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Search of human proteins with 154240671
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
(1585 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens] 3115 0.0
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens] 662 0.0
gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens] 656 0.0
gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens] 644 0.0
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens] 603 e-172
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5... 483 e-136
gi|148727311 hypothetical protein LOC389690 [Homo sapiens] 196 1e-49
gi|223278410 hypothetical protein LOC374977 [Homo sapiens] 150 9e-36
gi|187761375 maestro isoform a [Homo sapiens] 149 2e-35
gi|187761381 maestro isoform d [Homo sapiens] 142 2e-33
gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi... 142 3e-33
gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens] 107 9e-23
gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens] 107 9e-23
gi|187761377 maestro isoform b [Homo sapiens] 86 3e-16
gi|154937380 hypothetical protein LOC642475 [Homo sapiens] 86 3e-16
gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens] 83 2e-15
gi|187761379 maestro isoform c [Homo sapiens] 79 3e-14
gi|117956387 hypothetical protein LOC80133 [Homo sapiens] 60 1e-08
gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens] 57 1e-07
gi|7706457 A-kinase anchor protein 11 [Homo sapiens] 36 0.26
gi|71061468 centromere protein E [Homo sapiens] 35 0.58
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 33 2.9
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 32 4.9
gi|61743978 stabilin 1 precursor [Homo sapiens] 32 4.9
gi|148612844 ATP-binding cassette, sub-family B, member 5 [Homo ... 31 8.3
gi|4759082 serum deprivation response protein [Homo sapiens] 31 8.3
gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6 [... 31 8.3
gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5 [... 31 8.3
gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4 [... 31 8.3
gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3 [... 31 8.3
>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
Length = 1585
Score = 3115 bits (8077), Expect = 0.0
Identities = 1585/1585 (100%), Positives = 1585/1585 (100%)
Query: 1 MTLSTEESIEMFGDINLTLGMLNKEDIVNKEDIYSHLTSVIQNTDILDDAIVQRLIYYAS 60
MTLSTEESIEMFGDINLTLGMLNKEDIVNKEDIYSHLTSVIQNTDILDDAIVQRLIYYAS
Sbjct: 1 MTLSTEESIEMFGDINLTLGMLNKEDIVNKEDIYSHLTSVIQNTDILDDAIVQRLIYYAS 60
Query: 61 KDMRDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPDEFVVLALAELATSY 120
KDMRDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPDEFVVLALAELATSY
Sbjct: 61 KDMRDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPDEFVVLALAELATSY 120
Query: 121 VSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSKAIYKYVNHWRDFPYPRLDAN 180
VSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSKAIYKYVNHWRDFPYPRLDAN
Sbjct: 121 VSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSKAIYKYVNHWRDFPYPRLDAN 180
Query: 181 RLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQ 240
RLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQ
Sbjct: 181 RLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQ 240
Query: 241 YKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSIFINLLQQICRAPEPPVKENEMKAS 300
YKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSIFINLLQQICRAPEPPVKENEMKAS
Sbjct: 241 YKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSIFINLLQQICRAPEPPVKENEMKAS 300
Query: 301 SCFLILAHSNPGELMEFFDEQVRSNNEAIRVGILTLLRLAVNADEPRLRDHIISIERTVK 360
SCFLILAHSNPGELMEFFDEQVRSNNEAIRVGILTLLRLAVNADEPRLRDHIISIERTVK
Sbjct: 301 SCFLILAHSNPGELMEFFDEQVRSNNEAIRVGILTLLRLAVNADEPRLRDHIISIERTVK 360
Query: 361 IVMGDLSTKVRNSVLLLIQTMCEKSYIEAREGWPLIDYVFSQFATLNRNLEKPVKTNFHE 420
IVMGDLSTKVRNSVLLLIQTMCEKSYIEAREGWPLIDYVFSQFATLNRNLEKPVKTNFHE
Sbjct: 361 IVMGDLSTKVRNSVLLLIQTMCEKSYIEAREGWPLIDYVFSQFATLNRNLEKPVKTNFHE 420
Query: 421 NEKEEESVRETSLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMA 480
NEKEEESVRETSLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMA
Sbjct: 421 NEKEEESVRETSLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMA 480
Query: 481 EEKKQHSAKESTALVVSTGAVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEI 540
EEKKQHSAKESTALVVSTGAVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEI
Sbjct: 481 EEKKQHSAKESTALVVSTGAVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEI 540
Query: 541 IHPKLVDLWKTRLPELLQPLEGKNISTVLWETMLLQLLKESLWKISDVAWTIQLTQDFKQ 600
IHPKLVDLWKTRLPELLQPLEGKNISTVLWETMLLQLLKESLWKISDVAWTIQLTQDFKQ
Sbjct: 541 IHPKLVDLWKTRLPELLQPLEGKNISTVLWETMLLQLLKESLWKISDVAWTIQLTQDFKQ 600
Query: 601 QMGSYSNNSTEKKFLWKALGTTLACCQDSDFVNSQIKEFLTAPNQLGDQRQGITSILGYC 660
QMGSYSNNSTEKKFLWKALGTTLACCQDSDFVNSQIKEFLTAPNQLGDQRQGITSILGYC
Sbjct: 601 QMGSYSNNSTEKKFLWKALGTTLACCQDSDFVNSQIKEFLTAPNQLGDQRQGITSILGYC 660
Query: 661 AENHLDIVLKVLKTFQNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSR 720
AENHLDIVLKVLKTFQNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSR
Sbjct: 661 AENHLDIVLKVLKTFQNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSR 720
Query: 721 LNQDIISQVLSLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAEDQGFQFSYKE 780
LNQDIISQVLSLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAEDQGFQFSYKE
Sbjct: 721 LNQDIISQVLSLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAEDQGFQFSYKE 780
Query: 781 MLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLP 840
MLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLP
Sbjct: 781 MLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLP 840
Query: 841 PLENLKSEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQ 900
PLENLKSEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQ
Sbjct: 841 PLENLKSEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQ 900
Query: 901 KEWERERAFQITAKVLTNDIEAPENFKIGSLLGLLAPHSCDTLPTIRQAAASSTIGLFYI 960
KEWERERAFQITAKVLTNDIEAPENFKIGSLLGLLAPHSCDTLPTIRQAAASSTIGLFYI
Sbjct: 901 KEWERERAFQITAKVLTNDIEAPENFKIGSLLGLLAPHSCDTLPTIRQAAASSTIGLFYI 960
Query: 961 KGIHLEVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLN 1020
KGIHLEVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLN
Sbjct: 961 KGIHLEVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLN 1020
Query: 1021 PTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASF 1080
PTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASF
Sbjct: 1021 PTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASF 1080
Query: 1081 HMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDIARVEAIS 1140
HMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDIARVEAIS
Sbjct: 1081 HMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDIARVEAIS 1140
Query: 1141 VACAMYEVISMGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPD 1200
VACAMYEVISMGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPD
Sbjct: 1141 VACAMYEVISMGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPD 1200
Query: 1201 PCRLSTATLKCLQAQAMREGLAKESDEGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVI 1260
PCRLSTATLKCLQAQAMREGLAKESDEGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVI
Sbjct: 1201 PCRLSTATLKCLQAQAMREGLAKESDEGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVI 1260
Query: 1261 LDIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLR 1320
LDIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLR
Sbjct: 1261 LDIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLR 1320
Query: 1321 QMAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRD 1380
QMAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRD
Sbjct: 1321 QMAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRD 1380
Query: 1381 VSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLH 1440
VSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLH
Sbjct: 1381 VSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLH 1440
Query: 1441 LWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQE 1500
LWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQE
Sbjct: 1441 LWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQE 1500
Query: 1501 ILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPC 1560
ILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPC
Sbjct: 1501 ILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPC 1560
Query: 1561 ISVQRAAEAALQTLLRRCKETSIPL 1585
ISVQRAAEAALQTLLRRCKETSIPL
Sbjct: 1561 ISVQRAAEAALQTLLRRCKETSIPL 1585
>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
Length = 1706
Score = 662 bits (1708), Expect = 0.0
Identities = 475/1613 (29%), Positives = 813/1613 (50%), Gaps = 107/1613 (6%)
Query: 30 KEDIYSHLTSVIQNTDILDDAIVQRLIYYASKDMRDNNMLREIRM--LAGEVLVSLAAHD 87
K +IY+ L +IQ L++ VQRL+ ASK+MR+ + +A + LV+L+ +
Sbjct: 128 KVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNH 187
Query: 88 FNSVMYEVQSNFRILELPDEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERM 147
F+ VMYE+Q + + L L DEFV++ LA+LA V + +P+M +TL T+ TMLRLA + ++
Sbjct: 188 FSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKI 247
Query: 148 KGTFCIALEKFSKAIYKYVNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTL 207
+ C A+E F + + Y+ H + YP + + K+F ++ Y + W +P L
Sbjct: 248 RQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHHNPEVKL 307
Query: 208 SIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIG 267
++K+ P + LLL +D R +P LL +Y+ VTQ L+QIL +V +
Sbjct: 308 GVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEALFVTQVLRQILGLSVTTNTP 367
Query: 268 LPRSLRRSIFINLLQQICR---APEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRS 324
+P+ +IF L Q+C A +N M+ CF+ LA S P ELM+FF Q+ +
Sbjct: 368 VPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMET 427
Query: 325 NNEAIRVGILTLLRLAVNADEPRLRDHIISIE-RTVKIVMGDLSTKVRNSVLLLIQTMCE 383
N EA+RVG L L+R V+ADEPR+ I + R VK + D +KVR ++L +I +
Sbjct: 428 NKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQLAL 487
Query: 384 KSYIEAREGWPL----IDYVFSQFATLNRNLEKPVKTNFHENEKEEESVRETSLEVLKTL 439
Y E +GW L + S + NR + F++ + EE V + +++ +K +
Sbjct: 488 CGYQERIKGWGLKYLSVQLTLSTYKLTNR------REKFYQRDLEERMVHKVTMDTVKII 541
Query: 440 DPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMAEEKKQHSAKESTALVVSTG 499
V GM W R+L +++ +Y EAL P+ I + +AE + H ++ +
Sbjct: 542 TSSVSGMTTEFWVRLLCYIMETDYVEALTPI--CISLTNLAEH-QLHGQDVDVSVAGKSR 598
Query: 500 AVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEIIHPKLVDLWKTRLPELLQP 559
V LP+PQ+LLARLLV+ GE RG + LL+ L + I P + D+W+ + L++
Sbjct: 599 QVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRY 658
Query: 560 LEGKNIST---VLWETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLW 616
LE T WE L+Q L+ SL K +W+++L+++ Q+ S+ + S EK FL+
Sbjct: 659 LEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLY 718
Query: 617 KALGTTLACCQDSDFVNSQIKEFLTAPNQLGD-QRQGITSILGYCAENHLDIVLKVLKTF 675
+ALG TLA ++ V + E L + D +G+ G CA + VL VL F
Sbjct: 719 RALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDF 778
Query: 676 -----QNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVL 730
++++ + ++ + ++ K+ +MV+Y VA + + LL+ ++ I ++++
Sbjct: 779 EERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKII 838
Query: 731 SLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAED-QGFQFSYKEMLIGYMLDF 789
+ Q D+ L+M+F +S+ ++ A+ + +D + F F+ K L ++
Sbjct: 839 HHYVSSCQ---------DICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAV 889
Query: 790 IRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEG 849
I+ EP D+L SP+R A+ A+ +LSKLKP S +++ +++ +I ++ L L E
Sbjct: 890 IKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISL----QLPGE- 944
Query: 850 QTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERERAF 909
D E I+ LY ++ +L +L+++++ ++ + QEM LL+ W++S+KEWERE+A
Sbjct: 945 ----DNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAV 1000
Query: 910 QI---TAKVLTNDIEAPENFKI---GSLLGLLAPHSCDTLPTIRQAA---ASSTIGLFYI 960
+ ++ + + K+ G+++GL+AP +CD R A+ SS + L
Sbjct: 1001 SLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHAS 1060
Query: 961 KGIHL----EVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGL 1016
+ L + + L+ + L+S DV+ SS+IAK+V +E++ ++++ +
Sbjct: 1061 QTCSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENT 1120
Query: 1017 ESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQ 1076
++N KA W+ L+ + LED++ EIL I H+PV+ E + +++ I
Sbjct: 1121 GAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR-RLLIDGILL 1179
Query: 1077 IASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDI--- 1133
+A H +T++ +LL++PLP + +W A++E + +L +L+ +L++ L I
Sbjct: 1180 LAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISAT 1239
Query: 1134 --------ARVEAISVACAMYEVISM---GTSVTGLYPEL-FTLLLKLVSCTLGQKMLTC 1181
A V+ + C ++ +I + P+L +TLLL+L S
Sbjct: 1240 SKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGS---------- 1289
Query: 1182 PWSHRRH-------VMQQGEQQQIPDPCRLSTATLKCLQAQAMR---EGLAKESDEGDNL 1231
SHR + + +P+ L T+K +Q R + LA DE +
Sbjct: 1290 --SHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDE-QAV 1346
Query: 1232 WTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSELMK 1291
W LL T GV LAR G + E +L + S + RI+ A E M
Sbjct: 1347 WDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMS 1406
Query: 1292 EPILWKHGNLRNVLILMDQSA-WDSNATLRQMAIRGLGNTASGAPHKVKKHKQLMLESII 1350
P+L++ L+ +L+++ A + + LR +++R LGN A GAP KVK++++++LE +
Sbjct: 1407 GPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCL 1466
Query: 1351 RGLYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFL 1410
L V E ++AL KIL L + DV F + Q R FF++E + +RL A L
Sbjct: 1467 GPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFIL 1526
Query: 1411 FEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMVCIPFLG---LQE 1467
F LA + G K FF E+KK+ I +LH DP AC + C+ F G L+
Sbjct: 1527 FGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEH 1586
Query: 1468 LYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQEILWILHTHSFTFFTSTWEVIRSAAVKL 1527
G D D + F C L +K +L+ + + + IR AA L
Sbjct: 1587 PSGPSDTATDD---KMTVFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNL 1643
Query: 1528 TDAVVLNLTSQYVELLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKE 1580
++ +++ Y++ LD L LQ L+ DP V+RAA L T+L C +
Sbjct: 1644 AGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETL-TVLDSCSQ 1695
>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
Length = 1710
Score = 656 bits (1692), Expect = 0.0
Identities = 474/1617 (29%), Positives = 814/1617 (50%), Gaps = 111/1617 (6%)
Query: 30 KEDIYSHLTSVIQNTDILDDAIVQRLIYYASKDMRDNNMLREIRM--LAGEVLVSLAAHD 87
K +IY+ L +IQ L++ VQRL+ ASK+MR+ + +A + LV+L+ +
Sbjct: 128 KVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNH 187
Query: 88 FNSVMYEVQSNFRILELPDEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERM 147
F+ VMYE+Q + + L L DEFV++ LA+LA V + +P+M +TL T+ TMLRLA + ++
Sbjct: 188 FSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKI 247
Query: 148 KGTFCIALEKFSKAIYKYVNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTL 207
+ C A+E F + + Y+ H + YP + + K+F ++ Y + W +P L
Sbjct: 248 RQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHYNPEVKL 307
Query: 208 SIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIG 267
++K+ P + LLL +D R +P LL +Y+ VTQ L+QIL +V +
Sbjct: 308 GVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILELSVTTNTP 367
Query: 268 LPRSLRRSIFINLLQQICR---APEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRS 324
+P+ +IF L Q+C A +N M+ CF+ LA S P ELM+FF Q+ +
Sbjct: 368 VPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMET 427
Query: 325 NNEAIRVGILTLLRLAVNADEPRLRDHIISIE-RTVKIVMGDLSTKVRNSVLLLIQTMCE 383
N EA+RVG L L+R V+ADEPR+ I + R VK + D +KVR ++L +I +
Sbjct: 428 NKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQLAL 487
Query: 384 KSYIEAREGWPL----IDYVFSQFATLNRNLEKPVKTNFHENEKEEESVRETSLEVLKTL 439
Y E +GW L + S + NR + F++ + EE V + +++ +K +
Sbjct: 488 CGYQERIKGWGLKYLSVQLTLSTYKLTNR------REKFYQRDLEERMVHKVTMDTVKII 541
Query: 440 DPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMAEEKKQHSAKESTALVVSTG 499
V GM W R+L +++ +Y EAL P+ I + +AE + H ++ +
Sbjct: 542 TSSVSGMTTEFWVRLLCYIMETDYVEALTPI--CISLTNLAEH-QLHGQDVDVSVAGKSR 598
Query: 500 AVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEIIHPKLVDLWKTRLPELLQP 559
V LP+PQ+LLARLLV+ GE RG + LL+ L + I P + D+W+ + L++
Sbjct: 599 QVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRY 658
Query: 560 LEGKNIST---VLWETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLW 616
LE T WE L+Q L+ SL K +W+++L+++ Q+ S+ + S EK FL+
Sbjct: 659 LEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLY 718
Query: 617 KALGTTLACCQDSDFVNSQIKEFLTAPNQLGD-QRQGITSILGYCAENHLDIVLKVLKTF 675
+ALG TLA ++ V + E L + D +G+ G CA + VL VL F
Sbjct: 719 RALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDF 778
Query: 676 -----QNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVL 730
++++ + ++ + ++ K+ +MV+Y VA + + LL+ ++ I ++++
Sbjct: 779 EERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKII 838
Query: 731 SLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAED-QGFQFSYKEMLIGYMLDF 789
+ Q D+ L+M+F +S+ ++ A+ + +D + F F+ K L ++
Sbjct: 839 HHYVSSCQ---------DICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAV 889
Query: 790 IRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEG 849
I+ EP D+L SP+R A+ A+ +LSKLKP S +++ +++ +I ++ L L E
Sbjct: 890 IKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISL----QLPGE- 944
Query: 850 QTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERERAF 909
D E I+ LY ++ +L +L+++++ ++ + QEM LL+ W++S+KEWERE+A
Sbjct: 945 ----DNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAV 1000
Query: 910 QITAKVLTNDIEAP------ENFKIGSLLGLLAPHSCDTLPTIRQAA---ASSTIGLFYI 960
+ ++ + + + + G+++GL+AP +CD R A+ SS + L
Sbjct: 1001 SLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHAS 1060
Query: 961 KGIHL----EVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGL 1016
+ L + + L+ + L+S DV+ SS+IAK+V +E++ ++++ +
Sbjct: 1061 QTCSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENT 1120
Query: 1017 ESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQ 1076
++N KA W+ L+ + LED++ EIL I H+PV+ E + +++ I
Sbjct: 1121 GAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR-RLLIDGILL 1179
Query: 1077 IASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDI--- 1133
+A H +T++ +LL++PLP + +W A++E + +L +L+ +L++ L I
Sbjct: 1180 LAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISAT 1239
Query: 1134 --------ARVEAISVACAMYEVISM---GTSVTGLYPEL-FTLLLKLVSCTLGQKMLTC 1181
A V+ + C ++ +I + P+L +TLLL+L S
Sbjct: 1240 SKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGS---------- 1289
Query: 1182 PWSHRRH-------VMQQGEQQQIPDPCRLSTATLKCLQAQAMR---EGLAKESDEGDNL 1231
SHR + + +P+ L T+K +Q R + LA DE +
Sbjct: 1290 --SHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDE-QAV 1346
Query: 1232 WTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSEL-- 1289
W LL T GV LAR G + E +L + S + RI+ A E+
Sbjct: 1347 WDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRH 1406
Query: 1290 --MKEPILWKHGNLRNVLILMDQSA-WDSNATLRQMAIRGLGNTASGAPHKVKKHKQLML 1346
M P+L++ L+ +L+++ A + + LR +++R LGN A GAP KVK++++++L
Sbjct: 1407 RFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLL 1466
Query: 1347 ESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLT 1406
E + L V E ++AL KIL L + DV F + Q R FF++E + +RL
Sbjct: 1467 EKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLK 1526
Query: 1407 AIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMVCIPFLG-- 1464
A LF LA + G K FF E+KK+ I +LH DP AC + C+ F G
Sbjct: 1527 AFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWK 1586
Query: 1465 -LQELYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQEILWILHTHSFTFFTSTWEVIRSA 1523
L+ G D D + F C L +K +L+ + + + IR A
Sbjct: 1587 SLEHPSGPSDTATDD---KMTVFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIA 1643
Query: 1524 AVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKE 1580
A L ++ +++ Y++ LD L LQ L+ DP V+RAA L T+L C +
Sbjct: 1644 ACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETL-TVLDSCSQ 1699
>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
Length = 1723
Score = 644 bits (1662), Expect = 0.0
Identities = 473/1620 (29%), Positives = 813/1620 (50%), Gaps = 104/1620 (6%)
Query: 30 KEDIYSHLTSVIQNTDILDDAIVQRLIYYASKDMRDNNMLREIRM--LAGEVLVSLAAHD 87
K +IY+ L +IQ L++ VQRL+ ASK+MR+ + +A + LV+L+ +
Sbjct: 128 KVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNH 187
Query: 88 FNSVMYEVQSNFRILELPDEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERM 147
F+ VMYE+Q + + L L DEFV++ LA+LA V + +P+M +TL T+ TMLRLA + ++
Sbjct: 188 FSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKI 247
Query: 148 KGTFCIALEKFSKAIYKYVNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTL 207
+ C A+E F + + Y+ H + YP + + K+F ++ Y + W +P L
Sbjct: 248 RQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHHNPEVKL 307
Query: 208 SIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQYKDK---EIDFHVTQSLKQILTAAVLY 264
++K+ P + LLL +D R +P LL +Y+ K + Q L+QIL +V
Sbjct: 308 GVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQILGLSVTT 367
Query: 265 DIGLPRSLRRSIFINLLQQICR---APEPPVKENEMKASSCFLILAHSNPGELMEFFDEQ 321
+ +P+ +IF L Q+C A +N M+ CF+ LA S P ELM+FF Q
Sbjct: 368 NTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQ 427
Query: 322 VRSNNEAIRVGILTLLRLAVNADEPRLRDHIISIE-RTVKIVMGDLSTKVRNSVLLLIQT 380
+ +N EA+RVG L L+R V+ADEPR+ I + R VK + D +KVR ++L +I
Sbjct: 428 METNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQ 487
Query: 381 MCEKSYIEAREGWPL----IDYVFSQFATLNRNLEKPVKTNFHENEKEEESVRETSLEVL 436
+ Y E +GW L + S + NR + F++ + EE V + +++ +
Sbjct: 488 LALCGYQERIKGWGLKYLSVQLTLSTYKLTNR------REKFYQRDLEERMVHKVTMDTV 541
Query: 437 KTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMAEEKKQHSAKESTALVV 496
K + V GM W R+L +++ +Y EAL P+ I + +AE + H ++
Sbjct: 542 KIITSSVSGMTTEFWVRLLCYIMETDYVEALTPI--CISLTNLAEH-QLHGQDVDVSVAG 598
Query: 497 STGAVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEIIHPKLVDLWKTRLPEL 556
+ V LP+PQ+LLARLLV+ GE RG + LL+ L + I P + D+W+ + L
Sbjct: 599 KSRQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALL 658
Query: 557 LQPLEGKNIST---VLWETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKK 613
++ LE T WE L+Q L+ SL K +W+++L+++ Q+ S+ + S EK
Sbjct: 659 VRYLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKG 718
Query: 614 FLWKALGTTLACCQDSDFVNSQIKEFLTAPNQLGD-QRQGITSILGYCAENHLDIVLKVL 672
FL++ALG TLA ++ V + E L + D +G+ G CA + VL VL
Sbjct: 719 FLYRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVL 778
Query: 673 KTF-----QNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIIS 727
F ++++ + ++ + ++ K+ +MV+Y VA + + LL+ ++ I +
Sbjct: 779 HDFEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITA 838
Query: 728 QVLSLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAED-QGFQFSYKEMLIGYM 786
+++ + Q D+ L+M+F +S+ ++ A+ + +D + F F+ K L +
Sbjct: 839 KIIHHYVSSCQ---------DICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSII 889
Query: 787 LDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLK 846
+ I+ EP D+L SP+R A+ A+ +LSKLKP S +++ +++ +I ++ L L
Sbjct: 890 VAVIKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISL----QLP 945
Query: 847 SEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERE 906
E D E I+ LY ++ +L +L+++++ ++ + QEM LL+ W++S+KEWERE
Sbjct: 946 GE-----DNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWERE 1000
Query: 907 RAFQI---TAKVLTNDIEAPENFKI---GSLLGLLAPHSCDTLPTIRQAA---ASSTIGL 957
+A + ++ + + K+ G+++GL+AP +CD R A+ SS + L
Sbjct: 1001 KAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDL 1060
Query: 958 FYIKGIHL----EVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEML 1013
+ L + + L+ + L+S DV+ SS+IAK+V +E++ ++++
Sbjct: 1061 HASQTCSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLC 1120
Query: 1014 DGLESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEA 1073
+ ++N KA W+ + L+ + LED++ EIL I H+PV+ E + +++
Sbjct: 1121 ENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR-RLLIDG 1179
Query: 1074 ISQIASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDI 1133
I +A H +T++ +LL++PLP + +W A++E + +L +L+ +L++ L I
Sbjct: 1180 ILLLAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRI 1239
Query: 1134 -----------ARVEAISVACAMYEVISM---GTSVTGLYPEL-FTLLLKLVSCTLGQKM 1178
A V+ + C ++ +I + P+L +TLLL+L S +
Sbjct: 1240 SATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAA 1299
Query: 1179 --LTCPWSHRRHVMQQGEQQQIPDPCRLSTATLKCLQAQAMR---EGLAKESDEGDNLWT 1233
+ W H E+ + C T+K +Q R + LA DE +W
Sbjct: 1300 PPVLKMWK-LVHTTPLPEEMNL-QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDE-QAVWD 1356
Query: 1234 LLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSELMKEP 1293
LL T GV LAR G + E +L + S + RI+ A E M P
Sbjct: 1357 LLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGP 1416
Query: 1294 ILWKHGNLRNVLILMDQSA-WDSNATLRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRG 1352
+L++ L+ +L+++ A + + LR +++R LGN A GAP KVK++++++LE +
Sbjct: 1417 VLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGP 1476
Query: 1353 LYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFE 1412
L V E ++AL KIL L + DV F + Q R FF++E + +RL A LF
Sbjct: 1477 LREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFG 1536
Query: 1413 DLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMVCIPFLG---LQELY 1469
LA + G K FF E+KK+ I +LH DP AC + C+ F G L+
Sbjct: 1537 KLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPS 1596
Query: 1470 GVLDRLLDQDLPRARDFYRQFCVKLAKK---------NQEILWILHTHSFTFFTSTWEVI 1520
G D D + F C L +K +L+ + + + I
Sbjct: 1597 GPSDTTTDD---KMTIFQTTMCSILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRI 1653
Query: 1521 RSAAVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKE 1580
R AA L ++ +++ Y++ LD L LQ L+ DP V+RAA L T+L C +
Sbjct: 1654 RIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETL-TVLDSCSQ 1712
>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
Length = 1641
Score = 603 bits (1554), Expect = e-172
Identities = 452/1586 (28%), Positives = 770/1586 (48%), Gaps = 82/1586 (5%)
Query: 47 LDDAIVQRLIYYASKDM-RDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELP 105
LD +I AS +M + +++ + + A VLV++ + VM E+ LP
Sbjct: 80 LDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLP 139
Query: 106 DEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSKAIYKY 165
V+ LA L+ + +PF+ L ++ +L +A+ + ++ FC AL++FS+ +Y
Sbjct: 140 HCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGALEY 199
Query: 166 VNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVSLLLHRED 225
+ + P P + + + IF + + +W L++V+A GP +S LL E
Sbjct: 200 LANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGP-MSHLLPSER 258
Query: 226 FRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSIFINLLQQIC 285
+P +L YK F++++SL QIL AAV + ++ L QIC
Sbjct: 259 LEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQIC 318
Query: 286 ---RAPEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRSNNEAIRVGILTLLRLAVN 342
+ P V N+ + CF +LA S+P L+ F ++ ++NE RVG L ++R +N
Sbjct: 319 VPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVIN 378
Query: 343 ADEPRLRDHIISIERTVKIVMGDLSTKVRNSVLLLIQTMCEKSYIEAREGWPLIDYVFSQ 402
+ ++ D I ++++ + D ++KV+ +V+ +I M Y+E G +I+Y+ Q
Sbjct: 379 SAAAQMEDKKPFILSSMRLPLLDTNSKVKRAVVQVISAMAHHGYLEQPGGEAMIEYIVQQ 438
Query: 403 FATLNRNLEKPVKTNFHENEKEEESVRETSLEVLKTLDPLVIGMPQVLWPRILTFVVPAE 462
A ++P K + + +SVR S+ L + V M VLWP +L F+ P
Sbjct: 439 CALPPE--QEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVR 496
Query: 463 YTEALEPLFSIIRILIMAEEKKQHSAKESTALVVSTGAVKLPSPQQLLARLLVISMPASL 522
+T AL PL R L+ +K+Q + ++ L+ LPSP + RLLV+S L
Sbjct: 497 FTGALTPL---CRSLVHLAQKRQEAGADA-FLIQYDAHASLPSPYAVTGRLLVVSSSPYL 552
Query: 523 GELRGAGAIGLLKILPEIIHPKLVDLWKTRLPELLQPLEGKNISTV---LWETMLLQLLK 579
G+ RGA A+ LL +L IHP L W+T +P LL L+ T+ WE LL L+
Sbjct: 553 GDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFLR 612
Query: 580 ESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLWKALGTTLACCQDSDFVNSQIKEF 639
++L ISD AW QL+ + +Q+ Y EK FL+K +GTTL + V ++E
Sbjct: 613 DTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQEL 672
Query: 640 L-TAPNQLGDQRQGITSILGYCAENHLDIVLKVLKTFQNQEKF-----FMNRCKSLFSGK 693
L TA Q +R+G+ G CA +HL+ L L+ F E F +N K +
Sbjct: 673 LETARYQEEAEREGLACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENE 732
Query: 694 KSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVLSLHGQCSQVLGMSVMNKDMDLQM 753
K+ +++ YG VA AP++ +L+++ DI+ + ++VLG+ V KD L++
Sbjct: 733 VEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFS--TKVLGIKVETKDPALKL 790
Query: 754 SFTRSITEIGIAVQDAEDQG-FQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRY 812
+S+ + A+ + G F F+ K L+ M++FIR EP DSL +PIR KA++ Y
Sbjct: 791 CLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTY 850
Query: 813 LSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEGQTDKDKEHIQFLYERSMDALGKL 872
L ++P L Q +++ + ++ L P E + +G K LY ++ AL L
Sbjct: 851 LVSVEPALDEQARADVIHGCLHSIMALLP-EPKEEDGGCQKS------LYLETLHALEDL 903
Query: 873 LKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERERAFQITAKVLTNDIE------APENF 926
L +++ N+ + Q M L W+ S + ER RA ++A +L +E
Sbjct: 904 LTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRVSALVPFH 963
Query: 927 KIGSLLGLLAPHSCDTLPTIRQAAASSTIGLFYI----KGIHLE-----VERLQGLQEGL 977
+G L+GL +P D P RQ A L Y+ +G + ERL L++GL
Sbjct: 964 NLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGL 1023
Query: 978 ESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCTKACGIWMITVLKQ 1037
D + + +I++K +P ++++ L M + L C++A + + +L++
Sbjct: 1024 VHPDPAILFHTCHSVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQE 1083
Query: 1038 QGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASFHMDTVVVNLLQKPLPFD 1097
+G L++++ EI+ + + Q E ++ +A+ H VV +LL PLP D
Sbjct: 1084 RGGVLQEKVPEIVSVLRSKLQE-AQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLD 1142
Query: 1098 RDTKTLWKALAEKPASSGKLLQALIDKLETEL-------------EDDIARVEAISVACA 1144
T LW+ALA +P + ++L L++K+ ++ D +A + +S CA
Sbjct: 1143 SHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCA 1202
Query: 1145 MYEVIS---MGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDP 1201
++EV+S G +V LYP+LF +LL VSCT+G ++ + R + +P
Sbjct: 1203 LFEVMSTPAAGPAVLELYPQLFVVLLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEP 1262
Query: 1202 CRLSTATLKCLQAQAMREGLAKESD-EGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVI 1260
C + TL+ + ++ E + + D EG W LL + + H G LAR+MA +
Sbjct: 1263 CSSAVDTLRSMLLRSGSEDVVQRMDLEGG--WELLRTSAGHEEGATRLARAMAEHAGPRL 1320
Query: 1261 LDIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQ-------SAW 1313
+++ L + +S+ EN R+T AF +EL+ + N+ N L+L+D
Sbjct: 1321 PLVLKTLACTHSSAYENQRVTTTAFLAELL-------NSNVANDLMLLDSLLESLAARQK 1373
Query: 1314 DSNATLRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGL--YHLARTEVVCESLKALKK 1371
D+ A++R++ +RGL N ASG P KV+ H +L ++I GL + V E++ L +
Sbjct: 1374 DTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLGLAR 1433
Query: 1372 ILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIK 1431
++ L+ D+ + ++ R FF+ E+ + R +I LF L + + F +++
Sbjct: 1434 LVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVV 1493
Query: 1432 KSLISFLLHLWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLP-RARDFYRQF 1490
L LLHL DP + ACR L +C P L +EL + L + +F
Sbjct: 1494 GGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTT 1553
Query: 1491 CVKLAKKNQEILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTT 1550
C L ++L L T +F S+WE +R+AA T +VL+ + +D +QL
Sbjct: 1554 CKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDLDQLIA 1613
Query: 1551 RLQALRQDPCISVQRAAEAALQTLLR 1576
LQ L +DP V+ A AL L++
Sbjct: 1614 ALQILLKDPAPEVRTRAAEALGRLVK 1639
>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
[Homo sapiens]
Length = 1218
Score = 483 bits (1244), Expect = e-136
Identities = 357/1217 (29%), Positives = 592/1217 (48%), Gaps = 75/1217 (6%)
Query: 412 KPVKTNFHENEKEEESVRETSLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLF 471
KP K + + +SVR S+ L + V M VLWP +L F+ P +T AL PL
Sbjct: 23 KPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPL- 81
Query: 472 SIIRILIMAEEKKQHSAKESTALVVSTGAVKLPSPQQLLARLLVISMPASLGELRGAGAI 531
R L+ +K+Q + ++ + A LPSP + RLLV+S LG+ RGA A+
Sbjct: 82 --CRSLVHLAQKRQEAGADAFLIQYDAHA-SLPSPYAVTGRLLVVSSSPYLGDGRGAAAL 138
Query: 532 GLLKILPEIIHPKLVDLWKTRLPELLQPLEGKNISTVL---WETMLLQLLKESLWKISDV 588
LL +L IHP L W+T +P LL L+ T+ WE LL L+++L ISD
Sbjct: 139 RLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFLRDTLAIISDN 198
Query: 589 AWTIQLTQDFKQQMGSYSNNSTEKKFLWKALGTTLACCQDSDFVNSQIKEFL-TAPNQLG 647
AW QL+ + +Q+ Y EK FL+K +GTTL + V ++E L TA Q
Sbjct: 199 AWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEE 258
Query: 648 DQRQGITSILGYCAENHLDIVLKVLKTFQNQEKF-----FMNRCKSLFSGKKSLTKTDVM 702
+R+G+ G CA +HL+ L L+ F E F +N K + K+ ++
Sbjct: 259 AEREGLACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENEVEKVKSALI 318
Query: 703 VIYGAVALHAPKKQLLSRLNQDIISQVLSLHGQCSQVLGMSVMNKDMDLQMSFTRSITEI 762
+ YG VA AP++ +L+++ DI+ + ++VLG+ V KD L++ +S+ +
Sbjct: 319 LCYGHVAARAPRELVLAKVESDILRNICQHFS--TKVLGIKVETKDPALKLCLVQSVCMV 376
Query: 763 GIAVQDAEDQG-FQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLS 821
A+ + G F F+ K L+ M++FIR EP DSL +PIR KA++ YL ++P L
Sbjct: 377 SRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALD 436
Query: 822 LQDHLNILEENIRRLLPLPPLENLKSEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNV 881
Q +++ + ++ L P E + +G K LY ++ AL LL +++ N+
Sbjct: 437 EQARADVIHGCLHSIMALLP-EPKEEDGGCQKS------LYLETLHALEDLLTSLLQRNM 489
Query: 882 NAEDCQEMFNLLQMWLVSQKEWERERAFQITAKVLTNDIE------APENFKIGSLLGLL 935
+ Q M L W+ S + ER RA ++A +L +E +G L+GL
Sbjct: 490 TPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLF 549
Query: 936 APHSCDTLPTIRQAAASSTIGLFYI----KGIHLE-----VERLQGLQEGLESDDVQVQI 986
+P D P RQ A L Y+ +G + ERL L++GL D +
Sbjct: 550 SPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILF 609
Query: 987 KISSKIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCTKACGIWMITVLKQQGAALEDQL 1046
+ +I++K +P ++++ L M + L C++A + + +L+++G L++++
Sbjct: 610 HTCHSVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKV 669
Query: 1047 LEILGTIYHHMPVLRQKEESFQFILEAISQIASFHMDTVVVNLLQKPLPFDRDTKTLWKA 1106
EI+ + + Q E ++ +A+ H VV +LL PLP D T LW+A
Sbjct: 670 PEIVSVLRSKLQE-AQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTCMLWRA 728
Query: 1107 LAEKPASSGKLLQALIDKLETEL-------------EDDIARVEAISVACAMYEVIS--- 1150
LA +P + ++L L++K+ ++ D +A + +S CA++EV+S
Sbjct: 729 LAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPA 788
Query: 1151 MGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCRLSTATLK 1210
G +V LYP+LF +LL VSCT+G ++ + R + +PC + TL+
Sbjct: 789 AGPAVLELYPQLFVVLLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSSAVDTLR 848
Query: 1211 CLQAQAMREGLAKESD-EGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLS 1269
+ ++ E + + D EG W LL + + H G LAR+MA + +++ L
Sbjct: 849 SMLLRSGSEDVVQRMDLEGG--WELLRTSAGHEEGATRLARAMAEHAGPRLPLVLKTLAC 906
Query: 1270 SLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQ-------SAWDSNATLRQM 1322
+ +S+ EN R+T AF +EL+ + N+ N L+L+D D+ A++R++
Sbjct: 907 THSSAYENQRVTTTAFLAELL-------NSNVANDLMLLDSLLESLAARQKDTCASVRRL 959
Query: 1323 AIRGLGNTASGAPHKVKKHKQLMLESIIRGL--YHLARTEVVCESLKALKKILELLTDRD 1380
+RGL N ASG P KV+ H +L ++I GL + V E++ L +++ L+ D
Sbjct: 960 VLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWD 1019
Query: 1381 VSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLH 1440
+ + ++ R FF+ E+ + R +I LF L + + F +++ L LLH
Sbjct: 1020 LRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLH 1079
Query: 1441 LWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLP-RARDFYRQFCVKLAKKNQ 1499
L DP + ACR L +C P L +EL + L + +F C L
Sbjct: 1080 LQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFP 1139
Query: 1500 EILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDP 1559
++L L T +F S+WE +R+AA T +VL+ + +D +QL LQ L +DP
Sbjct: 1140 DLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDLDQLIAALQILLKDP 1199
Query: 1560 CISVQRAAEAALQTLLR 1576
V+ A AL L++
Sbjct: 1200 APEVRTRAAEALGRLVK 1216
>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
Length = 1318
Score = 196 bits (498), Expect = 1e-49
Identities = 251/1102 (22%), Positives = 441/1102 (40%), Gaps = 133/1102 (12%)
Query: 570 WETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLWKALGTTLACCQDS 629
WE L+Q+ +S+ +S W+ +L + S EK FL+ G L ++
Sbjct: 244 WEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAEKNG 303
Query: 630 DFVNSQIKEFLTAPNQLGDQRQGITSILGYCAENHLDIVLKVLKTFQNQEKFFMNRCKSL 689
V ++ L +Q QR+G+ LG A HLD V VL F + S
Sbjct: 304 ATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLPSSS 363
Query: 690 FSGKKSL----TKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVLSLHGQCSQVLGMSVM 745
+ L + +++ YG VA A + +L ++ + V H
Sbjct: 364 PKNSEDLRWKWASSTILLAYGQVAAKA-RAHILPWVDNIVSRMVFYFH----------YS 412
Query: 746 NKDMDLQMSF-TRSITEIGIAVQDAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRW 804
+ D L+ SF T ++ +G + ++F L+ ++ + EP D+L + R
Sbjct: 413 SWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQ 472
Query: 805 KALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSE---------------- 848
+A+ L KL+P + L+ +L R + LP L+ L+
Sbjct: 473 QAMHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVA 532
Query: 849 ----GQTDKD---------KEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQM 895
G T + EH+Q LY R+M+AL +L++++ N A++ + + L +
Sbjct: 533 RERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYI 592
Query: 896 WLVSQKEWERERAFQ---ITAKVLTND--IEAPENFK-IGSLLGLLAPHSCDTLPTIRQA 949
WL S+K ER+RA I K L ++ ++ E+FK IG L+G+L D ++
Sbjct: 593 WLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRC 652
Query: 950 AASSTIGLFYIKGIHLEVERLQ------------------------------GLQEGLES 979
+ L+ + H E LQ G QE ++
Sbjct: 653 SLEGASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKN 712
Query: 980 DDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCTKACGIWMITVLKQQG 1039
Q+ S ++ K + + + E+ + +DGL S +P +A ++T +++ G
Sbjct: 713 HIFQL---CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHG 769
Query: 1040 AALE--DQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASFHMDTVVVNLLQKPLPFD 1097
A LE + + + + + + KE++ L AI+ +A H +V L +P D
Sbjct: 770 AKLEIVSSMAQAIRLRLCSVHIPQAKEKT----LHAITLLARSHTCELVATFLNISIPLD 825
Query: 1098 RDTKTLWKALAEKPASSGKLLQALIDKLE-----TELEDD---------IARVEAISVAC 1143
T LW+AL +S +L L+ L+ T D + + A+++
Sbjct: 826 SHTFQLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLH 885
Query: 1144 AMYEVISMGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCR 1203
+ +V YP+LF LL + L + + P QQ ++ +P P
Sbjct: 886 ELQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEP-----QPKQQAQEAAVPSPQS 940
Query: 1204 LSTATLKCLQAQAMREGLAKESD--EGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVIL 1261
ST+ L+ L++ G + E W L ++ T+ GV LAR+M I
Sbjct: 941 CSTS-LEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIP 999
Query: 1262 DIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQ 1321
++ QLL SL S E R ++ + P+L + + L ++ Q D + +R
Sbjct: 1000 AVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRV 1059
Query: 1322 MAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDV 1381
++++GL N P K Q L ++ G + + +VC + + L L +
Sbjct: 1060 LSLQGLSNILFH-PDKGSL-LQGQLRPLLDGFFQSSDQVIVC-IMGTVSDTLHRLGAQGT 1116
Query: 1382 SFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHL 1441
+ + TR+FF DE+D +R A+ LF DL R ++ +S++ LLHL
Sbjct: 1117 GSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHL 1176
Query: 1442 WDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLPRARDF---------YRQFCV 1492
D P + + C L + L+ + L + AR F +F +
Sbjct: 1177 KDQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSI 1236
Query: 1493 KLAKKNQEILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRL 1552
L+ + L LH+HS TW + + T Q + +D L
Sbjct: 1237 HLS----QALSYLHSHS--CHIKTWVTL---FIGHTICYHPQAVFQMLNAVDTNLLFRTF 1287
Query: 1553 QALRQDPCISVQRAAEAALQTL 1574
+ LR DP S++ A + L L
Sbjct: 1288 EHLRSDPEPSIREFATSQLSFL 1309
>gi|223278410 hypothetical protein LOC374977 [Homo sapiens]
Length = 1323
Score = 150 bits (379), Expect = 9e-36
Identities = 203/845 (24%), Positives = 360/845 (42%), Gaps = 65/845 (7%)
Query: 779 KEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLP 838
K+ +I ++ I++EPLDSL+S +R +A+ + LS +P L +++ ++ + +
Sbjct: 455 KKTMIKKIMRQIQEEPLDSLSSSVRKQAMEILTQLSHTQPTLGMRERSELVNVCVHSVFS 514
Query: 839 LPPLENLKSEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLV 898
LP ++ ++ + + E IQ LY ++++AL LLK + ++ + + L W+
Sbjct: 515 LPSVQAMQEKDEAKA--ETIQALYHQTLEALQTLLKALFIEDPTPAGLKSILEALGPWMN 572
Query: 899 SQKEWERERAFQITAKVLTNDIEAPENFK------IGSLLGLLAPHSCDTLPTIRQAAAS 952
S K ER RA VL + + F +G LLG L H D I A
Sbjct: 573 SGKAHERARAVNTNVSVLNHMLLTLPFFMPLGFPALGLLLGRLILHIGDPDEEIGCEALD 632
Query: 953 STIGLFYIKGIHLEVERLQGLQEGLESDDVQVQ----------IKISSKIAKIVSKF--- 999
I L+ I LE+++ +E ++ + I +++ +F
Sbjct: 633 GIIILYTI----LELQKRARDKEETNKKELYESNKHFLGPYNPVSPCQNILRVIEEFGDF 688
Query: 1000 IPNEEILMFLEEMLDGLESLNPTCTK--------ACGIWMITVLKQQGAALEDQLLEILG 1051
+ ++I L L+GL+ + K A + + +VL+ + + EI+
Sbjct: 689 LGPQQIKDLLLAALEGLKGSSEAPGKDSREMMQLASEVMLSSVLEWYRHRALEVIPEIMQ 748
Query: 1052 TIYHHMPVLRQKEESFQFILEAISQIASFHMDTVVVNLLQKPLPFDRDTKTLWKALAE-K 1110
IY + + Q+ + Q L +S +AS M VVV LL PLP + + +W+ L K
Sbjct: 749 GIYMQLSHI-QEPRARQVALLPVSLLASSFMTEVVVALLMCPLPLNSNGAEMWRQLILCK 807
Query: 1111 PASSGK-LLQALIDKLET-----ELEDDIARVEAISVACAMYEVISMGTSVTGLYPELFT 1164
P+ + LL L+ L+ E I + A S C + V S V +YP+L
Sbjct: 808 PSCDVRDLLDLLLGSLKEKPVTKEGRASIVPLAAASGLCELLSVNSCMGRVRRIYPQLLL 867
Query: 1165 LLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCRLSTATLKCLQAQAMREGLAKE 1224
LL V +G + C + ++G Q P P +K ++ +R G + E
Sbjct: 868 ALLIQVHYHIGLNLPGCVAPPKD--TKKGAQ---PSPFVPVRWVVKVVKTLLLRMGCSYE 922
Query: 1225 SD--EGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSENYRITG 1282
+ E W L+ +HH GV LAR+M + + I+ L+ L E +RIT
Sbjct: 923 TTFLEDQGGWELMEQVESHHRGVALLARAMVQYSCQELCRILYLLIPLLERGDEKHRITA 982
Query: 1283 AAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQMAIRGLGNTASGAPHKVKKHK 1342
AFF EL++ + + L M + + ++ ++IRGL A + K K K
Sbjct: 983 TAFFVELLQMEQVRRIPE-EYSLGRMAEGLSHHDPIMKVLSIRGLVILARRS-EKTAKVK 1040
Query: 1343 QLMLESIIRGLYHLARTEVVCESLKALKKIL----ELLTDRDVSFYFKEIVLQTRTFFED 1398
L L S+++GL ++ VV E++ LK + + L D V +I+L F D
Sbjct: 1041 AL-LPSMVKGLKNMDGMLVV-EAVHNLKAVFKGRDQKLMDSAVYVEMLQILL---PHFSD 1095
Query: 1399 EQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMV 1458
++ VR + I L+ + E++ +L+ LL + + N K+ C L+
Sbjct: 1096 AREVVRSSCINLYGKVVQKLRAPRTQAMEEQLVSTLVPLLLTMQEGNSKVSQKCVKTLLR 1155
Query: 1459 CIPFLGLQELYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQEILWILHTHSFTFFTSTWE 1518
C F+ + R + + + C L +++ +I + S + ++
Sbjct: 1156 CSYFMAWELPKRAYSR---KPWDNQQQTVAKICKCLVNTHRDSAFIFLSQSLEYAKNSRA 1212
Query: 1519 VIRSAAVKLTDAVVLNLTSQYVELLDR-EQLTTRLQALRQDPCISVQRAAEAALQTLLRR 1577
+R +V ++V + S E DR ++ L LR DP SV A +L
Sbjct: 1213 SLRKCSVMFIGSLVPCMESIMTE--DRLNEVKAALDNLRHDPEASVCIYAAQVQDHILAS 1270
Query: 1578 CKETS 1582
C + S
Sbjct: 1271 CWQNS 1275
>gi|187761375 maestro isoform a [Homo sapiens]
Length = 248
Score = 149 bits (377), Expect = 2e-35
Identities = 79/207 (38%), Positives = 122/207 (58%)
Query: 1263 IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQM 1322
I+ Q LS TS + R + +FFS++ + K L+NV ++ + A D +A R M
Sbjct: 8 ILGQPLSIPTSQPKQKRTSMISFFSKVSWKLRFQKREPLKNVFFILAERARDPSAKKRHM 67
Query: 1323 AIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVS 1382
A+R LG A AP KV+K+K+++L+ ++ GLY EV+ ES+K L +L + + +
Sbjct: 68 AMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLG 127
Query: 1383 FYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLW 1442
+F +I LQTRT +DE D +R +A LF LA GR+WK FF ++K++ S L+HL
Sbjct: 128 SFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQ 187
Query: 1443 DPNPKIGVACRDVLMVCIPFLGLQELY 1469
D NP++ AC+ C P+L L+E Y
Sbjct: 188 DRNPQVAKACKTTFQACSPYLKLKEEY 214
>gi|187761381 maestro isoform d [Homo sapiens]
Length = 262
Score = 142 bits (359), Expect = 2e-33
Identities = 75/203 (36%), Positives = 118/203 (58%), Gaps = 5/203 (2%)
Query: 1272 TSSSENYRITGAAFFSELMKEPILWK-----HGNLRNVLILMDQSAWDSNATLRQMAIRG 1326
+S E+ +G++ S L + + WK L+NV ++ + A D +A R MA+R
Sbjct: 26 SSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRN 85
Query: 1327 LGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFK 1386
LG A AP KV+K+K+++L+ ++ GLY EV+ ES+K L +L + + + +F
Sbjct: 86 LGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFI 145
Query: 1387 EIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNP 1446
+I LQTRT +DE D +R +A LF LA GR+WK FF ++K++ S L+HL D NP
Sbjct: 146 DITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNP 205
Query: 1447 KIGVACRDVLMVCIPFLGLQELY 1469
++ AC+ C P+L L+E Y
Sbjct: 206 QVAKACKTTFQACSPYLKLKEEY 228
>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapiens]
Length = 1052
Score = 142 bits (358), Expect = 3e-33
Identities = 166/732 (22%), Positives = 317/732 (43%), Gaps = 54/732 (7%)
Query: 768 DAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSL--QDH 825
D + F S+ ++ + +++E SL+S +R + + I LS L L +D
Sbjct: 207 DETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDR 266
Query: 826 LNILEENIRRLLPLPPLENLKSEGQTDKDKE-HIQFLYERSMDALGKLLKTMMWDNVNAE 884
+ I+ ++ LP + L + + + + LY ++ A ++L++++ + + E
Sbjct: 267 AELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLE 326
Query: 885 DCQEMFNLLQMWLVSQKEWERERAFQITAKVLTN-----DIEAPENF-KIGSLLGLLAPH 938
+ + L WL S K+ ERERA A+VL +++ P F ++G L+ L+A
Sbjct: 327 NLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALL 386
Query: 939 SCDTLPTIRQAAASSTIGLFYI----KGIHLEVERLQGLQEGLESDDVQVQIKISS---- 990
D + + AA L +I K I + + Q L+ L +++ S+
Sbjct: 387 CGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCF 446
Query: 991 -----KIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCT-KACGIWMITVLKQQGAALED 1044
+IA++ F+ + E+ F+ D L++L C ++ G ++T+ K + E
Sbjct: 447 YNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFE- 505
Query: 1045 QLLEILGTIYHHMPVLRQKEESFQFILEAISQIASF--HMDTVVVNLLQKPLPFDRDTKT 1102
++ EI+G I + ++ Q Q I+ +S S + D V+ LL P+P++R
Sbjct: 506 KVPEIMGVICAQLSIISQPRVRQQ-IINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAE 564
Query: 1103 LWKALAEKPASSGKLLQALIDKLE---TELEDDIARVEAISVACAMYEVI---SMGTSVT 1156
+W+ L+ + S+ +L L+ KL+ E + A++ A+YEV + +
Sbjct: 565 VWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAYVAVAATDALYEVFLGNRLRAATF 624
Query: 1157 GLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCRLSTATLKCLQAQA 1216
L+P+L LL + ++G M + Q+ + P + L+
Sbjct: 625 RLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQEVPSEVTPLCFAMQATKTLLLRTCC 684
Query: 1217 MREGLAKESDEGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSE 1276
++E E ++G W LL H G+ LA ++ + +M L+ L ++
Sbjct: 685 LQEFNIMEKNKG---WALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGND 741
Query: 1277 NYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAW--DSNATLRQMAIRGLGNTASGA 1334
+++T A FF EL++ P+ + ++ +V D W D N R + +RGL N
Sbjct: 742 KHKLTSAGFFVELLRSPVAKRLPSIYSVARFKD---WLQDGNHLFRILGLRGLYNLV--G 796
Query: 1335 PHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRT 1394
++++ + +L I+ L V L A++ +L+L+ D F + RT
Sbjct: 797 HQEMREDIKSLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMD----FTTLAAMMRT 848
Query: 1395 FFE---DEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVA 1451
F D + DV ++ LF K ++ SL+ LL+ D N +
Sbjct: 849 LFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEE 908
Query: 1452 CRDVLMVCIPFL 1463
R VL +C FL
Sbjct: 909 SRQVLTICAQFL 920
>gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]
Length = 422
Score = 107 bits (267), Expect = 9e-23
Identities = 81/301 (26%), Positives = 145/301 (48%), Gaps = 5/301 (1%)
Query: 47 LDDAIVQRLIYYASKDM-RDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELP 105
LD +I AS +M + +++ + + A VLV++ + VM E+ LP
Sbjct: 80 LDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLP 139
Query: 106 DEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSKAIYKY 165
V+ LA L+ + +PF+ L ++ +L +A+ + ++ FC AL++FS+ +Y
Sbjct: 140 HCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGALEY 199
Query: 166 VNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVSLLLHRED 225
+ + P P + + + IF + + +W L++V+A GP +S LL E
Sbjct: 200 LANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGP-MSHLLPSER 258
Query: 226 FRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSIFINLLQQIC 285
+P +L YK F++++SL QIL AAV + ++ L QIC
Sbjct: 259 LEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQIC 318
Query: 286 ---RAPEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRSNNEAIRVGILTLLRLAVN 342
+ P V N+ + CF +LA S+P L+ F ++ ++NE RVG L ++R +N
Sbjct: 319 VPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVIN 378
Query: 343 A 343
+
Sbjct: 379 S 379
>gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]
Length = 422
Score = 107 bits (267), Expect = 9e-23
Identities = 81/301 (26%), Positives = 145/301 (48%), Gaps = 5/301 (1%)
Query: 47 LDDAIVQRLIYYASKDM-RDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELP 105
LD +I AS +M + +++ + + A VLV++ + VM E+ LP
Sbjct: 80 LDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLP 139
Query: 106 DEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSKAIYKY 165
V+ LA L+ + +PF+ L ++ +L +A+ + ++ FC AL++FS+ +Y
Sbjct: 140 HCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGALEY 199
Query: 166 VNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVSLLLHRED 225
+ + P P + + + IF + + +W L++V+A GP +S LL E
Sbjct: 200 LANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGP-MSHLLPSER 258
Query: 226 FRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSIFINLLQQIC 285
+P +L YK F++++SL QIL AAV + ++ L QIC
Sbjct: 259 LEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQIC 318
Query: 286 ---RAPEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRSNNEAIRVGILTLLRLAVN 342
+ P V N+ + CF +LA S+P L+ F ++ ++NE RVG L ++R +N
Sbjct: 319 VPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVIN 378
Query: 343 A 343
+
Sbjct: 379 S 379
>gi|187761377 maestro isoform b [Homo sapiens]
Length = 196
Score = 85.9 bits (211), Expect = 3e-16
Identities = 49/136 (36%), Positives = 79/136 (58%)
Query: 1263 IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQM 1322
I+ Q LS TS + R + +FFS++ + K L+NV ++ + A D +A R M
Sbjct: 8 ILGQPLSIPTSQPKQKRTSMISFFSKVSWKLRFQKREPLKNVFFILAERARDPSAKKRHM 67
Query: 1323 AIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVS 1382
A+R LG A AP KV+K+K+++L+ ++ GLY EV+ ES+K L +L + + +
Sbjct: 68 AMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLG 127
Query: 1383 FYFKEIVLQTRTFFED 1398
+F +I LQTRT +D
Sbjct: 128 SFFIDITLQTRTLLDD 143
>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
Length = 719
Score = 85.9 bits (211), Expect = 3e-16
Identities = 132/583 (22%), Positives = 231/583 (39%), Gaps = 38/583 (6%)
Query: 1016 LESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAIS 1075
LE T+A + + + L+ +G LEDQ+ ++ + +P L + ++ L +S
Sbjct: 120 LEEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRP-WRAALRVLS 178
Query: 1076 QIASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDIAR 1135
+A H VV LL + LP DR LW++L+ +G++L L+ L+ +
Sbjct: 179 ALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA 238
Query: 1136 VEAISVACAMYEVISMGTSVTGLYPELF----TLLLKLVSCTLGQKMLTCPW--SHRRHV 1189
+ A M V + G YP L T L KL M W SHR
Sbjct: 239 LAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSPDMPKI-WVLSHRG-- 295
Query: 1190 MQQGEQQQIPDPCRLSTATLKCLQAQAMREG--LAKESDEGDNLWTLLSSPSTHHIGVCS 1247
P ++ ++ L+A +G + E W L TH GV
Sbjct: 296 ----------PPHSHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLL 345
Query: 1248 LARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLIL 1307
LA +M + + LL L S+ + R+T AFF+ L++ + LR +IL
Sbjct: 346 LASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTAR--LLREEVIL 403
Query: 1308 MDQSAW--DSNATLRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCES 1365
W D T+R + + GLG+ A + +H +L +++ G +V +
Sbjct: 404 ERLLTWQGDPEPTVRWLGLLGLGHLALN--RRKVRHVSTLLPALL-GALGEGDARLVGAA 460
Query: 1366 LKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIF 1425
L AL+++L L V E+ + +D +D +R +A+ L L ++
Sbjct: 461 LGALRRLL-LRPRAPVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLG 519
Query: 1426 FAEEIKK----SLISFLLHLWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLP 1481
++K SL+ LL L DP+ + L C +G+L+ L+
Sbjct: 520 LRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAF----CWGLLEELVTVAHY 575
Query: 1482 RARDFYRQFCVKLAKKNQEILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVE 1541
+ + C +L ++ + + + + S + +R AA L +V + + V
Sbjct: 576 DSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVN 635
Query: 1542 LLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKETSIP 1584
+ L L L+ DP +V AA + Q + + P
Sbjct: 636 QDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLARARGCP 678
>gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]
Length = 608
Score = 83.2 bits (204), Expect = 2e-15
Identities = 89/384 (23%), Positives = 179/384 (46%), Gaps = 27/384 (7%)
Query: 768 DAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSL--QDH 825
D + F S+ ++ + +++E SL+S +R + + I LS L L +D
Sbjct: 207 DETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDR 266
Query: 826 LNILEENIRRLLPLPPLENLKSEGQTDKDKE-HIQFLYERSMDALGKLLKTMMWDNVNAE 884
+ I+ ++ LP + L + + + + LY ++ A ++L++++ + + E
Sbjct: 267 AELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLE 326
Query: 885 DCQEMFNLLQMWLVSQKEWERERAFQITAKVLT-----NDIEAPENF-KIGSLLGLLAPH 938
+ + L WL S K+ ERERA A+VL +++ P F ++G L+ L+A
Sbjct: 327 NLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALL 386
Query: 939 SCDTLPTIRQAAASSTIGLFYI----KGIHLEVERLQGLQEGLESDDVQVQIKISS---- 990
D + + AA L +I K I + + Q L+ L +++ S+
Sbjct: 387 CGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCF 446
Query: 991 -----KIAKIVSKFIPNEEILMFLEEMLDGLESL-NPTCTKACGIWMITVLKQQGAALED 1044
+IA++ F+ + E+ F+ D L++L +P ++ G ++T+ K + E
Sbjct: 447 YNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFE- 505
Query: 1045 QLLEILGTIYHHMPVLRQKEESFQFILEAISQIAS--FHMDTVVVNLLQKPLPFDRDTKT 1102
++ EI+G I + ++ Q Q I+ +S S + D V+ LL P+P++R
Sbjct: 506 KVPEIMGVICAQLSIISQPRVR-QQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAE 564
Query: 1103 LWKALAEKPASSGKLLQALIDKLE 1126
+W+ L+ + S+ +L L+ KL+
Sbjct: 565 VWRMLSVELPSTTWILWRLLRKLQ 588
>gi|187761379 maestro isoform c [Homo sapiens]
Length = 210
Score = 79.0 bits (193), Expect = 3e-14
Identities = 45/132 (34%), Positives = 75/132 (56%), Gaps = 5/132 (3%)
Query: 1272 TSSSENYRITGAAFFSELMKEPILWK-----HGNLRNVLILMDQSAWDSNATLRQMAIRG 1326
+S E+ +G++ S L + + WK L+NV ++ + A D +A R MA+R
Sbjct: 26 SSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRN 85
Query: 1327 LGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFK 1386
LG A AP KV+K+K+++L+ ++ GLY EV+ ES+K L +L + + + +F
Sbjct: 86 LGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFI 145
Query: 1387 EIVLQTRTFFED 1398
+I LQTRT +D
Sbjct: 146 DITLQTRTLLDD 157
>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
Length = 573
Score = 60.5 bits (145), Expect = 1e-08
Identities = 107/495 (21%), Positives = 202/495 (40%), Gaps = 67/495 (13%)
Query: 795 LDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEGQTDKD 854
LD+ + + +++I S + P L + L I+E + L+ +P L+ +K G + +
Sbjct: 32 LDAYSGLLSNESMILAVNSSFVDPLLQFESQLKIIESSFGMLVVMPSLDKVKEMGSSYEY 91
Query: 855 KEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQM--WLVSQKEWERERAFQIT 912
E ++ LY ++ +L +++ ++D ++ L +M W+ + +ER I
Sbjct: 92 IEDMENLYHNILNIYENILTSLV-----SKDLYKLQILKEMLVWMSKDSSYLQERIMVII 146
Query: 913 AKVLT---------NDIEAPENFKIGSLLGLLAPHSCDTLPTIRQAAASSTIGLFYIKGI 963
KVL ++AP + + L LL H P+I + A+ L YI
Sbjct: 147 NKVLRFTVTKVRKYISVDAPCLGLLAAELSLLCSHED---PSIVKQASLGMCHLLYIARC 203
Query: 964 HLEV---ERLQGLQEGLE--SDDVQVQIK----ISSKIAKIVSKFIPNEEILMFLEEMLD 1014
++ + G L+ S DV+ K SKIA+ V + + + F++ +L
Sbjct: 204 QNDIGTNKPTNGKSHSLQFPSSDVEFLPKEFQQDESKIAQRVGQTLLPPLLTDFVQSLLM 263
Query: 1015 GLESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAI 1074
L S + +I L+ A + +I+ IY L +L+ I
Sbjct: 264 KLSSPDDKIASDAASILIFTLEFH-AEKVTMVSKIVDAIYRQ---LCDNNCMKDVMLQVI 319
Query: 1075 SQIASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLE---TELED 1131
+ + V+ L+ P+P D +WKA + + + +L+ ++ L+ E+ED
Sbjct: 320 TLLTCTSPKKVIFQLMDYPVPADDTLIQMWKAACSQASVAPHVLKTILLILKGKPGEMED 379
Query: 1132 ----------DIARVEAISVACAMYEVISMGT---SVTGLYPELFTLLLKLVSCTLGQKM 1178
DI + ++ A+ + +G+ +V +P+L T L+ V K
Sbjct: 380 TVTEGKRFSLDITNLMPLAACQALCTFLPLGSYRKAVAQYFPQLLTTLMFQVFYNSELK- 438
Query: 1179 LTCPWSHRRHVMQQGEQQQIPDPCRLSTATLKCLQAQAMREGLAKESDEGDNLWTLLSSP 1238
P R + Q D R+ L C Q + L KE N W LS
Sbjct: 439 ---PILKDRALYAQ-------DALRV---LLNCSGLQQVDITLMKE-----NFWDQLSED 480
Query: 1239 STHHIGVCSLARSMA 1253
++ GVC +A++++
Sbjct: 481 LCYYHGVCFIAKTLS 495
>gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]
Length = 573
Score = 57.4 bits (137), Expect = 1e-07
Identities = 78/379 (20%), Positives = 162/379 (42%), Gaps = 52/379 (13%)
Query: 768 DAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSL--QDH 825
D + F S+ ++ + +++E SL+S +R + + I LS L L +D
Sbjct: 207 DETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDR 266
Query: 826 LNILEENIRRLLPLPPLENLKSEGQTDKDKE-HIQFLYERSMDALGKLLKTMMWDNVNAE 884
+ I+ ++ LP + L + + + + LY ++ A ++L++++ + + E
Sbjct: 267 AELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLE 326
Query: 885 DCQEMFNLLQMWLVSQKEWERERAFQITAKVLTNDIEAPENF-KIGSLLGLLAPHSCDTL 943
+ L I+ P F ++G L+ L+A D
Sbjct: 327 N------------------------------LDTIIKLPLRFQRLGHLVALMALLCGDPQ 356
Query: 944 PTIRQAAASSTIGLFYI----KGIHLEVERLQGLQEGLESDDVQVQIKISS--------- 990
+ + AA L +I K I + + Q L+ L +++ S+
Sbjct: 357 EKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPF 416
Query: 991 KIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCT-KACGIWMITVLKQQGAALEDQLLEI 1049
+IA++ F+ + E+ F+ D L++L C ++ G ++T+ K + E ++ EI
Sbjct: 417 RIAQVFEGFLDSNELCQFIMTTFDTLKNLKHPCIQRSAGELLLTLAKNTESQFE-KVPEI 475
Query: 1050 LGTIYHHMPVLRQKEESFQFILEAISQIASF--HMDTVVVNLLQKPLPFDRDTKTLWKAL 1107
+G I + ++ Q Q I+ +S S + D V+ LL P+P++R +W+ L
Sbjct: 476 MGVICAQLSIISQPRVRQQ-IINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRML 534
Query: 1108 AEKPASSGKLLQALIDKLE 1126
+ + S+ +L L+ KL+
Sbjct: 535 SVELPSTTWILWRLLRKLQ 553
>gi|7706457 A-kinase anchor protein 11 [Homo sapiens]
Length = 1901
Score = 36.2 bits (82), Expect = 0.26
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 847 SEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDC--QEMFNLLQMWLVSQKEWE 904
S+G DKD+EH E ++ LG+ KT++ N++ E C ++ WL++ +
Sbjct: 1786 SDGPDDKDEEH-----EDEVEGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEV 1840
Query: 905 RERAFQITAK---VLTNDIEAPENFKIGSLL 932
E F +A +L + + +K+G LL
Sbjct: 1841 AELYFHDSANKEFMLLSKQLQEKGWKVGDLL 1871
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 35.0 bits (79), Expect = 0.58
Identities = 78/359 (21%), Positives = 144/359 (40%), Gaps = 53/359 (14%)
Query: 750 DLQMSFTRSITEIGIAVQDAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIA 809
+LQ SF + +++ E G Q + +E+ I ++ E +D L + K
Sbjct: 1207 ELQKSFETERDHLRGYIREIEATGLQ-TKEELKIAHIHLKEHQETIDELRRSVSEKTAQI 1265
Query: 810 IRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEGQTDKDKEHIQFLYERSMD-- 867
I K LQ+ + +L E + LLP N+K +T + ++ L E+S
Sbjct: 1266 INTQDLEKSHTKLQEEIPVLHEE-QELLP-----NVKEVSETQETMNELELLTEQSTTKD 1319
Query: 868 --ALGKLLKTMMWDNVNAEDCQEMFNLL----------QMWLVSQKEWERERAFQITAKV 915
L ++ + N ++ QE L + L + + +E + AK+
Sbjct: 1320 STTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKI 1379
Query: 916 LTNDIEAPENF----------KIGSLLGLLAPHSCDTLPT-IRQAAASSTIGLFY--IKG 962
+ + ++ KI S + P L I S + + +K
Sbjct: 1380 QESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKS 1439
Query: 963 IHLEVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMF----LEEMLDGLES 1018
+ E + LQ LQE L+S+ Q + I +IV+K + EE L L+E + +
Sbjct: 1440 VAKEKDDLQRLQEVLQSESDQ----LKENIKEIVAKHLETEEELKVAHCCLKEQEETINE 1495
Query: 1019 LNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQI 1077
L ++ I+ +++Q A+ D+L + IY +KEE QF ++ IS++
Sbjct: 1496 LRVNLSEK--ETEISTIQKQLEAINDKLQNKIQEIY-------EKEE--QFNIKQISEV 1543
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 32.7 bits (73), Expect = 2.9
Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 8/88 (9%)
Query: 1264 MEQLLSSLTSSSENYRITGAA-FFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQM 1322
+ LL +TSS +++R + SEL K+ I + R V+ ++ + D N ++ +
Sbjct: 8 ISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNL 67
Query: 1323 AIRGLGNTASGAPHKVKKHKQLMLESII 1350
A++ LG V K K+ +E+I+
Sbjct: 68 AVKCLGPL-------VVKVKEYQVETIV 88
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 32.0 bits (71), Expect = 4.9
Identities = 18/66 (27%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 1264 MEQLLSSLTSSSENYRITGAA-FFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQM 1322
+ LL +TSS +++R + SEL K+ I + R V+ ++ + D N ++ +
Sbjct: 8 ISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNL 67
Query: 1323 AIRGLG 1328
A++ LG
Sbjct: 68 AVKWLG 73
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 32.0 bits (71), Expect = 4.9
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 5/70 (7%)
Query: 1191 QQGEQQQIPDPCRLSTATLKCLQAQAMREGLAK----ESDEGDNLWTLLSSPSTHHIGVC 1246
QQG + + P+PC S +L Q +G A+ E+ GD + L P T ++G C
Sbjct: 225 QQGSECRAPNPCWPSPCSLLA-QCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGC 283
Query: 1247 SLARSMAVWQ 1256
++ V+Q
Sbjct: 284 PSNSTLCVYQ 293
>gi|148612844 ATP-binding cassette, sub-family B, member 5 [Homo
sapiens]
Length = 812
Score = 31.2 bits (69), Expect = 8.3
Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 412 KPVKTNFHENEKEEESVRETSLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLF 471
K +K++F + +E +E SL + L L + P+ WP ++ + + + P+F
Sbjct: 207 KSIKSDFIDKAEESTQSKEISLPEVSLLKILKLNKPE--WPFVVLGTLASVLNGTVHPVF 264
Query: 472 SII 474
SII
Sbjct: 265 SII 267
>gi|4759082 serum deprivation response protein [Homo sapiens]
Length = 425
Score = 31.2 bits (69), Expect = 8.3
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 8/75 (10%)
Query: 319 DEQVRSNNEAIRVGILTLLRLAVN------ADEPRLRDHIISIERTVKIVMGDLS--TKV 370
+E +R N++ V +LTLL VN ++ ++ IS+E +VK + DL+ +K
Sbjct: 44 EEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKY 103
Query: 371 RNSVLLLIQTMCEKS 385
+ S + + EKS
Sbjct: 104 QASTSNTVSKLLEKS 118
>gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6 [Homo
sapiens]
Length = 516
Score = 31.2 bits (69), Expect = 8.3
Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
Query: 1263 IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKH----GNLRNVLILMDQSAWDSNAT 1318
+ +++LS + S++ ++ GA + + H G + ++ L+D+ D N T
Sbjct: 226 VFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVT 285
Query: 1319 LRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGL 1353
++ A+ L N A +K K + E++++ L
Sbjct: 286 VQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFL 320
>gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5 [Homo
sapiens]
Length = 558
Score = 31.2 bits (69), Expect = 8.3
Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
Query: 1263 IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKH----GNLRNVLILMDQSAWDSNAT 1318
+ +++LS + S++ ++ GA + + H G + ++ L+D+ D N T
Sbjct: 268 VFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVT 327
Query: 1319 LRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGL 1353
++ A+ L N A +K K + E++++ L
Sbjct: 328 VQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFL 362
>gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4 [Homo
sapiens]
Length = 559
Score = 31.2 bits (69), Expect = 8.3
Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
Query: 1263 IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKH----GNLRNVLILMDQSAWDSNAT 1318
+ +++LS + S++ ++ GA + + H G + ++ L+D+ D N T
Sbjct: 269 VFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVT 328
Query: 1319 LRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGL 1353
++ A+ L N A +K K + E++++ L
Sbjct: 329 VQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFL 363
>gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3 [Homo
sapiens]
Length = 607
Score = 31.2 bits (69), Expect = 8.3
Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
Query: 1263 IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKH----GNLRNVLILMDQSAWDSNAT 1318
+ +++LS + S++ ++ GA + + H G + ++ L+D+ D N T
Sbjct: 317 VFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVT 376
Query: 1319 LRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGL 1353
++ A+ L N A +K K + E++++ L
Sbjct: 377 VQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFL 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,934,977
Number of Sequences: 37866
Number of extensions: 2266859
Number of successful extensions: 5969
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 5822
Number of HSP's gapped (non-prelim): 54
length of query: 1585
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1469
effective length of database: 13,855,062
effective search space: 20353086078
effective search space used: 20353086078
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.