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Search of human proteins with 156104895
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156104895 inositol polyphosphate-4-phosphatase, type II,
105kD [Homo sapiens]
(924 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105k... 1854 0.0
gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105k... 1854 0.0
gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform ... 738 0.0
gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isofor... 737 0.0
gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isofor... 734 0.0
gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform ... 672 0.0
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 108 3e-23
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R... 98 4e-20
gi|88703066 copine-like protein [Homo sapiens] 39 0.029
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 37 0.11
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 35 0.42
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 35 0.42
gi|22748811 hypothetical protein LOC127795 [Homo sapiens] 35 0.42
gi|28872803 myeloid translocation gene on chromosome 16 isoform ... 33 1.6
gi|28872805 myeloid translocation gene on chromosome 16 isoform ... 33 1.6
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 33 1.6
gi|217416374 hypothetical protein LOC92749 [Homo sapiens] 32 2.1
gi|46488923 astrotactin isoform 1 [Homo sapiens] 32 2.7
gi|46488921 astrotactin isoform 2 [Homo sapiens] 32 2.7
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 32 3.6
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo... 31 4.7
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 31 4.7
gi|68508961 centromere protein C 1 [Homo sapiens] 31 4.7
gi|125625357 Sp2 transcription factor [Homo sapiens] 31 4.7
gi|42794779 myosin 18A isoform b [Homo sapiens] 31 4.7
gi|28416946 myosin 18A isoform a [Homo sapiens] 31 4.7
gi|42558250 membrane component chromosome 11 surface marker 1 is... 31 4.7
gi|42734503 membrane component chromosome 11 surface marker 1 is... 31 4.7
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 31 6.1
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H... 31 6.1
>gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105kD
[Homo sapiens]
Length = 924
Score = 1854 bits (4802), Expect = 0.0
Identities = 924/924 (100%), Positives = 924/924 (100%)
Query: 1 MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLN 60
MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLN
Sbjct: 1 MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLN 60
Query: 61 TLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDK 120
TLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDK
Sbjct: 61 TLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDK 120
Query: 121 SHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIE 180
SHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIE
Sbjct: 121 SHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIE 180
Query: 181 VSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYR 240
VSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYR
Sbjct: 181 VSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYR 240
Query: 241 FPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV 300
FPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV
Sbjct: 241 FPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV 300
Query: 301 LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDAL 360
LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDAL
Sbjct: 301 LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDAL 360
Query: 361 YDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL 420
YDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL
Sbjct: 361 YDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL 420
Query: 421 QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGG 480
QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGG
Sbjct: 421 QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGG 480
Query: 481 ILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVD 540
ILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVD
Sbjct: 481 ILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVD 540
Query: 541 KLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ 600
KLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ
Sbjct: 541 KLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ 600
Query: 601 SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVG 660
SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVG
Sbjct: 601 SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVG 660
Query: 661 LIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVK 720
LIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVK
Sbjct: 661 LIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVK 720
Query: 721 LPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEY 780
LPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEY
Sbjct: 721 LPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEY 780
Query: 781 YKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT 840
YKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT
Sbjct: 781 YKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT 840
Query: 841 CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF 900
CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF
Sbjct: 841 CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF 900
Query: 901 NMLQLMAFPKYYRPPEGTYGKADT 924
NMLQLMAFPKYYRPPEGTYGKADT
Sbjct: 901 NMLQLMAFPKYYRPPEGTYGKADT 924
>gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105kD
[Homo sapiens]
Length = 924
Score = 1854 bits (4802), Expect = 0.0
Identities = 924/924 (100%), Positives = 924/924 (100%)
Query: 1 MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLN 60
MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLN
Sbjct: 1 MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLN 60
Query: 61 TLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDK 120
TLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDK
Sbjct: 61 TLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDK 120
Query: 121 SHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIE 180
SHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIE
Sbjct: 121 SHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIE 180
Query: 181 VSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYR 240
VSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYR
Sbjct: 181 VSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYR 240
Query: 241 FPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV 300
FPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV
Sbjct: 241 FPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV 300
Query: 301 LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDAL 360
LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDAL
Sbjct: 301 LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDAL 360
Query: 361 YDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL 420
YDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL
Sbjct: 361 YDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL 420
Query: 421 QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGG 480
QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGG
Sbjct: 421 QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGG 480
Query: 481 ILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVD 540
ILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVD
Sbjct: 481 ILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVD 540
Query: 541 KLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ 600
KLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ
Sbjct: 541 KLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ 600
Query: 601 SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVG 660
SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVG
Sbjct: 601 SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVG 660
Query: 661 LIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVK 720
LIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVK
Sbjct: 661 LIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVK 720
Query: 721 LPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEY 780
LPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEY
Sbjct: 721 LPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEY 780
Query: 781 YKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT 840
YKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT
Sbjct: 781 YKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT 840
Query: 841 CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF 900
CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF
Sbjct: 841 CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF 900
Query: 901 NMLQLMAFPKYYRPPEGTYGKADT 924
NMLQLMAFPKYYRPPEGTYGKADT
Sbjct: 901 NMLQLMAFPKYYRPPEGTYGKADT 924
>gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform a
[Homo sapiens]
Length = 938
Score = 738 bits (1905), Expect = 0.0
Identities = 415/921 (45%), Positives = 584/921 (63%), Gaps = 55/921 (5%)
Query: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95
P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+
Sbjct: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
Query: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155
+ F + I + T++KL+VYDVKD+S T+ LG +F V +L
Sbjct: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
Query: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214
L+ + L L+LR+++ +V G I V +M E D + D + L + +
Sbjct: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
Query: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266
E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+
Sbjct: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
Query: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326
+ + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF
Sbjct: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
Query: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386
K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
Query: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439
+FE +++ +G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S
Sbjct: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
Query: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497
L+ +L +L++KT V +L+ +++ L ARP I K SP S+ EE
Sbjct: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
Query: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDGGSEGSG 553
DQ +M G++S D+ EEEW++VW NV KSL CII VDKL++++ G G
Sbjct: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKER-LHGEG 558
Query: 554 GNNDGEKEPSLT---DAIPSHPRE----DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVL 606
+ S T D P P E +W E LYPL+ TL DC+ + ++AK+++ F+L
Sbjct: 559 CEDVFPCAGSCTSKKDCSPP-PEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLL 617
Query: 607 LQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYE 666
+Q+ A ++ L L RRD+VF Q L L+CGFIIKL+ L+D GFL+QL+T+GL+ Q+E
Sbjct: 618 MQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFE 677
Query: 667 GLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSN---DVLPVITGRREHYVVEVKLPA 723
LLSTY +E+ MLEDM++GI DL+ V FK+ +A S+ D+LPVITG R+ + V V LP
Sbjct: 678 SLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPG 737
Query: 724 RMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYYKI 783
+F++LP +I+ G LL V PVLFNVGINEQQTLAERFGD SLQE IN E+ L Y++
Sbjct: 738 PLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQ 797
Query: 784 FMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCK 843
F E +P D + + Q L LL L QN+ ++K KNV+I+W AA ICR+LNG+RFT CK
Sbjct: 798 FKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCK 857
Query: 844 SAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNML 903
SAKDRT+MSVTLEQC IL+ EH + F +AL+CMR EGCR EN +KN+ RKYAFN L
Sbjct: 858 SAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSL 917
Query: 904 QLMAFPKYYRPPEGTYGKADT 924
QL AFPK+YRPPEGTYGK +T
Sbjct: 918 QLKAFPKHYRPPEGTYGKVET 938
>gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isoform c
[Homo sapiens]
Length = 972
Score = 737 bits (1903), Expect = 0.0
Identities = 417/953 (43%), Positives = 584/953 (61%), Gaps = 85/953 (8%)
Query: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95
P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+
Sbjct: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
Query: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155
+ F + I + T++KL+VYDVKD+S T+ LG +F V +L
Sbjct: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
Query: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214
L+ + L L+LR+++ +V G I V +M E D + D + L + +
Sbjct: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
Query: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266
E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+
Sbjct: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
Query: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326
+ + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF
Sbjct: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
Query: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386
K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
Query: 387 RFETERRNT--GYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHSPDSLK 444
+FE +++T G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S L+
Sbjct: 381 KFEETKKHTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLE 440
Query: 445 NSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP--QDQPP 502
+L +L++KT V +L+ +++ L ARP I K SP S+ EE DQ
Sbjct: 441 RTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLRNDQDT 499
Query: 503 VMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERD------------ 546
+M G++S D+ EEEW++VW NV KSL CII VDKL++++
Sbjct: 500 LMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGCEDVFP 559
Query: 547 --GGSEGSGGNNDGEK--------------------------EPSLTDAIPSHPRE---- 574
G GN D P LT P E
Sbjct: 560 CAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPEESSPG 619
Query: 575 DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAG 634
+W E LYPL+ TL DC+ + ++AK+++ F+L+Q+ A ++ L L RRD+VF Q L
Sbjct: 620 EWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTA 679
Query: 635 LVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAF 694
L+CGFIIKL+ L+D GFL+QL+T+GL+ Q+E LLSTY +E+ MLEDM++GI DL+ V F
Sbjct: 680 LICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTF 739
Query: 695 KIIEAKSN---DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGIN 751
K+ +A S+ D+LPVITG R+ + V V LP +F++LP +I+ G LL V PVLFNVGIN
Sbjct: 740 KVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGIN 799
Query: 752 EQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLLQ 811
EQQTLAERFGD SLQE IN E+ L Y++ F E +P D + + Q L LL L Q
Sbjct: 800 EQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQ 859
Query: 812 NIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDF 871
N+ ++K KNV+I+W AA ICR+LNG+RFT CKSAKDRT+MSVTLEQC IL+ EH +
Sbjct: 860 NVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQV 919
Query: 872 FIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT 924
F +AL+CMR EGCR EN +KN+ RKYAFN LQL AFPK+YRPPEGTYGK +T
Sbjct: 920 FTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET 972
>gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isoform d
[Homo sapiens]
Length = 977
Score = 734 bits (1894), Expect = 0.0
Identities = 416/958 (43%), Positives = 584/958 (60%), Gaps = 90/958 (9%)
Query: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95
P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+
Sbjct: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
Query: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155
+ F + I + T++KL+VYDVKD+S T+ LG +F V +L
Sbjct: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
Query: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214
L+ + L L+LR+++ +V G I V +M E D + D + L + +
Sbjct: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
Query: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266
E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+
Sbjct: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
Query: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326
+ + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF
Sbjct: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
Query: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386
K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
Query: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439
+FE +++ +G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S
Sbjct: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
Query: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497
L+ +L +L++KT V +L+ +++ L ARP I K SP S+ EE
Sbjct: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
Query: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERD------- 546
DQ +M G++S D+ EEEW++VW NV KSL CII VDKL++++
Sbjct: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGC 559
Query: 547 -------GGSEGSGGNNDGEK--------------------------EPSLTDAIPSHPR 573
G GN D P LT P
Sbjct: 560 EDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPE 619
Query: 574 E----DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFS 629
E +W E LYPL+ TL DC+ + ++AK+++ F+L+Q+ A ++ L L RRD+VF
Sbjct: 620 ESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFC 679
Query: 630 QALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDL 689
Q L L+CGFIIKL+ L+D GFL+QL+T+GL+ Q+E LLSTY +E+ MLEDM++GI DL
Sbjct: 680 QTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDL 739
Query: 690 KKVAFKIIEAKSN---DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLF 746
+ V FK+ +A S+ D+LPVITG R+ + V V LP +F++LP +I+ G LL V PVLF
Sbjct: 740 RNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLF 799
Query: 747 NVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALL 806
NVGINEQQTLAERFGD SLQE IN E+ L Y++ F E +P D + + Q L LL
Sbjct: 800 NVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELL 859
Query: 807 ENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQ 866
L QN+ ++K KNV+I+W AA ICR+LNG+RFT CKSAKDRT+MSVTLEQC IL+ EH
Sbjct: 860 RFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHG 919
Query: 867 LHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT 924
+ F +AL+CMR EGCR EN +KN+ RKYAFN LQL AFPK+YRPPEGTYGK +T
Sbjct: 920 MAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET 977
>gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform b
[Homo sapiens]
Length = 954
Score = 672 bits (1734), Expect = 0.0
Identities = 387/890 (43%), Positives = 553/890 (62%), Gaps = 55/890 (6%)
Query: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95
P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+
Sbjct: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
Query: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155
+ F + I + T++KL+VYDVKD+S T+ LG +F V +L
Sbjct: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
Query: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214
L+ + L L+LR+++ +V G I V +M E D + D + L + +
Sbjct: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
Query: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266
E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+
Sbjct: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
Query: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326
+ + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF
Sbjct: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
Query: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386
K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
Query: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439
+FE +++ +G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S
Sbjct: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
Query: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497
L+ +L +L++KT V +L+ +++ L ARP I K SP S+ EE
Sbjct: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
Query: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDGGSEGSG 553
DQ +M G++S D+ EEEW++VW NV KSL CII VDKL++++ G G
Sbjct: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKER-LHGEG 558
Query: 554 GNNDGEKEPSLT---DAIPSHPRE----DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVL 606
+ S T D P P E +W E LYPL+ TL DC+ + ++AK+++ F+L
Sbjct: 559 CEDVFPCAGSCTSKKDCSPP-PEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLL 617
Query: 607 LQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYE 666
+Q+ A ++ L L RRD+VF Q L L+CGFIIKL+ L+D GFL+QL+T+GL+ Q+E
Sbjct: 618 MQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFE 677
Query: 667 GLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSN---DVLPVITGRREHYVVEVKLPA 723
LLSTY +E+ MLEDM++GI DL+ V FK+ +A S+ D+LPVITG R+ + V V LP
Sbjct: 678 SLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPG 737
Query: 724 RMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYYKI 783
+F++LP +I+ G LL V PVLFNVGINEQQTLAERFGD SLQE IN E+ L Y++
Sbjct: 738 PLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQ 797
Query: 784 FMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCK 843
F E +P D + + Q L LL L QN+ ++K KNV+I+W AA ICR+LNG+RFT CK
Sbjct: 798 FKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCK 857
Query: 844 SAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNI 893
SAKDRT+MSVTLEQC IL+ EH + F +AL+CMR G R KN+
Sbjct: 858 SAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907
>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
Length = 1606
Score = 108 bits (269), Expect = 3e-23
Identities = 105/389 (26%), Positives = 176/389 (45%), Gaps = 59/389 (15%)
Query: 559 EKEPSLT--DAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQ 616
E EP L+ + H ++D + L + TL + + V K L LL+ YS +
Sbjct: 1203 EMEPKLSCPKRLRLHIKQDPWN-LPSSVRTLAQNIRKFVEEVKCRLLLALLE---YSDSE 1258
Query: 617 CLMLTLRRDIVFSQALAGLVCGFIIKLQTSL---YDPG-------------FLQQLHTVG 660
LRRD+VF Q L VC F +L +L +D +L Q+ G
Sbjct: 1259 T---QLRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAG 1315
Query: 661 LIVQYEGLLS-TYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVIT------GRRE 713
++ ++ LLS +DE MLED V + DL+KV+F ++ ++ + G R+
Sbjct: 1316 VLFHFQSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQ 1375
Query: 714 HYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQE---SIN 770
V + + FE LP ++K G ++PVLF + + R +VS++E IN
Sbjct: 1376 ALKVYFYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYR-DNVSVEEFQAQIN 1434
Query: 771 QENFELLQEYYK----IFMEKM--PPDYISH-------FQEQNDLKALLENLLQNIQSKK 817
+ E +++Y + +++K PP+ S + N L L + I+SK+
Sbjct: 1435 AASLEKVKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKR 1494
Query: 818 R----------KNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQL 867
V ++ +++ +C +L C S R ++SVTLEQ IL H L
Sbjct: 1495 TAACANTACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGL 1554
Query: 868 HKDFFIRALDCMRREGCRIENVLKNIKCR 896
+ ++A D MR++G R++N KN+ R
Sbjct: 1555 PPRYIMQATDVMRKQGARVQNTAKNLGVR 1583
>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
exchange factor 1 [Homo sapiens]
Length = 1659
Score = 97.8 bits (242), Expect = 4e-20
Identities = 95/355 (26%), Positives = 162/355 (45%), Gaps = 48/355 (13%)
Query: 584 ILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKL 643
I TL D + V K L LL+ L LRRD +F QAL VC F +L
Sbjct: 1289 IKTLVDNIQRYVEDGKNQLLLALLKCTDTELQ------LRRDAIFCQALVAAVCTFSEQL 1342
Query: 644 QTSL---------YDPG-------FLQQLHTVGLIVQYEGLLS--TYSDEIGMLEDMAVG 685
+L Y+ +L+Q+ G+++ + LLS T +E MLED+ V
Sbjct: 1343 LAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVT 1402
Query: 686 ISDLKKVAFKIIEAKSN-----DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLH 740
+S+L V F + N +V I G R+ V L + F LP +++ G L
Sbjct: 1403 LSELDNVTFSFKQLDENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLR 1462
Query: 741 VYPVLFNVGINEQQTLAERFGDVS--LQESINQENFELLQEYYK----IFMEK--MPPDY 792
++ LF + + L + LQ+ IN ++ E +Q+YY+ ++E+ +P D
Sbjct: 1463 LHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKVQQYYRKLRAFYLERSNLPTDA 1522
Query: 793 ----ISHFQEQNDLKALLE--NLLQNIQSKK-----RKNVEIMWLAATICRKLNGIRFTC 841
+ Q + AL E L+++ K ++ +++ +C +L +
Sbjct: 1523 STTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAGSVGAGLIPISSELCYRLGACQMVM 1582
Query: 842 CKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCR 896
C + R+++SV+LEQ +IL H L ++A D MR++G R+E + KN++ +
Sbjct: 1583 CGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNLRVK 1637
Score = 30.4 bits (67), Expect = 7.9
Identities = 26/127 (20%), Positives = 50/127 (39%), Gaps = 10/127 (7%)
Query: 238 LYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELS------P 291
+Y + ++ + E++ E F + +++ D + + L LS P
Sbjct: 856 VYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSSAIVTMP 915
Query: 292 HWD--NLRKNVLTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKT--LEFVPINLHLQ 347
H++ N+ L Q + YQ+ +L FK + + L+F P N H+
Sbjct: 916 HFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHIN 975
Query: 348 RMQVHSP 354
M+V P
Sbjct: 976 LMEVSYP 982
>gi|88703066 copine-like protein [Homo sapiens]
Length = 553
Score = 38.5 bits (88), Expect = 0.029
Identities = 34/152 (22%), Positives = 69/152 (45%), Gaps = 18/152 (11%)
Query: 40 QLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFP 99
++E ++C++L+ K + +V + Q + TE+++ T +P F+ F
Sbjct: 15 KIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVR--KFV 72
Query: 100 SEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSK 159
+Y E+ ++ VY+V K++ + + KD FLG A +GE++ +
Sbjct: 73 LDYFFEEKQNLRFDVYNVDSKTN-------ISKPKD--------FLGQAFLALGEVIGGQ 117
Query: 160 EQLLVLSLRTSDGGKVVGTIEVSVVKMGEIED 191
+ +L T GK GTI ++ ++ D
Sbjct: 118 GSRVERTL-TGVPGKKCGTILLTAEELSNCRD 148
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 36.6 bits (83), Expect = 0.11
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 27/152 (17%)
Query: 769 INQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKA----LLENLLQNIQSKKRKNVEI- 823
I +E L++Y K+ E + + QE NDLKA L LL+ +SKKR +I
Sbjct: 548 IVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIE 607
Query: 824 ---MWLAATICRKLNGIRF-TCCKSAKDRT-SMSVTLEQCSIL---RDEHQL-------- 867
LAA I + ++ K A +RT +SV +E S + +DE++
Sbjct: 608 SYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSET 667
Query: 868 ------HKDFFIRALDCMRREGCRIENVLKNI 893
KD F + D +R++ +E V N+
Sbjct: 668 QIKFNALKDKFRKTRDSLRKKSLALETVQNNL 699
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 34.7 bits (78), Expect = 0.42
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Query: 471 LALYTARPGGILKKPPSPKSSTEESSPQDQPPVMR---GQDSIPHHSDYDEE 519
LAL RPGG +P S+T + P QPP R G D + H++ D E
Sbjct: 405 LALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGE 456
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 34.7 bits (78), Expect = 0.42
Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 27/152 (17%)
Query: 769 INQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKA----LLENLLQNIQSKKRKNVEI- 823
I +E L++Y K+ E + + QE NDLKA L LL+ +SKKR +I
Sbjct: 548 IVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIE 607
Query: 824 ---MWLAATICRKLNGIRF-TCCKSAKDRT-SMSVTLEQCSIL---RDEHQL-------- 867
LAA I + ++ K A +RT +SV +E S + +DE++
Sbjct: 608 SYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSET 667
Query: 868 ------HKDFFIRALDCMRREGCRIENVLKNI 893
KD F + D +R++ +E V ++
Sbjct: 668 QIKFNALKDKFRKTRDSLRKKSLALETVQNDL 699
>gi|22748811 hypothetical protein LOC127795 [Homo sapiens]
Length = 546
Score = 34.7 bits (78), Expect = 0.42
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 21/123 (17%)
Query: 63 VQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSH 122
+Q+ + + Q ++ S E+V + FL S+YP + L K +SH
Sbjct: 229 LQLPTVKILCQRFSKRGSPEMVNYEKLLWFLNSAA--SDYPQQNKAAADLR----KTESH 282
Query: 123 DTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVS 182
T S P+H PEV RS L ++L ++LRT++G + + +S
Sbjct: 283 GTHSQSTPPQHSSSQPEVNRSLL---------------EILKMALRTTNGRLNIDNLNLS 327
Query: 183 VVK 185
K
Sbjct: 328 FRK 330
>gi|28872803 myeloid translocation gene on chromosome 16 isoform
MTG16a [Homo sapiens]
Length = 653
Score = 32.7 bits (73), Expect = 1.6
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 486 PSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDK 541
P P+ E P P R ++ I H E EW W ++ LNCI+ MV+K
Sbjct: 360 PDPRELRERHRPLVVPG-SRQEEVIDHK--LTEREWAEEWKHLNNLLNCIMDMVEK 412
>gi|28872805 myeloid translocation gene on chromosome 16 isoform
MTG16b [Homo sapiens]
Length = 567
Score = 32.7 bits (73), Expect = 1.6
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 486 PSPKSSTEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDK 541
P P+ E P P R ++ I H E EW W ++ LNCI+ MV+K
Sbjct: 274 PDPRELRERHRPLVVPG-SRQEEVIDHK--LTEREWAEEWKHLNNLLNCIMDMVEK 326
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 32.7 bits (73), Expect = 1.6
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 27/152 (17%)
Query: 769 INQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKA----LLENLLQNIQSKKRKNVEI- 823
I +E L++Y K+ E + + QE NDLKA L LL+ +SKKR +I
Sbjct: 548 IVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIE 607
Query: 824 ---MWLAATICRKLNGIRF-TCCKSAKDRT-SMSVTLEQCSILR-------------DEH 865
LAA I + ++ K A +RT +SV +E S + E
Sbjct: 608 SYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSET 667
Query: 866 QLH----KDFFIRALDCMRREGCRIENVLKNI 893
Q+ KD F + D +R++ +E V ++
Sbjct: 668 QIKFNALKDKFRKTRDSLRKKSLALETVQNDL 699
>gi|217416374 hypothetical protein LOC92749 [Homo sapiens]
Length = 740
Score = 32.3 bits (72), Expect = 2.1
Identities = 49/191 (25%), Positives = 79/191 (41%), Gaps = 17/191 (8%)
Query: 654 QQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKI---IEAKSNDVLPVI-T 709
QQLH GL+ L+S E+ +D V DLKK + I +E V V+ T
Sbjct: 160 QQLHCAGLLEDKNKLISELQQELKTKDDQYV--KDLKKQSDDICLLLERMEEQVKNVMKT 217
Query: 710 GRREHYVVEVKLPARMFESLPLQIKE-GQLLHVYPVLFNVGINEQQTLAERFGDVSLQES 768
R E Y +E E L K+ Q L + +N + E + ++
Sbjct: 218 FREELYNIEKAFEVERQELLASNKKKWEQALQAHNAKELEYLNNRMKKVEDY-----EKQ 272
Query: 769 INQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALL----ENLLQNIQSKKRKNVEIM 824
+N++ +EY I + K+ D Q+ KA+ E L N+Q K+++ E
Sbjct: 273 LNRQRIWDCEEYNMIKI-KLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQVLKKRDEEST 331
Query: 825 WLAATICRKLN 835
+ + RK+N
Sbjct: 332 VIKSQQKRKIN 342
>gi|46488923 astrotactin isoform 1 [Homo sapiens]
Length = 1294
Score = 32.0 bits (71), Expect = 2.7
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 82 EIVEGTRDPLFLTGVTFPSE---YPIYEETKIKLTVYDVK 118
EI E T DP FLTG+ SE YP+ + K++ +Y +K
Sbjct: 780 EISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIK 819
>gi|46488921 astrotactin isoform 2 [Homo sapiens]
Length = 1216
Score = 32.0 bits (71), Expect = 2.7
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 82 EIVEGTRDPLFLTGVTFPSE---YPIYEETKIKLTVYDVK 118
EI E T DP FLTG+ SE YP+ + K++ +Y +K
Sbjct: 780 EISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIK 819
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 31.6 bits (70), Expect = 3.6
Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 428 ADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPS 487
A L AS PDS + +LK+ E+ A + + ++ + A A PG PP
Sbjct: 539 ASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPP 598
Query: 488 P---------KSSTEESSPQDQPPVMRGQDSI 510
P +++ ES+PQ+ P M S+
Sbjct: 599 PPPPLGPHSNRTTPPESAPQNGPSPMAALMSV 630
>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
sapiens]
Length = 472
Score = 31.2 bits (69), Expect = 4.7
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 278 CRNQEIKELG--------ELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSFKSS 329
CR ++ KE+G E+ LRKNV H DQ VN +D ++ S+ KS
Sbjct: 182 CRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVN--EDSEGRDLRQVTSTTKSC 239
Query: 330 SSKGEKT------LEFVPINLHLQRM 349
K E T L F+ + + QRM
Sbjct: 240 REKTELTPDQQTLLHFIMDSYNKQRM 265
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 31.2 bits (69), Expect = 4.7
Identities = 19/65 (29%), Positives = 25/65 (38%)
Query: 457 FVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSPQDQPPVMRGQDSIPHHSDY 516
F+H L R GG L P+ K+S+ +S P PP QDS +
Sbjct: 596 FLHGNASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYEN 655
Query: 517 DEEEW 521
E W
Sbjct: 656 SEGGW 660
>gi|68508961 centromere protein C 1 [Homo sapiens]
Length = 943
Score = 31.2 bits (69), Expect = 4.7
Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 21/148 (14%)
Query: 317 ELSKETGSSFKSSSSKGEKTLEFV--PINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQ 374
E K S SS K E +L+FV P + +Q H H K DV + P +
Sbjct: 77 ECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDS--- 133
Query: 375 GFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNS 434
+K+ R + + + Y S + + + ++++Q +++ +S
Sbjct: 134 -------KKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQ---------NVIPSS 177
Query: 435 ASQHSPDSLKNSLKMLSEKTELFVHAFK 462
A + + +NS+ ML TE+ V K
Sbjct: 178 AQKRETYTFENSVNMLPSSTEVSVKTKK 205
>gi|125625357 Sp2 transcription factor [Homo sapiens]
Length = 613
Score = 31.2 bits (69), Expect = 4.7
Identities = 33/141 (23%), Positives = 60/141 (42%), Gaps = 21/141 (14%)
Query: 384 LLHRFETERRNTGYQFIYYSPENTAKAKEVLSNI-NQLQPLIATHADLLLNSASQHSPDS 442
++++ N YQ + + ++ +V N+ NQ+Q + T+ ++ S S H P
Sbjct: 119 MINKGTRSNANIQYQAVPQIQASNSQTIQVQPNLTNQIQIIPGTNQAIITPSPSSHKPVP 178
Query: 443 LKNSLKMLSEKTELFVHAFKDQL--------------VRSALLALYTARPGGIL-KKPPS 487
+K + S T V + + + V + + A T P +L + PP+
Sbjct: 179 IKPAPIQKSSTTTTPVQSGANVVKLTGGGGNVTLTLPVNNLVNASDTGAPTQLLTESPPT 238
Query: 488 PKSST-----EESSPQDQPPV 503
P S T ++S P QPPV
Sbjct: 239 PLSKTNKKARKKSLPASQPPV 259
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 31.2 bits (69), Expect = 4.7
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 27/151 (17%)
Query: 764 SLQESINQENFELLQEY---YKIFMEKMP--------------PDYISHFQEQNDLK--- 803
S Q+ + Q +L +EY K+ EK D+ S + + DLK
Sbjct: 1603 SCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTK 1662
Query: 804 ALLEN---LLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSI 860
ALL + +L ++++ EI A + +L FTC + K R +M V +E +
Sbjct: 1663 ALLADAQLMLDHLKNSAPSKREI----AQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1718
Query: 861 LRDEHQLHKDFFIRALDCMRREGCRIENVLK 891
D+ K L ++RE I+N L+
Sbjct: 1719 QIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 31.2 bits (69), Expect = 4.7
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 27/151 (17%)
Query: 764 SLQESINQENFELLQEY---YKIFMEKMP--------------PDYISHFQEQNDLK--- 803
S Q+ + Q +L +EY K+ EK D+ S + + DLK
Sbjct: 1603 SCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTK 1662
Query: 804 ALLEN---LLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSI 860
ALL + +L ++++ EI A + +L FTC + K R +M V +E +
Sbjct: 1663 ALLADAQLMLDHLKNSAPSKREI----AQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1718
Query: 861 LRDEHQLHKDFFIRALDCMRREGCRIENVLK 891
D+ K L ++RE I+N L+
Sbjct: 1719 QIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749
>gi|42558250 membrane component chromosome 11 surface marker 1
isoform 1 [Homo sapiens]
Length = 709
Score = 31.2 bits (69), Expect = 4.7
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 279 RNQEIKELGELSPHWDNLRKNVLTHCDQM--VNMYQDILT--ELSKETGSSFKSSSSKGE 334
RN E K+ G+L + + + K + DQ+ V+ YQ++ E +KE SF + S +
Sbjct: 66 RNLE-KKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQ 124
Query: 335 KTLEFVPINLHLQRMQVHSPHLKDAL 360
KT++ L R + LK L
Sbjct: 125 KTIKKTARREQLMREEAEQKRLKTVL 150
>gi|42734503 membrane component chromosome 11 surface marker 1
isoform 2 [Homo sapiens]
Length = 694
Score = 31.2 bits (69), Expect = 4.7
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 279 RNQEIKELGELSPHWDNLRKNVLTHCDQM--VNMYQDILT--ELSKETGSSFKSSSSKGE 334
RN E K+ G+L + + + K + DQ+ V+ YQ++ E +KE SF + S +
Sbjct: 66 RNLE-KKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQ 124
Query: 335 KTLEFVPINLHLQRMQVHSPHLKDAL 360
KT++ L R + LK L
Sbjct: 125 KTIKKTARREQLMREEAEQKRLKTVL 150
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
[Homo sapiens]
Length = 759
Score = 30.8 bits (68), Expect = 6.1
Identities = 17/58 (29%), Positives = 34/58 (58%), Gaps = 3/58 (5%)
Query: 621 TLRRDIVFSQALAGLVCGFIIKLQTSLYDPG-FLQQLHTVG--LIVQYEGLLSTYSDE 675
TL++ +F+ AGL+ ++KLQ +Y PG ++ + +G + + EG L+ +D+
Sbjct: 542 TLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADD 599
>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
sapiens]
Length = 690
Score = 30.8 bits (68), Expect = 6.1
Identities = 17/58 (29%), Positives = 34/58 (58%), Gaps = 3/58 (5%)
Query: 621 TLRRDIVFSQALAGLVCGFIIKLQTSLYDPG-FLQQLHTVG--LIVQYEGLLSTYSDE 675
TL++ +F+ AGL+ ++KLQ +Y PG ++ + +G + + EG L+ +D+
Sbjct: 473 TLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADD 530
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,483,702
Number of Sequences: 37866
Number of extensions: 1603960
Number of successful extensions: 5441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 5387
Number of HSP's gapped (non-prelim): 62
length of query: 924
length of database: 18,247,518
effective HSP length: 112
effective length of query: 812
effective length of database: 14,006,526
effective search space: 11373299112
effective search space used: 11373299112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.