query: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAA 218
           D  ++ +L +   +PV     +  A  + A +Y+ECSA    N+  VF  A
Sbjct: 136 DKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEA 186


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  157 bits (396), Expect = 1e-38
 Identities = 78/194 (40%), Positives = 125/194 (64%), Gaps = 1/194 (0%)

Query: 42  AGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQL 101
           A G   + +K V+VGDG  GKTSL++ Y+   +P  Y P+ F+ ++A V+V  + V L L
Sbjct: 12  APGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNL 71

Query: 102 CDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGT 161
            DTAGQ+++D+LRPL Y NT + L+C+ V++P+S+ NV  KW PE+   C   P++L+G 
Sbjct: 72  YDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGC 131

Query: 162 QSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVF-DAAIV 220
           ++DLR+D + L +L   + +P+         E+I+AA Y+ECSA  ++N+++VF +AA V
Sbjct: 132 KTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKV 191

Query: 221 AGIQYSDTQQQPKK 234
           A       Q+Q K+
Sbjct: 192 ALSALKKAQRQKKR 205


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  147 bits (370), Expect = 1e-35
 Identities = 75/198 (37%), Positives = 122/198 (61%), Gaps = 5/198 (2%)

Query: 48  RGVKC--VLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTA 105
           + VKC  V+VGD   GKT+L+  +  + +P  Y+PT F+N++A   +D + + L L DT+
Sbjct: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79

Query: 106 GQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDL 165
           G   +D +RPL Y ++D  L+CF +  P +  +V +KW  EI+  CP   ++LVG +SDL
Sbjct: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139

Query: 166 REDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKN-LKEVFDAAIVAGIQ 224
           R DV  L+EL   ++ PV  +     A++I AA+YIECSAL  +N ++++F  A +A + 
Sbjct: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV- 198

Query: 225 YSDTQQQPKKSKSRTPDK 242
            + T +  K++KS+   K
Sbjct: 199 -NKTNKNVKRNKSQRATK 215


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  144 bits (363), Expect = 8e-35
 Identities = 70/170 (41%), Positives = 106/170 (62%), Gaps = 7/170 (4%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDE 109
           +KCVLVGD AVGKTSL+V +T+  +P  Y PT ++N    V +DG  + L L DTAG D 
Sbjct: 5   IKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDA 64

Query: 110 FDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDV 169
           F  +RPL Y   D+ L+C+SV + +SF N+  KW+ EIR + P  P+++V TQ+D R   
Sbjct: 65  FRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQR--- 121

Query: 170 KVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAI 219
               E+   +   V     K  A++++A  Y+ECSAL+ + +++VF+ A+
Sbjct: 122 ----EMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAV 167


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  141 bits (356), Expect = 5e-34
 Identities = 67/181 (37%), Positives = 112/181 (61%), Gaps = 3/181 (1%)

Query: 46  EGRGVKC--VLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCD 103
           EG+  +C  V+VGD   GKT+L+  +  + YP  Y+PT F+N++A   +D R + L + D
Sbjct: 2   EGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWD 61

Query: 104 TAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQS 163
           T+G   +D +RPL Y ++D  L+CF +  P +  +V +KW  E +  CP A ++LVG + 
Sbjct: 62  TSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKL 121

Query: 164 DLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSA-LTQKNLKEVFDAAIVAG 222
           D+R D+  L EL K +  PV  E   + A+++ A SY+ECS+  +++++++VF  A VA 
Sbjct: 122 DMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVAS 181

Query: 223 I 223
           +
Sbjct: 182 L 182


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  131 bits (330), Expect = 5e-31
 Identities = 68/193 (35%), Positives = 112/193 (58%), Gaps = 3/193 (1%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K VLVGD   GKT+++     + YP  Y+PT F+N++A +  + + V L L DT+G   +
Sbjct: 15  KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
           D +RPLCY+++D  LLCF +  P +  +  +KW  EI  +CP   ++L+G ++DLR D+ 
Sbjct: 75  DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134

Query: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALT-QKNLKEVFDAAIVAGIQYSDTQ 229
            L+EL   K+ P+  E     A+++ A  Y+E SA T +K++  +F  A +  +  +   
Sbjct: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASM--LCLNKPS 192

Query: 230 QQPKKSKSRTPDK 242
             P+KS  R+  K
Sbjct: 193 PLPQKSPVRSLSK 205


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score =  105 bits (263), Expect = 3e-23
 Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 26/197 (13%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93
           +KCV+VGD AVGKT L+ +   N   T+Y      +PT  A D +     V        D
Sbjct: 15  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74

Query: 94  GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153
              V L+L DT G    D  R   Y  +D+ +LCFS+ +P+S  +V   W PEI+  CP+
Sbjct: 75  DVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 132

Query: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206
           AP+ILVG Q DLR  D++ +    +   +P+      P E  +  A+E+    Y E S +
Sbjct: 133 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVV 191

Query: 207 TQKNLKEVFDAAIVAGI 223
            Q  +K+VFD AI A +
Sbjct: 192 AQFGIKDVFDNAIRAAL 208


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score =  105 bits (263), Expect = 3e-23
 Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 26/197 (13%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93
           +KCV+VGD AVGKT L+ +   N   T+Y      +PT  A D +     V        D
Sbjct: 22  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 81

Query: 94  GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153
              V L+L DT G    D  R   Y  +D+ +LCFS+ +P+S  +V   W PEI+  CP+
Sbjct: 82  DVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 139

Query: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206
           AP+ILVG Q DLR  D++ +    +   +P+      P E  +  A+E+    Y E S +
Sbjct: 140 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVV 198

Query: 207 TQKNLKEVFDAAIVAGI 223
            Q  +K+VFD AI A +
Sbjct: 199 AQFGIKDVFDNAIRAAL 215


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score =  105 bits (263), Expect = 3e-23
 Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 26/197 (13%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93
           +KCV+VGD AVGKT L+ +   N   T+Y      +PT  A D +     V        D
Sbjct: 37  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 96

Query: 94  GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153
              V L+L DT G    D  R   Y  +D+ +LCFS+ +P+S  +V   W PEI+  CP+
Sbjct: 97  DVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154

Query: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206
           AP+ILVG Q DLR  D++ +    +   +P+      P E  +  A+E+    Y E S +
Sbjct: 155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVV 213

Query: 207 TQKNLKEVFDAAIVAGI 223
            Q  +K+VFD AI A +
Sbjct: 214 AQFGIKDVFDNAIRAAL 230


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score =  102 bits (255), Expect = 3e-22
 Identities = 70/197 (35%), Positives = 100/197 (50%), Gaps = 26/197 (13%)

Query: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93
           +KCV+VGD AVGKT L+ +   N   T+Y      +PT  A D +     V        D
Sbjct: 15  IKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74

Query: 94  GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153
              V L+L DT G    D  R   Y  +D+ +LCFS+ +P+S  +V   W PEI+  CP+
Sbjct: 75  EVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPR 132

Query: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206
            P+ILVG Q DLR  D++ +    +   +P+      P E  +  A+E+    Y E S  
Sbjct: 133 TPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVF 191

Query: 207 TQKNLKEVFDAAIVAGI 223
            Q  +K+VFD AI A +
Sbjct: 192 DQFGIKDVFDNAIRAAL 208


>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
           sapiens]
          Length = 218

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 64/210 (30%), Positives = 98/210 (46%), Gaps = 16/210 (7%)

Query: 26  GGRGGRGPGEP--GGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAF 83
           G   G G G P  GG G          K V+VG G VGK++L + +  + + ++Y PT  
Sbjct: 4   GAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIE 63

Query: 84  DNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKW 143
           D+++ + SVDG P RL + DTAGQ+EF  +R         FLL F++    SF  V + +
Sbjct: 64  DSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLF 123

Query: 144 VPEIRC-HCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIE 202
              +R       P++LVG ++DL              ++ VP   A         A Y E
Sbjct: 124 TQILRVKDRDDFPVVLVGNKADLE------------SQRQVPRSEASAFGASHHVA-YFE 170

Query: 203 CSALTQKNLKEVFDAAIVAGIQYSDTQQQP 232
            SA  + N+ E F+  + A  +Y + +  P
Sbjct: 171 ASAKLRLNVDEAFEQLVRAVRKYQEQELPP 200


>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
           sapiens]
          Length = 206

 Score = 91.3 bits (225), Expect = 8e-19
 Identities = 60/210 (28%), Positives = 108/210 (51%), Gaps = 21/210 (10%)

Query: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
           K ++VG G VGK++L + +  + +  +Y PT  D++   V +DG  V++ + DTAGQ+++
Sbjct: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75

Query: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSE--KWVPEIRCHCPKAPIILVGTQSDLRED 168
             +R   + + + FLL FS+    SF   +E  + +  ++    K P+++VG +SDL E 
Sbjct: 76  AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEE- 134

Query: 169 VKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDT 228
                       + VP E A+  AEE     Y+E SA T+ N+ +VF   ++  I+    
Sbjct: 135 -----------RRQVPVEEARSKAEE-WGVQYVETSAKTRANVDKVF-FDLMREIRTKKM 181

Query: 229 QQQPKKSKSRTPDKMKNLSKSWWKKYCCFV 258
            +   K+      K  + +K  +K+ CC +
Sbjct: 182 SENKDKN-----GKKSSKNKKSFKERCCLL 206


>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
          Length = 225

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 65/212 (30%), Positives = 102/212 (48%), Gaps = 28/212 (13%)

Query: 37  GGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNF-SAVVSVDGR 95
           GG G A        K VL+G+G VGKTSLV+ Y  N +  ++I T   +F +  +++ G+
Sbjct: 7   GGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGK 66

Query: 96  PVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIR------- 148
            V L + DTAGQ+ F  L P+ Y +++  +L + +    SFQ V + WV E+R       
Sbjct: 67  RVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKV-KNWVKELRKMLGNEI 125

Query: 149 CHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQ 208
           C C      +VG + DL             KE+ V  + A+  AE + A  Y   SA   
Sbjct: 126 CLC------IVGNKIDLE------------KERHVSIQEAESYAESVGAKHY-HTSAKQN 166

Query: 209 KNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTP 240
           K ++E+F       I+ +   ++ K + S  P
Sbjct: 167 KGIEELFLDLCKRMIETAQVDERAKGNGSSQP 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,351,173
Number of Sequences: 37866
Number of extensions: 676202
Number of successful extensions: 7487
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 279
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 5226
Number of HSP's gapped (non-prelim): 2041
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.