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Search of human proteins with 154426253
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154426253 SPATS2-like protein isoform a [Homo sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154426288 SPATS2-like protein isoform a [Homo sapiens] 1113 0.0
gi|154426253 SPATS2-like protein isoform a [Homo sapiens] 1113 0.0
gi|154426310 SPATS2-like protein isoform a [Homo sapiens] 1113 0.0
gi|154426312 SPATS2-like protein isoform b [Homo sapiens] 802 0.0
gi|148746220 spermatogenesis associated, serine-rich 2 [Homo sap... 322 4e-88
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 45 1e-04
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 45 2e-04
gi|70980549 programmed cell death 11 [Homo sapiens] 44 5e-04
gi|47578107 delangin isoform B [Homo sapiens] 44 5e-04
gi|47578105 delangin isoform A [Homo sapiens] 44 5e-04
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 41 0.003
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 40 0.006
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 39 0.016
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 39 0.016
gi|156104908 myosin heavy chain 6 [Homo sapiens] 39 0.016
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 38 0.021
gi|110349719 titin isoform N2-A [Homo sapiens] 38 0.028
gi|110349717 titin isoform novex-2 [Homo sapiens] 38 0.028
gi|110349713 titin isoform novex-1 [Homo sapiens] 38 0.028
gi|110349715 titin isoform N2-B [Homo sapiens] 38 0.028
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 38 0.028
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 38 0.028
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 38 0.028
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 38 0.028
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 38 0.028
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 38 0.028
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 38 0.028
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 38 0.028
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 38 0.028
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 37 0.037
>gi|154426288 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 1113 bits (2879), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
Query: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV
Sbjct: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Query: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT
Sbjct: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
Query: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
Query: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
Query: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
Query: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
Query: 541 EVSTDAAVLSVPAVTLVA 558
EVSTDAAVLSVPAVTLVA
Sbjct: 541 EVSTDAAVLSVPAVTLVA 558
>gi|154426253 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 1113 bits (2879), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
Query: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV
Sbjct: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Query: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT
Sbjct: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
Query: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
Query: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
Query: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
Query: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
Query: 541 EVSTDAAVLSVPAVTLVA 558
EVSTDAAVLSVPAVTLVA
Sbjct: 541 EVSTDAAVLSVPAVTLVA 558
>gi|154426310 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 1113 bits (2879), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
Query: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV
Sbjct: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Query: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT
Sbjct: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
Query: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
Query: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
Query: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
Query: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
Query: 541 EVSTDAAVLSVPAVTLVA 558
EVSTDAAVLSVPAVTLVA
Sbjct: 541 EVSTDAAVLSVPAVTLVA 558
>gi|154426312 SPATS2-like protein isoform b [Homo sapiens]
Length = 489
Score = 802 bits (2071), Expect = 0.0
Identities = 432/558 (77%), Positives = 450/558 (80%), Gaps = 69/558 (12%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 120
Query: 121 ANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWS 180
ANEKPALIPREKKISILEEPSKALRGVT N ++ + K +
Sbjct: 121 ANEKPALIPREKKISILEEPSKALRGVTGPN--------IEKSVKDL------------- 159
Query: 181 AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRV 240
Q C S + + ++ + D KK I+ + +L C + V
Sbjct: 160 --QRCTVSLTRYRVM----------IKEEVDSSVKK----IKAAFAELHNCIID---KEV 200
Query: 241 MIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLT 300
+ E+D K+K E+ L A K +E LKRLT
Sbjct: 201 SLMAEMD----KVKEEAMEI----------LTARQKKAEE---------------LKRLT 231
Query: 301 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 360
DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN
Sbjct: 232 DLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNN 291
Query: 361 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 420
YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ
Sbjct: 292 YSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQ 351
Query: 421 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 480
TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR
Sbjct: 352 TMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFR 411
Query: 481 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 540
PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI
Sbjct: 412 PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRI 471
Query: 541 EVSTDAAVLSVPAVTLVA 558
EVSTDAAVLSVPAVTLVA
Sbjct: 472 EVSTDAAVLSVPAVTLVA 489
>gi|148746220 spermatogenesis associated, serine-rich 2 [Homo
sapiens]
Length = 545
Score = 322 bits (826), Expect = 4e-88
Identities = 214/535 (40%), Positives = 305/535 (57%), Gaps = 35/535 (6%)
Query: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
+A+ N+KEKI AVR++VPNKSNNEI+LVLQ FD VDK VQAF++GSA +VLKEW
Sbjct: 23 LAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWT 82
Query: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGP----MNGCEKDSS 116
+TGKKKN K+K + + D + Q P + G +NG D+
Sbjct: 83 VTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTE 142
Query: 117 STDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDG 176
S DS +E + + + LE+P A+ + + Q D K + + +
Sbjct: 143 SVDSLSEGLETLSIDARE--LEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHN-- 198
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
++QP N +K ++ + ++ +E P +KK NIEKSVKDLQRCTVSL
Sbjct: 199 ----SQQPRNAAKSLSRPT-TETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLA 253
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
RYRV++KEE+D+S+KK+K AFAEL +C++D+EV+L+AEMDKVK EAMEIL +RQKKAE L
Sbjct: 254 RYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELL 313
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
K++T +A QM+E QL ELRA+IKHFVSERKYDE+LG+ ARF+CD+E LK I G+++H
Sbjct: 314 KKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSH 373
Query: 357 PKNNYSSRTPCSSLLPL-----LNAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMV 408
PKN+YS+R+ CSS+ + +A AA+S ++ +S + K P E AA +
Sbjct: 374 PKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IA 430
Query: 409 SSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNS 467
+S P + +P N++ G Q R Q N+ +N G S G + G S
Sbjct: 431 NSSGQPYQPLREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-S 486
Query: 468 RHEH--RRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADT 517
R++ + P N A + M+ P P S K P+R+ + T
Sbjct: 487 RYQSAPSQAPGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQT 540
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/274 (20%), Positives = 120/274 (43%), Gaps = 32/274 (11%)
Query: 94 GPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIPREKKISILEEPSKALRGVTE---- 149
G LQ Q +Q + D S+ +++ K + E++ S+L+ + LR + E
Sbjct: 1656 GQLQIQIKDLQ------MQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTER 1709
Query: 150 GNRLLQQKL---------------SLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKT 194
G RL +++L SL K + R Q C ++ KAK
Sbjct: 1710 GRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKK 1769
Query: 195 SPVKSNTPAAHLEIKPDELA--KKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKK 252
+ +++ + L+ K D +A ++ N+E+++ DLQ+ + +M + ++K
Sbjct: 1770 AAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRK---QIQK 1826
Query: 253 IKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEE-LKRLTDLASQMAEMQL 311
+++ EL ++ E+ AE + + +AEE K L+ + +QM ++QL
Sbjct: 1827 LESRVRELEG-ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQL 1885
Query: 312 AELRAEIKHFVSERKYDEELGKAARFSCDIEQLK 345
+ + V+E + ++ L K + ++ ++K
Sbjct: 1886 KVQNYKQQVEVAETQANQYLSKYKKQQHELNEVK 1919
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 45.1 bits (105), Expect = 2e-04
Identities = 66/302 (21%), Positives = 128/302 (42%), Gaps = 34/302 (11%)
Query: 72 RSKSKQHQGNKDAKDKVERPEAG--PLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIP 129
++ K + ++ +DK+ + E G L + ++ + KD T + ++ L
Sbjct: 350 KNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCREL-- 407
Query: 130 REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSK 189
KK+ E SK LR E +L ++ L+ + + L + E K
Sbjct: 408 -RKKLQEEEHHSKELR--LEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE------K 458
Query: 190 PKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 249
K T + + +K E ++ R E S+KD L + VM+ +E +
Sbjct: 459 EKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD---DLTKLKSFTVMLVDERKNM 515
Query: 250 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 309
++KIK +++V + + KV++ +++ +K EE K+L L S+M E
Sbjct: 516 MEKIKQE---------ERKVDGLNKNFKVEQG--KVMDVTEKLIEESKKLLKLKSEMEE- 563
Query: 310 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI----MLCGEITHPKNNYSSRT 365
++ L E + + K +EE K++ SC ++ LK ++ + EIT ++ S
Sbjct: 564 KVYNLTRERDELIGKLKSEEE--KSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 621
Query: 366 PC 367
C
Sbjct: 622 TC 623
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 43.5 bits (101), Expect = 5e-04
Identities = 56/253 (22%), Positives = 99/253 (39%), Gaps = 39/253 (15%)
Query: 57 KEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSS 116
+E + G+KKN KR K N+ +++VE P QPQ PQ Q C + S
Sbjct: 1425 EERDQKGEKKNQKRNEKK------NQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGS 1478
Query: 117 STDSANEKPALIPREKKISILEEPSKALR-GVTEGNRLLQQK--LSLDGNPKPIHG-TTE 172
+ ++KP KK + EE + EG ++ L + KP +
Sbjct: 1479 EQERVSKKP------KKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQ 1532
Query: 173 RSDGLQWS-------------AEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGP 219
S G W+ AE + K + +K + LE + A+K
Sbjct: 1533 LSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELE---KQKAEKELS 1589
Query: 220 NIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVK 279
IE+++ D R S + ++ +SS+ ++ L I+K + V
Sbjct: 1590 RIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARA-------VA 1642
Query: 280 EEAMEILTARQKK 292
E A++ ++ R+++
Sbjct: 1643 ERALKTISFREEQ 1655
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 43.5 bits (101), Expect = 5e-04
Identities = 67/289 (23%), Positives = 109/289 (37%), Gaps = 55/289 (19%)
Query: 265 IDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDL-ASQMAEMQLAELRAEIKHF-- 321
+D + S+ + D +K K EE+K+ D S + E + L++ ++
Sbjct: 551 VDSQASITQDSDSIK------------KPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPE 598
Query: 322 VSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATS 381
++K D EL K+ +++Q ++++ + P N T S T
Sbjct: 599 TPKKKSDPELSKS-----EMKQSESRLAE----SKPNENRLVETKSSENKLETKVETQTE 649
Query: 382 GKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNP-- 439
+ N SR +T K +E PK + S P+ NKQN ++ + P
Sbjct: 650 ELKQNESR--TTECKQNESTIVEPKQNENRLSDTKPND-----NKQNNGRSETTKSRPET 702
Query: 440 --QYHNNRLNGPA----------KSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGA 487
Q +R P K +G G P KG SR E +Q + G RP+
Sbjct: 703 PKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEG-RPETPKHR 761
Query: 488 KNQEASLGM----KTPEAPAH-----SEKPRRRQHAADTSEARPFRGSV 527
+ G K PE H S+ PR + A+ + RP SV
Sbjct: 762 HDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV 810
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 43.5 bits (101), Expect = 5e-04
Identities = 67/289 (23%), Positives = 109/289 (37%), Gaps = 55/289 (19%)
Query: 265 IDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDL-ASQMAEMQLAELRAEIKHF-- 321
+D + S+ + D +K K EE+K+ D S + E + L++ ++
Sbjct: 551 VDSQASITQDSDSIK------------KPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPE 598
Query: 322 VSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATS 381
++K D EL K+ +++Q ++++ + P N T S T
Sbjct: 599 TPKKKSDPELSKS-----EMKQSESRLAE----SKPNENRLVETKSSENKLETKVETQTE 649
Query: 382 GKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNP-- 439
+ N SR +T K +E PK + S P+ NKQN ++ + P
Sbjct: 650 ELKQNESR--TTECKQNESTIVEPKQNENRLSDTKPND-----NKQNNGRSETTKSRPET 702
Query: 440 --QYHNNRLNGPA----------KSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGA 487
Q +R P K +G G P KG SR E +Q + G RP+
Sbjct: 703 PKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEG-RPETPKHR 761
Query: 488 KNQEASLGM----KTPEAPAH-----SEKPRRRQHAADTSEARPFRGSV 527
+ G K PE H S+ PR + A+ + RP SV
Sbjct: 762 HDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV 810
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/159 (30%), Positives = 69/159 (43%), Gaps = 24/159 (15%)
Query: 24 KSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTG-KKKNNKRKRSKSKQHQGN- 81
K NN IV F D F G Q L ++ G +++ K+KRSK+K+
Sbjct: 601 KKNNHIVAEDPSKGFGKDD----FPGGVDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEP 656
Query: 82 KDAKDKVERPEAGPLQPQPPQIQNGP-----MNGCEKDSSSTDSANEKPALIPREKKISI 136
K+ K+K E E P P+ P+I P K SS S+N+KP + + S
Sbjct: 657 KEPKEKKEPKE--PKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKP-----DSEASA 709
Query: 137 LEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSD 175
L++ K +G TEG+ + LD P P E D
Sbjct: 710 LKK--KVNKGKTEGS----ENSDLDKTPPPSPPPEEDED 742
Score = 31.2 bits (69), Expect = 2.6
Identities = 40/181 (22%), Positives = 74/181 (40%), Gaps = 22/181 (12%)
Query: 356 HPKNNYSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTH-NKPSEGKAANPKMVSSLPST 414
HP ++ S P P H + N +K H + PSE P V +
Sbjct: 520 HPGLHHQSSPPHPHHQPWAQLHPSPQ----NTPQKVPVHQHSPSEPFLEKP--VPDMTQV 573
Query: 415 ADPSHQTMPANKQNGSSNQR-RRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGN------- 466
+ P+ Q + ++ S Q+ ++ + NN + S+G G + P G N
Sbjct: 574 SGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNS 633
Query: 467 ---SRHEHRRQPHNGFR--PKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEAR 521
S+ E +++ + + PK K ++ KTP+AP ++P+ ++ A T+ +
Sbjct: 634 LDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKK--AKTATPK 691
Query: 522 P 522
P
Sbjct: 692 P 692
Score = 30.0 bits (66), Expect = 5.8
Identities = 35/137 (25%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 97 QPQPPQIQ-NGPMNGCEKDSSSTDSANEKPALIPREKKIS--ILEEPSKALRGVTEGNRL 153
+P P Q +GP K S ++P ++KK + + E+PSK +
Sbjct: 565 KPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGV 624
Query: 154 LQQKL---SLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTP-AAHLEIK 209
Q+L SLDG+ + ++ + + P P +PK K P + TP A + +
Sbjct: 625 DNQELNRNSLDGSQEE-----KKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKE 679
Query: 210 PDELAKKRGPNIEKSVK 226
P E K KS K
Sbjct: 680 PKEKKAKTATPKPKSSK 696
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 40.0 bits (92), Expect = 0.006
Identities = 45/202 (22%), Positives = 77/202 (38%), Gaps = 37/202 (18%)
Query: 167 IHGTTERSDGLQWSAEQPCNPSKPKAKTS-PVKSNTPAAHLEIKPDELAKKRGPNIEKSV 225
I G TE D L S C+ S P AK++ P S ++H EI N + +
Sbjct: 1793 IPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN----------NYLQQI 1842
Query: 226 KDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEI 285
L+ R+ EE K+ N ++ + + E+ ++EE ++
Sbjct: 1843 DQLKE--------RIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM 1894
Query: 286 LTARQKKAEELKRLTDLASQMAE----------MQLAELRAEIKHF--------VSERKY 327
Q+ EEL R+T L E QLAEL I ++ +
Sbjct: 1895 NLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELL 1954
Query: 328 DEELGKAARFSCDIEQLKAQIM 349
+ E+ + ++E+ K Q++
Sbjct: 1955 ESEMKNLKKCVSELEEEKQQLV 1976
Score = 30.0 bits (66), Expect = 5.8
Identities = 47/242 (19%), Positives = 101/242 (41%), Gaps = 44/242 (18%)
Query: 133 KISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPI----HGTTERSDGLQWSAEQPCNPS 188
++++L+E L +TE +R L + SL + + + G TE + L E
Sbjct: 1540 RLALLQEERDKL--ITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES----- 1592
Query: 189 KPKAKTSPVKSNTP--AAHLEIKPD-ELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEE 245
K+S + +T H E++ + E+ + N+ + +Q ++ + K+E
Sbjct: 1593 ---LKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE----KQE 1645
Query: 246 VDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTD---- 301
+ ++ +A E + + E EM+++KE+ + ++Q+K EL+ D
Sbjct: 1646 LYGKLRSTEANKKETEKQLQEAE----QEMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701
Query: 302 ---------------LASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKA 346
L S A M+ R ++++ +K+ + + S +++ LK
Sbjct: 1702 EVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKH 1761
Query: 347 QI 348
QI
Sbjct: 1762 QI 1763
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 38.5 bits (88), Expect = 0.016
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 31/219 (14%)
Query: 112 EKDSSSTDSANEKPALIPREKKISILEEPSKALRG--VTEGNRLLQQKLSLDGNPKPIHG 169
E DS S D + + +P EK E+ AL+ V +L + K + + IH
Sbjct: 775 ENDSLSKDVSRLETVFVPPEKH----EKEIIALKSNIVELKKQLSELKKKCGEDQEKIHA 830
Query: 170 TTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKP---DELAKKRGP--NIEKS 224
T + L+ P K H E+K D LAK +++K
Sbjct: 831 LTSENTNLKKMMSNQYVPVK--------------THEEVKMTLNDTLAKTNRELLDVKKK 876
Query: 225 VKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAEL--HNCIIDKEVSLMAEMDKVKEEA 282
+D+ + V + ++K ++++ +IKA + L H K SL M KV++
Sbjct: 877 FEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEA---KMSSLSQSMRKVQDSN 933
Query: 283 MEILTARQKKAEELKRL-TDLASQMAEMQLAELRAEIKH 320
EIL +K EE+ L ++ +Q E+ + ++K+
Sbjct: 934 AEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKY 972
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 38.5 bits (88), Expect = 0.016
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 31/219 (14%)
Query: 112 EKDSSSTDSANEKPALIPREKKISILEEPSKALRG--VTEGNRLLQQKLSLDGNPKPIHG 169
E DS S D + + +P EK E+ AL+ V +L + K + + IH
Sbjct: 788 ENDSLSKDVSRLETVFVPPEKH----EKEIIALKSNIVELKKQLSELKKKCGEDQEKIHA 843
Query: 170 TTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKP---DELAKKRGP--NIEKS 224
T + L+ P K H E+K D LAK +++K
Sbjct: 844 LTSENTNLKKMMSNQYVPVK--------------THEEVKMTLNDTLAKTNRELLDVKKK 889
Query: 225 VKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAEL--HNCIIDKEVSLMAEMDKVKEEA 282
+D+ + V + ++K ++++ +IKA + L H K SL M KV++
Sbjct: 890 FEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEA---KMSSLSQSMRKVQDSN 946
Query: 283 MEILTARQKKAEELKRL-TDLASQMAEMQLAELRAEIKH 320
EIL +K EE+ L ++ +Q E+ + ++K+
Sbjct: 947 AEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKY 985
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 38.5 bits (88), Expect = 0.016
Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 11/157 (7%)
Query: 212 ELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNC--IIDKEV 269
E+ KKR +K +DL+ T+ ++++ SV ++ L ++KE
Sbjct: 1164 EMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEK 1223
Query: 270 S-LMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSER-KY 327
S E+D V +I+ A+ + + L D A++ ++L E + + F ++R K
Sbjct: 1224 SEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY-RVKLEEAQRSLNDFTTQRAKL 1282
Query: 328 DEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSR 364
E G+ AR QL+ + L ++T K +Y+ +
Sbjct: 1283 QTENGELAR------QLEEKEALISQLTRGKLSYTQQ 1313
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 38.1 bits (87), Expect = 0.021
Identities = 55/234 (23%), Positives = 103/234 (44%), Gaps = 31/234 (13%)
Query: 212 ELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIID---KE 268
EL +K N E+ +K+ ++ + +++ +E KIK E + I+D K
Sbjct: 1229 ELVQKLS-NYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTL--EKNQEILDDTAKN 1285
Query: 269 VSLMAEMDKVKE-EAMEILTARQKKAEELKRLTDL-ASQMAEMQLAELRAEIK------- 319
+ +M E ++ + + ++++ +K E+LK + + AS+ +E+Q+A A++
Sbjct: 1286 LRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEEKVKSE 1345
Query: 320 -HFVSE-----RKYDEELGKA--------ARFSCDIEQL-KAQIMLCGEITHPKNNYSSR 364
H V E +K E+L + A S I+ K+Q L +TH +N ++
Sbjct: 1346 CHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNINAL 1405
Query: 365 TPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPS 418
T C + L LL + + G Q+ S G N KM + + D S
Sbjct: 1406 TNCITQLNLLECESESEG-QNKGGNDSDELANGEVGGDRNEKMKNQIKQMMDVS 1458
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 37.7 bits (86), Expect = 0.028
Identities = 41/198 (20%), Positives = 78/198 (39%), Gaps = 18/198 (9%)
Query: 185 CNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRG-PNIEKSVKDLQRCTVSLTRYRVMIK 243
C P K T K + +L + P + R +++ K++ R L+R +K
Sbjct: 12346 CTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVK 12405
Query: 244 EEVDSS----------VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKA 293
D + + K ++ C++D E E+ + M LT +++A
Sbjct: 12406 WFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGM--LTVLEEEA 12463
Query: 294 EELKRLTDLASQMAEMQLAELRAEIKHFVSE---RKYDEELGKAARFSCDIEQLKAQIML 350
K L ++ +++E +L E+ +E K DEE+ + R+ E K +++
Sbjct: 12464 VFTKNLANI--EVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVI 12521
Query: 351 CGEITHPKNNYSSRTPCS 368
NY+ R P S
Sbjct: 12522 QNAHLEDAGNYNCRLPSS 12539
Score = 32.7 bits (73), Expect = 0.90
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 20/131 (15%)
Query: 214 AKKRGPNIEKSV-KDLQRCTV-SLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSL 271
+++R + +SV +L R +++ ++ + E SSV+++K+ E + E S
Sbjct: 32473 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 32532
Query: 272 MAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEEL 331
AEM K A+E +K EE + + +A L + R S Y+
Sbjct: 32533 SAEM---KSAALE-----EKSLEEKSTTRKIKTTLAARILTKPR-------SMTVYE--- 32574
Query: 332 GKAARFSCDIE 342
G++ARFSCD +
Sbjct: 32575 GESARFSCDTD 32585
Score = 29.3 bits (64), Expect = 10.0
Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Query: 268 EVSLMAEMDKVKEEAMEILTARQKKAEELK-RLTDLASQMAEMQLAELRAEIKHFVSERK 326
E L +++ E M+ ++K E L+ L LA E+Q A + F + R+
Sbjct: 3437 ESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP-NVRFQWFKAGRE 3495
Query: 327 Y---DEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAAT 380
D+ +++++ +E L+ Q++ CGE T +N C++ L + A+ T
Sbjct: 3496 IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPT 3552
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 37.7 bits (86), Expect = 0.028
Identities = 41/198 (20%), Positives = 78/198 (39%), Gaps = 18/198 (9%)
Query: 185 CNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRG-PNIEKSVKDLQRCTVSLTRYRVMIK 243
C P K T K + +L + P + R +++ K++ R L+R +K
Sbjct: 6041 CTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVK 6100
Query: 244 EEVDSS----------VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKA 293
D + + K ++ C++D E E+ + M LT +++A
Sbjct: 6101 WFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGM--LTVLEEEA 6158
Query: 294 EELKRLTDLASQMAEMQLAELRAEIKHFVSE---RKYDEELGKAARFSCDIEQLKAQIML 350
K L ++ +++E +L E+ +E K DEE+ + R+ E K +++
Sbjct: 6159 VFTKNLANI--EVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVI 6216
Query: 351 CGEITHPKNNYSSRTPCS 368
NY+ R P S
Sbjct: 6217 QNAHLEDAGNYNCRLPSS 6234
Score = 32.7 bits (73), Expect = 0.90
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 20/131 (15%)
Query: 214 AKKRGPNIEKSV-KDLQRCTV-SLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSL 271
+++R + +SV +L R +++ ++ + E SSV+++K+ E + E S
Sbjct: 26168 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26227
Query: 272 MAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEEL 331
AEM K A+E +K EE + + +A L + R S Y+
Sbjct: 26228 SAEM---KSAALE-----EKSLEEKSTTRKIKTTLAARILTKPR-------SMTVYE--- 26269
Query: 332 GKAARFSCDIE 342
G++ARFSCD +
Sbjct: 26270 GESARFSCDTD 26280
Score = 32.3 bits (72), Expect = 1.2
Identities = 64/323 (19%), Positives = 125/323 (38%), Gaps = 42/323 (13%)
Query: 82 KDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSS-TDSANEKPALIPREKKISILEEP 140
+DA + E L + P+IQ G +++ S + S +P P + ++
Sbjct: 4303 RDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTE 4362
Query: 141 SKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSN 200
+ V + L G + ++ + L+ PS+ K ++S
Sbjct: 4363 EVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLK--------PSEEKEESSSESGT 4414
Query: 201 TPAAHLEIKPDE--LAKKRGPNIEKSVKD-------LQRCTVSLTRYRVM---IKEEVDS 248
A ++I+ E L K+ GP I + D + T S+T + + + ++
Sbjct: 4415 EEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFENKLVP 4474
Query: 249 SVKKIKAAFAE-LHNCIIDK--------EVSLMAEMDKVKEEAMEILTARQKKAEELKRL 299
S +K K + + +IDK E A D K LT ++ A +KR
Sbjct: 4475 SDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRK 4534
Query: 300 TDLASQMAEMQLAELRAEIKHFVSER-----------KYDEELGKAARFSCDIEQLKAQI 348
+ ++A LA+ EI+ + R + D+ +++++ +E L+ Q+
Sbjct: 4535 IE-PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQV 4593
Query: 349 MLCGEITHPKNNYSSRTPCSSLL 371
+ CGE T +N C++ L
Sbjct: 4594 VDCGEYTCKASNEYGSVSCTATL 4616
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 37.7 bits (86), Expect = 0.028
Identities = 41/198 (20%), Positives = 78/198 (39%), Gaps = 18/198 (9%)
Query: 185 CNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRG-PNIEKSVKDLQRCTVSLTRYRVMIK 243
C P K T K + +L + P + R +++ K++ R L+R +K
Sbjct: 5974 CTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVK 6033
Query: 244 EEVDSS----------VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKA 293
D + + K ++ C++D E E+ + M LT +++A
Sbjct: 6034 WFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGM--LTVLEEEA 6091
Query: 294 EELKRLTDLASQMAEMQLAELRAEIKHFVSE---RKYDEELGKAARFSCDIEQLKAQIML 350
K L ++ +++E +L E+ +E K DEE+ + R+ E K +++
Sbjct: 6092 VFTKNLANI--EVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVI 6149
Query: 351 CGEITHPKNNYSSRTPCS 368
NY+ R P S
Sbjct: 6150 QNAHLEDAGNYNCRLPSS 6167
Score = 32.7 bits (73), Expect = 0.90
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 20/131 (15%)
Query: 214 AKKRGPNIEKSV-KDLQRCTV-SLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSL 271
+++R + +SV +L R +++ ++ + E SSV+++K+ E + E S
Sbjct: 26101 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26160
Query: 272 MAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEEL 331
AEM K A+E +K EE + + +A L + R S Y+
Sbjct: 26161 SAEM---KSAALE-----EKSLEEKSTTRKIKTTLAARILTKPR-------SMTVYE--- 26202
Query: 332 GKAARFSCDIE 342
G++ARFSCD +
Sbjct: 26203 GESARFSCDTD 26213
Score = 32.3 bits (72), Expect = 1.2
Identities = 64/323 (19%), Positives = 125/323 (38%), Gaps = 42/323 (13%)
Query: 82 KDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSS-TDSANEKPALIPREKKISILEEP 140
+DA + E L + P+IQ G +++ S + S +P P + ++
Sbjct: 4236 RDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTE 4295
Query: 141 SKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSN 200
+ V + L G + ++ + L+ PS+ K ++S
Sbjct: 4296 EVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLK--------PSEEKEESSSESGT 4347
Query: 201 TPAAHLEIKPDE--LAKKRGPNIEKSVKD-------LQRCTVSLTRYRVM---IKEEVDS 248
A ++I+ E L K+ GP I + D + T S+T + + + ++
Sbjct: 4348 EEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFENKLVP 4407
Query: 249 SVKKIKAAFAE-LHNCIIDK--------EVSLMAEMDKVKEEAMEILTARQKKAEELKRL 299
S +K K + + +IDK E A D K LT ++ A +KR
Sbjct: 4408 SDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRK 4467
Query: 300 TDLASQMAEMQLAELRAEIKHFVSER-----------KYDEELGKAARFSCDIEQLKAQI 348
+ ++A LA+ EI+ + R + D+ +++++ +E L+ Q+
Sbjct: 4468 IE-PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQV 4526
Query: 349 MLCGEITHPKNNYSSRTPCSSLL 371
+ CGE T +N C++ L
Sbjct: 4527 VDCGEYTCKASNEYGSVSCTATL 4549
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 37.7 bits (86), Expect = 0.028
Identities = 41/198 (20%), Positives = 78/198 (39%), Gaps = 18/198 (9%)
Query: 185 CNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRG-PNIEKSVKDLQRCTVSLTRYRVMIK 243
C P K T K + +L + P + R +++ K++ R L+R +K
Sbjct: 5849 CTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVK 5908
Query: 244 EEVDSS----------VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKA 293
D + + K ++ C++D E E+ + M LT +++A
Sbjct: 5909 WFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGM--LTVLEEEA 5966
Query: 294 EELKRLTDLASQMAEMQLAELRAEIKHFVSE---RKYDEELGKAARFSCDIEQLKAQIML 350
K L ++ +++E +L E+ +E K DEE+ + R+ E K +++
Sbjct: 5967 VFTKNLANI--EVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVI 6024
Query: 351 CGEITHPKNNYSSRTPCS 368
NY+ R P S
Sbjct: 6025 QNAHLEDAGNYNCRLPSS 6042
Score = 32.7 bits (73), Expect = 0.90
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 20/131 (15%)
Query: 214 AKKRGPNIEKSV-KDLQRCTV-SLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSL 271
+++R + +SV +L R +++ ++ + E SSV+++K+ E + E S
Sbjct: 25976 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26035
Query: 272 MAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEEL 331
AEM K A+E +K EE + + +A L + R S Y+
Sbjct: 26036 SAEM---KSAALE-----EKSLEEKSTTRKIKTTLAARILTKPR-------SMTVYE--- 26077
Query: 332 GKAARFSCDIE 342
G++ARFSCD +
Sbjct: 26078 GESARFSCDTD 26088
Score = 32.3 bits (72), Expect = 1.2
Identities = 64/323 (19%), Positives = 125/323 (38%), Gaps = 42/323 (13%)
Query: 82 KDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSS-TDSANEKPALIPREKKISILEEP 140
+DA + E L + P+IQ G +++ S + S +P P + ++
Sbjct: 4111 RDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTE 4170
Query: 141 SKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSN 200
+ V + L G + ++ + L+ PS+ K ++S
Sbjct: 4171 EVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLK--------PSEEKEESSSESGT 4222
Query: 201 TPAAHLEIKPDE--LAKKRGPNIEKSVKD-------LQRCTVSLTRYRVM---IKEEVDS 248
A ++I+ E L K+ GP I + D + T S+T + + + ++
Sbjct: 4223 EEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFENKLVP 4282
Query: 249 SVKKIKAAFAE-LHNCIIDK--------EVSLMAEMDKVKEEAMEILTARQKKAEELKRL 299
S +K K + + +IDK E A D K LT ++ A +KR
Sbjct: 4283 SDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRK 4342
Query: 300 TDLASQMAEMQLAELRAEIKHFVSER-----------KYDEELGKAARFSCDIEQLKAQI 348
+ ++A LA+ EI+ + R + D+ +++++ +E L+ Q+
Sbjct: 4343 IE-PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQV 4401
Query: 349 MLCGEITHPKNNYSSRTPCSSLL 371
+ CGE T +N C++ L
Sbjct: 4402 VDCGEYTCKASNEYGSVSCTATL 4424
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1534 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1586
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1587 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1645
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1757
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1758 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1816
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1817 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1849
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 1995 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2054
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2055 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2114
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2115 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2234 RVQMEELSKLKARI 2247
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2266 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2323
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2324 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2379
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2380 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2438
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2439 QQSDHDA 2445
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1538 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1590
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1591 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1649
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1709
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1761
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1762 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1820
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1821 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1853
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 1999 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2058
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2059 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2118
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2119 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2177
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2178 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2237
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2238 RVQMEELSKLKARI 2251
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2270 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2327
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2328 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2383
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2384 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2442
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2443 QQSDHDA 2449
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1534 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1586
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1587 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1645
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1757
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1758 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1816
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1817 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1849
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 1995 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2054
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2055 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2114
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2115 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2234 RVQMEELSKLKARI 2247
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2266 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2323
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2324 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2379
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2380 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2438
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2439 QQSDHDA 2445
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1502 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1554
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1555 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1613
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1673
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1725
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1726 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1784
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1785 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1817
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 1963 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2022
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2023 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2082
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2083 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2141
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2142 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2201
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2202 RVQMEELSKLKARI 2215
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2234 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2291
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2292 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2347
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2348 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2406
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2407 QQSDHDA 2413
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1671 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1723
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1724 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1782
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1783 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1842
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1894
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1895 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1953
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1954 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1986
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 2132 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2191
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2192 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2251
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2252 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2310
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2311 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2370
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2371 RVQMEELSKLKARI 2384
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2403 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2460
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2461 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2516
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2517 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2575
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2576 QQSDHDA 2582
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1512 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1564
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1565 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1623
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1624 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1683
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1735
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1736 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1794
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1795 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1827
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 1973 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2032
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2033 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2092
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2093 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2151
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2152 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2211
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2212 RVQMEELSKLKARI 2225
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2244 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2301
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2302 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2357
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2358 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2416
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2417 QQSDHDA 2423
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1520 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1572
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1573 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1631
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1632 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1691
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1743
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1744 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1802
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1803 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1835
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 1981 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2040
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2041 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2100
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2101 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2159
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2160 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2219
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2220 RVQMEELSKLKARI 2233
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2252 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2309
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2310 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2365
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2366 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2424
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2425 QQSDHDA 2431
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 37.7 bits (86), Expect = 0.028
Identities = 73/333 (21%), Positives = 135/333 (40%), Gaps = 43/333 (12%)
Query: 52 AIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGC 111
A+Q L+E + ++ + ++++ ++ + + A + +R LQ +
Sbjct: 1561 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF-------A 1613
Query: 112 EKDSSSTDSANEKPALIP--REKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPK---- 165
EK + S E+ + RE+ ++ ++A R E R L+ + L N
Sbjct: 1614 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLR 1672
Query: 166 -PIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPN---- 220
++ Q AE+ ++ +A+ E+ EL K+R
Sbjct: 1673 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1732
Query: 221 -----IEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEM 275
E+ + L+ T + R +++EE+ ++ AA K L AE+
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA--------TQKRQELEAEL 1784
Query: 276 DKVKEEAMEILTARQKKAEELKRLTDLASQM---AE----MQLAELRAEIKHFVSERKYD 328
KV+ E ME+L A + +AEE R T S+ AE +LAE A ++ E K
Sbjct: 1785 AKVRAE-MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1843
Query: 329 EELGK--AARFSCDIEQLKAQ-IMLCGEITHPK 358
+L + AAR + E++ A+ + GE T K
Sbjct: 1844 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLK 1876
Score = 31.6 bits (70), Expect = 2.0
Identities = 45/254 (17%), Positives = 105/254 (41%), Gaps = 21/254 (8%)
Query: 115 SSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERS 174
++ ++A ++ A + +++ E ++ LR E Q +L+ + K + +
Sbjct: 2022 AAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2081
Query: 175 DGLQWSAEQPCNPSKPKAKT--SPVKSNTPAAHLEIKPDELAK----KRGPNIEKSVKDL 228
EQ + + ++ ++ AA + E A+ + + V++
Sbjct: 2082 AFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEA 2141
Query: 229 QRCTVSLTRYRVMIKEEVDSSVKKIK-------AAFAELHNCIIDKEVSLMAEMDKVKEE 281
+R S + + + ++ +K++ A A+ + ++ + AEM+K K+
Sbjct: 2142 ERLKQSAEE-QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2200
Query: 282 AMEILTARQKKAEELKRL------TDLASQMAEMQLAELRAEIKHFVSER-KYDEELGKA 334
A + L + + +EL L TD + + +L L+AE +R + +EEL
Sbjct: 2201 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2260
Query: 335 ARFSCDIEQLKAQI 348
++ +LKA+I
Sbjct: 2261 RVQMEELSKLKARI 2274
Score = 31.2 bits (69), Expect = 2.6
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 7/187 (3%)
Query: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
LQ AE+ ++ A+ S V + A ++ ++LA++R EK +K+ + T
Sbjct: 2293 LQEEAEKMKQVAEEAARLS-VAAQEAARLRQLAEEDLAQQRAL-AEKMLKEKMQAVQEAT 2350
Query: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
R +K E + ++ + A + DKE ++ + + RQ++ E
Sbjct: 2351 R----LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2406
Query: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
L ++AEM A+ RAE + RK EE+G+ + Q K ++ EI
Sbjct: 2407 AEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2465
Query: 357 PKNNYSS 363
++++ +
Sbjct: 2466 QQSDHDA 2472
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 37.7 bits (86), Expect = 0.028
Identities = 51/251 (20%), Positives = 96/251 (38%), Gaps = 30/251 (11%)
Query: 101 PQIQNGPMNGCEKDSSSTDSANE-----KPALIPREKKISILEEPSKALRGVTEGNRLLQ 155
P++ +GP K+ S A K ++ + +++ K+L +G +
Sbjct: 208 PELTSGPRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATPQGKNMTP 267
Query: 156 QKLSLDGNPKP---IHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIK--- 209
+ L+ P+ + ++ S S E P P K + TSP ++TP + K
Sbjct: 268 ESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVK 327
Query: 210 -------------PDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVK-KIKA 255
+ L K+ E+ K+ + + K+E + +K K +
Sbjct: 328 GSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERR 387
Query: 256 AFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELR 315
E ++ L E K ++EA+E ++K EE KRL + E ++ +
Sbjct: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE-----EEKRIKAEK 442
Query: 316 AEIKHFVSERK 326
AEI F + K
Sbjct: 443 AEITRFFQKPK 453
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 37.4 bits (85), Expect = 0.037
Identities = 28/104 (26%), Positives = 53/104 (50%), Gaps = 14/104 (13%)
Query: 245 EVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLAS 304
++ + +++A AEL + KE L A + +V+EEA + K LK++ +L S
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ-------KNMALKKIRELES 1111
Query: 305 QMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQI 348
Q++E+Q +L +E K +LG+ ++E LK ++
Sbjct: 1112 QISELQ-EDLESERASRNKAEKQKRDLGE------ELEALKTEL 1148
Score = 34.7 bits (78), Expect = 0.24
Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 22/182 (12%)
Query: 157 KLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKK 216
KL L+ N + + ER LQ EQ + K K V+ E K +A
Sbjct: 1555 KLRLEVNLQAMKAQFERD--LQGRDEQ--SEEKKKQLVRQVREMEAELEDERKQRSMAVA 1610
Query: 217 RGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMD 276
+E +KDL+ S + R D ++K+++ A++ +C M E+D
Sbjct: 1611 ARKKLEMDLKDLEAHIDSANKNR-------DEAIKQLRKLQAQMKDC--------MRELD 1655
Query: 277 KVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAAR 336
+ EIL A+ K+ E K+L + ++M ++Q AE ++++ DE + A
Sbjct: 1656 DTRASREEIL-AQAKENE--KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1712
Query: 337 FS 338
S
Sbjct: 1713 SS 1714
Score = 32.3 bits (72), Expect = 1.2
Identities = 65/313 (20%), Positives = 115/313 (36%), Gaps = 61/313 (19%)
Query: 23 NKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGNK 82
NK+ +E + L++ + ++ D A +E + K+N K+ +S + +
Sbjct: 1630 NKNRDEAIKQLRKLQAQMKDCMRELDDTRAS---REEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 83 DAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANE--KPALIPREKK-----IS 135
+ ER + Q E+D + + AN K AL EK+ I+
Sbjct: 1687 EELAAAERAKRQAQQ--------------ERDELADEIANSSGKGALALEEKRRLEARIA 1732
Query: 136 ILEEPSKALRGVTE--GNRLLQQKLSLDG--------------NPKPIHGTTERSDGLQW 179
LEE + +G TE +RL + L +D N ++ L+
Sbjct: 1733 QLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV 1792
Query: 180 SAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGP------NIEKSVKDLQRCTV 233
++ K K K S A LE + D K+R EK +KD+
Sbjct: 1793 KLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVD 1852
Query: 234 SLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKA 293
R K++ D + ++K L ++++ +EEA +R+K
Sbjct: 1853 DERRNAEQYKDQADKASTRLK---------------QLKRQLEEAEEEAQRANASRRKLQ 1897
Query: 294 EELKRLTDLASQM 306
EL+ T+ A M
Sbjct: 1898 RELEDATETADAM 1910
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,305,089
Number of Sequences: 37866
Number of extensions: 1126983
Number of successful extensions: 5928
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 374
Number of HSP's that attempted gapping in prelim test: 5407
Number of HSP's gapped (non-prelim): 965
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.