Search of human proteins with 155030200

Search of human proteins with 155030200

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5
[Homo sapiens]
         (558 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5 [...  1064   0.0  
gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4 [...  1062   0.0  
gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3 [...  1041   0.0  
gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1 [...  1039   0.0  
gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2 [...  1033   0.0  
gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6 [...   923   0.0  
gi|39812229 karyopherin alpha 5 [Homo sapiens]                         59   1e-08
gi|222144293 karyopherin alpha 1 [Homo sapiens]                        57   4e-08
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              55   2e-07
gi|4504897 karyopherin alpha 2 [Homo sapiens]                          54   5e-07
gi|224589129 karyopherin 7 [Homo sapiens]                              52   1e-06
gi|6912478 karyopherin alpha 6 [Homo sapiens]                          49   2e-05
gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]     42   0.002
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]     41   0.003
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...    40   0.004
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                     40   0.007
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                     40   0.007
gi|31657114 armadillo repeat containing 4 [Homo sapiens]               38   0.021
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         37   0.048
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        37   0.048
gi|4504901 karyopherin alpha 4 [Homo sapiens]                          37   0.048
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]                37   0.062
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]                37   0.062
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]                37   0.062
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]               37   0.062
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]                37   0.062
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]               37   0.062
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]              37   0.062
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]                37   0.062
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]                37   0.062

>gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5
           [Homo sapiens]
          Length = 558

 Score = 1064 bits (2752), Expect = 0.0
 Identities = 558/558 (100%), Positives = 558/558 (100%)

Query: 1   MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP 60
           MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP
Sbjct: 1   MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP 60

Query: 61  QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS 120
           QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS
Sbjct: 61  QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS 120

Query: 121 HSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELV 180
           HSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELV
Sbjct: 121 HSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELV 180

Query: 181 KLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITEL 240
           KLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITEL
Sbjct: 181 KLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITEL 240

Query: 241 KTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDAN 300
           KTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDAN
Sbjct: 241 KTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDAN 300

Query: 301 CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLK 360
           CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLK
Sbjct: 301 CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLK 360

Query: 361 FLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL 420
           FLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL
Sbjct: 361 FLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL 420

Query: 421 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL 480
           LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL
Sbjct: 421 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL 480

Query: 481 ESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHEN 540
           ESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHEN
Sbjct: 481 ESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHEN 540

Query: 541 KSVAQQASLTEQRLTVES 558
           KSVAQQASLTEQRLTVES
Sbjct: 541 KSVAQQASLTEQRLTVES 558


>gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4
           [Homo sapiens]
          Length = 559

 Score = 1062 bits (2747), Expect = 0.0
 Identities = 557/557 (100%), Positives = 557/557 (100%)

Query: 2   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 61
           DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ
Sbjct: 3   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 62

Query: 62  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 121
           SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH
Sbjct: 63  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 122

Query: 122 SLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVK 181
           SLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVK
Sbjct: 123 SLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVK 182

Query: 182 LFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELK 241
           LFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELK
Sbjct: 183 LFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELK 242

Query: 242 TGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANC 301
           TGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANC
Sbjct: 243 TGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANC 302

Query: 302 IHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKF 361
           IHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKF
Sbjct: 303 IHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKF 362

Query: 362 LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL 421
           LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL
Sbjct: 363 LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL 422

Query: 422 SALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLE 481
           SALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLE
Sbjct: 423 SALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLE 482

Query: 482 SAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENK 541
           SAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENK
Sbjct: 483 SAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENK 542

Query: 542 SVAQQASLTEQRLTVES 558
           SVAQQASLTEQRLTVES
Sbjct: 543 SVAQQASLTEQRLTVES 559


>gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3
           [Homo sapiens]
          Length = 607

 Score = 1041 bits (2692), Expect = 0.0
 Identities = 558/607 (91%), Positives = 558/607 (91%), Gaps = 49/607 (8%)

Query: 1   MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP 60
           MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP
Sbjct: 1   MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP 60

Query: 61  QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS 120
           QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS
Sbjct: 61  QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS 120

Query: 121 H-------------------------------------------------SLQAQLINMG 131
           H                                                 SLQAQLINMG
Sbjct: 121 HEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMG 180

Query: 132 VIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDK 191
           VIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDK
Sbjct: 181 VIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDK 240

Query: 192 REMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLL 251
           REMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLL
Sbjct: 241 REMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLL 300

Query: 252 LGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVE 311
           LGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVE
Sbjct: 301 LGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVE 360

Query: 312 KLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF 371
           KLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF
Sbjct: 361 KLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF 420

Query: 372 KLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSK 431
           KLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSK
Sbjct: 421 KLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSK 480

Query: 432 DVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHR 491
           DVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHR
Sbjct: 481 DVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHR 540

Query: 492 LLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTE 551
           LLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTE
Sbjct: 541 LLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTE 600

Query: 552 QRLTVES 558
           QRLTVES
Sbjct: 601 QRLTVES 607


>gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1
           [Homo sapiens]
          Length = 608

 Score = 1039 bits (2687), Expect = 0.0
 Identities = 557/606 (91%), Positives = 557/606 (91%), Gaps = 49/606 (8%)

Query: 2   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 61
           DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ
Sbjct: 3   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 62

Query: 62  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 121
           SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH
Sbjct: 63  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 122

Query: 122 -------------------------------------------------SLQAQLINMGV 132
                                                            SLQAQLINMGV
Sbjct: 123 EGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGV 182

Query: 133 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 192
           IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR
Sbjct: 183 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 242

Query: 193 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 252
           EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL
Sbjct: 243 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 302

Query: 253 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 312
           GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK
Sbjct: 303 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 362

Query: 313 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 372
           LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK
Sbjct: 363 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 422

Query: 373 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 432
           LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD
Sbjct: 423 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 482

Query: 433 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 492
           VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL
Sbjct: 483 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 542

Query: 493 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 552
           LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ
Sbjct: 543 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 602

Query: 553 RLTVES 558
           RLTVES
Sbjct: 603 RLTVES 608


>gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2
           [Homo sapiens]
          Length = 607

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 556/606 (91%), Positives = 556/606 (91%), Gaps = 50/606 (8%)

Query: 2   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 61
           DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ
Sbjct: 3   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 62

Query: 62  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 121
           SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH
Sbjct: 63  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 122

Query: 122 -------------------------------------------------SLQAQLINMGV 132
                                                            SLQAQLINMGV
Sbjct: 123 EGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGV 182

Query: 133 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 192
           IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR
Sbjct: 183 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 242

Query: 193 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 252
           EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL
Sbjct: 243 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 302

Query: 253 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 312
           GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK
Sbjct: 303 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 362

Query: 313 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 372
           LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK
Sbjct: 363 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 422

Query: 373 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 432
           LLGTLRMLIDAQ EAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD
Sbjct: 423 LLGTLRMLIDAQ-EAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 481

Query: 433 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 492
           VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL
Sbjct: 482 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 541

Query: 493 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 552
           LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ
Sbjct: 542 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 601

Query: 553 RLTVES 558
           RLTVES
Sbjct: 602 RLTVES 607


>gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6
           [Homo sapiens]
          Length = 516

 Score =  923 bits (2386), Expect = 0.0
 Identities = 501/557 (89%), Positives = 506/557 (90%), Gaps = 43/557 (7%)

Query: 2   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 61
           DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ
Sbjct: 3   DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 62

Query: 62  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 121
           SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKD                   
Sbjct: 63  SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKD------------------- 103

Query: 122 SLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVK 181
             Q  L+  G      + LG  C ++                +SSKEQFASTNIAEELVK
Sbjct: 104 --QEVLLQTG------RALGNICYDS----------------QSSKEQFASTNIAEELVK 139

Query: 182 LFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELK 241
           LFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELK
Sbjct: 140 LFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELK 199

Query: 242 TGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANC 301
           TGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANC
Sbjct: 200 TGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANC 259

Query: 302 IHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKF 361
           IHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKF
Sbjct: 260 IHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKF 319

Query: 362 LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL 421
           LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL
Sbjct: 320 LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL 379

Query: 422 SALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLE 481
           SALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLE
Sbjct: 380 SALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLE 439

Query: 482 SAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENK 541
           SAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENK
Sbjct: 440 SAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENK 499

Query: 542 SVAQQASLTEQRLTVES 558
           SVAQQASLTEQRLTVES
Sbjct: 500 SVAQQASLTEQRLTVES 516


>gi|39812229 karyopherin alpha 5 [Homo sapiens]
          Length = 539

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 61/290 (21%), Positives = 125/290 (43%), Gaps = 21/290 (7%)

Query: 38  NTETSEKIQASGILQLFASLLTPQSSC--KAKVANIIAEVAKNEFMRIPCV-DAGLISPL 94
           N    + IQ  G++Q F   L    +C  + + A  +  +A   F+    V + G +   
Sbjct: 116 NPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIF 175

Query: 95  VQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCL 154
           ++LLNS+ ++V  Q   ALGNI  D+   +  ++N  ++P L++LL  +      T   +
Sbjct: 176 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELL-TNSNRLTTTRNAV 234

Query: 155 VAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQ-LV 213
            A  NL   ++    F+  +    ++       + D    +   L+ L++    K+Q ++
Sbjct: 235 WALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVI 294

Query: 214 EAGLVECLLEIVQQ---KVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQ 270
           ++G+   L+E++     KV S     +  + TG D+   ++L   ++  L          
Sbjct: 295 DSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCL---------- 344

Query: 271 RVLSWIPSNNHQLQLAGALAIANF-ARNDANCIHMVDNGIVEKLMDLLDR 319
             L  + S    ++      ++N  A N A    ++D  I   L+++L +
Sbjct: 345 --LHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQK 392


>gi|222144293 karyopherin alpha 1 [Homo sapiens]
          Length = 538

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 62/288 (21%), Positives = 122/288 (42%), Gaps = 21/288 (7%)

Query: 38  NTETSEKIQASGILQLFASLLTPQSSCKAKVAN--IIAEVAKNEFMRIPCV-DAGLISPL 94
           N    E I   G++  F   L  + +C  +  +  ++  +A    ++   V  AG +   
Sbjct: 115 NPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIF 174

Query: 95  VQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCL 154
           ++LL+S+ ++V  Q   ALGNI  DS   +  +++  ++P L++L         +T   +
Sbjct: 175 IELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ-NRLTMTRNAV 233

Query: 155 VAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQ-LV 213
            A  NL   +S   +FA  +    ++       + D        L+ L++    K+Q ++
Sbjct: 234 WALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVI 293

Query: 214 EAGLVECLLEIVQQ---KVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQ 270
           +AG+   L+E++     KV S     +  + TG D+   ++L   ++Q L          
Sbjct: 294 DAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSL---------- 343

Query: 271 RVLSWIPSNNHQLQLAGALAIANF-ARNDANCIHMVDNGIVEKLMDLL 317
             L  + S    ++      I+N  A N A    ++D  I   L+ +L
Sbjct: 344 --LHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISIL 389


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 99/477 (20%), Positives = 198/477 (41%), Gaps = 50/477 (10%)

Query: 86  VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQ 145
           +++   + +V +LNS ++E+L +   A+          +  L+ +G +  L KLL  H +
Sbjct: 22  IESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLL-TH-E 79

Query: 146 NAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAEN 205
           +  +     + FG LA     K+     ++   ++     + E    E     LA ++  
Sbjct: 80  DKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAE 139

Query: 206 DAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGK 265
              K+Q+ E G +E L+ ++     S  + D+   K   + +  L+   +   KL E   
Sbjct: 140 YTSKVQIFEHGGLEPLIRLL-----SSPDPDVK--KNSMECIYNLVQDFQCRAKLQE--- 189

Query: 266 GSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLD-RHVEDG 324
            +    +L  + S    +QL     +   A +  +   + DN  ++ L+ +L+ + + D 
Sbjct: 190 LNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDL 249

Query: 325 NVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRMLIDAQ 384
           ++     AL+ + N    +    ++   G  + +L F ++   P             D Q
Sbjct: 250 HI----EALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIP-------------DIQ 292

Query: 385 AEAAEQLGK------NVKLV-ERLVEWC----EAKDHAGVMGESNRLLSALIRHSKSKDV 433
             AA+ + K      N KL  E+ VE C       ++ G    +++ +SA+  +S SKD 
Sbjct: 293 KNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKD- 351

Query: 434 IKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLL 493
                 + GI  L+ +  S++  ++  A +ALA +       A    E A  +  L  LL
Sbjct: 352 ---FFNNQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAE-ADGIDPLINLL 407

Query: 494 ADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLD-VVSKLRSHENKSVAQQASL 549
           + +R       N+  ++  +   E L   +Q+   +  ++S LRS  N  V  +A+L
Sbjct: 408 SSKRDGAIA--NAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRS-ANTVVQSKAAL 461


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 81/389 (20%), Positives = 162/389 (41%), Gaps = 34/389 (8%)

Query: 34  LAQNNTETSEKIQASGILQLFASLL--TPQSSCKAKVANIIAEVAKNEFMRIPCV-DAGL 90
           L++      + I  +G++  F S L  T  S  + + A  +  +A     +   V D G 
Sbjct: 104 LSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGA 163

Query: 91  ISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALT 150
           I   + LL S    +  Q   ALGNI  D    +  +I  G +  L+ LL +   ++   
Sbjct: 164 IPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLAC 223

Query: 151 EMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLA-----EN 205
                    L+ L  +K      +  E+++    + + HD  E++ +    ++      N
Sbjct: 224 GYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPN 283

Query: 206 DAIKLQLVEAGLVECLLEIV---QQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFE 262
           + I + +V+ G+V  L++++   +  + +     I  + TG+         DE  Q + +
Sbjct: 284 ERIGM-VVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGT---------DEQTQVVID 333

Query: 263 GGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVE 322
            G  +VF  +L+  P  N Q +    ++     R D     +V++G+V  L+ +L +   
Sbjct: 334 AGALAVFPSLLT-NPKTNIQKEATWTMSNITAGRQD-QIQQVVNHGLVPFLVSVLSK--- 388

Query: 323 DGNVTVQHAALSALRNLAI--PVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRML 380
             +   Q  A+ A+ N      V     ++  G+ E ++  L ++   +   +L  +  +
Sbjct: 389 -ADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNI 447

Query: 381 IDAQAEAAEQLGKNVKLVERLVEWCEAKD 409
                +AAE+LG+  KL   ++E C   D
Sbjct: 448 F----QAAEKLGETEKL-SIMIEECGGLD 471


>gi|224589129 karyopherin 7 [Homo sapiens]
          Length = 516

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 64/311 (20%), Positives = 136/311 (43%), Gaps = 22/311 (7%)

Query: 86  VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQ 145
           V+ G I PL++LL+S +  V  Q   ALGNI  D    +  +I    IP L+ L+     
Sbjct: 153 VEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLLALIS---P 209

Query: 146 NAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFE---VLAPL 202
              +T +  + +  L+ L  +K  +      ++++      ++H   E++ +    L+ L
Sbjct: 210 TLPITFLRNITW-TLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALSYL 268

Query: 203 AENDAIKL-QLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLF 261
            +    ++ Q+V  G++  L+ ++     S+       L+T  +++      DE  Q   
Sbjct: 269 TDGSNKRIGQVVNTGVLPRLVVLM---TSSELNVLTPSLRTVGNIVTGT---DEQTQMAI 322

Query: 262 EGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHV 321
           + G  +V  ++L     N   +Q   A A++N A   A   H +   +   ++  L   +
Sbjct: 323 DAGMLNVLPQLLQ---HNKPSIQKEAAWALSNVA---AGPCHHIQQLLAYDVLPPLVALL 376

Query: 322 EDGNVTVQHAALSALRNLA--IPVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRM 379
           ++G   VQ  A+  + N A    +    +++ +GV E ++  L +    +   +L  +  
Sbjct: 377 KNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISC 436

Query: 380 LIDAQAEAAEQ 390
           ++ A  + +E+
Sbjct: 437 ILQAAEKRSEK 447


>gi|6912478 karyopherin alpha 6 [Homo sapiens]
          Length = 536

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 60/285 (21%), Positives = 118/285 (41%), Gaps = 21/285 (7%)

Query: 43  EKIQASGILQLFASLLTPQSSC--KAKVANIIAEVAKNEFMRIPCV-DAGLISPLVQLLN 99
           E I    ++  F   L    +C  + + A  +  +A     +   V +AG +   ++LLN
Sbjct: 118 EVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLN 177

Query: 100 SKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGN 159
           S  ++V  Q   ALGNI  DS   +  ++N  ++  L+ LL        +T   + A  N
Sbjct: 178 SDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLL-TKSTRLTMTRNAVWALSN 236

Query: 160 LAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQ-LVEAGLV 218
           L   ++   +FA  +    ++       + D        L+ L++    K+Q ++++G+ 
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVC 296

Query: 219 ECLLEIVQQ---KVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSW 275
             L+E++     KV S     +  + TG D+   ++L   ++  L            L  
Sbjct: 297 RRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL------------LHL 344

Query: 276 IPSNNHQLQLAGALAIANF-ARNDANCIHMVDNGIVEKLMDLLDR 319
           + S    ++      I+N  A N A    ++D  I   L+++L +
Sbjct: 345 LSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQK 389


>gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]
          Length = 493

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 4/161 (2%)

Query: 20  EDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP-QSSCKAKVANIIAEVAKN 78
           E   EG L  L + L    T+ +  I+  G ++    LLT  Q+  + + A  + E++ +
Sbjct: 80  EKEREGALVSLRRGLQHPETQQTF-IRLEGSMRTLVGLLTSNQALLQLEAARCLHELSHS 138

Query: 79  EFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVK 138
           E   +        S L+  L+S   + +      LGN+  +S +++ QL+  G++P L  
Sbjct: 139 EQSTVAEACLPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQGIVPALAA 198

Query: 139 LLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEEL 179
              I   + A+ E    A   L + E + E+   + +A  L
Sbjct: 199 C--IQSPHVAVLEALGYALSQLLQAEEAPEKIIPSILASTL 237


>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
          Length = 1363

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 94/471 (19%), Positives = 191/471 (40%), Gaps = 60/471 (12%)

Query: 94   LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLL-----GIHCQNAA 148
            LV++L  +  +  +    +L  IC  +      +++ G IP L+ LL      + C+   
Sbjct: 634  LVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVG 693

Query: 149  LTEMCLVAFGNLAELESSKEQFASTNIAEELVKLF--KKQIEHDKREMIFEVLAPLAEND 206
            L         N++  +S+            L+ L    +   H +  +I   +A     D
Sbjct: 694  L-------LSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHSRCAVILYDIAQCENKD 746

Query: 207  AIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKG 266
             I     +   +  L+ ++   +++        L    + + +L +G+E+ Q+     KG
Sbjct: 747  VI----AKYNGIPSLINLLNLNIEN-------VLVNVMNCIRVLCIGNENNQRAVREHKG 795

Query: 267  SVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVD-NGIVEKLMDLLDRHVEDGN 325
              +  ++ ++ S++  L+   + AIA   R++      +   G +  L+ L     +   
Sbjct: 796  LPY--LIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALF----KGKQ 849

Query: 326  VTVQHAALSALRNLAI--PVINKAKMLSAGVTEAVLKFLKSEMPPVQ----FKLLGTLRM 379
            ++VQ     A+ +LA    +I KA  L   +T+ +LK LK+    V+      L      
Sbjct: 850  ISVQMKGAMAVESLASHNALIQKA-FLEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQ 908

Query: 380  LIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQ 439
             +  Q   AEQ+G +  ++  L+       + G  GE+   LS   R  +++     I +
Sbjct: 909  TLKQQKYMAEQIGYSF-IINMLLSPSAKMQYVG--GEAVIALSKDSRMHQNQ-----ICE 960

Query: 440  SGGIKHLVTMATSEHVIMQNEALVALALIAALELGTA-------EKDLESAKLVQILHRL 492
              GI  LV +      I +   L  +  + ++ +G A       ++ +       +L +L
Sbjct: 961  GNGIAPLVRLLRIS-TIAEGTLLSVIRAVGSICIGVAHTSNPVSQQFVVDENAFPVLIQL 1019

Query: 493  LADERSAPEIKYN-SMVLICALMGSECLHKEVQD---LAFLDVVSKLRSHE 539
            L +  S P IK   +  L C ++G++ L K++ +     + DV+  L S E
Sbjct: 1020 LRNHPS-PNIKVEVAFSLACIVLGNDVLQKDLHENEGFEYADVLYLLHSTE 1069


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
           plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 11/130 (8%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++Q+L  +   V       L ++C+  + ++A++   G I  LV LL     +  +TE+ 
Sbjct: 555 VIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLL-----DHRMTEVH 609

Query: 154 LVAFGNLAEL------ESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDA 207
             A G L  L      + +K    +      LV+L +K  + + RE++  VL  L+  DA
Sbjct: 610 RSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDA 669

Query: 208 IKLQLVEAGL 217
           +K+ +++  L
Sbjct: 670 LKMPIIQDAL 679


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 29/129 (22%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLG---IHCQNAALT 150
           ++ +L  +   V       L ++C+  + ++ ++  +G I  LV LL    +  Q  A  
Sbjct: 533 VIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACG 592

Query: 151 EMCLVAFGNLAELESSKEQFASTNIA--EELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
            +  + FG      + + + A  N+     L++L +K I+ + RE++  VL  L+  DA+
Sbjct: 593 ALRNLVFGK----STDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAV 648

Query: 209 KLQLVEAGL 217
           K+ ++   L
Sbjct: 649 KMTIIRDAL 657


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 29/129 (22%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLG---IHCQNAALT 150
           ++ +L  +   V       L ++C+  + ++ ++  +G I  LV LL    +  Q  A  
Sbjct: 533 VIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACG 592

Query: 151 EMCLVAFGNLAELESSKEQFASTNIA--EELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
            +  + FG      + + + A  N+     L++L +K I+ + RE++  VL  L+  DA+
Sbjct: 593 ALRNLVFGK----STDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAV 648

Query: 209 KLQLVEAGL 217
           K+ ++   L
Sbjct: 649 KMTIIRDAL 657


>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
          Length = 1044

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 77/358 (21%), Positives = 136/358 (37%), Gaps = 47/358 (13%)

Query: 18   KTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVANIIAEVAK 77
            + E   E C   + Q     + ET + ++  G L+  ASLL    + K ++A +   + K
Sbjct: 685  ENEQLQEHCAMAIYQCA--EDKETRDLVRLHGGLKPLASLLNNTDN-KERLAAVTGAIWK 741

Query: 78   NEFMRIPCV---DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIP 134
                +       +   I  LV LL  + +EVL+    ALG  C +  +        G+ P
Sbjct: 742  CSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQP 801

Query: 135  TLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREM 194
             +  L+GI   N AL      A G  A +E              L+    K    D +  
Sbjct: 802  LVNLLVGI---NQALLVNVTKAVGACA-VEPESMMIIDRLDGVRLLWSLLKNPHPDVKAS 857

Query: 195  IFEVLAPLAEN--DA------------IKLQLVEAGLVECLLEIVQQKVDSDKEDDITEL 240
                L P  +N  DA            + + L+++   E L  +     +  K+ +   +
Sbjct: 858  AAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAV 917

Query: 241  KTGSDLMVLL-LLGDESMQKL------------------FEGGKGSVFQRVLSWIPSNNH 281
             T   ++ LL  L + +  KL                     G+      ++ ++ SN+ 
Sbjct: 918  ITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDT 977

Query: 282  QLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNL 339
             +  A A A+   + +  NCI M +NG V+ L+D++    +D    +Q AA   + N+
Sbjct: 978  NVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQD----LQEAAAGCISNI 1031



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 83/407 (20%), Positives = 149/407 (36%), Gaps = 60/407 (14%)

Query: 1   MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP 60
           +D   D+ K  + +  +  +  +  C    L + ++++T      +A GI  L   L T 
Sbjct: 585 LDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTS 644

Query: 61  QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS 120
             +    V   + E A  E  R       +I  LV+ LNS+++++      A+     D 
Sbjct: 645 HENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704

Query: 121 HSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKE---QFASTNIAE 177
            +     ++ G+ P L  LL     N    E      G + +   SKE   +F      E
Sbjct: 705 ETRDLVRLHGGLKP-LASLLN----NTDNKERLAAVTGAIWKCSISKENVTKFREYKAIE 759

Query: 178 ELVKLFKKQIEHDKREMIFEVLAPLAE------NDAI--------KLQLVEAGLVECLLE 223
            LV L   Q E    E++  V+  L E      N  I         L  +  G+ + LL 
Sbjct: 760 TLVGLLTDQPE----EVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLV 815

Query: 224 IVQQKVDSDKEDD----ITELKTGSDLMVLLLLGDE----------------------SM 257
            V + V +   +     I +   G  L+  LL                           M
Sbjct: 816 NVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEM 875

Query: 258 QKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLL 317
            + F GG     + +++ + S+N ++  +   AI N A++  N   + D+G+V     LL
Sbjct: 876 VRSFVGG----LELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVV----PLL 927

Query: 318 DRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKS 364
            +     N  ++H    A+    +   N+           ++++LKS
Sbjct: 928 SKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKS 974



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 33  ALAQNNTETSEKIQASGILQLFASLL-TPQSSCKAKVANIIAEVAKNEFMRIPCVDAGLI 91
           +LAQ   + +  I+  G L++  +LL T +  CK     I+ E++ N  +R   VD G +
Sbjct: 480 SLAQETCQLA--IRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGL 537

Query: 92  SPLVQLLNSKDQEVLLQTGRALGNI 116
             +V +L+S  + +       + N+
Sbjct: 538 PIMVNILDSPHKSLKCLAAETIANV 562


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 37.0 bits (84), Expect = 0.048
 Identities = 26/149 (17%), Positives = 67/149 (44%), Gaps = 2/149 (1%)

Query: 11  LKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKI-QASGILQLFASLLTPQSSCKAKVA 69
           L +  + + E +L+      L  +A+++ E ++ +  A  +  L   +L P +  K ++ 
Sbjct: 171 LLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQIL 230

Query: 70  NIIAEVAKNEF-MRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLI 128
           + +++V+K+   +    V+A +   ++  L  KD+ V       +  I   +  L   ++
Sbjct: 231 SALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVV 290

Query: 129 NMGVIPTLVKLLGIHCQNAALTEMCLVAF 157
           N G +  ++  +G    N  L  + ++ +
Sbjct: 291 NAGGVAAVIDCIGSCKGNTRLPGIMMLGY 319



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 421 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL 480
           LS + +HS   ++ +T+V +G + HL  M  +    ++++ L AL+ ++   +  AE  +
Sbjct: 191 LSDIAKHSP--ELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVV 248

Query: 481 ESAKLVQILHRLLADERSAPEIKYNSMVLI 510
           E A++  ++   L D+     +K N+  LI
Sbjct: 249 E-AEIFPVVLTCLKDKDE--YVKKNASTLI 275


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 37.0 bits (84), Expect = 0.048
 Identities = 26/149 (17%), Positives = 67/149 (44%), Gaps = 2/149 (1%)

Query: 11  LKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKI-QASGILQLFASLLTPQSSCKAKVA 69
           L +  + + E +L+      L  +A+++ E ++ +  A  +  L   +L P +  K ++ 
Sbjct: 171 LLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQIL 230

Query: 70  NIIAEVAKNEF-MRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLI 128
           + +++V+K+   +    V+A +   ++  L  KD+ V       +  I   +  L   ++
Sbjct: 231 SALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVV 290

Query: 129 NMGVIPTLVKLLGIHCQNAALTEMCLVAF 157
           N G +  ++  +G    N  L  + ++ +
Sbjct: 291 NAGGVAAVIDCIGSCKGNTRLPGIMMLGY 319



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 421 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL 480
           LS + +HS   ++ +T+V +G + HL  M  +    ++++ L AL+ ++   +  AE  +
Sbjct: 191 LSDIAKHSP--ELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVV 248

Query: 481 ESAKLVQILHRLLADERSAPEIKYNSMVLI 510
           E A++  ++   L D+     +K N+  LI
Sbjct: 249 E-AEIFPVVLTCLKDKDE--YVKKNASTLI 275


>gi|4504901 karyopherin alpha 4 [Homo sapiens]
          Length = 521

 Score = 37.0 bits (84), Expect = 0.048
 Identities = 66/320 (20%), Positives = 131/320 (40%), Gaps = 33/320 (10%)

Query: 34  LAQNNTETSEKIQASGILQLFASLLTPQS--SCKAKVANIIAEVAKNEFMRIPCVDAGLI 91
           L+ +     + +  SGIL +    L      S + + A  +  +A     +   V     
Sbjct: 99  LSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNA 158

Query: 92  SPL-VQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALT 150
            PL ++LL+S  Q V  Q   ALGNI  D    +  +I++GV+  L+  +        L 
Sbjct: 159 VPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLR 218

Query: 151 EMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPL-----AEN 205
            +  V    +  L   K+        +E++      I H    ++ + +  L     A N
Sbjct: 219 NVTWV----MVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGN 274

Query: 206 DAIKLQLVEAGLVECLLEIV---QQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFE 262
           + I++ ++++G+V  L+ ++   + KV +     +  + TG+D    ++L  +++     
Sbjct: 275 EQIQM-VIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDAL----- 328

Query: 263 GGKGSVFQRVLSWIPSNNHQLQLAGALAIANF-ARNDANCIHMVDNGIVEKLMDLLDRHV 321
               S F  +L+       ++       ++N  A N      ++D  +V  ++ LLD+  
Sbjct: 329 ----SHFPALLT---HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDK-- 379

Query: 322 EDGNVTVQHAALSALRNLAI 341
             G+   Q  A  A+ NL I
Sbjct: 380 --GDFGTQKEAAWAISNLTI 397


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 270 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 324

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 325 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 384

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 385 KMEIVDHALHALTDEVI 401


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 371 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 425

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 426 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 485

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 486 KMEIVDHALHALTDEVI 502


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 153
           ++ +L  +   V       L ++CY +  ++  +  +  IP LV LL     +    E+ 
Sbjct: 371 VIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVH 425

Query: 154 LVAFGNLAELESSKEQFASTNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAI 208
           L A G L  +   ++Q     I        LV+L +K  + D  E+I   L  L+ +D+I
Sbjct: 426 LGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSI 485

Query: 209 KLQLVEAGLVECLLEIV 225
           K+++V+  L     E++
Sbjct: 486 KMEIVDHALHALTDEVI 502


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,691,060
Number of Sequences: 37866
Number of extensions: 633448
Number of successful extensions: 2150
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1991
Number of HSP's gapped (non-prelim): 122
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.