Search of human proteins with 15559207

Search of human proteins with 15559207

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15559207 elastase 2A preproprotein [Homo sapiens]
         (269 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15559207 elastase 2A preproprotein [Homo sapiens]                  565   e-161
gi|58331211 elastase 2B preproprotein [Homo sapiens]                  503   e-143
gi|62526043 chymotrypsin C preproprotein [Homo sapiens]               345   2e-95
gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]       317   7e-87
gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]     312   2e-85
gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa...   295   3e-80
gi|4503137 chymotrypsin-like [Homo sapiens]                           202   2e-52
gi|118498341 chymotrypsin B1 [Homo sapiens]                           179   2e-45
gi|33695155 hepsin [Homo sapiens]                                     178   4e-45
gi|4504481 hepsin [Homo sapiens]                                      178   4e-45
gi|118498350 chymotrypsin B2 [Homo sapiens]                           178   5e-45
gi|4505881 plasminogen [Homo sapiens]                                 171   8e-43
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  169   2e-42
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            169   3e-42
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          167   7e-42
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   166   2e-41
gi|110815798 ovochymase 1 [Homo sapiens]                              166   3e-41
gi|148613878 acrosin precursor [Homo sapiens]                         164   6e-41
gi|117956391 protease, serine, 33 [Homo sapiens]                      163   1e-40
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   162   4e-40
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   162   4e-40
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        161   5e-40
gi|58218970 protease, serine, 36 [Homo sapiens]                       160   1e-39
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   159   2e-39
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   159   2e-39
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]               159   3e-39
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      157   7e-39
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             155   3e-38
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           154   6e-38
gi|4506153 prostasin preproprotein [Homo sapiens]                     153   1e-37

>gi|15559207 elastase 2A preproprotein [Homo sapiens]
          Length = 269

 Score =  565 bits (1456), Expect = e-161
 Identities = 269/269 (100%), Positives = 269/269 (100%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60
           MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG
Sbjct: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60

Query: 61  SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN 120
           SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN
Sbjct: 61  SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN 120

Query: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV 180
           DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV
Sbjct: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV 180

Query: 181 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR 240
           VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR
Sbjct: 181 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR 240

Query: 241 LGCNYYHKPSVFTRVSNYIDWINSVIANN 269
           LGCNYYHKPSVFTRVSNYIDWINSVIANN
Sbjct: 241 LGCNYYHKPSVFTRVSNYIDWINSVIANN 269


>gi|58331211 elastase 2B preproprotein [Homo sapiens]
          Length = 269

 Score =  503 bits (1294), Expect = e-143
 Identities = 238/269 (88%), Positives = 254/269 (94%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60
           MIRTLLLSTLVAGALSCG  TY P ++R++GGEEARPNSWPWQVSLQYSSNG+WYHTCGG
Sbjct: 1   MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60

Query: 61  SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN 120
           SLIANSWVLTAAHCISSS  YRV LG+HNLYVAESGSLAVSVSKIVVHKDWNS+Q+SKGN
Sbjct: 61  SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120

Query: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV 180
           DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA+PD L+QGRLLV
Sbjct: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV 180

Query: 181 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR 240
           VDYATCSSS WWGS+VKT+MICAGGDGVI +CNGDSGGPLNCQASDGRW+VHGI S  S 
Sbjct: 181 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV 240

Query: 241 LGCNYYHKPSVFTRVSNYIDWINSVIANN 269
           LGCNYY+KPS+FTRVSNY DWINSVIANN
Sbjct: 241 LGCNYYYKPSIFTRVSNYNDWINSVIANN 269


>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
          Length = 268

 Score =  345 bits (886), Expect = 2e-95
 Identities = 168/265 (63%), Positives = 204/265 (76%), Gaps = 4/265 (1%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVT-RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCG 59
           M+   +L+ L+A A SCG P++PP ++ RVVGGE+ARP+SWPWQ+SLQY  N  W HTCG
Sbjct: 1   MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60

Query: 60  GSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVA-ESGSLAVSVSKIVVHKDWNSNQISK 118
           G+LIA+++VLTAAHCIS++RTYRV +G++NL V  E GSL V V  I VHK WN+  +  
Sbjct: 61  GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLR- 119

Query: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRL 178
            NDIAL+KLA  V L+D IQ+ACLP   ++LP +YPCYVTGWGRL TNG + D LQQG  
Sbjct: 120 -NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178

Query: 179 LVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFG 238
            VVD+ATCS   WWG  VK +M+CAGGDGVIS+CNGDSGGPLNCQ  +G W+V GIVSFG
Sbjct: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG 238

Query: 239 SRLGCNYYHKPSVFTRVSNYIDWIN 263
           SR GCN   KP V+TRVS YIDWIN
Sbjct: 239 SRRGCNTRKKPVVYTRVSAYIDWIN 263


>gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]
          Length = 270

 Score =  317 bits (812), Expect = 7e-87
 Identities = 157/271 (57%), Positives = 188/271 (69%), Gaps = 4/271 (1%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60
           M+R L    LVA A   G P+  P  +RVV GE+A P SWPWQVSLQY  +G +YHTCGG
Sbjct: 2   MLRLLSSLLLVAVASGYGPPSSRPS-SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60

Query: 61  SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSK--IVVHKDWNSNQISK 118
           SLIA  WV+TA HCISSSRTY+V LG ++  V E     + ++   + VH  WN + ++ 
Sbjct: 61  SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120

Query: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRL 178
           GNDIAL+KL+    L D +QLA LPPAG ILPN  PCY+TGWGRL TNG +PD LQ+  L
Sbjct: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180

Query: 179 LVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFG 238
            VVDY  CS   WWGSSVK +M+CAGGD + S CNGDSGGPLNC   DG WQVHG+ SF 
Sbjct: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFV 239

Query: 239 SRLGCNYYHKPSVFTRVSNYIDWINSVIANN 269
           S  GCN   KP+VFTRVS +IDWI   IA++
Sbjct: 240 SAFGCNTRRKPTVFTRVSAFIDWIEETIASH 270


>gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]
          Length = 270

 Score =  312 bits (800), Expect = 2e-85
 Identities = 155/271 (57%), Positives = 187/271 (69%), Gaps = 4/271 (1%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60
           M+R L    LVA A   G P+     +RVV GE+A P SWPWQVSLQY  +G +YHTCGG
Sbjct: 2   MLRLLSSLLLVAVASGYGPPSSHSS-SRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60

Query: 61  SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVS--KIVVHKDWNSNQISK 118
           SLIA  WV+TA HCIS   TY+V LG +NL V E     + ++  ++ VH  WN + ++ 
Sbjct: 61  SLIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVAC 120

Query: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRL 178
           GNDIAL+KL+    L D +QLA LPPAG ILPN  PCY+TGWGRL TNG +PD LQQ RL
Sbjct: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQARL 180

Query: 179 LVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFG 238
            VVDY  CS   WWGS+VK +M+CAGG  + S CNGDSGGPLNC   DG WQVHG+ SF 
Sbjct: 181 PVVDYKHCSRWNWWGSTVKKTMVCAGG-YIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFV 239

Query: 239 SRLGCNYYHKPSVFTRVSNYIDWINSVIANN 269
           S  GCN+  KP+VFTRVS +IDWI   IA++
Sbjct: 240 SAFGCNFIWKPTVFTRVSAFIDWIEETIASH 270


>gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
           sapiens]
          Length = 258

 Score =  295 bits (755), Expect = 3e-80
 Identities = 142/247 (57%), Positives = 174/247 (70%), Gaps = 1/247 (0%)

Query: 23  PPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYR 82
           P    RVVGG EA  NSWP Q+SLQY S G  YHTCGG+LI  +WV+TAAHC+   +T+R
Sbjct: 13  PETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFR 72

Query: 83  VGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACL 142
           V  G HNL   +     VSV KIVVH  WNS+ ++ G DIALL+LA  V+L   +QL  L
Sbjct: 73  VVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVL 132

Query: 143 PPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMIC 202
           P  G IL NN PCY+TGWG+ +TNG +   LQQ  L  VDYA CSSS++WGS+VK +M+C
Sbjct: 133 PQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVC 192

Query: 203 AGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWI 262
           AGGDGV S C GDSGGPL+C   +G++ VHG+ SF S  GCN   KP+VFT+VS YI WI
Sbjct: 193 AGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWI 251

Query: 263 NSVIANN 269
           N+VIA+N
Sbjct: 252 NNVIASN 258


>gi|4503137 chymotrypsin-like [Homo sapiens]
          Length = 264

 Score =  202 bits (514), Expect = 2e-52
 Identities = 124/274 (45%), Positives = 159/274 (58%), Gaps = 16/274 (5%)

Query: 1   MIRTLLLSTLVAGAL-SCGDPTYPPYVT---RVVGGEEARPNSWPWQVSLQYSSNGKWYH 56
           ++ +L LS ++ G+   CG P   P ++   R+V GE A   SWPWQVSLQ SS    +H
Sbjct: 2   LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---FH 58

Query: 57  TCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQI 116
            CGGSLI+ SWV+TAAHC  S   + V LG ++          +SVS+ + H  WNS  +
Sbjct: 59  FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM 118

Query: 117 SKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAV-PDVLQQ 175
           +  ND+ LLKLA+P   T +I   CL  +   L     C  TGWGRL   G V P  LQQ
Sbjct: 119 N--NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ 176

Query: 176 GRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIV 235
             L +V    C    +WGSS+  SMICAGG G  SSC GDSGGPL CQ  +  W + GIV
Sbjct: 177 VALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGIV 232

Query: 236 SFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN 269
           S+G++  CN    P+V+TRVS +  WIN VIA N
Sbjct: 233 SWGTK-NCN-VRAPAVYTRVSKFSTWINQVIAYN 264


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  179 bits (455), Expect = 2e-45
 Identities = 112/266 (42%), Positives = 145/266 (54%), Gaps = 18/266 (6%)

Query: 9   TLVAGALSCGDPTYPPYVT---RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIAN 65
           +LV  A  CG P   P ++   R+V GE+A P SWPWQVSLQ  +    +H CGGSLI+ 
Sbjct: 11  SLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---FHFCGGSLISE 67

Query: 66  SWVLTAAHCISSSRTYRVGL-GRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIAL 124
            WV+TAAHC    RT  V + G  +    E     + ++K  V K+   + ++  NDI L
Sbjct: 68  DWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKIAK--VFKNPKFSILTVNNDITL 123

Query: 125 LKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTN-GAVPDVLQQGRLLVVDY 183
           LKLA P   +  +   CLP A    P    C  TGWG+ + N    PD LQQ  L ++  
Sbjct: 124 LKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSN 183

Query: 184 ATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGC 243
           A C  S  WG  +   MICAG  GV SSC GDSGGPL CQ  DG W + GIVS+GS   C
Sbjct: 184 AECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIVSWGSDT-C 238

Query: 244 NYYHKPSVFTRVSNYIDWINSVIANN 269
           +    P V+ RV+  I W+  ++A N
Sbjct: 239 S-TSSPGVYARVTKLIPWVQKILAAN 263


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  178 bits (452), Expect = 4e-45
 Identities = 106/269 (39%), Positives = 145/269 (53%), Gaps = 22/269 (8%)

Query: 10  LVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVL 69
           L A    CG    P  V R+VGG +     WPWQVSL+Y       H CGGSL++  WVL
Sbjct: 146 LAAICQDCGRRKLP--VDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVL 199

Query: 70  TAAHCISSSRT----YRVGLGRHNLYVAESGSLAVSVSKIVVHKDW----NSNQISKGND 121
           TAAHC          +RV  G   +  A    L + V  +V H  +    + N     ND
Sbjct: 200 TAAHCFPERNRVLSRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSND 257

Query: 122 IALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVV 181
           IAL+ L++P+ LT+ IQ  CLP AG  L +   C VTGWG  Q  G    VLQ+ R+ ++
Sbjct: 258 IALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPII 317

Query: 182 DYATCSSSAWWGSSVKTSMICAG-GDGVISSCNGDSGGPLNCQAS---DGRWQVHGIVSF 237
               C+ + ++G+ +K  M CAG  +G I +C GDSGGP  C+ S     RW++ GIVS+
Sbjct: 318 SNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW 377

Query: 238 GSRLGCNYYHKPSVFTRVSNYIDWINSVI 266
           G+  GC    KP V+T+VS++ +WI   I
Sbjct: 378 GT--GCALAQKPGVYTKVSDFREWIFQAI 404


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  178 bits (452), Expect = 4e-45
 Identities = 106/269 (39%), Positives = 145/269 (53%), Gaps = 22/269 (8%)

Query: 10  LVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVL 69
           L A    CG    P  V R+VGG +     WPWQVSL+Y       H CGGSL++  WVL
Sbjct: 146 LAAICQDCGRRKLP--VDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVL 199

Query: 70  TAAHCISSSRT----YRVGLGRHNLYVAESGSLAVSVSKIVVHKDW----NSNQISKGND 121
           TAAHC          +RV  G   +  A    L + V  +V H  +    + N     ND
Sbjct: 200 TAAHCFPERNRVLSRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSND 257

Query: 122 IALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVV 181
           IAL+ L++P+ LT+ IQ  CLP AG  L +   C VTGWG  Q  G    VLQ+ R+ ++
Sbjct: 258 IALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPII 317

Query: 182 DYATCSSSAWWGSSVKTSMICAG-GDGVISSCNGDSGGPLNCQAS---DGRWQVHGIVSF 237
               C+ + ++G+ +K  M CAG  +G I +C GDSGGP  C+ S     RW++ GIVS+
Sbjct: 318 SNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW 377

Query: 238 GSRLGCNYYHKPSVFTRVSNYIDWINSVI 266
           G+  GC    KP V+T+VS++ +WI   I
Sbjct: 378 GT--GCALAQKPGVYTKVSDFREWIFQAI 404


>gi|118498350 chymotrypsin B2 [Homo sapiens]
          Length = 263

 Score =  178 bits (451), Expect = 5e-45
 Identities = 111/265 (41%), Positives = 145/265 (54%), Gaps = 18/265 (6%)

Query: 10  LVAGALSCGDPTYPPYVT---RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANS 66
           L+     CG P   P ++   R+V GE+A P SWPWQVSLQ  +    +H CGGSLI+  
Sbjct: 12  LLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---FHFCGGSLISED 68

Query: 67  WVLTAAHCISSSRTYRVGL-GRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALL 125
           WV+TAAHC    RT  V + G  +    E     + ++K  V K+   + ++  NDI LL
Sbjct: 69  WVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKIAK--VFKNPKFSILTVNNDITLL 124

Query: 126 KLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTN-GAVPDVLQQGRLLVVDYA 184
           KLA P   +  +   CLP A    P    C  TGWG+ + N    PD LQQ  L ++  A
Sbjct: 125 KLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNA 184

Query: 185 TCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCN 244
            C  S  WG  +   MICAG  GV SSC GDSGGPL CQ  DG W + GIVS+GSR  C+
Sbjct: 185 ECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIVSWGSRT-CS 239

Query: 245 YYHKPSVFTRVSNYIDWINSVIANN 269
               P+V+ RV+  I W+  ++A N
Sbjct: 240 -TTTPAVYARVAKLIPWVQKILAAN 263


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  171 bits (432), Expect = 8e-43
 Identities = 104/265 (39%), Positives = 147/265 (55%), Gaps = 23/265 (8%)

Query: 12  AGALSCGDPTYPPYVT--RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVL 69
           A +  CG P   P     RVVGG  A P+SWPWQVSL+        H CGG+LI+  WVL
Sbjct: 562 APSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVL 618

Query: 70  TAAHCISSS---RTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLK 126
           TAAHC+  S    +Y+V LG H     E     + VS++ +             DIALLK
Sbjct: 619 TAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT--------RKDIALLK 670

Query: 127 LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQ-TNGAVPDVLQQGRLLVVDYAT 185
           L++P  +TDK+  ACLP    ++ +   C++TGWG  Q T GA   +L++ +L V++   
Sbjct: 671 LSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGA--GLLKEAQLPVIENKV 728

Query: 186 CSSSAWWGSSVKTSMICAGG-DGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCN 244
           C+   +    V+++ +CAG   G   SC GDSGGPL C   D ++ + G+ S+G  LGC 
Sbjct: 729 CNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKD-KYILQGVTSWG--LGCA 785

Query: 245 YYHKPSVFTRVSNYIDWINSVIANN 269
             +KP V+ RVS ++ WI  V+ NN
Sbjct: 786 RPNKPGVYVRVSRFVTWIEGVMRNN 810


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  169 bits (429), Expect = 2e-42
 Identities = 105/281 (37%), Positives = 152/281 (54%), Gaps = 25/281 (8%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRV--VGGEEARPNSWPWQVSLQYSSNGKWYHTC 58
           M+  LLL+  V  + +   P     + RV  VGG+EA  + WPWQVSL+      W H C
Sbjct: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDR-YWMHFC 59

Query: 59  GGSLIANSWVLTAAHCISSS----RTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSN 114
           GGSLI   WVLTAAHC+          RV L   +LY  +     + VS+I+VH  + + 
Sbjct: 60  GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYTA 116

Query: 115 QISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD--V 172
           QI  G DIALL+L  PV+++  +    LPPA    P   PC+VTGWG +  +  +P    
Sbjct: 117 QI--GADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174

Query: 173 LQQGRLLVVDYATCSSSAWWGS-------SVKTSMICAGGDGVISSCNGDSGGPLNCQAS 225
           L+Q ++ +++   C +    G+        V+  M+CAG      SC GDSGGPL C+  
Sbjct: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV- 232

Query: 226 DGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVI 266
           +G W   G+VS+G   GC   ++P ++TRV+ Y+DWI+  +
Sbjct: 233 NGTWLQAGVVSWGE--GCAQPNRPGIYTRVTYYLDWIHHYV 271


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  169 bits (427), Expect = 3e-42
 Identities = 105/281 (37%), Positives = 152/281 (54%), Gaps = 25/281 (8%)

Query: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRV--VGGEEARPNSWPWQVSLQYSSNGKWYHTC 58
           M+  LLL+  V  + +   P     + RV  VGG+EA  + WPWQVSL+      W H C
Sbjct: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGP-YWMHFC 59

Query: 59  GGSLIANSWVLTAAHCISSS----RTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSN 114
           GGSLI   WVLTAAHC+          RV L   +LY  +     + VS+I+VH  + + 
Sbjct: 60  GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYTA 116

Query: 115 QISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD--V 172
           QI  G DIALL+L  PV+++  +    LPPA    P   PC+VTGWG +  +  +P    
Sbjct: 117 QI--GADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174

Query: 173 LQQGRLLVVDYATCSSSAWWGS-------SVKTSMICAGGDGVISSCNGDSGGPLNCQAS 225
           L+Q ++ +++   C +    G+        V+  M+CAG      SC GDSGGPL C+  
Sbjct: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV- 232

Query: 226 DGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVI 266
           +G W   G+VS+G   GC   ++P ++TRV+ Y+DWI+  +
Sbjct: 233 NGTWLQAGVVSWGE--GCAQPNRPGIYTRVTYYLDWIHHYV 271


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  167 bits (424), Expect = 7e-42
 Identities = 95/242 (39%), Positives = 136/242 (56%), Gaps = 22/242 (9%)

Query: 28  RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYRVGLGR 87
           R++GG EA   SWPWQVSL+ ++     H CGGSLI N W+LTAAHC  S+   R     
Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNA----HHCGGSLINNMWILTAAHCFRSNSNPRD---- 237

Query: 88  HNLYVAESG------SLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLAC 141
              ++A SG       L + V  I++H ++ S   +  NDIAL++L N V+ T  I   C
Sbjct: 238 ---WIATSGISTTFPKLRMRVRNILIHNNYKS--ATHENDIALVRLENSVTFTKDIHSVC 292

Query: 142 LPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMI 201
           LP A   +P     YVTGWG  +  G     L+QG++ ++    C++   +  ++ + M+
Sbjct: 293 LPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGML 352

Query: 202 CAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYID 260
           CAG   G + +C GDSGGPL  + S   W + GIVS+G +  C    KP V+TRV+ Y+D
Sbjct: 353 CAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQ--CGLPDKPGVYTRVTAYLD 410

Query: 261 WI 262
           WI
Sbjct: 411 WI 412


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  166 bits (421), Expect = 2e-41
 Identities = 93/246 (37%), Positives = 139/246 (56%), Gaps = 20/246 (8%)

Query: 25  YVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCI-----SSSR 79
           Y +R+VGG  +  + WPWQ SLQ+      YH CGGS+I   W++TAAHC+       S 
Sbjct: 213 YSSRIVGGNMSLLSQWPWQASLQFQG----YHLCGGSVITPLWIITAAHCVYDLYLPKSW 268

Query: 80  TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQL 139
           T +VGL    + + ++ + +  V KIV H  +   ++  GNDIAL+KLA P++  + IQ 
Sbjct: 269 TIQVGL----VSLLDNPAPSHLVEKIVYHSKYKPKRL--GNDIALMKLAGPLTFNEMIQP 322

Query: 140 ACLPPAGTILPNNYPCYVTGWGRLQTN-GAVPDVLQQGRLLVVDYATCSSSAWWGSSVKT 198
            CLP +    P+   C+ +GWG  +   G    VL    + ++    C+    +G  +  
Sbjct: 323 VCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISP 382

Query: 199 SMICAGG-DGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSN 257
           SM+CAG   G + SC GDSGGPL CQ     W++ G  SFG  +GC   +KP V+TRV++
Sbjct: 383 SMLCAGYLTGGVDSCQGDSGGPLVCQ-ERRLWKLVGATSFG--IGCAEVNKPGVYTRVTS 439

Query: 258 YIDWIN 263
           ++DWI+
Sbjct: 440 FLDWIH 445


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  166 bits (419), Expect = 3e-41
 Identities = 94/259 (36%), Positives = 147/259 (56%), Gaps = 17/259 (6%)

Query: 17  CGDPTYPPY--VTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           CG P + P     R+ GGEEA P+ WPWQV L++  +    + CGG++I   W+LTAAHC
Sbjct: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHC 616

Query: 75  I---SSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPV 131
           +   ++  ++ +  G H+  + ES         I+VH+D+N+  +S  +DIAL++L++P+
Sbjct: 617 VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNT--LSYDSDIALIQLSSPL 674

Query: 132 SLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAW 191
                ++  CLP +   L ++  C VTGWG +  +G +   LQQ ++ V++   C  + +
Sbjct: 675 EYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYY 734

Query: 192 WG--SSVKTSMICAG--GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYH 247
                 +   MICAG    G    C GDSGGPL C+  +G + ++GIVS+G+  GC    
Sbjct: 735 SAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGA--GCVQPW 792

Query: 248 KPSVFTRVSNYIDWINSVI 266
           KP VF RV  ++DWI S I
Sbjct: 793 KPGVFARVMIFLDWIQSKI 811



 Score =  119 bits (298), Expect = 3e-27
 Identities = 81/254 (31%), Positives = 128/254 (50%), Gaps = 21/254 (8%)

Query: 25  YVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSS-----R 79
           + +R+     +     PWQVSL+       +H CGGSLI    V+TAAHC+ S      +
Sbjct: 43  FFSRISSWRNSTVTGHPWQVSLKSDE----HHFCGGSLIQEDRVVTAAHCLDSLSEKQLK 98

Query: 80  TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQL 139
              V  G ++L+  +     + VSKI+ H ++NS +     DIALL L + V   + +Q 
Sbjct: 99  NITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP-DIALLYLKHKVKFGNAVQP 157

Query: 140 ACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSS--SAWWGSSVK 197
            CLP +   +     C  +GWG++       +VLQ+  L ++D   C++   +     + 
Sbjct: 158 ICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLG 217

Query: 198 TSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSF------GSRLGCNYYHKPS 250
            +M+CAG  D  + +C GDSGGPL C+   G W + GI S+      GS    N + K S
Sbjct: 218 RTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKAS 277

Query: 251 --VFTRVSNYIDWI 262
             +F++VS  +D+I
Sbjct: 278 LGIFSKVSELMDFI 291


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  164 bits (416), Expect = 6e-41
 Identities = 94/255 (36%), Positives = 146/255 (57%), Gaps = 17/255 (6%)

Query: 28  RVVGGEEARPNSWPWQVSLQ-YSSNGKWYHTCGGSLIANSWVLTAAHCI---SSSRTYRV 83
           R+VGG+ A+  +WPW VSLQ ++ N   YHTCGGSL+ + WVLTAAHC    ++   +R+
Sbjct: 42  RIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRL 101

Query: 84  GLGRHNLYVAESGSLAVS-----VSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQ 138
             G   +    +  +        V KI++H+ +NS   ++GNDIAL+++  P+S    I 
Sbjct: 102 VFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNS--ATEGNDIALVEITPPISCGRFIG 159

Query: 139 LACLPPAGTILP-NNYPCYVTGWGRLQTNGAVP-DVLQQGRLLVVDYATCSSSAWWGSSV 196
             CLP     LP  +  C+V GWG ++     P  +L + R+ ++D   C+S+ W+   V
Sbjct: 160 PGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRV 219

Query: 197 KTSMICAGGD-GVISSCNGDSGGPLNCQAS-DGRWQVHGIVSFGSRLGCNYYHKPSVFTR 254
           + + +CAG   G I +C GDSGGPL C+ S +  + V GI S+G  +GC    +P ++T 
Sbjct: 220 QPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWG--VGCARAKRPGIYTA 277

Query: 255 VSNYIDWINSVIANN 269
              Y++WI S I +N
Sbjct: 278 TWPYLNWIASKIGSN 292


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  163 bits (413), Expect = 1e-40
 Identities = 105/285 (36%), Positives = 150/285 (52%), Gaps = 31/285 (10%)

Query: 2   IRTLLLSTLVAG------ALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWY 55
           ++ LLL  L A       + +CG P      +R+VGG + R   WPWQ S+Q+    +  
Sbjct: 7   LQVLLLLVLGAAGTQGRKSAACGQPRMS---SRIVGGRDGRDGEWPWQASIQH----RGA 59

Query: 56  HTCGGSLIANSWVLTAAHCI---SSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWN 112
           H CGGSLIA  WVLTAAHC    +    YRV LG   L      +L+V V ++++  D++
Sbjct: 60  HVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYS 119

Query: 113 SNQISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD- 171
            +      D+ALL+L  PV L+ ++Q  CLP  G   P   PC VTGWG L+    +P+ 
Sbjct: 120 ED--GARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEW 177

Query: 172 -VLQQGRLLVVDYATCSSSAWWGSSVKTS-------MICAG-GDGVISSCNGDSGGPLNC 222
             LQ  R+ ++D  TC      G+ V  +        +CAG   G   +C GDSGGPL C
Sbjct: 178 RPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTC 237

Query: 223 QASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIA 267
             S G W + G+VS+G   GC   ++P V+T V+ Y  WI + ++
Sbjct: 238 LQS-GSWVLVGVVSWGK--GCALPNRPGVYTSVATYSPWIQARVS 279


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  162 bits (409), Expect = 4e-40
 Identities = 89/255 (34%), Positives = 138/255 (54%), Gaps = 19/255 (7%)

Query: 15  LSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           ++CG        +R+VGGE A P +WPWQVSL   +     H CGGS+I   W++TAAHC
Sbjct: 279 IACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN----VHVCGGSIITPEWIVTAAHC 334

Query: 75  ISSSR------TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLA 128
           +          T   G+ R +     +G     V K++ H +++S   +K NDIAL+KL 
Sbjct: 335 VEKPLNNPWHWTAFAGILRQSFMFYGAG---YQVEKVISHPNYDSK--TKNNDIALMKLQ 389

Query: 129 NPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSS 188
            P++  D ++  CLP  G +L     C+++GWG  +  G   +VL   ++L+++   C+S
Sbjct: 390 KPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNS 449

Query: 189 SAWWGSSVKTSMICAGG-DGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYH 247
              + + +  +MICAG   G + SC GDSGGPL   + +  W + G  S+GS  GC   +
Sbjct: 450 RYVYDNLITPAMICAGFLQGNVDSCQGDSGGPL-VTSKNNIWWLIGDTSWGS--GCAKAY 506

Query: 248 KPSVFTRVSNYIDWI 262
           +P V+  V  + DWI
Sbjct: 507 RPGVYGNVMVFTDWI 521


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  162 bits (409), Expect = 4e-40
 Identities = 89/255 (34%), Positives = 138/255 (54%), Gaps = 19/255 (7%)

Query: 15  LSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           ++CG        +R+VGGE A P +WPWQVSL   +     H CGGS+I   W++TAAHC
Sbjct: 242 IACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN----VHVCGGSIITPEWIVTAAHC 297

Query: 75  ISSSR------TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLA 128
           +          T   G+ R +     +G     V K++ H +++S   +K NDIAL+KL 
Sbjct: 298 VEKPLNNPWHWTAFAGILRQSFMFYGAG---YQVEKVISHPNYDSK--TKNNDIALMKLQ 352

Query: 129 NPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSS 188
            P++  D ++  CLP  G +L     C+++GWG  +  G   +VL   ++L+++   C+S
Sbjct: 353 KPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNS 412

Query: 189 SAWWGSSVKTSMICAGG-DGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYH 247
              + + +  +MICAG   G + SC GDSGGPL   + +  W + G  S+GS  GC   +
Sbjct: 413 RYVYDNLITPAMICAGFLQGNVDSCQGDSGGPL-VTSKNNIWWLIGDTSWGS--GCAKAY 469

Query: 248 KPSVFTRVSNYIDWI 262
           +P V+  V  + DWI
Sbjct: 470 RPGVYGNVMVFTDWI 484


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  161 bits (408), Expect = 5e-40
 Identities = 95/254 (37%), Positives = 141/254 (55%), Gaps = 18/254 (7%)

Query: 17  CGDPTYPPYVT--RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           CG       +T  ++V G+ +   +WPWQ S+Q+    K  H CG SLI++ W+L+AAHC
Sbjct: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQW----KGRHYCGASLISSRWLLSAAHC 226

Query: 75  IS---SSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPV 131
            +   +S+ + V  G     V     +   V  I+ H++++S  +   +DIAL++LA  V
Sbjct: 227 FAKKNNSKDWTVNFG----IVVNKPYMTRKVQNIIFHENYSSPGLH--DDIALVQLAEEV 280

Query: 132 SLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAW 191
           S T+ I+  CLP A   L  N    VTGWG L  NG+ P +LQ+  L ++D   C++S  
Sbjct: 281 SFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYA 340

Query: 192 WGSSVKTSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPS 250
           +   V  +M+CAG   G   +C  DSGGPL    S   W + GIVS+G   GC   +KP 
Sbjct: 341 YSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGD--GCGKKNKPG 398

Query: 251 VFTRVSNYIDWINS 264
           V+TRV++Y +WI S
Sbjct: 399 VYTRVTSYRNWITS 412


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  160 bits (404), Expect = 1e-39
 Identities = 106/267 (39%), Positives = 143/267 (53%), Gaps = 27/267 (10%)

Query: 15  LSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           L CG P       R+VGG  A+P +WPWQVSL +       H CGGSLIA SWVL+AAHC
Sbjct: 36  LDCGRPEPS---ARIVGGSNAQPGTWPWQVSLHHGGG----HICGGSLIAPSWVLSAAHC 88

Query: 75  ISSSRT------YRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLA 128
             ++ T      + V LG H+      G+   +V+ IVV    N +Q+  G D+ALL+LA
Sbjct: 89  FMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPA--NYSQVELGADLALLRLA 146

Query: 129 NPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNG--AVPDVLQQGRLLVVDYATC 186
           +P SL   +   CLP A     +   C+ TGWG +Q      +P VLQ+  L ++  ATC
Sbjct: 147 SPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATC 206

Query: 187 ----SSSAWWGSSVK--TSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGS 239
               S    +  +++    M+CAG  +G   +C GDSGGPL C+   GRW   GI SFG 
Sbjct: 207 QCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCE-EGGRWFQAGITSFG- 264

Query: 240 RLGCNYYHKPSVFTRVSNYIDWINSVI 266
             GC   ++P VFT V+ Y  WI   +
Sbjct: 265 -FGCGRRNRPGVFTAVATYEAWIREQV 290



 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 71/255 (27%), Positives = 110/255 (43%), Gaps = 48/255 (18%)

Query: 32  GEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCI---SSSRTYRVGLGRH 88
           G+  RP +WPW+  +    +      C G+L++ SWVL  A C    +SS +    L   
Sbjct: 326 GKAPRPGAWPWEAQVMVPGS----RPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAW 381

Query: 89  NLYVAESGSLAVSVSKIVVHKD--WNSNQISKGNDIALLKLANPVSLTDKIQLACLP-PA 145
            + +  S   A  V+++V H++  W++      +D+ALL+L  PV+L+   +  CLP P 
Sbjct: 382 RV-LLPSRPRAERVARLVQHENASWDN-----ASDLALLQLRTPVNLSAASRPVCLPHPE 435

Query: 146 GTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWW--------GSSV- 196
              LP +  C +  WGR +     P  L +  LL           WW        G++V 
Sbjct: 436 HYFLPGS-RCRLARWGRGEP-ALGPGALLEAELL---------GGWWCHCLYGRQGAAVP 484

Query: 197 ----KTSMICAG--GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPS 250
                   +C        + SC  DS   L CQ  +G W + GI  F S  GC    +P 
Sbjct: 485 LPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQ-EEGTWFLAGIRDFPS--GC---LRPR 538

Query: 251 VFTRVSNYIDWINSV 265
            F  +  +  WI+ V
Sbjct: 539 AFFPLQTHGPWISHV 553



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 64/229 (27%), Positives = 94/229 (41%), Gaps = 25/229 (10%)

Query: 21  TYPPYVTRVVGGE--EARPNS--WPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCI- 75
           T PP+      G   EA P    WPW   +  + +      C G L+A  WVL A HC+ 
Sbjct: 578 TCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGD----RVCTGILLAPGWVLAATHCVL 633

Query: 76  ---SSSRTY-RVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPV 131
              S++  Y  V LGR     A S      VS++V+        +     +ALL+L++ V
Sbjct: 634 RPGSTTVPYIEVYLGRAG---ASSLPQGHQVSRLVISIRL-PQHLGLRPPLALLELSSRV 689

Query: 132 SLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAW 191
             +      CL PAG  +P    C+V GW   Q    V   +    +L      C    +
Sbjct: 690 EPSPSALPICLHPAG--IPPGASCWVLGWKEPQDRVPVAAAVS---ILTQRICDC---LY 741

Query: 192 WGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR 240
            G     ++     +G  + C   S  PL CQ ++G W + G+   GSR
Sbjct: 742 QGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSR 790


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  159 bits (403), Expect = 2e-39
 Identities = 100/257 (38%), Positives = 143/257 (55%), Gaps = 24/257 (9%)

Query: 15  LSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           L+CG     P   RVVGGEEA  +SWPWQVS+QY       H CGGS++   WVLTAAHC
Sbjct: 189 LACGKSLKTP---RVVGGEEASVDSWPWQVSIQYDKQ----HVCGGSILDPHWVLTAAHC 241

Query: 75  ISSSR---TYRVGLGRHNLYVAESGSL-AVSVSKIVVHKDWNSNQISKGNDIALLKLANP 130
                    ++V  G   L     GS  +++V+KI++ +   +    K NDIAL+KL  P
Sbjct: 242 FRKHTDVFNWKVRAGSDKL-----GSFPSLAVAKIIIIE--FNPMYPKDNDIALMKLQFP 294

Query: 131 VSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA-VPDVLQQGRLLVVDYATCSSS 189
           ++ +  ++  CLP     L    P ++ GWG  + NG  + D+L Q  + V+D   C++ 
Sbjct: 295 LTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD 354

Query: 190 AWWGSSVKTSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHK 248
             +   V   M+CAG  +G + +C GDSGGPL  Q+   +W V GIVS+G   GC     
Sbjct: 355 DAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD--QWHVVGIVSWG--YGCGGPST 410

Query: 249 PSVFTRVSNYIDWINSV 265
           P V+T+VS Y++WI +V
Sbjct: 411 PGVYTKVSAYLNWIYNV 427


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  159 bits (403), Expect = 2e-39
 Identities = 100/257 (38%), Positives = 143/257 (55%), Gaps = 24/257 (9%)

Query: 15  LSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
           L+CG     P   RVVGGEEA  +SWPWQVS+QY       H CGGS++   WVLTAAHC
Sbjct: 194 LACGKSLKTP---RVVGGEEASVDSWPWQVSIQYDKQ----HVCGGSILDPHWVLTAAHC 246

Query: 75  ISSSR---TYRVGLGRHNLYVAESGSL-AVSVSKIVVHKDWNSNQISKGNDIALLKLANP 130
                    ++V  G   L     GS  +++V+KI++ +   +    K NDIAL+KL  P
Sbjct: 247 FRKHTDVFNWKVRAGSDKL-----GSFPSLAVAKIIIIE--FNPMYPKDNDIALMKLQFP 299

Query: 131 VSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA-VPDVLQQGRLLVVDYATCSSS 189
           ++ +  ++  CLP     L    P ++ GWG  + NG  + D+L Q  + V+D   C++ 
Sbjct: 300 LTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD 359

Query: 190 AWWGSSVKTSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHK 248
             +   V   M+CAG  +G + +C GDSGGPL  Q+   +W V GIVS+G   GC     
Sbjct: 360 DAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD--QWHVVGIVSWG--YGCGGPST 415

Query: 249 PSVFTRVSNYIDWINSV 265
           P V+T+VS Y++WI +V
Sbjct: 416 PGVYTKVSAYLNWIYNV 432


>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score =  159 bits (401), Expect = 3e-39
 Identities = 101/264 (38%), Positives = 143/264 (54%), Gaps = 30/264 (11%)

Query: 12   AGALSCGDPTYPPYVT--RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVL 69
            + +  CG P   P      +VGG  A P+SWPWQVSL+ +  GK  H CGG+LI+  WVL
Sbjct: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLR-TRFGK--HFCGGTLISPEWVL 1857

Query: 70   TAAHCISSSR---TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLK 126
            TAAHC+  S    +Y+V LG H     ES    + VS++ +             DIALLK
Sbjct: 1858 TAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQA--------DIALLK 1909

Query: 127  LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQ-TNGAVPDVLQQGRLLVVDYAT 185
            L+ P  +TDK+  ACLP    ++     CY+TGWG  Q T G    +L++ +LLV++   
Sbjct: 1910 LSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGT--GLLKEAQLLVIENEV 1967

Query: 186  CSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNY 245
            C+   +    +    +  G D    SC GDSGGPL C   D ++ + G+ S+G  LGC  
Sbjct: 1968 CNHYKY----ICAEHLARGTD----SCQGDSGGPLVCFEKD-KYILQGVTSWG--LGCAR 2016

Query: 246  YHKPSVFTRVSNYIDWINSVIANN 269
             +KP V+ RVS ++ WI  ++ NN
Sbjct: 2017 PNKPGVYARVSRFVTWIEGMMRNN 2040


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  157 bits (398), Expect = 7e-39
 Identities = 103/263 (39%), Positives = 142/263 (53%), Gaps = 23/263 (8%)

Query: 7   LSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANS 66
           L TL  G   CG P       R+VGG  A   +WPWQ SL+     +  H CGGSL++  
Sbjct: 19  LRTLQPG---CGRPQVSDAGGRIVGGHAAPAGAWPWQASLRL----RRVHVCGGSLLSPQ 71

Query: 67  WVLTAAHCIS---SSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIA 123
           WVLTAAHC S   +S  Y+V LG   + ++   S   +V +I++H    S Q     DIA
Sbjct: 72  WVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFS---TVRQIILHSS-PSGQPGTSGDIA 127

Query: 124 LLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD--VLQQGRLLVV 181
           L++L+ PV+L+ +I   CLP A         C+VTGWG  +    +P    L++ ++ VV
Sbjct: 128 LVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVV 187

Query: 182 DYATCSSS--AWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGS 239
           D  TC        GS ++  M+CA G G   +C  DSGGPL CQ  +G W   GIVS+G 
Sbjct: 188 DTETCRRDYPGPGGSILQPDMLCARGPG--DACQDDSGGPLVCQV-NGAWVQAGIVSWGE 244

Query: 240 RLGCNYYHKPSVFTRVSNYIDWI 262
             GC   ++P V+TRV  Y++WI
Sbjct: 245 --GCGRPNRPGVYTRVPAYVNWI 265


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  155 bits (392), Expect = 3e-38
 Identities = 90/241 (37%), Positives = 135/241 (56%), Gaps = 13/241 (5%)

Query: 27  TRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISS---SRTYRV 83
           TR+VGG  +    WPWQVSLQ     +  H CGGSLI + WVLTAAHC         +R+
Sbjct: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447

Query: 84  GLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN-DIALLKLANPVSLTDKIQLACL 142
             G  NL      +    + +I++H+++   ++S+GN DIAL+KL  P++ T+  +  CL
Sbjct: 448 YSGILNLSDITKDTPFSQIKEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICL 504

Query: 143 PPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMIC 202
           P  G        C+VTGWG  +  G + ++LQ+  + +V    C    +    +   M+C
Sbjct: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVC 563

Query: 203 AG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDW 261
           AG  +G   +C GDSGGPL C+  +G W++ GI S+G   GC    +P V+T+V+ Y+DW
Sbjct: 564 AGYKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWGE--GCARREQPGVYTKVAEYMDW 620

Query: 262 I 262
           I
Sbjct: 621 I 621


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  154 bits (390), Expect = 6e-38
 Identities = 90/240 (37%), Positives = 140/240 (58%), Gaps = 15/240 (6%)

Query: 28  RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRT---YRVG 84
           R+VGG EA P  +PWQ SL+ +      H CG ++I   W+++AAHC +  +    +   
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKE----HFCGAAIINARWLVSAAHCFNEFQDPTKWVAY 257

Query: 85  LGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPP 144
           +G   L  +E+ ++   V +IV H  +N++  +   D+A+L+L +P+     IQ  CLP 
Sbjct: 258 VGATYLSGSEASTVRAQVVQIVKHPLYNAD--TADFDVAVLELTSPLPFGRHIQPVCLPA 315

Query: 145 AGTILPNNYPCYVTGWGRLQTNGAV-PDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICA 203
           A  I P +  C ++GWG L+ +  V P+VLQ+  + ++D A C+S   +G S+   M+CA
Sbjct: 316 ATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASL--YGHSLTDRMVCA 373

Query: 204 GG-DGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWI 262
           G  DG + SC GDSGGPL C+   GR+ + GIVS+G  +GC    +P V+ RV+   DWI
Sbjct: 374 GYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWG--IGCAEARRPGVYARVTRLRDWI 431



 Score =  153 bits (386), Expect = 2e-37
 Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 14/256 (5%)

Query: 17  CGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCIS 76
           CG        TRVVGG  A     PWQVSL+  S     H CG +++ + W+L+AAHC +
Sbjct: 492 CGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSR----HFCGATVVGDRWLLSAAHCFN 547

Query: 77  SSRT--YRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLT 134
            ++    R  LG  +L       + + + ++V+H  +N   +    D+A+L+LA+P++  
Sbjct: 548 HTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDF--DLAVLELASPLAFN 605

Query: 135 DKIQLACLPPAGTILPNNYPCYVTGWGRLQT-NGAVPDVLQQGRLLVVDYATCSSSAWWG 193
             IQ  CLP A    P    C ++GWG  Q  N   P++LQ+  + ++D  TC  S  + 
Sbjct: 606 KYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTC--SVLYN 663

Query: 194 SSVKTSMICAGG-DGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVF 252
            S+   MICAG  +G + SC GDSGGPL C+ + G + + GIVS+G  +GC    KP V+
Sbjct: 664 FSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWG--IGCAQVKKPGVY 721

Query: 253 TRVSNYIDWINSVIAN 268
           TR++    WI  ++++
Sbjct: 722 TRITRLKGWILEIMSS 737



 Score =  144 bits (364), Expect = 6e-35
 Identities = 89/248 (35%), Positives = 129/248 (52%), Gaps = 15/248 (6%)

Query: 23   PPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCIS---SSR 79
            P  +TR+VGG  A    WPWQVSL         H CG  L+A  W+L+AAHC       +
Sbjct: 821  PAALTRIVGGSAAGRGEWPWQVSLWLRRRE---HRCGAVLVAERWLLSAAHCFDVYGDPK 877

Query: 80   TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQL 139
             +   LG   L  AE G L   V++I  H  +N   +    D+ALL+LA PV  +  ++ 
Sbjct: 878  QWAAFLGTPFLSGAE-GQLE-RVARIYKHPFYNLYTLDY--DVALLELAGPVRRSRLVRP 933

Query: 140  ACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTS 199
             CLP      P+   C +TGWG ++  G++   LQ+  + ++   TC    ++   + + 
Sbjct: 934  ICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTC--RRFYPVQISSR 991

Query: 200  MICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNY 258
            M+CAG   G + SC+GD+GGPL C+   GRW + G+ S+G   GC   H P V+TRV+  
Sbjct: 992  MLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWG--YGCGRPHFPGVYTRVAAV 1049

Query: 259  IDWINSVI 266
              WI   I
Sbjct: 1050 RGWIGQHI 1057


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  153 bits (387), Expect = 1e-37
 Identities = 91/251 (36%), Positives = 129/251 (51%), Gaps = 21/251 (8%)

Query: 28  RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSR---TYRVG 84
           R+ GG  A    WPWQVS+ Y       H CGGSL++  WVL+AAHC  S      Y V 
Sbjct: 44  RITGGSSAVAGQWPWQVSITYEG----VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVK 99

Query: 85  LGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPP 144
           LG H L      +   ++  I+ H  +   Q     DIALL+L+ P++ +  I+  CLP 
Sbjct: 100 LGAHQLDSYSEDAKVSTLKDIIPHPSYL--QEGSQGDIALLQLSRPITFSRYIRPICLPA 157

Query: 145 AGTILPNNYPCYVTGWGRLQTNGAV--PDVLQQGRLLVVDYATCS------SSAWWGSSV 196
           A    PN   C VTGWG +  + ++  P  LQQ  + ++   TC+      +       V
Sbjct: 158 ANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFV 217

Query: 197 KTSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRV 255
           +  M+CAG  +G   +C GDSGGPL+C   +G W + GIVS+G    C   ++P V+T  
Sbjct: 218 QEDMVCAGYVEGGKDACQGDSGGPLSCPV-EGLWYLTGIVSWGD--ACGARNRPGVYTLA 274

Query: 256 SNYIDWINSVI 266
           S+Y  WI S +
Sbjct: 275 SSYASWIQSKV 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,137,227
Number of Sequences: 37866
Number of extensions: 490278
Number of successful extensions: 1787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 983
Number of HSP's gapped (non-prelim): 223
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.