BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] (1337 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 2812 0.0 gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 2791 0.0 gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 93 2e-18 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 89 2e-17 gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 87 1e-16 gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 87 1e-16 gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 86 2e-16 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 84 9e-16 gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 79 2e-14 gi|52426743 cisplatin resistance-associated overexpressed protei... 79 3e-14 gi|19923485 cisplatin resistance-associated overexpressed protei... 79 3e-14 gi|160707881 formin 2 [Homo sapiens] 79 4e-14 gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 78 6e-14 gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 78 6e-14 gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 78 6e-14 gi|11386183 WAS protein family, member 2 [Homo sapiens] 77 8e-14 gi|47132519 Ras association and pleckstrin homology domains 1 is... 77 1e-13 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 75 3e-13 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 4e-13 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 75 5e-13 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 74 9e-13 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 74 9e-13 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 1e-12 gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 1e-12 gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 1e-12 gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 74 1e-12 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 74 1e-12 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 73 2e-12 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 72 3e-12 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 72 3e-12 >gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] Length = 1337 Score = 2812 bits (7289), Expect = 0.0 Identities = 1337/1337 (100%), Positives = 1337/1337 (100%) Query: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS Sbjct: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 Query: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM Sbjct: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 Query: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP Sbjct: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 Query: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR Sbjct: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 Query: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS Sbjct: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 Query: 301 PSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMP 360 PSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMP Sbjct: 301 PSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMP 360 Query: 361 DKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQE 420 DKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQE Sbjct: 361 DKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQE 420 Query: 421 KAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDR 480 KAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDR Sbjct: 421 KAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDR 480 Query: 481 LHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRIT 540 LHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRIT Sbjct: 481 LHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRIT 540 Query: 541 VSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMP 600 VSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMP Sbjct: 541 VSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMP 600 Query: 601 ENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVL 660 ENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVL Sbjct: 601 ENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVL 660 Query: 661 SMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQL 720 SMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQL Sbjct: 661 SMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQL 720 Query: 721 DREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQK 780 DREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQK Sbjct: 721 DREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQK 780 Query: 781 LAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLM 840 LAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLM Sbjct: 781 LAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLM 840 Query: 841 HLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHM 900 HLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHM Sbjct: 841 HLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHM 900 Query: 901 RKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLA 960 RKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLA Sbjct: 901 RKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLA 960 Query: 961 TYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSL 1020 TYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSL Sbjct: 961 TYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSL 1020 Query: 1021 EEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVI 1080 EEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVI Sbjct: 1021 EEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVI 1080 Query: 1081 FTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLL 1140 FTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLL Sbjct: 1081 FTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLL 1140 Query: 1141 RSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYV 1200 RSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYV Sbjct: 1141 RSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYV 1200 Query: 1201 HTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHART 1260 HTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHART Sbjct: 1201 HTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHART 1260 Query: 1261 YTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRW 1320 YTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRW Sbjct: 1261 YTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRW 1320 Query: 1321 EREHQEREPDETEDIKK 1337 EREHQEREPDETEDIKK Sbjct: 1321 EREHQEREPDETEDIKK 1337 >gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] Length = 1374 Score = 2791 bits (7236), Expect = 0.0 Identities = 1336/1374 (97%), Positives = 1336/1374 (97%), Gaps = 37/1374 (2%) Query: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS Sbjct: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 Query: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM Sbjct: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 Query: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP Sbjct: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 Query: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR Sbjct: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 Query: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS Sbjct: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 Query: 301 PSLERSYKKEYKRSGS-------------------------------------RSPSREK 323 PSLERSYKKEYKRSG RSPSREK Sbjct: 301 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK 360 Query: 324 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 383 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN Sbjct: 361 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 420 Query: 384 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 443 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS Sbjct: 421 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 480 Query: 444 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 503 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA Sbjct: 481 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 540 Query: 504 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 563 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI Sbjct: 541 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 600 Query: 564 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 623 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY Sbjct: 601 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 660 Query: 624 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 683 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA Sbjct: 661 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 720 Query: 684 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 743 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA Sbjct: 721 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 780 Query: 744 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 803 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV Sbjct: 781 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 840 Query: 804 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 863 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP Sbjct: 841 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 900 Query: 864 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 923 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS Sbjct: 901 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 960 Query: 924 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 983 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR Sbjct: 961 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 1020 Query: 984 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1043 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN Sbjct: 1021 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1080 Query: 1044 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1103 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL Sbjct: 1081 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1140 Query: 1104 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1163 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA Sbjct: 1141 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1200 Query: 1164 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1223 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND Sbjct: 1201 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1260 Query: 1224 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1283 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA Sbjct: 1261 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1320 Query: 1284 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1337 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK Sbjct: 1321 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1374 >gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] Length = 588 Score = 92.8 bits (229), Expect = 2e-18 Identities = 85/264 (32%), Positives = 106/264 (40%), Gaps = 36/264 (13%) Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173 PP FPP PP P P +P PP T P ++PPP +P PPP P PPG Sbjct: 342 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGIPITVPPPGFPP------PPG-- 392 Query: 174 HHNFPPPS-FNSFQNNPSSFLPSANNSSSPH----FRHLPPYPLPKAPS----------- 217 PPPS + ++ SS S + + P+ F HLP P PS Sbjct: 393 ---APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG-SAPSWPSLVDTSKQWDYY 448 Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPS 276 RR +R + D R RD R ER R+ RER R D S + SD +R R Sbjct: 449 ARREKDRDRERDRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREY 504 Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWS 336 R YER R + RHR+ R E +K S R S E R K + S Sbjct: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKS 562 Query: 337 DNQSSGKDKNYTSIKEKEPEETMP 360 GK+ E+E E P Sbjct: 563 KRSKEGKEAGSEPAPEQESTEATP 586 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 89.4 bits (220), Expect = 2e-17 Identities = 104/369 (28%), Positives = 128/369 (34%), Gaps = 92/369 (24%) Query: 19 PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDF 78 P+G G G P A P R P P P P P P PP P Sbjct: 198 PQGGRGRGRFPGAV---PGGDRFPGPAGPG------GPPPPFPAGQTPPRPPLGPPGPPG 248 Query: 79 VPFPPP----MPPSAQGP-----LPPCPI--------RPPFPNHQMRHPFPVPPCFPPMP 121 P PPP +PP GP PP P+ +PP P PVP PP Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308 Query: 122 PPMPCPNNPP----VPGAPPGQGTFPF-MMPPPSMPHPPP----------PPVMPQQVN- 165 PP P PP P PPG P + PPP +P PPP P P N Sbjct: 309 PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 Query: 166 ---------------YQYPPGYSHHNFPPP--------------SFNSFQNNPSSFLPSA 196 Y PP Y ++ PP F N + SA Sbjct: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSA 428 Query: 197 -----NNSSSPHF--------RHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 +++S+ + + K ++ R + D H S G Sbjct: 429 ISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYG-- 486 Query: 244 HRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSL 303 S RRER R D R SR +S + R+ RH Y R R RERERHR RD R Sbjct: 487 --SGSRRERSRERDHSR--SREKSRRHKSRSRDRHDDYYRERSRERERHRDRD--RDRDR 540 Query: 304 ERSYKKEYK 312 ER ++EY+ Sbjct: 541 ERDREREYR 549 Score = 88.2 bits (217), Expect = 5e-17 Identities = 94/339 (27%), Positives = 122/339 (35%), Gaps = 66/339 (19%) Query: 19 PRGRGGH------GARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFL 72 P G GG G P P P PP Q P + P P P Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIR--PPFPNHQMRHPFPVPPCFPPMPP-----PMP 125 P +P P P+PP GP PP P PP P + P P P FPP PP P+ Sbjct: 280 PGQPFGQPPLGPLPP---GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336 Query: 126 CPNNPPVPGAPPGQG-----TFPFMMPPPSMPHPP------PPPVMPQQVNYQYPPGYSH 174 P +PG PPG P PPP+ P PPP P Y PP Y Sbjct: 337 LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDP----YGRPPPYDR 392 Query: 175 HNFPPPS--------------FNSFQNNPSSFLPSA-----NNSSSPHFRH--------L 207 ++ PP F N + SA +++S+ + + Sbjct: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAI 452 Query: 208 PPYPLPKAPSERRSPERLKHYDDHRH--RDHSHGRGERHRSLDRRERGRSPDR-RRQDSR 264 K ++ R + D H S+G G R R+ RS ++ RR SR Sbjct: 453 SLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSR 512 Query: 265 YRSDYD-----RGRTPSRHRSYERSRERERERHRHRDNR 298 R +D R R RHR +R R+RER+R R +R Sbjct: 513 SRDRHDDYYRERSRERERHRDRDRDRDRERDREREYRHR 551 >gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] Length = 520 Score = 86.7 bits (213), Expect = 1e-16 Identities = 79/253 (31%), Positives = 99/253 (39%), Gaps = 23/253 (9%) Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171 PP FPP PP P P +P PP T P ++PPP P PP PPP + + + G Sbjct: 283 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 341 Query: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228 Y S FP + N LP S+P + L RR +R + Sbjct: 342 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 391 Query: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287 D R RD R ER R+ RER R D S + SD +R R R YER R Sbjct: 392 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 447 Query: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNY 347 + RHR+ R E +K S R S E R K + S GK+ Sbjct: 448 REKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKSKRSKEGKEAGS 505 Query: 348 TSIKEKEPEETMP 360 E+E E P Sbjct: 506 EPAPEQESTEATP 518 >gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] Length = 594 Score = 86.7 bits (213), Expect = 1e-16 Identities = 79/253 (31%), Positives = 99/253 (39%), Gaps = 23/253 (9%) Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171 PP FPP PP P P +P PP T P ++PPP P PP PPP + + + G Sbjct: 357 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 415 Query: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228 Y S FP + N LP S+P + L RR +R + Sbjct: 416 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 465 Query: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287 D R RD R ER R+ RER R D S + SD +R R R YER R Sbjct: 466 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 521 Query: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNY 347 + RHR+ R E +K S R S E R K + S GK+ Sbjct: 522 REKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKSKRSKEGKEAGS 579 Query: 348 TSIKEKEPEETMP 360 E+E E P Sbjct: 580 EPAPEQESTEATP 592 >gi|119226260 calcium homeostasis endoplasmic reticulum protein [Homo sapiens] Length = 916 Score = 85.9 bits (211), Expect = 2e-16 Identities = 88/314 (28%), Positives = 114/314 (36%), Gaps = 41/314 (13%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP-VPPCF--PPMPPPMPCPNNPPVPGAP 136 PF PP +GP PP P F H F PP F PP P P Sbjct: 513 PFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFD 572 Query: 137 PGQGTFPFMMPPPS------MPHPP----PPPVMPQQVNYQYPP-------------GYS 173 QG FP M PP MPHP PP PQ ++ PP G Sbjct: 573 YPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPP 632 Query: 174 HHNFPPPSFNS---FQNNPSSFLPSANNSSSPHFRHLPP----YPLPKAPSERRSPERLK 226 H N PS + + P+ + ++ L P P P PSER Sbjct: 633 HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEA 692 Query: 227 HYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRE 286 Y H + G L R + RRR+ R+ PSR RS +SR Sbjct: 693 FYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNS-----GPSRSRSRSKSRG 747 Query: 287 RERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKN 346 R R R ++ S S RS + RS SRS SR + R+R + R +QS + K+ Sbjct: 748 RSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSR---SQSRSRSKS 804 Query: 347 YTSIKEKEPEETMP 360 Y+ + + P Sbjct: 805 YSPGRRRRSRSRSP 818 Score = 44.3 bits (103), Expect = 8e-04 Identities = 71/292 (24%), Positives = 91/292 (31%), Gaps = 63/292 (21%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR--PP 101 P PP P P+T +S P +P ++ P+A GP P P PP Sbjct: 357 PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPP 416 Query: 102 FPNHQMRHPFPVPPC---FPPMPPPMPCPNNPPVPGAPP-------------------GQ 139 P PV P PP PP P P P PP GQ Sbjct: 417 NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGP-PHCPPWNNSHEGMWGEQRGDPGWNGQ 475 Query: 140 GTFP------------FMMPPPSMPHPPP-------PPV---MPQQVNYQYPPGYSHHNF 177 P F P S PP PP P +PP H F Sbjct: 476 RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQF 535 Query: 178 -PPPSFNSFQNNPSSFL----PSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHR 232 PP ++F P F+ P + P + H YP P+E P H+ HR Sbjct: 536 NQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPH---HHPGHR 592 Query: 233 H-----RDHSHGRGERHRSL---DRRERGRSPDRRRQDSRYRSDYDRGRTPS 276 +H G +H G+ P RRQ + + D P+ Sbjct: 593 MPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPN 644 Score = 42.0 bits (97), Expect = 0.004 Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 12/111 (10%) Query: 82 PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT 141 PPP PP A P P P P Q PP P P P A +G Sbjct: 356 PPPAPPPAPAPAPAIP-----PTTQPDD--SKPPIQMPGSSEYEAPGGVQDPAAAGPRGP 408 Query: 142 FPFMMPPPSMP--HPPPPPVMP--QQVNYQYPPGYSHHNFPPPSFNSFQNN 188 P PP+ P P PV P QQ + PP Y HH PP + N+ Sbjct: 409 GPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPP-YPHHQGGPPHCPPWNNS 458 Score = 33.5 bits (75), Expect = 1.4 Identities = 25/94 (26%), Positives = 33/94 (35%), Gaps = 17/94 (18%) Query: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPV-MPQQVNYQYPPGYSH-----------HNF 177 PP P PP P +PP + P PP+ MP Y+ P G H+ Sbjct: 355 PPPPAPPPAPAPAP-AIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQ 413 Query: 178 PPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYP 211 PP+ + + P P PPYP Sbjct: 414 IPPNKPPWFDQPHPVAPWGQQQPPEQ----PPYP 443 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 84.0 bits (206), Expect = 9e-16 Identities = 74/231 (32%), Positives = 97/231 (41%), Gaps = 38/231 (16%) Query: 21 GRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVP 80 G+ G G APS R N + P PP P +T+ ++ A PPRP+ Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPAS-----PRLGNTSEAHGAART-APPRPNVPA 173 Query: 81 FPPPMPPSAQGPLPP-----CPIR-----PPFPNHQMRHPFPVPP--CFPPMPPPMPCPN 128 PPP PP PLPP PI+ PP P + P PP C PP PPP P P Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233 Query: 129 NPPVPGAP--PGQGTFPFMMPPPSMPHPPPPPVMP-------------QQVNYQYPPGYS 173 PP+P A + P + P P PPP P++P + Q PP Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP 293 Query: 174 HHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPER 224 P S + + P+ LP N+SS PP P PK+PS + P++ Sbjct: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETP----PPLP-PKSPSFQAPPQK 339 Score = 55.1 bits (131), Expect = 5e-07 Identities = 58/199 (29%), Positives = 68/199 (34%), Gaps = 70/199 (35%) Query: 25 HGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPA------------PNFL 72 HGA +AP RP N+ P PP PP PS++ +P P Sbjct: 159 HGAARTAPP-RP-NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVA 216 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPC------------------PIRPPFP----------- 103 PP P P PPP PP PLPP PI PP P Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLK 276 Query: 104 ------NHQMRHPFPVPPCFPPMPPPMPCPNN-----PPVPGA-------PPGQGTFPFM 145 + P P PP PP+PP C PP+PG PP P Sbjct: 277 AEPASPAQDAQEP-PAPP--PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF 333 Query: 146 MPPP------SMPHPPPPP 158 PP ++P PP PP Sbjct: 334 QAPPQKAGAQALPAPPAPP 352 Score = 48.9 bits (115), Expect = 3e-05 Identities = 42/134 (31%), Positives = 49/134 (36%), Gaps = 35/134 (26%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSP-----APNFLPPRPDFVPFPPPM--------PPS-- 88 P PP PP P++ S+ AP LPP P +P PP P S Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283 Query: 89 --AQGPLPPCPIRPPFPNHQMRHPFPVPPCF---------PPMPPPMPCPNNPP------ 131 AQ P P P PP+ + R P PP PP+PP P PP Sbjct: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343 Query: 132 ---VPGAPPGQGTF 142 P APPG F Sbjct: 344 ALPAPPAPPGSQPF 357 Score = 36.2 bits (82), Expect = 0.22 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Query: 110 PFPVPPCFPPMPPPMPCPNNPPVPGAPP 137 P P PP PP PPP+ P PP P APP Sbjct: 4 PPPPPPPLPPPPPPLGAP-PPPPPSAPP 30 Score = 35.4 bits (80), Expect = 0.37 Identities = 21/41 (51%), Positives = 22/41 (53%), Gaps = 13/41 (31%) Query: 112 PVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMP 152 PVPP P PPP+P P PP GAPP PPPS P Sbjct: 2 PVPP---PPPPPLPPP--PPPLGAPP--------PPPPSAP 29 Score = 32.7 bits (73), Expect = 2.4 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 23/54 (42%) Query: 79 VPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132 +P PPP PP PLPP P PP P PPP P+ PPV Sbjct: 1 MPVPPPPPP----PLPP----------------PPPPLGAPPPPP---PSAPPV 31 Score = 32.3 bits (72), Expect = 3.1 Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 7/54 (12%) Query: 120 MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173 MP P P P PP+P PP P PPP P PP + P G S Sbjct: 1 MPVPPPPP--PPLPPPPP-----PLGAPPPPPPSAPPVSTDTSSLRRADPKGRS 47 Score = 32.0 bits (71), Expect = 4.1 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 14/43 (32%) Query: 119 PMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMP 161 P+PPP P PP+P PP P P PPPP P Sbjct: 2 PVPPPPP----PPLPPPPP----------PLGAPPPPPPSAPP 30 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 79.3 bits (194), Expect = 2e-14 Identities = 58/160 (36%), Positives = 66/160 (41%), Gaps = 18/160 (11%) Query: 26 GARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPP-- 83 GA +AP+ P L PQ P PP P P +PPRP P PP Sbjct: 221 GAYYAAPALDPALCVHLVPQLP------RPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMA 274 Query: 84 PMPP-SAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMP--PPM-PCPNNPPVPGAPPGQ 139 P+PP S P+PP P P P P P P P+P PPM P P PP+ PPG Sbjct: 275 PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGP 334 Query: 140 GTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPP 179 PP P PP PP+ P PPG PP Sbjct: 335 PMARVPPGPPMAPLPPGPPMAP------LPPGPPMAPLPP 368 Score = 66.2 bits (160), Expect = 2e-10 Identities = 49/138 (35%), Positives = 57/138 (41%), Gaps = 21/138 (15%) Query: 32 PSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNS----PAPNF--LPPRPDFVPFP--P 83 P P+ + P +PP+ PP AP S P P +PP P P P P Sbjct: 250 PPMPPRPPMVPMPPRPPIAPM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP 307 Query: 84 PMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFP 143 PM P GP P P+ PP P P P PP PP P P PP+ PPG Sbjct: 308 PMAPVPTGP-PMAPV-PPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG----- 360 Query: 144 FMMPPPSMPHPPPPPVMP 161 PP P PP PP+ P Sbjct: 361 ----PPMAPLPPGPPMAP 374 Score = 42.7 bits (99), Expect = 0.002 Identities = 26/79 (32%), Positives = 28/79 (35%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114 PP P P +PP P PP P + P PP PP P P P Sbjct: 304 PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPM 363 Query: 115 PCFPPMPPPMPCPNNPPVP 133 PP PP P P VP Sbjct: 364 APLPPGPPMAPLPPRSHVP 382 Score = 32.3 bits (72), Expect = 3.1 Identities = 21/52 (40%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPP 95 P PP+ PP P P LPP P P PP PP A PLPP Sbjct: 331 PPGPPMARV--PPGPPMAPLPPGPPMAPLPPGPPMAPLPPG-PPMA--PLPP 377 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 79.0 bits (193), Expect = 3e-14 Identities = 59/164 (35%), Positives = 79/164 (48%), Gaps = 14/164 (8%) Query: 214 KAPSERRSPERLKHYDDH-RHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRG 272 K E R ER + ++ R R E+ R+ DR R RS R R SR SD Sbjct: 251 KQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR-TSD---- 305 Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARW---- 328 R SR R ++RSR RER R R RD RRS S +RS +K RS R S+ + R + Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365 Query: 329 ---EEEKDRWS-DNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368 + E+DR S + + G D +S+K E+ D N E +E Sbjct: 366 KSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKE 409 Score = 54.7 bits (130), Expect = 6e-07 Identities = 44/138 (31%), Positives = 61/138 (44%), Gaps = 6/138 (4%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYRSDYDR 271 ++ S R R R RDH R ER RS R R R RS DR + R RS DR Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR-DR 350 Query: 272 GRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEE 331 R+ SR R + R + R+R + R ++ KK +SGSR E E Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT---ES 407 Query: 332 KDRWSDNQSSGKDKNYTS 349 K+ + N+ +G ++ S Sbjct: 408 KESDTKNEVNGTSEDIKS 425 Score = 53.1 bits (126), Expect = 2e-06 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%) Query: 219 RRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRH 278 +RS R +H R S R + R R RS DRRR S RS+ + R+ SR Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER-KHRSRSRD 349 Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDN 338 R +SR+R+ ++HR R +R K++ KR S K +R ++ +D +++ Sbjct: 350 RRRSKSRDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407 Query: 339 QSS 341 + S Sbjct: 408 KES 410 Score = 30.8 bits (68), Expect = 9.1 Identities = 40/197 (20%), Positives = 73/197 (37%), Gaps = 28/197 (14%) Query: 277 RHRSYERSRERERE-RHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRW 335 +H Y + + E + + R P + KKE + REK+R R EE++R Sbjct: 216 QHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQER----EEREKEREREREERERK 271 Query: 336 SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGD 395 + ++K +E+ ++ + RC+ S ++ S ++ Sbjct: 272 RRREEEEREKERARDRERRKRSRSRSRHSSRTSDR------RCSRSRDHKRSRSRER--- 322 Query: 396 STVVGTSRLRD-----LYDKFEEELGS-----RQEKAKAARPPWEPPKTKLDEDLESSSE 445 SR RD +D+ E + S R+ K++ + K++ E S E Sbjct: 323 ----RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378 Query: 446 SECESDEDSTCSSSSDS 462 E +D S S S Sbjct: 379 KEKRGSDDKKSSVKSGS 395 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 79.0 bits (193), Expect = 3e-14 Identities = 59/164 (35%), Positives = 79/164 (48%), Gaps = 14/164 (8%) Query: 214 KAPSERRSPERLKHYDDH-RHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRG 272 K E R ER + ++ R R E+ R+ DR R RS R R SR SD Sbjct: 251 KQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR-TSD---- 305 Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARW---- 328 R SR R ++RSR RER R R RD RRS S +RS +K RS R S+ + R + Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365 Query: 329 ---EEEKDRWS-DNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368 + E+DR S + + G D +S+K E+ D N E +E Sbjct: 366 KSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKE 409 Score = 54.7 bits (130), Expect = 6e-07 Identities = 44/138 (31%), Positives = 61/138 (44%), Gaps = 6/138 (4%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYRSDYDR 271 ++ S R R R RDH R ER RS R R R RS DR + R RS DR Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR-DR 350 Query: 272 GRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEE 331 R+ SR R + R + R+R + R ++ KK +SGSR E E Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT---ES 407 Query: 332 KDRWSDNQSSGKDKNYTS 349 K+ + N+ +G ++ S Sbjct: 408 KESDTKNEVNGTSEDIKS 425 Score = 53.1 bits (126), Expect = 2e-06 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%) Query: 219 RRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRH 278 +RS R +H R S R + R R RS DRRR S RS+ + R+ SR Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER-KHRSRSRD 349 Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDN 338 R +SR+R+ ++HR R +R K++ KR S K +R ++ +D +++ Sbjct: 350 RRRSKSRDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407 Query: 339 QSS 341 + S Sbjct: 408 KES 410 Score = 30.8 bits (68), Expect = 9.1 Identities = 40/197 (20%), Positives = 73/197 (37%), Gaps = 28/197 (14%) Query: 277 RHRSYERSRERERE-RHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRW 335 +H Y + + E + + R P + KKE + REK+R R EE++R Sbjct: 216 QHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQER----EEREKEREREREERERK 271 Query: 336 SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGD 395 + ++K +E+ ++ + RC+ S ++ S ++ Sbjct: 272 RRREEEEREKERARDRERRKRSRSRSRHSSRTSDR------RCSRSRDHKRSRSRER--- 322 Query: 396 STVVGTSRLRD-----LYDKFEEELGS-----RQEKAKAARPPWEPPKTKLDEDLESSSE 445 SR RD +D+ E + S R+ K++ + K++ E S E Sbjct: 323 ----RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378 Query: 446 SECESDEDSTCSSSSDS 462 E +D S S S Sbjct: 379 KEKRGSDDKKSSVKSGS 395 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 78.6 bits (192), Expect = 4e-14 Identities = 68/198 (34%), Positives = 82/198 (41%), Gaps = 26/198 (13%) Query: 44 PQQPPVQ-YQYEPPSAPSTTFSNSPAPNFLP-----PRPDF----VPFPPPMPPSAQGPL 93 PQ PP+Q + PP P + P P LP P P +P PPP+P +A P Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956 Query: 94 PPCP-----IRPPFPNHQMRHPFPVPPCFPPMPPPMPC---PNNPPVPGA---PPGQGTF 142 PP P + PP P + P P+P P PPP+P P PP+PGA PP Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016 Query: 143 PFMMPPPSMPHP--PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200 + PPP +P PPPP +P PP PPP P LP A Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076 Query: 201 SPHFRHL---PPYPLPKA 215 P PP PLP A Sbjct: 1077 PPPLPGAGIPPPPPLPGA 1094 Score = 72.4 bits (176), Expect = 3e-12 Identities = 62/190 (32%), Positives = 74/190 (38%), Gaps = 23/190 (12%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF----LPPRPDF----VPFPPPMPPSAQGPLPP 95 P PP+ PP P P P +PP P +P PPP+P + P PP Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035 Query: 96 CPIR-----PPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPS 150 P PP P + P P+P P PPP+P PP P PG G + PPP Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAG----IPPPPP 1090 Query: 151 MPHP--PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHL- 207 +P PPPP +P PP PPP P LP A P + Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150 Query: 208 --PPYPLPKA 215 PP PLP A Sbjct: 1151 IPPPPPLPGA 1160 Score = 66.6 bits (161), Expect = 1e-10 Identities = 55/170 (32%), Positives = 67/170 (39%), Gaps = 33/170 (19%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF----LPPRPDF----VPFPPPMPPSAQGPLPP 95 P PP+ PP P P P +PP P +P PPP+P P PP Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156 Query: 96 CPIR-----PPFPNHQMRHPFPVPPCFPPMPPPMPC---PNNPPVPGAP-------PGQG 140 P PP P + P P+P P PPP+P P PP+PGA PG G Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216 Query: 141 TFPF---MMPPPSMPHPPP-------PPVMPQQVNYQYPPGYSHHNFPPP 180 P +PPP PPP PP++PQ + P PPP Sbjct: 1217 IPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266 Score = 59.7 bits (143), Expect = 2e-08 Identities = 63/199 (31%), Positives = 73/199 (36%), Gaps = 38/199 (19%) Query: 46 QPP----VQYQYEPPSAPSTTFSNS---PAPNFLP--------PRPDFVPFPPPMPPSAQ 90 QPP ++Q + S+ F NS P+P LP P VP PPP P Sbjct: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT 887 Query: 91 GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPF------ 144 P P P P P PP PPP+P PP P P G G P Sbjct: 888 VPTLPSTAIPQPP------PLQGTEMLPPPPPPLPGAGIPPPPPLP-GAGILPLPPLPGA 940 Query: 145 -MMPPPSMPH---PPPPPVMPQQVNYQYP-PGYSHHNFPPPSFNSFQNNPSSFLPSANNS 199 + PPP +P PPPPP+ + P PG PPP P LP A Sbjct: 941 GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIP 998 Query: 200 SSPHFRHL---PPYPLPKA 215 P PP PLP A Sbjct: 999 PPPPLPGAGIPPPPPLPGA 1017 Score = 45.4 bits (106), Expect = 4e-04 Identities = 46/151 (30%), Positives = 56/151 (37%), Gaps = 24/151 (15%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNF-- 71 PG G P GA P P R+ P PP+ PP P P P Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLP---RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181 Query: 72 --LPPRPDF----VPFPPPMPPSAQGPLPPCPIR--PPFPNHQMRHPFPVPPCFPPMPPP 123 +PP P +P PPP+P + P PP P PP P P+PP +PPP Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP------PLPPPGTGIPPP 1235 Query: 124 MPCPNNPPVPGAPPGQGTFPF-----MMPPP 149 P + P G T P +PPP Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266 Score = 32.3 bits (72), Expect = 3.1 Identities = 29/117 (24%), Positives = 40/117 (34%), Gaps = 24/117 (20%) Query: 120 MPPPMPCPNNPPVP-GAPPGQGT------------------FPFMMPPPSMPHPPPPPVM 160 +PP P PP P GA G T P S+ PPPPP + Sbjct: 757 LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816 Query: 161 PQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPS 217 P H+ S +++ SS ++ N SP PP P ++ S Sbjct: 817 LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP-----PPLPCTESSS 868 >gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo sapiens] Length = 1125 Score = 77.8 bits (190), Expect = 6e-14 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%) Query: 24 GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81 G P+AP+ P P PV AP +P+ L RP +P Sbjct: 784 GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 838 Query: 82 -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134 PP MPP P P RP P+ R P P P F MPPP P P + P PG Sbjct: 839 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 897 Query: 135 APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 PG G P P PP P P P PQQ Q PPP+ Sbjct: 898 GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 954 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 Q P F N + F + RRS D R+ + + R Sbjct: 955 --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1004 Query: 244 HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299 +R DRRE G RSPDR R+R +R R S HR ER R+RE R ++ R Sbjct: 1005 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1054 Score = 74.7 bits (182), Expect = 5e-13 Identities = 96/390 (24%), Positives = 144/390 (36%), Gaps = 86/390 (22%) Query: 43 HPQQPPVQYQYEPPSAPSTTFSNSPAPNF---LPPRPDFVPF------PPPMPPSAQGPL 93 H PPV +PP+ T P P F +PP P PF P +PP P Sbjct: 685 HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 742 Query: 94 PPCPIRPPF---PNHQMRHPFP----------------------VPPCFP---PMPPPMP 125 PP PI PP P H P VPP P P PP Sbjct: 743 PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802 Query: 126 CPNNPPVPGAPPGQ------------GTFPFMMP---PPSMPHP--------PPPPVMPQ 162 + G PG G P ++P PP MP P PP P+ P Sbjct: 803 PVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPH 862 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 ++ PPG PPP P P P P P P P +R Sbjct: 863 MMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGGMPGLGG--PGPGPGGPEDRDGR 918 Query: 223 ERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSD----YDRGRTPSR- 277 ++ + + + + ++ + + P ++Q ++R+D ++ GR R Sbjct: 919 QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERF 978 Query: 278 -HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREK--------KRARW 328 RS+ E +RER+ +R++ R S ++ + G RSP R++ +R+ Sbjct: 979 GRRSFGNRVENDRERYGNRNDDRDNS-----NRDRREWGRRSPDRDRHRDLEERNRRSSG 1033 Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEET 358 +++R S ++ S ++K KEK PE T Sbjct: 1034 HRDRERDSRDRESRREKEEARGKEK-PEVT 1062 Score = 53.5 bits (127), Expect = 1e-06 Identities = 70/270 (25%), Positives = 87/270 (32%), Gaps = 29/270 (10%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102 P QP Q PP T F F P+ V +A P PP Sbjct: 238 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 297 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162 P + P P PPP P PG G M P H P+ Sbjct: 298 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 344 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 + Q P HH P P P + P PP P S + Sbjct: 345 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402 Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRS----PDRRRQDS-----RYRSDYD 270 E L H + +RH S +R+ R RS P RRR S R R Sbjct: 403 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS 462 Query: 271 RGRTPSRHRSYERSRERE-RERHRHRDNRR 299 R R+ R R RSR +E R+R + R+ R+ Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQ 492 Score = 52.4 bits (124), Expect = 3e-06 Identities = 48/150 (32%), Positives = 57/150 (38%), Gaps = 44/150 (29%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136 P P P+P P+PP P+ P P PP +PP P PPV GA Sbjct: 657 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 696 Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPPSFNSFQNNPS 190 P T P +PPP P PPPPP + N + PPG+ PPP P Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI-----TPPV 751 Query: 191 SFLPSANNSSSPHFRHLPPYPLPKAPSERR 220 S P H PP +P S R Sbjct: 752 SIPPP----------HTPPISIPNLVSGAR 771 Score = 52.0 bits (123), Expect = 4e-06 Identities = 46/127 (36%), Positives = 56/127 (44%), Gaps = 20/127 (15%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P++P + + S T SP P LP VP PP +P A +PP P P Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 683 Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHP- 154 HQ P PP F P +PPP P PP P PP G P +PP +P P Sbjct: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP-PG 742 Query: 155 PPPPVMP 161 PPPP+ P Sbjct: 743 PPPPITP 749 Score = 47.8 bits (112), Expect = 7e-05 Identities = 56/210 (26%), Positives = 73/210 (34%), Gaps = 22/210 (10%) Query: 56 PSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP 115 P AP+ T + AP P P PF P Q P + HQ F P Sbjct: 295 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ---------PAYTQHQNMDQFQ-PR 344 Query: 116 CFPPMPPPMPCPNNPPVPGAPPGQGTFPFM-MPPPSMPH-PPPPPVM-PQQVNYQ----- 167 PM P G PG G P PP + P PP PPV P Q ++Q Sbjct: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEP 404 Query: 168 --YPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS--PHFRHLPPYPLPKAPSERRSPE 223 P P + + S S + S+S P R + RRS Sbjct: 405 LTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRS 464 Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERG 253 R + H R S R +R + +RR++G Sbjct: 465 RSRDRRRHSPRSRSQERRDREKERERRQKG 494 Score = 33.5 bits (75), Expect = 1.4 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P R G P P +PQ PQQP Q Q +PP S P P Sbjct: 907 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 957 Query: 74 PR 75 P+ Sbjct: 958 PQ 959 >gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo sapiens] Length = 1132 Score = 77.8 bits (190), Expect = 6e-14 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%) Query: 24 GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81 G P+AP+ P P PV AP +P+ L RP +P Sbjct: 791 GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 845 Query: 82 -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134 PP MPP P P RP P+ R P P P F MPPP P P + P PG Sbjct: 846 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 904 Query: 135 APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 PG G P P PP P P P PQQ Q PPP+ Sbjct: 905 GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 961 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 Q P F N + F + RRS D R+ + + R Sbjct: 962 --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1011 Query: 244 HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299 +R DRRE G RSPDR R+R +R R S HR ER R+RE R ++ R Sbjct: 1012 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1061 Score = 68.2 bits (165), Expect = 5e-11 Identities = 97/412 (23%), Positives = 147/412 (35%), Gaps = 108/412 (26%) Query: 43 HPQQPPVQYQYEPPSAPSTTFSNSPAPNF---LPPRPDFVPF------PPPMPPSAQGPL 93 H PPV +PP+ T P P F +PP P PF P +PP P Sbjct: 670 HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 727 Query: 94 PPCPIRPPF---PNH----------------------QMRHPFP---------------- 112 PP PI PP P H + +P P Sbjct: 728 PPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSV 787 Query: 113 ------VPPCFP---PMPPPMPCPNNPPVPGAPPGQ------------GTFPFMMP---P 148 VPP P P PP + G PG G P ++P P Sbjct: 788 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 847 Query: 149 PSMPHP--------PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200 P MP P PP P+ P ++ PPG PPP P P Sbjct: 848 PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGG 905 Query: 201 SPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRR 260 P P P P P +R ++ + + + + ++ + + P ++ Sbjct: 906 MPGLGG--PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 963 Query: 261 QDSRYRSD----YDRGRTPSR--HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRS 314 Q ++R+D ++ GR R RS+ E +RER+ +R++ R S ++ + Sbjct: 964 QPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNS-----NRDRREW 1018 Query: 315 GSRSPSREK--------KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEET 358 G RSP R++ +R+ +++R S ++ S ++K KEK PE T Sbjct: 1019 GRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK-PEVT 1069 Score = 57.0 bits (136), Expect = 1e-07 Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P++P + + S T SP P LP VP PP +P A +PP P P Sbjct: 619 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 668 Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHPP 155 HQ P PP F P +PPP P PP P PP G P +PP +P P Sbjct: 669 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 728 Query: 156 PPPVMP 161 PPP+ P Sbjct: 729 PPPITP 734 Score = 53.5 bits (127), Expect = 1e-06 Identities = 70/270 (25%), Positives = 87/270 (32%), Gaps = 29/270 (10%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102 P QP Q PP T F F P+ V +A P PP Sbjct: 223 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 282 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162 P + P P PPP P PG G M P H P+ Sbjct: 283 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 329 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 + Q P HH P P P + P PP P S + Sbjct: 330 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 387 Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRS----PDRRRQDS-----RYRSDYD 270 E L H + +RH S +R+ R RS P RRR S R R Sbjct: 388 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS 447 Query: 271 RGRTPSRHRSYERSRERE-RERHRHRDNRR 299 R R+ R R RSR +E R+R + R+ R+ Sbjct: 448 RSRSRDRRRHSPRSRSQERRDREKERERRQ 477 Score = 51.6 bits (122), Expect = 5e-06 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 29/110 (26%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136 P P P+P P+PP P+ P P PP +PP P PPV GA Sbjct: 642 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 681 Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPP 180 P T P +PPP P PPPPP + N + PPG+ PPP Sbjct: 682 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPP 731 Score = 47.8 bits (112), Expect = 7e-05 Identities = 56/210 (26%), Positives = 73/210 (34%), Gaps = 22/210 (10%) Query: 56 PSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP 115 P AP+ T + AP P P PF P Q P + HQ F P Sbjct: 280 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ---------PAYTQHQNMDQFQ-PR 329 Query: 116 CFPPMPPPMPCPNNPPVPGAPPGQGTFPFM-MPPPSMPH-PPPPPVM-PQQVNYQ----- 167 PM P G PG G P PP + P PP PPV P Q ++Q Sbjct: 330 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEP 389 Query: 168 --YPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS--PHFRHLPPYPLPKAPSERRSPE 223 P P + + S S + S+S P R + RRS Sbjct: 390 LTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRS 449 Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERG 253 R + H R S R +R + +RR++G Sbjct: 450 RSRDRRRHSPRSRSQERRDREKERERRQKG 479 Score = 33.5 bits (75), Expect = 1.4 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P R G P P +PQ PQQP Q Q +PP S P P Sbjct: 914 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 964 Query: 74 PR 75 P+ Sbjct: 965 PQ 966 >gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo sapiens] Length = 1147 Score = 77.8 bits (190), Expect = 6e-14 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%) Query: 24 GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81 G P+AP+ P P PV AP +P+ L RP +P Sbjct: 806 GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 860 Query: 82 -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134 PP MPP P P RP P+ R P P P F MPPP P P + P PG Sbjct: 861 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 919 Query: 135 APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 PG G P P PP P P P PQQ Q PPP+ Sbjct: 920 GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 976 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 Q P F N + F + RRS D R+ + + R Sbjct: 977 --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1026 Query: 244 HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299 +R DRRE G RSPDR R+R +R R S HR ER R+RE R ++ R Sbjct: 1027 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1076 Score = 68.2 bits (165), Expect = 5e-11 Identities = 97/412 (23%), Positives = 147/412 (35%), Gaps = 108/412 (26%) Query: 43 HPQQPPVQYQYEPPSAPSTTFSNSPAPNF---LPPRPDFVPF------PPPMPPSAQGPL 93 H PPV +PP+ T P P F +PP P PF P +PP P Sbjct: 685 HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 742 Query: 94 PPCPIRPPF---PNH----------------------QMRHPFP---------------- 112 PP PI PP P H + +P P Sbjct: 743 PPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSV 802 Query: 113 ------VPPCFP---PMPPPMPCPNNPPVPGAPPGQ------------GTFPFMMP---P 148 VPP P P PP + G PG G P ++P P Sbjct: 803 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 862 Query: 149 PSMPHP--------PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200 P MP P PP P+ P ++ PPG PPP P P Sbjct: 863 PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGG 920 Query: 201 SPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRR 260 P P P P P +R ++ + + + + ++ + + P ++ Sbjct: 921 MPGLGG--PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 978 Query: 261 QDSRYRSD----YDRGRTPSR--HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRS 314 Q ++R+D ++ GR R RS+ E +RER+ +R++ R S ++ + Sbjct: 979 QPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNS-----NRDRREW 1033 Query: 315 GSRSPSREK--------KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEET 358 G RSP R++ +R+ +++R S ++ S ++K KEK PE T Sbjct: 1034 GRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK-PEVT 1084 Score = 57.0 bits (136), Expect = 1e-07 Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P++P + + S T SP P LP VP PP +P A +PP P P Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 683 Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHPP 155 HQ P PP F P +PPP P PP P PP G P +PP +P P Sbjct: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 743 Query: 156 PPPVMP 161 PPP+ P Sbjct: 744 PPPITP 749 Score = 53.5 bits (127), Expect = 1e-06 Identities = 70/270 (25%), Positives = 87/270 (32%), Gaps = 29/270 (10%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102 P QP Q PP T F F P+ V +A P PP Sbjct: 238 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 297 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162 P + P P PPP P PG G M P H P+ Sbjct: 298 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 344 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 + Q P HH P P P + P PP P S + Sbjct: 345 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402 Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRS----PDRRRQDS-----RYRSDYD 270 E L H + +RH S +R+ R RS P RRR S R R Sbjct: 403 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS 462 Query: 271 RGRTPSRHRSYERSRERE-RERHRHRDNRR 299 R R+ R R RSR +E R+R + R+ R+ Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQ 492 Score = 51.6 bits (122), Expect = 5e-06 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 29/110 (26%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136 P P P+P P+PP P+ P P PP +PP P PPV GA Sbjct: 657 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 696 Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPP 180 P T P +PPP P PPPPP + N + PPG+ PPP Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPP 746 Score = 47.8 bits (112), Expect = 7e-05 Identities = 56/210 (26%), Positives = 73/210 (34%), Gaps = 22/210 (10%) Query: 56 PSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP 115 P AP+ T + AP P P PF P Q P + HQ F P Sbjct: 295 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ---------PAYTQHQNMDQFQ-PR 344 Query: 116 CFPPMPPPMPCPNNPPVPGAPPGQGTFPFM-MPPPSMPH-PPPPPVM-PQQVNYQ----- 167 PM P G PG G P PP + P PP PPV P Q ++Q Sbjct: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEP 404 Query: 168 --YPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS--PHFRHLPPYPLPKAPSERRSPE 223 P P + + S S + S+S P R + RRS Sbjct: 405 LTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRS 464 Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERG 253 R + H R S R +R + +RR++G Sbjct: 465 RSRDRRRHSPRSRSQERRDREKERERRQKG 494 Score = 33.5 bits (75), Expect = 1.4 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P R G P P +PQ PQQP Q Q +PP S P P Sbjct: 929 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 979 Query: 74 PR 75 P+ Sbjct: 980 PQ 981 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 77.4 bits (189), Expect = 8e-14 Identities = 55/160 (34%), Positives = 63/160 (39%), Gaps = 9/160 (5%) Query: 36 PQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGP--L 93 P+ ++ P PP P P F+ PAP PP P + PPP PP G Sbjct: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPP--PPPPPMIGIPPPPPPVGFGSPGT 346 Query: 94 PPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPH 153 PP P P FP H F PP PP PP P PP P + P G P PPP Sbjct: 347 PPPPSPPSFPPHP---DFAAPPP-PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG- 401 Query: 154 PPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFL 193 PPPPP PP S P S + + S L Sbjct: 402 PPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLL 441 Score = 62.4 bits (150), Expect = 3e-09 Identities = 57/181 (31%), Positives = 70/181 (38%), Gaps = 32/181 (17%) Query: 29 PSAPSFRPQNLR---LLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM 85 P+ S+ N R L P++ V PP AP P P F PP P PPP Sbjct: 271 PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPP-----PAPPPP 325 Query: 86 PPSAQG-PLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPF 144 PP G P PP P+ P P P PP FPP P P PP Sbjct: 326 PPPMIGIPPPPPPVGFGSPGTP---PPPSPPSFPPHPD-FAAPPPPP------------- 368 Query: 145 MMPPPSMPHP--PPPPV-MPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201 PPP+ +P PPPP+ P PP PPP F P + P ++++ Sbjct: 369 --PPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQP-AIPPPLSDTTK 425 Query: 202 P 202 P Sbjct: 426 P 426 Score = 60.1 bits (144), Expect = 1e-08 Identities = 48/167 (28%), Positives = 56/167 (33%), Gaps = 34/167 (20%) Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMR----------------HPFPVPPC 116 PP P P P ++ LPP P +P R HP P PP Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306 Query: 117 FPP-------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYP 169 P PPP P P PP+ G PP P P P PP PP P ++ P Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP--PVGFGSPGTPPPPSPPSFPPHPDFAAP 364 Query: 170 PGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 P PPP + P L + P PP P P P Sbjct: 365 PPP-----PPPPAADYPTLPPPPLSQPTGGAPPP----PPPPPPPGP 402 Score = 60.1 bits (144), Expect = 1e-08 Identities = 50/147 (34%), Positives = 59/147 (40%), Gaps = 18/147 (12%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 P G P G A P AP P + + P PPV + P + S P P+F Sbjct: 304 PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA 363 Query: 74 PRPDFVPFPPPMPPSAQGP-LPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132 P PPP PP+A P LPP P+ P PP PP PPP P P PP Sbjct: 364 PP------PPPPPPAADYPTLPPPPLSQPTGG--------APP--PPPPPPPPGPPPPPF 407 Query: 133 PGAPPGQGTFPFMMPPPSMPHPPPPPV 159 GA GQ P + + P P V Sbjct: 408 TGA-DGQPAIPPPLSDTTKPKSSLPAV 433 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 76.6 bits (187), Expect = 1e-13 Identities = 67/213 (31%), Positives = 79/213 (37%), Gaps = 69/213 (32%) Query: 53 YEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP-----SAQGPLPPCPIRPPFPN--- 104 ++PP+ P S S P L P VP PPP PP SA L P P P P Sbjct: 684 FKPPTPPVMQ-SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA 742 Query: 105 -------HQMRHPFPVPPCFPPMPPPMPCPNNP--------------------------- 130 HQ++H V P PP PPP+P P P Sbjct: 743 PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA 802 Query: 131 ---PVPGAPPG--QGTFPFMMPPPSMPHPP---PPPVMPQQVNYQYPPGYSHHNFPPPSF 182 P P PP Q FP PPS P PP PPP +P+Q ++ PPPS Sbjct: 803 PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK--------PPPS- 853 Query: 183 NSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKA 215 P S +PS + F PP P P A Sbjct: 854 ------PLSPVPSVVKQIASQF---PPPPTPPA 877 Score = 63.2 bits (152), Expect = 2e-09 Identities = 67/210 (31%), Positives = 78/210 (37%), Gaps = 43/210 (20%) Query: 44 PQQPPVQYQYEPPSAPST-TFSNSPAPNFLPPRPDFVPF------PPPMPPSAQG-PLPP 95 P PPV PP+ P +F P P+ L P P V PPP PP+ + PL P Sbjct: 828 PPTPPVPVP--PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885 Query: 96 CP--IRPPFPNHQMRHP-------------FPVPP-----CFPPMPPPMPCPNNPPVPGA 135 P + P P P FP PP FPP PPP P P PP P Sbjct: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP-PPPSPVPAPPPPP-- 942 Query: 136 PPGQGTFPFMMPPP-------SMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNN 188 PP P P S P PP PQ+ + + H P P S + Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH--PEPKRPSVDSL 1000 Query: 189 PSSFLPSANNSSSPHFRHLPPYPLPKAPSE 218 S F P A S SP LPP P P + Sbjct: 1001 VSKFTPPA-ESGSPSKETLPPPAAPPKPGK 1029 Score = 60.1 bits (144), Expect = 1e-08 Identities = 67/217 (30%), Positives = 83/217 (38%), Gaps = 41/217 (18%) Query: 29 PSAPSFR--PQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM- 85 PS P F P L++ Q Q PP+ P +P P PP+P V P P Sbjct: 735 PSLPQFSAPPPPLKIHQVQHIT---QVAPPTPPPPPPIPAPLPPQAPPKP-LVTIPAPTS 790 Query: 86 ------------PPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFP-PMPPP-MP-----C 126 PP+ P+PP +P FP + P PP P P+PPP +P C Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP---PSPPTPPVPVPPPTLPKQQSFC 847 Query: 127 PNNPPVPGAPPGQ------GTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGY-SHHNFPP 179 PP P +P FP PP+M P PV P V Q PP + + P Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV-PANVAPQSPPAVKAKPKWQP 906 Query: 180 PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 S PS P SS F PP P+P P Sbjct: 907 SSIPV----PSPDFPPPPPESSLVFPPPPPSPVPAPP 939 Score = 60.1 bits (144), Expect = 1e-08 Identities = 58/189 (30%), Positives = 71/189 (37%), Gaps = 13/189 (6%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDF--VPFPPPMPPSAQG---PLPPCPIRP-PFPNHQMR 108 PP P+ PA +++PP P VP PPP P Q PP P+ P P Q+ Sbjct: 808 PPVPPAKKQPAFPA-SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866 Query: 109 HPFPVPPCFPPMP--PPMPCPNNPPVPGAPPGQGTFPFMMP---PPSMPHPPPPPVMPQQ 163 FP PP P M P P P N P +PP P P P P PPPP Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANV-APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSL 925 Query: 164 VNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPE 223 V PP PPP + S P S + P P P+ S +S Sbjct: 926 VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985 Query: 224 RLKHYDDHR 232 +H + R Sbjct: 986 GAEHPEPKR 994 Score = 55.8 bits (133), Expect = 3e-07 Identities = 54/200 (27%), Positives = 64/200 (32%), Gaps = 42/200 (21%) Query: 52 QYEPPSAPSTTFSNSPAPNFLPP---RPDFV----------PFPPPMPPSAQGPLPPCPI 98 Q E S N P + +PP +P V P PPP PP P PP P Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP 645 Query: 99 RPPFPNHQMRHPFPVPPCF---------------------PPMPPPMPCPNNPPVPGAPP 137 PP P+ P F PP PP M + P PP Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705 Query: 138 GQGTFPFMMPPPSMPHPPPPP--VMPQQVNYQYPPGYSHHNFPPPSFNSFQ-NNPSSFLP 194 ++PPP P PPP P M Q P + PPP Q + + P Sbjct: 706 NG-----VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760 Query: 195 SANNSSSPHFRHLPPYPLPK 214 P LPP PK Sbjct: 761 PTPPPPPPIPAPLPPQAPPK 780 Score = 50.1 bits (118), Expect = 1e-05 Identities = 48/161 (29%), Positives = 57/161 (35%), Gaps = 36/161 (22%) Query: 92 PLPPCP-IRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVP--GAPPGQGTFPFMMPP 148 PL P P I P+ Q P P PP PP PPP P P PP+P AP P + Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 Query: 149 PSMPH-------------PPPPPVMPQQ---------VNYQYPPGYSHHNFPPPSFNSFQ 186 ++ PP PPVM Q N PP P P Q Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727 Query: 187 NNPSSFLPSANNSSSP-------HFRHL----PPYPLPKAP 216 P+ PS S+P +H+ PP P P P Sbjct: 728 LKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768 Score = 44.3 bits (103), Expect = 8e-04 Identities = 52/207 (25%), Positives = 62/207 (29%), Gaps = 78/207 (37%) Query: 29 PSAPSFRPQNLRLLH----PQQPPV---QYQYEPPSAPSTTFSNSPAPN-----FLPPRP 76 P+ P+ Q L+ + PQ PP + +++P S P + P P F PP P Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932 Query: 77 DFVPFPPPMPPSAQGPLP---------------PCPIRPPFPNHQMR----------HPF 111 VP PPP PP P P P +PP P Q HP Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP-PTPQRNSSIKSSSGAEHPE 991 Query: 112 PVPPCF--------PPMPPPMPCPNNPPVPGAPPGQGTF--------------------- 142 P P PP P P P APP G Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051 Query: 143 -----------PFMMPPPSMPHPPPPP 158 F PP PPPPP Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPP 1078 Score = 41.2 bits (95), Expect = 0.007 Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 23/138 (16%) Query: 98 IRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPP 157 + P P ++ P+ PP+PPP P P PP P PP P PS P Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP-------PLPSQSAPSAG 658 Query: 158 PVMPQQVNY------QYPPGYSHHNFPPPS---FNSFQNNPSSFLPSANNSSSPHFRHLP 208 P V Y Q +S F PP+ S P +P N P P Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP--NGVVP-----P 711 Query: 209 PYPLPKAPSERRSPERLK 226 P P P P+ + +LK Sbjct: 712 PPPPPPPPTPGSAMAQLK 729 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 75.5 bits (184), Expect = 3e-13 Identities = 60/155 (38%), Positives = 77/155 (49%), Gaps = 20/155 (12%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR 273 ++PS++RS K DD R R R RRER RS D+RR SR DR R Sbjct: 25 RSPSDKRS----KRGDDRRSRSRDRDR--------RRERSRSRDKRRSRSR-----DRKR 67 Query: 274 TPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKD 333 R RS ER R RER R R RD RRS S R + G++S E R+R +E+ D Sbjct: 68 L-RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTE-NRSRSKEKTD 125 Query: 334 RWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368 ++ KDK+ EKE + D+N+ EEE Sbjct: 126 GGESSKEKKKDKD-DKEDEKEKDAGNFDQNKLEEE 159 Score = 71.2 bits (173), Expect = 6e-12 Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 15/146 (10%) Query: 239 GRGERHRSLDRRERGRSPDRRRQDS-----RYRSDYDRGRTPSRHRSYERSRERERERHR 293 GR RH RGRS R R S R D R R+ R R ERSR R++ R R Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61 Query: 294 HRDN---RRSPSLERSYKKEYKRSGSRSPSREKKRARWEE-------EKDRWSDNQSSGK 343 RD RRS S ER +E +RS SR R + R+R K + ++N+S K Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121 Query: 344 DKNYTSIKEKEPEETMPDKNEEEEEE 369 +K KE ++ DK +E+E++ Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEKEKD 147 Score = 43.1 bits (100), Expect = 0.002 Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 16/171 (9%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRE-RGRSPDRRRQDSRYRSDYDRG 272 K S R +RL+ R RD S R R RS DRR R RS RR + S + + Sbjct: 57 KRRSRSRDRKRLRR-SRSRERDRSRER-RRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKT 114 Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEK 332 SR + E +E+ + +D++ + + + + R+++ +W EE+ Sbjct: 115 ENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174 Query: 333 DRWSDNQSSGKDKNYTSIK-------------EKEPEETMPDKNEEEEEEL 370 + + K +K E +P E + NE E EEL Sbjct: 175 RKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEEL 225 Score = 37.7 bits (86), Expect = 0.074 Identities = 49/218 (22%), Positives = 83/218 (38%), Gaps = 24/218 (11%) Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGS--------RSPSREKKRARW 328 R + R R R R R RSPS +RS + + +RS S RS SR+K+R+R Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62 Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSD 388 + K R ++S +D++ + + + + +EN S Sbjct: 63 RDRK-RLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121 Query: 389 PMDQVGDSTVVGTSRLRDLYD------------KFEEELGSRQEKAKAARPPWEPPKTKL 436 G+S+ D D K EEE+ R+E+ + R E + K Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWR---EEQRKKA 178 Query: 437 DEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRK 474 E++ + E + S D + D AE +++ Sbjct: 179 MENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKE 216 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 75.1 bits (183), Expect = 4e-13 Identities = 62/187 (33%), Positives = 78/187 (41%), Gaps = 24/187 (12%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPA----PNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR 99 P PPVQ + PP++P + S +P P+ P P PP PP + PP Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727 Query: 100 PPFPNHQMRHPFPVPPCFPPMPPPM-PCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--- 155 PP ++ P P PP PPM P P P PP+ APP Q PP S+P P Sbjct: 728 PPLAAPPLQVP-PSPPASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMSPLAK 783 Query: 156 PPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKA 215 PPP P + P PP SF + F PSA+ SP P P+A Sbjct: 784 PPPQAPPAL---ATPPLQALPSPPASF----PGQAPFSPSASLPMSP-----LATPPPQA 831 Query: 216 PSERRSP 222 P +P Sbjct: 832 PPVLAAP 838 Score = 67.4 bits (163), Expect = 9e-11 Identities = 69/247 (27%), Positives = 86/247 (34%), Gaps = 32/247 (12%) Query: 29 PSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR-------PDFVPF 81 P +PS P + PP+Q PP++P + S +P P PP P P Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743 Query: 82 PPPMPPSAQGP--------LPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVP 133 PPM PSA P PP + P P P PP P PP + P +P Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP--PQAPPALATPPLQALP 801 Query: 134 GAP---PGQGTF----PFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQ 186 P PGQ F M P + P P PPV+ + Q PP PP+ + Q Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPS-------PPASPTLQ 853 Query: 187 NNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRS 246 P + S S L P P P R L D H + E R Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913 Query: 247 LDRRERG 253 D G Sbjct: 914 YDSGPEG 920 Score = 65.5 bits (158), Expect = 3e-10 Identities = 64/206 (31%), Positives = 76/206 (36%), Gaps = 32/206 (15%) Query: 47 PPVQYQYEPPSAPSTTFSNSP---APNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF- 102 PP+Q PP++P + +P APN L PF PP P Q P P P PP Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVS 686 Query: 103 ---------PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP------ 147 P P VPP PP PPM P+ P P APP P +P Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPS-PPASPPM-SPSATPPPQAPPPLAAPPLQVPPSPPAS 744 Query: 148 PPSMPHPPPPPVMPQQV---NYQYPPG------YSHHNFPPPSF-NSFQNNPSSFLPSAN 197 PP P PPP +P + Q PP S PPP + P LPS Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804 Query: 198 NSSSPHFRHLPPYPLPKAPSERRSPE 223 S P LP +P P+ Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQ 830 Score = 57.4 bits (137), Expect = 9e-08 Identities = 58/189 (30%), Positives = 65/189 (34%), Gaps = 56/189 (29%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQP-PVQYQYEPPSAPSTTFSNSPAPNFL 72 P R P RG P AP+ HP QP P Q P P Sbjct: 252 PARSGPSARG----TPRAPA---------HPSQPKPKGLQALRP------------PQVT 286 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP--------VPPCFPPMPP-P 123 PPR D P A GPL P+ P P+ P P +P PP PP Sbjct: 287 PPRKDAAP--------ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338 Query: 124 MPCPNNPPVPGAPPGQGTFPF------MMPPPSMPHPP--PPPVMPQQVNYQYPPGYSHH 175 P P PP P APP T P PPSM PP PP + PP H Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL-----QTIPPIQVPH 393 Query: 176 NFPPPSFNS 184 + PS + Sbjct: 394 SLTSPSLQA 402 Score = 52.0 bits (123), Expect = 4e-06 Identities = 62/217 (28%), Positives = 75/217 (34%), Gaps = 47/217 (21%) Query: 43 HPQQPPVQYQYEPP-----SAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPL---- 93 H Q P+ PP S + PA PP + PP +A PL Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557 Query: 94 ---PPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT-----FPFM 145 PPCP P P P PP P P P PP +PP QG P Sbjct: 558 LETPPCPA--PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615 Query: 146 MPPPSMPH----------PPP---PPVMPQQV-NYQYPPGYSHHNF-----PPPS----- 181 PPP P P P PP+ P + Q P + H PPPS Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675 Query: 182 -FNSFQNNPSSFLPSAN-NSSSPHFRHLPPYPLPKAP 216 F+ + P S PSA S +P PP +P +P Sbjct: 676 PFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSP 710 Score = 39.7 bits (91), Expect = 0.020 Identities = 62/253 (24%), Positives = 79/253 (31%), Gaps = 65/253 (25%) Query: 29 PSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR---PDFVPFPP-P 84 PS P P L P PP PS P+T S +P PP P PP Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTL--PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390 Query: 85 MPPSAQGP---LPPCPIRPPF---------PNHQMRHPF-------------------PV 113 +P S P PP P+ P Q H F Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450 Query: 114 PPCFPPMPPPMPCPNNPPV-----PGAPPGQGTF---PFMMPPPSMPHPPPPPVMPQQVN 165 PP PP+ P+ P +PP+ P P P H P P+ + Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS----S 506 Query: 166 YQYPPGYSHHNFPPPSFNS---------FQNNPSSFLPSANNSS----SPHFRHLP---P 209 PP + + PPS + +N PS P +S +PH P P Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566 Query: 210 YPLPKAPSERRSP 222 PL PS +P Sbjct: 567 CPLQAPPSPLTTP 579 Score = 32.0 bits (71), Expect = 4.1 Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 37/198 (18%) Query: 31 APSFRPQNLRLLHPQQPPVQYQYEPPSAPS--TTFSNSPAPNFLPPRPDFVPFPPPMPPS 88 APS RP+ PP + + S+ S +T SPA P + P S Sbjct: 193 APSARPR---------PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 89 AQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPP 148 + P+ P + P P P P P P PP + P + P Sbjct: 244 SSAT----PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299 Query: 149 PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLP 208 S P P P G PPP +N ++ LP+ S P Sbjct: 300 SSSPLATPS-----------PSGTKARPVPPP------DNAATPLPATLPPSPP-----L 337 Query: 209 PYPLPKAPSERRSPERLK 226 PLP AP +P L+ Sbjct: 338 ATPLPLAPPSPSAPPSLQ 355 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 74.7 bits (182), Expect = 5e-13 Identities = 53/161 (32%), Positives = 78/161 (48%), Gaps = 18/161 (11%) Query: 217 SERRSPERLKHYDDHRHRDHSHGRG--ERHRSLDRR-----ERGRSPDRRRQDSRYRSDY 269 + R ER K + R RD R ER R DR+ ER R +R+R+ R R + Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER-ER 309 Query: 270 DRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSRE-KKRARW 328 +R R R R ER RERER+R RD + +R + E R +R RE +++A Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369 Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 E E++R D QS+ +E+E E D++ ++E E Sbjct: 370 ERERERERDRQSA---------REREERERDRDRDRQKERE 401 Score = 68.9 bits (167), Expect = 3e-11 Identities = 61/250 (24%), Positives = 108/250 (43%), Gaps = 27/250 (10%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR 273 + P + SP R G G+ H+ D +R R+ + R+ R + +R Sbjct: 29 RRPGSQESPRR-------------RGLGQAHKDADGDDRERNRQKERERRREKRQTERET 75 Query: 274 TPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRAR-WEEEK 332 R R E+ R R+R+RHR R R ER +E R + +R+K+R R E E Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135 Query: 333 DRWSDNQSSG---KDKNYTSIKEKEPE-----ETMPDKNEEEEEELLKPVWIRCTHSENY 384 +R D Q+ G +++ + KE+E + + ++N ++E E K R E Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN---RQERRERE 192 Query: 385 YSSDPMDQVGD-STVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 443 + ++ D + G R R+ + E E + ++ + + E + K + E + Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK-QAERERA 251 Query: 444 SESECESDED 453 SE E E D++ Sbjct: 252 SERETERDKE 261 Score = 66.2 bits (160), Expect = 2e-10 Identities = 60/239 (25%), Positives = 97/239 (40%), Gaps = 35/239 (14%) Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDR---RERGRSPDRRRQDSRYRSDYDRGRT 274 ERR +R + R R+ + +RHR DR R+R R +R RQ R R Sbjct: 63 ERRREKRQTERETDRKRERRREK-DRHRKRDRHRERQRDREKERERQTDRERD------- 114 Query: 275 PSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDR 334 R R ER+R++ERER R+ R + ++E +R RE++ R + + Sbjct: 115 --RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172 Query: 335 WSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVG 394 + + ++KN +E+E + +K E+ E + R E ++ Q Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE---RERERETETETERKRQ-- 227 Query: 395 DSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDED 453 T R RD K E E + E+ +A+ + + E E E E D D Sbjct: 228 ------TDRERDRQRKTEREREKQAERERAS-----------ERETERDKERERERDRD 269 Score = 65.9 bits (159), Expect = 3e-10 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 1/153 (0%) Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRS-DYDRGRTPS 276 +RR ER + D R R R + +RER R +R R+ R R + +R R Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332 Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWS 336 R E+ RER+R+R D R+ R +++ +R R R+++ AR EE++R Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392 Query: 337 DNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 D + + T ET + E++ E Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRE 425 Score = 63.5 bits (153), Expect = 1e-09 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 15/159 (9%) Query: 223 ERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRGRTPSRHRSY 281 ER + D + R+ R ER R +R R++ R ++ RQ+ R R + R Sbjct: 148 ERERQRDAEKERERQTDR-ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206 Query: 282 ERSRERERERH------------RHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWE 329 ER RERERER R RD +R ER + E +R+ R R+K+R R E Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER-E 265 Query: 330 EEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368 ++DR D + +++ +++ E + + E + Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304 Score = 63.5 bits (153), Expect = 1e-09 Identities = 50/166 (30%), Positives = 73/166 (43%), Gaps = 20/166 (12%) Query: 223 ERLKHYDDHRHRDHSHGR-----GERHRSLDR-----RERGRSPDRRRQDSRYRSDYDRG 272 ER + D R R R ER R+ +R +ER R DR R R + + +R Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282 Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEE-- 330 R R ER RE ER+R R R+ R R ++E +R R RE +R R +E Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342 Query: 331 -------EKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 E DR N+ +G++ + +E+E E ++ E EE Sbjct: 343 RKRKRQTEMDR-ERNRQTGREGRRQAERERERERERDRQSAREREE 387 Score = 60.5 bits (145), Expect = 1e-08 Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 12/143 (8%) Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSR 277 + R +R + + R R+ GR R ++ RER R +R RQ +R R + +R R Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQA--ERERERERERDRQSAREREERERDR---- 392 Query: 278 HRSYERSRERERERHRHRDNRRSPSLERSYKK--EYKRSGSRSPSREKKRARWEEEKDRW 335 +R +ERER+ + RD +R +R +K E +R R REK++ R E +++R Sbjct: 393 --DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR-ERDRERQ 449 Query: 336 SDNQSSGKDKNYTSIKEKEPEET 358 +D Q +G+ + +++ P T Sbjct: 450 TDRQ-AGRQRKRSTLYVNPPPRT 471 Score = 60.1 bits (144), Expect = 1e-08 Identities = 66/255 (25%), Positives = 97/255 (38%), Gaps = 23/255 (9%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR 273 K ERR ER + ++ HS ER R RE +R+RQ R R DR R Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERE---RETETETERKRQTDRER---DRQR 236 Query: 274 TPSRHRSYERSRERERERHRHRDNRRSPSLERS-----YKKEYKRSGSRSPSREKKRARW 328 R R + RER ER RD R +R +KE +R R R +R R Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296 Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSD 388 E K + +++N +E+E E + E E + + R +E Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE------ 350 Query: 389 PMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESEC 448 MD+ + G R + E E R+ ++AR E + + D D + E + Sbjct: 351 -MDRERNRQ-TGREGRRQAERERERE---RERDRQSAREREERERDR-DRDRQKERERQT 404 Query: 449 ESDEDSTCSSSSDSE 463 E D D + E Sbjct: 405 EKDRDGQRETEKQRE 419 Score = 59.3 bits (142), Expect = 2e-08 Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 5/151 (3%) Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDRR-ERGRSPDRRRQDSRYRSDYDRGRTPSRH 278 R ER + + R+ R + +++ DR ERGR +R R+ ++ +R R R Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE---TETERKRQTDRE 231 Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRS-PSREKKRARWEEEKDRWSD 337 R +R ERERE+ R+ ER ++E +R R R+K+R R + K + Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291 Query: 338 NQSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368 + ++ +E+E E K E E E Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERE 322 Score = 57.8 bits (138), Expect = 7e-08 Identities = 48/154 (31%), Positives = 70/154 (45%), Gaps = 18/154 (11%) Query: 220 RSPERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYR-----SDYDRG 272 R ER + R R+ R ER R +R RER R +R R+ R R ++ DR Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354 Query: 273 RTPSRHRSYERSRERERERHRHRDNR---------RSPSLERSYKKEYKRSGSRSPSREK 323 R R R ERERER R RD + R +R ++E + R RE Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414 Query: 324 KRARWEEEKDRWSD-NQSSGKDKNYTSIKEKEPE 356 ++ R E EKDR S+ + G+++ +E++ E Sbjct: 415 EKQR-EREKDRESERGRERGREREKQKGRERDRE 447 Score = 37.7 bits (86), Expect = 0.074 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 259 RRQDSRYRSDYDRGRTPSRHRSYERSRERERERHR-HRDNRRSPSLERSYKKEYKRSGSR 317 RR+ S RG + + RER R++ R R +R E K+E +R R Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87 Query: 318 SPSREKKRARW---EEEKDRWSD---NQSSGKDKNYTSIKEKEPE 356 R++ R R E+E++R +D ++ K++N +E+E E Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE 132 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 73.9 bits (180), Expect = 9e-13 Identities = 76/282 (26%), Positives = 123/282 (43%), Gaps = 37/282 (13%) Query: 214 KAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRG 272 K ER+ E+ + + R R+ R ER R +R RER + +R R+ R R D DR Sbjct: 297 KKEKERQEIEKERR-ERERERERERERREREREREREREREKEKERERERERDR-DRDRT 354 Query: 273 RTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEK 332 + R R ER R+R+RER R+ RS S E+S +E +R R RE++R R E E+ Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER-ERER 413 Query: 333 DRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELL--KPVWIRCTHSENYYSSDPM 390 +R + + +E+E E+ EE+EE+ + + + E Y Sbjct: 414 ERERERE-----------REREREKDKKRDREEDEEDAYERRKLERKLREKEAAY----Q 458 Query: 391 DQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAAR----------PPWEPPKTKLDEDL 440 +++ + + + R+ + E E R+E AK A+ + PK L Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518 Query: 441 ES---SSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPD 479 + E E E+DE + E + I + + HPD Sbjct: 519 QKRLRDREKEMEADER---DRKREKEELEEIRQRLLAEGHPD 557 Score = 67.8 bits (164), Expect = 7e-11 Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 13/161 (8%) Query: 221 SPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRS 280 S E K D H+ + G+ E+ R +ER R +R R+ R R + +R R R R Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERERERERRERERERERERERE 336 Query: 281 YERSRERE----------RERHRHRDNR--RSPSLERSYKKEYKRSGSRSPSREKKRARW 328 E+ RERE +ER R RD R ERS + RS SR SR+++R R Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396 Query: 329 EEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 E + + +++ +E+E E K + EE+E Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDE 437 Score = 53.5 bits (127), Expect = 1e-06 Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 8/215 (3%) Query: 242 ERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERER-HRHRDNRRS 300 E R L RE + D ++ + ++ R ER RERERER R R+ R Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330 Query: 301 PSLERSYKKEYKRSGSRSPSREKKRAR---WEEEKDRWSDNQ-SSGKDKNYTSIKEKEPE 356 ER +KE +R R R++ + R + E+DR D + SS ++K+ + +EK + Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390 Query: 357 ETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYD--KFEEE 414 + E E E + R E + ++ D D Y+ K E + Sbjct: 391 RERERERERERERERERERERERERERERERE-REREKDKKRDREEDEEDAYERRKLERK 449 Query: 415 LGSRQEKAKAARPPWEPPKTKLDEDLESSSESECE 449 L ++ + WE + K + E +E E E Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484 Score = 48.1 bits (113), Expect = 6e-05 Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 10/159 (6%) Query: 223 ERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRT-PSRHRS- 280 ERLK+++ + E R +RR +R ++ + DYD R P +R Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE--FLEDYDDDRDDPKYYRGS 516 Query: 281 --YERSRERERERHR-HRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRW-- 335 +R R+RE+E RD +R ++ G P E +R E E+ R Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576 Query: 336 -SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKP 373 S +++ KE++ EE M ++ E E++ LKP Sbjct: 577 IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKP 615 Score = 37.4 bits (85), Expect = 0.097 Identities = 37/174 (21%), Positives = 66/174 (37%), Gaps = 27/174 (15%) Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHR 279 R ER + D R R+ R L+R+ R + R ++ R R +R Sbjct: 419 REREREREKDKKRDREEDEEDAYERRKLERKLREKEA---AYQERLKNWEIRERKKTREY 475 Query: 280 SYERSRERERERHRHRDNRRSPSL------ERSYKKEYKRSGSRSPSREKKRARWEEEKD 333 E RE ER R ++ +R +R K Y+ S + R++++ +E+D Sbjct: 476 EKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERD 535 Query: 334 R------------------WSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 R D + + + + ++P+ ++EEEEEE Sbjct: 536 RKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589 Score = 35.4 bits (80), Expect = 0.37 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 7/64 (10%) Query: 102 FPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMP 161 FP H R P +P P +PPP PPVP P M+P P P P V+ Sbjct: 3 FPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTP-------MIPVPMSIMAPAPTVLV 55 Query: 162 QQVN 165 V+ Sbjct: 56 PTVS 59 Score = 31.6 bits (70), Expect = 5.3 Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 6/46 (13%) Query: 81 FPPPM--PPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM 124 FPP + PP LPP P FP P PVPP P +P PM Sbjct: 3 FPPHLNRPPMGIPALPPGIPPPQFPG----FPPPVPPGTPMIPVPM 44 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 73.9 bits (180), Expect = 9e-13 Identities = 83/301 (27%), Positives = 111/301 (36%), Gaps = 52/301 (17%) Query: 56 PSAPST-TFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114 PS P+T F P P PP P +P PP +PP P P P +PP + + P Sbjct: 548 PSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFP-PGQPPPAGYSV-----PP 601 Query: 115 PCFPPMPPPMPCP-----------NNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQ 163 P FPP P + P N P APP F + P Sbjct: 602 PGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPP-LSREEFYREQRRLKEESKSPYSGS- 659 Query: 164 VNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPE 223 YS ++ S S+ S + S S + PPYP RR Sbjct: 660 -------SYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYP-------RRGRG 705 Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYD-RGRTPSRHRSYE 282 + ++Y R R SHG HRS R RSP RR SR RS RG++P++ + Sbjct: 706 KSRNY---RSRSRSHG---YHRS-----RSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQ 754 Query: 283 RSRERERERHRHRDNRRSPSLERSYKKEYKRS-GSRSPSREKKRARWEEEKDRWSDNQSS 341 ERE + + R K Y RS R P +++ WE + W + Sbjct: 755 GETERE-----YFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYK 809 Query: 342 G 342 G Sbjct: 810 G 810 Score = 50.1 bits (118), Expect = 1e-05 Identities = 78/355 (21%), Positives = 130/355 (36%), Gaps = 49/355 (13%) Query: 167 QYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFR-HLPPYPLPKAPSER----RS 221 +Y GY+ P PS N +P FLP N +SP R Y ++ R Sbjct: 806 KYYKGYAAGAQPRPSANRENFSPERFLP-LNIRNSPFTRGRREDYVGGQSHRSRNIGSNY 864 Query: 222 PERLKHYDDHRHRDHS------------HGRGERHRSLDRRERG---------------- 253 PE+L D H +D++ G+G +H+ +R +G Sbjct: 865 PEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 924 Query: 254 --RSP---DRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYK 308 R P + + DS + TP R + + R + K Sbjct: 925 KSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984 Query: 309 KEYKRSGSRSPSREK--KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEE 366 + K GS +E K A+ +EK D + ++ IK K EET N + Sbjct: 985 TKRKNDGSAVSKKENIVKPAKGPQEK---VDGERERSPRSEPPIK-KAKEETPKTDNTKS 1040 Query: 367 EEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDK--FEEELGSRQEKAKA 424 K I T + + S Q ++ V +++ Y K E+L +++EKAK Sbjct: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQ--ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKK 1098 Query: 425 ARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPD 479 +P K ++ + E + D +S+ S EV +++ ++K PD Sbjct: 1099 PNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD 1153 Score = 36.2 bits (82), Expect = 0.22 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 14/71 (19%) Query: 146 MPPPSMPHPPPPPVMPQQV---------NYQYP---PGYSHHNFPPPSFNSFQNNPSSFL 193 +PPP P PPP P++ + + Q P P S P PS +S +N SS Sbjct: 336 LPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLA 395 Query: 194 P--SANNSSSP 202 P S N SS+P Sbjct: 396 PPVSGNPSSAP 406 Score = 35.0 bits (79), Expect = 0.48 Identities = 43/216 (19%), Positives = 84/216 (38%), Gaps = 25/216 (11%) Query: 195 SANNSSSPHFRHLPPYPLPKAPSERRSPER--LKHYDDHRHRDHSHGRGERHRSLDRRER 252 S+N +P+ Y + S +R E+ L D R+ G++++ + R+ Sbjct: 1428 SSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDL 1487 Query: 253 GR-----------SPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERH--RHRDNRR 299 + SP R R+ +++ YD R +S +++ ++RE+H R+N+ Sbjct: 1488 PKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKE 1547 Query: 300 SPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETM 359 S + Y + EK++ + +K +S +E +E Sbjct: 1548 SSGNKLLYILNPPET-----QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAA 1602 Query: 360 --PDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQV 393 PD NE + E V ++ S S D D++ Sbjct: 1603 FEPDYNESDSE---SNVSVKEEESSGNISKDLKDKI 1635 Score = 33.5 bits (75), Expect = 1.4 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 29 PSAPSFRPQNLRLLHP-QQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM-- 85 P P RP R L P + P+ Q +P P T+ S PAP+ + PP+ Sbjct: 341 PPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSG 400 Query: 86 -PPSAQGPLP 94 P SA P+P Sbjct: 401 NPSSAPAPVP 410 Score = 32.3 bits (72), Expect = 3.1 Identities = 16/82 (19%), Positives = 36/82 (43%) Query: 252 RGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEY 311 R SP + S S S+ + ++ +++ ++ +H+ +++ E +K Sbjct: 1668 RSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQ 1727 Query: 312 KRSGSRSPSREKKRARWEEEKD 333 K + S++ K E+EKD Sbjct: 1728 KHKHKKKKSKKNKDKEKEKEKD 1749 Score = 31.6 bits (70), Expect = 5.3 Identities = 23/117 (19%), Positives = 46/117 (39%), Gaps = 2/117 (1%) Query: 255 SPDRRRQDSR--YRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYK 312 +P++R+ ++ S+ DR +S +S + R +H R S + + + ++ K Sbjct: 1381 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1440 Query: 313 RSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 KR + E R D+ S KD + E +P K + ++ Sbjct: 1441 TDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK 1497 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.074 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.074 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.074 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.074 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 73.6 bits (179), Expect = 1e-12 Identities = 69/246 (28%), Positives = 88/246 (35%), Gaps = 63/246 (25%) Query: 19 PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPP-------------SAP--STTF 63 P GGHG P + + P PP+ PP S P S + Sbjct: 402 PSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461 Query: 64 SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFP-PMPP 122 +PP P + PPP PPS Q P PP PP+ Q + P P PP Sbjct: 462 RLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521 Query: 123 PMPCPNN-------------PP----------VPGAPPGQGTFPFMMP---------PPS 150 P+P N PP PGAP QG P M+P PP Sbjct: 522 PLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN-PTMVPLPPGVQPPLPPG 580 Query: 151 MPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPY 210 P PPPPP PPG + + PP +PS+F+ + +PP+ Sbjct: 581 APPPPPPP----------PPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVA----GMPPF 626 Query: 211 PLPKAP 216 +P AP Sbjct: 627 GMPPAP 632 Score = 48.5 bits (114), Expect = 4e-05 Identities = 56/182 (30%), Positives = 65/182 (35%), Gaps = 46/182 (25%) Query: 13 HPGRGC--PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAP----------- 59 H G+G P G P PS +P P P Q Q +PP P Sbjct: 464 HQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-GPLPPWQQQQQQPPPPPPPSSSMASSTP 522 Query: 60 ------STTFSNSPAPNFLPP--RPDFVPFPPPMPPSAQG-----PLPPCPIRPPFPNHQ 106 +TT + S +PP + P P QG PLPP ++PP P Sbjct: 523 LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLP--- 578 Query: 107 MRHPFPVPPCFPPMPPP-----MPCPNNPPVPGAPPG-----QGTFPFMMPPPSMPHPPP 156 P PP PP PPP M P PP P P G MPP MP PP Sbjct: 579 ---PGAPPP--PPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633 Query: 157 PP 158 PP Sbjct: 634 PP 635 Score = 38.5 bits (88), Expect = 0.044 Identities = 45/139 (32%), Positives = 52/139 (37%), Gaps = 19/139 (13%) Query: 46 QPPVQYQYEPPSAPSTT-FSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF-- 102 + PV S P+TT +++P P P PPP S PP P Sbjct: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNP-----PPPSLMSTTQSRPPWMNSGPSES 376 Query: 103 -PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSM-PHPPPPPVM 160 P H M P P P P P P+ G P Q P PPP M P PPP Sbjct: 377 RPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN-PNGPPPPWMQPPPPPMNQG 435 Query: 161 PQQVNYQYPPGYSHHNFPP 179 P +PPG HH PP Sbjct: 436 P------HPPG--HHGPPP 446 Score = 36.6 bits (83), Expect = 0.17 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 8/69 (11%) Query: 69 PNFLPPRPDFVPFPPPMPPS-------AQGPLPPCPIRPP-FPNHQMRHPFPVPPCFPPM 120 P PP P P PPP PP A P PP P+ P F +PP P Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPP 630 Query: 121 PPPMPCPNN 129 PP P P N Sbjct: 631 APPPPPPQN 639 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 72.8 bits (177), Expect = 2e-12 Identities = 66/211 (31%), Positives = 77/211 (36%), Gaps = 49/211 (23%) Query: 55 PPSAP----STTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGP------LPPCPIRP---- 100 PPSAP S+ S P P PP FPPP+PP P +PP P+ P Sbjct: 217 PPSAPNPVVSSLGSGLPPPGMPPPGS----FPPPVPPPGALPPGIPPAMPPPPMPPGAAG 272 Query: 101 -----------PFPNHQMRHPFPVPPCFPPMP--PPMPCPNNPP-----VPGAPPGQGTF 142 P H HP P PP P P M ++ P PPG G Sbjct: 273 HGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQ 332 Query: 143 PFMMPPPSMPHPPPPPV-MPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201 P PPP MPHP PPP+ MP + PP S P P P +P + Sbjct: 333 PPPRPPPGMPHPGPPPMGMPP----RGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGP 388 Query: 202 PHFRHL--------PPYPLPKAPSERRSPER 224 P PP P P+ P R P R Sbjct: 389 PRPPPYGYQRGPLPPPRPTPRPPVPPRGPLR 419 Score = 62.4 bits (150), Expect = 3e-09 Identities = 50/150 (33%), Positives = 59/150 (39%), Gaps = 15/150 (10%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P G G P P P HP +Q + P + P P Sbjct: 281 PGAGHP-GHGHSHPHPFPPGGMP------HPGMSQMQLAHHGPHGLGHPHAGPPGSGGQP 333 Query: 74 PRPDFVPFPPP-MPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132 P P PPP MP P+ P PPF + M HP P+PP PPP+ P+ Sbjct: 334 P-----PRPPPGMPHPGPPPMGMPPRGPPFGS-PMGHPGPMPPHGMRGPPPLMPPHGYTG 387 Query: 133 PGAPPGQGTFPFMMPPP-SMPHPPPPPVMP 161 P PP G +PPP P PP PP P Sbjct: 388 PPRPPPYGYQRGPLPPPRPTPRPPVPPRGP 417 Score = 58.5 bits (140), Expect = 4e-08 Identities = 49/153 (32%), Positives = 53/153 (34%), Gaps = 28/153 (18%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQ------------- 90 P PP + PPSA T + P P P F P P P +Q Sbjct: 264 PPMPPGAAGHGPPSA-GTPGAGHPGHGHSHPHP-FPPGGMPHPGMSQMQLAHHGPHGLGH 321 Query: 91 ---GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP 147 GP PP P M HP P P PP PP P P P P G P +MP Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMP 381 Query: 148 PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 P PP PP P GY PPP Sbjct: 382 PHGYTGPPRPP----------PYGYQRGPLPPP 404 Score = 48.1 bits (113), Expect = 6e-05 Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 24/145 (16%) Query: 88 SAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP 147 +AQ PL RP HQ+ P PP P P + P PG PP G+FP +P Sbjct: 196 AAQNPLSQAD-RP----HQLFADAPPPPS-APNPVVSSLGSGLPPPGMPP-PGSFPPPVP 248 Query: 148 PP-SMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRH 206 PP ++P P PP MP PPG + H PS+ P A + H H Sbjct: 249 PPGALP-PGIPPAMPPP---PMPPGAAGH-----------GPPSAGTPGAGHPGHGH-SH 292 Query: 207 LPPYPLPKAPSERRSPERLKHYDDH 231 P+P P S +L H+ H Sbjct: 293 PHPFPPGGMPHPGMSQMQLAHHGPH 317 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 72.4 bits (176), Expect = 3e-12 Identities = 50/183 (27%), Positives = 82/183 (44%), Gaps = 32/183 (17%) Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDR-------RERGRSPDRRRQDSR-------- 264 R +R + ++ R++ H + +RHR DR RER + DR+RQ R Sbjct: 19 RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETER 78 Query: 265 ---YRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSR 321 + +R R R R +R RER+RE R+R+ R ER + E +R R R Sbjct: 79 QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138 Query: 322 EKKRAR---------WEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLK 372 +++R R + E+ RW++ + K++ K++ +E K EE+ E K Sbjct: 139 QRERERQRQRERKRETDRERQRWAEREERKKER-----KKERKKERKEKKKEEKRREDKK 193 Query: 373 PVW 375 W Sbjct: 194 RKW 196 Score = 68.2 bits (165), Expect = 5e-11 Identities = 52/156 (33%), Positives = 72/156 (46%), Gaps = 15/156 (9%) Query: 223 ERLKHYDDHRHRDHSHGRG-ERHRSLDR-RERGRSPDRRRQDSRYRS---DYDRGRTPSR 277 ER K D R R+ R ER R R RER R DR R R R + DR R +R Sbjct: 57 ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116 Query: 278 HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSD 337 ER ++ ERER R R+ +R ER ++E KR R +R RW E ++R + Sbjct: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDR------ERQRWAEREERKKE 170 Query: 338 NQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKP 373 + K + KEK+ EE + + + E + P Sbjct: 171 RKKERKKER----KEKKKEEKRREDKKRKWGEGISP 202 Score = 66.2 bits (160), Expect = 2e-10 Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 6/150 (4%) Query: 220 RSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRGRTPSRH 278 R E + D R R++ R RHR DR RER R DR ++ R + + DR R R Sbjct: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK-ERDRQRQRERE 71 Query: 279 RSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDN 338 E R+RER+R R R + ++ +E KR R+ R +K R E+D+ ++ Sbjct: 72 TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR---ERDKQTER 128 Query: 339 QSSGKDKNYTSIKEKEPEETMPDKNEEEEE 368 + +++ +E+E + K E + E Sbjct: 129 ERD-RERERQRQRERERQRQRERKRETDRE 157 Score = 62.4 bits (150), Expect = 3e-09 Identities = 41/123 (33%), Positives = 58/123 (47%), Gaps = 5/123 (4%) Query: 219 RRSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRYRSDYDRGRTPSR 277 +R ER + D R +D ER R DR RER R R R D + + DR R R Sbjct: 83 QRQRERKRQTDRERDKDRDR---ERKRETDRNRERNRKGGRER-DKQTERERDRERERQR 138 Query: 278 HRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSD 337 R ER R+RER+R R+ +R E K+ K ++K+ R E++K +W + Sbjct: 139 QRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198 Query: 338 NQS 340 S Sbjct: 199 GIS 201 Score = 62.0 bits (149), Expect = 4e-09 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 8/142 (5%) Query: 232 RHRDHSHGRG---ERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERE 288 R R+ G+ ER R +R + +R RQ R+R +R R R + ER +ER+ Sbjct: 7 RKRETDRGKETERERDRQRERENQTERENRHRQRDRHR---ERDRQTDREKERERQKERD 63 Query: 289 RERHRHRDNRRSP--SLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKN 346 R+R R R+ R ER ++E KR R +++ R R E N+ G++++ Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123 Query: 347 YTSIKEKEPEETMPDKNEEEEE 368 + +E++ E + E E + Sbjct: 124 KQTERERDRERERQRQRERERQ 145 Score = 49.7 bits (117), Expect = 2e-05 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 5/126 (3%) Query: 249 RRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRH--RDNRRSPSLERS 306 +RER R DR ++ R R + + R R+R RER R R+ R ER Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63 Query: 307 YKKEYKRSGSRSPSREKKRARWEEEK---DRWSDNQSSGKDKNYTSIKEKEPEETMPDKN 363 +++ +R R R+++R R E K DR D + K T + + +++ Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123 Query: 364 EEEEEE 369 ++ E E Sbjct: 124 KQTERE 129 Score = 44.7 bits (104), Expect = 6e-04 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Query: 260 RQDSRYRSDYDRGRTPSRHRSYERSRE-------RERERHRHRDNRRSPSLERSYKKEYK 312 RQ R R + DRG+ R R +R RE R R+R RHR+ R E+ +++ + Sbjct: 3 RQRERKR-ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61 Query: 313 RSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEE 366 R R RE +R E +R + Q + K T +E++ + K E + Sbjct: 62 RDRQRQRERETER-----ETERQRERQRQRERKRQTD-RERDKDRDRERKRETD 109 Score = 39.7 bits (91), Expect = 0.020 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 6/105 (5%) Query: 270 DRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWE 329 +R R R + ERER+R R R+N+ R +++ R R REK+R R + Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQK 60 Query: 330 E-----EKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 369 E +++R ++ ++ + + + K + DK+ + E + Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK 105 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 72.4 bits (176), Expect = 3e-12 Identities = 72/248 (29%), Positives = 89/248 (35%), Gaps = 50/248 (20%) Query: 35 RPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQG--P 92 RP R P PP + PS P + S+ P PP P P PPP+PPS+ G Sbjct: 274 RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP---PPPPPSRPGPPPLPPSSSGNDE 330 Query: 93 LPPCPIR--------PPFPNHQMRHPFPVPPC-------------FPPMPPPMPCPNNPP 131 P P R PP P+ P P PP P+PPP P N Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390 Query: 132 VPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSF---NSFQNN 188 A P P S P PP+ P + + PP PPPS N FQ++ Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP------PPPSTSIRNGFQDS 444 Query: 189 PSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLD 248 P + P LPP P P + + P +L R E + Sbjct: 445 PCEDEWESRFYFHP-ISDLPP-PEPYVQTTKSYPSKL-------------ARNESRSGSN 489 Query: 249 RRERGRSP 256 RRERG P Sbjct: 490 RRERGAPP 497 Score = 67.8 bits (164), Expect = 7e-11 Identities = 76/246 (30%), Positives = 92/246 (37%), Gaps = 62/246 (25%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYE--PPSAPSTT--FSNSPAP 69 PGR P GH + P PQ R+ P +P V + + PP PST +SP Sbjct: 147 PGR-FPVPSPGHRSGPP----EPQRNRM-PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200 Query: 70 NFLPP------RPDFVPFPPPMPPSA----------QGPLP---PCPIRPPFPNHQMRHP 110 PP +P P PPP P + Q PL P RPP P R Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL 260 Query: 111 FPVPPCFPP------------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPP 158 PP PP +PPP P N PPVP P + PPP P PPP Sbjct: 261 DDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320 Query: 159 VMPQQVNYQYPPGYSHHNFPP--PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 + PP S ++ P P N ++ + LPS S PLP P Sbjct: 321 L---------PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG----------PLPPPP 361 Query: 217 SERRSP 222 SER P Sbjct: 362 SERPPP 367 Score = 40.0 bits (92), Expect = 0.015 Identities = 48/160 (30%), Positives = 55/160 (34%), Gaps = 29/160 (18%) Query: 64 SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPP 123 S P LPP P PPS G P P P H+ PP P Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-----PSPGHRSG---------PPEPQR 166 Query: 124 MPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 P PP P G+ P +PPP P P P PG P P+ Sbjct: 167 NRMP--PPRPDV----GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220 Query: 184 SFQNNPSSFL------PSANNSSSPHFRHLPPYPLPKAPS 217 F N + L S +SSSP F + P PLP PS Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSP-FSNRP--PLPPTPS 257 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,182,757 Number of Sequences: 37866 Number of extensions: 4152092 Number of successful extensions: 66044 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 708 Number of HSP's successfully gapped in prelim test: 1548 Number of HSP's that attempted gapping in prelim test: 23923 Number of HSP's gapped (non-prelim): 17626 length of query: 1337 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1223 effective length of database: 13,930,794 effective search space: 17037361062 effective search space used: 17037361062 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.