Guide to the Human Genome
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Search of human proteins with 156523268

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156523268 transcriptional adaptor 2 (ADA2 homolog,
yeast)-beta [Homo sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156523268 transcriptional adaptor 2 (ADA2 homolog, yeast)-bet...   857   0.0  
gi|68509270 transcriptional adaptor 2-like isoform a [Homo sapiens]   159   4e-39
gi|68509268 transcriptional adaptor 2-like isoform b [Homo sapiens]   121   1e-27
gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]                42   0.001
gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]                42   0.001
gi|56549694 enabled homolog isoform a [Homo sapiens]                   40   0.004
gi|39930375 enabled homolog isoform b [Homo sapiens]                   40   0.004
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            40   0.005
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    40   0.005
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         39   0.007
gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens]                39   0.009
gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens]                39   0.009
gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens]                39   0.009
gi|42717994 dystrobrevin alpha isoform 7 [Homo sapiens]                39   0.009
gi|189571587 dystrobrevin alpha isoform 9 [Homo sapiens]               39   0.009
gi|116686122 kinesin family member 4 [Homo sapiens]                    39   0.012
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    38   0.015
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            38   0.015
gi|148746195 trichohyalin [Homo sapiens]                               38   0.015
gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens]                38   0.020
gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]                38   0.020
gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]                38   0.020
gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens]                38   0.020
gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens]                38   0.020
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    37   0.026
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             37   0.026
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             37   0.026
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             37   0.026
gi|155030242 WD repeat domain 60 [Homo sapiens]                        37   0.034
gi|188536047 SWI/SNF-related matrix-associated actin-dependent r...    36   0.057

>gi|156523268 transcriptional adaptor 2 (ADA2 homolog, yeast)-beta
           [Homo sapiens]
          Length = 420

 Score =  857 bits (2215), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFT 60
           MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFT
Sbjct: 1   MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFT 60

Query: 61  LWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLG 120
           LWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLG
Sbjct: 61  LWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLG 120

Query: 121 KACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQD 180
           KACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQD
Sbjct: 121 KACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQD 180

Query: 181 AETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEK 240
           AETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEK
Sbjct: 181 AETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEK 240

Query: 241 EKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGIT 300
           EKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGIT
Sbjct: 241 EKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGIT 300

Query: 301 KMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCS 360
           KMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCS
Sbjct: 301 KMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCS 360

Query: 361 SLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS 420
           SLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS
Sbjct: 361 SLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS 420


>gi|68509270 transcriptional adaptor 2-like isoform a [Homo sapiens]
          Length = 443

 Score =  159 bits (402), Expect = 4e-39
 Identities = 121/445 (27%), Positives = 204/445 (45%), Gaps = 49/445 (11%)

Query: 6   KKYCVYCLAEVSPLRFRCTEC--QDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWG 63
           K  C  C + +     +C EC      LC +CF+ G E   H+  H Y+++     T   
Sbjct: 14  KPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIM-----TSDF 68

Query: 64  PEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKAC 123
           P  +  WT++EE  LL+A+   GFGNW+D+A  +  ++T +E  +HY+  +I+  L  + 
Sbjct: 69  PVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQM-CTKTKEECEKHYMKHFINNPLFAST 127

Query: 124 IPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAET 183
           + + +       T  +  P   +   P P  D S+  +   GYMP R D+  E+D  AE 
Sbjct: 128 LLN-LKQAEEAKTADTAIPFHSTDDPPRPTFD-SLLSRDMAGYMPARADFIEEFDNYAEW 185

Query: 184 LISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKA 243
            +  +    DD D+   LK A VD+Y  +LKERQRRK I RD+ L+          K + 
Sbjct: 186 DLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLI-------NLRKFQL 238

Query: 244 LKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKME 303
           ++R+  KE ++L   +R   + +   E D   E+   E  LR +I+ LQ YR  GIT   
Sbjct: 239 MERRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFC 298

Query: 304 ESAEYEAARHKREKRKENKNLAGS-----------------KRGKEDGKDSEFAAIEN-- 344
            +  Y+  +  RE+ +  + +                    +   + G         N  
Sbjct: 299 SARTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDSGLSPSIPMASNSG 358

Query: 345 -----------LPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIP-SKSR 392
                      LPG E L+++EK LC  + L P  Y+  K+ ++ +   K+ G+  +++R
Sbjct: 359 RRSAPPLNLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALLNE-CNKQGGLRLAQAR 417

Query: 393 LPSYLDKVLKKRILNFLTESGWISR 417
               +D    ++I +FL   G+I++
Sbjct: 418 ALIKIDVNKTRKIYDFLIREGYITK 442


>gi|68509268 transcriptional adaptor 2-like isoform b [Homo sapiens]
          Length = 305

 Score =  121 bits (304), Expect = 1e-27
 Identities = 83/274 (30%), Positives = 134/274 (48%), Gaps = 17/274 (6%)

Query: 6   KKYCVYCLAEVSPLRFRCTEC--QDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWG 63
           K  C  C + +     +C EC      LC +CF+ G E   H+  H Y+++     T   
Sbjct: 14  KPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIM-----TSDF 68

Query: 64  PEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKAC 123
           P  +  WT++EE  LL+A+   GFGNW+D+A  +  ++T +E  +HY+  +I+  L  + 
Sbjct: 69  PVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQM-CTKTKEECEKHYMKHFINNPLFAST 127

Query: 124 IPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAET 183
           + + +       T  +  P   +   P P  D S+  +   GYMP R D+  E+D  AE 
Sbjct: 128 LLN-LKQAEEAKTADTAIPFHSTDDPPRPTFD-SLLSRDMAGYMPARADFIEEFDNYAEW 185

Query: 184 LISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKA 243
            +  +    DD D+   LK A VD+Y  +LKERQRRK I RD+ L+          K + 
Sbjct: 186 DLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLI-------NLRKFQL 238

Query: 244 LKRKITKEEKELRLKLRPLYQFMSCKEFDDLFEN 277
           ++R+  KE ++L   +R   + +   E D   E+
Sbjct: 239 MERRYPKEVQDLYETMRRFARIVGPVEHDKFIES 272


>gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]
          Length = 743

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 37/165 (22%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAE 67
           C YC +E +   R+RC +C + +LC +CF  G   G H   H  +      +T W   A 
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMK-----EYTSWKSPA- 296

Query: 68  GGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDT 127
                   + L +A+ +         +    +SR P   M           L  A I DT
Sbjct: 297 --------KKLTNALSK---------SLSCASSREPLHPM---FPDQPEKPLNLAHIVDT 336

Query: 128 IPNR--------VTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQL 164
            P R        +  H+ PS G  SP +T   PP D  V + + L
Sbjct: 337 WPPRPVTSMNDTLFSHSVPSSG--SPFITRSSPPKDSEVEQNKLL 379


>gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]
          Length = 570

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 37/165 (22%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAE 67
           C YC +E +   R+RC +C + +LC +CF  G   G H   H  +      +T W   A 
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMK-----EYTSWKSPA- 296

Query: 68  GGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDT 127
                   + L +A+ +         +    +SR P   M           L  A I DT
Sbjct: 297 --------KKLTNALSK---------SLSCASSREPLHPM---FPDQPEKPLNLAHIVDT 336

Query: 128 IPNR--------VTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQL 164
            P R        +  H+ PS G  SP +T   PP D  V + + L
Sbjct: 337 WPPRPVTSMNDTLFSHSVPSSG--SPFITRSSPPKDSEVEQNKLL 379


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 43/195 (22%), Positives = 90/195 (46%), Gaps = 37/195 (18%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRL 257
           E+E++R       R+L+E+QR+K + R+       L +++ E+E+  + ++ +E    RL
Sbjct: 139 ELEIQR-------RQLQEQQRQKELERER------LERERMERERLERERLERE----RL 181

Query: 258 KLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREK 317
           +   L Q           E + +E+  R +   L+R  R  + + E     E    +R++
Sbjct: 182 ERERLEQ-----------EQLERERQERERQERLERQER--LERQERLERQERLDRERQE 228

Query: 318 RKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIII 377
           R+E + L   +R +++ +       E L   +L  +RE+ + S+   +PA   T    ++
Sbjct: 229 RQERERLERLERERQERERQ-----EQLEREQLEWERERRISSA--AAPASVETPLNSVL 281

Query: 378 KDHLQKRQGIPSKSR 392
            D      G+ + S+
Sbjct: 282 GDSSASEPGLQAASQ 296


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 43/195 (22%), Positives = 90/195 (46%), Gaps = 37/195 (18%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRL 257
           E+E++R       R+L+E+QR+K + R+       L +++ E+E+  + ++ +E    RL
Sbjct: 139 ELEIQR-------RQLQEQQRQKELERER------LERERMERERLERERLERE----RL 181

Query: 258 KLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREK 317
           +   L Q           E + +E+  R +   L+R  R  + + E     E    +R++
Sbjct: 182 ERERLEQ-----------EQLERERQERERQERLERQER--LERQERLERQERLDRERQE 228

Query: 318 RKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIII 377
           R+E + L   +R +++ +       E L   +L  +RE+ + S+   +PA   T    ++
Sbjct: 229 RQERERLERLERERQERERQ-----EQLEREQLEWERERRISSA--AAPASVETPLNSVL 281

Query: 378 KDHLQKRQGIPSKSR 392
            D      G+ + S+
Sbjct: 282 GDSSASEPGLQAASQ 296


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 24/139 (17%)

Query: 211 RKLKERQRRKNIARDYNLVPAFLGKDKKEKE-------KALKRKITKEEKELRLKLRPLY 263
           RK KE++ R   +++        GK+++ KE       K  +RK  + EKE   K R   
Sbjct: 115 RKKKEKKERGRTSKE--------GKERERKEERKREERKERERKKEEREKERERKERKKR 166

Query: 264 QFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENK- 322
           +     E ++  E   KE+  R K RE  R  R    + +E  E +  R K+E+RK+ + 
Sbjct: 167 ERKQVGEKEE--ERKEKERKERKK-RERNRKERKKERERKERRERKKERKKKEERKKERQ 223

Query: 323 -----NLAGSKRGKEDGKD 336
                N    +RGK + K+
Sbjct: 224 KDRQTNWREKERGKRERKE 242



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 25/109 (22%), Positives = 53/109 (48%)

Query: 214 KERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDD 273
           +ER+R +   R+         +++KE++K  ++++ ++E+E + K R   +       + 
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196

Query: 274 LFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENK 322
             E   KE+  R K R+ +  R+    K  ++   E  R KRE+++  K
Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 25/145 (17%)

Query: 212 KLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEF 271
           +++ER+R     ++        GK ++E E+  +R+  ++ K  R K R           
Sbjct: 37  EIREREREIETRKE--------GKKERESERKKERREREKRKREREKERKR--------- 79

Query: 272 DDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGK 331
               E   KEK    K  E +R +R    + +E  E E    KR+K+++ +    SK GK
Sbjct: 80  ----ERGKKEKKGERKKEERERKKRRREKENKEGEEKE----KRKKKEKKERGRTSKEGK 131

Query: 332 EDGKDSEFAAIENLPGFELLSDREK 356
           E  +  E    E         +REK
Sbjct: 132 ERERKEERKREERKERERKKEEREK 156



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 32/147 (21%), Positives = 65/147 (44%), Gaps = 9/147 (6%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKE--EKEL 255
           E E K+   +   RK +ER++ +   R          K+++E++K  + K  KE  EKE 
Sbjct: 56  ESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114

Query: 256 RLKLRPLYQFMSCKEF------DDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYE 309
           R K     +  + KE       ++      KE+  + + RE +R R+    +  +    +
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174

Query: 310 AARHKREKRKENKNLAGSKRGKEDGKD 336
               K ++RKE K    +++ ++  ++
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERE 201



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 257 LKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAA---RH 313
           +KL    Q +SC            +  +R + RE++  R+ G  + E   + E     + 
Sbjct: 11  VKLNTELQMVSCSHISKPCTQPGWQSEIREREREIET-RKEGKKERESERKKERREREKR 69

Query: 314 KREKRKENKNLAGSKRGKEDGKDSE 338
           KRE+ KE K   G K  K + K  E
Sbjct: 70  KREREKERKRERGKKEKKGERKKEE 94


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 18/138 (13%)

Query: 211 RKLKERQRRKNIARDYNLVPAFLGK-------------DKKEKEKALKRKITKEEKELRL 257
           RK +E   +  +  D  ++PA   K             DKK+K+K  K+K  KEEKE   
Sbjct: 274 RKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK-KKKGEKEEKEKEK 332

Query: 258 KLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREK 317
           K  P     + K   +    + KE+  R K  E +R +R    + +   E    + KRE+
Sbjct: 333 KKGP--SKATVKAMQEALAKL-KEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389

Query: 318 RKENKNLAGSKRGKEDGK 335
           +K+ K     +R K++GK
Sbjct: 390 KKQ-KEKERKERLKKEGK 406



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 30/170 (17%)

Query: 191 NYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEK-EKALKRKIT 249
           ++D+DD+  EL+   ++   + +K  +    +    N    F  KDKK+K +K  K+   
Sbjct: 52  DFDEDDILKELEELSLE--AQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFD 109

Query: 250 K------EEKELRLK--LRPLYQFMSCKEFDDLFENMHKEKMLRA--------------- 286
                  E+K+ + K   +P  +  S  + DD F  + K+   +A               
Sbjct: 110 DNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED 169

Query: 287 ---KIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKED 333
              KI+E  R   +G +  +ES E+  +R  ++K ++NK     + G ED
Sbjct: 170 NSKKIKERSRINSSGESG-DESDEFLQSRKGQKKNQKNKPGPNIESGNED 218



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 30/161 (18%), Positives = 70/161 (43%), Gaps = 14/161 (8%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRL 257
           E+E KR   +   ++ +ER+++K              K++KE+ K   + +TK ++E R 
Sbjct: 371 ELEAKRKEEERLEQEKRERKKQKE-------------KERKERLKKEGKLLTKSQREARA 417

Query: 258 KLRPLYQFMSCKEFD-DLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKRE 316
           +     + +  +  +    +++ K++ +    +  +  ++    ++ ES E  AA    E
Sbjct: 418 RAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVME 477

Query: 317 KRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKV 357
           +    K         E+ +D+E A +++        + EKV
Sbjct: 478 QGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKV 518


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 50/198 (25%), Positives = 90/198 (45%), Gaps = 26/198 (13%)

Query: 193 DDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKR--KITK 250
           +  ++E++ KR   + ++R  +E QR K +  +          +K EK +  +   ++ K
Sbjct: 686 EQQEIELQKKRQEEETFLRVQEELQRLKELNNN----------EKAEKFQIFQELDQLQK 735

Query: 251 EEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKM-EESAEYE 309
           E+ E   KL    + +  +E + +    H E+ LR K   +Q  RR  +  + EE  + E
Sbjct: 736 EKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLE 795

Query: 310 AARHKREKRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARY 369
             R    + KE +  AG   G EDG++ E A    L  FE    + + L   +NL   + 
Sbjct: 796 GIRESLLRVKEAR--AG---GDEDGEELEKA---QLRFFEF---KRRQLVKLVNLE--KD 842

Query: 370 VTVKTIIIKDHLQKRQGI 387
           +  +  I+K  +Q+ Q I
Sbjct: 843 LVQQKDILKKEVQEEQEI 860


>gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens]
          Length = 686

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC +E +   R+RC +C + +LC +CF  G   G H   H
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQH 284


>gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens]
          Length = 567

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC +E +   R+RC +C + +LC +CF  G   G H   H
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQH 284


>gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens]
          Length = 513

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC +E +   R+RC +C + +LC +CF  G   G H   H
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQH 284


>gi|42717994 dystrobrevin alpha isoform 7 [Homo sapiens]
          Length = 374

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC +E +   R+RC +C + +LC +CF  G   G H   H
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQH 284


>gi|189571587 dystrobrevin alpha isoform 9 [Homo sapiens]
          Length = 371

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC +E +   R+RC +C + +LC +CF  G   G H   H
Sbjct: 243 CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQH 284


>gi|116686122 kinesin family member 4 [Homo sapiens]
          Length = 1232

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 48/205 (23%), Positives = 91/205 (44%), Gaps = 27/205 (13%)

Query: 168 PLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYN 227
           P++  Y+   D   E  +  +++  + +++ +EL+ A  D    KL ER+R++   ++  
Sbjct: 552 PIQYQYQ---DNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKR--LQELE 606

Query: 228 LVPAFLGKDKKEKEKALK------RKITKEEKELRLKLRPLYQFM-SCKEFDDLFENMHK 280
              A L K   E+ K LK      R ++K  +E+R+      Q M   KE  + F    +
Sbjct: 607 GQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQ 666

Query: 281 EKMLRA-KIRELQRYRRNGITKMEES-----------AEYEAARHKREK---RKENKNLA 325
           +K     +++E  R R+  + K+E +            E  AA +KR K   +K+ +   
Sbjct: 667 KKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVAD 726

Query: 326 GSKRGKEDGKDSEFAAIENLPGFEL 350
             K  +  G +   A ++N  G E+
Sbjct: 727 KRKETQSRGMEGTAARVKNWLGNEI 751


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 42/185 (22%), Positives = 78/185 (42%), Gaps = 33/185 (17%)

Query: 160 EQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRR 219
           E++++  M L  +  +E+      ++       D D   + LK A   +Y  KLK+ + R
Sbjct: 729 EEERITTMQLEREKALEHKNRMSRMLE------DRDLFVMRLKAARQSVYEEKLKQFEER 782

Query: 220 KNIARDYNLVPAFLGKDKKEKEKALKRKIT----KEEKELRLKLRPLYQFMSCKEFDDLF 275
               R   L       +++++++  +R+IT    KEE+E R             E   L 
Sbjct: 783 LAEERHNRL-------EERKRQRKEERRITYYREKEEEEQRRA-----------EEQMLK 824

Query: 276 ENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAAR-----HKREKRKENKNLAGSKRG 330
           E   +E+  RAK  E  R  +  + K+EE    +  R      +  +R+E + L  S   
Sbjct: 825 EREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLS 884

Query: 331 KEDGK 335
           ++D +
Sbjct: 885 RKDSR 889



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 35/159 (22%), Positives = 77/159 (48%), Gaps = 20/159 (12%)

Query: 201 LKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLR 260
           +K AH+      L+E++ +  +A     V A+L   +KE ++ L R+ T EE++ RL+  
Sbjct: 537 IKPAHI------LQEKEEQHQLA-----VTAYLKNSRKEHQRILARRQTIEERKERLESL 585

Query: 261 PLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKE 320
            +      +E ++L     + ++ + +  E +R R+    + +E    E  + K++  +E
Sbjct: 586 NIQ-----REKEEL--EQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRE 638

Query: 321 N-KNLAGSKRGKEDGKDSEFAAIENL-PGFELLSDREKV 357
             + +  ++ G +  KD +   +E L P F +    E++
Sbjct: 639 RLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQL 677


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 5/139 (3%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRL 257
           E E KR       +K K+R+R K   R          K +KE+ +  +RK  KE+K+   
Sbjct: 51  EKERKRERGKKEKKKRKKRERGKERERKRKERE----KQRKERREKERRKRKKEKKKRER 106

Query: 258 KLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREK 317
           K R   +    KE  +  E  +K++  R + +  ++ RR    + +E  + E  R KR+K
Sbjct: 107 KQRGRRERKKKKERKER-ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165

Query: 318 RKENKNLAGSKRGKEDGKD 336
            +  K    +++ ++  ++
Sbjct: 166 EEREKKRERNRKERKKERE 184



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 25/128 (19%), Positives = 58/128 (45%)

Query: 211 RKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKE 270
           R+ KER++RK   +          + KK+KE+  + +  K+ +E + K R   +    ++
Sbjct: 89  RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148

Query: 271 FDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRG 330
            +       +++  R K    ++  RN   + +E    E    K+E++KE +     K+ 
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208

Query: 331 KEDGKDSE 338
           ++  + ++
Sbjct: 209 RKTDRQTD 216



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 26/104 (25%)

Query: 235 KDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRY 294
           K K+E+EK  KR+  K+EK+ R K                     KE+  + K RE QR 
Sbjct: 45  KRKREREKERKRERGKKEKKKRKK-----------------RERGKERERKRKEREKQR- 86

Query: 295 RRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSE 338
                   +E  E E  + K+EK+K  +   G +  K+  +  E
Sbjct: 87  --------KERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 41/200 (20%), Positives = 93/200 (46%), Gaps = 29/200 (14%)

Query: 160 EQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRR 219
           EQQ       R + ++  +Q+ E     L    +++  E +L+R   +  +R+ ++ +R 
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR---EQQLRREQQLRRE 392

Query: 220 KNIARDYNLVPAFLGKDKKEKEKALKRKIT-KEEKELRLKLRPLYQFMSCKEFDDLFENM 278
           + + R+  L           +E+ L+R+   + E++LR +     Q +  ++ ++  E  
Sbjct: 393 QQLRREQQL----------RREQQLRREQQLRREQQLRRE-----QQLRREQEEERHEQK 437

Query: 279 HKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSE 338
           H+++    +++  Q  RR+ + + EE+      RH++E+RK+       KR +E+ +   
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEET-----ERHEQERRKQQ-----LKRDQEEERRER 487

Query: 339 FAAIENLPGFELLSDREKVL 358
           +  +E     E    RE+ L
Sbjct: 488 WLKLEEEERREQQERREQQL 507



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 30/119 (25%), Positives = 60/119 (50%), Gaps = 15/119 (12%)

Query: 212 KLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEF 271
           KL+E +RR+   R    +       ++E+E+  ++++ ++E+E RL+ R   +    +E 
Sbjct: 490 KLEEEERREQQERREQQL-------RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542

Query: 272 DDLFENMHK---EKMLRAKIREL-----QRYRRNGITKMEESAEYEAARHKREKRKENK 322
           ++  E + K   EK L  + RE      Q  RR+ + K EE    +  + ++E+R E +
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 11/140 (7%)

Query: 198  EIELKRAHVDMYVRKLKERQRRKNIARDYNL-------VPAFLGKDKKEKEKALKRKITK 250
            E E  +   +  +R+ +E++RR+   R Y             LG++ +++ +  + K  +
Sbjct: 932  EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991

Query: 251  EEKELRLKLRPLYQFMSCKEFDDLFENMHKEK-MLRAKIRELQRYRRNGITKMEESAEYE 309
            EE+EL+ +   L +    K     +E  +++K  L+ +  +L R  R      E   +Y 
Sbjct: 992  EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY- 1050

Query: 310  AARHKREKRKENKNLAGSKR 329
              R + E ++E + L G +R
Sbjct: 1051 --REEEELQQEEEQLLGEER 1068



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 23/114 (20%), Positives = 55/114 (48%), Gaps = 5/114 (4%)

Query: 211  RKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLY----QFM 266
            R+ ++R+ R+   R       FL ++++ + +  +RK  KEE++LR + R       +  
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414

Query: 267  SCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKE 320
              +E +       +++  R + ++++R  R     +EE  +    RH++ + +E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERER-KFLEEEQQLRQERHRKFREEE 1467



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/127 (21%), Positives = 56/127 (44%), Gaps = 10/127 (7%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKR----KITKEEK 253
           E +L+R   +   ++LK ++  + + +          + ++ +E+ LKR    ++ +E +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563

Query: 254 ELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARH 313
           E RLK          +  D L +   + +  R K  + +R  +    +  E  E E  R 
Sbjct: 564 EQRLKRE------QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617

Query: 314 KREKRKE 320
           +R KR+E
Sbjct: 618 QRLKREE 624



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 13/133 (9%)

Query: 207  DMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFM 266
            +  +R+ +E++RR+   R Y          KK++ +  + ++ +EE+E R       Q+ 
Sbjct: 1001 EQLLREEREKRRRQEWERQYR---------KKDELQQEEEQLLREEREKRRLQERERQYR 1051

Query: 267  SCKEFDDLFENMHKEKMLRAKIRELQR-YRRNGITKMEESAEYEAARHKREKRKENKNLA 325
              +E     E +  E+    + +EL+R YR+    + EE    +  R + EKR+  +   
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE---QLLREEPEKRRRQERER 1108

Query: 326  GSKRGKEDGKDSE 338
              +  +E  ++ E
Sbjct: 1109 QCREEEELQQEEE 1121



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 37/176 (21%), Positives = 80/176 (45%), Gaps = 25/176 (14%)

Query: 169  LRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNL 228
            LR D + ++ ++ + L  G          E +L+R   D   R+ +++ RR+   R    
Sbjct: 1661 LRHDRDRKFREEEQLLQEG---------EEQQLRRQERDRKFREEEQQLRRQERER---- 1707

Query: 229  VPAFLGKDKKEKEKALKRKITKEEKELRL-----KLRPLYQFMSCKEFDDLFENMHKEKM 283
               FL ++++ + + L+RK  +EE++LR      +LR   ++    E + L     ++++
Sbjct: 1708 --KFLQEEQQLRRQELERKF-REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764

Query: 284  LR----AKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKEDGK 335
             R     K RE ++ R+    +   S E +    + E+ ++ +     +  + DGK
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 13/110 (11%)

Query: 214  KERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDD 273
            +E +RR+ + R Y          K+E+ +  + ++ +EE E R +     Q    +E   
Sbjct: 1068 RETRRRQELERQYR---------KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118

Query: 274  LFENMHKEKMLRAKIRELQR-YRRNGITKMEESAEYEAARHKREKRKENK 322
              E + +E+  + + +EL+R YR     + EE    +  R + EKR+  +
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEE---QLLREEPEKRRRQE 1165



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 16/150 (10%)

Query: 211  RKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKE 270
            R+ ++R+ R+   R       FL ++++   +  +RK  +EE++LR + R        + 
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER------GQQR 1549

Query: 271  FDDLFENMHKEKMLRAKIRE--LQRYRRNGITKMEES--AEYEAARHKREKRKENKNLAG 326
              D      +E+ LR +  E  L R  R+   ++EE      E  R   E  ++ +   G
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609

Query: 327  SKRGKEDGKDSEFAAIENLPGFELLSDREK 356
             ++ +++ +D +F   E     +LL +RE+
Sbjct: 1610 QQQLRQE-RDRKFREDE-----QLLQEREE 1633



 Score = 28.9 bits (63), Expect = 9.1
 Identities = 28/138 (20%), Positives = 65/138 (47%), Gaps = 11/138 (7%)

Query: 198 EIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKR---KITKEEKE 254
           E +L+R  +    RK +E ++++   R   +      K+ +++E  L++   K+ +EE +
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ 266

Query: 255 LRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHK 314
            + +L+   + +   E  +L     +E+  + ++R  Q+ RR    K EE    E    +
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR----KQEE----ERREQQ 318

Query: 315 REKRKENKNLAGSKRGKE 332
            E+R++ +     +  +E
Sbjct: 319 EERREQQERREQQEERRE 336



 Score = 28.9 bits (63), Expect = 9.1
 Identities = 24/127 (18%), Positives = 59/127 (46%), Gaps = 14/127 (11%)

Query: 207  DMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFM 266
            +  +R+ +E++R +   R Y          ++E+ +  + ++  EE+E R +     Q+ 
Sbjct: 1031 EQLLREEREKRRLQERERQYR---------EEEELQQEEEQLLGEERETRRRQELERQYR 1081

Query: 267  SCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAG 326
              +E         +E++LR +  + +R  R    + EE  + E  +  RE+R++ +    
Sbjct: 1082 KEEELQQ-----EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136

Query: 327  SKRGKED 333
             ++ +E+
Sbjct: 1137 ERQYREE 1143


>gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens]
          Length = 627

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC  E +   R+RC +C + +LC  CF  G   G H   H
Sbjct: 243 CSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQH 284


>gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]
          Length = 567

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC  E +   R+RC +C + +LC  CF  G   G H   H
Sbjct: 243 CSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQH 284


>gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]
          Length = 597

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC  E +   R+RC +C + +LC  CF  G   G H   H
Sbjct: 243 CSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQH 284


>gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens]
          Length = 560

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC  E +   R+RC +C + +LC  CF  G   G H   H
Sbjct: 243 CSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQH 284


>gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens]
          Length = 609

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 9   CVYCLAE-VSPLRFRCTECQDIELCPECFSAGAEIGHHRRYH 49
           C YC  E +   R+RC +C + +LC  CF  G   G H   H
Sbjct: 243 CSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQH 284


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 40/165 (24%), Positives = 68/165 (41%), Gaps = 40/165 (24%)

Query: 192 YDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKE 251
           ++D D +++LK    D  VRK KE+ + K   R+         K KK+K+K  K K+  +
Sbjct: 595 FEDVDPKVKLK----DGLVRKEKEKHKDKKKDRE---------KGKKDKDKREKEKVKDK 641

Query: 252 EKELRLKLRPLYQFMSCKEF-------------------------DDLFENMHKEKMLRA 286
            +E ++K       +  KE                          + LFE   KEK+   
Sbjct: 642 GREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEE--KEKVKEK 699

Query: 287 KIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGK 331
           + ++ ++ ++    K +E  E E  + KRE+ K  K     K  K
Sbjct: 700 EKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEK 744


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 12/98 (12%)

Query: 235 KDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRY 294
           K +   E AL  +  K+EKELR + +           ++  E + KE+    K ++ Q  
Sbjct: 462 KARIHAETALLMEKNKQEKELRERQQ-----------EEQKEKLRKEEQ-EQKAKKKQEA 509

Query: 295 RRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKE 332
             N IT+ ++ A+ E  + + E+ K+      +KRGKE
Sbjct: 510 EENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKE 547


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 12/98 (12%)

Query: 235 KDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRY 294
           K +   E AL  +  K+EKELR + +           ++  E + KE+    K ++ Q  
Sbjct: 462 KARIHAETALLMEKNKQEKELRERQQ-----------EEQKEKLRKEEQ-EQKAKKKQEA 509

Query: 295 RRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKE 332
             N IT+ ++ A+ E  + + E+ K+      +KRGKE
Sbjct: 510 EENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKE 547


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 12/98 (12%)

Query: 235 KDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRY 294
           K +   E AL  +  K+EKELR + +           ++  E + KE+    K ++ Q  
Sbjct: 462 KARIHAETALLMEKNKQEKELRERQQ-----------EEQKEKLRKEEQ-EQKAKKKQEA 509

Query: 295 RRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKE 332
             N IT+ ++ A+ E  + + E+ K+      +KRGKE
Sbjct: 510 EENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKE 547


>gi|155030242 WD repeat domain 60 [Homo sapiens]
          Length = 1066

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 10/139 (7%)

Query: 211 RKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKE----EKELRLKLRPLYQFM 266
           R+ +ER+ +   ++D N +  +L K++ E+     R+  ++    EK    + R  Y   
Sbjct: 185 RRYRERKLQYGDSKD-NPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKE 243

Query: 267 SCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAG 326
               F D  E  HKEK  +          ++ + + E+SA+ E  + + +  +     A 
Sbjct: 244 KSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGAS 303

Query: 327 SKRGKEDGKDSEFAAIENL 345
           SKR   DG  S+ A  ENL
Sbjct: 304 SKR---DGTSSQHA--ENL 317


>gi|188536047 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c1 [Homo sapiens]
          Length = 1105

 Score = 36.2 bits (82), Expect = 0.057
 Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 2/53 (3%)

Query: 63  GPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYI 115
           G  A   WT +E  LLL+A+E +   +W  ++ HVG SRT  E + H++ + I
Sbjct: 616 GASAGREWTEQETLLLLEALEMYK-DDWNKVSEHVG-SRTQDECILHFLRLPI 666


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,007,595
Number of Sequences: 37866
Number of extensions: 843791
Number of successful extensions: 5144
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 4586
Number of HSP's gapped (non-prelim): 683
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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