Guide to the Human Genome
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Search of human proteins with 155030236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
         (1337 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]      2812   0.0  
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]      2791   0.0  
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]                      93   2e-18
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    89   2e-17
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]                      87   1e-16
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]                       87   1e-16
gi|119226260 calcium homeostasis endoplasmic reticulum protein [...    86   2e-16
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    84   9e-16
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    79   2e-14
gi|52426743 cisplatin resistance-associated overexpressed protei...    79   3e-14
gi|19923485 cisplatin resistance-associated overexpressed protei...    79   3e-14
gi|160707881 formin 2 [Homo sapiens]                                   79   4e-14
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    78   6e-14
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    78   6e-14
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    78   6e-14
gi|11386183 WAS protein family, member 2 [Homo sapiens]                77   8e-14
gi|47132519 Ras association and pleckstrin homology domains 1 is...    77   1e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    75   3e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    75   4e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    75   5e-13
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                74   9e-13
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    74   9e-13
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    74   1e-12
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    74   1e-12
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    74   1e-12
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    74   1e-12
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 74   1e-12
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                73   2e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            72   3e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    72   3e-12

>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 2812 bits (7289), Expect = 0.0
 Identities = 1337/1337 (100%), Positives = 1337/1337 (100%)

Query: 1    MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60
            MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
Sbjct: 1    MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60

Query: 61   TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120
            TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
Sbjct: 61   TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120

Query: 121  PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180
            PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
Sbjct: 121  PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180

Query: 181  SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240
            SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
Sbjct: 181  SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240

Query: 241  GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300
            GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
Sbjct: 241  GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300

Query: 301  PSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMP 360
            PSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMP
Sbjct: 301  PSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMP 360

Query: 361  DKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQE 420
            DKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQE
Sbjct: 361  DKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQE 420

Query: 421  KAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDR 480
            KAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDR
Sbjct: 421  KAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDR 480

Query: 481  LHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRIT 540
            LHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRIT
Sbjct: 481  LHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRIT 540

Query: 541  VSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMP 600
            VSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMP
Sbjct: 541  VSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMP 600

Query: 601  ENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVL 660
            ENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVL
Sbjct: 601  ENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVL 660

Query: 661  SMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQL 720
            SMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQL
Sbjct: 661  SMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQL 720

Query: 721  DREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQK 780
            DREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQK
Sbjct: 721  DREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQK 780

Query: 781  LAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLM 840
            LAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLM
Sbjct: 781  LAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLM 840

Query: 841  HLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHM 900
            HLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHM
Sbjct: 841  HLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHM 900

Query: 901  RKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLA 960
            RKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLA
Sbjct: 901  RKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLA 960

Query: 961  TYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSL 1020
            TYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSL
Sbjct: 961  TYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSL 1020

Query: 1021 EEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVI 1080
            EEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVI
Sbjct: 1021 EEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVI 1080

Query: 1081 FTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLL 1140
            FTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLL
Sbjct: 1081 FTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLL 1140

Query: 1141 RSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYV 1200
            RSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYV
Sbjct: 1141 RSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYV 1200

Query: 1201 HTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHART 1260
            HTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHART
Sbjct: 1201 HTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHART 1260

Query: 1261 YTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRW 1320
            YTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRW
Sbjct: 1261 YTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRW 1320

Query: 1321 EREHQEREPDETEDIKK 1337
            EREHQEREPDETEDIKK
Sbjct: 1321 EREHQEREPDETEDIKK 1337


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 2791 bits (7236), Expect = 0.0
 Identities = 1336/1374 (97%), Positives = 1336/1374 (97%), Gaps = 37/1374 (2%)

Query: 1    MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60
            MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
Sbjct: 1    MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60

Query: 61   TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120
            TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
Sbjct: 61   TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120

Query: 121  PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180
            PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
Sbjct: 121  PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180

Query: 181  SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240
            SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
Sbjct: 181  SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240

Query: 241  GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300
            GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
Sbjct: 241  GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300

Query: 301  PSLERSYKKEYKRSGS-------------------------------------RSPSREK 323
            PSLERSYKKEYKRSG                                      RSPSREK
Sbjct: 301  PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK 360

Query: 324  KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 383
            KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
Sbjct: 361  KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 420

Query: 384  YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 443
            YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
Sbjct: 421  YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 480

Query: 444  SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 503
            SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
Sbjct: 481  SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 540

Query: 504  KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 563
            KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
Sbjct: 541  KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 600

Query: 564  FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 623
            FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
Sbjct: 601  FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 660

Query: 624  DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 683
            DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
Sbjct: 661  DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 720

Query: 684  NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 743
            NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
Sbjct: 721  NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 780

Query: 744  QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 803
            QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
Sbjct: 781  QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 840

Query: 804  ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 863
            ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
Sbjct: 841  ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 900

Query: 864  SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 923
            SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
Sbjct: 901  SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 960

Query: 924  RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 983
            RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
Sbjct: 961  RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 1020

Query: 984  FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1043
            FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
Sbjct: 1021 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1080

Query: 1044 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1103
            YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
Sbjct: 1081 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1140

Query: 1104 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1163
            GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
Sbjct: 1141 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1200

Query: 1164 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1223
            ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
Sbjct: 1201 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1260

Query: 1224 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1283
            PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
Sbjct: 1261 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1320

Query: 1284 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1337
            EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
Sbjct: 1321 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1374


>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
          Length = 588

 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 85/264 (32%), Positives = 106/264 (40%), Gaps = 36/264 (13%)

Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173
           PP FPP  PP   P  P +P  PP   T P ++PPP +P   PPP  P       PPG  
Sbjct: 342 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGIPITVPPPGFPP------PPG-- 392

Query: 174 HHNFPPPS-FNSFQNNPSSFLPSANNSSSPH----FRHLPPYPLPKAPS----------- 217
               PPPS   + ++  SS   S +  + P+    F HLP    P  PS           
Sbjct: 393 ---APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG-SAPSWPSLVDTSKQWDYY 448

Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPS 276
            RR  +R +  D  R RD    R ER R+   RER R  D     S + SD +R R    
Sbjct: 449 ARREKDRDRERDRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREY 504

Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWS 336
             R YER R    +  RHR+ R     E  +K     S  R  S E    R    K + S
Sbjct: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKS 562

Query: 337 DNQSSGKDKNYTSIKEKEPEETMP 360
                GK+       E+E  E  P
Sbjct: 563 KRSKEGKEAGSEPAPEQESTEATP 586


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 104/369 (28%), Positives = 128/369 (34%), Gaps = 92/369 (24%)

Query: 19  PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDF 78
           P+G  G G  P A    P   R   P  P        P  P       P P   PP P  
Sbjct: 198 PQGGRGRGRFPGAV---PGGDRFPGPAGPG------GPPPPFPAGQTPPRPPLGPPGPPG 248

Query: 79  VPFPPP----MPPSAQGP-----LPPCPI--------RPPFPNHQMRHPFPVPPCFPPMP 121
            P PPP    +PP   GP      PP P+        +PP        P PVP   PP  
Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308

Query: 122 PPMPCPNNPP----VPGAPPGQGTFPF-MMPPPSMPHPPP----------PPVMPQQVN- 165
           PP P    PP     P  PPG    P  + PPP +P PPP          P   P   N 
Sbjct: 309 PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368

Query: 166 ---------------YQYPPGYSHHNFPPP--------------SFNSFQNNPSSFLPSA 196
                          Y  PP Y   ++ PP               F    N   +   SA
Sbjct: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSA 428

Query: 197 -----NNSSSPHF--------RHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243
                +++S+  +          +      K  ++ R    +    D  H   S   G  
Sbjct: 429 ISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYG-- 486

Query: 244 HRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSL 303
             S  RRER R  D  R  SR +S   + R+  RH  Y R R RERERHR RD  R    
Sbjct: 487 --SGSRRERSRERDHSR--SREKSRRHKSRSRDRHDDYYRERSRERERHRDRD--RDRDR 540

Query: 304 ERSYKKEYK 312
           ER  ++EY+
Sbjct: 541 ERDREREYR 549



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 94/339 (27%), Positives = 122/339 (35%), Gaps = 66/339 (19%)

Query: 19  PRGRGGH------GARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFL 72
           P G GG       G  P  P   P          PP Q    P + P       P P   
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279

Query: 73  PPRPDFVPFPPPMPPSAQGPLPPCPIR--PPFPNHQMRHPFPVPPCFPPMPP-----PMP 125
           P +P   P   P+PP   GP PP P    PP P    + P P P  FPP PP     P+ 
Sbjct: 280 PGQPFGQPPLGPLPP---GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336

Query: 126 CPNNPPVPGAPPGQG-----TFPFMMPPPSMPHPP------PPPVMPQQVNYQYPPGYSH 174
               P +PG PPG         P   PPP+    P      PPP  P    Y  PP Y  
Sbjct: 337 LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDP----YGRPPPYDR 392

Query: 175 HNFPPPS--------------FNSFQNNPSSFLPSA-----NNSSSPHFRH--------L 207
            ++ PP               F    N   +   SA     +++S+  +          +
Sbjct: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAI 452

Query: 208 PPYPLPKAPSERRSPERLKHYDDHRH--RDHSHGRGERHRSLDRRERGRSPDR-RRQDSR 264
                 K  ++ R    +    D  H     S+G G R      R+  RS ++ RR  SR
Sbjct: 453 SLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSR 512

Query: 265 YRSDYD-----RGRTPSRHRSYERSRERERERHRHRDNR 298
            R  +D     R R   RHR  +R R+RER+R R   +R
Sbjct: 513 SRDRHDDYYRERSRERERHRDRDRDRDRERDREREYRHR 551


>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
          Length = 520

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 79/253 (31%), Positives = 99/253 (39%), Gaps = 23/253 (9%)

Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171
           PP FPP  PP   P  P +P  PP   T P ++PPP  P PP  PPP +   +   +  G
Sbjct: 283 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 341

Query: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228
           Y   S   FP      + N     LP     S+P +  L           RR  +R +  
Sbjct: 342 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 391

Query: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287
           D  R RD    R ER R+   RER R  D     S + SD +R R      R YER R  
Sbjct: 392 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 447

Query: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNY 347
             +  RHR+ R     E  +K     S  R  S E    R    K + S     GK+   
Sbjct: 448 REKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKSKRSKEGKEAGS 505

Query: 348 TSIKEKEPEETMP 360
               E+E  E  P
Sbjct: 506 EPAPEQESTEATP 518


>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
          Length = 594

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 79/253 (31%), Positives = 99/253 (39%), Gaps = 23/253 (9%)

Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171
           PP FPP  PP   P  P +P  PP   T P ++PPP  P PP  PPP +   +   +  G
Sbjct: 357 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 415

Query: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228
           Y   S   FP      + N     LP     S+P +  L           RR  +R +  
Sbjct: 416 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 465

Query: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287
           D  R RD    R ER R+   RER R  D     S + SD +R R      R YER R  
Sbjct: 466 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 521

Query: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNY 347
             +  RHR+ R     E  +K     S  R  S E    R    K + S     GK+   
Sbjct: 522 REKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKSKRSKEGKEAGS 579

Query: 348 TSIKEKEPEETMP 360
               E+E  E  P
Sbjct: 580 EPAPEQESTEATP 592


>gi|119226260 calcium homeostasis endoplasmic reticulum protein
           [Homo sapiens]
          Length = 916

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 88/314 (28%), Positives = 114/314 (36%), Gaps = 41/314 (13%)

Query: 80  PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP-VPPCF--PPMPPPMPCPNNPPVPGAP 136
           PF    PP  +GP PP    P F      H F   PP F     PP  P    P      
Sbjct: 513 PFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFD 572

Query: 137 PGQGTFPFMMPPPS------MPHPP----PPPVMPQQVNYQYPP-------------GYS 173
             QG FP  M PP       MPHP     PP   PQ  ++  PP             G  
Sbjct: 573 YPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPP 632

Query: 174 HHNFPPPSFNS---FQNNPSSFLPSANNSSSPHFRHLPP----YPLPKAPSERRSPERLK 226
           H N   PS      + + P+  +          ++ L P     P P  PSER       
Sbjct: 633 HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEA 692

Query: 227 HYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRE 286
            Y    H    +  G     L    R +   RRR+    R+       PSR RS  +SR 
Sbjct: 693 FYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNS-----GPSRSRSRSKSRG 747

Query: 287 RERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKN 346
           R   R   R ++ S S  RS  +   RS SRS SR + R+R    + R   +QS  + K+
Sbjct: 748 RSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSR---SQSRSRSKS 804

Query: 347 YTSIKEKEPEETMP 360
           Y+  + +      P
Sbjct: 805 YSPGRRRRSRSRSP 818



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 71/292 (24%), Positives = 91/292 (31%), Gaps = 63/292 (21%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR--PP 101
           P  PP      P   P+T   +S  P  +P   ++        P+A GP  P P    PP
Sbjct: 357 PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPP 416

Query: 102 FPNHQMRHPFPVPPC---FPPMPPPMPCPNNPPVPGAPP-------------------GQ 139
                   P PV P     PP  PP P     P P  PP                   GQ
Sbjct: 417 NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGP-PHCPPWNNSHEGMWGEQRGDPGWNGQ 475

Query: 140 GTFP------------FMMPPPSMPHPPP-------PPV---MPQQVNYQYPPGYSHHNF 177
              P            F  P  S    PP       PP     P      +PP   H  F
Sbjct: 476 RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQF 535

Query: 178 -PPPSFNSFQNNPSSFL----PSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHR 232
             PP  ++F   P  F+    P  +    P + H   YP    P+E   P    H+  HR
Sbjct: 536 NQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPH---HHPGHR 592

Query: 233 H-----RDHSHGRGERHRSL---DRRERGRSPDRRRQDSRYRSDYDRGRTPS 276
                  +H    G +H           G+ P  RRQ   + +  D    P+
Sbjct: 593 MPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPN 644



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 12/111 (10%)

Query: 82  PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT 141
           PPP PP A  P P  P     P  Q       PP   P       P     P A   +G 
Sbjct: 356 PPPAPPPAPAPAPAIP-----PTTQPDD--SKPPIQMPGSSEYEAPGGVQDPAAAGPRGP 408

Query: 142 FPFMMPPPSMP--HPPPPPVMP--QQVNYQYPPGYSHHNFPPPSFNSFQNN 188
            P    PP+ P     P PV P  QQ   + PP Y HH   PP    + N+
Sbjct: 409 GPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPP-YPHHQGGPPHCPPWNNS 458



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 25/94 (26%), Positives = 33/94 (35%), Gaps = 17/94 (18%)

Query: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPV-MPQQVNYQYPPGYSH-----------HNF 177
           PP P  PP     P  +PP + P    PP+ MP    Y+ P G              H+ 
Sbjct: 355 PPPPAPPPAPAPAP-AIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQ 413

Query: 178 PPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYP 211
            PP+   + + P    P             PPYP
Sbjct: 414 IPPNKPPWFDQPHPVAPWGQQQPPEQ----PPYP 443


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 74/231 (32%), Positives = 97/231 (41%), Gaps = 38/231 (16%)

Query: 21  GRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVP 80
           G+ G G    APS R  N  +  P  PP       P   +T+ ++  A    PPRP+   
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPAS-----PRLGNTSEAHGAART-APPRPNVPA 173

Query: 81  FPPPMPPSAQGPLPP-----CPIR-----PPFPNHQMRHPFPVPP--CFPPMPPPMPCPN 128
            PPP PP    PLPP      PI+     PP P  +   P   PP  C PP PPP P P 
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233

Query: 129 NPPVPGAP--PGQGTFPFMMPPPSMPHPPPPPVMP-------------QQVNYQYPPGYS 173
            PP+P A     +   P + P    P PPP P++P                + Q PP   
Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP 293

Query: 174 HHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPER 224
               P  S +   + P+  LP  N+SS       PP P PK+PS +  P++
Sbjct: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETP----PPLP-PKSPSFQAPPQK 339



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 58/199 (29%), Positives = 68/199 (34%), Gaps = 70/199 (35%)

Query: 25  HGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPA------------PNFL 72
           HGA  +AP  RP N+    P  PP      PP  PS++   +P             P   
Sbjct: 159 HGAARTAPP-RP-NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVA 216

Query: 73  PPRPDFVPFPPPMPPSAQGPLPPC------------------PIRPPFP----------- 103
           PP P   P PPP PP    PLPP                   PI PP P           
Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLK 276

Query: 104 ------NHQMRHPFPVPPCFPPMPPPMPCPNN-----PPVPGA-------PPGQGTFPFM 145
                     + P P PP  PP+PP   C        PP+PG        PP     P  
Sbjct: 277 AEPASPAQDAQEP-PAPP--PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF 333

Query: 146 MPPP------SMPHPPPPP 158
             PP      ++P PP PP
Sbjct: 334 QAPPQKAGAQALPAPPAPP 352



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 42/134 (31%), Positives = 49/134 (36%), Gaps = 35/134 (26%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSP-----APNFLPPRPDFVPFPPPM--------PPS-- 88
           P  PP      PP  P++  S+       AP  LPP P  +P  PP         P S  
Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283

Query: 89  --AQGPLPPCPIRPPFPNHQMRHPFPVPPCF---------PPMPPPMPCPNNPP------ 131
             AQ P  P P  PP+ +   R   P PP           PP+PP  P    PP      
Sbjct: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343

Query: 132 ---VPGAPPGQGTF 142
               P APPG   F
Sbjct: 344 ALPAPPAPPGSQPF 357



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 1/28 (3%)

Query: 110 PFPVPPCFPPMPPPMPCPNNPPVPGAPP 137
           P P PP  PP PPP+  P  PP P APP
Sbjct: 4   PPPPPPPLPPPPPPLGAP-PPPPPSAPP 30



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 21/41 (51%), Positives = 22/41 (53%), Gaps = 13/41 (31%)

Query: 112 PVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMP 152
           PVPP   P PPP+P P  PP  GAPP         PPPS P
Sbjct: 2   PVPP---PPPPPLPPP--PPPLGAPP--------PPPPSAP 29



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 23/54 (42%)

Query: 79  VPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132
           +P PPP PP    PLPP                P PP   P PPP   P+ PPV
Sbjct: 1   MPVPPPPPP----PLPP----------------PPPPLGAPPPPP---PSAPPV 31



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 7/54 (12%)

Query: 120 MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173
           MP P P P  PP+P  PP     P   PPP  P  PP       +    P G S
Sbjct: 1   MPVPPPPP--PPLPPPPP-----PLGAPPPPPPSAPPVSTDTSSLRRADPKGRS 47



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 14/43 (32%)

Query: 119 PMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMP 161
           P+PPP P    PP+P  PP          P   P PPPP   P
Sbjct: 2   PVPPPPP----PPLPPPPP----------PLGAPPPPPPSAPP 30


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 58/160 (36%), Positives = 66/160 (41%), Gaps = 18/160 (11%)

Query: 26  GARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPP-- 83
           GA  +AP+  P     L PQ P       PP  P       P    +PPRP   P PP  
Sbjct: 221 GAYYAAPALDPALCVHLVPQLP------RPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMA 274

Query: 84  PMPP-SAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMP--PPM-PCPNNPPVPGAPPGQ 139
           P+PP S   P+PP P   P P      P P  P   P+P  PPM P P  PP+   PPG 
Sbjct: 275 PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGP 334

Query: 140 GTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPP 179
                   PP  P PP PP+ P       PPG      PP
Sbjct: 335 PMARVPPGPPMAPLPPGPPMAP------LPPGPPMAPLPP 368



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 49/138 (35%), Positives = 57/138 (41%), Gaps = 21/138 (15%)

Query: 32  PSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNS----PAPNF--LPPRPDFVPFP--P 83
           P   P+   +  P +PP+     PP AP    S      P P    +PP P   P P  P
Sbjct: 250 PPMPPRPPMVPMPPRPPIAPM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP 307

Query: 84  PMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFP 143
           PM P   GP P  P+ PP P      P P     PP PP  P P  PP+   PPG     
Sbjct: 308 PMAPVPTGP-PMAPV-PPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG----- 360

Query: 144 FMMPPPSMPHPPPPPVMP 161
               PP  P PP PP+ P
Sbjct: 361 ----PPMAPLPPGPPMAP 374



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 26/79 (32%), Positives = 28/79 (35%)

Query: 55  PPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114
           PP  P       P    +PP P     PP  P +   P PP    PP P      P P  
Sbjct: 304 PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPM 363

Query: 115 PCFPPMPPPMPCPNNPPVP 133
              PP PP  P P    VP
Sbjct: 364 APLPPGPPMAPLPPRSHVP 382



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 21/52 (40%), Positives = 22/52 (42%), Gaps = 5/52 (9%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPP 95
           P  PP+     PP  P       P    LPP P   P PP  PP A  PLPP
Sbjct: 331 PPGPPMARV--PPGPPMAPLPPGPPMAPLPPGPPMAPLPPG-PPMA--PLPP 377


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 59/164 (35%), Positives = 79/164 (48%), Gaps = 14/164 (8%)

Query: 214 KAPSERRSPERLKHYDDH-RHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRG 272
           K   E R  ER +  ++  R R       E+ R+ DR  R RS  R R  SR  SD    
Sbjct: 251 KQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR-TSD---- 305

Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARW---- 328
           R  SR R ++RSR RER R R RD RRS S +RS +K   RS  R  S+ + R  +    
Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365

Query: 329 ---EEEKDRWS-DNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368
              + E+DR S + +  G D   +S+K    E+   D N E +E
Sbjct: 366 KSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKE 409



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 44/138 (31%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYRSDYDR 271
           ++ S  R   R       R RDH   R  ER RS  R R R RS DR  +  R RS  DR
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR-DR 350

Query: 272 GRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEE 331
            R+ SR R   + R + R+R + R ++         KK   +SGSR    E       E 
Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT---ES 407

Query: 332 KDRWSDNQSSGKDKNYTS 349
           K+  + N+ +G  ++  S
Sbjct: 408 KESDTKNEVNGTSEDIKS 425



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%)

Query: 219 RRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRH 278
           +RS  R +H      R  S  R  +      R R RS DRRR  S  RS+  + R+ SR 
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER-KHRSRSRD 349

Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDN 338
           R   +SR+R+   ++HR   R    +R  K++ KR      S  K  +R ++ +D  +++
Sbjct: 350 RRRSKSRDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407

Query: 339 QSS 341
           + S
Sbjct: 408 KES 410



 Score = 30.8 bits (68), Expect = 9.1
 Identities = 40/197 (20%), Positives = 73/197 (37%), Gaps = 28/197 (14%)

Query: 277 RHRSYERSRERERE-RHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRW 335
           +H  Y + +    E + + R     P  +   KKE +        REK+R R  EE++R 
Sbjct: 216 QHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQER----EEREKEREREREERERK 271

Query: 336 SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGD 395
              +   ++K     +E+        ++     +       RC+ S ++  S   ++   
Sbjct: 272 RRREEEEREKERARDRERRKRSRSRSRHSSRTSDR------RCSRSRDHKRSRSRER--- 322

Query: 396 STVVGTSRLRD-----LYDKFEEELGS-----RQEKAKAARPPWEPPKTKLDEDLESSSE 445
                 SR RD      +D+ E +  S     R+ K++  +      K++  E    S E
Sbjct: 323 ----RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378

Query: 446 SECESDEDSTCSSSSDS 462
            E    +D   S  S S
Sbjct: 379 KEKRGSDDKKSSVKSGS 395


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 59/164 (35%), Positives = 79/164 (48%), Gaps = 14/164 (8%)

Query: 214 KAPSERRSPERLKHYDDH-RHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRG 272
           K   E R  ER +  ++  R R       E+ R+ DR  R RS  R R  SR  SD    
Sbjct: 251 KQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR-TSD---- 305

Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARW---- 328
           R  SR R ++RSR RER R R RD RRS S +RS +K   RS  R  S+ + R  +    
Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365

Query: 329 ---EEEKDRWS-DNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368
              + E+DR S + +  G D   +S+K    E+   D N E +E
Sbjct: 366 KSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKE 409



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 44/138 (31%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYRSDYDR 271
           ++ S  R   R       R RDH   R  ER RS  R R R RS DR  +  R RS  DR
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR-DR 350

Query: 272 GRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEE 331
            R+ SR R   + R + R+R + R ++         KK   +SGSR    E       E 
Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT---ES 407

Query: 332 KDRWSDNQSSGKDKNYTS 349
           K+  + N+ +G  ++  S
Sbjct: 408 KESDTKNEVNGTSEDIKS 425



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%)

Query: 219 RRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRH 278
           +RS  R +H      R  S  R  +      R R RS DRRR  S  RS+  + R+ SR 
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER-KHRSRSRD 349

Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDN 338
           R   +SR+R+   ++HR   R    +R  K++ KR      S  K  +R ++ +D  +++
Sbjct: 350 RRRSKSRDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407

Query: 339 QSS 341
           + S
Sbjct: 408 KES 410



 Score = 30.8 bits (68), Expect = 9.1
 Identities = 40/197 (20%), Positives = 73/197 (37%), Gaps = 28/197 (14%)

Query: 277 RHRSYERSRERERE-RHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRW 335
           +H  Y + +    E + + R     P  +   KKE +        REK+R R  EE++R 
Sbjct: 216 QHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQER----EEREKEREREREERERK 271

Query: 336 SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGD 395
              +   ++K     +E+        ++     +       RC+ S ++  S   ++   
Sbjct: 272 RRREEEEREKERARDRERRKRSRSRSRHSSRTSDR------RCSRSRDHKRSRSRER--- 322

Query: 396 STVVGTSRLRD-----LYDKFEEELGS-----RQEKAKAARPPWEPPKTKLDEDLESSSE 445
                 SR RD      +D+ E +  S     R+ K++  +      K++  E    S E
Sbjct: 323 ----RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378

Query: 446 SECESDEDSTCSSSSDS 462
            E    +D   S  S S
Sbjct: 379 KEKRGSDDKKSSVKSGS 395


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 68/198 (34%), Positives = 82/198 (41%), Gaps = 26/198 (13%)

Query: 44   PQQPPVQ-YQYEPPSAPSTTFSNSPAPNFLP-----PRPDF----VPFPPPMPPSAQGPL 93
            PQ PP+Q  +  PP  P    +  P P  LP     P P      +P PPP+P +A  P 
Sbjct: 897  PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956

Query: 94   PPCP-----IRPPFPNHQMRHPFPVPPCFPPMPPPMPC---PNNPPVPGA---PPGQGTF 142
            PP P     + PP P   +  P P+P    P PPP+P    P  PP+PGA   PP     
Sbjct: 957  PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016

Query: 143  PFMMPPPSMPHP--PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200
              + PPP +P    PPPP +P       PP       PPP        P   LP A    
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076

Query: 201  SPHFRHL---PPYPLPKA 215
             P        PP PLP A
Sbjct: 1077 PPPLPGAGIPPPPPLPGA 1094



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 62/190 (32%), Positives = 74/190 (38%), Gaps = 23/190 (12%)

Query: 44   PQQPPVQYQYEPPSAPSTTFSNSPAPNF----LPPRPDF----VPFPPPMPPSAQGPLPP 95
            P  PP+     PP  P       P P      +PP P      +P PPP+P +   P PP
Sbjct: 976  PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035

Query: 96   CPIR-----PPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPS 150
             P       PP P   +  P P+P    P PPP+P    PP P   PG G    + PPP 
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAG----IPPPPP 1090

Query: 151  MPHP--PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHL- 207
            +P    PPPP +P       PP       PPP        P   LP A     P    + 
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150

Query: 208  --PPYPLPKA 215
              PP PLP A
Sbjct: 1151 IPPPPPLPGA 1160



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 55/170 (32%), Positives = 67/170 (39%), Gaps = 33/170 (19%)

Query: 44   PQQPPVQYQYEPPSAPSTTFSNSPAPNF----LPPRPDF----VPFPPPMPPSAQGPLPP 95
            P  PP+     PP  P       P P      +PP P      +P PPP+P     P PP
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156

Query: 96   CPIR-----PPFPNHQMRHPFPVPPCFPPMPPPMPC---PNNPPVPGAP-------PGQG 140
             P       PP P   +  P P+P    P PPP+P    P  PP+PGA        PG G
Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216

Query: 141  TFPF---MMPPPSMPHPPP-------PPVMPQQVNYQYPPGYSHHNFPPP 180
              P     +PPP    PPP       PP++PQ  +   P        PPP
Sbjct: 1217 IPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 63/199 (31%), Positives = 73/199 (36%), Gaps = 38/199 (19%)

Query: 46   QPP----VQYQYEPPSAPSTTFSNS---PAPNFLP--------PRPDFVPFPPPMPPSAQ 90
            QPP     ++Q     + S+ F NS   P+P  LP        P    VP PPP  P   
Sbjct: 828  QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT 887

Query: 91   GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPF------ 144
             P  P    P  P      P       PP PPP+P    PP P  P G G  P       
Sbjct: 888  VPTLPSTAIPQPP------PLQGTEMLPPPPPPLPGAGIPPPPPLP-GAGILPLPPLPGA 940

Query: 145  -MMPPPSMPH---PPPPPVMPQQVNYQYP-PGYSHHNFPPPSFNSFQNNPSSFLPSANNS 199
             + PPP +P    PPPPP+    +    P PG      PPP        P   LP A   
Sbjct: 941  GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIP 998

Query: 200  SSPHFRHL---PPYPLPKA 215
              P        PP PLP A
Sbjct: 999  PPPPLPGAGIPPPPPLPGA 1017



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 46/151 (30%), Positives = 56/151 (37%), Gaps = 24/151 (15%)

Query: 14   PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNF-- 71
            PG G P      GA    P   P   R+  P  PP+     PP  P       P P    
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLP---RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181

Query: 72   --LPPRPDF----VPFPPPMPPSAQGPLPPCPIR--PPFPNHQMRHPFPVPPCFPPMPPP 123
              +PP P      +P PPP+P +   P PP P    PP P        P+PP    +PPP
Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP------PLPPPGTGIPPP 1235

Query: 124  MPCPNNPPVPGAPPGQGTFPF-----MMPPP 149
               P + P      G  T P       +PPP
Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 29/117 (24%), Positives = 40/117 (34%), Gaps = 24/117 (20%)

Query: 120 MPPPMPCPNNPPVP-GAPPGQGT------------------FPFMMPPPSMPHPPPPPVM 160
           +PP    P  PP P GA  G  T                       P  S+  PPPPP +
Sbjct: 757 LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816

Query: 161 PQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPS 217
                   P     H+       S +++ SS   ++ N  SP     PP P  ++ S
Sbjct: 817 LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP-----PPLPCTESSS 868


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
            sapiens]
          Length = 1125

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%)

Query: 24   GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81
            G    P+AP+  P       P   PV        AP       +P+   L  RP  +P  
Sbjct: 784  GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 838

Query: 82   -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134
             PP MPP      P  P RP  P+   R P P P  F  MPPP     P P + P   PG
Sbjct: 839  RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 897

Query: 135  APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183
              PG G  P   P           PP  P   P P  PQQ   Q          PPP+  
Sbjct: 898  GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 954

Query: 184  SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243
              Q  P  F     N +   F         +    RRS       D  R+ + +  R   
Sbjct: 955  --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1004

Query: 244  HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299
            +R  DRRE G RSPDR     R+R   +R R  S HR  ER   R+RE  R ++  R
Sbjct: 1005 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1054



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 96/390 (24%), Positives = 144/390 (36%), Gaps = 86/390 (22%)

Query: 43   HPQQPPVQYQYEPPSAPSTTFSNSPAPNF---LPPRPDFVPF------PPPMPPSAQGPL 93
            H   PPV    +PP+   T     P P F   +PP P   PF      P  +PP    P 
Sbjct: 685  HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 742

Query: 94   PPCPIRPPF---PNHQMRHPFP----------------------VPPCFP---PMPPPMP 125
            PP PI PP    P H      P                      VPP  P   P PP   
Sbjct: 743  PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802

Query: 126  CPNNPPVPGAPPGQ------------GTFPFMMP---PPSMPHP--------PPPPVMPQ 162
              +     G  PG             G  P ++P   PP MP P        PP P+ P 
Sbjct: 803  PVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPH 862

Query: 163  QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
             ++   PPG      PPP        P    P       P      P P P  P +R   
Sbjct: 863  MMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGGMPGLGG--PGPGPGGPEDRDGR 918

Query: 223  ERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSD----YDRGRTPSR- 277
            ++       + +  +  + ++ +        + P  ++Q  ++R+D    ++ GR   R 
Sbjct: 919  QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERF 978

Query: 278  -HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREK--------KRARW 328
              RS+    E +RER+ +R++ R  S      ++ +  G RSP R++        +R+  
Sbjct: 979  GRRSFGNRVENDRERYGNRNDDRDNS-----NRDRREWGRRSPDRDRHRDLEERNRRSSG 1033

Query: 329  EEEKDRWSDNQSSGKDKNYTSIKEKEPEET 358
              +++R S ++ S ++K     KEK PE T
Sbjct: 1034 HRDRERDSRDRESRREKEEARGKEK-PEVT 1062



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 70/270 (25%), Positives = 87/270 (32%), Gaps = 29/270 (10%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102
           P QP  Q    PP    T F       F     P+ V        +A     P    PP 
Sbjct: 238 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 297

Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162
           P   +  P    P     PPP         P   PG G    M  P    H       P+
Sbjct: 298 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 344

Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
            +  Q  P   HH  P P             P     + P     PP   P   S +   
Sbjct: 345 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402

Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRS----PDRRRQDS-----RYRSDYD 270
           E L    H  +           +RH S +R+ R RS    P RRR  S     R R    
Sbjct: 403 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS 462

Query: 271 RGRTPSRHRSYERSRERE-RERHRHRDNRR 299
           R R+  R R   RSR +E R+R + R+ R+
Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQ 492



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 48/150 (32%), Positives = 57/150 (38%), Gaps = 44/150 (29%)

Query: 80  PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136
           P P P+P     P+PP P+             P P   PP  +PP  P    PPV GA  
Sbjct: 657 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 696

Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPPSFNSFQNNPS 190
           P   T P  +PPP       P PPPPP +    N  + PPG+     PPP        P 
Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI-----TPPV 751

Query: 191 SFLPSANNSSSPHFRHLPPYPLPKAPSERR 220
           S  P           H PP  +P   S  R
Sbjct: 752 SIPPP----------HTPPISIPNLVSGAR 771



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 46/127 (36%), Positives = 56/127 (44%), Gaps = 20/127 (15%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103
           P++P  +      +  S T   SP P  LP     VP PP +P  A   +PP    P  P
Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 683

Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHP- 154
            HQ   P      PP F P   +PPP   P  PP P  PP    G  P  +PP  +P P 
Sbjct: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP-PG 742

Query: 155 PPPPVMP 161
           PPPP+ P
Sbjct: 743 PPPPITP 749



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 56/210 (26%), Positives = 73/210 (34%), Gaps = 22/210 (10%)

Query: 56  PSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP 115
           P AP+ T   + AP    P P   PF  P     Q         P +  HQ    F  P 
Sbjct: 295 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ---------PAYTQHQNMDQFQ-PR 344

Query: 116 CFPPMPPPMPCPNNPPVPGAPPGQGTFPFM-MPPPSMPH-PPPPPVM-PQQVNYQ----- 167
                  PM      P  G  PG G  P    PP + P  PP PPV  P Q ++Q     
Sbjct: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEP 404

Query: 168 --YPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS--PHFRHLPPYPLPKAPSERRSPE 223
               P         P     + + S    S + S+S  P  R        +    RRS  
Sbjct: 405 LTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRS 464

Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERG 253
           R +    H  R  S  R +R +  +RR++G
Sbjct: 465 RSRDRRRHSPRSRSQERRDREKERERRQKG 494



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73
           PG G P  R G    P  P  +PQ      PQQP  Q Q +PP       S  P P    
Sbjct: 907 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 957

Query: 74  PR 75
           P+
Sbjct: 958 PQ 959


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
            sapiens]
          Length = 1132

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%)

Query: 24   GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81
            G    P+AP+  P       P   PV        AP       +P+   L  RP  +P  
Sbjct: 791  GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 845

Query: 82   -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134
             PP MPP      P  P RP  P+   R P P P  F  MPPP     P P + P   PG
Sbjct: 846  RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 904

Query: 135  APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183
              PG G  P   P           PP  P   P P  PQQ   Q          PPP+  
Sbjct: 905  GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 961

Query: 184  SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243
              Q  P  F     N +   F         +    RRS       D  R+ + +  R   
Sbjct: 962  --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1011

Query: 244  HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299
            +R  DRRE G RSPDR     R+R   +R R  S HR  ER   R+RE  R ++  R
Sbjct: 1012 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1061



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 97/412 (23%), Positives = 147/412 (35%), Gaps = 108/412 (26%)

Query: 43   HPQQPPVQYQYEPPSAPSTTFSNSPAPNF---LPPRPDFVPF------PPPMPPSAQGPL 93
            H   PPV    +PP+   T     P P F   +PP P   PF      P  +PP    P 
Sbjct: 670  HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 727

Query: 94   PPCPIRPPF---PNH----------------------QMRHPFP---------------- 112
            PP PI PP    P H                       + +P P                
Sbjct: 728  PPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSV 787

Query: 113  ------VPPCFP---PMPPPMPCPNNPPVPGAPPGQ------------GTFPFMMP---P 148
                  VPP  P   P PP     +     G  PG             G  P ++P   P
Sbjct: 788  KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 847

Query: 149  PSMPHP--------PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200
            P MP P        PP P+ P  ++   PPG      PPP        P    P      
Sbjct: 848  PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGG 905

Query: 201  SPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRR 260
             P      P P P  P +R   ++       + +  +  + ++ +        + P  ++
Sbjct: 906  MPGLGG--PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 963

Query: 261  QDSRYRSD----YDRGRTPSR--HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRS 314
            Q  ++R+D    ++ GR   R   RS+    E +RER+ +R++ R  S      ++ +  
Sbjct: 964  QPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNS-----NRDRREW 1018

Query: 315  GSRSPSREK--------KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEET 358
            G RSP R++        +R+    +++R S ++ S ++K     KEK PE T
Sbjct: 1019 GRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK-PEVT 1069



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 18/126 (14%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103
           P++P  +      +  S T   SP P  LP     VP PP +P  A   +PP    P  P
Sbjct: 619 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 668

Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHPP 155
            HQ   P      PP F P   +PPP   P  PP P  PP    G  P  +PP  +P  P
Sbjct: 669 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 728

Query: 156 PPPVMP 161
           PPP+ P
Sbjct: 729 PPPITP 734



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 70/270 (25%), Positives = 87/270 (32%), Gaps = 29/270 (10%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102
           P QP  Q    PP    T F       F     P+ V        +A     P    PP 
Sbjct: 223 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 282

Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162
           P   +  P    P     PPP         P   PG G    M  P    H       P+
Sbjct: 283 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 329

Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
            +  Q  P   HH  P P             P     + P     PP   P   S +   
Sbjct: 330 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 387

Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRS----PDRRRQDS-----RYRSDYD 270
           E L    H  +           +RH S +R+ R RS    P RRR  S     R R    
Sbjct: 388 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS 447

Query: 271 RGRTPSRHRSYERSRERE-RERHRHRDNRR 299
           R R+  R R   RSR +E R+R + R+ R+
Sbjct: 448 RSRSRDRRRHSPRSRSQERRDREKERERRQ 477



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 29/110 (26%)

Query: 80  PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136
           P P P+P     P+PP P+             P P   PP  +PP  P    PPV GA  
Sbjct: 642 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 681

Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPP 180
           P   T P  +PPP       P PPPPP +    N  + PPG+     PPP
Sbjct: 682 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPP 731



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 56/210 (26%), Positives = 73/210 (34%), Gaps = 22/210 (10%)

Query: 56  PSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP 115
           P AP+ T   + AP    P P   PF  P     Q         P +  HQ    F  P 
Sbjct: 280 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ---------PAYTQHQNMDQFQ-PR 329

Query: 116 CFPPMPPPMPCPNNPPVPGAPPGQGTFPFM-MPPPSMPH-PPPPPVM-PQQVNYQ----- 167
                  PM      P  G  PG G  P    PP + P  PP PPV  P Q ++Q     
Sbjct: 330 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEP 389

Query: 168 --YPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS--PHFRHLPPYPLPKAPSERRSPE 223
               P         P     + + S    S + S+S  P  R        +    RRS  
Sbjct: 390 LTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRS 449

Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERG 253
           R +    H  R  S  R +R +  +RR++G
Sbjct: 450 RSRDRRRHSPRSRSQERRDREKERERRQKG 479



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73
           PG G P  R G    P  P  +PQ      PQQP  Q Q +PP       S  P P    
Sbjct: 914 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 964

Query: 74  PR 75
           P+
Sbjct: 965 PQ 966


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
            sapiens]
          Length = 1147

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%)

Query: 24   GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81
            G    P+AP+  P       P   PV        AP       +P+   L  RP  +P  
Sbjct: 806  GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 860

Query: 82   -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134
             PP MPP      P  P RP  P+   R P P P  F  MPPP     P P + P   PG
Sbjct: 861  RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 919

Query: 135  APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183
              PG G  P   P           PP  P   P P  PQQ   Q          PPP+  
Sbjct: 920  GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 976

Query: 184  SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243
              Q  P  F     N +   F         +    RRS       D  R+ + +  R   
Sbjct: 977  --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1026

Query: 244  HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299
            +R  DRRE G RSPDR     R+R   +R R  S HR  ER   R+RE  R ++  R
Sbjct: 1027 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1076



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 97/412 (23%), Positives = 147/412 (35%), Gaps = 108/412 (26%)

Query: 43   HPQQPPVQYQYEPPSAPSTTFSNSPAPNF---LPPRPDFVPF------PPPMPPSAQGPL 93
            H   PPV    +PP+   T     P P F   +PP P   PF      P  +PP    P 
Sbjct: 685  HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 742

Query: 94   PPCPIRPPF---PNH----------------------QMRHPFP---------------- 112
            PP PI PP    P H                       + +P P                
Sbjct: 743  PPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSV 802

Query: 113  ------VPPCFP---PMPPPMPCPNNPPVPGAPPGQ------------GTFPFMMP---P 148
                  VPP  P   P PP     +     G  PG             G  P ++P   P
Sbjct: 803  KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 862

Query: 149  PSMPHP--------PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200
            P MP P        PP P+ P  ++   PPG      PPP        P    P      
Sbjct: 863  PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGG 920

Query: 201  SPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRR 260
             P      P P P  P +R   ++       + +  +  + ++ +        + P  ++
Sbjct: 921  MPGLGG--PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 978

Query: 261  QDSRYRSD----YDRGRTPSR--HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRS 314
            Q  ++R+D    ++ GR   R   RS+    E +RER+ +R++ R  S      ++ +  
Sbjct: 979  QPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNS-----NRDRREW 1033

Query: 315  GSRSPSREK--------KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEET 358
            G RSP R++        +R+    +++R S ++ S ++K     KEK PE T
Sbjct: 1034 GRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK-PEVT 1084



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 18/126 (14%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103
           P++P  +      +  S T   SP P  LP     VP PP +P  A   +PP    P  P
Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 683

Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHPP 155
            HQ   P      PP F P   +PPP   P  PP P  PP    G  P  +PP  +P  P
Sbjct: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 743

Query: 156 PPPVMP 161
           PPP+ P
Sbjct: 744 PPPITP 749



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 70/270 (25%), Positives = 87/270 (32%), Gaps = 29/270 (10%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102
           P QP  Q    PP    T F       F     P+ V        +A     P    PP 
Sbjct: 238 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 297

Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162
           P   +  P    P     PPP         P   PG G    M  P    H       P+
Sbjct: 298 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 344

Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
            +  Q  P   HH  P P             P     + P     PP   P   S +   
Sbjct: 345 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402

Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRS----PDRRRQDS-----RYRSDYD 270
           E L    H  +           +RH S +R+ R RS    P RRR  S     R R    
Sbjct: 403 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS 462

Query: 271 RGRTPSRHRSYERSRERE-RERHRHRDNRR 299
           R R+  R R   RSR +E R+R + R+ R+
Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQ 492



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 29/110 (26%)

Query: 80  PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136
           P P P+P     P+PP P+             P P   PP  +PP  P    PPV GA  
Sbjct: 657 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 696

Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPP 180
           P   T P  +PPP       P PPPPP +    N  + PPG+     PPP
Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPP 746



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 56/210 (26%), Positives = 73/210 (34%), Gaps = 22/210 (10%)

Query: 56  PSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP 115
           P AP+ T   + AP    P P   PF  P     Q         P +  HQ    F  P 
Sbjct: 295 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ---------PAYTQHQNMDQFQ-PR 344

Query: 116 CFPPMPPPMPCPNNPPVPGAPPGQGTFPFM-MPPPSMPH-PPPPPVM-PQQVNYQ----- 167
                  PM      P  G  PG G  P    PP + P  PP PPV  P Q ++Q     
Sbjct: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEP 404

Query: 168 --YPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS--PHFRHLPPYPLPKAPSERRSPE 223
               P         P     + + S    S + S+S  P  R        +    RRS  
Sbjct: 405 LTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRS 464

Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERG 253
           R +    H  R  S  R +R +  +RR++G
Sbjct: 465 RSRDRRRHSPRSRSQERRDREKERERRQKG 494



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73
           PG G P  R G    P  P  +PQ      PQQP  Q Q +PP       S  P P    
Sbjct: 929 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 979

Query: 74  PR 75
           P+
Sbjct: 980 PQ 981


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 55/160 (34%), Positives = 63/160 (39%), Gaps = 9/160 (5%)

Query: 36  PQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGP--L 93
           P+   ++ P  PP       P  P   F+  PAP   PP P  +  PPP PP   G    
Sbjct: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPP--PPPPPMIGIPPPPPPVGFGSPGT 346

Query: 94  PPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPH 153
           PP P  P FP H     F  PP  PP PP    P  PP P + P  G  P   PPP    
Sbjct: 347 PPPPSPPSFPPHP---DFAAPPP-PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG- 401

Query: 154 PPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFL 193
           PPPPP          PP  S    P  S  +  +  S  L
Sbjct: 402 PPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLL 441



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 57/181 (31%), Positives = 70/181 (38%), Gaps = 32/181 (17%)

Query: 29  PSAPSFRPQNLR---LLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM 85
           P+  S+   N R   L  P++  V     PP AP       P P F PP     P PPP 
Sbjct: 271 PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPP-----PAPPPP 325

Query: 86  PPSAQG-PLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPF 144
           PP   G P PP P+    P      P P PP FPP P     P  PP             
Sbjct: 326 PPPMIGIPPPPPPVGFGSPGTP---PPPSPPSFPPHPD-FAAPPPPP------------- 368

Query: 145 MMPPPSMPHP--PPPPV-MPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201
             PPP+  +P  PPPP+  P       PP       PPP F      P +  P  ++++ 
Sbjct: 369 --PPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQP-AIPPPLSDTTK 425

Query: 202 P 202
           P
Sbjct: 426 P 426



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 48/167 (28%), Positives = 56/167 (33%), Gaps = 34/167 (20%)

Query: 73  PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMR----------------HPFPVPPC 116
           PP P       P P  ++  LPP P    +P    R                HP P PP 
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306

Query: 117 FPP-------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYP 169
             P        PPP P P  PP+ G PP     P     P  P PP PP  P   ++  P
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP--PVGFGSPGTPPPPSPPSFPPHPDFAAP 364

Query: 170 PGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216
           P       PPP    +   P   L      + P     PP P P  P
Sbjct: 365 PPP-----PPPPAADYPTLPPPPLSQPTGGAPPP----PPPPPPPGP 402



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 50/147 (34%), Positives = 59/147 (40%), Gaps = 18/147 (12%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73
           P  G P G     A P AP   P  +  + P  PPV +       P +  S  P P+F  
Sbjct: 304 PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA 363

Query: 74  PRPDFVPFPPPMPPSAQGP-LPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132
           P       PPP PP+A  P LPP P+  P            PP  PP PPP P P  PP 
Sbjct: 364 PP------PPPPPPAADYPTLPPPPLSQPTGG--------APP--PPPPPPPPGPPPPPF 407

Query: 133 PGAPPGQGTFPFMMPPPSMPHPPPPPV 159
            GA  GQ   P  +   + P    P V
Sbjct: 408 TGA-DGQPAIPPPLSDTTKPKSSLPAV 433


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 67/213 (31%), Positives = 79/213 (37%), Gaps = 69/213 (32%)

Query: 53  YEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP-----SAQGPLPPCPIRPPFPN--- 104
           ++PP+ P    S S  P  L P    VP PPP PP     SA   L P P  P  P    
Sbjct: 684 FKPPTPPVMQ-SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA 742

Query: 105 -------HQMRHPFPVPPCFPPMPPPMPCPNNP--------------------------- 130
                  HQ++H   V P  PP PPP+P P  P                           
Sbjct: 743 PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA 802

Query: 131 ---PVPGAPPG--QGTFPFMMPPPSMPHPP---PPPVMPQQVNYQYPPGYSHHNFPPPSF 182
              P P  PP   Q  FP    PPS P PP   PPP +P+Q ++           PPPS 
Sbjct: 803 PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK--------PPPS- 853

Query: 183 NSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKA 215
                 P S +PS     +  F   PP P P A
Sbjct: 854 ------PLSPVPSVVKQIASQF---PPPPTPPA 877



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 67/210 (31%), Positives = 78/210 (37%), Gaps = 43/210 (20%)

Query: 44   PQQPPVQYQYEPPSAPST-TFSNSPAPNFLPPRPDFVPF------PPPMPPSAQG-PLPP 95
            P  PPV     PP+ P   +F   P P+ L P P  V        PPP PP+ +  PL P
Sbjct: 828  PPTPPVPVP--PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885

Query: 96   CP--IRPPFPNHQMRHP-------------FPVPP-----CFPPMPPPMPCPNNPPVPGA 135
             P  + P  P      P             FP PP      FPP PPP P P  PP P  
Sbjct: 886  VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP-PPPSPVPAPPPPP-- 942

Query: 136  PPGQGTFPFMMPPP-------SMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNN 188
            PP     P     P       S P    PP  PQ+ +       + H  P P   S  + 
Sbjct: 943  PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH--PEPKRPSVDSL 1000

Query: 189  PSSFLPSANNSSSPHFRHLPPYPLPKAPSE 218
             S F P A  S SP    LPP   P  P +
Sbjct: 1001 VSKFTPPA-ESGSPSKETLPPPAAPPKPGK 1029



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 67/217 (30%), Positives = 83/217 (38%), Gaps = 41/217 (18%)

Query: 29  PSAPSFR--PQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM- 85
           PS P F   P  L++   Q      Q  PP+ P      +P P   PP+P  V  P P  
Sbjct: 735 PSLPQFSAPPPPLKIHQVQHIT---QVAPPTPPPPPPIPAPLPPQAPPKP-LVTIPAPTS 790

Query: 86  ------------PPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFP-PMPPP-MP-----C 126
                       PP+   P+PP   +P FP   +    P PP  P P+PPP +P     C
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP---PSPPTPPVPVPPPTLPKQQSFC 847

Query: 127 PNNPPVPGAPPGQ------GTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGY-SHHNFPP 179
              PP P +P           FP    PP+M   P  PV P  V  Q PP   +   + P
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV-PANVAPQSPPAVKAKPKWQP 906

Query: 180 PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216
            S       PS   P     SS  F   PP P+P  P
Sbjct: 907 SSIPV----PSPDFPPPPPESSLVFPPPPPSPVPAPP 939



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 58/189 (30%), Positives = 71/189 (37%), Gaps = 13/189 (6%)

Query: 55  PPSAPSTTFSNSPAPNFLPPRPDF--VPFPPPMPPSAQG---PLPPCPIRP-PFPNHQMR 108
           PP  P+      PA +++PP P    VP PPP  P  Q      PP P+ P P    Q+ 
Sbjct: 808 PPVPPAKKQPAFPA-SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866

Query: 109 HPFPVPPCFPPMP--PPMPCPNNPPVPGAPPGQGTFPFMMP---PPSMPHPPPPPVMPQQ 163
             FP PP  P M   P  P P N   P +PP     P   P   P   P  PPPP     
Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANV-APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSL 925

Query: 164 VNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPE 223
           V    PP       PPP   +      S  P    S +       P P P+  S  +S  
Sbjct: 926 VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985

Query: 224 RLKHYDDHR 232
             +H +  R
Sbjct: 986 GAEHPEPKR 994



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 54/200 (27%), Positives = 64/200 (32%), Gaps = 42/200 (21%)

Query: 52  QYEPPSAPSTTFSNSPAPNFLPP---RPDFV----------PFPPPMPPSAQGPLPPCPI 98
           Q E  S       N P  + +PP   +P  V          P PPP PP    P PP P 
Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP 645

Query: 99  RPPFPNHQMRHPFPVPPCF---------------------PPMPPPMPCPNNPPVPGAPP 137
            PP P+          P F                     PP PP M   +  P    PP
Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705

Query: 138 GQGTFPFMMPPPSMPHPPPPP--VMPQQVNYQYPPGYSHHNFPPPSFNSFQ-NNPSSFLP 194
                  ++PPP  P PPP P   M Q       P     + PPP     Q  + +   P
Sbjct: 706 NG-----VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760

Query: 195 SANNSSSPHFRHLPPYPLPK 214
                  P    LPP   PK
Sbjct: 761 PTPPPPPPIPAPLPPQAPPK 780



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 48/161 (29%), Positives = 57/161 (35%), Gaps = 36/161 (22%)

Query: 92  PLPPCP-IRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVP--GAPPGQGTFPFMMPP 148
           PL P P I  P+   Q   P P PP  PP PPP P P  PP+P   AP      P  +  
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667

Query: 149 PSMPH-------------PPPPPVMPQQ---------VNYQYPPGYSHHNFPPPSFNSFQ 186
            ++               PP PPVM  Q          N   PP       P P     Q
Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727

Query: 187 NNPSSFLPSANNSSSP-------HFRHL----PPYPLPKAP 216
             P+   PS    S+P         +H+    PP P P  P
Sbjct: 728 LKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 52/207 (25%), Positives = 62/207 (29%), Gaps = 78/207 (37%)

Query: 29   PSAPSFRPQNLRLLH----PQQPPV---QYQYEPPSAPSTTFSNSPAPN-----FLPPRP 76
            P+ P+   Q L+ +     PQ PP    + +++P S P  +    P P      F PP P
Sbjct: 873  PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932

Query: 77   DFVPFPPPMPPSAQGPLP---------------PCPIRPPFPNHQMR----------HPF 111
              VP PPP PP    P P               P   +PP P  Q            HP 
Sbjct: 933  SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP-PTPQRNSSIKSSSGAEHPE 991

Query: 112  PVPPCF--------PPMPPPMPCPNNPPVPGAPPGQGTF--------------------- 142
            P  P          PP     P     P P APP  G                       
Sbjct: 992  PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051

Query: 143  -----------PFMMPPPSMPHPPPPP 158
                        F  PP     PPPPP
Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPP 1078



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 23/138 (16%)

Query: 98  IRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPP 157
           + P  P  ++  P+      PP+PPP P P  PP P  PP         P PS   P   
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP-------PLPSQSAPSAG 658

Query: 158 PVMPQQVNY------QYPPGYSHHNFPPPS---FNSFQNNPSSFLPSANNSSSPHFRHLP 208
              P  V Y      Q    +S   F PP+     S    P   +P   N   P     P
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP--NGVVP-----P 711

Query: 209 PYPLPKAPSERRSPERLK 226
           P P P  P+   +  +LK
Sbjct: 712 PPPPPPPPTPGSAMAQLK 729


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 60/155 (38%), Positives = 77/155 (49%), Gaps = 20/155 (12%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR 273
           ++PS++RS    K  DD R R     R        RRER RS D+RR  SR     DR R
Sbjct: 25  RSPSDKRS----KRGDDRRSRSRDRDR--------RRERSRSRDKRRSRSR-----DRKR 67

Query: 274 TPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKD 333
              R RS ER R RER R R RD RRS S  R  +      G++S   E  R+R +E+ D
Sbjct: 68  L-RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTE-NRSRSKEKTD 125

Query: 334 RWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368
               ++   KDK+     EKE +    D+N+ EEE
Sbjct: 126 GGESSKEKKKDKD-DKEDEKEKDAGNFDQNKLEEE 159



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 15/146 (10%)

Query: 239 GRGERHRSLDRRERGRSPDRRRQDS-----RYRSDYDRGRTPSRHRSYERSRERERERHR 293
           GR  RH       RGRS  R R  S       R D  R R+  R R  ERSR R++ R R
Sbjct: 2   GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61

Query: 294 HRDN---RRSPSLERSYKKEYKRSGSRSPSREKKRARWEE-------EKDRWSDNQSSGK 343
            RD    RRS S ER   +E +RS SR   R + R+R           K + ++N+S  K
Sbjct: 62  SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121

Query: 344 DKNYTSIKEKEPEETMPDKNEEEEEE 369
           +K       KE ++   DK +E+E++
Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEKEKD 147



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 16/171 (9%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRE-RGRSPDRRRQDSRYRSDYDRG 272
           K  S  R  +RL+     R RD S  R  R RS DRR  R RS  RR + S   +   + 
Sbjct: 57  KRRSRSRDRKRLRR-SRSRERDRSRER-RRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKT 114

Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEK 332
              SR +      E  +E+ + +D++     + +   +  +       R+++  +W EE+
Sbjct: 115 ENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174

Query: 333 DRWSDNQSSGKDKNYTSIK-------------EKEPEETMPDKNEEEEEEL 370
            + +        K    +K             E +P E   + NE E EEL
Sbjct: 175 RKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEEL 225



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 49/218 (22%), Positives = 83/218 (38%), Gaps = 24/218 (11%)

Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGS--------RSPSREKKRARW 328
           R   + R R   R R   R   RSPS +RS + + +RS S        RS SR+K+R+R 
Sbjct: 3   RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62

Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSD 388
            + K R   ++S  +D++    + +  +                    +   +EN   S 
Sbjct: 63  RDRK-RLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121

Query: 389 PMDQVGDSTVVGTSRLRDLYD------------KFEEELGSRQEKAKAARPPWEPPKTKL 436
                G+S+        D  D            K EEE+  R+E+ +  R   E  + K 
Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWR---EEQRKKA 178

Query: 437 DEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRK 474
            E++    +   E  +    S   D +  D  AE +++
Sbjct: 179 MENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKE 216


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 62/187 (33%), Positives = 78/187 (41%), Gaps = 24/187 (12%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPA----PNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR 99
           P  PPVQ  + PP++P  + S +P     P+   P     P PP  PP +    PP    
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727

Query: 100 PPFPNHQMRHPFPVPPCFPPMPPPM-PCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--- 155
           PP     ++ P P PP  PPM P   P P  PP+  APP Q       PP S+P  P   
Sbjct: 728 PPLAAPPLQVP-PSPPASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMSPLAK 783

Query: 156 PPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKA 215
           PPP  P  +     P       PP SF       + F PSA+   SP        P P+A
Sbjct: 784 PPPQAPPAL---ATPPLQALPSPPASF----PGQAPFSPSASLPMSP-----LATPPPQA 831

Query: 216 PSERRSP 222
           P    +P
Sbjct: 832 PPVLAAP 838



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 69/247 (27%), Positives = 86/247 (34%), Gaps = 32/247 (12%)

Query: 29  PSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR-------PDFVPF 81
           P +PS  P +        PP+Q    PP++P  + S +P P   PP        P   P 
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 82  PPPMPPSAQGP--------LPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVP 133
            PPM PSA  P         PP  + P  P      P   PP  P  PP +  P    +P
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP--PQAPPALATPPLQALP 801

Query: 134 GAP---PGQGTF----PFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQ 186
             P   PGQ  F       M P + P P  PPV+   +  Q PP        PP+  + Q
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPS-------PPASPTLQ 853

Query: 187 NNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRS 246
                  P  + S S     L   P P  P  R     L   D   H   +    E  R 
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913

Query: 247 LDRRERG 253
            D    G
Sbjct: 914 YDSGPEG 920



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 64/206 (31%), Positives = 76/206 (36%), Gaps = 32/206 (15%)

Query: 47  PPVQYQYEPPSAPSTTFSNSP---APNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF- 102
           PP+Q    PP++P  +   +P   APN L       PF PP  P  Q P  P P  PP  
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVS 686

Query: 103 ---------PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP------ 147
                    P      P  VPP  PP  PPM  P+  P P APP     P  +P      
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPS-PPASPPM-SPSATPPPQAPPPLAAPPLQVPPSPPAS 744

Query: 148 PPSMPHPPPPPVMPQQV---NYQYPPG------YSHHNFPPPSF-NSFQNNPSSFLPSAN 197
           PP  P   PPP +P  +     Q PP        S    PPP    +    P   LPS  
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804

Query: 198 NSSSPHFRHLPPYPLPKAPSERRSPE 223
            S        P   LP +P     P+
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQ 830



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 58/189 (30%), Positives = 65/189 (34%), Gaps = 56/189 (29%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQP-PVQYQYEPPSAPSTTFSNSPAPNFL 72
           P R  P  RG     P AP+         HP QP P   Q   P            P   
Sbjct: 252 PARSGPSARG----TPRAPA---------HPSQPKPKGLQALRP------------PQVT 286

Query: 73  PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP--------VPPCFPPMPP-P 123
           PPR D  P        A GPL   P+  P P+     P P        +P   PP PP  
Sbjct: 287 PPRKDAAP--------ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338

Query: 124 MPCPNNPPVPGAPPGQGTFPF------MMPPPSMPHPP--PPPVMPQQVNYQYPPGYSHH 175
            P P  PP P APP   T P          PPSM  PP   PP +        PP    H
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL-----QTIPPIQVPH 393

Query: 176 NFPPPSFNS 184
           +   PS  +
Sbjct: 394 SLTSPSLQA 402



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 62/217 (28%), Positives = 75/217 (34%), Gaps = 47/217 (21%)

Query: 43  HPQQPPVQYQYEPP-----SAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPL---- 93
           H  Q P+     PP     S    +    PA    PP  +     PP   +A  PL    
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557

Query: 94  ---PPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT-----FPFM 145
              PPCP   P P      P   PP   P     P P  PP   +PP QG       P  
Sbjct: 558 LETPPCPA--PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615

Query: 146 MPPPSMPH----------PPP---PPVMPQQV-NYQYPPGYSHHNF-----PPPS----- 181
            PPP  P           P P   PP+ P    + Q P   + H       PPPS     
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675

Query: 182 -FNSFQNNPSSFLPSAN-NSSSPHFRHLPPYPLPKAP 216
            F+   + P S  PSA   S +P     PP  +P +P
Sbjct: 676 PFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSP 710



 Score = 39.7 bits (91), Expect = 0.020
 Identities = 62/253 (24%), Positives = 79/253 (31%), Gaps = 65/253 (25%)

Query: 29  PSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR---PDFVPFPP-P 84
           PS P   P  L    P  PP       PS P+T  S +P     PP    P     PP  
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTL--PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390

Query: 85  MPPSAQGP---LPPCPIRPPF---------PNHQMRHPF-------------------PV 113
           +P S   P    PP P+             P  Q  H F                     
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450

Query: 114 PPCFPPMPPPMPCPNNPPV-----PGAPPGQGTF---PFMMPPPSMPHPPPPPVMPQQVN 165
           PP  PP+  P+  P +PP+     P   P        P         H P  P+     +
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS----S 506

Query: 166 YQYPPGYSHHNFPPPSFNS---------FQNNPSSFLPSANNSS----SPHFRHLP---P 209
              PP  +  +  PPS  +          +N PS   P    +S    +PH    P   P
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566

Query: 210 YPLPKAPSERRSP 222
            PL   PS   +P
Sbjct: 567 CPLQAPPSPLTTP 579



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 37/198 (18%)

Query: 31  APSFRPQNLRLLHPQQPPVQYQYEPPSAPS--TTFSNSPAPNFLPPRPDFVPFPPPMPPS 88
           APS RP+         PP +   +  S+ S  +T   SPA    P     +  P     S
Sbjct: 193 APSARPR---------PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243

Query: 89  AQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPP 148
           +       P+  P  +       P  P  P  P P       P    PP +   P + P 
Sbjct: 244 SSAT----PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299

Query: 149 PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLP 208
            S P   P            P G      PPP      +N ++ LP+    S P      
Sbjct: 300 SSSPLATPS-----------PSGTKARPVPPP------DNAATPLPATLPPSPP-----L 337

Query: 209 PYPLPKAPSERRSPERLK 226
             PLP AP    +P  L+
Sbjct: 338 ATPLPLAPPSPSAPPSLQ 355


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 53/161 (32%), Positives = 78/161 (48%), Gaps = 18/161 (11%)

Query: 217 SERRSPERLKHYDDHRHRDHSHGRG--ERHRSLDRR-----ERGRSPDRRRQDSRYRSDY 269
           +  R  ER K  +  R RD    R   ER R  DR+     ER R  +R+R+  R R + 
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER-ER 309

Query: 270 DRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSRE-KKRARW 328
           +R R   R R  ER RERER+R   RD  +    +R  + E  R  +R   RE +++A  
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369

Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
           E E++R  D QS+         +E+E  E   D++ ++E E
Sbjct: 370 ERERERERDRQSA---------REREERERDRDRDRQKERE 401



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 61/250 (24%), Positives = 108/250 (43%), Gaps = 27/250 (10%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR 273
           + P  + SP R              G G+ H+  D  +R R+  + R+  R +   +R  
Sbjct: 29  RRPGSQESPRR-------------RGLGQAHKDADGDDRERNRQKERERRREKRQTERET 75

Query: 274 TPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRAR-WEEEK 332
              R R  E+ R R+R+RHR R   R    ER   +E  R   +  +R+K+R R  E E 
Sbjct: 76  DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135

Query: 333 DRWSDNQSSG---KDKNYTSIKEKEPE-----ETMPDKNEEEEEELLKPVWIRCTHSENY 384
           +R  D Q+ G   +++   + KE+E +     +   ++N ++E E  K    R    E  
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN---RQERRERE 192

Query: 385 YSSDPMDQVGD-STVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 443
              +  ++  D  +  G  R R+   + E E   + ++ +  +   E  + K   + E +
Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK-QAERERA 251

Query: 444 SESECESDED 453
           SE E E D++
Sbjct: 252 SERETERDKE 261



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 60/239 (25%), Positives = 97/239 (40%), Gaps = 35/239 (14%)

Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDR---RERGRSPDRRRQDSRYRSDYDRGRT 274
           ERR  +R    +  R R+    + +RHR  DR   R+R R  +R RQ  R R        
Sbjct: 63  ERRREKRQTERETDRKRERRREK-DRHRKRDRHRERQRDREKERERQTDRERD------- 114

Query: 275 PSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDR 334
             R R  ER+R++ERER   R+  R    +   ++E +R       RE++  R  + +  
Sbjct: 115 --RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172

Query: 335 WSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVG 394
            +  +   ++KN    +E+E +    +K E+   E  +    R    E    ++   Q  
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE---RERERETETETERKRQ-- 227

Query: 395 DSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDED 453
                 T R RD   K E E   + E+ +A+           + + E   E E E D D
Sbjct: 228 ------TDRERDRQRKTEREREKQAERERAS-----------ERETERDKERERERDRD 269



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 1/153 (0%)

Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRS-DYDRGRTPS 276
           +RR  ER +  D  R R     R    +   +RER R  +R R+  R R  + +R R   
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332

Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWS 336
             R  E+ RER+R+R    D  R+    R  +++ +R   R   R+++ AR  EE++R  
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392

Query: 337 DNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
           D     + +  T        ET   +  E++ E
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRE 425



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 15/159 (9%)

Query: 223 ERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRGRTPSRHRSY 281
           ER +  D  + R+    R ER R  +R R++ R  ++ RQ+ R R         +  R  
Sbjct: 148 ERERQRDAEKERERQTDR-ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206

Query: 282 ERSRERERERH------------RHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWE 329
           ER RERERER             R RD +R    ER  + E +R+  R   R+K+R R E
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER-E 265

Query: 330 EEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368
            ++DR  D +   +++     +++  E     + + E +
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 50/166 (30%), Positives = 73/166 (43%), Gaps = 20/166 (12%)

Query: 223 ERLKHYDDHRHRDHSHGR-----GERHRSLDR-----RERGRSPDRRRQDSRYRSDYDRG 272
           ER +  D  R R     R      ER R+ +R     +ER R  DR R   R + + +R 
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282

Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEE-- 330
               R R  ER RE ER+R R R+  R     R  ++E +R   R   RE +R R +E  
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342

Query: 331 -------EKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
                  E DR   N+ +G++    + +E+E E     ++  E EE
Sbjct: 343 RKRKRQTEMDR-ERNRQTGREGRRQAERERERERERDRQSAREREE 387



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 12/143 (8%)

Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSR 277
           + R  +R +  +  R R+   GR  R ++   RER R  +R RQ +R R + +R R    
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQA--ERERERERERDRQSAREREERERDR---- 392

Query: 278 HRSYERSRERERERHRHRDNRRSPSLERSYKK--EYKRSGSRSPSREKKRARWEEEKDRW 335
               +R +ERER+  + RD +R    +R  +K  E +R   R   REK++ R E +++R 
Sbjct: 393 --DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR-ERDRERQ 449

Query: 336 SDNQSSGKDKNYTSIKEKEPEET 358
           +D Q +G+ +  +++    P  T
Sbjct: 450 TDRQ-AGRQRKRSTLYVNPPPRT 471



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 66/255 (25%), Positives = 97/255 (38%), Gaps = 23/255 (9%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR 273
           K   ERR  ER +  ++     HS    ER R    RE     +R+RQ  R R   DR R
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERE---RETETETERKRQTDRER---DRQR 236

Query: 274 TPSRHRSYERSRERERERHRHRDNRRSPSLERS-----YKKEYKRSGSRSPSREKKRARW 328
              R R  +  RER  ER   RD  R    +R       +KE +R   R   R  +R R 
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296

Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSD 388
            E K      +   +++N    +E+E E     + E E +   +    R   +E      
Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE------ 350

Query: 389 PMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESEC 448
            MD+  +    G    R    + E E   R+   ++AR   E  + + D D +   E + 
Sbjct: 351 -MDRERNRQ-TGREGRRQAERERERE---RERDRQSAREREERERDR-DRDRQKERERQT 404

Query: 449 ESDEDSTCSSSSDSE 463
           E D D    +    E
Sbjct: 405 EKDRDGQRETEKQRE 419



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 5/151 (3%)

Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDRR-ERGRSPDRRRQDSRYRSDYDRGRTPSRH 278
           R  ER +  +    R+    R + +++ DR  ERGR  +R R+     ++ +R R   R 
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE---TETERKRQTDRE 231

Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRS-PSREKKRARWEEEKDRWSD 337
           R  +R  ERERE+   R+       ER  ++E +R   R    R+K+R R  + K +   
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291

Query: 338 NQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368
            +    ++     +E+E E     K E E E
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERE 322



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 48/154 (31%), Positives = 70/154 (45%), Gaps = 18/154 (11%)

Query: 220 RSPERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYR-----SDYDRG 272
           R  ER +     R R+    R  ER R  +R RER R  +R R+  R R     ++ DR 
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354

Query: 273 RTPSRHRSYERSRERERERHRHRDNR---------RSPSLERSYKKEYKRSGSRSPSREK 323
           R     R   R  ERERER R RD +         R    +R  ++E +    R   RE 
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414

Query: 324 KRARWEEEKDRWSD-NQSSGKDKNYTSIKEKEPE 356
           ++ R E EKDR S+  +  G+++     +E++ E
Sbjct: 415 EKQR-EREKDRESERGRERGREREKQKGRERDRE 447



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 259 RRQDSRYRSDYDRGRTPSRHRSYERSRERERERHR-HRDNRRSPSLERSYKKEYKRSGSR 317
           RR+     S   RG   +   +    RER R++ R  R  +R    E   K+E +R   R
Sbjct: 28  RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87

Query: 318 SPSREKKRARW---EEEKDRWSD---NQSSGKDKNYTSIKEKEPE 356
              R++ R R    E+E++R +D   ++   K++N    +E+E E
Sbjct: 88  HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE 132


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 76/282 (26%), Positives = 123/282 (43%), Gaps = 37/282 (13%)

Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRG 272
           K   ER+  E+ +  +  R R+    R ER R  +R RER +  +R R+  R R D DR 
Sbjct: 297 KKEKERQEIEKERR-ERERERERERERREREREREREREREKEKERERERERDR-DRDRT 354

Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEK 332
           +   R R  ER R+R+RER   R+  RS S E+S  +E +R   R   RE++R R E E+
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER-ERER 413

Query: 333 DRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELL--KPVWIRCTHSENYYSSDPM 390
           +R  + +           +E+E E+      EE+EE+    + +  +    E  Y     
Sbjct: 414 ERERERE-----------REREREKDKKRDREEDEEDAYERRKLERKLREKEAAY----Q 458

Query: 391 DQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAAR----------PPWEPPKTKLDEDL 440
           +++ +  +    + R+   + E E   R+E AK A+             + PK      L
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518

Query: 441 ES---SSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPD 479
           +      E E E+DE        + E  + I +    + HPD
Sbjct: 519 QKRLRDREKEMEADER---DRKREKEELEEIRQRLLAEGHPD 557



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 13/161 (8%)

Query: 221 SPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRS 280
           S E  K  D H+  +   G+ E+ R    +ER R  +R R+  R R + +R R   R R 
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERERERERRERERERERERERE 336

Query: 281 YERSRERE----------RERHRHRDNR--RSPSLERSYKKEYKRSGSRSPSREKKRARW 328
            E+ RERE          +ER R RD    R    ERS  +   RS SR  SR+++R R 
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396

Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
            E +      +   +++     +E+E E     K + EE+E
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDE 437



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 8/215 (3%)

Query: 242 ERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERER-HRHRDNRRS 300
           E  R L  RE  +  D  ++    +   ++ R        ER RERERER  R R+  R 
Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330

Query: 301 PSLERSYKKEYKRSGSRSPSREKKRAR---WEEEKDRWSDNQ-SSGKDKNYTSIKEKEPE 356
              ER  +KE +R   R   R++ + R    + E+DR  D + SS ++K+ +  +EK  +
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390

Query: 357 ETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYD--KFEEE 414
                + E E E   +    R    E     +  ++  D          D Y+  K E +
Sbjct: 391 RERERERERERERERERERERERERERERERE-REREKDKKRDREEDEEDAYERRKLERK 449

Query: 415 LGSRQEKAKAARPPWEPPKTKLDEDLESSSESECE 449
           L  ++   +     WE  + K   + E  +E E E
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 10/159 (6%)

Query: 223 ERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRT-PSRHRS- 280
           ERLK+++    +       E  R  +RR       +R ++  +  DYD  R  P  +R  
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE--FLEDYDDDRDDPKYYRGS 516

Query: 281 --YERSRERERERHR-HRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRW-- 335
              +R R+RE+E     RD +R        ++     G   P  E +R   E E+ R   
Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576

Query: 336 -SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKP 373
                 S +++     KE++ EE M ++ E E++  LKP
Sbjct: 577 IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKP 615



 Score = 37.4 bits (85), Expect = 0.097
 Identities = 37/174 (21%), Positives = 66/174 (37%), Gaps = 27/174 (15%)

Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHR 279
           R  ER +  D  R R+         R L+R+ R +         R ++   R R  +R  
Sbjct: 419 REREREREKDKKRDREEDEEDAYERRKLERKLREKEA---AYQERLKNWEIRERKKTREY 475

Query: 280 SYERSRERERERHRHRDNRRSPSL------ERSYKKEYKRSGSRSPSREKKRARWEEEKD 333
             E  RE ER R   ++ +R          +R   K Y+ S  +   R++++    +E+D
Sbjct: 476 EKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERD 535

Query: 334 R------------------WSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
           R                    D  +  +     + + ++P+     ++EEEEEE
Sbjct: 536 RKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 102 FPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMP 161
           FP H  R P  +P   P +PPP      PPVP   P       M+P P     P P V+ 
Sbjct: 3   FPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTP-------MIPVPMSIMAPAPTVLV 55

Query: 162 QQVN 165
             V+
Sbjct: 56  PTVS 59



 Score = 31.6 bits (70), Expect = 5.3
 Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 6/46 (13%)

Query: 81  FPPPM--PPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM 124
           FPP +  PP     LPP    P FP      P PVPP  P +P PM
Sbjct: 3   FPPHLNRPPMGIPALPPGIPPPQFPG----FPPPVPPGTPMIPVPM 44


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 83/301 (27%), Positives = 111/301 (36%), Gaps = 52/301 (17%)

Query: 56  PSAPST-TFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114
           PS P+T  F   P P   PP P  +P PP +PP    P  P P +PP   + +      P
Sbjct: 548 PSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFP-PGQPPPAGYSV-----PP 601

Query: 115 PCFPPMPPPMPCP-----------NNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQ 163
           P FPP P  +  P           N  P   APP      F      +      P     
Sbjct: 602 PGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPP-LSREEFYREQRRLKEESKSPYSGS- 659

Query: 164 VNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPE 223
                   YS  ++      S      S+  S + S S  +   PPYP       RR   
Sbjct: 660 -------SYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYP-------RRGRG 705

Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYD-RGRTPSRHRSYE 282
           + ++Y   R R  SHG    HRS     R RSP  RR  SR RS    RG++P++    +
Sbjct: 706 KSRNY---RSRSRSHG---YHRS-----RSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQ 754

Query: 283 RSRERERERHRHRDNRRSPSLERSYKKEYKRS-GSRSPSREKKRARWEEEKDRWSDNQSS 341
              ERE     + +  R        K  Y RS   R P  +++   WE +   W +    
Sbjct: 755 GETERE-----YFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYK 809

Query: 342 G 342
           G
Sbjct: 810 G 810



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 78/355 (21%), Positives = 130/355 (36%), Gaps = 49/355 (13%)

Query: 167  QYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFR-HLPPYPLPKAPSER----RS 221
            +Y  GY+    P PS N    +P  FLP  N  +SP  R     Y   ++   R      
Sbjct: 806  KYYKGYAAGAQPRPSANRENFSPERFLP-LNIRNSPFTRGRREDYVGGQSHRSRNIGSNY 864

Query: 222  PERLKHYDDHRHRDHS------------HGRGERHRSLDRRERG---------------- 253
            PE+L   D H  +D++             G+G +H+   +R +G                
Sbjct: 865  PEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 924

Query: 254  --RSP---DRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYK 308
              R P   +  + DS +        TP R    +      +         R     +  K
Sbjct: 925  KSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984

Query: 309  KEYKRSGSRSPSREK--KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEE 366
             + K  GS    +E   K A+  +EK    D +     ++   IK K  EET    N + 
Sbjct: 985  TKRKNDGSAVSKKENIVKPAKGPQEK---VDGERERSPRSEPPIK-KAKEETPKTDNTKS 1040

Query: 367  EEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDK--FEEELGSRQEKAKA 424
                 K   I  T  + +  S    Q  ++  V   +++  Y K    E+L +++EKAK 
Sbjct: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQ--ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKK 1098

Query: 425  ARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPD 479
                 +P   K ++    + E   + D +S+    S  EV +++    ++K  PD
Sbjct: 1099 PNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD 1153



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 14/71 (19%)

Query: 146 MPPPSMPHPPPPPVMPQQV---------NYQYP---PGYSHHNFPPPSFNSFQNNPSSFL 193
           +PPP  P PPP P++ + +           Q P   P  S    P PS +S  +N SS  
Sbjct: 336 LPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLA 395

Query: 194 P--SANNSSSP 202
           P  S N SS+P
Sbjct: 396 PPVSGNPSSAP 406



 Score = 35.0 bits (79), Expect = 0.48
 Identities = 43/216 (19%), Positives = 84/216 (38%), Gaps = 25/216 (11%)

Query: 195  SANNSSSPHFRHLPPYPLPKAPSERRSPER--LKHYDDHRHRDHSHGRGERHRSLDRRER 252
            S+N   +P+      Y   +  S +R  E+  L    D   R+     G++++  + R+ 
Sbjct: 1428 SSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDL 1487

Query: 253  GR-----------SPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERH--RHRDNRR 299
             +           SP R R+   +++ YD  R     +S +++  ++RE+H    R+N+ 
Sbjct: 1488 PKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKE 1547

Query: 300  SPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETM 359
            S   +  Y      +       EK++   + +K               +S   +E +E  
Sbjct: 1548 SSGNKLLYILNPPET-----QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAA 1602

Query: 360  --PDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQV 393
              PD NE + E     V ++   S    S D  D++
Sbjct: 1603 FEPDYNESDSE---SNVSVKEEESSGNISKDLKDKI 1635



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 4/70 (5%)

Query: 29  PSAPSFRPQNLRLLHP-QQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM-- 85
           P  P  RP   R L P  + P+  Q +P   P T+ S  PAP+      +     PP+  
Sbjct: 341 PPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSG 400

Query: 86  -PPSAQGPLP 94
            P SA  P+P
Sbjct: 401 NPSSAPAPVP 410



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 16/82 (19%), Positives = 36/82 (43%)

Query: 252  RGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEY 311
            R  SP   +  S   S        S+ +  ++ +++ ++  +H+ +++    E   +K  
Sbjct: 1668 RSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQ 1727

Query: 312  KRSGSRSPSREKKRARWEEEKD 333
            K    +  S++ K    E+EKD
Sbjct: 1728 KHKHKKKKSKKNKDKEKEKEKD 1749



 Score = 31.6 bits (70), Expect = 5.3
 Identities = 23/117 (19%), Positives = 46/117 (39%), Gaps = 2/117 (1%)

Query: 255  SPDRRRQDSR--YRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYK 312
            +P++R+  ++    S+ DR       +S  +S +  R   +H   R S + + +  ++ K
Sbjct: 1381 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1440

Query: 313  RSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
                       KR   + E  R  D+ S  KD       +   E  +P K   + ++
Sbjct: 1441 TDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK 1497


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%)

Query: 28  RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87
           RP +P+     +  + P  PP      PP  PS   ++S   +     P  VP PPP P 
Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 88  SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146
           +A Q P  P P  P      + HP P     PP+ PP+  P +PPV  A P   T P   
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414

Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202
            P      +P PPPPP +P       PPG    +  P +  +  + PS   P+ + +  P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465

Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232
           H   +PP P   +  A   +R P  L    D R
Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%)

Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133
           V P  PP PPPM                                       P P  PP+P
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183
            A         M   PPP +P PPPPP        V P     Q  PG  H   PP +  
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392

Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
             Q +P    P A   ++P    +P +PLP+   +   P
Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%)

Query: 28  RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87
           RP +P+     +  + P  PP      PP  PS   ++S   +     P  VP PPP P 
Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 88  SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146
           +A Q P  P P  P      + HP P     PP+ PP+  P +PPV  A P   T P   
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414

Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202
            P      +P PPPPP +P       PPG    +  P +  +  + PS   P+ + +  P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465

Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232
           H   +PP P   +  A   +R P  L    D R
Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%)

Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133
           V P  PP PPPM                                       P P  PP+P
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183
            A         M   PPP +P PPPPP        V P     Q  PG  H   PP +  
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392

Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
             Q +P    P A   ++P    +P +PLP+   +   P
Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%)

Query: 28  RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87
           RP +P+     +  + P  PP      PP  PS   ++S   +     P  VP PPP P 
Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 88  SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146
           +A Q P  P P  P      + HP P     PP+ PP+  P +PPV  A P   T P   
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414

Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202
            P      +P PPPPP +P       PPG    +  P +  +  + PS   P+ + +  P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465

Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232
           H   +PP P   +  A   +R P  L    D R
Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%)

Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133
           V P  PP PPPM                                       P P  PP+P
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183
            A         M   PPP +P PPPPP        V P     Q  PG  H   PP +  
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392

Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
             Q +P    P A   ++P    +P +PLP+   +   P
Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%)

Query: 28  RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87
           RP +P+     +  + P  PP      PP  PS   ++S   +     P  VP PPP P 
Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 88  SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146
           +A Q P  P P  P      + HP P     PP+ PP+  P +PPV  A P   T P   
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414

Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202
            P      +P PPPPP +P       PPG    +  P +  +  + PS   P+ + +  P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465

Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232
           H   +PP P   +  A   +R P  L    D R
Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%)

Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133
           V P  PP PPPM                                       P P  PP+P
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183
            A         M   PPP +P PPPPP        V P     Q  PG  H   PP +  
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392

Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222
             Q +P    P A   ++P    +P +PLP+   +   P
Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 69/246 (28%), Positives = 88/246 (35%), Gaps = 63/246 (25%)

Query: 19  PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPP-------------SAP--STTF 63
           P   GGHG  P   +        + P  PP+     PP             S P  S  +
Sbjct: 402 PSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461

Query: 64  SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFP-PMPP 122
                   +PP P  +  PPP PPS Q P PP    PP+   Q + P P PP        
Sbjct: 462 RLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521

Query: 123 PMPCPNN-------------PP----------VPGAPPGQGTFPFMMP---------PPS 150
           P+P   N             PP           PGAP  QG  P M+P         PP 
Sbjct: 522 PLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN-PTMVPLPPGVQPPLPPG 580

Query: 151 MPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPY 210
            P PPPPP          PPG +   + PP       +PS+F+       +     +PP+
Sbjct: 581 APPPPPPP----------PPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVA----GMPPF 626

Query: 211 PLPKAP 216
            +P AP
Sbjct: 627 GMPPAP 632



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 56/182 (30%), Positives = 65/182 (35%), Gaps = 46/182 (25%)

Query: 13  HPGRGC--PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAP----------- 59
           H G+G   P   G     P  PS +P       P  P  Q Q +PP  P           
Sbjct: 464 HQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-GPLPPWQQQQQQPPPPPPPSSSMASSTP 522

Query: 60  ------STTFSNSPAPNFLPP--RPDFVPFPPPMPPSAQG-----PLPPCPIRPPFPNHQ 106
                 +TT + S     +PP  +        P  P  QG     PLPP  ++PP P   
Sbjct: 523 LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLP--- 578

Query: 107 MRHPFPVPPCFPPMPPP-----MPCPNNPPVPGAPPG-----QGTFPFMMPPPSMPHPPP 156
              P   PP  PP PPP     M  P  PP P   P       G     MPP  MP  PP
Sbjct: 579 ---PGAPPP--PPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633

Query: 157 PP 158
           PP
Sbjct: 634 PP 635



 Score = 38.5 bits (88), Expect = 0.044
 Identities = 45/139 (32%), Positives = 52/139 (37%), Gaps = 19/139 (13%)

Query: 46  QPPVQYQYEPPSAPSTT-FSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF-- 102
           + PV       S P+TT  +++P P      P     PPP   S     PP     P   
Sbjct: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNP-----PPPSLMSTTQSRPPWMNSGPSES 376

Query: 103 -PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSM-PHPPPPPVM 160
            P H M    P  P   P   P P P+     G  P Q   P   PPP M P PPP    
Sbjct: 377 RPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN-PNGPPPPWMQPPPPPMNQG 435

Query: 161 PQQVNYQYPPGYSHHNFPP 179
           P      +PPG  HH  PP
Sbjct: 436 P------HPPG--HHGPPP 446



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 8/69 (11%)

Query: 69  PNFLPPRPDFVPFPPPMPPS-------AQGPLPPCPIRPP-FPNHQMRHPFPVPPCFPPM 120
           P   PP P   P PPP PP        A  P PP P+ P  F          +PP   P 
Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPP 630

Query: 121 PPPMPCPNN 129
            PP P P N
Sbjct: 631 APPPPPPQN 639


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 66/211 (31%), Positives = 77/211 (36%), Gaps = 49/211 (23%)

Query: 55  PPSAP----STTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGP------LPPCPIRP---- 100
           PPSAP    S+  S  P P   PP      FPPP+PP    P      +PP P+ P    
Sbjct: 217 PPSAPNPVVSSLGSGLPPPGMPPPGS----FPPPVPPPGALPPGIPPAMPPPPMPPGAAG 272

Query: 101 -----------PFPNHQMRHPFPVPPCFPPMP--PPMPCPNNPP-----VPGAPPGQGTF 142
                        P H   HP P PP   P P    M   ++ P         PPG G  
Sbjct: 273 HGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQ 332

Query: 143 PFMMPPPSMPHPPPPPV-MPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201
           P   PPP MPHP PPP+ MP     + PP  S    P P        P   +P    +  
Sbjct: 333 PPPRPPPGMPHPGPPPMGMPP----RGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGP 388

Query: 202 PHFRHL--------PPYPLPKAPSERRSPER 224
           P             PP P P+ P   R P R
Sbjct: 389 PRPPPYGYQRGPLPPPRPTPRPPVPPRGPLR 419



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 50/150 (33%), Positives = 59/150 (39%), Gaps = 15/150 (10%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73
           PG G P G G     P  P   P      HP    +Q  +  P       +  P     P
Sbjct: 281 PGAGHP-GHGHSHPHPFPPGGMP------HPGMSQMQLAHHGPHGLGHPHAGPPGSGGQP 333

Query: 74  PRPDFVPFPPP-MPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132
           P     P PPP MP     P+   P  PPF +  M HP P+PP     PPP+  P+    
Sbjct: 334 P-----PRPPPGMPHPGPPPMGMPPRGPPFGS-PMGHPGPMPPHGMRGPPPLMPPHGYTG 387

Query: 133 PGAPPGQGTFPFMMPPP-SMPHPPPPPVMP 161
           P  PP  G     +PPP   P PP PP  P
Sbjct: 388 PPRPPPYGYQRGPLPPPRPTPRPPVPPRGP 417



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 49/153 (32%), Positives = 53/153 (34%), Gaps = 28/153 (18%)

Query: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQ------------- 90
           P  PP    + PPSA  T  +  P      P P F P   P P  +Q             
Sbjct: 264 PPMPPGAAGHGPPSA-GTPGAGHPGHGHSHPHP-FPPGGMPHPGMSQMQLAHHGPHGLGH 321

Query: 91  ---GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP 147
              GP       PP P   M HP P P   PP  PP   P   P P  P G    P +MP
Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMP 381

Query: 148 PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180
           P     PP PP          P GY     PPP
Sbjct: 382 PHGYTGPPRPP----------PYGYQRGPLPPP 404



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 24/145 (16%)

Query: 88  SAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP 147
           +AQ PL     RP    HQ+    P PP   P P      +  P PG PP  G+FP  +P
Sbjct: 196 AAQNPLSQAD-RP----HQLFADAPPPPS-APNPVVSSLGSGLPPPGMPP-PGSFPPPVP 248

Query: 148 PP-SMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRH 206
           PP ++P P  PP MP       PPG + H             PS+  P A +    H  H
Sbjct: 249 PPGALP-PGIPPAMPPP---PMPPGAAGH-----------GPPSAGTPGAGHPGHGH-SH 292

Query: 207 LPPYPLPKAPSERRSPERLKHYDDH 231
             P+P    P    S  +L H+  H
Sbjct: 293 PHPFPPGGMPHPGMSQMQLAHHGPH 317


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 50/183 (27%), Positives = 82/183 (44%), Gaps = 32/183 (17%)

Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDR-------RERGRSPDRRRQDSR-------- 264
           R  +R +  ++   R++ H + +RHR  DR       RER +  DR+RQ  R        
Sbjct: 19  RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETER 78

Query: 265 ---YRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSR 321
               +   +R R   R R  +R RER+RE  R+R+  R    ER  + E +R   R   R
Sbjct: 79  QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138

Query: 322 EKKRAR---------WEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLK 372
           +++R R          + E+ RW++ +   K++     K++  +E    K EE+  E  K
Sbjct: 139 QRERERQRQRERKRETDRERQRWAEREERKKER-----KKERKKERKEKKKEEKRREDKK 193

Query: 373 PVW 375
             W
Sbjct: 194 RKW 196



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 52/156 (33%), Positives = 72/156 (46%), Gaps = 15/156 (9%)

Query: 223 ERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYRS---DYDRGRTPSR 277
           ER K  D  R R+    R  ER R   R RER R  DR R   R R    + DR R  +R
Sbjct: 57  ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116

Query: 278 HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSD 337
               ER ++ ERER R R+ +R    ER  ++E KR   R      +R RW E ++R  +
Sbjct: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDR------ERQRWAEREERKKE 170

Query: 338 NQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKP 373
            +   K +     KEK+ EE   +  + +  E + P
Sbjct: 171 RKKERKKER----KEKKKEEKRREDKKRKWGEGISP 202



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 6/150 (4%)

Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRGRTPSRH 278
           R  E  +  D  R R++   R  RHR  DR RER R  DR ++  R + + DR R   R 
Sbjct: 13  RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK-ERDRQRQRERE 71

Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDN 338
              E  R+RER+R R R  +     ++   +E KR   R+  R +K  R   E+D+ ++ 
Sbjct: 72  TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR---ERDKQTER 128

Query: 339 QSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368
           +   +++     +E+E +     K E + E
Sbjct: 129 ERD-RERERQRQRERERQRQRERKRETDRE 157



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 41/123 (33%), Positives = 58/123 (47%), Gaps = 5/123 (4%)

Query: 219 RRSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRGRTPSR 277
           +R  ER +  D  R +D      ER R  DR RER R   R R D +   + DR R   R
Sbjct: 83  QRQRERKRQTDRERDKDRDR---ERKRETDRNRERNRKGGRER-DKQTERERDRERERQR 138

Query: 278 HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSD 337
            R  ER R+RER+R   R+ +R    E   K+  K        ++K+  R E++K +W +
Sbjct: 139 QRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198

Query: 338 NQS 340
             S
Sbjct: 199 GIS 201



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 8/142 (5%)

Query: 232 RHRDHSHGRG---ERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERE 288
           R R+   G+    ER R  +R  +    +R RQ  R+R   +R R   R +  ER +ER+
Sbjct: 7   RKRETDRGKETERERDRQRERENQTERENRHRQRDRHR---ERDRQTDREKERERQKERD 63

Query: 289 RERHRHRDNRRSP--SLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKN 346
           R+R R R+  R      ER  ++E KR   R   +++ R R  E       N+  G++++
Sbjct: 64  RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123

Query: 347 YTSIKEKEPEETMPDKNEEEEE 368
             + +E++ E     + E E +
Sbjct: 124 KQTERERDRERERQRQRERERQ 145



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 5/126 (3%)

Query: 249 RRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRH--RDNRRSPSLERS 306
           +RER R  DR ++  R R         +   +  R R+R RER R   R+  R    ER 
Sbjct: 4   QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63

Query: 307 YKKEYKRSGSRSPSREKKRARWEEEK---DRWSDNQSSGKDKNYTSIKEKEPEETMPDKN 363
            +++ +R   R   R+++R R  E K   DR  D     + K  T    +   +   +++
Sbjct: 64  RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123

Query: 364 EEEEEE 369
           ++ E E
Sbjct: 124 KQTERE 129



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 14/114 (12%)

Query: 260 RQDSRYRSDYDRGRTPSRHRSYERSRE-------RERERHRHRDNRRSPSLERSYKKEYK 312
           RQ  R R + DRG+   R R  +R RE       R R+R RHR+  R    E+  +++ +
Sbjct: 3   RQRERKR-ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61

Query: 313 RSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEE 366
           R   R   RE +R     E +R  + Q   + K  T  +E++ +     K E +
Sbjct: 62  RDRQRQRERETER-----ETERQRERQRQRERKRQTD-RERDKDRDRERKRETD 109



 Score = 39.7 bits (91), Expect = 0.020
 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 6/105 (5%)

Query: 270 DRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWE 329
           +R R   R     +  ERER+R R R+N+      R  +++  R   R   REK+R R +
Sbjct: 2   ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQK 60

Query: 330 E-----EKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369
           E     +++R ++ ++  + +     + K   +   DK+ + E +
Sbjct: 61  ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK 105


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 72/248 (29%), Positives = 89/248 (35%), Gaps = 50/248 (20%)

Query: 35  RPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQG--P 92
           RP   R   P  PP   +   PS P  + S+   P   PP P   P PPP+PPS+ G   
Sbjct: 274 RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP---PPPPPSRPGPPPLPPSSSGNDE 330

Query: 93  LPPCPIR--------PPFPNHQMRHPFPVPPC-------------FPPMPPPMPCPNNPP 131
            P  P R        PP P+     P P PP                P+PPP P   N  
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390

Query: 132 VPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSF---NSFQNN 188
              A P     P      S    P PP+ P + +   PP       PPPS    N FQ++
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP------PPPSTSIRNGFQDS 444

Query: 189 PSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLD 248
           P      +     P    LPP P P   + +  P +L              R E     +
Sbjct: 445 PCEDEWESRFYFHP-ISDLPP-PEPYVQTTKSYPSKL-------------ARNESRSGSN 489

Query: 249 RRERGRSP 256
           RRERG  P
Sbjct: 490 RRERGAPP 497



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/246 (30%), Positives = 92/246 (37%), Gaps = 62/246 (25%)

Query: 14  PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYE--PPSAPSTT--FSNSPAP 69
           PGR  P    GH + P      PQ  R+  P +P V  + +  PP  PST     +SP  
Sbjct: 147 PGR-FPVPSPGHRSGPP----EPQRNRM-PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200

Query: 70  NFLPP------RPDFVPFPPPMPPSA----------QGPLP---PCPIRPPFPNHQMRHP 110
              PP      +P   P PPP P +           Q PL    P   RPP P    R  
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL 260

Query: 111 FPVPPCFPP------------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPP 158
              PP  PP            +PPP P  N PPVP  P    +     PPP    P PPP
Sbjct: 261 DDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320

Query: 159 VMPQQVNYQYPPGYSHHNFPP--PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216
           +         PP  S ++  P  P  N   ++ +  LPS   S           PLP  P
Sbjct: 321 L---------PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG----------PLPPPP 361

Query: 217 SERRSP 222
           SER  P
Sbjct: 362 SERPPP 367



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 48/160 (30%), Positives = 55/160 (34%), Gaps = 29/160 (18%)

Query: 64  SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPP 123
           S    P  LPP        P  PPS  G  P      P P H+           PP P  
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-----PSPGHRSG---------PPEPQR 166

Query: 124 MPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183
              P  PP P      G+ P  +PPP    P P    P        PG      P P+  
Sbjct: 167 NRMP--PPRPDV----GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220

Query: 184 SFQNNPSSFL------PSANNSSSPHFRHLPPYPLPKAPS 217
            F  N  + L       S  +SSSP F + P  PLP  PS
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSP-FSNRP--PLPPTPS 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,182,757
Number of Sequences: 37866
Number of extensions: 4152092
Number of successful extensions: 66044
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 708
Number of HSP's successfully gapped in prelim test: 1548
Number of HSP's that attempted gapping in prelim test: 23923
Number of HSP's gapped (non-prelim): 17626
length of query: 1337
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1223
effective length of database: 13,930,794
effective search space: 17037361062
effective search space used: 17037361062
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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