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Search of human proteins with 154426312
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154426312 SPATS2-like protein isoform b [Homo sapiens]
(489 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154426312 SPATS2-like protein isoform b [Homo sapiens] 972 0.0
gi|154426288 SPATS2-like protein isoform a [Homo sapiens] 802 0.0
gi|154426253 SPATS2-like protein isoform a [Homo sapiens] 802 0.0
gi|154426310 SPATS2-like protein isoform a [Homo sapiens] 802 0.0
gi|148746220 spermatogenesis associated, serine-rich 2 [Homo sap... 300 2e-81
gi|47578107 delangin isoform B [Homo sapiens] 47 5e-05
gi|47578105 delangin isoform A [Homo sapiens] 47 5e-05
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 43 7e-04
gi|45439327 periplakin [Homo sapiens] 43 7e-04
gi|70980549 programmed cell death 11 [Homo sapiens] 42 0.002
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.004
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 40 0.004
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 40 0.005
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 40 0.006
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.008
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 39 0.011
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 39 0.014
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 39 0.014
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 39 0.014
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.014
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 39 0.014
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 39 0.014
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 39 0.014
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 39 0.014
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 39 0.014
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 37 0.031
gi|21264343 scaffold attachment factor B [Homo sapiens] 37 0.053
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 37 0.053
gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens] 37 0.053
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 37 0.053
>gi|154426312 SPATS2-like protein isoform b [Homo sapiens]
Length = 489
Score = 972 bits (2512), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
ANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM
Sbjct: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSS 300
QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSS
Sbjct: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSS 300
Query: 301 LLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNG 360
LLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNG
Sbjct: 301 LLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNG 360
Query: 361 SSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKN 420
SSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKN
Sbjct: 361 SSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKN 420
Query: 421 QEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVL 480
QEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVL
Sbjct: 421 QEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVL 480
Query: 481 SVPAVTLVA 489
SVPAVTLVA
Sbjct: 481 SVPAVTLVA 489
>gi|154426288 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 802 bits (2071), Expect = 0.0
Identities = 432/558 (77%), Positives = 450/558 (80%), Gaps = 69/558 (12%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTGPN--------IEKSVKDL------------- 159
ANEKPALIPREKKISILEEPSKALRGVT N ++ + K +
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
Query: 160 --QRCTVSLTRYRVM----------IKEEVDSSVKK----IKAAFAELHNCIID---KEV 200
Q C S + + ++ + D KK I+ + +L C + V
Sbjct: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Query: 201 SLMAEMD----KVKEEAMEI----------LTARQKKAEE---------------LKRLT 231
+ E+D K+K E+ L A K +E LKRLT
Sbjct: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
Query: 232 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 291
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
Query: 292 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 351
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
Query: 352 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 411
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
Query: 412 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 471
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
Query: 472 EVSTDAAVLSVPAVTLVA 489
EVSTDAAVLSVPAVTLVA
Sbjct: 541 EVSTDAAVLSVPAVTLVA 558
>gi|154426253 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 802 bits (2071), Expect = 0.0
Identities = 432/558 (77%), Positives = 450/558 (80%), Gaps = 69/558 (12%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTGPN--------IEKSVKDL------------- 159
ANEKPALIPREKKISILEEPSKALRGVT N ++ + K +
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
Query: 160 --QRCTVSLTRYRVM----------IKEEVDSSVKK----IKAAFAELHNCIID---KEV 200
Q C S + + ++ + D KK I+ + +L C + V
Sbjct: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Query: 201 SLMAEMD----KVKEEAMEI----------LTARQKKAEE---------------LKRLT 231
+ E+D K+K E+ L A K +E LKRLT
Sbjct: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
Query: 232 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 291
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
Query: 292 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 351
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
Query: 352 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 411
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
Query: 412 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 471
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
Query: 472 EVSTDAAVLSVPAVTLVA 489
EVSTDAAVLSVPAVTLVA
Sbjct: 541 EVSTDAAVLSVPAVTLVA 558
>gi|154426310 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 802 bits (2071), Expect = 0.0
Identities = 432/558 (77%), Positives = 450/558 (80%), Gaps = 69/558 (12%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTGPN--------IEKSVKDL------------- 159
ANEKPALIPREKKISILEEPSKALRGVT N ++ + K +
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
Query: 160 --QRCTVSLTRYRVM----------IKEEVDSSVKK----IKAAFAELHNCIID---KEV 200
Q C S + + ++ + D KK I+ + +L C + V
Sbjct: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Query: 201 SLMAEMD----KVKEEAMEI----------LTARQKKAEE---------------LKRLT 231
+ E+D K+K E+ L A K +E LKRLT
Sbjct: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
Query: 232 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 291
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
Query: 292 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 351
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
Query: 352 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 411
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
Query: 412 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 471
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
Query: 472 EVSTDAAVLSVPAVTLVA 489
EVSTDAAVLSVPAVTLVA
Sbjct: 541 EVSTDAAVLSVPAVTLVA 558
>gi|148746220 spermatogenesis associated, serine-rich 2 [Homo
sapiens]
Length = 545
Score = 300 bits (769), Expect = 2e-81
Identities = 205/526 (38%), Positives = 284/526 (53%), Gaps = 86/526 (16%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
+A+ N+KEKI AVR++VPNKSNNEI+LVLQ FD VDK VQAF++GSA +VLKEW
Sbjct: 23 LAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWT 82
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGP----MNGCEKDSS 116
+TGKKKN K+K + + D + Q P + G +NG D+
Sbjct: 83 VTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTE 142
Query: 117 STDSAN----------------EKPALIPREKKISILE--------------------EP 140
S DS + E L ++ S+L+ +P
Sbjct: 143 SVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQP 202
Query: 141 SKALRGVTGP------------------------NIEKSVKDLQRCTVSLTRYRVMIKEE 176
A + ++ P NIEKSVKDLQRCTVSL RYRV++KEE
Sbjct: 203 RNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEE 262
Query: 177 VDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQ 236
+D+S+KK+K AFAEL +C++D+EV+L+AEMDKVK EAMEIL +RQKKAE LK++T +A Q
Sbjct: 263 MDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQ 322
Query: 237 MAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRT 296
M+E QL ELRA+IKHFVSERKYDE+LG+ ARF+CD+E LK I G+++HPKN+YS+R+
Sbjct: 323 MSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSHPKNSYSTRS 382
Query: 297 PCSSLLPL-----LNAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMVSSLPSTADP 348
CSS+ + +A AA+S ++ +S + K P E AA + +S P
Sbjct: 383 RCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IANSSGQPYQP 439
Query: 349 SHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNSRHEH--RRQ 405
+ +P N++ G Q R Q N+ +N G S G + G SR++ +
Sbjct: 440 LREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-SRYQSAPSQA 495
Query: 406 PHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADT 448
P N A + M+ P P S K P+R+ + T
Sbjct: 496 PGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQT 540
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 46.6 bits (109), Expect = 5e-05
Identities = 89/409 (21%), Positives = 155/409 (37%), Gaps = 83/409 (20%)
Query: 89 ERPEAGPLQPQPPQIQNGPM-NGCEKDSSSTDSANEKPALIPREKKISILEEPSKALR-- 145
++P+ +Q Q Q GP+ + E D+ + E+ + I RE+ +++ K L+
Sbjct: 446 KQPQTSVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKR 505
Query: 146 ----------GVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCI 195
G TG N S + T + +R +M+ ++ + +
Sbjct: 506 KQDSYPQEAGGATGGNRPASQET--GSTGNGSRPALMVSIDLHQAGR------------- 550
Query: 196 IDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDL-ASQMAEMQLAELRAEIKHF-- 252
+D + S+ + D +K K EE+K+ D S + E + L++ ++
Sbjct: 551 VDSQASITQDSDSIK------------KPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPE 598
Query: 253 VSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATS 312
++K D EL K+ +++Q ++++ + P N T S T
Sbjct: 599 TPKKKSDPELSKS-----EMKQSESRLAE----SKPNENRLVETKSSENKLETKVETQTE 649
Query: 313 GKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNP-- 370
+ N SR +T K +E PK + S P+ NKQN ++ + P
Sbjct: 650 ELKQNESR--TTECKQNESTIVEPKQNENRLSDTKPND-----NKQNNGRSETTKSRPET 702
Query: 371 --QYHNNRLNGPA----------KSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGA 418
Q +R P K +G G P KG SR E +Q + G RP+
Sbjct: 703 PKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEG-RPETPKHR 761
Query: 419 KNQEASLGM----KTPEAPAH-----SEKPRRRQHAADTSEARPFRGSV 458
+ G K PE H S+ PR + A+ + RP SV
Sbjct: 762 HDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV 810
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 46.6 bits (109), Expect = 5e-05
Identities = 89/409 (21%), Positives = 155/409 (37%), Gaps = 83/409 (20%)
Query: 89 ERPEAGPLQPQPPQIQNGPM-NGCEKDSSSTDSANEKPALIPREKKISILEEPSKALR-- 145
++P+ +Q Q Q GP+ + E D+ + E+ + I RE+ +++ K L+
Sbjct: 446 KQPQTSVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKR 505
Query: 146 ----------GVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCI 195
G TG N S + T + +R +M+ ++ + +
Sbjct: 506 KQDSYPQEAGGATGGNRPASQET--GSTGNGSRPALMVSIDLHQAGR------------- 550
Query: 196 IDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDL-ASQMAEMQLAELRAEIKHF-- 252
+D + S+ + D +K K EE+K+ D S + E + L++ ++
Sbjct: 551 VDSQASITQDSDSIK------------KPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPE 598
Query: 253 VSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATS 312
++K D EL K+ +++Q ++++ + P N T S T
Sbjct: 599 TPKKKSDPELSKS-----EMKQSESRLAE----SKPNENRLVETKSSENKLETKVETQTE 649
Query: 313 GKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNP-- 370
+ N SR +T K +E PK + S P+ NKQN ++ + P
Sbjct: 650 ELKQNESR--TTECKQNESTIVEPKQNENRLSDTKPND-----NKQNNGRSETTKSRPET 702
Query: 371 --QYHNNRLNGPA----------KSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGA 418
Q +R P K +G G P KG SR E +Q + G RP+
Sbjct: 703 PKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEG-RPETPKHR 761
Query: 419 KNQEASLGM----KTPEAPAH-----SEKPRRRQHAADTSEARPFRGSV 458
+ G K PE H S+ PR + A+ + RP SV
Sbjct: 762 HDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV 810
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 42.7 bits (99), Expect = 7e-04
Identities = 53/239 (22%), Positives = 104/239 (43%), Gaps = 18/239 (7%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEK-DSSSTDSAN 122
+ K N+R+ S+S+ N + E P I ++ D
Sbjct: 45 ESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEE 104
Query: 123 EKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVK 182
EK A R++KI E K + T +E+ V +R L + + I+ EV V+
Sbjct: 105 EKKAEFERQRKIRQQEIEEKLIEEETARRVEELVA--KRVEEELEKRKDEIEREVLRRVE 162
Query: 183 KIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQK----KAEELKRLTDLASQ-M 237
+ K I++K+ L+ E+++ ++ + AR++ K EEL+R+ + ++ +
Sbjct: 163 EAKR--------IMEKQ--LLEELERQRQAELAAQKAREEEERAKREELERILEENNRKI 212
Query: 238 AEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRT 296
AE Q +++ +RK EE K + ++ + +I+L + PK ++S +T
Sbjct: 213 AEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKT 271
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 42.7 bits (99), Expect = 7e-04
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 18/188 (9%)
Query: 104 QNGPMNGCEKDSSSTDSANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCT 163
Q G E+ S S E AL R ++ + E + ++ T P +EK ++ L+
Sbjct: 1198 QERKYRGAEEQLRSYQS--ELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEI 1255
Query: 164 VSLTRYRVMIKEEVDSSVKKIKA---AFAELHNCIIDKEVSLMAEMDKVKEEAMEILTAR 220
V TR E+ K+I+A ++ + +E+ E + KE E+ + R
Sbjct: 1256 VDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKE---EVASLR 1312
Query: 221 QKKAEELKRLTDLASQMA--EMQLAELRAEIKHFVSER-------KYDEELGKAARFSCD 271
K +EE K+ DL + A E Q+A E+ V ER +Y+EE G A S
Sbjct: 1313 AKLSEEQKKQVDLERERASQEEQIARKEEELSR-VKERVVQQEVVRYEEEPGLRAEASAF 1371
Query: 272 IEQLKAQI 279
E + ++
Sbjct: 1372 AESIDVEL 1379
Score = 30.8 bits (68), Expect = 2.9
Identities = 30/127 (23%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 142 KALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVS 201
+ L+ V P +E+S + LQR +++EE+++ +++A E + + V
Sbjct: 936 EVLKKVPDPVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVK 995
Query: 202 LMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELR----AEIKHFVSERK 257
+ ++ + +A E+L R+ + E L+R ++ AE+ L + R AE K E+
Sbjct: 996 EVLRIEPDRAQADEVLQLRE-ELEALRR--QKGAREAEVLLLQQRVAALAEEKSRAQEKV 1052
Query: 258 YDEELGK 264
++E+ K
Sbjct: 1053 TEKEVVK 1059
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 12/83 (14%)
Query: 57 KEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSS 116
+E + G+KKN KR K N+ +++VE P QPQ PQ Q C + S
Sbjct: 1425 EERDQKGEKKNQKRNEKK------NQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGS 1478
Query: 117 STDSANEKPALIPREKKISILEE 139
+ ++KP KK + EE
Sbjct: 1479 EQERVSKKP------KKAGLSEE 1495
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.4 bits (93), Expect = 0.004
Identities = 64/286 (22%), Positives = 116/286 (40%), Gaps = 46/286 (16%)
Query: 3 ELNTHVNVKEKIYAVRSVVPNKSNNEIVLV--LQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
+L +++ EK A+ S+ + L+ +Q F VD + + SA++ + +W+
Sbjct: 1382 QLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKI--SALEQVDDWS 1439
Query: 61 MTGKKKNNKRKRSKSKQHQGNKD---------AKDKVERPEAGPLQPQPPQIQNGPMNGC 111
+ K+ +S+ QHQ +K+ E+ E L + QN + C
Sbjct: 1440 NKFSEWK-KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFD-C 1497
Query: 112 EKDSSSTDSANEKPALIPREKKISILEEPSKALRG--------VTGPNIE---------- 153
K D + EKK S LE K+ +T IE
Sbjct: 1498 LKGEMEDDKSK-------MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1550
Query: 154 -KSVKDLQ-RCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKE 211
KD++ + V ++ + EE D+ VK+ + L N + S+ AE++ K+
Sbjct: 1551 YNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVY----SMKAELETKKK 1606
Query: 212 EAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERK 257
E + + + K EELK L D + +LAEL+ + + ++ K
Sbjct: 1607 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK 1652
Score = 34.3 bits (77), Expect = 0.26
Identities = 29/125 (23%), Positives = 61/125 (48%), Gaps = 16/125 (12%)
Query: 152 IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKE 211
+EK++ Q+ + R +K E+D +K I+ E + +SL E+ +VK+
Sbjct: 416 LEKALSTAQKTEEA----RRKLKAEMDEQIKTIEKTSEE-------ERISLQQELSRVKQ 464
Query: 212 EAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCD 271
E ++++ ++ E++ +L L + + EL +++ ER++ E++ K A
Sbjct: 465 EVVDVM--KKSSEEQIAKLQKLHEKELARKEQELTKKLQ--TREREFQEQM-KVALEKSQ 519
Query: 272 IEQLK 276
E LK
Sbjct: 520 SEYLK 524
Score = 32.3 bits (72), Expect = 1.0
Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 4/96 (4%)
Query: 160 QRCTVSLTRYRVMIKEEVDSSVKK----IKAAFAELHNCIIDKEVSLMAEMDKVKEEAME 215
Q+ + + R ++E ++ +K +A E++ ++K E++ + E E
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE 695
Query: 216 ILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKH 251
+L AR K EEL L D +M + A++ + H
Sbjct: 696 VLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNH 731
Score = 31.2 bits (69), Expect = 2.2
Identities = 46/251 (18%), Positives = 105/251 (41%), Gaps = 21/251 (8%)
Query: 130 REKKISILEEPSKALRGVTGPNI----EKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIK 185
+EKK+ +++ +K ++ + K K+L+ + L++ ++ +
Sbjct: 952 QEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANS 1011
Query: 186 AAFAELHNCIIDKEVSLMAEMDKV-KEEAMEILTARQKK----AEELKRLTDLASQMAEM 240
A ++ + + + + + +V + E ++++ +KK AEEL+ + ++ Q E
Sbjct: 1012 AGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQ 1071
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARF------SCDIEQLKAQIMLCGEITHPKNNYSS 294
++AEL+ +I F E+ EE+ K + D + Q L + H +
Sbjct: 1072 EVAELKQKILLFGCEK---EEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD 1128
Query: 295 RTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNK--PSEGKAANPKMVSSLPSTADPSHQT 352
T + L L S K++ F ++ K E K ++ S L T D Q+
Sbjct: 1129 ETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKL-KTTDEEFQS 1187
Query: 353 MPANKQNGSSN 363
+ ++ + + +
Sbjct: 1188 LKSSHEKSNKS 1198
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 40.4 bits (93), Expect = 0.004
Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 30/192 (15%)
Query: 112 EKDSSST-DSANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYR 170
EK+ + T D NE + R K++ E +EK+ L+ L +
Sbjct: 457 EKEKNLTKDLLNELEVVKSRVKELECSES-----------RLEKAELSLKDDLTKLKSFT 505
Query: 171 VMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL 230
VM+ +E + ++KIK +++V + + KV++ +++ +K EE K+L
Sbjct: 506 VMLVDERKNMMEKIKQE---------ERKVDGLNKNFKVEQG--KVMDVTEKLIEESKKL 554
Query: 231 TDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI----MLCGEIT 286
L S+M E ++ L E + + K +EE K++ SC ++ LK ++ + EIT
Sbjct: 555 LKLKSEMEE-KVYNLTRERDELIGKLKSEEE--KSSELSCSVDLLKKRLDGIEEVEREIT 611
Query: 287 HPKNNYSSRTPC 298
++ S C
Sbjct: 612 RGRSRKGSELTC 623
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 40.0 bits (92), Expect = 0.005
Identities = 56/246 (22%), Positives = 112/246 (45%), Gaps = 32/246 (13%)
Query: 131 EKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAE 190
EK +I++E ++ ++ ++ N E+ +K+ ++ + +++ +E KIK E
Sbjct: 1218 EKLKTIMKENTELVQKLS--NYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTL--E 1273
Query: 191 LHNCIID---KEVSLMAEMDKVKE-EAMEILTARQKKAEELKRLTDL-ASQMAEMQLAEL 245
+ I+D K + +M E ++ + + ++++ +K E+LK + + AS+ +E+Q+A
Sbjct: 1274 KNQEILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALN 1333
Query: 246 RAEIK--------HFVSE-----RKYDEELGKA--------ARFSCDIEQL-KAQIMLCG 283
A++ H V E +K E+L + A S I+ K+Q L
Sbjct: 1334 EAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEV 1393
Query: 284 EITHPKNNYSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLP 343
+TH +N ++ T C + L LL + + G Q+ S G N KM + +
Sbjct: 1394 ALTHKDDNINALTNCITQLNLLECESESEG-QNKGGNDSDELANGEVGGDRNEKMKNQIK 1452
Query: 344 STADPS 349
D S
Sbjct: 1453 QMMDVS 1458
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 39.7 bits (91), Expect = 0.006
Identities = 45/225 (20%), Positives = 97/225 (43%), Gaps = 15/225 (6%)
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTD- 119
+TG+ +N+ +R K Q + + ++ E ++ + + EKD D
Sbjct: 420 LTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHK------EKDHLVNDY 473
Query: 120 SANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDS 179
N K + I++L++ IE+ +++ + L + K+++
Sbjct: 474 EQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRD 533
Query: 180 SVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEIL----TARQKKAEELKRLTD--- 232
K + + L + K L +E+DK KE+ + + A ++K E+L R+T+
Sbjct: 534 QENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQR 593
Query: 233 LASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKA 277
L +Q A+ L E + +++ SE+ Y E + + D+ + K+
Sbjct: 594 LQAQQADAALEEFKRQVE-LNSEKVYAEMKEQMEKVEADLTRSKS 637
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 39.3 bits (90), Expect = 0.008
Identities = 47/205 (22%), Positives = 90/205 (43%), Gaps = 20/205 (9%)
Query: 54 QVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEK 113
+V KE + T K N + + + +K K+K EA Q++ +NG K
Sbjct: 967 KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIK 1026
Query: 114 DSSSTDS-ANEKPALIPREKKISI-LEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRV 171
++ + ++ + +EKK+ LE + L G + ++S+ DL+
Sbjct: 1027 INAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMS-QESIMDLEND--------- 1076
Query: 172 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 231
K++++ +KK + ++L I D++V + K+KE L AR ++ EE
Sbjct: 1077 --KQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKE-----LQARIEELEEEIEAE 1129
Query: 232 DLASQMAEMQLAELRAEIKHFVSER 256
E Q ++L E++ +SER
Sbjct: 1130 HTLRAKIEKQRSDLARELEE-ISER 1153
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 38.9 bits (89), Expect = 0.011
Identities = 62/267 (23%), Positives = 109/267 (40%), Gaps = 34/267 (12%)
Query: 33 LQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPE 92
+Q F+ D D SA +VLK K +K + K K+ + K RP+
Sbjct: 94 IQVFEDGADTTSPETPDSSASKVLKREGTDTTAKTSKLRGLKPKKAPTAR--KTTTRRPK 151
Query: 93 AGPLQPQPPQIQ--------NGPMNGCEKDSSSTDSANEKPALIP--------REKKISI 136
P +P + +G + E SS + + P P +
Sbjct: 152 --PTRPASTGVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPP 209
Query: 137 LEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVK-KIKAA-FAELHNC 194
L PSK G + V+DL+ +L R K ++ K KI+ E +
Sbjct: 210 LPSPSKEEEG-----LRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSK 264
Query: 195 IIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM--QLAELRAEIKHF 252
+ +++ L + + ++EA E L A+++ EE+ D A +MA + ++AE RAE
Sbjct: 265 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTAD-AIEMATLDKEMAEERAESL-- 321
Query: 253 VSERKYDEELGKAARFSCDIEQLKAQI 279
+++ + + + D+E LKA+I
Sbjct: 322 --QQEVEALKERVDELTTDLEILKAEI 346
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 38.5 bits (88), Expect = 0.014
Identities = 53/229 (23%), Positives = 102/229 (44%), Gaps = 41/229 (17%)
Query: 74 KSKQHQGNKDAKDKVERPEAGPLQPQPPQIQN-GPMNGCEKDSSSTDSANEKPALIPREK 132
K K Q ++ ++++E E+ + Q ++ + E++ + N K A +EK
Sbjct: 938 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLA---KEK 994
Query: 133 KI------------SILEEPSKALRGVTGPNIEKSVKDL---------QRCTVSLTRYRV 171
K+ + EE SK+L + + E + DL QR + TR ++
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKH-EAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 172 M-IKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL 230
++ + +++A AEL + KE L A + +V+EEA + K LK++
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ-------KNMALKKI 1106
Query: 231 TDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
+L SQ++E+Q +L +E K +LG+ ++E LK ++
Sbjct: 1107 RELESQISELQ-EDLESERASRNKAEKQKRDLGE------ELEALKTEL 1148
Score = 31.6 bits (70), Expect = 1.7
Identities = 37/163 (22%), Positives = 73/163 (44%), Gaps = 23/163 (14%)
Query: 112 EKDSSSTDSANE--KPALIPREKKISILEEPSKALRGVT---GPNIEKSVKDLQRCTVSL 166
E+D D +E K L+ + +++ E + R + +E +KDL+ S
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629
Query: 167 TRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEE 226
+ R D ++K+++ A++ +C M E+D + EIL A+ K+ E
Sbjct: 1630 NKNR-------DEAIKQLRKLQAQMKDC--------MRELDDTRASREEIL-AQAKENE- 1672
Query: 227 LKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFS 269
K+L + ++M ++Q AE ++++ DE + A S
Sbjct: 1673 -KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSS 1714
Score = 29.6 bits (65), Expect = 6.5
Identities = 37/179 (20%), Positives = 69/179 (38%), Gaps = 25/179 (13%)
Query: 67 NNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPA 126
N++ K++ + Q N D + + Q + QN + ++ T + K +
Sbjct: 1749 NDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKAS 1808
Query: 127 LIPREKKISILEEP--------SKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVD 178
+ E KI+ LEE A + V EK +KD+ R K++ D
Sbjct: 1809 ITALEAKIAQLEEQLDNETKERQAACKQVR--RTEKKLKDVLLQVDDERRNAEQYKDQAD 1866
Query: 179 SSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQM 237
+ ++K L ++++ +EEA +R+K EL+ T+ A M
Sbjct: 1867 KASTRLK---------------QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1726
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1727 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1777
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1778 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1837
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1838 KLAAIGEATRLK 1849
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2136 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2195
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2196 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2247
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2250 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2303
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2304 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2355
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2356 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2389
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1611 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1670
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1671 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1730
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1731 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1781
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1782 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1841
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1842 KLAAIGEATRLK 1853
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2140 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2199
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2200 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2251
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2254 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2307
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2308 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2359
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2360 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2393
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1726
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1727 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1777
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1778 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1837
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1838 KLAAIGEATRLK 1849
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2136 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2195
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2196 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2247
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2250 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2303
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2304 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2355
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2356 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2389
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1575 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1634
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1635 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1694
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1695 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1745
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1746 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1805
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1806 KLAAIGEATRLK 1817
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2104 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2163
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2164 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2215
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2218 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2271
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2272 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2323
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2324 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2357
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1744 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1803
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1804 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1863
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1864 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1914
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1915 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1974
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1975 KLAAIGEATRLK 1986
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2273 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2332
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2333 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2384
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2387 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2440
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2441 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2492
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2493 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2526
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1585 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1644
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1645 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1704
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1705 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1755
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1756 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1815
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1816 KLAAIGEATRLK 1827
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2114 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2173
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2174 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2225
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2228 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2281
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2282 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2333
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2334 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2367
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1593 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1652
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1653 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1712
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1713 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1763
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1764 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1823
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1824 KLAAIGEATRLK 1835
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2122 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2181
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2182 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2233
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2236 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2289
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2290 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2341
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2342 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2375
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 38.5 bits (88), Expect = 0.014
Identities = 60/252 (23%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDKVER-----PEAGPLQPQPPQI-QNGPMNGCEKDSSS 117
+++ +R + +++ + ++A+ ++ER EA L+ Q ++ Q + E +
Sbjct: 1634 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693
Query: 118 TDSANE--------KPALIPREKKISILEEPSKALRGVTGPNI--EKSVKDLQRCTVSLT 167
++ E + A+ RE LE+ + G + E+ + L+ T
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1753
Query: 168 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 227
+ R +++EE+ ++ AA K L AE+ KV+ E ME+L A + +AEE
Sbjct: 1754 QQRQLLEEELARLQREAAAA--------TQKRQELEAELAKVRAE-MEVLLASKARAEEE 1804
Query: 228 KRLTDLASQM---AE----MQLAELRAEIKHFVSERKYDEELGK--AARFSCDIEQLKAQ 278
R T S+ AE +LAE A ++ E K +L + AAR + E++ A+
Sbjct: 1805 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1864
Query: 279 -IMLCGEITHPK 289
+ GE T K
Sbjct: 1865 KLAAIGEATRLK 1876
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 175 EEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRL---- 230
E++ ++ A A+ + ++ + AEM+K K+ A + L + + +EL L
Sbjct: 2163 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQL 2222
Query: 231 --TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKAARFSCDIEQLKAQI 279
TD + + +L L+AE +R + +EEL ++ +LKA+I
Sbjct: 2223 EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2274
Score = 29.6 bits (65), Expect = 6.5
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 123 EKPALIPREKKIS--ILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 180
E ALI R+K + L+E ++ ++ V SV R R + +E++
Sbjct: 2277 ENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-----AAQEAARLRQLAEEDLAQ- 2330
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 240
+ A AE ++ +++ + E ++K EA + ++ E+ +RL + QMA+
Sbjct: 2331 ----QRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ- 2382
Query: 241 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 279
QLAE E + F +R + E + S + E+LK ++
Sbjct: 2383 QLAE---ETQGF--QRTLEAERQRQLEMSAEAERLKLRV 2416
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 37.4 bits (85), Expect = 0.031
Identities = 59/258 (22%), Positives = 103/258 (39%), Gaps = 26/258 (10%)
Query: 38 FNVDKAVQAFVDGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGN----KDAKDKVERPEA 93
F D+ FV S IQV ++ T + SK + +G K +K
Sbjct: 79 FTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGTDTTAKTSKLPTRPAST 138
Query: 94 GPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIP--------REKKISILEEPSKALR 145
G +G + E SS + + P P + L PSK
Sbjct: 139 GVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEE 198
Query: 146 GVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVK-KIKAA-FAELHNCIIDKEVSLM 203
G + V+DL+ +L R K ++ K KI+ E + + +++ L
Sbjct: 199 G-----LRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 253
Query: 204 AEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM--QLAELRAEIKHFVSERKYDEE 261
+ + ++EA E L A+++ EE+ D A +MA + ++AE RAE +++ +
Sbjct: 254 RRLKEARKEAKEALEAKERYMEEMADTAD-AIEMATLDKEMAEERAESL----QQEVEAL 308
Query: 262 LGKAARFSCDIEQLKAQI 279
+ + D+E LKA+I
Sbjct: 309 KERVDELTTDLEILKAEI 326
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 36.6 bits (83), Expect = 0.053
Identities = 53/245 (21%), Positives = 103/245 (42%), Gaps = 37/245 (15%)
Query: 50 GSAIQVLKEWNM-TGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPM 108
G I V K N GKK ++KR K+ N D ++R + + + +G
Sbjct: 474 GKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDG-- 531
Query: 109 NGCEKDSSSTDSANEKPALIPREK---------KISILEEPSKALRGV---TGPNIEKSV 156
S D ++KP R + + +++ + SK + + T + E++
Sbjct: 532 ----SGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERAS 587
Query: 157 KDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCI---IDKEVSLMAEMDKVKEEA 213
K R + S + V+ D + K+ +E H+ + ++E + A+ ++ + E
Sbjct: 588 KSQDRKSASREKRSVV---SFDKVKEPRKSRDSESHSRVRERSEREQRMQAQWEREERER 644
Query: 214 MEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIE 273
+EI AR++ A + +RL + M+ L E H ER+ ++E R + E
Sbjct: 645 LEI--ARERLAFQRQRL-----ERERMERERLERERMHVEHERRREQE-----RIHRERE 692
Query: 274 QLKAQ 278
+L+ Q
Sbjct: 693 ELRRQ 697
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 36.6 bits (83), Expect = 0.053
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 15/104 (14%)
Query: 64 KKKNNKRKRSKSKQHQGNKDAKDK-----VERPEA-------GPLQPQPPQIQNGPMNGC 111
K+K +K+K ++ +HQ + + K +++ EA PL+PQ P+ Q + G
Sbjct: 1692 KEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVIGS 1751
Query: 112 EKD---SSSTDSANEKPALIPREKKISILEEPSKALRGVTGPNI 152
E+ S S+ S+ + P + K+S + S L G+TG ++
Sbjct: 1752 ERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADV 1795
>gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]
Length = 822
Score = 36.6 bits (83), Expect = 0.053
Identities = 54/236 (22%), Positives = 93/236 (39%), Gaps = 60/236 (25%)
Query: 41 DKAVQAFV-DGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDA-KDKVERPEAGPLQP 98
DK +Q + D A Q +E N KKK K+ + KQ +G K+ K++ E+ + P
Sbjct: 332 DKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLF 391
Query: 99 QPPQIQNGPMNGC--------EKDSSSTDSANEKPALIPREKKISILEEPSKALRGVTGP 150
P GC +KD S S + P LI EK+
Sbjct: 392 LPAM-----KEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKR----------------- 429
Query: 151 NIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVK 210
K+LQ + R+ + E + +K +K A +D+E + K K
Sbjct: 430 ------KELQ------SEIRIQVDELMRQELKNLKLA--------VDRERERPVKAGKKK 469
Query: 211 EEAMEILTARQKKAEELKRLT------DLASQMAE--MQLAELRAEIKHFVSERKY 258
++ + ++KKA++ K LT L ++ E + + L+ + ++ E Y
Sbjct: 470 DKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALKVNLSDYIGEYSY 525
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 36.6 bits (83), Expect = 0.053
Identities = 49/193 (25%), Positives = 83/193 (43%), Gaps = 28/193 (14%)
Query: 74 KSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIPRE-- 131
K + H+ + AK+K ER E + Q Q +NG + + +S ++A EK + E
Sbjct: 613 KRQLHRDLEQAKEKGERAEKLERELQRLQEENGRL---ARKVTSLETATEKVEALEHESQ 669
Query: 132 ----------KKISILEEPSKALRGVTGPNIEKSVKDLQ-RCTVSLTRYRVMIKEEVDSS 180
K + L+ S L G+ N + ++L+ R V R+ +++
Sbjct: 670 GLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERE 729
Query: 181 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLAS----- 235
++++ EL K V L+ + K K E +E L+ + AE L+ L S
Sbjct: 730 NQQLEREKEELR-----KNVDLLKALGK-KSERLE-LSYQSVSAENLRLQQSLESSSHKT 782
Query: 236 QMAEMQLAELRAE 248
Q E +L EL AE
Sbjct: 783 QTLESELGELEAE 795
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,979,348
Number of Sequences: 37866
Number of extensions: 934163
Number of successful extensions: 5185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 332
Number of HSP's that attempted gapping in prelim test: 4744
Number of HSP's gapped (non-prelim): 814
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.