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Search of human proteins with 153945771
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
(811 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 1653 0.0
gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 1533 0.0
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi... 1475 0.0
gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 1473 0.0
gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapi... 991 0.0
gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapi... 991 0.0
gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] 991 0.0
gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapi... 984 0.0
gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] 548 e-156
gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] 529 e-150
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|90403592 phosphate-regulating neutral endopeptidase [Homo sap... 459 e-129
gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] 359 5e-99
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 37 0.073
gi|169204510 PREDICTED: hypothetical protein [Homo sapiens] 33 1.4
gi|124487387 ring finger protein 207 [Homo sapiens] 33 1.4
gi|239753431 PREDICTED: similar to endothelin converting enzyme-... 32 2.4
gi|169205117 PREDICTED: hypothetical protein [Homo sapiens] 32 2.4
gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo ... 32 2.4
gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo ... 32 2.4
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 31 4.0
gi|110832843 TBP-associated factor 4 [Homo sapiens] 31 4.0
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 31 4.0
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 31 5.3
gi|147903292 nuclear localized factor 1 [Homo sapiens] 31 5.3
gi|91208420 bassoon protein [Homo sapiens] 30 6.9
gi|40353727 synaptopodin isoform A [Homo sapiens] 30 6.9
>gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
Length = 811
Score = 1653 bits (4281), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTP 60
MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTP
Sbjct: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTP 60
Query: 61 GTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALL 120
GTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALL
Sbjct: 61 GTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALL 120
Query: 121 LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL 180
LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL
Sbjct: 121 LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL 180
Query: 181 PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP 240
PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP
Sbjct: 181 PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP 240
Query: 241 LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS 300
LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS
Sbjct: 241 LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS 300
Query: 301 GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV 360
GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV
Sbjct: 301 GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV 360
Query: 361 PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS 420
PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS
Sbjct: 361 PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS 420
Query: 421 ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT 480
ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT
Sbjct: 421 ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT 480
Query: 481 DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA 540
DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA
Sbjct: 481 DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA 540
Query: 541 IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS 600
IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS
Sbjct: 541 IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS 600
Query: 601 MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE 660
MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE
Sbjct: 601 MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE 660
Query: 661 YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY 720
YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY
Sbjct: 661 YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY 720
Query: 721 NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV 780
NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV
Sbjct: 721 NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV 780
Query: 781 LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Sbjct: 781 LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
>gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
Length = 765
Score = 1533 bits (3969), Expect = 0.0
Identities = 765/811 (94%), Positives = 765/811 (94%), Gaps = 46/811 (5%)
Query: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTP 60
MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEV
Sbjct: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEV----------------- 43
Query: 61 GTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALL 120
GFQKGTRQLLGSRTQLELVLAGASLLLAALL
Sbjct: 44 -----------------------------GFQKGTRQLLGSRTQLELVLAGASLLLAALL 74
Query: 121 LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL 180
LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL
Sbjct: 75 LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL 134
Query: 181 PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP 240
PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP
Sbjct: 135 PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP 194
Query: 241 LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS 300
LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS
Sbjct: 195 LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS 254
Query: 301 GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV 360
GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV
Sbjct: 255 GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV 314
Query: 361 PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS 420
PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS
Sbjct: 315 PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS 374
Query: 421 ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT 480
ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT
Sbjct: 375 ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT 434
Query: 481 DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA 540
DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA
Sbjct: 435 DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA 494
Query: 541 IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS 600
IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS
Sbjct: 495 IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS 554
Query: 601 MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE 660
MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE
Sbjct: 555 MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE 614
Query: 661 YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY 720
YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY
Sbjct: 615 YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY 674
Query: 721 NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV 780
NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV
Sbjct: 675 NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV 734
Query: 781 LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Sbjct: 735 LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
sapiens]
Length = 883
Score = 1475 bits (3818), Expect = 0.0
Identities = 726/742 (97%), Positives = 731/742 (98%), Gaps = 2/742 (0%)
Query: 70 WRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGV 129
W V+ + ++ + S VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGV
Sbjct: 144 WTVSSEGVHTVDQVLSE--VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGV 201
Query: 130 QYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNT 189
QYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNT
Sbjct: 202 QYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNT 261
Query: 190 FNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG 249
FNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG
Sbjct: 262 FNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG 321
Query: 250 GWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 309
GWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY
Sbjct: 322 GWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 381
Query: 310 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEE 369
YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEE
Sbjct: 382 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEE 441
Query: 370 KIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPS 429
KIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPS
Sbjct: 442 KIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPS 501
Query: 430 ILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALG 489
ILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALG
Sbjct: 502 ILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALG 561
Query: 490 SLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPD 549
SLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPD
Sbjct: 562 SLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPD 621
Query: 550 FILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY 609
FILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY
Sbjct: 622 FILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY 681
Query: 610 YLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRP 669
YLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRP
Sbjct: 682 YLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRP 741
Query: 670 WWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRK 729
WWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRK
Sbjct: 742 WWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRK 801
Query: 730 HGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRD 789
HGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRD
Sbjct: 802 HGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRD 861
Query: 790 FLRHFGCPVGSPMNPGQLCEVW 811
FLRHFGCPVGSPMNPGQLCEVW
Sbjct: 862 FLRHFGCPVGSPMNPGQLCEVW 883
>gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens]
Length = 736
Score = 1473 bits (3813), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 89 VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRV 148
VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRV
Sbjct: 14 VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRV 73
Query: 149 AGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENT 208
AGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENT
Sbjct: 74 AGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENT 133
Query: 209 TFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKA 268
TFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKA
Sbjct: 134 TFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKA 193
Query: 269 VAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYME 328
VAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYME
Sbjct: 194 VAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYME 253
Query: 329 ELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMD 388
ELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMD
Sbjct: 254 ELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMD 313
Query: 389 WLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLD 448
WLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLD
Sbjct: 314 WLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLD 373
Query: 449 RRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGM 508
RRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGM
Sbjct: 374 RRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGM 433
Query: 509 ISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISE 568
ISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISE
Sbjct: 434 ISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISE 493
Query: 569 DSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPF 628
DSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPF
Sbjct: 494 DSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPF 553
Query: 629 YARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEE 688
YARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEE
Sbjct: 554 YARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEE 613
Query: 689 QYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFF 748
QYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFF
Sbjct: 614 QYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFF 673
Query: 749 VGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLC 808
VGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLC
Sbjct: 674 VGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLC 733
Query: 809 EVW 811
EVW
Sbjct: 734 EVW 736
>gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo
sapiens]
Length = 767
Score = 991 bits (2561), Expect = 0.0
Identities = 480/799 (60%), Positives = 602/799 (75%), Gaps = 47/799 (5%)
Query: 14 MVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSGLFWRVT 73
M YKRATL +ED ++ EG A P+ ++V + PRS W
Sbjct: 15 MSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHS---------------PRSGQRCW--- 56
Query: 74 CPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHR 133
+RTQ+E L +LLAA L+ CL ALG+QY +
Sbjct: 57 --------------------------AARTQVEKRLVVLVVLLAAGLVACLAALGIQY-Q 89
Query: 134 DPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSL 193
S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+ NP+PDG SRW TF++L
Sbjct: 90 TRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNL 149
Query: 194 WDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNI 253
W+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL A+PL +LIE++GGWNI
Sbjct: 150 WEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI 208
Query: 254 TGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 313
TGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+
Sbjct: 209 TGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNK 268
Query: 314 TANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLANITVPQDQRRDEEKIY 372
T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LANIT+PQ++RRDEE IY
Sbjct: 269 TENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIY 328
Query: 373 HKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILN 432
HK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL+Q+S LIN T+ +LN
Sbjct: 329 HKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLN 388
Query: 433 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 492
NY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C+S+T++ LGFALG +F
Sbjct: 389 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 448
Query: 493 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 552
VKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKEKADAIY+MIG+P+FI+
Sbjct: 449 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 508
Query: 553 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLP 612
+PKELD V++ Y D +F+N + +NFS +V ADQLRK P+RDQWSMTP VNAYY P
Sbjct: 509 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSP 568
Query: 613 TKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQ 672
TKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+
Sbjct: 569 TKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWK 628
Query: 673 NESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGE 732
N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGLKAAY AY+ W++K+G
Sbjct: 629 NSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGA 688
Query: 733 EQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLR 792
E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+RFRV+G+LSNS++F
Sbjct: 689 EHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSE 748
Query: 793 HFGCPVGSPMNPGQLCEVW 811
HF CP GSPMNP CEVW
Sbjct: 749 HFRCPPGSPMNPPHKCEVW 767
>gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo
sapiens]
Length = 754
Score = 991 bits (2561), Expect = 0.0
Identities = 480/799 (60%), Positives = 602/799 (75%), Gaps = 47/799 (5%)
Query: 14 MVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSGLFWRVT 73
M YKRATL +ED ++ EG A P+ ++V + PRS W
Sbjct: 2 MSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHS---------------PRSGQRCW--- 43
Query: 74 CPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHR 133
+RTQ+E L +LLAA L+ CL ALG+QY +
Sbjct: 44 --------------------------AARTQVEKRLVVLVVLLAAGLVACLAALGIQY-Q 76
Query: 134 DPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSL 193
S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+ NP+PDG SRW TF++L
Sbjct: 77 TRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNL 136
Query: 194 WDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNI 253
W+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL A+PL +LIE++GGWNI
Sbjct: 137 WEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI 195
Query: 254 TGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 313
TGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+
Sbjct: 196 TGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNK 255
Query: 314 TANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLANITVPQDQRRDEEKIY 372
T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LANIT+PQ++RRDEE IY
Sbjct: 256 TENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIY 315
Query: 373 HKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILN 432
HK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL+Q+S LIN T+ +LN
Sbjct: 316 HKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLN 375
Query: 433 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 492
NY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C+S+T++ LGFALG +F
Sbjct: 376 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 435
Query: 493 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 552
VKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKEKADAIY+MIG+P+FI+
Sbjct: 436 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 495
Query: 553 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLP 612
+PKELD V++ Y D +F+N + +NFS +V ADQLRK P+RDQWSMTP VNAYY P
Sbjct: 496 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSP 555
Query: 613 TKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQ 672
TKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+
Sbjct: 556 TKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWK 615
Query: 673 NESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGE 732
N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGLKAAY AY+ W++K+G
Sbjct: 616 NSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGA 675
Query: 733 EQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLR 792
E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+RFRV+G+LSNS++F
Sbjct: 676 EHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSE 735
Query: 793 HFGCPVGSPMNPGQLCEVW 811
HF CP GSPMNP CEVW
Sbjct: 736 HFRCPPGSPMNPPHKCEVW 754
>gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens]
Length = 770
Score = 991 bits (2561), Expect = 0.0
Identities = 480/799 (60%), Positives = 602/799 (75%), Gaps = 47/799 (5%)
Query: 14 MVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSGLFWRVT 73
M YKRATL +ED ++ EG A P+ ++V + PRS W
Sbjct: 18 MSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHS---------------PRSGQRCW--- 59
Query: 74 CPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHR 133
+RTQ+E L +LLAA L+ CL ALG+QY +
Sbjct: 60 --------------------------AARTQVEKRLVVLVVLLAAGLVACLAALGIQY-Q 92
Query: 134 DPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSL 193
S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+ NP+PDG SRW TF++L
Sbjct: 93 TRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNL 152
Query: 194 WDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNI 253
W+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL A+PL +LIE++GGWNI
Sbjct: 153 WEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI 211
Query: 254 TGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 313
TGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+
Sbjct: 212 TGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNK 271
Query: 314 TANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLANITVPQDQRRDEEKIY 372
T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LANIT+PQ++RRDEE IY
Sbjct: 272 TENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIY 331
Query: 373 HKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILN 432
HK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL+Q+S LIN T+ +LN
Sbjct: 332 HKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 433 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 492
NY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C+S+T++ LGFALG +F
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 493 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 552
VKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKEKADAIY+MIG+P+FI+
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 553 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLP 612
+PKELD V++ Y D +F+N + +NFS +V ADQLRK P+RDQWSMTP VNAYY P
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSP 571
Query: 613 TKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQ 672
TKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+
Sbjct: 572 TKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWK 631
Query: 673 NESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGE 732
N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGLKAAY AY+ W++K+G
Sbjct: 632 NSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGA 691
Query: 733 EQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLR 792
E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+RFRV+G+LSNS++F
Sbjct: 692 EHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSE 751
Query: 793 HFGCPVGSPMNPGQLCEVW 811
HF CP GSPMNP CEVW
Sbjct: 752 HFRCPPGSPMNPPHKCEVW 770
>gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo
sapiens]
Length = 758
Score = 984 bits (2544), Expect = 0.0
Identities = 462/712 (64%), Positives = 577/712 (81%), Gaps = 3/712 (0%)
Query: 101 SRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGV 160
+RTQ+E L +LLAA L+ CL ALG+QY + S S CL+EAC+ V IL S+D V
Sbjct: 49 ARTQVEKRLVVLVVLLAAGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTV 107
Query: 161 SPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKT 220
PC DF+ ++CGGWI+ NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K
Sbjct: 108 DPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKA 166
Query: 221 QRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFT 280
Q +Y +C+ RIEEL A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+
Sbjct: 167 QVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFS 226
Query: 281 VYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTS 340
VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG
Sbjct: 227 VYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEE 286
Query: 341 T-REQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP 399
R QMQQ+L+ E LANIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P
Sbjct: 287 AIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYP 346
Query: 400 LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLL 459
+E+++SEP+VVY +YL+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +
Sbjct: 347 VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM 406
Query: 460 ETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 519
E +YGTKK+C+PRW+ C+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+
Sbjct: 407 EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEES 466
Query: 520 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 579
L L WMDE+TR++AKEKADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +
Sbjct: 467 LSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFF 526
Query: 580 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 639
NFS +V ADQLRK P+RDQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNF
Sbjct: 527 NFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNF 586
Query: 640 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGER 699
GGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE
Sbjct: 587 GGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEP 646
Query: 700 LNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVR 759
+NGR TLGENIADNGGLKAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVR
Sbjct: 647 VNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVR 706
Query: 760 TPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
TPESSHEGL+TDPHSP+RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 707 TPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 758
>gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]
Length = 779
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 109 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 136
L G LLL L+ LVALGV Y R P
Sbjct: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
Query: 137 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 195
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
Query: 196 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 254
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
Query: 255 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 309
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
Query: 310 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 363
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Query: 364 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 419
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
Query: 420 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 479
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
Query: 480 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 539
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
Query: 540 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 597
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
Query: 598 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 657
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
Query: 658 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 714
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
Query: 715 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 774
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
Query: 775 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens]
Length = 775
Score = 529 bits (1362), Expect = e-150
Identities = 267/681 (39%), Positives = 408/681 (59%), Gaps = 20/681 (2%)
Query: 143 EACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK 202
+A R A + +LD + PC+DFY F+CGGW+RR+ +PD + + T ++ +QN+ L+
Sbjct: 103 KAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR 162
Query: 203 HLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGP------ 256
LL A++K + F+ SCL + IE LG +P+ ++IE GGW++ G
Sbjct: 163 RLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGV 222
Query: 257 ---WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 313
WD + +L G Y A F++ +S D ++S+ VI++DQ GL LP R YL +
Sbjct: 223 AARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQ 279
Query: 314 TAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQ--DQRRDEEK 370
+ EK+L AY +ME + LLG + ++ Q++L++E QLANITV + D RRD
Sbjct: 280 DEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQLANITVSEHDDLRRDVSS 337
Query: 371 IYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSI 430
+Y+K+++ +LQ + P + W L + + S+ E VV+ DY+QQVS+LI T +
Sbjct: 338 MYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
Query: 431 LNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGS 490
L+NYL+W +V + L F A +L + + G+ K + C+ + G ALG+
Sbjct: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCLGQANRHFGMALGA 455
Query: 491 LFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDF 550
LFV F SK + ++ +I+ + L +L WMD +TR AA+ K + M+G+PDF
Sbjct: 456 LFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDF 515
Query: 551 ILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYY 610
+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+ + W + PQ +NAYY
Sbjct: 516 LLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
Query: 611 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 670
LP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH +DD G +YD+ GNL W
Sbjct: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
Query: 671 WQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKH 730
W S + F C+ Y+ + V +R+NG+ TLGENIAD GGLK AY+AY+ W+R+H
Sbjct: 635 WTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREH 694
Query: 731 GEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDF 790
G E LP + T+ QLFF+ FAQ WC R +S + ++TD H+P +RVLG++S +F
Sbjct: 695 GPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEF 754
Query: 791 LRHFGCPVGSPMNPGQLCEVW 811
R F CP SPMNP C VW
Sbjct: 755 GRAFHCPKDSPMNPAHKCSVW 775
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 103 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 162
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 163 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 222
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 223 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 276
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 277 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 336
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 337 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 384
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 385 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 442
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 443 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 502
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 503 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 561
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 562 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 621
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 622 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 681
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 682 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 738
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 739 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 798
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 799 GSPMNPGQLCEVW 811
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 103 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 162
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 163 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 222
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 223 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 276
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 277 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 336
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 337 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 384
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 385 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 442
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 443 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 502
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 503 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 561
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 562 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 621
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 622 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 681
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 682 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 738
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 739 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 798
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 799 GSPMNPGQLCEVW 811
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 103 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 162
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 163 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 222
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 223 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 276
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 277 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 336
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 337 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 384
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 385 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 442
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 443 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 502
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 503 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 561
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 562 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 621
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 622 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 681
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 682 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 738
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 739 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 798
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 799 GSPMNPGQLCEVW 811
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 103 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 162
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 163 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 222
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 223 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 276
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 277 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 336
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 337 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 384
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 385 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 442
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 443 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 502
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 503 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 561
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 562 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 621
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 622 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 681
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 682 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 738
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 739 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 798
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 799 GSPMNPGQLCEVW 811
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|90403592 phosphate-regulating neutral endopeptidase [Homo
sapiens]
Length = 749
Score = 459 bits (1182), Expect = e-129
Identities = 262/746 (35%), Positives = 407/746 (54%), Gaps = 32/746 (4%)
Query: 92 QKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGK 151
+ G + G+R L +V G +L+L +L LV+ G+ CL CI A
Sbjct: 10 ETGKKANRGTRIAL-VVFVGGTLVLGTILF--LVSQGL-LSLQAKQEYCLKPECIEAAAA 65
Query: 152 ILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENT-TF 210
IL ++ V PC++F++F+C GWI NP+P+ + + L LK LLE + +
Sbjct: 66 ILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISR 125
Query: 211 NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG-GWNIT-------GPWDQDNF 262
+EA QK + Y SC+ + IE+ A+PL ++ W + G W + F
Sbjct: 126 RRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKF 185
Query: 263 --MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYL-NRTANEKV 319
++ L G Y + F +Y+S D K+SN +++++DQ+ L L R+ YL N T +
Sbjct: 186 SLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSY 245
Query: 320 LTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISE 379
A +M + +LLG + M+ VL LEI++A I +P + R E +Y+KM+ISE
Sbjct: 246 RDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEA-MYNKMNISE 304
Query: 380 LQALAPSMDWLEFLSFLLSPL------ELSDSEPVVVYGMDYLQQVSELINRTEPSILNN 433
L A+ P DWL ++ ++ ++S SE VVV Y + + ++ + N
Sbjct: 305 LSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIAN 364
Query: 434 YLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFV 493
YL+W +V +L RRF+ + + GT + +P+W C++ + AL + +G +FV
Sbjct: 365 YLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTT-TLLPQWDKCVNFIESALPYVVGKMFV 423
Query: 494 KATFDRQSKEIAEGMISEIRTAFEEALG-QLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 552
F KE+ E ++ +R AF + L + WMD T++ AKEKA A+ +G+P+FI+
Sbjct: 424 DVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIM 483
Query: 553 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLP 612
+++ + SE +F N+L + A+ LRK + +W P TVNA+Y
Sbjct: 484 NDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSA 543
Query: 613 TKNEIVFPAGILQAPFY-ARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWW 671
+ N+I FPAG LQ PF+ +P++L++G IGV++GHE TH FD+ GR+YDK GNL PWW
Sbjct: 544 STNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWW 603
Query: 672 QNESLAAFRNHTACMEEQYNQY--QVNGERLNGRQTLGENIADNGGLKAAYNAYKAWL-- 727
ES F+ T CM QY+ Y + G + G++TLGENIADNGGL+ A+ AY+ W+
Sbjct: 604 STESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWIND 663
Query: 728 RKHG-EEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSN 786
R+ G EE LP + TN+QLFF+ +A V C+ PE++ E + HSP +FRV G +SN
Sbjct: 664 RRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISN 723
Query: 787 SRDFLRHFGCPVGSPMNPG-QLCEVW 811
+F + F CP S MN G C +W
Sbjct: 724 FEEFQKAFNCPPNSTMNRGMDSCRLW 749
>gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens]
Length = 732
Score = 359 bits (922), Expect = 5e-99
Identities = 224/718 (31%), Positives = 355/718 (49%), Gaps = 53/718 (7%)
Query: 114 LLLAALLLGCLVALGVQYH---RDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFS 170
+L A L+LG L+ V ++ C T C+ + L S + V+PC DF+ F+
Sbjct: 48 VLTAILILGLLLCFSVLLFYNFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFA 107
Query: 171 CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQV 230
CG N N+F L +N+ L+ +LE E+K +FY SC+
Sbjct: 108 CGRAKETN---------NSFQELATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDT 158
Query: 231 ERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSS 290
IE G PLR +IE++GGW I+G W NF L+ + Y PFF Y+ S
Sbjct: 159 LAIEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASP 218
Query: 291 NSNVIQVDQSGLFLPSRDYYLNRTANEK----VLTAYLDYMEELGMLLGGRPTSTREQMQ 346
++ VIQ+DQ P D L + +K + YL Y+ +LG LLGG P+ +E
Sbjct: 219 HTPVIQIDQ-----PEFDVPLKQDQEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSS 273
Query: 347 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 406
+ + +L P +QRR + K++ ++I +L+ +AP++DWL L +P+ LS S+
Sbjct: 274 LSISITSRLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQ 333
Query: 407 PVVVYGMDYLQQVSELINR---TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLY 463
+VV+ ++YL+ +S+L+ + L +++I LV + +LD +F+ A+ KL + L
Sbjct: 334 SLVVHDVEYLKNMSQLVEEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLR 393
Query: 464 GTKKS----CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 519
+ PRW C+ T L +LFV+ F ++ A + + IR A
Sbjct: 394 ELTEQPPMPARPRWMKCVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITR 453
Query: 520 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 579
L L WM+E+T+ A++K + +G ++ L+P+ Y+ ++ SF Q++L+
Sbjct: 454 LRNLPWMNEETQNMAQDKVAQLQVEMGASEWALKPELARQEYNDIQLG-SSFLQSVLSCV 512
Query: 580 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 639
+ +P + +W ++P VNAYY + + +VFPAG+LQ PF+ +P+A+NF
Sbjct: 513 RSLRARIVQSFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNF 572
Query: 640 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHT-----ACMEEQYNQYQ 694
G G +M HEL H F L P A NH C++ Y +
Sbjct: 573 GAAGSIMAHELLHIFYQL---------LLP----GGCLACDNHALQEAHLCLKRHYAAFP 619
Query: 695 V-NGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQ 753
+ + N T EN AD GGL A AY L +H E LP++ L+ Q+FF +AQ
Sbjct: 620 LPSRTSFNDSLTFLENAADVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQ 679
Query: 754 VWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
V C +P+ SH D HSP RV G LS++ F R+F C G+ +NP C++W
Sbjct: 680 VMCRKPSPQDSH-----DTHSPPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW 732
>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
Length = 1159
Score = 37.0 bits (84), Expect = 0.073
Identities = 36/135 (26%), Positives = 51/135 (37%), Gaps = 30/135 (22%)
Query: 28 PETPVEGGASPDAME--VGKGASPFSPGPSPGMTP-----GTPRSSGLFWRVTCPHLRSI 80
P +P G A P E +G P +PGPSPG P G P + W P +
Sbjct: 68 PRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERAAP----L 123
Query: 81 SGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTC 140
+G+ SR V + L G T + ++ + +L+ L YH D
Sbjct: 124 AGVASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILI-----LTKYYHAD------ 172
Query: 141 LTEACIRVAGKILES 155
GK+LES
Sbjct: 173 --------MGKVLES 179
>gi|169204510 PREDICTED: hypothetical protein [Homo sapiens]
Length = 257
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 30 TPVEGGASPDAMEVGKGAS-PFSPGPSPGMTPGTPRSSG 67
+P G A P A E+G+G P +PGPSP P + ++G
Sbjct: 198 SPRRGAAGPGACELGEGRRLPRAPGPSPPPLPASADAAG 236
>gi|124487387 ring finger protein 207 [Homo sapiens]
Length = 634
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 509 ISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIG-FPDFILEPKE--LDDVYDGYE 565
+ ++TA EA+ L M E+ R +A E+ DAI+ + G D + E K L V YE
Sbjct: 211 VKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYE 270
Query: 566 ISEDSFFQNMLNL 578
+ +F + + +L
Sbjct: 271 EKDKAFKEQLSHL 283
>gi|239753431 PREDICTED: similar to endothelin converting
enzyme-like 1 [Homo sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.4
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 428 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 487
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 488 LGSLFV 493
L +LFV
Sbjct: 72 LRALFV 77
>gi|169205117 PREDICTED: hypothetical protein [Homo sapiens]
Length = 257
Score = 32.0 bits (71), Expect = 2.4
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 30 TPVEGGASPDAMEVGKGAS-PFSPGPSPGMTPGTPRSSG 67
+P G A P A E+G+G P +PGPSP P + ++G
Sbjct: 198 SPRGGAAGPGACELGEGRRLPRAPGPSPPPLPASADAAG 236
>gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo
sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.4
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 428 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 487
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 488 LGSLFV 493
L +LFV
Sbjct: 72 LRALFV 77
>gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo
sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.4
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 428 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 487
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 488 LGSLFV 493
L +LFV
Sbjct: 72 LRALFV 77
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/58 (41%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Query: 30 TPVEGGASPDAMEVGKGASPFSPGPSPGM--TPGTPRSSGLFWRVTCPHLRSISGLCS 85
TP G SP A AS FSPG SP TPG+P S G + P++ S G S
Sbjct: 1540 TPGAAGFSPSA---ASDASGFSPGYSPAWSPTPGSPGSPG----PSSPYIPSPGGAMS 1590
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 31.2 bits (69), Expect = 4.0
Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 2/44 (4%)
Query: 25 EDAPETPVE-GGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSG 67
E AP P + G + A G G P PGP PG PG P G
Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGP-GPGPGPGPGPGKPAGPG 193
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 31.2 bits (69), Expect = 4.0
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 708 ENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFV 749
+++A+N G YN Y A L + Q+LP L NH L+ +
Sbjct: 27 QSLAENSGTTVVYNPYAA-LSIEQQRQKLPVFKLRNHILYLI 67
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related
ADP-ribose polymerase [Homo sapiens]
Length = 1327
Score = 30.8 bits (68), Expect = 5.3
Identities = 12/20 (60%), Positives = 15/20 (75%)
Query: 49 PFSPGPSPGMTPGTPRSSGL 68
P SPG +PG TP +P +SGL
Sbjct: 34 PLSPGLAPGTTPASPTASGL 53
>gi|147903292 nuclear localized factor 1 [Homo sapiens]
Length = 369
Score = 30.8 bits (68), Expect = 5.3
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 4/58 (6%)
Query: 34 GGASPDAMEVGKGASPFSPGPSPGMTPGTPR--SSGLFWRVT-CPHLRSISGLCSRTM 88
GG PDA+ +G P +PGP+ PG PR L R C LR GL SR +
Sbjct: 137 GGGGPDAL-LGTLRVPRAPGPATPAAPGCPRPPQDALARRPRGCRLLRVPDGLLSRAL 193
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 30.4 bits (67), Expect = 6.9
Identities = 15/34 (44%), Positives = 15/34 (44%)
Query: 28 PETPVEGGASPDAMEVGKGASPFSPGPSPGMTPG 61
P P GG P A A P PGP PG PG
Sbjct: 37 PSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG 70
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 30.4 bits (67), Expect = 6.9
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 28 PETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTP 63
P + ++G SP E G+G+S SP P P P +P
Sbjct: 695 PPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSP 730
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,388,449
Number of Sequences: 37866
Number of extensions: 1543271
Number of successful extensions: 5211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5067
Number of HSP's gapped (non-prelim): 82
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.