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Search of human proteins with 156231351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo
sapiens]
(1359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo sapi... 2719 0.0
gi|156231353 Niemann-Pick C1-like protein 1 isoform 2 [Homo sapi... 2649 0.0
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens] 894 0.0
gi|52145305 patched 2 [Homo sapiens] 110 9e-24
gi|134254450 patched isoform S [Homo sapiens] 110 1e-23
gi|134254435 patched isoform S [Homo sapiens] 110 1e-23
gi|134254468 patched isoform S [Homo sapiens] 110 1e-23
gi|134254452 patched isoform S [Homo sapiens] 110 1e-23
gi|134254432 patched isoform L' [Homo sapiens] 110 1e-23
gi|134254466 patched isoform M [Homo sapiens] 110 1e-23
gi|134254446 patched isoform L [Homo sapiens] 110 1e-23
gi|194018513 patched domain containing 3 [Homo sapiens] 99 2e-20
gi|148277106 hypothetical protein LOC442213 [Homo sapiens] 96 2e-19
gi|66932902 SREBF chaperone protein [Homo sapiens] 74 7e-13
gi|148271104 patched domain containing 1 [Homo sapiens] 70 1e-11
gi|149274653 patched domain containing 2 [Homo sapiens] 49 3e-05
gi|25121980 dispatched B [Homo sapiens] 46 3e-04
gi|25952134 dispatched A [Homo sapiens] 41 0.007
gi|94680985 cyclin J-like [Homo sapiens] 41 0.009
gi|58331120 hypothetical protein LOC29058 isoform 1 [Homo sapiens] 40 0.012
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s... 39 0.034
gi|187608508 centromere protein L isoform 1 [Homo sapiens] 37 0.099
gi|239744440 PREDICTED: hypothetical protein XP_002343124 [Homo ... 36 0.22
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 36 0.29
gi|28372523 intraflagellar transport protein IFT20 [Homo sapiens] 36 0.29
gi|34147532 myosin, light chain 10, regulatory [Homo sapiens] 35 0.37
gi|239755619 PREDICTED: hypothetical protein [Homo sapiens] 35 0.37
gi|239750132 PREDICTED: hypothetical protein XP_002347267 [Homo ... 35 0.37
gi|237858664 hypothetical protein LOC123207 isoform b [Homo sapi... 35 0.37
gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens] 35 0.64
>gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo sapiens]
Length = 1359
Score = 2719 bits (7048), Expect = 0.0
Identities = 1359/1359 (100%), Positives = 1359/1359 (100%)
Query: 1 MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSN 60
MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSN
Sbjct: 1 MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSN 60
Query: 61 TPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNF 120
TPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNF
Sbjct: 61 TPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNF 120
Query: 121 VNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAA 180
VNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAA
Sbjct: 121 VNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAA 180
Query: 181 ATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGV 240
ATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGV
Sbjct: 181 ATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGV 240
Query: 241 ARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTI 300
ARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTI
Sbjct: 241 ARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTI 300
Query: 301 LLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSV 360
LLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSV
Sbjct: 301 LLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSV 360
Query: 361 IPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSY 420
IPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSY
Sbjct: 361 IPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSY 420
Query: 421 RYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNT 480
RYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNT
Sbjct: 421 RYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNT 480
Query: 481 SLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALAL 540
SLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALAL
Sbjct: 481 SLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALAL 540
Query: 541 SCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEM 600
SCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEM
Sbjct: 541 SCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEM 600
Query: 601 RAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRV 660
RAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRV
Sbjct: 601 RAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRV 660
Query: 661 MVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLE 720
MVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLE
Sbjct: 661 MVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLE 720
Query: 721 YQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAV 780
YQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAV
Sbjct: 721 YQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAV 780
Query: 781 ILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFL 840
ILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFL
Sbjct: 781 ILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFL 840
Query: 841 LHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPV 900
LHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPV
Sbjct: 841 LHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPV 900
Query: 901 YFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDW 960
YFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDW
Sbjct: 901 YFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDW 960
Query: 961 LTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRP 1020
LTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRP
Sbjct: 961 LTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRP 1020
Query: 1021 NIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYH 1080
NIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYH
Sbjct: 1021 NIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYH 1080
Query: 1081 KPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGL 1140
KPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGL
Sbjct: 1081 KPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGL 1140
Query: 1141 FMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVS 1200
FMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVS
Sbjct: 1141 FMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVS 1200
Query: 1201 AVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQ 1260
AVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQ
Sbjct: 1201 AVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQ 1260
Query: 1261 LIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCP 1320
LIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCP
Sbjct: 1261 LIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCP 1320
Query: 1321 NHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF 1359
NHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF
Sbjct: 1321 NHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF 1359
>gi|156231353 Niemann-Pick C1-like protein 1 isoform 2 [Homo sapiens]
Length = 1332
Score = 2649 bits (6867), Expect = 0.0
Identities = 1331/1359 (97%), Positives = 1331/1359 (97%), Gaps = 27/1359 (1%)
Query: 1 MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSN 60
MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSN
Sbjct: 1 MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSN 60
Query: 61 TPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNF 120
TPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNF
Sbjct: 61 TPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNF 120
Query: 121 VNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAA 180
VNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAA
Sbjct: 121 VNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAA 180
Query: 181 ATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGV 240
ATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGV
Sbjct: 181 ATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGV 240
Query: 241 ARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTI 300
ARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTI
Sbjct: 241 ARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTI 300
Query: 301 LLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSV 360
LLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSV
Sbjct: 301 LLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSV 360
Query: 361 IPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSY 420
IPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSY
Sbjct: 361 IPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSY 420
Query: 421 RYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNT 480
RYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNT
Sbjct: 421 RYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNT 480
Query: 481 SLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALAL 540
SLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALAL
Sbjct: 481 SLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALAL 540
Query: 541 SCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEM 600
SCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEM
Sbjct: 541 SCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEM 600
Query: 601 RAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRV 660
RAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRV
Sbjct: 601 RAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRV 660
Query: 661 MVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLE 720
MVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLE
Sbjct: 661 MVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLE 720
Query: 721 YQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAV 780
YQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAV
Sbjct: 721 YQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAV 780
Query: 781 ILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFL 840
ILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFL
Sbjct: 781 ILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFL 840
Query: 841 LHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPV 900
LHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPV
Sbjct: 841 LHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPV 900
Query: 901 YFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDW 960
YFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDW
Sbjct: 901 YFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDW 960
Query: 961 LTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRP 1020
LTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRP
Sbjct: 961 LTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRP 1020
Query: 1021 NIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYH 1080
NIKCPKGGLAAYSTSVNLTSDGQVL SRFMAYH
Sbjct: 1021 NIKCPKGGLAAYSTSVNLTSDGQVL---------------------------ASRFMAYH 1053
Query: 1081 KPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGL 1140
KPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGL
Sbjct: 1054 KPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGL 1113
Query: 1141 FMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVS 1200
FMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVS
Sbjct: 1114 FMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVS 1173
Query: 1201 AVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQ 1260
AVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQ
Sbjct: 1174 AVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQ 1233
Query: 1261 LIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCP 1320
LIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCP
Sbjct: 1234 LIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCP 1293
Query: 1321 NHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF 1359
NHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF
Sbjct: 1294 NHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF 1332
>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
Length = 1278
Score = 894 bits (2310), Expect = 0.0
Identities = 516/1315 (39%), Positives = 756/1315 (57%), Gaps = 82/1315 (6%)
Query: 7 RGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKI 66
RG L LLL L ++ ++ C +Y ECG +C + P + +
Sbjct: 4 RGLALGLLLLLLCPAQVFSQS-----CVWYGECG-------IAYGDKRYNCEYSGPPKPL 51
Query: 67 TGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCH 126
D L+Q++CP + G N CC +QL +L+ +L + L+RCP+C N +NL C
Sbjct: 52 PKDGYDLVQELCPGFFFG-NVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCE 110
Query: 127 NTCSPNQSLFINVTR----VAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAAT 182
TCSP QS F+NVT V + V + + SFA Y++C V P++
Sbjct: 111 LTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSND 170
Query: 183 LAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGVAR 242
A+G +CG A CNA W+ + + NG AP IT + G++P+N
Sbjct: 171 KALGLLCGKDADA-CNATNWIEYMFNKDNGQAPFTITPVFSD---FPVHGMEPMNNATKG 226
Query: 243 CNESQGDDVATCSCQDCAASCPAIARPQ---------ALDSTFYLGQMPGSLVLIIILCS 293
C+ES + A CSCQDC+ C +P LD+ + + + L++ +
Sbjct: 227 CDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGA 286
Query: 294 VFAVVTILLVGF--RVAPARDK---SKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWV 348
FAV F P S K S D +S + L + F WG++
Sbjct: 287 FFAVWCYRKRYFVSEYTPIDSNIAFSVNASDKGEASCCDPVSAAFEGCLRRLFTRWGSFC 346
Query: 349 ASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTN 408
P ++ S++ + A ++GLVF +TT+PV+LWSAP+SQAR EK + DQHFGPFFRT
Sbjct: 347 VRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTE 406
Query: 409 QVILTAPNRSSYRYDSLLLGPK-NFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISL 467
Q+I+ AP + Y G F LD+ +L ++L+LQ + ++ + ++L
Sbjct: 407 QLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENIT--ASYDNETVTL 464
Query: 468 QDICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCAN 527
QDIC APL+P NT+ C I S+L YFQN+ ++L D+ HFLYC
Sbjct: 465 QDICLAPLSPYNTN---CTILSVLNYFQNSHSVLDHKKGDDFF---VYADYHTHFLYCVR 518
Query: 528 APLTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLA 587
AP + D + L C+ +G PVFP+L +GGY ++Y+ A AL++TF +NNY +L
Sbjct: 519 APASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQ 578
Query: 588 QAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYI 647
+A+ WE+ F+ ++ ++ ++F AERS+EDE+NR + D+ SY ++FLYI
Sbjct: 579 RAQAWEKEFINFVKNYKNPN---LTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYI 635
Query: 648 SLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVL 707
SLALG S R++VDSK +LG+ G+ +VL +V ++G FSY+G+ +L++++V+PFLVL
Sbjct: 636 SLALGHIKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVL 695
Query: 708 SVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMP 767
+VG DNIFI V YQR R GE + +GR LG VAPSM L S SE + FFLGAL+ MP
Sbjct: 696 AVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMP 755
Query: 768 AVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQG-EG 826
AV TF+L +GLAV +DFLLQ++ FV+LL LD KRQE +RLD+ CCV+ E Q E
Sbjct: 756 AVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASES 815
Query: 827 LLLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDY 886
L FF+ +Y+P LL R +V+ +F+ + S+ + + +GLDQ L++P DSY++DY
Sbjct: 816 CLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDY 875
Query: 887 FLFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYL 946
F +++Y G PVYFV G++++S G N +C GCNN S Q+I A + + +
Sbjct: 876 FKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRI 935
Query: 947 AIPASSWVDDFIDWLTP-SSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITM-GSVRPS 1004
SSW+DD+ DW+ P SSCCR+ D+FC ++V C++ C +T G RP
Sbjct: 936 GFAPSSWIDDYFDWVKPQSSCCRV---DNITDQFCNASVVDPACVR-CRPLTPEGKQRPQ 991
Query: 1005 VEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAH 1064
F ++LP FL+D PN KC KGG AAYS++VN+ L + + A
Sbjct: 992 GGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNIL---------------LGHGTRVGA- 1035
Query: 1065 CNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTI 1124
+ FM YH L+ S D+ +AL+ AR +A+N+T + + G+ A+ VFPY++
Sbjct: 1036 ---------TYFMTYHTVLQTSADFIDALKKARLIASNVTETMG-INGS--AYRVFPYSV 1083
Query: 1125 TNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMA 1184
VFYEQYLTI+ + +F L + L F V+ +LLG +L S ++ +I M+LV+ G M
Sbjct: 1084 FYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMW 1143
Query: 1185 LWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVA 1244
LWGIS NAVSL+NLV + G+SVEF SHITR+F +S K + +ERA+EA MGS+VF+G+
Sbjct: 1144 LWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGIT 1203
Query: 1245 MTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPA 1299
+T GI+VL AK+Q+ QIF+FR+ L + LLG HGL+FLPV+LSY+GP VN A
Sbjct: 1204 LTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKA 1258
>gi|52145305 patched 2 [Homo sapiens]
Length = 1203
Score = 110 bits (275), Expect = 9e-24
Identities = 84/275 (30%), Positives = 128/275 (46%), Gaps = 20/275 (7%)
Query: 554 LAIGGYKGKDYSE---AEALIMTF------SLNNYPAGDPRLAQAKLWEEAFLEEMRAFQ 604
L +GG E AEAL TF L + GD + EE ++A+Q
Sbjct: 297 LLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQ 356
Query: 605 RRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVI-------FLYISLALGSYSSW 657
RR + Q S + +T D + A S + L ++ A + W
Sbjct: 357 RRFVQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAARVVGGYLLMLAYACVTMLRW 416
Query: 658 SRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIF 717
S+ ++GL GV +V AV + +G + LGI + QV+PFL L +G D++F+
Sbjct: 417 D--CAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFL- 473
Query: 718 VLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSG 777
L + PG P + +G L R S++L S++ F + AL P+PA+R F+L +
Sbjct: 474 -LAHAFTEALPGTPLQERMGECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAA 532
Query: 778 LAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
+ V F+ M F A+LSLD +R+ RLDV CC
Sbjct: 533 IVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCC 567
Score = 99.4 bits (246), Expect = 2e-20
Identities = 76/215 (35%), Positives = 116/215 (53%), Gaps = 18/215 (8%)
Query: 1083 LKNSQDYTEALRAARELAANI-TADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLF 1141
L+ + D+ EA+ AR A A + P P +F+EQYL + F
Sbjct: 917 LQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPF----------LFWEQYLGL--RRCF 964
Query: 1142 MLSLC--LVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLV 1199
+L++C LV TF V LLL +GL+ +L + M+ V+ G M GI +A+ ++ LV
Sbjct: 965 LLAVCILLVCTFLVCALLLLNPWTAGLI-VLVLAMMTVELFGIMGFLGIKLSAIPVVILV 1023
Query: 1200 SAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKA 1259
++VG+ VEF H+ F ++T+ + RA A + V G A++ L G+L+L +
Sbjct: 1024 ASVGIGVEFTVHVALGF-LTTQGSRNLRAAHALEHTFAPVTDG-AISTLLGLLMLAGSHF 1081
Query: 1260 QLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1294
I +FF ++TLLGLLHGLV LPV+LS +GP
Sbjct: 1082 DFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGP 1116
Score = 35.0 bits (79), Expect = 0.49
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 4/128 (3%)
Query: 1165 GLLNLLSIVMILVDTVGFMALWGISYNAVSLINL-VSAVGMSVEFVSHITRSFAISTKPT 1223
GL +L + + + +G AL GI++NA + L A+G+ V+ V + +F + T
Sbjct: 426 GLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTEALPGT 485
Query: 1224 WL-ERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGL 1282
L ER E G++V ++ N+ L+ L ++ F + +++ + L
Sbjct: 486 PLQERMGECLQRTGTSVVL-TSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVML 544
Query: 1283 VFLPVILS 1290
VF P ILS
Sbjct: 545 VF-PAILS 551
>gi|134254450 patched isoform S [Homo sapiens]
Length = 1296
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 239 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 297
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 298 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 352
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 353 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 412
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 413 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 462
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 821 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 871
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 872 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 930
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 931 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 986
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 987 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1046
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1047 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1082
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 581 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 640
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 641 AAQFKYFSFYNMY 653
>gi|134254435 patched isoform S [Homo sapiens]
Length = 1296
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 239 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 297
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 298 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 352
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 353 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 412
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 413 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 462
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 821 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 871
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 872 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 930
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 931 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 986
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 987 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1046
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1047 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1082
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 581 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 640
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 641 AAQFKYFSFYNMY 653
>gi|134254468 patched isoform S [Homo sapiens]
Length = 1296
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 239 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 297
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 298 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 352
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 353 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 412
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 413 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 462
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 821 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 871
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 872 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 930
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 931 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 986
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 987 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1046
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1047 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1082
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 581 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 640
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 641 AAQFKYFSFYNMY 653
>gi|134254452 patched isoform S [Homo sapiens]
Length = 1296
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 239 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 297
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 298 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 352
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 353 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 412
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 413 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 462
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 821 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 871
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 872 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 930
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 931 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 986
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 987 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1046
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1047 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1082
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 581 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 640
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 641 AAQFKYFSFYNMY 653
>gi|134254432 patched isoform L' [Homo sapiens]
Length = 1446
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 389 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 447
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 448 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 502
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 503 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 562
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 563 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 612
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 971 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 1021
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 1022 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 1080
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 1081 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 1136
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 1137 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1196
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1197 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1232
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 731 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 790
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 791 AAQFKYFSFYNMY 803
>gi|134254466 patched isoform M [Homo sapiens]
Length = 1381
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 324 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 382
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 383 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 437
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 438 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 497
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 498 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 547
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 906 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 956
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 957 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 1015
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 1016 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 1071
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 1072 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1131
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1132 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1167
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 666 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 725
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 726 AAQFKYFSFYNMY 738
>gi|134254446 patched isoform L [Homo sapiens]
Length = 1447
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 390 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 448
Query: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 449 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 503
Query: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 504 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 563
Query: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 564 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
Score = 103 bits (256), Expect = 1e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 972 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 1022
Query: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 1023 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 1081
Query: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 1082 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 1137
Query: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 1138 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1197
Query: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
E + V A P H S +D+ +S + ++ G
Sbjct: 1198 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1233
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLD-- 885
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D
Sbjct: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
Query: 886 -----YFLFLNRY 893
YF F N Y
Sbjct: 792 AAQFKYFSFYNMY 804
>gi|194018513 patched domain containing 3 [Homo sapiens]
Length = 767
Score = 99.4 bits (246), Expect = 2e-20
Identities = 130/598 (21%), Positives = 244/598 (40%), Gaps = 85/598 (14%)
Query: 336 LLGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFT--ELTTDPVELWSAPNSQARSE 393
LL + FQ G V + P L+ ++ AL G ++ + D E ++ S A++E
Sbjct: 122 LLSRTFQWLGWQVGAHPWIFLLAPLMLTAALGTGFLYLPKDEEEDLEEHYTPVGSPAKAE 181
Query: 394 KAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFS-GILDLDLLLELLELQERLR 452
+ F HF TN + +R S + + L ++S +LD E+ +L ++
Sbjct: 182 RRFVQGHF----TTNDSYRFSASRRSTEANFVSLLVVSYSDSLLDPATFAEVSKLDGAVQ 237
Query: 453 HLQVWSPEAQRNISLQDIC--YAPLNPDNTSLYDCCI--NSLLQYFQNNRTLLLLTANQT 508
L+V + E I Q +C Y L C+ N +L +Q N+TL L + +
Sbjct: 238 DLRV-AREKGSQIQYQQVCARYRAL----------CVPPNPILYAWQVNKTLNLSSISFP 286
Query: 509 LMGQTSQVDWKDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAE 568
H LY + G +L + G+ A+
Sbjct: 287 AYNHGR------HPLYLTGFFGGYILGGSLGM--------------------GQLLLRAK 320
Query: 569 ALIMTFSLNNYPAGDPRL-AQAKLWEEAFLEEMRAFQRRMA-GMFQVTFMAERSLEDEIN 626
A+ + + L DP Q+K W L++ + +A +V S + E
Sbjct: 321 AMRLLYYLKTE---DPEYDVQSKQWLTHLLDQFTNIKNILALKKIEVVHFTSLSRQLEFE 377
Query: 627 RTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGF 686
T+ +P+F +YI+I L+ + + + +K + GV AV++ G
Sbjct: 378 ATSVTVIPVFHLAYILIILFAVTSCFRFDC-----IRNKMCVAAFGVISAFLAVVSGFGL 432
Query: 687 FSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPS 746
++G+ ++I+ PFL+L VG D++FI + + + + RE + + A S
Sbjct: 433 LLHIGV-PFVIIVANSPFLILGVGVDDMFIMISAWHKT-NLADDIRE-RMSNVYSKAAVS 489
Query: 747 MLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASR 806
+ + +++ + + G ++ +V+ F + +G+ ++ + ++ F A ++LD KR+
Sbjct: 490 ITITTITNILALYTGIMSSFRSVQCFCIYTGMTLLFCYFYNITCFGAFMALDGKREV--- 546
Query: 807 LDVCCCVKPQELP----------------PPGQGEGL--LLGFFQKAYAPFLLHWITRGV 848
VC C + P P G + + FF+ + PFL ++
Sbjct: 547 --VCLCWLKKADPKWPSFKKFCCFPFGSVPDEHGTDIHPISLFFRDYFGPFLTRSESKYF 604
Query: 849 VLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYF-EVGAPVYFVTT 905
V+ +++ S+Y H+ GLD DSY+ YF YF + G V + T
Sbjct: 605 VVFIYVLYIISSIYGCFHVQEGLDLRNLASDDSYITPYFNVEENYFSDYGPRVMVIVT 662
>gi|148277106 hypothetical protein LOC442213 [Homo sapiens]
Length = 829
Score = 95.9 bits (237), Expect = 2e-19
Identities = 173/803 (21%), Positives = 310/803 (38%), Gaps = 155/803 (19%)
Query: 560 KGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAER 619
K + A A+ +T+ L Y + L K WE F + +R Q + Q+ +A
Sbjct: 146 KDQRVKSARAIQITYYLQTYGSATQDLIGEK-WENEFCKLIRKLQEEHQEL-QLYSLASF 203
Query: 620 SLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGA 679
SL + ++T+ I A S +++ L + L + SS + + SK LGL GV V +
Sbjct: 204 SLWRDFHKTS-----ILARSKVLVSLVLILTTATLSSSMKDCLRSKPFLGLLGVLTVCIS 258
Query: 680 VMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRA 739
++ A G F + + +L +PF + G +F + ++R + P + I A
Sbjct: 259 IITAAGIFFITDGKYNSTLLG-IPFFAMGHGTKGVFELLSGWRR--TKENLPFKDRIADA 315
Query: 740 LGRVAPSMLLCSLSEAICFFLGA--LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSL 797
V + + S I F +GA T + AV+ F ++++L++ S F + L
Sbjct: 316 YSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKVFCQNMCVSILLNYFYIFSFFGSCLVF 375
Query: 798 DSKRQEASRLDVCCCVKP------------QELPPPGQGE-----------GLLLGFFQK 834
+ ++ + CC P Q + G + + F ++
Sbjct: 376 AGQLEQNRYHSIFCCKIPSAEYLDRKPVWFQTVMSDGHQQTSHHETNPYQHHFIQHFLRE 435
Query: 835 AYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYF 894
Y ++ + + V++L+L S IS G + L DS + Y + +YF
Sbjct: 436 HYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGANIINLLASDSPSVSYAMVQQKYF 495
Query: 895 EVGAPV---YFVTTLGY-NFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPA 950
+PV Y L Y N S + + +CS FT A
Sbjct: 496 SNYSPVIGFYVYEPLEYWNSSVQDDLRRLCS-------GFT------------------A 530
Query: 951 SSWVDDFIDWLTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHK 1010
SWV+ + +L S+ +S NK F +S+ S E H
Sbjct: 531 VSWVEQYYQFLKVSN-----VSANNKSDF--------------ISVLQSSFLKKPEFQH- 570
Query: 1011 YLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLL 1070
F ND I S + S I++ LYL+
Sbjct: 571 ----FRND------------------------------IIFSKAGDESNIIAS--RLYLV 594
Query: 1071 DSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYE 1130
TSR ++ TE L R L +++ +R + +P+F VF +
Sbjct: 595 ARTSR--------DKQKEITEVLEKLRPL--SLSKSIRFIV-FNPSF---------VFMD 634
Query: 1131 QY-----LTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMAL 1185
Y + +L G F + L L+ TF + LG +LS+ I + +G M L
Sbjct: 635 HYSLSVTVPVLIAG-FGVLLVLILTFFLVIHPLG-----NFWLILSVTSIELGVLGLMTL 688
Query: 1186 WGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAM 1245
W + + +S++ L+ + +++ + + +F ++T+ T + K + G+A+ V
Sbjct: 689 WNVDMDCISILCLIYTLNFAIDHCAPLLFTFVLATEHTRTQCIKSSLQDHGTAILQNVT- 747
Query: 1246 TNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDV--NPALALE 1303
+ L G++ L + L F+ LL LLH V LPV L++ P +
Sbjct: 748 SFLIGLVPLLFVPSNL-TFTLFKCLLLTGGCTLLHCFVILPVFLTFFPPSKKHHKKKKRA 806
Query: 1304 QKRAEEAVAAVMVASCPNHPSRV 1326
+++ E + + + P+H + V
Sbjct: 807 KRKEREEIECIEIQENPDHVTTV 829
>gi|66932902 SREBF chaperone protein [Homo sapiens]
Length = 1279
Score = 74.3 bits (181), Expect = 7e-13
Identities = 54/192 (28%), Positives = 98/192 (51%), Gaps = 17/192 (8%)
Query: 630 AEDLPIFATSYIVIFLYISLALGSYSSWSRV-MVDSKATLGLGGVAVVLGAVMAAMGFFS 688
AE +P+ T+YI++F YI Y S ++ MV SK L L V VL +++ ++G +
Sbjct: 283 AELIPL-VTTYIILFAYI------YFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCT 335
Query: 689 YLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSML 748
G+ +L ++ P+LV+ +G +N+ + P ++ I + L + S++
Sbjct: 336 LFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTP--VDLEVKLRIAQGLSSESWSIM 393
Query: 749 LCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLD 808
+E +G T +PA++ F L + + ++ DF LQM F +LS+D +R E + L+
Sbjct: 394 KNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLN 453
Query: 809 VCCCVKPQELPP 820
+ LPP
Sbjct: 454 -------KRLPP 458
>gi|148271104 patched domain containing 1 [Homo sapiens]
Length = 888
Score = 70.1 bits (170), Expect = 1e-11
Identities = 135/601 (22%), Positives = 237/601 (39%), Gaps = 86/601 (14%)
Query: 334 HTLLGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSE 393
H L F G ++AS P+ V+ + L A ++ L + +S A+ E
Sbjct: 7 HRGLRTCFSRLGHFIASHPVFFASAPVLISILLGASFSRYQVEESVEHLLAPQHSLAKIE 66
Query: 394 KAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRH 453
+ + F P R+ L + ++ RY +++ + +LD +L+L +
Sbjct: 67 RNLVNSLF-PVNRSKHR-LYSDLQTPGRYGRVIVTSFQKANMLDQHHTDLILKLHAAVTK 124
Query: 454 LQVWSPEAQRNISLQDICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQT 513
+QV P N + IC LN D T + D ++ +L+ +N R N+T T
Sbjct: 125 IQV--PRPGFNYTFAHICI--LNNDKTCIVDDIVH-VLEELKNARA-----TNRTNFAIT 174
Query: 514 SQVDWKDHFLYCANAPLT-FKDGTALALSCMADYGAPVFPFLAIGGYK--GKD-YSEAEA 569
P+T KDG A V+ +GG KD AEA
Sbjct: 175 Y--------------PITHLKDGRA------------VYNGHQLGGVTVHSKDRVKSAEA 208
Query: 570 LIMTFSLNNYPAGDPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTT 629
+ +T+ L + + + +A+ WE +F + +R FQ+ + + + + SL ++ +T+
Sbjct: 209 IQLTYYLQSINSLNDMVAER--WESSFCDTVRLFQKSNSKVKMYPYTSS-SLREDFQKTS 265
Query: 630 AEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSY 689
TS I++ L V SK LGL G+ + A + A G +
Sbjct: 266 RVSERYLVTSLILVVTMAILCCSMQDC-----VRSKPWLGLLGLVTISLATLTAAGIINL 320
Query: 690 LGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLL 749
G + + L V PF++L G F + + R+ E + V R A SML
Sbjct: 321 TGGKYNSTFLGV-PFVMLGHGLYGTFEMLSSW----RKTREDQHVK-ERTAAVYADSMLS 374
Query: 750 CSLSEA---ICFFLGA--LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEA 804
SL+ A + F +GA T + A R F S +A+ ++L +S + + L +
Sbjct: 375 FSLTTAMYLVTFGIGASPFTNIEAARIFCCNSCIAIFFNYLYVLSFYGSSLVFTGYIENN 434
Query: 805 SRLDVCCCVKP-----QELPP-------------PGQGEG-------LLLGFFQKAYAPF 839
+ + C P QE P +GE LL+ F ++ Y +
Sbjct: 435 YQHSIFCRKVPKPEALQEKPAWYRFLLTARFSEDTAEGEEANTYESHLLVCFLKRYYCDW 494
Query: 840 LLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAP 899
+ + + V+L +L +L +S G D + + ++Y +YF +P
Sbjct: 495 ITNTYVKPFVVLFYLIYISFALMGYLQVSEGSDLSNIVATATQTIEYTTAQQKYFSNYSP 554
Query: 900 V 900
V
Sbjct: 555 V 555
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 1170 LSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAIS---TKPTWLE 1226
L++V + +GFM LW + + +S++ L+ + +++ + + +F + T+ W++
Sbjct: 729 LTVVSVEFGVIGFMTLWKVELDCISVLCLIYGINYTIDNCAPMLSTFVLGKDFTRTKWVK 788
Query: 1227 RAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLP 1286
A E G A+ + + G++ L + L FR LI + H LP
Sbjct: 789 NALEV---HGVAILQSY-LCYIVGLIPLAAVPSNL-TCTLFRCLFLIAFVTFFHCFAILP 843
Query: 1287 VILSYVGP 1294
VIL+++ P
Sbjct: 844 VILTFLPP 851
Score = 33.9 bits (76), Expect = 1.1
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 1118 EVFPYTITNVFYE-QYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRS----GLLNLLSI 1172
+++PYT +++ + Q + + E + SL LV T A+ C + +RS GLL L++I
Sbjct: 248 KMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDCVRSKPWLGLLGLVTI 307
Query: 1173 VMILVDTVGFMALWGISYNAVSL 1195
+ + G + L G YN+ L
Sbjct: 308 SLATLTAAGIINLTGGKYNSTFL 330
>gi|149274653 patched domain containing 2 [Homo sapiens]
Length = 1392
Score = 49.3 bits (116), Expect = 3e-05
Identities = 58/256 (22%), Positives = 106/256 (41%), Gaps = 24/256 (9%)
Query: 576 LNNYPAGDPRLAQAKLWEEAFLEEMRAF-QRRMAGMFQVTFMAERSLEDEINRTTAED-- 632
L NY + D R + + ++F+ A ++ QV + + E+ RT D
Sbjct: 405 LPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDML 464
Query: 633 LPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGI 692
L ++S I +YI + + S+ G ++ L ++A + GI
Sbjct: 465 LAFISSSCIAALVYILTSCSVFLSF------------FGIASIGLSCLVALFLYHVVFGI 512
Query: 693 RSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPR-RPGEPREVHIGRALGRVAPSMLLCS 751
+ ++ V F+++ +G D++F+F+ Y++ + R +H + G+ + S
Sbjct: 513 QYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTVQTAGK---ATFFTS 569
Query: 752 LSEAICFFLGALTPMPAVRTFALTSGLAVI---LDFLLQMSAFVALLSLDSKRQEASRLD 808
L+ A + + +PAV F L L V L L+ M A + L SL E+S
Sbjct: 570 LTTAAAYAANVFSQIPAVHDFGLFMSLIVSCCWLAVLVTMPAALGLWSLYLAPLESSCQT 629
Query: 809 VC--CCVKPQELPPPG 822
C C + L PG
Sbjct: 630 SCHQNCSRKTSLHFPG 645
>gi|25121980 dispatched B [Homo sapiens]
Length = 1401
Score = 45.8 bits (107), Expect = 3e-04
Identities = 43/179 (24%), Positives = 75/179 (41%), Gaps = 6/179 (3%)
Query: 1077 MAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTIL 1136
+ + +NS DY + E++ + A+L P P +T Y ++
Sbjct: 905 LQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAP---PGLRRGWFTSRLELYSLQHSLS 961
Query: 1137 PEGLFMLSLCLVPTFAVSCLLLGL-DLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSL 1195
E +L L L FA LLLG ++ L ++ ++ ++ TVG + L N
Sbjct: 962 TEPAVVLGLALALAFAT--LLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEA 1019
Query: 1196 INLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVL 1254
+ L ++VG+SV+F + S+ + P L R + A G A G+L+L
Sbjct: 1020 LFLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLML 1078
Score = 38.5 bits (88), Expect = 0.044
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 12/149 (8%)
Query: 642 VIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQV 701
++ ++ +AL S + +MV LG VA L V M +F ++ + + L
Sbjct: 496 LVAIFFGMALYLRSLFLTLMV-LLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALL----- 549
Query: 702 VPFLVLSVGADNIFIFVLEYQRLPRR--PGEPREVHIGRALGRVAPSMLLCSLSEAICFF 759
L+ SV A++ IF + RL + P +GR + +L+ L+ + F+
Sbjct: 550 ---LLSSVCANHTLIF-FDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFY 605
Query: 760 LGALTPMPAVRTFALTSGLAVILDFLLQM 788
L+ +PAVR AL G AV++ L +
Sbjct: 606 ASYLSRLPAVRCLALFMGTAVLVHLALTL 634
>gi|25952134 dispatched A [Homo sapiens]
Length = 1524
Score = 41.2 bits (95), Expect = 0.007
Identities = 37/167 (22%), Positives = 71/167 (42%), Gaps = 3/167 (1%)
Query: 1128 FYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWG 1187
FY+ ++ L + L + F+V LL ++ L ++SI + TVG + L G
Sbjct: 973 FYDLQDSLSDGTLIAMGLSVAVAFSVM-LLTTWNIIISLYAIISIAGTIFVTVGSLVLLG 1031
Query: 1188 ISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTN 1247
N + + + AVG+SV+F H ++ ++ P + + +GSA+ T
Sbjct: 1032 WELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRVGSAMAMAALTTF 1091
Query: 1248 LPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1294
+ G +++ Q+ F +LI + F + +GP
Sbjct: 1092 VAGAMMMPSTVLAYTQLGTFM--MLIMCISWAFATFFFQCMCRCLGP 1136
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 40.8 bits (94), Expect = 0.009
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 1003 PSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTIS 1062
P+ YL DR N+ K L + S L ++G V++LSPRL+ SG IS
Sbjct: 57 PAARHLAVYLLDHFMDRYNVTTSKQ-LYTVAVSCLLLANG-----VSLLSPRLKCSGMIS 110
Query: 1063 AHCNLYLL-DSTSRFMAYHKP 1082
AHCNL+L S S A H P
Sbjct: 111 AHCNLHLPGSSNSPASAPHPP 131
>gi|58331120 hypothetical protein LOC29058 isoform 1 [Homo sapiens]
Length = 183
Score = 40.4 bits (93), Expect = 0.012
Identities = 20/32 (62%), Positives = 23/32 (71%)
Query: 1042 GQVLDTVAILSPRLEYSGTISAHCNLYLLDST 1073
G L +LSPRLE SG ISAHCNL+LL S+
Sbjct: 19 GAALRWSLVLSPRLEPSGVISAHCNLHLLASS 50
>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
sapiens]
Length = 1151
Score = 38.9 bits (89), Expect = 0.034
Identities = 16/26 (61%), Positives = 23/26 (88%)
Query: 1049 AILSPRLEYSGTISAHCNLYLLDSTS 1074
+++SPRLE SGT+ AHC+L LLDS++
Sbjct: 438 SVMSPRLECSGTVIAHCSLKLLDSSN 463
>gi|187608508 centromere protein L isoform 1 [Homo sapiens]
Length = 390
Score = 37.4 bits (85), Expect = 0.099
Identities = 18/24 (75%), Positives = 19/24 (79%)
Query: 1050 ILSPRLEYSGTISAHCNLYLLDST 1073
ILSPRLEYSGTI CNL LL S+
Sbjct: 143 ILSPRLEYSGTILVDCNLCLLGSS 166
>gi|239744440 PREDICTED: hypothetical protein XP_002343124 [Homo
sapiens]
Length = 261
Score = 36.2 bits (82), Expect = 0.22
Identities = 17/23 (73%), Positives = 19/23 (82%)
Query: 1051 LSPRLEYSGTISAHCNLYLLDST 1073
L PRLE+SGTISA CNL LL S+
Sbjct: 10 LYPRLEFSGTISARCNLRLLGSS 32
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [Homo
sapiens]
Length = 759
Score = 35.8 bits (81), Expect = 0.29
Identities = 16/22 (72%), Positives = 19/22 (86%)
Query: 1052 SPRLEYSGTISAHCNLYLLDST 1073
SPRLE SG ISAHC+L+L DS+
Sbjct: 6 SPRLECSGAISAHCSLHLPDSS 27
>gi|28372523 intraflagellar transport protein IFT20 [Homo sapiens]
Length = 148
Score = 35.8 bits (81), Expect = 0.29
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 1027 GGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDST 1073
GGL + ++ + + ++A+ SPRLE +G ISAHC L L DS+
Sbjct: 52 GGLIELVDQLAKEAENEKMKSLAV-SPRLECTGAISAHCKLCLSDSS 97
>gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]
Length = 226
Score = 35.4 bits (80), Expect = 0.37
Identities = 20/40 (50%), Positives = 24/40 (60%), Gaps = 6/40 (15%)
Query: 1051 LSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYT 1090
LSPRLE +G ISAHCNL L S+ + P SQ +T
Sbjct: 61 LSPRLERNGMISAHCNLCLTGSS------NSPASASQAFT 94
>gi|239755619 PREDICTED: hypothetical protein [Homo sapiens]
Length = 261
Score = 35.4 bits (80), Expect = 0.37
Identities = 16/21 (76%), Positives = 18/21 (85%)
Query: 1053 PRLEYSGTISAHCNLYLLDST 1073
PRLE+SGTISA CNL LL S+
Sbjct: 12 PRLEFSGTISARCNLRLLGSS 32
>gi|239750132 PREDICTED: hypothetical protein XP_002347267 [Homo
sapiens]
Length = 261
Score = 35.4 bits (80), Expect = 0.37
Identities = 16/21 (76%), Positives = 18/21 (85%)
Query: 1053 PRLEYSGTISAHCNLYLLDST 1073
PRLE+SGTISA CNL LL S+
Sbjct: 12 PRLEFSGTISARCNLRLLGSS 32
>gi|237858664 hypothetical protein LOC123207 isoform b [Homo sapiens]
Length = 167
Score = 35.4 bits (80), Expect = 0.37
Identities = 15/23 (65%), Positives = 19/23 (82%)
Query: 1051 LSPRLEYSGTISAHCNLYLLDST 1073
LSP+LE SG + AHCNL+LL S+
Sbjct: 138 LSPKLECSGVVLAHCNLHLLGSS 160
>gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]
Length = 629
Score = 34.7 bits (78), Expect = 0.64
Identities = 16/24 (66%), Positives = 20/24 (83%)
Query: 1051 LSPRLEYSGTISAHCNLYLLDSTS 1074
L PRLE S TI+AHC+L LLDS++
Sbjct: 588 LWPRLECSSTITAHCSLNLLDSSN 611
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,145,930
Number of Sequences: 37866
Number of extensions: 2212121
Number of successful extensions: 6492
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 6359
Number of HSP's gapped (non-prelim): 92
length of query: 1359
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1244
effective length of database: 13,892,928
effective search space: 17282802432
effective search space used: 17282802432
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.