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Search of human proteins with 155722990
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155722990 solute carrier family 4 (anion exchanger), member
1, adaptor protein [Homo sapiens]
(796 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155722990 solute carrier family 4 (anion exchanger), member 1... 1615 0.0
gi|239755020 PREDICTED: similar to solute carrier family 4 (anio... 289 8e-78
gi|239749546 PREDICTED: similar to solute carrier family 4 (anio... 289 8e-78
gi|239743698 PREDICTED: hypothetical protein XP_002342928 [Homo ... 289 8e-78
gi|13699256 protein phosphatase 1 regulatory inhibitor subunit 8... 65 2e-10
gi|21314720 Smad nuclear interacting protein [Homo sapiens] 65 3e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 57 7e-08
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 57 7e-08
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 57 7e-08
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 56 1e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 3e-07
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 55 3e-07
gi|148746195 trichohyalin [Homo sapiens] 55 3e-07
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 54 4e-07
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 54 7e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 53 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 2e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 2e-06
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 51 5e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 49 1e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 1e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 48 3e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 48 3e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens] 47 5e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 5e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 47 5e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 47 5e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 47 5e-05
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 47 9e-05
>gi|155722990 solute carrier family 4 (anion exchanger), member 1,
adaptor protein [Homo sapiens]
Length = 796
Score = 1615 bits (4182), Expect = 0.0
Identities = 796/796 (100%), Positives = 796/796 (100%)
Query: 1 MLAPLRNAPGREGATSPSPPTDATGSLGEWDVDRNVKTEGWVSKERISKLHRLRMADILS 60
MLAPLRNAPGREGATSPSPPTDATGSLGEWDVDRNVKTEGWVSKERISKLHRLRMADILS
Sbjct: 1 MLAPLRNAPGREGATSPSPPTDATGSLGEWDVDRNVKTEGWVSKERISKLHRLRMADILS 60
Query: 61 QSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPP 120
QSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPP
Sbjct: 61 QSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPP 120
Query: 121 PQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGT 180
PQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGT
Sbjct: 121 PQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGT 180
Query: 181 RSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTH 240
RSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTH
Sbjct: 181 RSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTH 240
Query: 241 GTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQ 300
GTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQ
Sbjct: 241 GTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQ 300
Query: 301 ILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQ 360
ILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQ
Sbjct: 301 ILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQ 360
Query: 361 EREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHS 420
EREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHS
Sbjct: 361 EREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHS 420
Query: 421 GKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEK 480
GKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEK
Sbjct: 421 GKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEK 480
Query: 481 KRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFM 540
KRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFM
Sbjct: 481 KRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFM 540
Query: 541 SEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKA 600
SEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKA
Sbjct: 541 SEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKA 600
Query: 601 KKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKE 660
KKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKE
Sbjct: 601 KKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKE 660
Query: 661 KEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDY 720
KEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDY
Sbjct: 661 KEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDY 720
Query: 721 QDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPE 780
QDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPE
Sbjct: 721 QDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPE 780
Query: 781 GQSGDGRTHLNDKYGY 796
GQSGDGRTHLNDKYGY
Sbjct: 781 GQSGDGRTHLNDKYGY 796
>gi|239755020 PREDICTED: similar to solute carrier family 4 (anion
exchanger), member 1, adaptor protein [Homo sapiens]
Length = 210
Score = 289 bits (739), Expect = 8e-78
Identities = 140/145 (96%), Positives = 141/145 (97%)
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
MKGGSKFKLKT T GKLPPK PELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 1 MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
Query: 671 DGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLC 730
DGSLSRPQPEI+PEAAVQEMRPPTDLTHFKE QTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 61 DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
Query: 731 AGPSASKNEYEKSRGELKKKKTPGP 755
AGPSASKNEYEKSRGELKKKKTPGP
Sbjct: 121 AGPSASKNEYEKSRGELKKKKTPGP 145
>gi|239749546 PREDICTED: similar to solute carrier family 4 (anion
exchanger), member 1, adaptor protein [Homo sapiens]
Length = 210
Score = 289 bits (739), Expect = 8e-78
Identities = 140/145 (96%), Positives = 141/145 (97%)
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
MKGGSKFKLKT T GKLPPK PELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 1 MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
Query: 671 DGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLC 730
DGSLSRPQPEI+PEAAVQEMRPPTDLTHFKE QTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 61 DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
Query: 731 AGPSASKNEYEKSRGELKKKKTPGP 755
AGPSASKNEYEKSRGELKKKKTPGP
Sbjct: 121 AGPSASKNEYEKSRGELKKKKTPGP 145
>gi|239743698 PREDICTED: hypothetical protein XP_002342928 [Homo
sapiens]
Length = 210
Score = 289 bits (739), Expect = 8e-78
Identities = 140/145 (96%), Positives = 141/145 (97%)
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
MKGGSKFKLKT T GKLPPK PELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 1 MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
Query: 671 DGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLC 730
DGSLSRPQPEI+PEAAVQEMRPPTDLTHFKE QTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 61 DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
Query: 731 AGPSASKNEYEKSRGELKKKKTPGP 755
AGPSASKNEYEKSRGELKKKKTPGP
Sbjct: 121 AGPSASKNEYEKSRGELKKKKTPGP 145
>gi|13699256 protein phosphatase 1 regulatory inhibitor subunit 8
isoform alpha [Homo sapiens]
Length = 351
Score = 65.5 bits (158), Expect = 2e-10
Identities = 40/125 (32%), Positives = 57/125 (45%), Gaps = 10/125 (8%)
Query: 152 PPYQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSG-CDVCLEHPSVSRYH 210
P + P W G L+ +KG ++ + Y LFGR CD ++H S SR H
Sbjct: 12 PLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVH 71
Query: 211 AVLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGSTR 270
A L + + +L DL STHGTFL R+ P ++ + V FG STR
Sbjct: 72 AALVYH---------KHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTR 122
Query: 271 LFILQ 275
+ L+
Sbjct: 123 AYTLR 127
>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
Length = 396
Score = 64.7 bits (156), Expect = 3e-10
Identities = 52/173 (30%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 154 YQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSG-CDVCLEHPSVSRYHAV 212
Y EPP + L K +L + S L GR D+ ++HPS S+ HAV
Sbjct: 246 YSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAV 305
Query: 213 LQHRA---SGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGST 269
Q+R + DG Y+ DLGS +GTFLN RI P+ Y + V++FG S+
Sbjct: 306 FQYRLVEYTRADGTVGRRVKP-YIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSS 364
Query: 270 RLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSE 322
R ++L D +++K +D DEEEE + S+
Sbjct: 365 REYVLLHESSDTSE-------------------IDRK---DDEDEEEEEEVSD 395
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.3 bits (142), Expect = 1e-08
Identities = 80/444 (18%), Positives = 196/444 (44%), Gaps = 39/444 (8%)
Query: 291 QLKELRKQQQILLEKKMLGEDSDEEEEMDTS--ERKINAGSQDDEMGCTWGMGEDAVEDD 348
Q KELR+Q++ L E+K L E ++ +E + E++ Q+++M W E E +
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM---WRQEERLWEQE 382
Query: 349 AEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDS 408
+ + + + E + +D + + RE E++ + ++ + D
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 409 TGKQLVAEAIHSGKKK-----EAMIQCSLEACRILDTLGLLRQEAVSRKR----KAKNWE 459
K E I +KK E M + + + + + ++ ++R K K WE
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 460 DEDFYDSDDDTFLDRTGLIEKKRL----NRMKKAGKIDEKPETFESLVAKLNDAERELSE 515
E + ++ + + +++ + +M + K+ E+ + K+ D E+++ +
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 516 ISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLI 575
ER++ +Q E + D + E +++ R ++R+E++ ++
Sbjct: 563 QEERMEKKTQE-QEKKTWDQEEKMREE------------ERMREREKKMREEEEMMREQE 609
Query: 576 KIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELP 635
+ ++ E ++++ E + E K ++ ++ + + + K +LP ++ +L
Sbjct: 610 EKMQEQE-EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 636 PTLMRMKDEPEVEEEEE---EEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRP 692
+M+++ +++E+EE E+E+ EK+ +E EKK + + + E E ++MR
Sbjct: 669 EH-EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE---KKMRE 724
Query: 693 PTDLTHFKETQTHENMSQLSEEEQ 716
++ +E + E ++ E+E+
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEE 748
Score = 46.2 bits (108), Expect = 1e-04
Identities = 86/478 (17%), Positives = 195/478 (40%), Gaps = 69/478 (14%)
Query: 278 EEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCT 337
+E+R E E Q++++R+++++ ++K + D+EE+M ER + E
Sbjct: 409 KEERMREQEKMWEQVEKMREEKKMQEQEK---KTRDQEEKMQEEERIREREKKMRE---- 461
Query: 338 WGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEEL--EYEFDEQGHS 395
E+ + EE + Q++ E + ++ K+ Q + E+L + + EQ
Sbjct: 462 ----EEETMREQEE-----KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 396 TWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKA 455
W + K E + +KK + RQE + R+++
Sbjct: 513 IW---------EQEEKIRDQEEMWGQEKK------------------MWRQEKM-REQED 544
Query: 456 KNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSE 515
+ WE E+ + D+ +EKK + KK +EK E ++ + E+++ E
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE----RMREREKKMRE 600
Query: 516 ISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLI 575
E ++ + + E + M E + ++ + +E +E++ +
Sbjct: 601 EEEMMREQEEKMQEQEEK------MQEQEEKMWEQEEKMQEQEEKMWE--QEEKMWEQEE 652
Query: 576 KIVKPAEIPELKKT--ETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPE 633
K+ + +PE K+ E + + K ++ ++ K K + + R E
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 634 --LPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMR 691
+ +M++E E+ E+EE+ +E++EK + +++++ + + E E ++ R
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE---EKMWEQQR 769
Query: 692 PPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKK 749
P E + + ++ E+E+ Q+ + + + EK RG+ +K
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE----EKMRGQEEKMRGQEEKMRGQEEK 823
Score = 38.9 bits (89), Expect = 0.019
Identities = 46/220 (20%), Positives = 97/220 (44%), Gaps = 24/220 (10%)
Query: 509 AERELSEIS-ERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKE 567
A+R + E++ ER S ++ + + + L +E++ L + ++ L EL+++
Sbjct: 195 ADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRK 254
Query: 568 QQRLKGLIKIVKPAEIPE-LKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGK 626
+R K L+ V+ + E + + E + E K +K ++ + + + + G
Sbjct: 255 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW---RQEERLREQEGK--- 308
Query: 627 LPPKRPELPPTLMRMKDEPEVEEE----EEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIE 682
MR ++E +E E+E+E E+EKE E+K+L + + E +
Sbjct: 309 ------------MREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 683 PEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQD 722
++MR + +E + E Q+ E+EQ Q+
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Score = 37.4 bits (85), Expect = 0.055
Identities = 74/408 (18%), Positives = 173/408 (42%), Gaps = 52/408 (12%)
Query: 278 EEDREAESELTVTQLKELRKQQQILLEKKMLGEDS----DEEEEMDTSERKINAGSQDDE 333
+E++ + E Q K++ +Q+++ ++ + E D+E++M E ++ +Q+ E
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 334 MGCTWGMGEDAVEDDA---------EENPIVLE----FQQEREAFYIKDPKKALQGFFDR 380
TW E E++ EE ++ E Q++ E ++ K Q +
Sbjct: 576 KK-TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ---EE 631
Query: 381 EGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDT 440
+ +E E + EQ W ++ +Q H +++ +Q E +
Sbjct: 632 KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE- 690
Query: 441 LGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFE 500
+ E +++++ K W+ E ++++ +R EKK + + +EK + E
Sbjct: 691 ----KMEKKTQEQEKKTWDQEKM--REEESMRER----EKKMREEEEMMREQEEKMQEQE 740
Query: 501 SLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLR 560
K+ + E E+ E E++ + + E Q L ++ + ++K+ +
Sbjct: 741 E---KMQEQEEEMWEQEEKMWEQEEKMWE---QQRLPEQKEKLWEHEKMQ--EQEKIWEQ 792
Query: 561 TFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKG--GSKFK 618
++R ++++++G + ++ E +++ E + G E K ++G + G + K
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQE-EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 619 LKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEK 666
++ G+ MR ++E +EE+ E+EEK + + EK
Sbjct: 852 MEEKMQGQ---------EEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 35.4 bits (80), Expect = 0.21
Identities = 53/307 (17%), Positives = 125/307 (40%), Gaps = 27/307 (8%)
Query: 443 LLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLI--EKKRLNRMKKAGKIDEKPETFE 500
L QE RK++ K W E+ + ++ + ++KRL +K + EK +
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 501 SLVAKLNDAERELSEISERLKASSQVLSESPS-----QDSLDAFMSEMKSGSTLDGVSRK 555
+L + E ++ E E++ + + E ++ L +M+ +
Sbjct: 341 K---ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 556 KLHLRTFELRKEQQRLKGLIK----IVKPAEIPELKKTETQTTGAENKA----------K 601
++ + LR++++R++ K + K E ++++ E +T E K K
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 602 KLTLPLFGAMKGGSKFKLKTGTVGKLPPK---RPELPPTLMRMKDEPEVEEEEEEEEEEE 658
K+ + K + + + + K + LP ++ ++ +++E+EE+ E+E
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Query: 659 KEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNK 718
++ + E+ ++ + R + E E + E K E M + ++E++ K
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Query: 719 DYQDCSK 725
+ K
Sbjct: 578 TWDQEEK 584
Score = 34.7 bits (78), Expect = 0.36
Identities = 84/465 (18%), Positives = 175/465 (37%), Gaps = 95/465 (20%)
Query: 288 TVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERK------------INAGSQDDEMG 335
T+T +EL+K+ L EK L E E +++ E K + + +EM
Sbjct: 217 TITN-EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM- 274
Query: 336 CTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHS 395
W E+ E + + +++ E + ++ + E E + EQ
Sbjct: 275 --WRQEEELREQEKK-------IRKQEEKMWRQEERL----------REQEGKMREQEEK 315
Query: 396 TWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKA 455
W RL + K+L + ++KE L QE ++++
Sbjct: 316 MWRQEKRLREQE---KELREQEKELREQKE-----------------LREQEEQMQEQEE 355
Query: 456 KNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSE 515
K WE E+ ++ +++RL +K + E+ K+ D E + E
Sbjct: 356 KMWEQEEKMREQEEKMWR-----QEERLWEQEKQMREQEQ---------KMRDQEERMWE 401
Query: 516 ISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFE--LRKEQQRLKG 573
ERL+ + + E M E K + +R + E +R+ +++++
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 574 LIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPE 633
+ ++ E K+ E E + ++ LP + K K K+ + +
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLP---------EQKEKLWEQEKMQEQEEK 512
Query: 634 LPPTLMRMKDEPEV--------------EEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQP 679
+ +++D+ E+ E+E++ E+EEK +++ +K ++ + +
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 680 EIEPEAAVQE--MRPPTDLTHFKETQTHENMSQLSEEEQNKDYQD 722
E E + QE MR + +E + E + E+E+ Q+
Sbjct: 573 EQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQE 616
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 57.0 bits (136), Expect = 7e-08
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 179 GTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGS 238
GTR GR C++ L+ SV + HAV+ + AS + + DLGS
Sbjct: 13 GTRHRLPREMIFVGR-DDCELMLQSRSVDKQHAVINYDASTDE---------HLVKDLGS 62
Query: 239 THGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLF-ILQG----PEEDREAESELTVTQLK 293
+GTF+N RIP +TY + + +RFG T LF ++QG PEE + E QL
Sbjct: 63 LNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLS 122
Query: 294 ELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDE 333
+ + ++ DS + + K + +E
Sbjct: 123 QKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEE 162
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo
sapiens]
Length = 1584
Score = 57.0 bits (136), Expect = 7e-08
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 179 GTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGS 238
GTR GR C++ L+ SV + HAV+ + AS + + DLGS
Sbjct: 13 GTRHRLPREMIFVGR-DDCELMLQSRSVDKQHAVINYDASTDE---------HLVKDLGS 62
Query: 239 THGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLF-ILQG----PEEDREAESELTVTQLK 293
+GTF+N RIP +TY + + +RFG T LF ++QG PEE + E QL
Sbjct: 63 LNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLS 122
Query: 294 ELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDE 333
+ + ++ DS + + K + +E
Sbjct: 123 QKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEE 162
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo
sapiens]
Length = 1460
Score = 57.0 bits (136), Expect = 7e-08
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 179 GTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGS 238
GTR GR C++ L+ SV + HAV+ + AS + + DLGS
Sbjct: 13 GTRHRLPREMIFVGR-DDCELMLQSRSVDKQHAVINYDASTDE---------HLVKDLGS 62
Query: 239 THGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLF-ILQG----PEEDREAESELTVTQLK 293
+GTF+N RIP +TY + + +RFG T LF ++QG PEE + E QL
Sbjct: 63 LNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLS 122
Query: 294 ELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDE 333
+ + ++ DS + + K + +E
Sbjct: 123 QKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEE 162
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 56.2 bits (134), Expect = 1e-07
Identities = 84/369 (22%), Positives = 139/369 (37%), Gaps = 58/369 (15%)
Query: 438 LDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDR-TGLIEKKRLNRMKKAGKIDEKP 496
+D + QEA+S ++ +E+ +DS + +D+ T L + +G DE+P
Sbjct: 512 MDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEP 571
Query: 497 ETFESLVAKLNDAERELSEISERLKASS-QVLSES----------PSQDSLDAFMSEMKS 545
E L + + R +E + R + S Q L+E P Q S SE
Sbjct: 572 EELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQ 631
Query: 546 GSTLDGVSRKKLHLRTFELRKEQQRL---KGLIKIVKPAEIPELKKTETQTTGAENKAKK 602
T S LH R+E + + + P E+ L + A
Sbjct: 632 PPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPR-----------AVP 680
Query: 603 LTLPLFGAMKGGSKFKLKTGTVGKL-----------PPKRPELPPTLMRMKDEPEVEEEE 651
L+LP + S ++ + + ++ P+ P P E E EEEE
Sbjct: 681 LSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEE 740
Query: 652 EEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQ--EMRPPTDLTHFKETQTHENMS 709
+EEEEEE E+EE E+++ E+ + E E AAV E+ P S
Sbjct: 741 DEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGP-----------RSGSS 789
Query: 710 QLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK--------TPGPGKLPPT 761
E Q+ + +T L S+ + G+L+ ++ +PG K P
Sbjct: 790 SEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPV 849
Query: 762 LSSKYPEDD 770
+ P+ D
Sbjct: 850 TAELAPDPD 858
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 55.1 bits (131), Expect = 3e-07
Identities = 86/479 (17%), Positives = 204/479 (42%), Gaps = 37/479 (7%)
Query: 279 EDREAESELTVTQLKELRKQQQILLEKKMLGEDSDE-EEEMDTSERKINAGSQDDEMGCT 337
E ++E +L V +LK ++ ++LL ++ L ++D +E+ + K+ A +++E+
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 338 WGMGEDAVEDDAEENPIVLE--FQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHS 395
++ EE E Q++ E ++ K Q R EE+ +E +E+
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 396 TWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKA 455
++++ E +++E M+ E R + + ++E + R+ +
Sbjct: 354 Q--------------EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI-RELEE 398
Query: 456 KNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSE 515
K E E + ++ + ++KR + K + +EK E K+ + E+++
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE---KIREQEKKMWR 455
Query: 516 ISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRK-KLHLRTFELRKEQQRLKGL 574
E++ ++ E Q+ + + E K + +K K+H + ++RK+++++
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 575 IKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPEL 634
+ ++ E ++++ E + E K ++ K + K+ KR E
Sbjct: 516 EEKIREQE-EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE------EEKRQEQ 568
Query: 635 PPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQE----M 690
+ R +++ +EE+ +EE+ ++E ++++ E+ + + E E +QE +
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 691 RPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKK 749
R + +E T E ++ E+E+ C + + + EK R + KK
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKM----CEQEEKMQEQEETMWRQEEKIREQEKK 683
Score = 45.8 bits (107), Expect = 2e-04
Identities = 85/480 (17%), Positives = 192/480 (40%), Gaps = 68/480 (14%)
Query: 274 LQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDE 333
LQ E+ E + L Q +++ +Q++ + E E+ +E+E E++ Q+++
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQEEK 336
Query: 334 MGCTWGMGEDAVEDDAEENPIVLE----FQQEREAFYIKDPKKALQGFFDREGEELEYEF 389
M M + E + ++ E +++ E + K+ K Q E EE E
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 390 DEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKK----------EAMIQCSLEACRILD 439
+E+ H R + K+ E I +K+ E I+ E R +
Sbjct: 397 EEKMHEQEKIR------EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 440 TLGLLRQEAVSRKRKAKN----------WEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKA 489
++E + + K + W E+ ++ + + + E++ R K+
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR-KQE 509
Query: 490 GKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTL 549
K+ + E K+ + E ++ E+++ ++ E + E K
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 550 DGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFG 609
D + R++ +R E + +Q K +++ E + E K K
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEK-------------IREQEEKRQEQEEKMWK------- 609
Query: 610 AMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEE--EEEEKEKEEHEKK 667
+ K++ K+ + ++ +++++ E+ +E+EE+ E+EEK E+ EK
Sbjct: 610 -----QEEKIREQEE-KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663
Query: 668 KLEDGSLSRPQPEI-EPEAAVQE----MRPPTDLTHFKETQTHENMSQLSEEEQNKDYQD 722
+ ++ ++ R + +I E E ++E +R ++ +E + E ++ E+E+ Q+
Sbjct: 664 QEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/440 (19%), Positives = 171/440 (38%), Gaps = 40/440 (9%)
Query: 278 EEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCT 337
EE + E+ + +++R+Q++++ EK+ + +EE M E KI +++M
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEE--KMRRQEEMMWEKEEKIR--ELEEKMHEQ 403
Query: 338 WGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTW 397
+ E + EE E +QE+EA + +K RE EE + EQ W
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI------REQEE---KIREQEKKMW 454
Query: 398 LCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKN 457
++ + ++ + ++E I E R + + QE RK++ K
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMH--EQEEKIRKQEEKV 512
Query: 458 WEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEIS 517
W E+ ++ KI E+ E K+ + E E+
Sbjct: 513 WRQEEKIREQEE---------------------KIREQEEKMWRQEEKIREQE-EMWREE 550
Query: 518 ERLKASSQVLSESPSQDSLDA-FMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIK 576
E++ ++ E Q+ D + E K + V R++ +R E ++++Q K +
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 577 IVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPP 636
K E E K + Q + +K+ + K + + + K E
Sbjct: 611 EEKIREQEE--KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 637 TLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDL 696
T+ R +++ +E++ E+EE+ ++E ++ E+ + + E E +QE
Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728
Query: 697 THFKETQTHENMSQLSEEEQ 716
K + + Q E+ Q
Sbjct: 729 QEEKMWEQEVRLRQQEEKMQ 748
Score = 38.9 bits (89), Expect = 0.019
Identities = 76/426 (17%), Positives = 180/426 (42%), Gaps = 52/426 (12%)
Query: 278 EEDREAESELTVTQLKELRKQQQIL---------LEKKMLGEDS-DEEEEMDTSERKINA 327
EE + E+ + +++R+Q++++ LE+KM ++ E+EE E KI
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
Query: 328 GSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEEL-- 385
+ E E+ + + EE E + R+ I + +K + +E EE+
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQ-EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 386 -EYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLL 444
E + EQ W K+ + E +K+E + E R
Sbjct: 481 QEEKIHEQ-EEIW-----------RQKEKMHEQEEKIRKQEEKVWRQEEKIR-------- 520
Query: 445 RQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVA 504
QE R+++ K W E+ ++ + + + E++++ +K + ++K E
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE--- 577
Query: 505 KLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFEL 564
K+ + E ++ E+++ + E + + E K +K+ + ++
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEK----MWKQEEKIRE-----QEEKIQEQEEKI 628
Query: 565 RKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTV 624
R+++++++ ++ + E ++ + E + E K ++ ++ + K + + +
Sbjct: 629 REQEEKIREQEEMTQEQE-EKMGEQEEKMCEQEEKMQEQEETMW---RQEEKIREQEKKI 684
Query: 625 GKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEI-EP 683
+ K E +M+ ++E E+EE+ E+EEK +E+ EK + ++ + + + +
Sbjct: 685 REQEEKIRE-QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743
Query: 684 EAAVQE 689
E +QE
Sbjct: 744 EEKMQE 749
Score = 35.4 bits (80), Expect = 0.21
Identities = 50/267 (18%), Positives = 114/267 (42%), Gaps = 13/267 (4%)
Query: 487 KKAGKIDEKPETFESLVAKLNDAERELSEIS-ERLKASSQVLSESPSQDSLDAFMSEMKS 545
K AG++++ ++ + A+R + E++ ER S ++ + + + L ++++
Sbjct: 172 KFAGELEQ---ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 228
Query: 546 GSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVK-PAEIPELKKTETQTTGAENKAKKLT 604
L + ++ L EL+++ +R K L+ + AE L K E Q+ A+ +A+
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK-ELQSVSAKLQAQVEE 287
Query: 605 LPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEH 664
L+ + + K+ + K E + + E ++ E+EE+ E+E++
Sbjct: 288 NELWNRLNQQQEEKM-----WRQEEKIQEWEEKIQ--EQEEKIREQEEKIREQEEKMRRQ 340
Query: 665 EKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCS 724
E+ E R Q E+ E + R + +E + +EE+ ++ ++
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Query: 725 KTTSLCAGPSASKNEYEKSRGELKKKK 751
+ E EK R + K+++
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQE 427
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/155 (26%), Positives = 72/155 (46%), Gaps = 14/155 (9%)
Query: 618 KLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRP 677
KL G+ + E P +R++ + ++ EEEEEEEEE+E+++ E++ ++G SR
Sbjct: 238 KLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSRE 297
Query: 678 QPEIE---------PEAAVQEMRPPTDLTHFKETQTHENMSQL--SEEEQNKDY---QDC 723
P ++ P +EM T +E + E + S+EE K + Q
Sbjct: 298 APILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQ 357
Query: 724 SKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKL 758
K + + E + S+G +K K+P P +L
Sbjct: 358 EKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRL 392
Score = 33.1 bits (74), Expect = 1.0
Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 587 KKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPE 646
KK+E + E KL LF K T ++ K E + +++
Sbjct: 1194 KKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERA-KEREKRR 1252
Query: 647 VEEEEEEEEEEEKEKEEHEKKKLE 670
E+EEEE++E EKE E ++LE
Sbjct: 1253 KEQEEEEQKEREKEAERERNRQLE 1276
Score = 30.8 bits (68), Expect = 5.2
Identities = 18/104 (17%), Positives = 42/104 (40%), Gaps = 6/104 (5%)
Query: 622 GTVGKLPP------KRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLS 675
G LPP +RPEL + + + EE+ + ++E+ K E ++ +
Sbjct: 178 GVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAA 237
Query: 676 RPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKD 719
+ +P ++ P+ + + + + EEE+ ++
Sbjct: 238 KLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE 281
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 54.7 bits (130), Expect = 3e-07
Identities = 107/518 (20%), Positives = 209/518 (40%), Gaps = 59/518 (11%)
Query: 274 LQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDE 333
L+ E + + L + KE R++Q+ EK++ + +EEE++ ER ++D
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKEL--QFLEEEEQLQRRERAQQLQEEED- 854
Query: 334 MGCTWGMGEDAVEDDAEEN--------PIVLEFQQEREAFYIK----DPKKALQGFFDRE 381
G+ ED ++E + E ++ R Y K + + Q E
Sbjct: 855 -----GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 382 GEELEYEFDEQGHSTWLCRVRLPVDD--STGKQLVAEAIHSGKKKEAMIQCSLEACRILD 439
EEL+ E E+ R + +QL+ E +++E Q +
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969
Query: 440 TLGLLRQEAVSRKR--KAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPE 497
LL +E R+R + K + +E+ +++ L R +++R ++ K DE +
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL-REEREKRRRQEWERQYRKKDELQQ 1028
Query: 498 TFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKL 557
E L+ + ERE + ER + + ++ L E + L+ RK+
Sbjct: 1029 EEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 558 HLRTFE---LRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGG 614
L+ E LR+E ++ + + + E EL++ E Q E + K+ L +
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL-REEREKRRRQELERQYREE 1143
Query: 615 SKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEE--EEEEEKEKEEHEKKKLEDG 672
+ + + + + P++ + ++E E+++EEE+ EE+EK ++E E++ E+
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 673 SLSRP-----------------QPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEE 715
L R Q E E E AV++ + + + + +E QL E+
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV------YCKGRENEQFRQL-EDS 1256
Query: 716 QNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTP 753
Q +D Q L E E+ R + + + P
Sbjct: 1257 QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Score = 44.3 bits (103), Expect = 5e-04
Identities = 86/443 (19%), Positives = 176/443 (39%), Gaps = 56/443 (12%)
Query: 277 PEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGC 336
PEE++ E + ++ + Q+ EK++L E+ +E+ ++RK
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQE----EKQLLREEREEKRRRQETDRKFRE--------- 1340
Query: 337 TWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHST 396
E+ + + EE P+ +QER DR+ E E EQG
Sbjct: 1341 -----EEQLLQEREEQPLR---RQER----------------DRKFREEELRHQEQGRKF 1376
Query: 397 WLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAK 456
RL + K L E +++E ++ + + L RQE R RK +
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE---RDRKFR 1433
Query: 457 NWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEI 516
E + + FL+ + ++R + ++ ++ ++ E +L+ ER+ +
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE-----QQLHRQERDRKFL 1488
Query: 517 SERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIK 576
E + Q + L + E K + R++ R + +E+Q+L+ +
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ---RQRKFLQEEQQLRRQER 1545
Query: 577 IVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRP--EL 634
+ + + K E + E + ++L+ + KF+L+ V + +R E
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLS-----RQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 635 PPTLMRMKDEPEVEEEEEEE-EEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPP 693
L R + + ++ +E + + E+E+ +E E+++L R E EP+ QE
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660
Query: 694 TDLTHFKETQTHENMSQLSEEEQ 716
++ + E + Q EE+Q
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQ 1683
Score = 42.4 bits (98), Expect = 0.002
Identities = 88/462 (19%), Positives = 184/462 (39%), Gaps = 58/462 (12%)
Query: 274 LQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDS-DEEEEMDTSERKINAGSQDD 332
L+ E + E +L ++ +E R+QQQ+ E++ E EEE + E+++ ++
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE- 678
Query: 333 EMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQ 392
E ++ AEE E +Q RE + PK Q LE E D +
Sbjct: 679 ---------ERREQELAEE-----EQEQARERIKSRIPKWQWQ---------LESEADAR 715
Query: 393 GHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRK 452
S R R G++ E +++E+ +Q E + +QE R+
Sbjct: 716 -QSKVYSRPR----KQEGQRRRQEQEEKRRRRESELQWQEE-----ERAHRQQQEEEQRR 765
Query: 453 RKAKNWEDEDFYDSDDDTFLDRTGLIEKKRL-----NRMKKAGKIDEKPETFESLVAKLN 507
W+ E+ + R L E++ R ++ + + E E +
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
Query: 508 DAERELS--EISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELR 565
+ E+EL E E+L+ + +D L +S +++ ++L
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS------QEQRRDQKWRWQLE 879
Query: 566 KEQQRLKGLIKIVKPAEIPELKK------TETQTTGAENKAKKLTLPLFGAMKGGSKFKL 619
+E++R + + KPA +L+K E + E + K+ + + +
Sbjct: 880 EERKRRRHTL-YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 620 KTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEE---EEEEEKEKEEHEKKKLEDGSLSR 676
+ + + ++ + + + +++++EE+ EE E++ ++E EKK E+ L +
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 677 PQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNK 718
+ ++ E + R + + K+ + + QL EE+ K
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Score = 40.8 bits (94), Expect = 0.005
Identities = 65/388 (16%), Positives = 153/388 (39%), Gaps = 11/388 (2%)
Query: 342 EDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRV 401
ED + + + E Q R + ++ +G E +E + D Q L R
Sbjct: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Query: 402 RLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDE 461
R + ++ E + S K E E R + L L R+ ++++ + +D
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 462 DFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAE-----RELSEI 516
F + ++ + R ++ K+ ++ + + + E + KL E +E +
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 517 SERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIK 576
+RL+ Q+ + + + R++ LR + + +Q+L+ +
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 577 IVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPP 636
+ + +L++ + + + ++ L ++ + + + + +R +
Sbjct: 357 EERREQ--QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Query: 637 TLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRP---QPEIEPEAAVQEMRPP 693
+++ E ++ E+EEE E+K ++E +++L+ R + E E E QE R
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR-K 473
Query: 694 TDLTHFKETQTHENMSQLSEEEQNKDYQ 721
L +E + E +L EEE+ + +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQE 501
Score = 38.5 bits (88), Expect = 0.025
Identities = 95/495 (19%), Positives = 191/495 (38%), Gaps = 63/495 (12%)
Query: 281 REAESELTVTQLKELRKQQQILLEKKMLGEDSD-EEEEMDTSERKINAGSQDDEMGCTWG 339
RE E L + ++L +Q++ ++K L E+ +E D R+ SQ+ E +
Sbjct: 1464 REEEQLLQEREEQQLHRQER---DRKFLEEEQQLRRQERDRKFREQELRSQEPER--KFL 1518
Query: 340 MGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLC 399
E + + + E QQ R + ++ F RE E+L E +EQ
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF-REEEQLRQEREEQ------- 1570
Query: 400 RVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWE 459
+L + K + E +++E + R + LRQE R RK + E
Sbjct: 1571 --QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE---RDRKFR--E 1623
Query: 460 DEDFYDSDDDTFL-----DRTGLIEKKRLNRMKKAGKI-DEKPETFESLVAKLNDAEREL 513
DE ++ L DR L E+ +L R ++ ++ ++ F L + E +
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Query: 514 SEISERLKASSQVLSESPSQDSLDAFMSEMKS--GSTLDGVSRKKLHLRTFELRKEQQRL 571
ER + + + Q+ F+ E + L+ R++ LR +++ +R
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743
Query: 572 KGLIKIVKPAEI-PELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPK 630
+ KI++ ++ PE ++ + + + K ++ +L +
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEE---------------------QLRQE 1782
Query: 631 RPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEM 690
R E +++ + + EEE+ ++ +E+ + + DG + +++ E Q +
Sbjct: 1783 REE-----QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
Query: 691 RPPTDLTHFKETQ-------THENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKS 743
R D + E Q E EEEQ + + K + + +
Sbjct: 1838 RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Query: 744 RGELKKKKTPGPGKL 758
GE+K ++ G G+L
Sbjct: 1898 VGEIKSQEGKGHGRL 1912
Score = 38.1 bits (87), Expect = 0.032
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Query: 637 TLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDL 696
T++R ++E EEE + + E ++EE + +KLE L R + E E + Q +R L
Sbjct: 251 TVLRKEEEKLQEEEPQR--QRELQEEEEQLRKLERQELRRERQEEEQQQ--QRLRREQQL 306
Query: 697 THFKETQTHENMSQLSEEEQNKDYQD 722
+E + E + E+++ ++ Q+
Sbjct: 307 RRKQEEERREQQEERREQQERREQQE 332
Score = 37.7 bits (86), Expect = 0.042
Identities = 78/446 (17%), Positives = 179/446 (40%), Gaps = 80/446 (17%)
Query: 281 REAESELTVTQLK---ELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQ---DDEM 334
RE E E QL+ +LR++QQ+ E+++ E E+ E+++ Q + ++
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 335 GCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGH 394
+ + E L+ +QE ++K ++ + +R ++L+ + +E+
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 395 STWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRK 454
WL +L ++ +Q +++E ++ E R L RQE R ++
Sbjct: 486 ERWL---KLEEEERREQQ---------ERREQQLRREQEERR---EQRLKRQEEEERLQQ 530
Query: 455 AKNWEDEDFYDSDD--DTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERE 512
E + + ++ + L R E+KRL + ++ ++ + E + K + R+
Sbjct: 531 RLRSEQQLRREQEERREQLLKRE---EEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 513 LSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLK 572
+RLK + E + + L+ R++ L+ E +E+++
Sbjct: 588 -----QRLKREQEERLEQ---------RLKREEVERLEQEERREQRLKREEPEEERRQ-- 631
Query: 573 GLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRP 632
+++K E E ++ + + E + ++L KR
Sbjct: 632 ---QLLKSEEQEERRQQQLRREQQERREQRL--------------------------KRE 662
Query: 633 ELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRP 692
E R++ + E EEE E+E E+E+ + ++ + + Q ++E EA ++ +
Sbjct: 663 EEEE---RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 693 PTDLTHFKETQTHENMSQLSEEEQNK 718
+ + E + E+E+ +
Sbjct: 720 ------YSRPRKQEGQRRRQEQEEKR 739
Score = 37.7 bits (86), Expect = 0.042
Identities = 81/453 (17%), Positives = 182/453 (40%), Gaps = 50/453 (11%)
Query: 281 REAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGM 340
+E E +L + ++ R+++Q L ++ + +EE+++ ER+ ++ ++
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR----- 1456
Query: 341 GEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCR 400
++ EE ++ E ++E++ + +K L+ +E + +F EQ
Sbjct: 1457 -QERHRKFREEEQLLQE-REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ-------- 1506
Query: 401 VRLPVDDSTGKQLVAEA-IHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNW- 458
L + K L E +H +++ +Q + L RQE ++R+ ++
Sbjct: 1507 -ELRSQEPERKFLEEEQQLHRQQRQRKFLQ---------EEQQLRRQERGQQRRQDRDRK 1556
Query: 459 --EDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEI 516
E+E ++ L R K RL K + E+ + + + +++L +
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 517 SER-LKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQR-LKGL 574
+R + Q+L E Q + + L+ + + R +LR ++ R +
Sbjct: 1617 RDRKFREDEQLLQEREEQQ----LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 575 IKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPEL 634
++++ E +L++ E E + + + KF + + + +R
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQ------LRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 635 PPTLMRMKDEPEVEEEEE------EEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQ 688
+R + E E +E EEE+ E+EE + ++ E R + ++ E Q
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 689 EMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQ 721
++R F+E E + Q EE+Q + Q
Sbjct: 1787 QLRSQESDRKFRE---EEQLRQEREEQQLRPQQ 1816
Score = 36.6 bits (83), Expect = 0.094
Identities = 83/449 (18%), Positives = 170/449 (37%), Gaps = 73/449 (16%)
Query: 277 PEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGC 336
PE+ R E E + +EL+++++ LL ++ + +E + RK + Q++E
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREE---REKRRRQEWERQYRKKDELQQEEEQ-- 1032
Query: 337 TWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHST 396
+ ++ E+ + QERE Y RE EEL+ E +
Sbjct: 1033 -------LLREEREKRRL-----QERERQY-------------REEEELQQEEE------ 1061
Query: 397 WLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAK 456
QL+ E + +++E Q E + LLR+E R+R+ +
Sbjct: 1062 ---------------QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 457 NW---EDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAEREL 513
E+E+ ++ + EK+R +++ + +E+ + E + + +R
Sbjct: 1107 ERQCREEEELQQEEEQLLREER---EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 514 SEISERLKASSQVLSESPS---QDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQR 570
E+ + + ++ E ++ + + + R+K R R E QR
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK---RKQRYRDEDQR 1220
Query: 571 LKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPK 630
L +P + ++ + G EN+ + ++ + +G+ +
Sbjct: 1221 -SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED--SQLRDRQSQQDLQHLLGEQQER 1277
Query: 631 RPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEM 690
E + +D EEE+ E EE+KE + ++K E+ L R + E +
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLE-REEQKEAKRRDRKSQEEKQLLREERE------EKRR 1330
Query: 691 RPPTDLTHFKETQTHENMSQLSEEEQNKD 719
R TD +E Q + + Q +D
Sbjct: 1331 RQETDRKFREEEQLLQEREEQPLRRQERD 1359
Score = 35.0 bits (79), Expect = 0.27
Identities = 91/505 (18%), Positives = 186/505 (36%), Gaps = 99/505 (19%)
Query: 275 QGPEEDREAESELTVTQLKELRK-------QQQILLEKKMLGEDSDEEEEMDTSERKINA 327
Q E +E E +L + +ELR+ QQQ L ++ L +EE ER+
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 328 GSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEY 387
++ + ++ E + E ++ RE ++ ++ +R ++L
Sbjct: 326 ERREQQ-------------EERREQQLRREQEERREQQLRREQEE------ERREQQLRR 366
Query: 388 EFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQE 447
E +E+ L R + QL E +++ Q ++ L R++
Sbjct: 367 EQEEERREQQLRREQ---------QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 448 AVSRKRKAKNWEDEDFYDSDDDT----------------FLDRTGLIEKKRLNRMKKAGK 491
+ R+++ + ++E+ ++ + +L R E+ R K+ K
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 492 IDEKPETFESLVAKLNDAERELSEISER-LKASSQVLSES--PSQDSLDAFMSEMKSGST 548
D++ E E + + RE E E+ L+ + E Q+ + ++S
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 549 L---DGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTL 605
L R++L R E R EQ+R + +K + +L K E E + ++L
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE-----ERRQQRL-- 590
Query: 606 PLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHE 665
KR + R+K E EVE E+EE E++ K E
Sbjct: 591 ------------------------KREQEERLEQRLKRE-EVERLEQEERREQRLKREEP 625
Query: 666 KKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSK 725
+++ L + E + ++ + K + E + Q + E ++ ++
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE--- 682
Query: 726 TTSLCAGPSASKNEYEKSRGELKKK 750
++ E E++R +K +
Sbjct: 683 -------QELAEEEQEQARERIKSR 700
Score = 31.2 bits (69), Expect = 4.0
Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 641 MKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTH-- 698
+K E E E E+E +++ ++++ E+++ L + + E Q++R +
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 699 -FKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK 751
K + E + Q EQ + + L + E E+ LK+++
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ 571
Score = 30.8 bits (68), Expect = 5.2
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 644 EPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFK--E 701
E EE+E +EEE+++ + ++KL + + R Q E + V E++ H + E
Sbjct: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLE 1914
Query: 702 TQTHE 706
TH+
Sbjct: 1915 PGTHQ 1919
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 54.3 bits (129), Expect = 4e-07
Identities = 60/248 (24%), Positives = 103/248 (41%), Gaps = 18/248 (7%)
Query: 467 DDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLK----- 521
++ T L + ++KK +K K EK E K D +E ++ E+ K
Sbjct: 510 EEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETG 569
Query: 522 -ASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKP 580
+ E ++ D + ++K +D + K L E K + + K K K
Sbjct: 570 RETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKD 629
Query: 581 AEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMR 640
+ E +K + + G E+K K PL K + T ++P P L P L
Sbjct: 630 KDKREKEKVKDK--GREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPE 687
Query: 641 MKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFK 700
++ EE+E+ +E+EK+K++ EKKK ++ + + E E E +E R K
Sbjct: 688 -----KLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKE-----K 737
Query: 701 ETQTHENM 708
E HE +
Sbjct: 738 EKHKHEKI 745
Score = 38.1 bits (87), Expect = 0.032
Identities = 51/246 (20%), Positives = 103/246 (41%), Gaps = 19/246 (7%)
Query: 523 SSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAE 582
SS +S + + + K S+++ + K L+T +KE+QR + K +
Sbjct: 493 SSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDK 552
Query: 583 IPELKKTETQTTGAEN-KAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRM 641
E K + + E + K F + +K K + PK +L L+R
Sbjct: 553 SKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPK-VKLKDGLVR- 610
Query: 642 KDEPEVEEEEEEEEEEEKEKEEHEKKKLED----GSLSRPQPEI---EPEAAVQEMRPPT 694
K++ + ++++++ E+ +K+K++ EK+K++D + P P + E A+ P T
Sbjct: 611 KEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPAT 670
Query: 695 ---------DLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRG 745
L + E ++ E+E+ KD ++ K + E EK
Sbjct: 671 ASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKRER 730
Query: 746 ELKKKK 751
E ++K+
Sbjct: 731 EKREKE 736
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
sapiens]
Length = 1554
Score = 53.5 bits (127), Expect = 7e-07
Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 20/165 (12%)
Query: 197 CDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCR 256
C++ L+ SV + HAV+ + D + ++ DLGS +GTF+N RIP + Y
Sbjct: 30 CELMLQSRSVDKQHAVINY---------DQDRDEHWVKDLGSLNGTFVNDMRIPDQKYVT 80
Query: 257 VHVGHVVRFGGSTRLFILQG-----PEEDREAE---SELTVTQLKELRKQQQILLEKKML 308
+ + V+RFG + +++L+ PEE + E S+L V+ K+ + L E
Sbjct: 81 LKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKRSEALPEHTPY 140
Query: 309 GEDSDEEEEMDTSERKINAGSQDDEM---GCTWGMGEDAVEDDAE 350
E S+ E A S + WG + + DA+
Sbjct: 141 CEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQ 185
Score = 35.8 bits (81), Expect = 0.16
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 9/77 (11%)
Query: 41 WVSKERISKLHRLRMADILSQS----ETLASQDLSGDFKKPALPVSPAARSKAPASSSSN 96
W S+ER L L +D+++ + E + L K A P SPAAR + SS+S+
Sbjct: 1043 WPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASS 1102
Query: 97 PEEVQKEGPTALQDSNS 113
++GP AL SNS
Sbjct: 1103 -----QKGPQALTRSNS 1114
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 52.8 bits (125), Expect = 1e-06
Identities = 47/160 (29%), Positives = 71/160 (44%), Gaps = 24/160 (15%)
Query: 625 GKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPE 684
G P +L + DE E EEEEEEEEEEE+E+EE + ++ E+ + E E E
Sbjct: 869 GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928
Query: 685 AAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSR 744
+E + E +L EEE+ +D ++ + + E+ +
Sbjct: 929 EEFEE-------------EFEEEEGELEEEEEEEDEEEEEELEEV------EDLEFGTAG 969
Query: 745 GELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPEGQSG 784
GE+ ++ P P LPP L PE P V PE + G
Sbjct: 970 GEV-EEGAPPPPTLPPALPP--PESPPK--VQPEPEPEPG 1004
Score = 30.8 bits (68), Expect = 5.2
Identities = 36/152 (23%), Positives = 54/152 (35%), Gaps = 44/152 (28%)
Query: 616 KFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEE-----EEEEKEKEEH------ 664
+F G V + P P LPP L + P+V+ E E E E EE EE
Sbjct: 964 EFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023
Query: 665 ------------EKKKLEDGSLSRPQP---------------EIEPEAAVQEMRPPTDLT 697
E ++ + + P P E E E +++PP +
Sbjct: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
Query: 698 HFKETQTHENMSQLSEEEQN------KDYQDC 723
+E +T L E+EQ+ D+ DC
Sbjct: 1084 AEEEMETETEAEALQEKEQDDTAAMLADFIDC 1115
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.4 bits (124), Expect = 2e-06
Identities = 89/482 (18%), Positives = 195/482 (40%), Gaps = 63/482 (13%)
Query: 278 EEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTS--ERKINAGSQDDEMG 335
EE + + Q KELR+Q++ L E+K L E ++ +E + E++ Q+++M
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM- 333
Query: 336 CTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHS 395
W E E + + + + + E + +D + + RE E++ +E +E+
Sbjct: 334 --WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM-WEQEEKMQE 390
Query: 396 TWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKA 455
R R ++ + E + +++E +Q E + +Q +K K
Sbjct: 391 EERIRER--------EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 456 KNWEDEDFYDSDDDTFLDRTGLIEKKRL----NRMKKAGKIDEKPETFESLVAKLNDAER 511
WE E + ++ + + +++ + +M + K+ E+ + K+ D E+
Sbjct: 443 --WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 512 ELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRL 571
++ + ER+ + LR++++R+
Sbjct: 501 KMWDQEERMWEQDE-------------------------------------RLREKEERM 523
Query: 572 KGLIKIVKPAE-IPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPK 630
+ K+ + E + E KKT+ Q ++ +K+ M+ K + + + +
Sbjct: 524 REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE--ERMREREKKMREEEEMMREQEE 581
Query: 631 RPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEK---KKLEDGSLSRPQPEIEPEAAV 687
+ + MR ++E E+EE+ +E+EEK E+ EK ++ ED + + E E +
Sbjct: 582 KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
Query: 688 QEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGEL 747
QE K + E M + E+ Q ++ + + + + + EK RG+
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 748 KK 749
+K
Sbjct: 702 EK 703
Score = 36.2 bits (82), Expect = 0.12
Identities = 72/418 (17%), Positives = 158/418 (37%), Gaps = 104/418 (24%)
Query: 278 EEDREAESELTVTQLKELRKQQQIL-LEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGC 336
+E + + E Q +++R Q+++ EKKM ++ E+E E++ Q+ +M
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM-- 502
Query: 337 TWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHST 396
W E E D L ++ER +++ KK Q E E + EQ T
Sbjct: 503 -WDQEERMWEQDER-----LREKEER----MREQKKMWQ---QEEKMREEKKTQEQEKKT 549
Query: 397 WLCRVRLPVDDSTGKQLVAEAIHSGKKK----EAMIQCSLEACRILDTLGLLRQEAVSRK 452
W D K E + +KK E M++ E + QE R+
Sbjct: 550 W---------DQEEKMREEERMREREKKMREEEEMMREQEEKMQ--------EQEEKMRE 592
Query: 453 RKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERE 512
++ K WE E+ ++ + +++++ ++ K+ E+ E K+ + E +
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWE-----QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 513 LSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLK 572
+ E E+++ + + E +K+ + ++R+++++++
Sbjct: 648 MWEQEEKMREQEEKMREQ-----------------------EEKMQGQEEKMREQEEKMQ 684
Query: 573 GLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRP 632
G + ++ E +++ E + G E K ++G
Sbjct: 685 GQEEKMREQE-EKMRGQEEKMWGQEEKMWGQEEKMWG----------------------- 720
Query: 633 ELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEM 690
+EE E+EE ++++E +++L + +P + P + M
Sbjct: 721 ---------------QEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNM 763
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 52.0 bits (123), Expect = 2e-06
Identities = 80/385 (20%), Positives = 144/385 (37%), Gaps = 65/385 (16%)
Query: 451 RKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEK------PETFESLVA 504
+K+K + + + F D+D + D+ +K +++ D+ P+ +
Sbjct: 96 KKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQ 155
Query: 505 KLN---DAERELSEISERLKASSQVLSESPSQDSLDAFMSEMK---------------SG 546
K N D E + S+++K S++ S S D D F+ K SG
Sbjct: 156 KSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESG 215
Query: 547 STLDG-------VSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENK 599
+ D V++KK + E +K + L K+ + E+ KK +++ ++ K
Sbjct: 216 NEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRK 275
Query: 600 AKKLTLPLFGAMKGG----SKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEE--- 652
++ T+ + G S+ K +T T + + + + K E E +E+E+
Sbjct: 276 FEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKG 335
Query: 653 -----------------EEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTD 695
EEEE +K +EE K+LE+ R E E QE R
Sbjct: 336 PSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK----EEERLEQEKRERKK 391
Query: 696 LTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSA---SKNEYEKSRGELKKKKT 752
+ + + +L + Q + T L SK+ K R + KK
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451
Query: 753 PGPGKLPPTLSSKYPEDDPDYCVWV 777
K+P L SK + + C V
Sbjct: 452 K---KIPQQLESKEVSESMELCAAV 473
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/312 (21%), Positives = 119/312 (38%), Gaps = 54/312 (17%)
Query: 479 EKKRLNRMKKAGKIDEKPETFESLVAKLNDAE-RELSEISERLKASSQVLSESPSQDSLD 537
EK+ + KK G + + +AKL + E R+ E ER+K ++ ++ ++ L+
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE 383
Query: 538 AFMSEMKSGSTLDGVSRKKLH--LRTFELRKEQQRLKGLIKIVKP--AEIPELKKTETQT 593
E K + R K L T R+ + R + +K+++ E+P +
Sbjct: 384 QEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR 443
Query: 594 TGAENKAKKLTLPLFGAMKGGSKFKLKTGT--VGKLPPKRPELPPTL------------- 638
E+K +K + + +L + + P++ E PP +
Sbjct: 444 PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL 503
Query: 639 ---------------------MRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRP 677
+ +K+ PE EEEEEEEEEE++E EE E+ E+G
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE---EEGESEGS 560
Query: 678 QPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASK 737
+ + E E E L + + S++++ K+ + K +K
Sbjct: 561 EGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDK----------AK 610
Query: 738 NEYEKSRGELKK 749
EK R E K
Sbjct: 611 RRIEKRRLEHSK 622
Score = 38.5 bits (88), Expect = 0.025
Identities = 67/342 (19%), Positives = 143/342 (41%), Gaps = 59/342 (17%)
Query: 449 VSRKRKAKNWEDEDFYDSDDDTF---LDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAK 505
+ +K+K K+ ED D D D ++ G +++ + K K ++K + F+
Sbjct: 1 MGKKQKNKS-EDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDE---- 55
Query: 506 LNDAERELSEIS---ERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTF 562
+D +EL E+S + +KA + ++ P++++ + F S+ K G + +
Sbjct: 56 -DDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSE 114
Query: 563 ELRKEQQRLKGLIKIVKPA--------------EIPELKKTETQTT-----GAE------ 597
EL + + K K KP ++P+ K + Q + G+E
Sbjct: 115 ELEDKDSKSK---KTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNS 171
Query: 598 NKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEE 657
K K+ + G + G+ ++ + P + ++ + + + ++
Sbjct: 172 KKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231
Query: 658 EKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQN 717
+ EK+E E+KK + E +A +++++ +L K+ Q+ + SQ EE+
Sbjct: 232 KAEKKERERKKRD-----------EEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEET 280
Query: 718 KDYQDCSKTTSLCAG------PSASK--NEYEKSRGELKKKK 751
+ T + A P+A++ NE +K + + KKKK
Sbjct: 281 VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK 322
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 50.8 bits (120), Expect = 5e-06
Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 15/151 (9%)
Query: 625 GKLPPK-RPELPPTLMRMKD-------EPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSR 676
GK P + RPE P L + ++ E E E EEEEEEEEE E+EE K+++E+ R
Sbjct: 1743 GKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEER 1802
Query: 677 PQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSAS 736
+ E + A P + + Q + ++ + +EEQ +D ++ + A +
Sbjct: 1803 DEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEA 1862
Query: 737 KNE-------YEKSRGELKKKKTPGPGKLPP 760
E E SRGE+ P LPP
Sbjct: 1863 LLENMIQNILVEASRGEVVLTSRPRVIALPP 1893
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 49.3 bits (116), Expect = 1e-05
Identities = 120/553 (21%), Positives = 221/553 (39%), Gaps = 91/553 (16%)
Query: 282 EAESELTVTQLKELRKQQQILLEKKM--LGEDSDEEEEMDTS--------ERKINAGSQD 331
E E+ + + E + +ILLE K+ L E +EEEEM++ E K ++ +D
Sbjct: 898 ETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRD 957
Query: 332 -DEMGCTWGMGEDAVEDDAEENPIVLEFQQ----EREAFYIKDPKKALQGFFDREGEELE 386
D++ T E E A EN + ++ E + KK+LQ + ++L+
Sbjct: 958 IDDLELTLTKVEK--EKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQ 1015
Query: 387 YEFDE-QGHSTWLCRVRLPVDDSTG-----KQLVAEAIHSGKKKEAMIQCSLEACRILDT 440
E D+ G ++ DD G K+L A+ + +K E ++ S E+ L+
Sbjct: 1016 VEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEN 1075
Query: 441 LGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFE 500
++ + K K K +E DD + +KK + +++E+ E
Sbjct: 1076 ----DKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQF-QKKIKELQARIEELEEEIEAEH 1130
Query: 501 SLVAKL----NDAERELSEISERLKASSQVLS-------------ESPSQDSLDAFMSEM 543
+L AK+ +D REL EISERL+ +S S + +D +A +
Sbjct: 1131 TLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHE 1190
Query: 544 KSGSTL-----DGVS------------RKKLHLRTFELRKEQQRLKGLIKIVKPAEIPEL 586
+ +TL D V+ ++KL EL+ E + I+ + ++ +
Sbjct: 1191 ATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSK-SNI 1249
Query: 587 KKT----ETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMK 642
++T E Q + + K ++ T + ++ + + G + ++ L L + K
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309
Query: 643 D--EPEVEEEEEEEEEEEKEK------------------EEHEKKKLEDGSLSRPQPEIE 682
++EE + + EEE K K E++E+++ L R +
Sbjct: 1310 QALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKAN 1369
Query: 683 PEAAVQEMRPPTDL---THFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNE 739
E A + TD T E + +L E E+N + + SK SL + E
Sbjct: 1370 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETAN-SKCASLEKTKQRLQGE 1428
Query: 740 YEKSRGELKKKKT 752
E +L++ T
Sbjct: 1429 VEDLMRDLERSHT 1441
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/127 (27%), Positives = 62/127 (48%)
Query: 566 KEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVG 625
+E++ K ++++ A E ++ E +T A ++ + + + TG G
Sbjct: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERG 1059
Query: 626 KLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEA 685
+L E +DE E EEEEEEEE+EE+E+EE E+++ E+ S P+
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
Query: 686 AVQEMRP 692
A++ RP
Sbjct: 1120 AIKRKRP 1126
Score = 48.1 bits (113), Expect = 3e-05
Identities = 96/467 (20%), Positives = 169/467 (36%), Gaps = 62/467 (13%)
Query: 278 EEDREAESELT--VTQLKELRKQQQILLEKKMLGEDS-----DEEEEMDTSERKINAGSQ 330
EE+REAE E + Q K++Q +L + S + + + + E + G +
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
Query: 331 DDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFD 390
+ + E+ E++ EE E ++E E E EE E E +
Sbjct: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDE----------------EEEEEEEEEEE 1102
Query: 391 EQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVS 450
E+ + R+ P + ++ +K I S+ I +T +L
Sbjct: 1103 EENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVL------ 1156
Query: 451 RKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAE 510
+E F +SD++ + + +E +++ G+ + F+ K E
Sbjct: 1157 ---------NEPFDNSDEERPMPQ---LEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTE 1204
Query: 511 RELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLD------------GVSRKKLH 558
E + + K + P +++++ S +K GS + G R
Sbjct: 1205 EEEGKDNHCFK------NADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSK 1258
Query: 559 LRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFK 618
R + RK +L P E E E Q +E K + + +K +
Sbjct: 1259 WRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEAL 1318
Query: 619 LKTGTVGKLPPKRPELPPTLMRMKDEPEV---EEEEEEEEEEEKEKEEHEKKKLEDGSLS 675
L + P P T K E ++ EEEEEEEEEEE+E+EE E ++ E G
Sbjct: 1319 LPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNV 1378
Query: 676 RPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQD 722
P+ +E T+ HE + EE + + D
Sbjct: 1379 EKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHD 1425
Score = 45.1 bits (105), Expect = 3e-04
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 5/102 (4%)
Query: 628 PPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE-DGSLSRPQPEIEPEAA 686
P ++PE L++ ++E E EEEEEEEEEEE+ +EE +E D ++ Q + EPE +
Sbjct: 1339 PGEKPE--DDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEIS 1396
Query: 687 VQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTS 728
++ H +E + E S E+ + D +D S S
Sbjct: 1397 TEKEDSARLDDHEEEEEEDEEPSH--NEDHDADDEDDSHMES 1436
Score = 31.6 bits (70), Expect = 3.0
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 12/53 (22%)
Query: 642 KDEPEVE------------EEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIE 682
K+EPE+ EEEEEE+EE E+H+ +D + + E E
Sbjct: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442
Score = 31.2 bits (69), Expect = 4.0
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 645 PEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQT 704
PE +EE E+ +K+ +++ K E + +E P T + Q
Sbjct: 1500 PESDEEPPPGEQAQKQDQKNSK---------------EVDTEFKEGNPATMEIDSETVQA 1544
Query: 705 HENMSQLSEEEQNKDYQDCSKTTSLC 730
++++Q S E Q+ +QDC++T C
Sbjct: 1545 VQSLTQESSE-QDDTFQDCAETQEAC 1569
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 48.1 bits (113), Expect = 3e-05
Identities = 129/594 (21%), Positives = 224/594 (37%), Gaps = 148/594 (24%)
Query: 279 EDREAESELTVTQLKELRKQQQILLEKKMLGED--------SDEEEEMDTSERKINAGSQ 330
++R + E +++EL++ Q+LLE K + ED SD+ E++ ++ A
Sbjct: 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLH 392
Query: 331 DDEMGCTWGMGEDAVEDDAEENPIVLEFQQER---EAFYI----------KDPKKALQGF 377
D EM M +E+ EEN + LE Q++ E+ ++ + +A Q
Sbjct: 393 DMEM--ERDMDRKKIEELMEEN-MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKS 449
Query: 378 FDREGEE------LEYEFDEQGHSTWLCRVRLPVDDSTG--------------------- 410
E E L+ E + Q + + +R VD G
Sbjct: 450 LGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEI 509
Query: 411 -------------------KQLVAEAIHSGKKKEAMIQCSLEACRILD--------TLGL 443
K L+ E K E + + S +IL+ T+
Sbjct: 510 LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Query: 444 LRQEA-VSRKRKAKNWEDED--FYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFE 500
LRQ + +S + + K+ E E+ ++S +T + IE ++ K+ EK E E
Sbjct: 570 LRQRSQISAEARVKDIEKENKILHESIKET-SSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 501 SLVAKLNDAERE----------LSEISERLKASSQVLSESPSQD-----SLDAFM----- 540
L +L+ E+E L E+++A Q SE ++ +LD+F
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 688
Query: 541 --SEMKSGSTLD----------------GVSRKKLHLRTFELRKEQQRLKGLIKIVKPAE 582
S K S LD + +L L EL E+++LK ++++K A
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLK-AS 747
Query: 583 IPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMK 642
+ ++ E G + + ++L L + K K + + L + L L +K
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLEMENQTLQKNLEELK 804
Query: 643 DEPEVEEEEEEEE---EEEKEKEEHEKKKLE-DGSLSRPQPEIEPEAAVQEMRPPTDLTH 698
+ E+ E+E E+E + E +KK+LE + R Q EI
Sbjct: 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI----------------- 847
Query: 699 FKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKT 752
K+T EN ++ E K+ + SK + E EK EL K+ T
Sbjct: 848 -KDTTLEENNVKIGNLE--KENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 48.1 bits (113), Expect = 3e-05
Identities = 129/594 (21%), Positives = 224/594 (37%), Gaps = 148/594 (24%)
Query: 279 EDREAESELTVTQLKELRKQQQILLEKKMLGED--------SDEEEEMDTSERKINAGSQ 330
++R + E +++EL++ Q+LLE K + ED SD+ E++ ++ A
Sbjct: 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLH 392
Query: 331 DDEMGCTWGMGEDAVEDDAEENPIVLEFQQER---EAFYI----------KDPKKALQGF 377
D EM M +E+ EEN + LE Q++ E+ ++ + +A Q
Sbjct: 393 DMEM--ERDMDRKKIEELMEEN-MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKS 449
Query: 378 FDREGEE------LEYEFDEQGHSTWLCRVRLPVDDSTG--------------------- 410
E E L+ E + Q + + +R VD G
Sbjct: 450 LGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEI 509
Query: 411 -------------------KQLVAEAIHSGKKKEAMIQCSLEACRILD--------TLGL 443
K L+ E K E + + S +IL+ T+
Sbjct: 510 LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Query: 444 LRQEA-VSRKRKAKNWEDED--FYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFE 500
LRQ + +S + + K+ E E+ ++S +T + IE ++ K+ EK E E
Sbjct: 570 LRQRSQISAEARVKDIEKENKILHESIKET-SSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 501 SLVAKLNDAERE----------LSEISERLKASSQVLSESPSQD-----SLDAFM----- 540
L +L+ E+E L E+++A Q SE ++ +LD+F
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 688
Query: 541 --SEMKSGSTLD----------------GVSRKKLHLRTFELRKEQQRLKGLIKIVKPAE 582
S K S LD + +L L EL E+++LK ++++K A
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLK-AS 747
Query: 583 IPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMK 642
+ ++ E G + + ++L L + K K + + L + L L +K
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLEMENQTLQKNLEELK 804
Query: 643 DEPEVEEEEEEEE---EEEKEKEEHEKKKLE-DGSLSRPQPEIEPEAAVQEMRPPTDLTH 698
+ E+ E+E E+E + E +KK+LE + R Q EI
Sbjct: 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI----------------- 847
Query: 699 FKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKT 752
K+T EN ++ E K+ + SK + E EK EL K+ T
Sbjct: 848 -KDTTLEENNVKIGNLE--KENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 47.4 bits (111), Expect = 5e-05
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 638 LMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLT 697
++ ++E E EEEEEEEEEE++E+EE E+++ E+ + E E E +E P +
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI- 312
Query: 698 HFKETQTHENMSQLSE 713
F+E +H + + E
Sbjct: 313 -FQEDTSHTSAQKAPE 327
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/72 (36%), Positives = 39/72 (54%)
Query: 642 KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKE 701
++E E +EEEEEEEEEE+E+EE E+++ E+ + E P+ QE T E
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
Query: 702 TQTHENMSQLSE 713
+ E+ S E
Sbjct: 328 LRGPESPSPKPE 339
Score = 35.8 bits (81), Expect = 0.16
Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 7/205 (3%)
Query: 486 MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKS 545
+K A DE T E A+ + + E + S V S S A S S
Sbjct: 99 VKDASVSDESEGTLEGAEAETSGQDE--IHRPETAEGRSPVKSHFGSNPIGSATASSKGS 156
Query: 546 GSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAE-IPELKKTETQTTGAENKAKKLT 604
S+ G+ L L ++ +E + L + KP I L + + +E K L
Sbjct: 157 YSSYQGIIATSL-LNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLF 215
Query: 605 LPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEH 664
+ A + ++ T L P+ E + K + + EEE+EEEEE+E+EE
Sbjct: 216 IQPEDAEE---VVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
Query: 665 EKKKLEDGSLSRPQPEIEPEAAVQE 689
E ++ E+ + E E E +E
Sbjct: 273 EDEEEEEEEEEEEEEEEEEEEEEEE 297
Score = 32.0 bits (71), Expect = 2.3
Identities = 43/184 (23%), Positives = 68/184 (36%), Gaps = 44/184 (23%)
Query: 212 VLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFG----- 266
V H S P G ++ G Y G + LN +I T +G + G
Sbjct: 137 VKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVH 196
Query: 267 -------------GSTRLFILQGPEEDREAESELTVTQLKEL-------------RKQQQ 300
G LFI ED E E+T + ++L KQ+
Sbjct: 197 LLQEAAEGAASEEGEKGLFI---QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG 253
Query: 301 ILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQ 360
IL ++ E+ +EEEE + E + +++E E+ E++ EE E ++
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE-------EEEEEEEEEEEEE---EEEE 303
Query: 361 EREA 364
E EA
Sbjct: 304 EEEA 307
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.4 bits (111), Expect = 5e-05
Identities = 89/428 (20%), Positives = 175/428 (40%), Gaps = 52/428 (12%)
Query: 271 LFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEE------EMDTSERK 324
L + + EE EA+ EL T + + ++ K +G++ E E E E K
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Query: 325 INAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEE 384
+DE+ T EDA + E N L+ Q ER+ + + + R+ E
Sbjct: 1546 TQLEELEDELQAT----EDA-KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Query: 385 LEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGK-KKEAMIQCSLEACRILDTLGL 443
E E +++ L + K L +A + K ++EA+ Q ++ D
Sbjct: 1601 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1660
Query: 444 LRQEAVSR----------KRKAKNWEDEDFYDSDDDTFLDRTGL---IEKKRL-----NR 485
L SR ++KAK+ E + +D +R +EK+ L +
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Query: 486 MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQ-DSLDAFMSEMK 544
+ + ++ E+ +A+L E EL E ++A S + ++ Q + L ++ +
Sbjct: 1721 LSGRNALQDEKRRLEARIAQL---EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
Query: 545 SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTG-AENKAKKL 603
S + + +R++L + ELR + ++G +K + I L+ Q E +A++
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE- 1836
Query: 604 TLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEE 663
K L K +L L++++DE ++ E+ +E+ E+ + +
Sbjct: 1837 ----------------KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
Query: 664 HEKKKLED 671
K++LE+
Sbjct: 1881 QLKRQLEE 1888
Score = 40.0 bits (92), Expect = 0.009
Identities = 87/420 (20%), Positives = 163/420 (38%), Gaps = 54/420 (12%)
Query: 278 EEDREAESELTVTQLKEL-RKQQQILLEKKMLGEDSDEEEEM--DTSERKINAGSQDDEM 334
E ++AE+EL KEL +K Q+ EK +L E E E+ + E ++ ++ E+
Sbjct: 866 ERQQKAENEL-----KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 335 GCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGH 394
E+ E LE +++R + KK Q D E + E E Q
Sbjct: 921 -----------EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 395 STWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKR- 453
+ + LV + ++ KE + LE RI D L +E K
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL---LEE-RISDLTTNLAEEEEKAKNL 1025
Query: 454 -KAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERE 512
K KN + + + + E ++L R K G + E L A++ + + +
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKR-KLEGDASDFHEQIADLQAQIAELKMQ 1084
Query: 513 LSEISERLKASSQVLSESPSQDS--------LDAFMSEMKSGSTLDGVSRKKLHLRTFEL 564
L++ E L+A+ L + +Q + L+ +S+++ + +R K + +L
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1144
Query: 565 RKEQQRLKGLI-------------KIVKPAEIPELKKT-ETQTTGAENKAKKLTLPLFGA 610
+E + LK + + + E+ LKK + +T E + +++
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR------ 1198
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
K + T + + + L ++ E E + K++ EH+KKKLE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Score = 37.0 bits (84), Expect = 0.072
Identities = 53/231 (22%), Positives = 99/231 (42%), Gaps = 36/231 (15%)
Query: 557 LHLRTFELRKEQQRLKGLIKIVKP-----AEIPELKKTETQTTGAENKAKKLTLPLFGAM 611
L LR ++ + ++K L+++ + A+ EL+KT+ + AEN+ K+L
Sbjct: 827 LKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLT 886
Query: 612 KGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDE-PEVEEEEE---EEEEEEKEKEEHEKK 667
+ + + + +L + E+ L K E E+ E E EEEE+ ++ + E+K
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
Query: 668 KLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENM-------SQLSEEEQNKDY 720
K+ L + E EAA Q+++ K + + + ++LS+E + +
Sbjct: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1006
Query: 721 QDCSKTTSLCAGPSASKN--------------------EYEKSRGELKKKK 751
+ TT+L +KN + EKSR EL+K K
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1057
Score = 36.6 bits (83), Expect = 0.094
Identities = 94/444 (21%), Positives = 181/444 (40%), Gaps = 78/444 (17%)
Query: 280 DREAESELTVTQLKELRKQQQILLEKK-----------------------------MLGE 310
D + + +L K+ RK Q+L E+K L E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 311 DSDEEEEMDTSERKINAGSQD-----DEMGCT---WGMGEDAVEDDAEENPIVLEFQQER 362
+ +EE++ + + + A +D D++G + A+E EE LE + E
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE-ELED 1553
Query: 363 EAFYIKDPK-------KALQGFFDREGEELEYEFDEQGH--STWLCRVRLPVDDSTGKQL 413
E +D K +AL+G F+R+ + + + +E+ L ++D ++
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
Query: 414 VAEAIHSGKKKEAMIQ-CSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFL 472
+A A + KK E ++ L+A D+ R+EA+ + RK + + +DF +D
Sbjct: 1614 LAAA--AKKKLEGDLKDLELQA----DSAIKGREEAIKQLRKLQA-QMKDFQRELEDARA 1666
Query: 473 DRTGLIEKKRLNRMKKAGKIDEKPETFESLVA---KLNDAERELSEISERLKASSQVLSE 529
R + + N K + + E L A A+ E E++E L +S +
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL--ASSLSGR 1724
Query: 530 SPSQDS---LDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPEL 586
+ QD L+A +++++ + + + + R + ++ ++L + E
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL----ATERSTA 1780
Query: 587 KKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPE 646
+K E+ E + K+L L M+G K K K+ T+ L K +L E +
Sbjct: 1781 QKNESARQQLERQNKELRSKLH-EMEGAVKSKFKS-TIAALEAKIAQL---------EEQ 1829
Query: 647 VEEEEEEEEEEEKEKEEHEKKKLE 670
VE+E E++ K ++ +KK E
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKE 1853
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 640 RMKDEPEVEEEEEEEEEEEKEKEEHEKKKL--------EDGSLSRPQPEIEPE--AAVQE 689
R ++E + +E+E ++ +E ++K E+E K+L E+ +L + Q + E E A +E
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 690 MRPPTDLTHFKETQTHENMSQLSEEEQNKDYQ---DCSKTTSLCAGPSASKNEYEKSRGE 746
MR + + M EEE+++ Q + K E E +R +
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 747 LKKKKTPGPGKL 758
L+ +K K+
Sbjct: 969 LQLEKVTAEAKI 980
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 47.4 bits (111), Expect = 5e-05
Identities = 89/428 (20%), Positives = 175/428 (40%), Gaps = 52/428 (12%)
Query: 271 LFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEE------EMDTSERK 324
L + + EE EA+ EL T + + ++ K +G++ E E E E K
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Query: 325 INAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEE 384
+DE+ T EDA + E N L+ Q ER+ + + + R+ E
Sbjct: 1553 TQLEELEDELQAT----EDA-KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Query: 385 LEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGK-KKEAMIQCSLEACRILDTLGL 443
E E +++ L + K L +A + K ++EA+ Q ++ D
Sbjct: 1608 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1667
Query: 444 LRQEAVSR----------KRKAKNWEDEDFYDSDDDTFLDRTGL---IEKKRL-----NR 485
L SR ++KAK+ E + +D +R +EK+ L +
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Query: 486 MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQ-DSLDAFMSEMK 544
+ + ++ E+ +A+L E EL E ++A S + ++ Q + L ++ +
Sbjct: 1728 LSGRNALQDEKRRLEARIAQL---EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
Query: 545 SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTG-AENKAKKL 603
S + + +R++L + ELR + ++G +K + I L+ Q E +A++
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE- 1843
Query: 604 TLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEE 663
K L K +L L++++DE ++ E+ +E+ E+ + +
Sbjct: 1844 ----------------KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1887
Query: 664 HEKKKLED 671
K++LE+
Sbjct: 1888 QLKRQLEE 1895
Score = 40.0 bits (92), Expect = 0.009
Identities = 87/420 (20%), Positives = 163/420 (38%), Gaps = 54/420 (12%)
Query: 278 EEDREAESELTVTQLKEL-RKQQQILLEKKMLGEDSDEEEEM--DTSERKINAGSQDDEM 334
E ++AE+EL KEL +K Q+ EK +L E E E+ + E ++ ++ E+
Sbjct: 873 ERQQKAENEL-----KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 927
Query: 335 GCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGH 394
E+ E LE +++R + KK Q D E + E E Q
Sbjct: 928 -----------EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 395 STWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKR- 453
+ + LV + ++ KE + LE RI D L +E K
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL---LEE-RISDLTTNLAEEEEKAKNL 1032
Query: 454 -KAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERE 512
K KN + + + + E ++L R K G + E L A++ + + +
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKR-KLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 513 LSEISERLKASSQVLSESPSQDS--------LDAFMSEMKSGSTLDGVSRKKLHLRTFEL 564
L++ E L+A+ L + +Q + L+ +S+++ + +R K + +L
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1151
Query: 565 RKEQQRLKGLI-------------KIVKPAEIPELKKT-ETQTTGAENKAKKLTLPLFGA 610
+E + LK + + + E+ LKK + +T E + +++
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR------ 1205
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
K + T + + + L ++ E E + K++ EH+KKKLE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Score = 37.0 bits (84), Expect = 0.072
Identities = 53/231 (22%), Positives = 99/231 (42%), Gaps = 36/231 (15%)
Query: 557 LHLRTFELRKEQQRLKGLIKIVKP-----AEIPELKKTETQTTGAENKAKKLTLPLFGAM 611
L LR ++ + ++K L+++ + A+ EL+KT+ + AEN+ K+L
Sbjct: 834 LKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLT 893
Query: 612 KGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDE-PEVEEEEE---EEEEEEKEKEEHEKK 667
+ + + + +L + E+ L K E E+ E E EEEE+ ++ + E+K
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 953
Query: 668 KLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENM-------SQLSEEEQNKDY 720
K+ L + E EAA Q+++ K + + + ++LS+E + +
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1013
Query: 721 QDCSKTTSLCAGPSASKN--------------------EYEKSRGELKKKK 751
+ TT+L +KN + EKSR EL+K K
Sbjct: 1014 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1064
Score = 36.6 bits (83), Expect = 0.094
Identities = 94/444 (21%), Positives = 181/444 (40%), Gaps = 78/444 (17%)
Query: 280 DREAESELTVTQLKELRKQQQILLEKK-----------------------------MLGE 310
D + + +L K+ RK Q+L E+K L E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 311 DSDEEEEMDTSERKINAGSQD-----DEMGCT---WGMGEDAVEDDAEENPIVLEFQQER 362
+ +EE++ + + + A +D D++G + A+E EE LE + E
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE-ELED 1560
Query: 363 EAFYIKDPK-------KALQGFFDREGEELEYEFDEQGH--STWLCRVRLPVDDSTGKQL 413
E +D K +AL+G F+R+ + + + +E+ L ++D ++
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 414 VAEAIHSGKKKEAMIQ-CSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFL 472
+A A + KK E ++ L+A D+ R+EA+ + RK + + +DF +D
Sbjct: 1621 LAAA--AKKKLEGDLKDLELQA----DSAIKGREEAIKQLRKLQA-QMKDFQRELEDARA 1673
Query: 473 DRTGLIEKKRLNRMKKAGKIDEKPETFESLVA---KLNDAERELSEISERLKASSQVLSE 529
R + + N K + + E L A A+ E E++E L +S +
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL--ASSLSGR 1731
Query: 530 SPSQDS---LDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPEL 586
+ QD L+A +++++ + + + + R + ++ ++L + E
Sbjct: 1732 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL----ATERSTA 1787
Query: 587 KKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPE 646
+K E+ E + K+L L M+G K K K+ T+ L K +L E +
Sbjct: 1788 QKNESARQQLERQNKELRSKLH-EMEGAVKSKFKS-TIAALEAKIAQL---------EEQ 1836
Query: 647 VEEEEEEEEEEEKEKEEHEKKKLE 670
VE+E E++ K ++ +KK E
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKE 1860
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 640 RMKDEPEVEEEEEEEEEEEKEKEEHEKKKL--------EDGSLSRPQPEIEPE--AAVQE 689
R ++E + +E+E ++ +E ++K E+E K+L E+ +L + Q + E E A +E
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 690 MRPPTDLTHFKETQTHENMSQLSEEEQNKDYQ---DCSKTTSLCAGPSASKNEYEKSRGE 746
MR + + M EEE+++ Q + K E E +R +
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 747 LKKKKTPGPGKL 758
L+ +K K+
Sbjct: 976 LQLEKVTAEAKI 987
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 47.4 bits (111), Expect = 5e-05
Identities = 89/428 (20%), Positives = 175/428 (40%), Gaps = 52/428 (12%)
Query: 271 LFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEE------EMDTSERK 324
L + + EE EA+ EL T + + ++ K +G++ E E E E K
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Query: 325 INAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEE 384
+DE+ T EDA + E N L+ Q ER+ + + + R+ E
Sbjct: 1553 TQLEELEDELQAT----EDA-KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Query: 385 LEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGK-KKEAMIQCSLEACRILDTLGL 443
E E +++ L + K L +A + K ++EA+ Q ++ D
Sbjct: 1608 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1667
Query: 444 LRQEAVSR----------KRKAKNWEDEDFYDSDDDTFLDRTGL---IEKKRL-----NR 485
L SR ++KAK+ E + +D +R +EK+ L +
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Query: 486 MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQ-DSLDAFMSEMK 544
+ + ++ E+ +A+L E EL E ++A S + ++ Q + L ++ +
Sbjct: 1728 LSGRNALQDEKRRLEARIAQL---EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
Query: 545 SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTG-AENKAKKL 603
S + + +R++L + ELR + ++G +K + I L+ Q E +A++
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE- 1843
Query: 604 TLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEE 663
K L K +L L++++DE ++ E+ +E+ E+ + +
Sbjct: 1844 ----------------KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1887
Query: 664 HEKKKLED 671
K++LE+
Sbjct: 1888 QLKRQLEE 1895
Score = 40.0 bits (92), Expect = 0.009
Identities = 87/420 (20%), Positives = 163/420 (38%), Gaps = 54/420 (12%)
Query: 278 EEDREAESELTVTQLKEL-RKQQQILLEKKMLGEDSDEEEEM--DTSERKINAGSQDDEM 334
E ++AE+EL KEL +K Q+ EK +L E E E+ + E ++ ++ E+
Sbjct: 873 ERQQKAENEL-----KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 927
Query: 335 GCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGH 394
E+ E LE +++R + KK Q D E + E E Q
Sbjct: 928 -----------EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 395 STWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKR- 453
+ + LV + ++ KE + LE RI D L +E K
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL---LEE-RISDLTTNLAEEEEKAKNL 1032
Query: 454 -KAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERE 512
K KN + + + + E ++L R K G + E L A++ + + +
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKR-KLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 513 LSEISERLKASSQVLSESPSQDS--------LDAFMSEMKSGSTLDGVSRKKLHLRTFEL 564
L++ E L+A+ L + +Q + L+ +S+++ + +R K + +L
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1151
Query: 565 RKEQQRLKGLI-------------KIVKPAEIPELKKT-ETQTTGAENKAKKLTLPLFGA 610
+E + LK + + + E+ LKK + +T E + +++
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR------ 1205
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
K + T + + + L ++ E E + K++ EH+KKKLE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Score = 37.0 bits (84), Expect = 0.072
Identities = 53/231 (22%), Positives = 99/231 (42%), Gaps = 36/231 (15%)
Query: 557 LHLRTFELRKEQQRLKGLIKIVKP-----AEIPELKKTETQTTGAENKAKKLTLPLFGAM 611
L LR ++ + ++K L+++ + A+ EL+KT+ + AEN+ K+L
Sbjct: 834 LKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLT 893
Query: 612 KGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDE-PEVEEEEE---EEEEEEKEKEEHEKK 667
+ + + + +L + E+ L K E E+ E E EEEE+ ++ + E+K
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 953
Query: 668 KLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENM-------SQLSEEEQNKDY 720
K+ L + E EAA Q+++ K + + + ++LS+E + +
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1013
Query: 721 QDCSKTTSLCAGPSASKN--------------------EYEKSRGELKKKK 751
+ TT+L +KN + EKSR EL+K K
Sbjct: 1014 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1064
Score = 36.6 bits (83), Expect = 0.094
Identities = 94/444 (21%), Positives = 181/444 (40%), Gaps = 78/444 (17%)
Query: 280 DREAESELTVTQLKELRKQQQILLEKK-----------------------------MLGE 310
D + + +L K+ RK Q+L E+K L E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 311 DSDEEEEMDTSERKINAGSQD-----DEMGCT---WGMGEDAVEDDAEENPIVLEFQQER 362
+ +EE++ + + + A +D D++G + A+E EE LE + E
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE-ELED 1560
Query: 363 EAFYIKDPK-------KALQGFFDREGEELEYEFDEQGH--STWLCRVRLPVDDSTGKQL 413
E +D K +AL+G F+R+ + + + +E+ L ++D ++
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 414 VAEAIHSGKKKEAMIQ-CSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFL 472
+A A + KK E ++ L+A D+ R+EA+ + RK + + +DF +D
Sbjct: 1621 LAAA--AKKKLEGDLKDLELQA----DSAIKGREEAIKQLRKLQA-QMKDFQRELEDARA 1673
Query: 473 DRTGLIEKKRLNRMKKAGKIDEKPETFESLVA---KLNDAERELSEISERLKASSQVLSE 529
R + + N K + + E L A A+ E E++E L +S +
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL--ASSLSGR 1731
Query: 530 SPSQDS---LDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPEL 586
+ QD L+A +++++ + + + + R + ++ ++L + E
Sbjct: 1732 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL----ATERSTA 1787
Query: 587 KKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPE 646
+K E+ E + K+L L M+G K K K+ T+ L K +L E +
Sbjct: 1788 QKNESARQQLERQNKELRSKLH-EMEGAVKSKFKS-TIAALEAKIAQL---------EEQ 1836
Query: 647 VEEEEEEEEEEEKEKEEHEKKKLE 670
VE+E E++ K ++ +KK E
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKE 1860
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 640 RMKDEPEVEEEEEEEEEEEKEKEEHEKKKL--------EDGSLSRPQPEIEPE--AAVQE 689
R ++E + +E+E ++ +E ++K E+E K+L E+ +L + Q + E E A +E
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 690 MRPPTDLTHFKETQTHENMSQLSEEEQNKDYQ---DCSKTTSLCAGPSASKNEYEKSRGE 746
MR + + M EEE+++ Q + K E E +R +
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 747 LKKKKTPGPGKL 758
L+ +K K+
Sbjct: 976 LQLEKVTAEAKI 987
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 47.4 bits (111), Expect = 5e-05
Identities = 89/428 (20%), Positives = 175/428 (40%), Gaps = 52/428 (12%)
Query: 271 LFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEE------EMDTSERK 324
L + + EE EA+ EL T + + ++ K +G++ E E E E K
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Query: 325 INAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEE 384
+DE+ T EDA + E N L+ Q ER+ + + + R+ E
Sbjct: 1546 TQLEELEDELQAT----EDA-KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Query: 385 LEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGK-KKEAMIQCSLEACRILDTLGL 443
E E +++ L + K L +A + K ++EA+ Q ++ D
Sbjct: 1601 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1660
Query: 444 LRQEAVSR----------KRKAKNWEDEDFYDSDDDTFLDRTGL---IEKKRL-----NR 485
L SR ++KAK+ E + +D +R +EK+ L +
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Query: 486 MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQ-DSLDAFMSEMK 544
+ + ++ E+ +A+L E EL E ++A S + ++ Q + L ++ +
Sbjct: 1721 LSGRNALQDEKRRLEARIAQL---EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
Query: 545 SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTG-AENKAKKL 603
S + + +R++L + ELR + ++G +K + I L+ Q E +A++
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE- 1836
Query: 604 TLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEE 663
K L K +L L++++DE ++ E+ +E+ E+ + +
Sbjct: 1837 ----------------KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
Query: 664 HEKKKLED 671
K++LE+
Sbjct: 1881 QLKRQLEE 1888
Score = 40.0 bits (92), Expect = 0.009
Identities = 87/420 (20%), Positives = 163/420 (38%), Gaps = 54/420 (12%)
Query: 278 EEDREAESELTVTQLKEL-RKQQQILLEKKMLGEDSDEEEEM--DTSERKINAGSQDDEM 334
E ++AE+EL KEL +K Q+ EK +L E E E+ + E ++ ++ E+
Sbjct: 866 ERQQKAENEL-----KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 335 GCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGH 394
E+ E LE +++R + KK Q D E + E E Q
Sbjct: 921 -----------EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 395 STWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKR- 453
+ + LV + ++ KE + LE RI D L +E K
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL---LEE-RISDLTTNLAEEEEKAKNL 1025
Query: 454 -KAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERE 512
K KN + + + + E ++L R K G + E L A++ + + +
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKR-KLEGDASDFHEQIADLQAQIAELKMQ 1084
Query: 513 LSEISERLKASSQVLSESPSQDS--------LDAFMSEMKSGSTLDGVSRKKLHLRTFEL 564
L++ E L+A+ L + +Q + L+ +S+++ + +R K + +L
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1144
Query: 565 RKEQQRLKGLI-------------KIVKPAEIPELKKT-ETQTTGAENKAKKLTLPLFGA 610
+E + LK + + + E+ LKK + +T E + +++
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR------ 1198
Query: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670
K + T + + + L ++ E E + K++ EH+KKKLE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Score = 37.0 bits (84), Expect = 0.072
Identities = 53/231 (22%), Positives = 99/231 (42%), Gaps = 36/231 (15%)
Query: 557 LHLRTFELRKEQQRLKGLIKIVKP-----AEIPELKKTETQTTGAENKAKKLTLPLFGAM 611
L LR ++ + ++K L+++ + A+ EL+KT+ + AEN+ K+L
Sbjct: 827 LKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLT 886
Query: 612 KGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDE-PEVEEEEE---EEEEEEKEKEEHEKK 667
+ + + + +L + E+ L K E E+ E E EEEE+ ++ + E+K
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
Query: 668 KLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENM-------SQLSEEEQNKDY 720
K+ L + E EAA Q+++ K + + + ++LS+E + +
Sbjct: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1006
Query: 721 QDCSKTTSLCAGPSASKN--------------------EYEKSRGELKKKK 751
+ TT+L +KN + EKSR EL+K K
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1057
Score = 36.6 bits (83), Expect = 0.094
Identities = 94/444 (21%), Positives = 181/444 (40%), Gaps = 78/444 (17%)
Query: 280 DREAESELTVTQLKELRKQQQILLEKK-----------------------------MLGE 310
D + + +L K+ RK Q+L E+K L E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 311 DSDEEEEMDTSERKINAGSQD-----DEMGCT---WGMGEDAVEDDAEENPIVLEFQQER 362
+ +EE++ + + + A +D D++G + A+E EE LE + E
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE-ELED 1553
Query: 363 EAFYIKDPK-------KALQGFFDREGEELEYEFDEQGH--STWLCRVRLPVDDSTGKQL 413
E +D K +AL+G F+R+ + + + +E+ L ++D ++
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
Query: 414 VAEAIHSGKKKEAMIQ-CSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFL 472
+A A + KK E ++ L+A D+ R+EA+ + RK + + +DF +D
Sbjct: 1614 LAAA--AKKKLEGDLKDLELQA----DSAIKGREEAIKQLRKLQA-QMKDFQRELEDARA 1666
Query: 473 DRTGLIEKKRLNRMKKAGKIDEKPETFESLVA---KLNDAERELSEISERLKASSQVLSE 529
R + + N K + + E L A A+ E E++E L +S +
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL--ASSLSGR 1724
Query: 530 SPSQDS---LDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPEL 586
+ QD L+A +++++ + + + + R + ++ ++L + E
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL----ATERSTA 1780
Query: 587 KKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPE 646
+K E+ E + K+L L M+G K K K+ T+ L K +L E +
Sbjct: 1781 QKNESARQQLERQNKELRSKLH-EMEGAVKSKFKS-TIAALEAKIAQL---------EEQ 1829
Query: 647 VEEEEEEEEEEEKEKEEHEKKKLE 670
VE+E E++ K ++ +KK E
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKE 1853
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 640 RMKDEPEVEEEEEEEEEEEKEKEEHEKKKL--------EDGSLSRPQPEIEPE--AAVQE 689
R ++E + +E+E ++ +E ++K E+E K+L E+ +L + Q + E E A +E
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 690 MRPPTDLTHFKETQTHENMSQLSEEEQNKDYQ---DCSKTTSLCAGPSASKNEYEKSRGE 746
MR + + M EEE+++ Q + K E E +R +
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 747 LKKKKTPGPGKL 758
L+ +K K+
Sbjct: 969 LQLEKVTAEAKI 980
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 46.6 bits (109), Expect = 9e-05
Identities = 58/254 (22%), Positives = 104/254 (40%), Gaps = 26/254 (10%)
Query: 479 EKKRLNRMKK-----AGK--IDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESP 531
+K R + KK AGK ++++ E ++ + ERE E ++L +++
Sbjct: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQ 208
Query: 532 SQDSL--DAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKT 589
+ L DAF + +DG + EL+ + + AE L
Sbjct: 209 QEQELAADAFK---ELDDDMDGT------VSVTELQTHPELDTDGDGALSEAEAQALLSG 259
Query: 590 ETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEE 649
+TQT + ++ A++ K++ + P P+L P
Sbjct: 260 DTQTDATSFYDR-----VWAAIR--DKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPT 312
Query: 650 EEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMS 709
EEEEEEEEE+E+E E+++ ED + QP+ A +M P + T E +
Sbjct: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN 372
Query: 710 QLSEEEQN-KDYQD 722
+ E E++ KD ++
Sbjct: 373 KFEEAERSLKDMEE 386
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,976,472
Number of Sequences: 37866
Number of extensions: 2217907
Number of successful extensions: 40407
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 610
Number of HSP's successfully gapped in prelim test: 950
Number of HSP's that attempted gapping in prelim test: 18222
Number of HSP's gapped (non-prelim): 11041
length of query: 796
length of database: 18,247,518
effective HSP length: 110
effective length of query: 686
effective length of database: 14,082,258
effective search space: 9660428988
effective search space used: 9660428988
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.