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Search of human proteins with 155969705
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155969705 chloride channel Kb [Homo sapiens]
(687 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155969705 chloride channel Kb [Homo sapiens] 1382 0.0
gi|112382220 chloride channel Ka isoform 1 [Homo sapiens] 1266 0.0
gi|112382222 chloride channel Ka isoform 2 [Homo sapiens] 1260 0.0
gi|156104869 chloride channel 2 [Homo sapiens] 530 e-150
gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens] 481 e-136
gi|153252026 chloride channel 4 [Homo sapiens] 186 8e-47
gi|189217923 chloride channel 5 isoform a [Homo sapiens] 186 8e-47
gi|189217921 chloride channel 5 isoform a [Homo sapiens] 186 8e-47
gi|4557473 chloride channel 5 isoform b [Homo sapiens] 186 8e-47
gi|55770838 chloride channel 3 isoform b [Homo sapiens] 178 1e-44
gi|55770840 chloride channel 3 isoform e [Homo sapiens] 174 2e-43
gi|167466160 chloride channel 7 isoform b [Homo sapiens] 167 4e-41
gi|14149607 chloride channel 7 isoform a [Homo sapiens] 167 4e-41
gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens] 122 1e-27
gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens] 73 8e-13
gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens] 48 3e-05
gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens] 48 3e-05
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 31 4.4
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 31 4.4
gi|5032213 solute carrier family 35, member B1 [Homo sapiens] 31 4.4
gi|45827690 BTB and CNC homology 1 transcription factor isoform ... 30 5.7
gi|4502353 BTB and CNC homology 1 transcription factor isoform a... 30 5.7
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ... 30 7.4
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 30 9.7
gi|19526475 outer dense fiber of sperm tails 3 [Homo sapiens] 30 9.7
gi|24415404 MDN1, midasin homolog [Homo sapiens] 30 9.7
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 30 9.7
gi|38146109 arginine/serine-rich coiled-coil 2 isoform c [Homo s... 30 9.7
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 30 9.7
gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens] 30 9.7
>gi|155969705 chloride channel Kb [Homo sapiens]
Length = 687
Score = 1382 bits (3576), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM 60
MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM
Sbjct: 1 MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM 60
Query: 61 ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG
Sbjct: 61 ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
Query: 121 SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL 180
SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL
Sbjct: 121 SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL 180
Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF 240
GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF
Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF 240
Query: 241 FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL 300
FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL
Sbjct: 241 FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL 300
Query: 301 FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS 360
FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS
Sbjct: 301 FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS 360
Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP
Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
Query: 421 MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH 480
MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH
Sbjct: 421 MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH 480
Query: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI 540
TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI
Sbjct: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI 540
Query: 541 GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV 600
GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV
Sbjct: 541 GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV 600
Query: 601 QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS 660
QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS
Sbjct: 601 QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS 660
Query: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
RGRAVGCVSWVEMKKAISNLTNPPAPK
Sbjct: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
>gi|112382220 chloride channel Ka isoform 1 [Homo sapiens]
Length = 687
Score = 1266 bits (3277), Expect = 0.0
Identities = 627/687 (91%), Positives = 652/687 (94%)
Query: 1 MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM 60
MEE VGLREG SG+PVTLQELWGPCP IRR I+GGLEWLKQK+FRLGEDWYFLMTLGVLM
Sbjct: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
Query: 61 ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
ALVS AM+ A+ VVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG
Sbjct: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
Query: 121 SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL 180
SGIPE+KTMLAGV+LEDYLDIKNFGAKVVGLSCTLA GSTLFLGKVGPFVHLSVM+AAYL
Sbjct: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF 240
GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSV DYWRGF
Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
Query: 241 FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL 300
FAATCGAF+FRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGG+CG+L AYL
Sbjct: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
Query: 301 FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS 360
FCQR F FI+ NR+SSKLLATSKPVYSALATL+LASITYPP G FLASRLSMKQHLDS
Sbjct: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP
Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
Query: 421 MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH 480
MPAGYFMPIF+ GAAIGRL GE L+ FPEGIV GG+TNPIMPGGYALAGAAAFSGAVTH
Sbjct: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
Query: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI 540
TISTALLAFE+TGQIVHALPVLMAVLAANAIAQSCQPSFYDGT+IVKKLPYLPRILGRNI
Sbjct: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
Query: 541 GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV 600
GSH VRVEHFMNHSITTLAKD PLEEVVKVVTSTDV +YPLVESTESQILVGIV+RAQLV
Sbjct: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
Query: 601 QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS 660
QAL+AEPPS APGHQQCLQDILA GCPTEPVTL L ET+LH+A NLF+LLNL SLFVTS
Sbjct: 601 QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 660
Query: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
RGRAVGCVSWVEMKKAISNLTNPPAPK
Sbjct: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
>gi|112382222 chloride channel Ka isoform 2 [Homo sapiens]
Length = 686
Score = 1260 bits (3260), Expect = 0.0
Identities = 626/687 (91%), Positives = 651/687 (94%), Gaps = 1/687 (0%)
Query: 1 MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM 60
MEE VGLREG SG+PVTLQELWGPCP IRR I+GGLEWLKQK+FRLGEDWYFLMTLGVLM
Sbjct: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
Query: 61 ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
ALVS AM+ A+ VVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG
Sbjct: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
Query: 121 SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL 180
SGIPE+KTMLAGV+LEDYLDIKNFGAKVVGLSCTLA GSTLFLGKVGPFVHLSVM+AAYL
Sbjct: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF 240
GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSV DYWRGF
Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
Query: 241 FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL 300
FAATCGAF+FRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGG+CG+L AYL
Sbjct: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
Query: 301 FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS 360
FCQR F FI+ NR+SSKLLATSKPVYSALATL+LASITYPP G FLASRLSMKQHLDS
Sbjct: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP
Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
Query: 421 MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH 480
MPAGYFMPIF+ GAAIGRL GE L+ FPEGIV GG+TNPIMPGGYALAGAAAFSGAVTH
Sbjct: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
Query: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI 540
TISTALLAFE+TGQIVHALPVLMAVLAANAIAQSCQPSFYDGT+IVKKLPYLPRILGRNI
Sbjct: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
Query: 541 GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV 600
GSH VRVEHFMNHSITTLAKD PLEEVVKVVTSTDV +YPLVESTESQILVGIV+RAQLV
Sbjct: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
Query: 601 QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS 660
QAL+AEPPS APGH QCLQDILA GCPTEPVTL L ET+LH+A NLF+LLNL SLFVTS
Sbjct: 601 QALQAEPPSRAPGH-QCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 659
Query: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
RGRAVGCVSWVEMKKAISNLTNPPAPK
Sbjct: 660 RGRAVGCVSWVEMKKAISNLTNPPAPK 686
>gi|156104869 chloride channel 2 [Homo sapiens]
Length = 898
Score = 530 bits (1365), Expect = e-150
Identities = 289/619 (46%), Positives = 398/619 (64%), Gaps = 16/619 (2%)
Query: 45 RLGEDWYFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALV 104
R+GEDW FL+ LG+LMALVS MD A+ + ++A QW+ R + S LL+YL+W YPV L+
Sbjct: 86 RVGEDWIFLVLLGLLMALVSWVMDYAIAACLQAQQWMSRGLNTSILLQYLAWVTYPVVLI 145
Query: 105 SFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLG 164
+FS+GF+Q + P + GSGIPE+KT+L GVVL++YL +K F AKV+GL+C L GS + LG
Sbjct: 146 TFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFIAKVIGLTCAL--GSGMPLG 203
Query: 165 KVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSI 224
K GPFVH++ M AA L + + G EN+S+ EML AA AVGV FAAP GVLFSI
Sbjct: 204 KEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSI 263
Query: 225 EVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFF 284
EV S+ F+V +YWRGFFAAT AF+FR+LAV+N ++ETIT+L+KT FR+D PFDL E+
Sbjct: 264 EVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPA 323
Query: 285 FVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSA 344
F +G G G+ +++ R +R + ++ L + ++ AL TL+++++T+PP
Sbjct: 324 FAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGF 383
Query: 345 GRFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAF 404
G+F+A +LS K+ L +LFDN +W EEL+P W PR +F TL
Sbjct: 384 GQFMAGQLSQKETLVTLFDNRTWVRQGL------VEELEPPSTSQAWNPPRANVFLTLVI 437
Query: 405 FLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPG 464
F++MKFWM LATTIP+P G FMP+FV GAA GRL GE+++ FP+GI T I+PG
Sbjct: 438 FILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPG 497
Query: 465 GYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTV 524
GYA+ GAAA +GAVTHT+STA++ FE+TGQI H LPV++AV+ ANA+AQS QPS YD +
Sbjct: 498 GYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSII 557
Query: 525 IVKKLPYLPRILGRNIGSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVES 584
+KKLPYLP + +RVRVE M + +A ++ + T LVES
Sbjct: 558 RIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVES 617
Query: 585 TESQILVGIVRRAQLVQALKAE-PPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHE 643
ES IL+G + R+Q+V L A+ P+ H Q T P++ + P T E
Sbjct: 618 PESMILLGSIERSQVVALLGAQLSPARRRQHMQ-----ERRATQTSPLSDQEGPPTP--E 670
Query: 644 AHNLFELLNLHSLFVTSRG 662
A F++ S F +RG
Sbjct: 671 ASVCFQVNTEDSAFPAARG 689
Score = 50.4 bits (119), Expect = 5e-06
Identities = 24/63 (38%), Positives = 37/63 (58%)
Query: 615 QQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMK 674
QQ + + + C +P +L TSLH+ H +F LL + +VTS GR +G V+ E++
Sbjct: 777 QQLDEPVNFSDCKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELR 836
Query: 675 KAI 677
KAI
Sbjct: 837 KAI 839
>gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens]
Length = 988
Score = 481 bits (1239), Expect = e-136
Identities = 251/559 (44%), Positives = 365/559 (65%), Gaps = 11/559 (1%)
Query: 45 RLGEDWYFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALV 104
+LGEDW FL+ LG+LMALVS +MD ++A++W Y ++ S L++L W +P+ L+
Sbjct: 113 KLGEDWIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLI 172
Query: 105 SFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLG 164
FS+ F I+P + GSGIPE+KT+L GVVL++YL +K F AKVV L+ L GS + +G
Sbjct: 173 LFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGL--GSGIPVG 230
Query: 165 KVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSI 224
K GPFVH++ + AA L + + G E +++L AVGV F P GVLFSI
Sbjct: 231 KEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSI 290
Query: 225 EVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFF 284
EV S++F+V +YWRGFFAAT AF+FR+LAV+N + TIT+L++T+FR+D PFDL E+
Sbjct: 291 EVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPA 350
Query: 285 FVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSA 344
F A+G CG+LG+ +++ R +R ++ S+ LA + +Y + T V+AS T+PP
Sbjct: 351 FAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGM 410
Query: 345 GRFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAF 404
G+F+A L ++ + +LFDN++W + PE L +W HPR + +
Sbjct: 411 GQFMAGELMPREAISTLFDNNTWVKHAGD-----PESLGQSAVW---IHPRVNVVIIIFL 462
Query: 405 FLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPG 464
F VMKFWM I+ATT+P+P G FMP+FV GAA GRL GE ++ +FP+GI+ I I+PG
Sbjct: 463 FFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPG 522
Query: 465 GYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTV 524
GYA+ GAAA +GAV+HT+STA++ FE+TGQI H LP+++AV+ AN +AQS QPS YD +
Sbjct: 523 GYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSII 582
Query: 525 IVKKLPYLPRILGRNIGSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVES 584
VKKLPYLP + + + + VE M + ++ E+ ++ +T V PLV+S
Sbjct: 583 QVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDS 642
Query: 585 TESQILVGIVRRAQLVQAL 603
+S IL+G V R++L QAL
Sbjct: 643 KDSMILLGSVERSEL-QAL 660
Score = 47.8 bits (112), Expect = 3e-05
Identities = 24/67 (35%), Positives = 37/67 (55%)
Query: 615 QQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMK 674
+Q Q + C + +L +T+LH+ H LF LL LH +VTS G+ G ++ E++
Sbjct: 808 EQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQ 867
Query: 675 KAISNLT 681
KAI T
Sbjct: 868 KAIEGHT 874
>gi|153252026 chloride channel 4 [Homo sapiens]
Length = 760
Score = 186 bits (471), Expect = 8e-47
Identities = 171/647 (26%), Positives = 287/647 (44%), Gaps = 87/647 (13%)
Query: 84 EIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKN 143
E +++L YL + ++ + + + P + GSGIPE+KT+L+G ++ YL
Sbjct: 144 EGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWT 203
Query: 144 FGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVA 203
K V L L S L LGK GP VH++ + + + +N+ K+ E+L A
Sbjct: 204 LLIKTVTL--VLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKY---SKNEGKRREVLSA 258
Query: 204 AAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETI 263
AAA GV+ F AP GVLFS+E +S +F + WR FFAA AF R + F + +
Sbjct: 259 AAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR--- 315
Query: 264 TSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATS 323
L P+ + E+F F+ LG G+ G+ ++ C N + + T
Sbjct: 316 --LVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRC---------NIAWCRRRKTTR 364
Query: 324 KPVYSALATLVLASIT----YPPSAGRFLASRLSMKQHLD-------SLFDNHSWALMTQ 372
Y L +V+ +IT YP R S L + D L D + MT+
Sbjct: 365 LGKYPVLEVIVVTAITAIIAYPNPYTRQSTSELISELFNDCGALESSQLCDYINDPNMTR 424
Query: 373 --NSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIF 430
+ P P + W+ LA L+ K + I + +P+G F+P
Sbjct: 425 PVDDIPDRPAGVGVYTAMWQ-----------LALALIFKIVVTIFTFGMKIPSGLFIPSM 473
Query: 431 VYGAAIGRLFG---ETLSFIFPEGIVAGGITNP----IMPGGYALAGAAAFSGAVTH-TI 482
GA GR+ G E L++ + I+ P + PG YA+ GAAA G VT T+
Sbjct: 474 AVGAIAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTV 533
Query: 483 STALLAFEVTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTVIVKKLPYLPRILGRNIG 541
S ++ FE+TG + + +P++ A + + +A + + Y+ + + P+L ++
Sbjct: 534 SLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLD---VKDEF 590
Query: 542 SHRVRVEHFM-----NHSITTLAKD-MPLEEVVKVVTSTDVAKYPLVESTESQILVGIVR 595
+HR M ++ L +D M +E+V ++ TD +P+V S +S+ L+G +
Sbjct: 591 THRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQ 650
Query: 596 RAQLVQALK------------------AEPPSWAPG--HQQCLQDILAAGCPTEPVTLKL 635
R +L+ A+K EPP H L+ IL P T +
Sbjct: 651 RRELILAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRIL----NLSPFT--V 704
Query: 636 SPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
+ T + ++F L L VT GR +G ++ ++ + ++ + N
Sbjct: 705 TDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMAN 751
>gi|189217923 chloride channel 5 isoform a [Homo sapiens]
Length = 816
Score = 186 bits (471), Expect = 8e-47
Identities = 175/638 (27%), Positives = 282/638 (44%), Gaps = 78/638 (12%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAK 147
++++ Y + ++ + + + P + GSGIPE+KT+L+G ++ YL K
Sbjct: 205 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 264
Query: 148 VVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206
+ L LA S L LGK GP VH+ A G + + +N++K+ E+L AAAA
Sbjct: 265 TITL--VLAVSSGLSLGKEGPLVHV----ACCCGNILCHCFNKYRKNEAKRREVLSAAAA 318
Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSL 266
GV+ F AP GVLFS+E +S +F + WR FFAA AF R + F + + L
Sbjct: 319 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 375
Query: 267 YKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNN-RFSSKLLATSKP 325
+ F P+ L E+ F+ LG G+ G+ FIR N + K T
Sbjct: 376 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL----------FIRTNIAWCRKRKTTQLG 423
Query: 326 VYSALATLVLASIT----YPPSAGRFLASRLSMKQHLD-SLFDN-------HSWALMTQN 373
Y + LV+ +IT +P R S L + D L D+ + +
Sbjct: 424 KYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGG 483
Query: 374 SSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYG 433
P P + W+ LA L++K + I + +P+G F+P G
Sbjct: 484 ELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGLFIPSMAVG 532
Query: 434 AAIGRLFG---ETLSFIFPEGIVAGGITNP----IMPGGYALAGAAAFSGAVTH-TISTA 485
A GRL G E L++ E V + I PG YA+ GAAA G VT T+S
Sbjct: 533 AIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLV 592
Query: 486 LLAFEVTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTVIVKKLPYLPRILGRNIGSHR 544
++ FE+TG + + +P++ A + + +A + + YD + + P+L + +H+
Sbjct: 593 VIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE---AKEEFAHK 649
Query: 545 VRVEHFM-----NHSITTLAKD-MPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQ 598
M + +T L +D M +E+V +++ T + +P+V S ESQ LVG V R
Sbjct: 650 TLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRD 709
Query: 599 LVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVT---------LKLSP-----ETSLHEA 644
L+ +++ + P P T L LSP T +
Sbjct: 710 LIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVTDLTPMEIV 769
Query: 645 HNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
++F L L VT GR +G ++ ++ K I+ + N
Sbjct: 770 VDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 807
>gi|189217921 chloride channel 5 isoform a [Homo sapiens]
Length = 816
Score = 186 bits (471), Expect = 8e-47
Identities = 175/638 (27%), Positives = 282/638 (44%), Gaps = 78/638 (12%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAK 147
++++ Y + ++ + + + P + GSGIPE+KT+L+G ++ YL K
Sbjct: 205 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 264
Query: 148 VVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206
+ L LA S L LGK GP VH+ A G + + +N++K+ E+L AAAA
Sbjct: 265 TITL--VLAVSSGLSLGKEGPLVHV----ACCCGNILCHCFNKYRKNEAKRREVLSAAAA 318
Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSL 266
GV+ F AP GVLFS+E +S +F + WR FFAA AF R + F + + L
Sbjct: 319 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 375
Query: 267 YKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNN-RFSSKLLATSKP 325
+ F P+ L E+ F+ LG G+ G+ FIR N + K T
Sbjct: 376 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL----------FIRTNIAWCRKRKTTQLG 423
Query: 326 VYSALATLVLASIT----YPPSAGRFLASRLSMKQHLD-SLFDN-------HSWALMTQN 373
Y + LV+ +IT +P R S L + D L D+ + +
Sbjct: 424 KYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGG 483
Query: 374 SSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYG 433
P P + W+ LA L++K + I + +P+G F+P G
Sbjct: 484 ELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGLFIPSMAVG 532
Query: 434 AAIGRLFG---ETLSFIFPEGIVAGGITNP----IMPGGYALAGAAAFSGAVTH-TISTA 485
A GRL G E L++ E V + I PG YA+ GAAA G VT T+S
Sbjct: 533 AIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLV 592
Query: 486 LLAFEVTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTVIVKKLPYLPRILGRNIGSHR 544
++ FE+TG + + +P++ A + + +A + + YD + + P+L + +H+
Sbjct: 593 VIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE---AKEEFAHK 649
Query: 545 VRVEHFM-----NHSITTLAKD-MPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQ 598
M + +T L +D M +E+V +++ T + +P+V S ESQ LVG V R
Sbjct: 650 TLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRD 709
Query: 599 LVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVT---------LKLSP-----ETSLHEA 644
L+ +++ + P P T L LSP T +
Sbjct: 710 LIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVTDLTPMEIV 769
Query: 645 HNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
++F L L VT GR +G ++ ++ K I+ + N
Sbjct: 770 VDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 807
>gi|4557473 chloride channel 5 isoform b [Homo sapiens]
Length = 746
Score = 186 bits (471), Expect = 8e-47
Identities = 175/638 (27%), Positives = 282/638 (44%), Gaps = 78/638 (12%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAK 147
++++ Y + ++ + + + P + GSGIPE+KT+L+G ++ YL K
Sbjct: 135 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 194
Query: 148 VVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206
+ L LA S L LGK GP VH+ A G + + +N++K+ E+L AAAA
Sbjct: 195 TITL--VLAVSSGLSLGKEGPLVHV----ACCCGNILCHCFNKYRKNEAKRREVLSAAAA 248
Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSL 266
GV+ F AP GVLFS+E +S +F + WR FFAA AF R + F + + L
Sbjct: 249 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 305
Query: 267 YKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNN-RFSSKLLATSKP 325
+ F P+ L E+ F+ LG G+ G+ FIR N + K T
Sbjct: 306 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL----------FIRTNIAWCRKRKTTQLG 353
Query: 326 VYSALATLVLASIT----YPPSAGRFLASRLSMKQHLD-SLFDN-------HSWALMTQN 373
Y + LV+ +IT +P R S L + D L D+ + +
Sbjct: 354 KYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGG 413
Query: 374 SSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYG 433
P P + W+ LA L++K + I + +P+G F+P G
Sbjct: 414 ELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGLFIPSMAVG 462
Query: 434 AAIGRLFG---ETLSFIFPEGIVAGGITNP----IMPGGYALAGAAAFSGAVTH-TISTA 485
A GRL G E L++ E V + I PG YA+ GAAA G VT T+S
Sbjct: 463 AIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLV 522
Query: 486 LLAFEVTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTVIVKKLPYLPRILGRNIGSHR 544
++ FE+TG + + +P++ A + + +A + + YD + + P+L + +H+
Sbjct: 523 VIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE---AKEEFAHK 579
Query: 545 VRVEHFM-----NHSITTLAKD-MPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQ 598
M + +T L +D M +E+V +++ T + +P+V S ESQ LVG V R
Sbjct: 580 TLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRD 639
Query: 599 LVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVT---------LKLSP-----ETSLHEA 644
L+ +++ + P P T L LSP T +
Sbjct: 640 LIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVTDLTPMEIV 699
Query: 645 HNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
++F L L VT GR +G ++ ++ K I+ + N
Sbjct: 700 VDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 737
>gi|55770838 chloride channel 3 isoform b [Homo sapiens]
Length = 818
Score = 178 bits (452), Expect = 1e-44
Identities = 168/643 (26%), Positives = 280/643 (43%), Gaps = 87/643 (13%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAK 147
S+++ Y+ + + ++ + + P + GSGIPE+KT+L+G ++ YL K
Sbjct: 206 SYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIK 265
Query: 148 VVGLSCTLACGSTLFLGKVGPFVHLSVMMA---AYLGRVRTTTIGEPENKSKQNEMLVAA 204
+ L LA S L LGK GP VH++ +YL +T N++K+ E+L AA
Sbjct: 266 TITL--VLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYST------NEAKKREVLSAA 317
Query: 205 AAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETIT 264
+A GV+ F AP GVLFS+E +S +F + WR FFAA AF+ R + F + +
Sbjct: 318 SAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSR---- 373
Query: 265 SLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNN-RFSSKLLATS 323
L P+ L E+F F+ LG G+ G+ FIR N + + +T
Sbjct: 374 -LVLFYVEYHTPWYLFELFPFILLGVFGGLWGAF----------FIRANIAWCRRRKSTK 422
Query: 324 KPVYSALATLVLASIT----YPPSAGRFLASRLSMKQHLD-------SLFD--NHSWALM 370
Y L +++A+IT +P R S L + D SL D N A
Sbjct: 423 FGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASK 482
Query: 371 TQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIF 430
+ P P + W+ L L+ K M + I +P+G F+P
Sbjct: 483 IVDDIPDRPAGIGVYSAIWQ-----------LCLALIFKIIMTVFTFGIKVPSGLFIPSM 531
Query: 431 VYGAAIGRLFGETLS---------FIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH- 480
GA GR+ G + FIF E G + I PG YA+ GAAA G VT
Sbjct: 532 AIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVG--ADCITPGLYAMVGAAACLGGVTRM 589
Query: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTVIVKKLPYLPRILGRN 539
T+S ++ FE+TG + + +P++ AV+ + + + + Y+ + + P+L +
Sbjct: 590 TVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLD---AKE 646
Query: 540 IGSHRVRVEHFM-----NHSITTLAKD-MPLEEVVKVVTSTDVAKYPLVESTESQILVGI 593
+H M + + L +D M ++++ ++ T +P++ S ESQ LVG
Sbjct: 647 EFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGF 706
Query: 594 VRRAQL---VQALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKL-----------SPET 639
R L +++ + + + C + P LKL + T
Sbjct: 707 ALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHT 766
Query: 640 SLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
+ ++F L L VT GR +G ++ ++ + ++ N
Sbjct: 767 PMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTAN 809
>gi|55770840 chloride channel 3 isoform e [Homo sapiens]
Length = 866
Score = 174 bits (442), Expect = 2e-43
Identities = 166/630 (26%), Positives = 273/630 (43%), Gaps = 87/630 (13%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAK 147
S+++ Y+ + + ++ + + P + GSGIPE+KT+L+G ++ YL K
Sbjct: 206 SYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIK 265
Query: 148 VVGLSCTLACGSTLFLGKVGPFVHLSVMMA---AYLGRVRTTTIGEPENKSKQNEMLVAA 204
+ L LA S L LGK GP VH++ +YL +T N++K+ E+L AA
Sbjct: 266 TITL--VLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYST------NEAKKREVLSAA 317
Query: 205 AAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETIT 264
+A GV+ F AP GVLFS+E +S +F + WR FFAA AF+ R + F + +
Sbjct: 318 SAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSR---- 373
Query: 265 SLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNN-RFSSKLLATS 323
L P+ L E+F F+ LG G+ G+ FIR N + + +T
Sbjct: 374 -LVLFYVEYHTPWYLFELFPFILLGVFGGLWGAF----------FIRANIAWCRRRKSTK 422
Query: 324 KPVYSALATLVLASIT----YPPSAGRFLASRLSMKQHLD-------SLFD--NHSWALM 370
Y L +++A+IT +P R S L + D SL D N A
Sbjct: 423 FGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASK 482
Query: 371 TQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIF 430
+ P P + W+ L L+ K M + I +P+G F+P
Sbjct: 483 IVDDIPDRPAGIGVYSAIWQ-----------LCLALIFKIIMTVFTFGIKVPSGLFIPSM 531
Query: 431 VYGAAIGRLFGETLS---------FIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH- 480
GA GR+ G + FIF E G + I PG YA+ GAAA G VT
Sbjct: 532 AIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVG--ADCITPGLYAMVGAAACLGGVTRM 589
Query: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTVIVKKLPYLPRILGRN 539
T+S ++ FE+TG + + +P++ AV+ + + + + Y+ + + P+L +
Sbjct: 590 TVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLD---AKE 646
Query: 540 IGSHRVRVEHFM-----NHSITTLAKD-MPLEEVVKVVTSTDVAKYPLVESTESQILVGI 593
+H M + + L +D M ++++ ++ T +P++ S ESQ LVG
Sbjct: 647 EFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGF 706
Query: 594 VRRAQL---VQALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKL-----------SPET 639
R L +++ + + + C + P LKL + T
Sbjct: 707 ALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHT 766
Query: 640 SLHEAHNLFELLNLHSLFVTSRGRAVGCVS 669
+ ++F L L VT G +G ++
Sbjct: 767 PMEIVVDIFRKLGLRQCLVTHNGIVLGIIT 796
>gi|167466160 chloride channel 7 isoform b [Homo sapiens]
Length = 781
Score = 167 bits (422), Expect = 4e-41
Identities = 172/690 (24%), Positives = 299/690 (43%), Gaps = 103/690 (14%)
Query: 50 WYFLMTLGVLMALVSCAMDLAVES-------VVRAHQWLYREIGDSHLLRYLSWTVYPVA 102
W +G+L LV+C +D+ VE+ V++ + + E G L W A
Sbjct: 103 WVICALIGILTGLVACFIDIVVENLAGLKYRVIKGNIDKFTEKGGLSF-SLLLWATLNAA 161
Query: 103 LVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLF 162
V S I P + GSGIP++K L GV + + +K KV G+ ++ G L
Sbjct: 162 FVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGG--LA 219
Query: 163 LGKVGPFVHLSVMMAAYLGRVRTTTIGEP-------ENKSKQNEMLVAAAAVGVATVFAA 215
+GK GP +H ++AA + + R+T++ +++ + + A AA GV+ F A
Sbjct: 220 VGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGA 279
Query: 216 PFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFR-LLAVFNSEQETITSLYKTSF-RV 273
P GVLFS+E +S ++ + WR FFA+ F +L++++ ++S +F R
Sbjct: 280 PVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRF 339
Query: 274 D---VPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSAL 330
D + + + EI F+A+G + G+LG+ + + R L + V A
Sbjct: 340 DSEKMAYTIHEIPVFIAMGVVGGVLGAVF-NALNYWLTMFRIRYIHRPCLQVIEAVLVAA 398
Query: 331 AT------LVLASITYPPSAGRFLASRLSM-------KQHLDSLFDNHSWALMTQNSSPP 377
T L+ +S P G ++ L + + F+ ++++ PP
Sbjct: 399 VTATVAFVLIYSSRDCQPLQGGSMSYPLQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPP 458
Query: 378 WPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIG 437
Y+P TL F ++ F++ + + AG F+P + GAA G
Sbjct: 459 GS------------YNPL-----TLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWG 501
Query: 438 RLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAA-FSGAVTHTISTALLAFEVTGQIV 496
RLFG +LS++ I A PG YAL GAAA G V T+S ++ E T +
Sbjct: 502 RLFGISLSYLTGAAIWAD-------PGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVT 554
Query: 497 HALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHFMNHSIT 556
+ P+++ ++ A + YD + ++ +P+L + SH + M+ +T
Sbjct: 555 YGFPIMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLH--WEAPVTSHSLTAREVMSTPVT 612
Query: 557 TLAKDMPLEEVVKVV--TSTDVAKYPLVE---STESQILVGIVRRAQLVQALKAEP---- 607
L + + +V V+ T+++ +P+VE T+ L G++ R+QL+ LK +
Sbjct: 613 CLRRREKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLKHKVFVER 672
Query: 608 -------------------PSWAP--------GHQQCLQDILAAGCPTEPVTLKLSPETS 640
P + P ++C D+ P+ P T + E S
Sbjct: 673 SNLGLVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEFMNPS-PYT--VPQEAS 729
Query: 641 LHEAHNLFELLNL-HSLFVTSRGRAVGCVS 669
L LF L L H + V +R + VG V+
Sbjct: 730 LPRVFKLFRALGLRHLVVVDNRNQVVGLVT 759
>gi|14149607 chloride channel 7 isoform a [Homo sapiens]
Length = 805
Score = 167 bits (422), Expect = 4e-41
Identities = 172/690 (24%), Positives = 299/690 (43%), Gaps = 103/690 (14%)
Query: 50 WYFLMTLGVLMALVSCAMDLAVES-------VVRAHQWLYREIGDSHLLRYLSWTVYPVA 102
W +G+L LV+C +D+ VE+ V++ + + E G L W A
Sbjct: 127 WVICALIGILTGLVACFIDIVVENLAGLKYRVIKGNIDKFTEKGGLSF-SLLLWATLNAA 185
Query: 103 LVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLF 162
V S I P + GSGIP++K L GV + + +K KV G+ ++ G L
Sbjct: 186 FVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGG--LA 243
Query: 163 LGKVGPFVHLSVMMAAYLGRVRTTTIGEP-------ENKSKQNEMLVAAAAVGVATVFAA 215
+GK GP +H ++AA + + R+T++ +++ + + A AA GV+ F A
Sbjct: 244 VGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGA 303
Query: 216 PFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFR-LLAVFNSEQETITSLYKTSF-RV 273
P GVLFS+E +S ++ + WR FFA+ F +L++++ ++S +F R
Sbjct: 304 PVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRF 363
Query: 274 D---VPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSAL 330
D + + + EI F+A+G + G+LG+ + + R L + V A
Sbjct: 364 DSEKMAYTIHEIPVFIAMGVVGGVLGAVF-NALNYWLTMFRIRYIHRPCLQVIEAVLVAA 422
Query: 331 AT------LVLASITYPPSAGRFLASRLSM-------KQHLDSLFDNHSWALMTQNSSPP 377
T L+ +S P G ++ L + + F+ ++++ PP
Sbjct: 423 VTATVAFVLIYSSRDCQPLQGGSMSYPLQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPP 482
Query: 378 WPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIG 437
Y+P TL F ++ F++ + + AG F+P + GAA G
Sbjct: 483 GS------------YNPL-----TLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWG 525
Query: 438 RLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAA-FSGAVTHTISTALLAFEVTGQIV 496
RLFG +LS++ I A PG YAL GAAA G V T+S ++ E T +
Sbjct: 526 RLFGISLSYLTGAAIWAD-------PGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVT 578
Query: 497 HALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHFMNHSIT 556
+ P+++ ++ A + YD + ++ +P+L + SH + M+ +T
Sbjct: 579 YGFPIMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLH--WEAPVTSHSLTAREVMSTPVT 636
Query: 557 TLAKDMPLEEVVKVV--TSTDVAKYPLVE---STESQILVGIVRRAQLVQALKAEP---- 607
L + + +V V+ T+++ +P+VE T+ L G++ R+QL+ LK +
Sbjct: 637 CLRRREKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLKHKVFVER 696
Query: 608 -------------------PSWAP--------GHQQCLQDILAAGCPTEPVTLKLSPETS 640
P + P ++C D+ P+ P T + E S
Sbjct: 697 SNLGLVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEFMNPS-PYT--VPQEAS 753
Query: 641 LHEAHNLFELLNL-HSLFVTSRGRAVGCVS 669
L LF L L H + V +R + VG V+
Sbjct: 754 LPRVFKLFRALGLRHLVVVDNRNQVVGLVT 783
>gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens]
Length = 869
Score = 122 bits (306), Expect = 1e-27
Identities = 128/514 (24%), Positives = 219/514 (42%), Gaps = 72/514 (14%)
Query: 114 ITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLS 173
I P + GSGIPEVK L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMMAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
Query: 227 MSSHFSVWDYWRGFFAATCGAF---------------MFRLLAVFNSEQETITSLYKTSF 271
SS ++ W+ F + F F+L + N + + K
Sbjct: 268 GSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCH 327
Query: 272 RVDVPFDLPEIFFFVALGGLCGILGSAY-LFCQRIFFGFIRNNRFSSKLLATSKPVYSAL 330
+ ++ FFV +G + G+LG+ + +R+ +RN KL+ + + +L
Sbjct: 328 L----WTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSL 383
Query: 331 ATLVLASITYPPSAGRFLASRLSMKQHLDSLFDNHSWAL-MTQNSSPPWPEELDPQHLWW 389
T V+ + A L M S N S+ L +T++ + P
Sbjct: 384 VTTVVVFV-----ASMVLGECRQMSS--SSQIGNDSFQLQVTEDVNSSIKTFFCPN---- 432
Query: 390 EWYHPRFTIF--------------------GTLAFFLVMKFWMLILATTIPMPAGYFMPI 429
+ Y+ T+F TLA F V+ F + I +P+G F+P
Sbjct: 433 DTYNDMATLFFNPQESAILQLFHQDGTFSPVTLALFFVLYFLLACWTYGISVPSGLFVPS 492
Query: 430 FVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH-TISTALLA 488
+ GAA GRL L G I G +AL GAAAF G V TIS ++
Sbjct: 493 LLCGAAFGRLVANVLKSYIGLG--------HIYSGTFALIGAAAFLGGVVRMTISLTVIL 544
Query: 489 FEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVE 548
E T +I + LP+++ ++ A YD V ++ +P L + ++R
Sbjct: 545 IESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHVGLRGVPLLE--WETEVEMDKLRAS 602
Query: 549 HFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLV 582
M ++T + ++ +V ++ +T +P+V
Sbjct: 603 DIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVV 636
>gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens]
Length = 353
Score = 73.2 bits (178), Expect = 8e-13
Identities = 46/142 (32%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 114 ITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLS 173
I P + GSGIPEVK L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMMAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
Query: 227 MSSHFSVWDYWRGFFAATCGAF 248
SS ++ W+ F + F
Sbjct: 268 GSSFWNQGLTWKVLFCSMSATF 289
>gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens]
Length = 308
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 114 ITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLS 173
I P + GSGIPEVK L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMMAAYLGRVRTTTI 188
++ A L + ++ ++
Sbjct: 208 SVVGAGLPQFQSISL 222
>gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens]
Length = 320
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 114 ITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLS 173
I P + GSGIPEVK L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMMAAYLGRVRTTTI 188
++ A L + ++ ++
Sbjct: 208 SVVGAGLPQFQSISL 222
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 30.8 bits (68), Expect = 4.4
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 613 GHQQCLQDILAAGCPTEPVTLKLSPETSLHEA 644
GH CLQ +L CPTE L+ T+LH+A
Sbjct: 99 GHALCLQKLLQYNCPTEHADLQ--GRTALHDA 128
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 30.8 bits (68), Expect = 4.4
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 613 GHQQCLQDILAAGCPTEPVTLKLSPETSLHEA 644
GH CLQ +L CPTE L+ T+LH+A
Sbjct: 112 GHALCLQKLLQYNCPTEHADLQ--GRTALHDA 141
>gi|5032213 solute carrier family 35, member B1 [Homo sapiens]
Length = 322
Score = 30.8 bits (68), Expect = 4.4
Identities = 14/56 (25%), Positives = 31/56 (55%), Gaps = 5/56 (8%)
Query: 280 PEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVL 335
P I + + L GL LG +++F ++FG + ++ T++ ++ LA+++L
Sbjct: 237 PAIIYNILLFGLTSALGQSFIFMTVVYFG-----PLTCSIITTTRKFFTILASVIL 287
>gi|45827690 BTB and CNC homology 1 transcription factor isoform a
[Homo sapiens]
Length = 736
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 583 ESTESQILVGIVRRAQLVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLH 642
E +E++ L G+ L LK + A ++ +D A+ CPTE + P S
Sbjct: 257 ERSENECLGGVPECRDLQVMLKCDESKLAMEPEETKKDP-ASQCPTEKSEVTPFPHNSSI 315
Query: 643 EAHNLFELLNLHS 655
+ H L+ L LH+
Sbjct: 316 DPHGLYSLSLLHT 328
>gi|4502353 BTB and CNC homology 1 transcription factor isoform a
[Homo sapiens]
Length = 736
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 583 ESTESQILVGIVRRAQLVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLH 642
E +E++ L G+ L LK + A ++ +D A+ CPTE + P S
Sbjct: 257 ERSENECLGGVPECRDLQVMLKCDESKLAMEPEETKKDP-ASQCPTEKSEVTPFPHNSSI 315
Query: 643 EAHNLFELLNLHS 655
+ H L+ L LH+
Sbjct: 316 DPHGLYSLSLLHT 328
>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 5 [Homo sapiens]
Length = 896
Score = 30.0 bits (66), Expect = 7.4
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 12/97 (12%)
Query: 411 WMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAG 470
+ L L I + +GYFMP RLF + L I +V G + N G AL G
Sbjct: 107 FFLFLLPPIVLDSGYFMP--------SRLFFDNLGAILTYAVV-GTLWNAFTTGA-ALWG 156
Query: 471 AAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLA 507
+G V + LL F + G ++ A+ +AVLA
Sbjct: 157 LQQ-AGLVAPRVQAGLLDFLLFGSLISAVDP-VAVLA 191
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 29.6 bits (65), Expect = 9.7
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 113 SITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGST 160
++T SSG +G + T+L ++ED +++ KVV + T GST
Sbjct: 1806 NLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGAGST 1853
>gi|19526475 outer dense fiber of sperm tails 3 [Homo sapiens]
Length = 254
Score = 29.6 bits (65), Expect = 9.7
Identities = 16/46 (34%), Positives = 23/46 (50%)
Query: 474 FSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSF 519
F A +H+IS AF V A +L V+ N + ++ QPSF
Sbjct: 116 FDSAPSHSISARTKAFRVDSTPGPAAYMLPMVMGPNTVGKASQPSF 161
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 29.6 bits (65), Expect = 9.7
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 564 LEEVVKVVTSTDVAKYPLVESTESQILVGI----VRRAQLVQALKAEPPSWAPGHQQ 616
++E+ VTS +AK P V+ +++L + R AQ+ Q+L E SW H Q
Sbjct: 3327 VQEIHHYVTS--IAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQ 3381
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 29.6 bits (65), Expect = 9.7
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 468 LAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQS--CQPSFYDGTVI 525
+A AAA G+V + + +VT QI A+ MA L A A+A++ PS+Y+ +
Sbjct: 207 IAAAAATGGSVLNVAALLASGTQVTPQI--AMAAQMAALQAKALAETGIAVPSYYNPAAV 264
>gi|38146109 arginine/serine-rich coiled-coil 2 isoform c [Homo
sapiens]
Length = 202
Score = 29.6 bits (65), Expect = 9.7
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 468 LAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQS--CQPSFYDGTVI 525
+A AAA G+V + + +VT QI A+ MA L A A+A++ PS+Y+ +
Sbjct: 34 IAAAAATGGSVLNVAALLASGTQVTPQI--AMAAQMAALQAKALAETGIAVPSYYNPAAV 91
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 29.6 bits (65), Expect = 9.7
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 468 LAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQS--CQPSFYDGTVI 525
+A AAA G+V + + +VT QI A+ MA L A A+A++ PS+Y+ +
Sbjct: 266 IAAAAATGGSVLNVAALLASGTQVTPQI--AMAAQMAALQAKALAETGIAVPSYYNPAAV 323
>gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]
Length = 362
Score = 29.6 bits (65), Expect = 9.7
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 6/41 (14%)
Query: 606 EPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHN 646
E P+ P H QC L++ PT + P TS H+ HN
Sbjct: 286 ENPNCLPHHHQCFPRRLSSAAPT------VGPLTSYHQYHN 320
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,376,257
Number of Sequences: 37866
Number of extensions: 1069238
Number of successful extensions: 3411
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3320
Number of HSP's gapped (non-prelim): 41
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.