Search of human proteins with 153945715

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153945715 myosin VC [Homo sapiens]
         (1742 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153945715 myosin VC [Homo sapiens]                                3441   0.0  
gi|215982794 myosin VA isoform 2 [Homo sapiens]                      1795   0.0  
gi|215982791 myosin VA isoform 1 [Homo sapiens]                      1787   0.0  
gi|122937345 myosin VB [Homo sapiens]                                1646   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...   611   e-174
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...   611   e-174
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...   608   e-173
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...   608   e-173
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...   608   e-173
gi|156104908 myosin heavy chain 6 [Homo sapiens]                      608   e-173
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...   608   e-173
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   607   e-173
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   607   e-173
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...   606   e-173
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   604   e-172
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   604   e-172
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...   595   e-170
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...   595   e-169
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]              590   e-168
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    588   e-167
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   587   e-167
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     554   e-157
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     554   e-157
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     554   e-157
gi|122937512 myosin VIIB [Homo sapiens]                               552   e-157
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]          550   e-156
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]          549   e-156
gi|154354979 myosin X [Homo sapiens]                                  548   e-155
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]          546   e-155
gi|118402590 myosin XV [Homo sapiens]                                 500   e-141

>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 3441 bits (8922), Expect = 0.0
 Identities = 1742/1742 (100%), Positives = 1742/1742 (100%)

Query: 1    MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPL 60
            MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPL
Sbjct: 1    MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPL 60

Query: 61   RNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDA 120
            RNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDA
Sbjct: 61   RNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDA 120

Query: 121  IIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFAT 180
            IIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFAT
Sbjct: 121  IIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFAT 180

Query: 181  VSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTY 240
            VSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTY
Sbjct: 181  VSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTY 240

Query: 241  LLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDR 300
            LLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDR
Sbjct: 241  LLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDR 300

Query: 301  AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360
            AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE
Sbjct: 301  AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360

Query: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
            LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA
Sbjct: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420

Query: 421  LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480
            LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI
Sbjct: 421  LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480

Query: 481  PWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR 540
            PWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR
Sbjct: 481  PWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR 540

Query: 541  MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF 600
            MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF
Sbjct: 541  MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF 600

Query: 601  GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE 660
            GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE
Sbjct: 601  GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE 660

Query: 661  FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVV 720
            FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVV
Sbjct: 661  FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVV 720

Query: 721  LHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRER 780
            LHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRER
Sbjct: 721  LHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRER 780

Query: 781  RAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAY 840
            RAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAY
Sbjct: 781  RAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAY 840

Query: 841  SRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLED 900
            SRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLED
Sbjct: 841  SRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLED 900

Query: 901  QNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAK 960
            QNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAK
Sbjct: 901  QNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAK 960

Query: 961  LQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQ 1020
            LQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQ
Sbjct: 961  LQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQ 1020

Query: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
            DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080

Query: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
            LQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFA
Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFA 1140

Query: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
            YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE
Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200

Query: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
            VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260

Query: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
            RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320

Query: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLIL 1380
            EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLIL
Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLIL 1380

Query: 1381 DLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEM 1440
            DLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEM
Sbjct: 1381 DLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEM 1440

Query: 1441 LSFWLSNTCHFLNCLKQYSGEEEFMKHNSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQF 1500
            LSFWLSNTCHFLNCLKQYSGEEEFMKHNSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQF
Sbjct: 1441 LSFWLSNTCHFLNCLKQYSGEEEFMKHNSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQF 1500

Query: 1501 IIIMEKNIQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDDTDGYTMTSVLQQLSYFYT 1560
            IIIMEKNIQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDDTDGYTMTSVLQQLSYFYT
Sbjct: 1501 IIIMEKNIQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDDTDGYTMTSVLQQLSYFYT 1560

Query: 1561 TMCQNGLDPELVRQAVKQLFFLIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDK 1620
            TMCQNGLDPELVRQAVKQLFFLIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDK
Sbjct: 1561 TMCQNGLDPELVRQAVKQLFFLIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDK 1620

Query: 1621 NLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFE 1680
            NLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFE
Sbjct: 1621 NLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFE 1680

Query: 1681 KRVTPSFVRKVQALLNSREDSSQLMLDTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLN 1740
            KRVTPSFVRKVQALLNSREDSSQLMLDTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLN
Sbjct: 1681 KRVTPSFVRKVQALLNSREDSSQLMLDTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLN 1740

Query: 1741 RL 1742
            RL
Sbjct: 1741 RL 1742


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 1795 bits (4650), Expect = 0.0
 Identities = 964/1875 (51%), Positives = 1289/1875 (68%), Gaps = 180/1875 (9%)

Query: 1    MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPES--LP 58
            MA +ELYT++ RVWIPDPEEVWKSAE+ KDY+ GDKVL L LE+G +L+Y ++P++  LP
Sbjct: 1    MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60

Query: 59   PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118
             LRNPDILVGENDLTALSYLHEPAVLHNLR+RF +SKLIYTY GI+LVA+NPY+QLPIYG
Sbjct: 61   HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120

Query: 119  DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178
            + II+AYSGQNMGDMDPHIFAVAEEAYKQMAR+ RNQSIIVSGESGAGKTVSA+YAMRYF
Sbjct: 121  EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180

Query: 179  ATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
            ATVS S S A+VE+KVLASNPI E++GNAKTTRNDNSSRFGKY EI FD++ +IIGANM 
Sbjct: 181  ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240

Query: 239  TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
            TYLLEKSRVVFQ+E ERNYHIFYQLCASA+  EFK L+LG+A+ FNYT+ GG+ VIEGV+
Sbjct: 241  TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300

Query: 299  DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVF 358
            D  EM  T++  TLLG  E  QM +F+ILA ILHLGNV  T+   +  ++      L +F
Sbjct: 301  DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360

Query: 359  CELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERIN 418
            C+L+G++   +  WLC+RK+ T++ET +KP+++ QA NARDALAK IYA LF++IV+ +N
Sbjct: 361  CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420

Query: 419  QALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 478
            QAL  + KQH+FIGVLDIYGFETF++NSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE
Sbjct: 421  QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480

Query: 479  DIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEK 538
             IPWTLIDFYDNQP I+LIE+K+GIL+LLDEEC +P GTD+ W QKLYN  +N+  LFEK
Sbjct: 481  QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540

Query: 539  PRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPS 598
            PR+SN +F+IQHFADKVEY+CEGFLEKN+DTV++  +++L++SKF +    FQ++    S
Sbjct: 541  PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600

Query: 599  PFGSMITVKS--AKQVIKPN-------SKHFRTTVGSKFRSSLYLLMETLNATTPHYVRC 649
            P  +  + ++   +   KP        +K  + TVG +FR+SL+LLMETLNATTPHYVRC
Sbjct: 601  PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660

Query: 650  IKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELS 709
            IKPND K PF FD KR VQQLRACGVLETIRISA  +PSRWTY EF+SRY +LM KQ+  
Sbjct: 661  IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM-KQKDV 719

Query: 710  FSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRG 769
             SD+K+ CK VL +LI D ++YQFGKTKIFFRAGQVAYLEKLR DKLR +C+ +QK +RG
Sbjct: 720  LSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRG 779

Query: 770  WLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQL 829
            WL RKK+LR R+AA+ +Q+Y RG Q       A  L+   AA IIQK+ R Y+VR  Y++
Sbjct: 780  WLLRKKYLRMRKAAITMQRYVRGYQA---RCYAKFLRRTKAATIIQKYWRMYVVRRRYKI 836

Query: 830  IRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRF-------------- 875
             R ATI +Q+Y RGFLAR RYRK+L EHKAVI+QK  R WLAR  +              
Sbjct: 837  RRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCF 896

Query: 876  ----------------QSIRRF-VLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAAL 918
                            +S+ R+  L+I +  ++ +LQ+K+++QNK+   LVEKLT+L  +
Sbjct: 897  RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956

Query: 919  RAGDVEK----------------------------IQKLEAELEKAATHRRNYEEKGKRY 950
               + EK                            I KL  +LE+  + ++  EE   RY
Sbjct: 957  YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRY 1016

Query: 951  RDAVEEKLAKLQKHNSELETQKEQIQLKL----QEKTEELKEKMDNLTKQLFDDVQKEER 1006
            +   E+ ++ L++ N+ L+ +KE +  ++    +E TE +++K+   TKQL  D+  E  
Sbjct: 1017 KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE-- 1074

Query: 1007 QRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDG---------- 1056
                      L+ Q+   +   L+E    LK+E   + H+ +  H  +D           
Sbjct: 1075 ---------RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125

Query: 1057 LKAEVARLSK-QVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLE 1112
              +E+A +     +T    EK++ L  +  + ++K V   + +K+ M++++    +Q+L 
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR 1185

Query: 1113 SYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFK 1172
            S   E+ R ++   +LE           YE LK+                 +E+E+ N K
Sbjct: 1186 SKAKEEERPQIRGAELE-----------YESLKR-----------------QELESENKK 1217

Query: 1173 VVHLSQEINHLQKLFREENDIN------ESIRHEVTRLTSENMMIPDFKQQI----SELE 1222
               L  E+N L+K   E++          + R  + +LTS +  +   K+++    S+L 
Sbjct: 1218 ---LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLV 1274

Query: 1223 KQKQDLEIR-----------LNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIH 1271
             QK+ ++ +           L E  +KMK K  E++      +E        L++Q   H
Sbjct: 1275 SQKEAIQPKDDKNTMTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRLLESQLQSQKRSH 1333

Query: 1272 TKEKEKLIDKIQEMQEASDHLKK------QFETESEVKCNFRQEASRLTLENRDLEEELD 1325
              E E L  +IQ ++E ++  ++      Q   E+ ++ + + E +RLT EN DL E+L+
Sbjct: 1334 ENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLE 1393

Query: 1326 MKDRVIKKLQDQVKTLSKTIGK------------------ANDVHSSSGPKEYLGMLQYK 1367
             +D+ ++KL+ Q+K  +K IG+                     V+     K++ GML+YK
Sbjct: 1394 KQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYK 1453

Query: 1368 REDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSTINGI 1427
            +EDE KL++NLIL+LKPRGV VN+IPGLPA+ILFMCVR+AD LND   ++SL+ STIN I
Sbjct: 1454 KEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSI 1513

Query: 1428 KQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGEEEFMKHNSPQQNKNCLNNFDLSEYRQ 1487
            K+V+K+  +DFE +SFWLSNTC FL+CLKQYSGEE FMKHN+ +QN++CL NFDL+EYRQ
Sbjct: 1514 KKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQ 1573

Query: 1488 ILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDDTDGYT 1547
            +LSD+AI+IY Q + ++E  +QP+IV GMLE+E++QG+SG+KPTG RKR+SSI D   YT
Sbjct: 1574 VLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYT 1633

Query: 1548 MTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFFLIGAVTLNSLFLRKDMCSCRKGMQIR 1607
            + S+L+QL+ F++ MCQ+G+DPEL++Q VKQ+F++IGA+TLN+L LRKDMCS  KGMQIR
Sbjct: 1634 LDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIR 1693

Query: 1608 CNISYLEEWLKDKNLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQII 1667
             N+S LEEWL+DKNL NS AKETLEPL QAA LLQVKK TD DA+ I   C +L+  QI+
Sbjct: 1694 YNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIV 1753

Query: 1668 KILNSYTPIDDFEKRVTPSFVRKVQALLNSREDSSQLMLDTKYLFQVTFPFTPSPHALEM 1727
            K+LN YTP+++FE+RV+ SF+R +Q  L  R+DS QL++D K++F VTFPF PS  ALE 
Sbjct: 1754 KVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALET 1813

Query: 1728 IQIPSSFKLGFLNRL 1742
            IQIP+S  LGF++R+
Sbjct: 1814 IQIPASLGLGFISRV 1828


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 1787 bits (4629), Expect = 0.0
 Identities = 968/1901 (50%), Positives = 1295/1901 (68%), Gaps = 205/1901 (10%)

Query: 1    MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPES--LP 58
            MA +ELYT++ RVWIPDPEEVWKSAE+ KDY+ GDKVL L LE+G +L+Y ++P++  LP
Sbjct: 1    MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60

Query: 59   PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118
             LRNPDILVGENDLTALSYLHEPAVLHNLR+RF +SKLIYTY GI+LVA+NPY+QLPIYG
Sbjct: 61   HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120

Query: 119  DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178
            + II+AYSGQNMGDMDPHIFAVAEEAYKQMAR+ RNQSIIVSGESGAGKTVSA+YAMRYF
Sbjct: 121  EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180

Query: 179  ATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
            ATVS S S A+VE+KVLASNPI E++GNAKTTRNDNSSRFGKY EI FD++ +IIGANM 
Sbjct: 181  ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240

Query: 239  TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
            TYLLEKSRVVFQ+E ERNYHIFYQLCASA+  EFK L+LG+A+ FNYT+ GG+ VIEGV+
Sbjct: 241  TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300

Query: 299  DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVF 358
            D  EM  T++  TLLG  E  QM +F+ILA ILHLGNV  T+   +  ++      L +F
Sbjct: 301  DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360

Query: 359  CELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERIN 418
            C+L+G++   +  WLC+RK+ T++ET +KP+++ QA NARDALAK IYA LF++IV+ +N
Sbjct: 361  CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420

Query: 419  QALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 478
            QAL  + KQH+FIGVLDIYGFETF++NSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE
Sbjct: 421  QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480

Query: 479  DIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEK 538
             IPWTLIDFYDNQP I+LIE+K+GIL+LLDEEC +P GTD+ W QKLYN  +N+  LFEK
Sbjct: 481  QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540

Query: 539  PRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPS 598
            PR+SN +F+IQHFADKVEY+CEGFLEKN+DTV++  +++L++SKF +    FQ++    S
Sbjct: 541  PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600

Query: 599  PFGSMITVKS--AKQVIKPN-------SKHFRTTVGSKFRSSLYLLMETLNATTPHYVRC 649
            P  +  + ++   +   KP        +K  + TVG +FR+SL+LLMETLNATTPHYVRC
Sbjct: 601  PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660

Query: 650  IKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELS 709
            IKPND K PF FD KR VQQLRACGVLETIRISA  +PSRWTY EF+SRY +LM KQ+  
Sbjct: 661  IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM-KQKDV 719

Query: 710  FSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRG 769
             SD+K+ CK VL +LI D ++YQFGKTKIFFRAGQVAYLEKLR DKLR +C+ +QK +RG
Sbjct: 720  LSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRG 779

Query: 770  WLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQL 829
            WL RKK+LR R+AA+ +Q+Y RG Q       A  L+   AA IIQK+ R Y+VR  Y++
Sbjct: 780  WLLRKKYLRMRKAAITMQRYVRGYQA---RCYAKFLRRTKAATIIQKYWRMYVVRRRYKI 836

Query: 830  IRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRF-------------- 875
             R ATI +Q+Y RGFLAR RYRK+L EHKAVI+QK  R WLAR  +              
Sbjct: 837  RRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCF 896

Query: 876  ----------------QSIRRF-VLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAAL 918
                            +S+ R+  L+I +  ++ +LQ+K+++QNK+   LVEKLT+L  +
Sbjct: 897  RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956

Query: 919  RAGDVEK----------------------------IQKLEAELEKAATHRRNYEEKGKRY 950
               + EK                            I KL  +LE+  + ++  EE   RY
Sbjct: 957  YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRY 1016

Query: 951  RDAVEEKLAKLQKHNSELETQKEQIQLKL----QEKTEELKEKMDNLTKQLFDDVQKEER 1006
            +   E+ ++ L++ N+ L+ +KE +  ++    +E TE +++K+   TKQL  D+  E  
Sbjct: 1017 KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE-- 1074

Query: 1007 QRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDG---------- 1056
                      L+ Q+   +   L+E    LK+E   + H+ +  H  +D           
Sbjct: 1075 ---------RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125

Query: 1057 LKAEVARLSK-QVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLE 1112
              +E+A +     +T    EK++ L  +  + ++K V   + +K+ M++++    +Q+L 
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR 1185

Query: 1113 SYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFK 1172
            S   E+ R ++   +LE           YE LK+                 +E+E+ N K
Sbjct: 1186 SKAKEEERPQIRGAELE-----------YESLKR-----------------QELESENKK 1217

Query: 1173 VVHLSQEINHLQKLFREENDIN------ESIRHEVTRLTSENMMIPDFKQQI----SELE 1222
               L  E+N L+K   E++          + R  + +LTS +  +   K+++    S+L 
Sbjct: 1218 ---LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLV 1274

Query: 1223 KQKQDLEIR-----------LNEQAEKMKGK---------LEELSN----QLHRSQEE-- 1256
             QK+ ++ +           L E  +KMK K         L+E +       H   E+  
Sbjct: 1275 SQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGE 1334

Query: 1257 -----EGTQR------KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKK------QFETE 1299
                 EG ++        L++Q   H  E E L  +IQ ++E ++  ++      Q   E
Sbjct: 1335 LWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPE 1394

Query: 1300 SEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGK------------ 1347
            + ++ + + E +RLT EN DL E+L+ +D+ ++KL+ Q+K  +K IG+            
Sbjct: 1395 ARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPG 1454

Query: 1348 ------ANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILF 1401
                     V+     K++ GML+YK+EDE KL++NLIL+LKPRGV VN+IPGLPA+ILF
Sbjct: 1455 QIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILF 1514

Query: 1402 MCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGE 1461
            MCVR+AD LND   ++SL+ STIN IK+V+K+  +DFE +SFWLSNTC FL+CLKQYSGE
Sbjct: 1515 MCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGE 1574

Query: 1462 EEFMKHNSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYES 1521
            E FMKHN+ +QN++CL NFDL+EYRQ+LSD+AI+IY Q + ++E  +QP+IV GMLE+E+
Sbjct: 1575 EGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHET 1634

Query: 1522 LQGISGLKPTGFRKRSSSIDDTDGYTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFF 1581
            +QG+SG+KPTG RKR+SSI D   YT+ S+L+QL+ F++ MCQ+G+DPEL++Q VKQ+F+
Sbjct: 1635 IQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFY 1694

Query: 1582 LIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDKNLQNSLAKETLEPLSQAAWLL 1641
            +IGA+TLN+L LRKDMCS  KGMQIR N+S LEEWL+DKNL NS AKETLEPL QAA LL
Sbjct: 1695 IIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLL 1754

Query: 1642 QVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFEKRVTPSFVRKVQALLNSREDS 1701
            QVKK TD DA+ I   C +L+  QI+K+LN YTP+++FE+RV+ SF+R +Q  L  R+DS
Sbjct: 1755 QVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDS 1814

Query: 1702 SQLMLDTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLNRL 1742
             QL++D K++F VTFPF PS  ALE IQIP+S  LGF++R+
Sbjct: 1815 PQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 1855


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 1646 bits (4263), Expect = 0.0
 Identities = 922/1896 (48%), Positives = 1240/1896 (65%), Gaps = 202/1896 (10%)

Query: 1    MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPE--SLP 58
            M+V ELY+Q  RVWIPDP+EVW+SAE+ KDY+ GDK L+L LED T L+Y ++ +   LP
Sbjct: 1    MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60

Query: 59   PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118
             LRNPDILVGENDLTALSYLHEPAVLHNL++RF ES  IYTY GI+LVA+NPY+QLPIYG
Sbjct: 61   FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120

Query: 119  DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178
              +I+ YSGQNMGDMDPHIFAVAEEAYKQMAR+ +NQSIIVSGESGAGKTVSA+YAMRYF
Sbjct: 121  QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180

Query: 179  ATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
            ATV  S S  ++E+KVLAS+PI EA+GNAKTTRNDNSSRFGKY +I FD++  IIGANM 
Sbjct: 181  ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240

Query: 239  TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
            TYLLEKSRVVFQ+++ERNYHIFYQLCA+A   EFK L L SAE+F YT  GG+T IEGV+
Sbjct: 241  TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300

Query: 299  DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERS-SVSEDDSHLKV 357
            D  +  +T++ FTLLG KE  QM +FKI+A+ILHLG+V I A  +  S S+S  D +L  
Sbjct: 301  DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360

Query: 358  FCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERI 417
            FC LLG+E  ++  WLC+RK+VT+SET VK M+  Q +NAR+ALAK IYA LF +IVE I
Sbjct: 361  FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420

Query: 418  NQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 477
            N+AL  S KQH+FIGVLDIYGFETF+VNSFEQFCINYANEKLQQQFN HVFKLEQEEYMK
Sbjct: 421  NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480

Query: 478  EDIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFE 537
            E IPWTLIDFYDNQP IDLIEAK+GIL+LLDEEC +P GTD+NW QKLY+   + +  F+
Sbjct: 481  EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQ 539

Query: 538  KPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENP--- 594
            KPRMSNT+F+I HFADKVEY  +GFLEKNRDTVY+  + IL+ASKF L A+ F ++    
Sbjct: 540  KPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPV 599

Query: 595  ---TPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIK 651
               TP     S I+V+SA+  +K ++K  + TVG +FR+SL+LLMETLNATTPHYVRCIK
Sbjct: 600  PATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIK 659

Query: 652  PNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFS 711
            PNDEKLPF FD KR VQQLRACGVLETIRISA  YPSRW Y +F++RY +L+ K+EL+ +
Sbjct: 660  PNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANT 719

Query: 712  DKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWL 771
            DKK +C+ VL  LI+D +++QFG+TKIFFRAGQVAYLEKLR DK R + +M+QK +RGWL
Sbjct: 720  DKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWL 779

Query: 772  QRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIR 831
            Q+ K+ R + A L +Q+Y RG    R    A  L+   AA+++QKH R    R  YQ +R
Sbjct: 780  QKVKYHRLKGATLTLQRYCRGHLARR---LAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836

Query: 832  MATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR- 890
             A + +QA++R    RR YR++L EHKA  +QK+ R W+ARR FQ +R   + IQ  +R 
Sbjct: 837  RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896

Query: 891  ------------------------------VQRLQKKLEDQNKENHGLVEKLTSLAALRA 920
                                          V +LQ+K+++QNKE   L E+L+   +   
Sbjct: 897  LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956

Query: 921  GDVEKIQK-----------------------LEAELEKAATHRRNYEEKGKRYRDAVEEK 957
             +VE+++K                       L  EL++A + R+  E+   R +D + ++
Sbjct: 957  MEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKR 1016

Query: 958  LAKLQKHNSELETQKEQI--QLKLQEKTEELKEKM-DNLTKQLFDDVQKEERQRMLLEKS 1014
            +A L++ N+ L+ +KEQ+  Q+  Q K E  +  + +NL K+  +    EER R      
Sbjct: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELE----EERSRY----- 1067

Query: 1015 FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEF 1074
                 Q+  K+   L++    L+DE   ++         S+    E       + T    
Sbjct: 1068 -----QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIG 1122

Query: 1075 EKEIELLQAQKIDVEK---------HVQSQKREMREKMSEITKQL--LESYDIEDVRSRL 1123
            + E  L Q ++I +EK          +Q + RE+ ++  ++  QL   E  D + V++  
Sbjct: 1123 DTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEP 1182

Query: 1124 SVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHL 1183
               D++ L+ + +L  AY  LK+                 +E+E+ N K   L  ++N L
Sbjct: 1183 PQTDID-LDPNADL--AYNSLKR-----------------QELESENKK---LKNDLNEL 1219

Query: 1184 QKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIR----LNEQAEKM 1239
            +K   ++   N S         S ++++   K    ELE +K+++ I     ++    ++
Sbjct: 1220 RKAVADQATQNNSSHGSPD---SYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRL 1276

Query: 1240 KGKLEELS---------NQLHRSQEE-------------------------------EGT 1259
             G+  E +         ++ H  QE+                               +G 
Sbjct: 1277 AGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGL 1336

Query: 1260 QRKA------LEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQF------ETESEVKCNFR 1307
            ++ A      L+AQ+  H +E E L  +++ ++E  D  ++ F        E++V+   +
Sbjct: 1337 KQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQ 1396

Query: 1308 QEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSG----------- 1356
            QE SRLT EN DL+E ++  ++  +KL+ Q+K   K   KA D+ ++             
Sbjct: 1397 QEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMK---KAQDLEAAQALAQSERKRHEL 1453

Query: 1357 ---------PKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYA 1407
                      K++ GML+Y +EDEA LI+NL+ DLKP+ ++   +P LPA+IL+MC+R+A
Sbjct: 1454 NRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQ-MLSGTVPCLPAYILYMCIRHA 1512

Query: 1408 DSLNDANMLKSLMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGEEEFMKH 1467
            D  ND   + SL+ STINGIK+V+K+H +DFEM SFWLSNTC  L+CLKQYSG+E FM  
Sbjct: 1513 DYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQ 1572

Query: 1468 NSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYESLQGISG 1527
            N+ +QN++CL NFDL+EYRQ+LSD++I+IY Q I I E  +QP+IV  MLE ES+QG+SG
Sbjct: 1573 NTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSAMLENESIQGLSG 1632

Query: 1528 LKPTGFRKRSSSIDDTDG-YTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFFLIGAV 1586
            +KPTG+RKRSSS+ D D  Y + ++++Q++ F+T MC  GLDPE++ Q  KQLF++I AV
Sbjct: 1633 VKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAV 1692

Query: 1587 TLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDKNLQNSLAKETLEPLSQAAWLLQVKKT 1646
            TLN+L LRKD+CS   GMQ+R NIS LEEWL+ +NL  S A +T+EPL QAA LLQ+KK 
Sbjct: 1693 TLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKK 1752

Query: 1647 TDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFEKRVTPSFVRKVQALLNSREDSSQLML 1706
            T  DA+ I   CTSLS  QI+KILN YTP+++FE+RVT +F+R +QA L  R D  QL+L
Sbjct: 1753 TQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQLQERNDPQQLLL 1812

Query: 1707 DTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLNRL 1742
            D K++F V FPF PS   ++ I IP+   L FLN +
Sbjct: 1813 DAKHMFPVLFPFNPSSLTMDSIHIPACLNLEFLNEV 1848


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score =  611 bits (1576), Expect = e-174
 Identities = 441/1431 (30%), Positives = 723/1431 (50%), Gaps = 94/1431 (6%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVN-PESLPPLRNPDILVGEND 71
            V++PD ++ +  A+I    R G KV        TE   +V   E     +NP       D
Sbjct: 37   VFVPDDKQEFVKAKIVS--REGGKVTA-----ETEYGKTVTVKEDQVMQQNPPKFDKIED 89

Query: 72   LTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMG 131
            +  L++LHEPAVL+NL+ R+  S +IYTYSG+  V +NPYK LP+Y   ++ AY G+   
Sbjct: 90   MAMLTFLHEPAVLYNLKDRYG-SWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRS 148

Query: 132  DMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH-- 189
            +  PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFA ++  G  +   
Sbjct: 149  EAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKD 208

Query: 190  -------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLL 242
                   +ED+++ +NP  EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYLL
Sbjct: 209  QSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLL 268

Query: 243  EKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRA 301
            EKSRV+FQ + ER+YHIFYQ+ ++ ++ E   + L +   ++Y  +  G T +  ++D  
Sbjct: 269  EKSRVIFQLKAERDYHIFYQILSN-KKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327

Query: 302  EMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCEL 361
            E++ T   F +LGF  + +  ++K+  AI+H GN++      E  +  +          L
Sbjct: 328  ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387

Query: 362  LGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL 421
            +GL S  + + LC+ ++   +E V K     Q + A  ALAK +Y  +F+++V RIN  L
Sbjct: 388  MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447

Query: 422  QFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIP 481
            +    +  FIGVLDI GFE FD NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I 
Sbjct: 448  ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 507

Query: 482  WTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR 540
            WT IDF  D Q  IDLIE  MGI+ +L+EEC+ P  TD  +  KL++N + ++  F+KPR
Sbjct: 508  WTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPR 567

Query: 541  ----MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTP 596
                     F + H+A  V+Y   G+L+KN+D + + +V + + S   L +  F      
Sbjct: 568  NIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGA 627

Query: 597  PSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEK 656
             +P      ++  K   K  S     TV +  R +L  LM  L +T PH+VRCI PN+ K
Sbjct: 628  DAP------IEKGKGKAKKGSSF--QTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETK 679

Query: 657  LPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MTKQELSFSDKK 714
             P   D+  ++ QLR  GVLE IRI  + +P+R  Y +F  RY IL      E  F D +
Sbjct: 680  SPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSR 739

Query: 715  EVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR- 773
            +  + +L  L  D NQY+FG TK+FF+AG +  LE++R ++L +    +Q   RG L R 
Sbjct: 740  KGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARM 799

Query: 774  --KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIR 831
              KK L  R + L+IQ   R    V K    + L      ++        +     +  R
Sbjct: 800  EYKKLLERRDSLLVIQWNIRAFMGV-KNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858

Query: 832  MATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLN-IQLTYR 890
            +     ++ +R      +   +L+E   + LQ  A         +   + + N IQL  +
Sbjct: 859  LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAK 918

Query: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY 950
            V+ + ++LED+ + N  L  K   L    +     I  LE  L K    +   E K K  
Sbjct: 919  VKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978

Query: 951  RD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTK------QLFDDV 1001
             +    ++E +AKL K    L+   +Q    LQ +    ++K++ LTK      Q  DD+
Sbjct: 979  TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE----EDKVNTLTKAKVKLEQQVDDL 1034

Query: 1002 QKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEV 1061
            +    Q   +    E   +  E  ++  +E I  L+++K QL   ++ +    + L A +
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094

Query: 1062 -------ARLSKQVK----TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL 1110
                   ++L K++K     I E E+E+E  +  +  VEK     + ++  ++ EI+++L
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK----LRSDLSRELEEISERL 1150

Query: 1111 LESYDIEDVRSRLSVE----------DLEHLNEDGELWFAYEGLKKATRVLE-----SHF 1155
             E+     V+  ++ +          DLE      E   A    K A  V E      + 
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210

Query: 1156 QSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFK 1215
            Q  K   EK  E   FK + L    ++++++ + + ++ +  R    ++        + +
Sbjct: 1211 QRVKQKLEK--EKSEFK-LELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQ 1267

Query: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
            + +++L  Q+  L+    E + ++  K E L +QL R +     Q + L+ Q E   K K
Sbjct: 1268 RSVNDLTSQRAKLQTENGELSRQLDEK-EALISQLTRGKLTYTQQLEDLKRQLEEEVKAK 1326

Query: 1276 EKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEELDMKDRVIKK 1333
              L   +Q  +   D L++Q+E E+E K   ++  S+   E      + E D   R  ++
Sbjct: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT-EE 1385

Query: 1334 LQDQVKTLSKTIGKAND-VHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
            L++  K L++ + +A + V + +     L   +++ ++E   I++L++D++
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE---IEDLMVDVE 1433



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 110/520 (21%), Positives = 222/520 (42%), Gaps = 63/520 (12%)

Query: 848  RRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHG 907
            ++ R+ LEE  A +  +   A L ++   S+      I     +QR+++KLE +  E   
Sbjct: 1172 QKMRRDLEE--ATLQHEATAAALRKKHADSVAELGEQID---NLQRVKQKLEKEKSEFKL 1226

Query: 908  LVEKLTSLAALRAGDVEKIQKLEAELEKAAT--------HRRNYEEKGKRYRDAVEEKLA 959
             ++ +TS       ++E+I K +A LEK           HR   EE  +   D   ++ A
Sbjct: 1227 ELDDVTS-------NMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR-A 1278

Query: 960  KLQKHNSELETQKEQIQLKLQEKTE---ELKEKMDNLTKQLFDDVQKEERQRMLLEKS-- 1014
            KLQ  N EL  Q ++ +  + + T       +++++L +QL ++V+ +      L+ +  
Sbjct: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338

Query: 1015 -FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQV-KTIS 1072
              +L  + YE++ ++  E  + L     ++          +     E+    K++ + + 
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398

Query: 1073 EFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLN 1132
            E E+ +E + A+   +EK     + E+ + M ++ +    +  ++  +        E   
Sbjct: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458

Query: 1133 EDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREEND 1192
            +  E     E  +K  R L +     K+ YE+ +E              HL+   RE  +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE--------------HLETFKRENKN 1504

Query: 1193 INESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR 1252
            + E I     +L S    I + ++   +LE +K +L+  L E    +             
Sbjct: 1505 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASL------------- 1551

Query: 1253 SQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS-DHLK--KQFETESEVKCNFRQE 1309
             + EEG   +A    N+I  + + KL +K +EM++A  +HL+     +T  + +   R E
Sbjct: 1552 -EHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNE 1610

Query: 1310 ASRLTL----ENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
            A R+      +  ++E +L   +R+  + Q QVK+L   +
Sbjct: 1611 ALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL 1650



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 106/534 (19%), Positives = 235/534 (44%), Gaps = 63/534 (11%)

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
            T +++ L+++LE++ K  + L   L S      L     E+  + +AEL++         
Sbjct: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1368

Query: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
            A  R  YE    +  + +EE   KL +   E E   E +  K     E+ K ++ N  + 
Sbjct: 1369 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS-LEKTKHRLQNEIED 1427

Query: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
            L  DV++       L+K           ++ K ++ + +++S ++E ++L  E  +L++ 
Sbjct: 1428 LMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNA 1487

Query: 1047 VEG--EHVTS-----DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
             E   EH+ +       L+ E++ L++Q+    KTI E EK  + L+A+K++++  ++  
Sbjct: 1488 YEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEA 1547

Query: 1096 KREMREKMSEITKQLLESYDIE-DVRSRLSVEDLE-------HLNEDGELWFAYEG-LKK 1146
            +  +  +  +I +  LE   I+ ++  +L+ +D E       HL     L  + +   + 
Sbjct: 1548 EASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRS 1607

Query: 1147 ATRVLESHFQSQKDCYEKEIEA--LNFKVVHLSQEINHLQKLFREEN-DINESIRHEVTR 1203
                L    + + D  E EI+    N       +++  LQ L ++    +++++R     
Sbjct: 1608 RNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN--- 1664

Query: 1204 LTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR 1261
                     D K+ I+ +E++   L+  L    E+++  +E+       +++E  E ++R
Sbjct: 1665 --------DDLKENIAIVERRNNLLQAEL----EELRAVVEQTERSRKLAEQELIETSER 1712

Query: 1262 -KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
             + L +QN     +K+K+   + ++Q   +   ++     E       +A+ +  E +  
Sbjct: 1713 VQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE 1772

Query: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
            ++     +R+ K ++  +K L   + +A  +    G K+   +    RE E +L
Sbjct: 1773 QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL 1826



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 97/503 (19%), Positives = 209/503 (41%), Gaps = 41/503 (8%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    +  +    +++  +S+   +  ++  Y  +   + LE   +EN 
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENK 1503

Query: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
             L E+++ L        + I +LE   ++    +   +   +    ++E +  K+ +   
Sbjct: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563

Query: 967  ELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKTQ 1020
            E    K +I+ KL EK EE+++   N   +   L   +  E R R   + ++K  E    
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623

Query: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK-TISEFEKEIE 1079
            + E Q+          + +   LQ L++   +  D    +  R +  +K  I+  E+   
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD----DAVRANDDLKENIAIVERRNN 1679

Query: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITK-----QLLESYDIEDVRSRLSVE-DLEHLNE 1133
            LLQA+  ++   V+  +R  +    E+ +     QLL S +   +  +  ++ DL  L  
Sbjct: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQT 1739

Query: 1134 DGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEIN-HLQKLFREEND 1192
            + E     E +++     E   ++  D       A+  + +   Q+ + HL+++ +    
Sbjct: 1740 EVE-----EAVQECRNAEEKAKKAITDA------AMMAEELKKEQDTSAHLERMKKNMEQ 1788

Query: 1193 INESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR 1252
              + ++H +    +E + +   K+Q+ +LE + ++LE   NE   + K   E +     +
Sbjct: 1789 TIKDLQHRLDE--AEQIALKGGKKQLQKLEARVRELE---NELEAEQKRNAESV-----K 1838

Query: 1253 SQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASR 1312
               +   + K L  Q E   K   +L D + ++Q      K+Q E   E       +  +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898

Query: 1313 LTLENRDLEEELDMKDRVIKKLQ 1335
            +  E  + EE  D+ +  + KL+
Sbjct: 1899 VQHELDEAEERADIAESQVNKLR 1921



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 45/198 (22%), Positives = 96/198 (48%), Gaps = 21/198 (10%)

Query: 891  VQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKAATHRRNYEEKG 947
            + +LQ ++E+  +E     EK       AA+ A +++K Q   A LE+    ++N E+  
Sbjct: 1734 LSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM---KKNMEQTI 1790

Query: 948  KRYRDAVEE-----------KLAKLQKHNSELETQKEQIQLKLQEKTEELKE---KMDNL 993
            K  +  ++E           +L KL+    ELE + E  Q +  E  + +++   ++  L
Sbjct: 1791 KDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKEL 1850

Query: 994  TKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVT 1053
            T Q  +D +   R + L++K  +LK + Y++Q +  +E+      +  ++QH ++     
Sbjct: 1851 TYQTEEDRKNLLRLQDLVDK-LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEER 1909

Query: 1054 SDGLKAEVARLSKQVKTI 1071
            +D  +++V +L  + + I
Sbjct: 1910 ADIAESQVNKLRAKSRDI 1927


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score =  611 bits (1575), Expect = e-174
 Identities = 437/1383 (31%), Positives = 694/1383 (50%), Gaps = 120/1383 (8%)

Query: 12   RVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNP--DILVGE 69
            RVW+PD ++ +  AE+  +   G    R+ +E   +    V    L P+  P  D+L   
Sbjct: 76   RVWVPDEQDAYVEAEVKSEATGG----RVTVETKDQKVLMVREAELQPMNPPRFDLL--- 128

Query: 70   NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129
             D+  +++L+E +VLHNLR R+A   +IYTYSG+  V +NPYK LP+Y  +++ AY G+ 
Sbjct: 129  EDMAMMTHLNEASVLHNLRQRYARW-MIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKR 187

Query: 130  MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG---- 185
              D  PHI+AVA+ AY  M RN  NQS++++GESGAGKTV+ +  ++YFA V+  G    
Sbjct: 188  RSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPG 247

Query: 186  ---------SNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGAN 236
                     +   +ED+++ +NP  EA GNAKT RNDNSSRFGK+  I F    ++  A+
Sbjct: 248  KKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASAD 307

Query: 237  MSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIE 295
            + +YLLEKSRV+FQ   ER+YH++YQ+  S ++ E + + L S   ++Y     G   ++
Sbjct: 308  IDSYLLEKSRVIFQLPGERSYHVYYQIL-SGRKPELQDMLLLSMNPYDYHFCSQGVITVD 366

Query: 296  GVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHL 355
             +ND  E++ T     +LGF  D +   +KI+ A+LH GN++      E  + ++     
Sbjct: 367  NMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESA 426

Query: 356  KVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVE 415
                 L+G+ SG + + L + ++   +E V K  +  Q V A  ALAK  Y  LF ++V 
Sbjct: 427  DKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVS 486

Query: 416  RINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEY 475
            RINQ L     +  FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY
Sbjct: 487  RINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEY 546

Query: 476  MKEDIPWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNP 534
             +E I W  IDF  D QP IDLIE  +GIL +L+EEC+ P  +D ++  KLY+N   ++P
Sbjct: 547  KREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSP 606

Query: 535  LFEKPRMS-----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANF 589
             F++PR          F + H+A  V Y   G+LEKN+D + + +V I + S+  L A  
Sbjct: 607  NFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATL 666

Query: 590  FQENPTPPSPFGSMITVKSAKQVIKPNSKHFRT--TVGSKFRSSLYLLMETLNATTPHYV 647
            ++        +    + +  K  +K   K   +  TV    + +L  LM  L AT PH+V
Sbjct: 667  YEN-------YAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFV 719

Query: 648  RCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK-- 705
            RCI PN+ K P   D+  ++ QLR  GVLE IRI  Q +P+R  Y +F  RY IL     
Sbjct: 720  RCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAI 779

Query: 706  QELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQK 765
             + +F D ++  + +L  L  D  QYQFG TK+FF+AG +  LE+LR  +L +   ++Q 
Sbjct: 780  PDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQA 839

Query: 766  HMRGWLQR---KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYL 822
              RG L R   ++ L  R A   IQ   R    V+          +W  +  +      L
Sbjct: 840  RSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVK--------NWSWMKLFFKMK---PL 888

Query: 823  VRSLYQLIRMATITMQAYS-RGFL--ARRRYRKMLEEHKAVILQKYARAWLARRRFQSI- 878
            +RS      +A +  +    RG L  A  + +++ E H ++  +K   A   +    ++ 
Sbjct: 889  LRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLA 948

Query: 879  ----RRFVL---NIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEA 931
                R  +L    +QL  +V+ L ++LED+ + N  L  +   L        + I  L+ 
Sbjct: 949  DAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKL 1008

Query: 932  ELEKAATHRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQ-------------- 974
             L KA   ++  E K K   +   A++E +A+L K    L+   +Q              
Sbjct: 1009 TLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSA 1068

Query: 975  ---IQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQ---DYEKQIQS 1028
                +L+L+++ E+L+  ++   K   D     ER +  LE   +L  +   D  +  Q 
Sbjct: 1069 LTKAKLRLEQQVEDLECSLEQEKKLRMD----TERAKRKLEGDLKLTQESVADAAQDKQQ 1124

Query: 1029 LKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDV 1088
            L+E++K    E  QL   VE E +    ++ ++  L  + +   E E+E+E  +A +  V
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAE---ELEEELEAERAARARV 1181

Query: 1089 EKHVQSQKREMREKMSEITKQLLESYDI-----EDVRSRLSV-----EDLEHLNEDGELW 1138
            EK    Q+ E   ++ E++++L E+        E  R R +       +LE      E  
Sbjct: 1182 EK----QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEAT 1237

Query: 1139 FAYEGLKKATRVLE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDI 1193
             A    K+A    E        Q  +   EKE   L  +V  L+  +   + L R +   
Sbjct: 1238 VAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV---ETLTRAKASA 1294

Query: 1194 NESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRS 1253
             +  R    +L+   + + + ++Q+++   Q+  L+    E +  ++ K E L +QL R 
Sbjct: 1295 EKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEK-ECLISQLSRG 1353

Query: 1254 QEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRL 1313
            +       + L  Q E  +K K  L   +Q ++   D L++Q E E+E +   ++  S+ 
Sbjct: 1354 KALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKA 1413

Query: 1314 TLE 1316
              E
Sbjct: 1414 NAE 1416



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 127/558 (22%), Positives = 247/558 (44%), Gaps = 55/558 (9%)

Query: 852  KMLEEHKAVILQKYARAWLARRRFQSIRRFV-----LNIQLTYRVQRLQ------KKLED 900
            ++LEE + +I Q      LA +  + +RR +         L + VQ L+      ++  +
Sbjct: 1338 RLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHE 1397

Query: 901  QNKENHGLVEKLTSLAALRAG------DVEKIQKLEAELEKAATHRRNYEEKGKRYRDAV 954
            +  E    +++L S A           + + IQ+ E ELE+A        ++ +   +A 
Sbjct: 1398 EEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTE-ELEEAKKKLALRLQEAEEGVEAA 1456

Query: 955  EEKLAKLQKHNSELETQKEQIQLKLQEKTEE---LKEKMDNLTKQLFDDVQKEERQRMLL 1011
              K + L+K    L+T+ E + L+L+  T     L +K  +L + L      EER+R   
Sbjct: 1457 NAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERAL------EERRRQEE 1510

Query: 1012 EKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQV--- 1068
            E   EL+    +++ + L  E+  L+    +    +E     +  L+ E++ L+ QV   
Sbjct: 1511 EMQRELEAA--QRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLS 1568

Query: 1069 -KTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIE-DVRSRLSVE 1126
             K+I E EK  + L+ +K +++  ++  +  +  + ++  +  LE   ++ +V  +L+ +
Sbjct: 1569 GKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEK 1628

Query: 1127 DLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKL 1186
            D E  N       A E L+ A+   E+  +++    +K++E     +  L  ++ H    
Sbjct: 1629 DEECANLRRNHQRAVESLQ-ASLDAETRARNEALRLKKKMEG---DLNDLELQLGHAT-- 1682

Query: 1187 FREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIR---LNEQAEKMKGKL 1243
             R+  +   + R    +L  E     + ++  +EL +Q Q LE R   L  + E+++  L
Sbjct: 1683 -RQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAAL 1741

Query: 1244 E--ELSNQLHRSQEEEGTQR-KALEAQNEIHTKEKEKL-IDKIQEMQEASDHLKKQFETE 1299
            E  E S +L   +  E T+R   L +QN     +K+KL  D  Q   E  +  +++ E E
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1801

Query: 1300 SEVKCNFRQEASRLTLENRDLEEELDMK---DRVIKKLQDQVKTLSKTIGKANDVHSSSG 1356
             + K      A    +   +L++E D     +R+ K L+  V+ L   + +A       G
Sbjct: 1802 EKAKKAITDAA----MMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGG 1857

Query: 1357 PKEYLGMLQYKREDEAKL 1374
             K+   +    RE EA+L
Sbjct: 1858 KKQVQKLEAKVRELEAEL 1875



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 108/490 (22%), Positives = 197/490 (40%), Gaps = 67/490 (13%)

Query: 892  QRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYR 951
            + +Q++LE   +E+ GL    T L  LR G  E ++ LE          +N +E+     
Sbjct: 1510 EEMQRELEAAQRESRGLG---TELFRLRHGHEEALEALET----LKRENKNLQEEISDLT 1562

Query: 952  DAVE---EKLAKLQKHNSELETQKEQ---------------------IQLKLQEKTEELK 987
            D V    + + +L+K    LE +K +                     IQL+L +   E+ 
Sbjct: 1563 DQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVD 1622

Query: 988  EKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLV 1047
             K+    ++  +  +  +R    L+ S + +T+   + ++  K+    L D ++QL    
Sbjct: 1623 RKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQL---- 1678

Query: 1048 EGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEIT 1107
               H T    +A+ A    Q +     E++    + Q++  E H Q+Q  E R  +    
Sbjct: 1679 --GHATRQATEAQAATRLMQAQL---KEEQAGRDEEQRLAAELHEQAQALERRASLLAAE 1733

Query: 1108 KQLLESYDIEDVRSRLSVED--LEHLNEDGELWFAYEGLKKATRVLESHF---------- 1155
             + L +   +  RSR   E   LE       L     GL    + LE+            
Sbjct: 1734 LEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEA 1793

Query: 1156 -QSQKDCYEKEIEALN---FKVVHLSQEINHLQKLFREENDINESIRHEVTRL-TSENMM 1210
             Q +++  EK  +A+         L +E +    L R +  + +++R    RL  +E   
Sbjct: 1794 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 1853

Query: 1211 IPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEI 1270
            +   K+Q+ +LE + ++LE  L+ + +K    L+ +     R +E        L  Q E 
Sbjct: 1854 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKE--------LAYQAEE 1905

Query: 1271 HTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTL-ENRDLEEELDMKDR 1329
              K   ++ D + ++Q      K+QFE E+E + N      R    E  D EE  DM + 
Sbjct: 1906 DRKNLARMQDLVDKLQSKVKSYKRQFE-EAEQQANTNLAKYRKAQHELDDAEERADMAET 1964

Query: 1330 VIKKLQDQVK 1339
               KL+ + +
Sbjct: 1965 QANKLRARTR 1974



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 120/605 (19%), Positives = 244/605 (40%), Gaps = 140/605 (23%)

Query: 828  QLIRMATITMQAYSRGFLARRRYRKMLEEHKAVI-LQKYARAWLARRRFQSIRRFVLNIQ 886
            +L ++ T+ +QA SRG L R  Y+++L    A+  +Q   RA+ A + +  ++ F     
Sbjct: 829  RLAKVLTL-LQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLF----- 882

Query: 887  LTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK 946
              ++++ L +  + + +           LAALRA    +++ L   L             
Sbjct: 883  --FKMKPLLRSAQAEEE-----------LAALRA----ELRGLRGALA------------ 913

Query: 947  GKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEER 1006
                  A E K  +L++ +  +  +K  + L+LQ + + L +               EER
Sbjct: 914  ------AAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADA--------------EER 953

Query: 1007 QRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSK 1066
              +L++   +L+ +        +KE  + L+DE          E V +D      AR  K
Sbjct: 954  CHLLIKSKVQLEGK--------VKELSERLEDE----------EEVNAD----LAARRRK 991

Query: 1067 QVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE 1126
                 +E +K+I+ L+      EK    +K+    K+  +T+++     +++  +RL+ E
Sbjct: 992  LEDECTELKKDIDDLKLTLAKAEK----EKQATENKVKNLTEEMAA---LDESVARLTKE 1044

Query: 1127 DLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKE--IEALNFKVVHLSQEINHLQ 1184
                              KKA +  E+H Q+  D   +E  + AL    + L Q++  L+
Sbjct: 1045 ------------------KKALQ--EAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLE 1084

Query: 1185 KLFREENDINESIRHEVTRLTSENMMIPDF-------KQQISELEKQK----QDLEIRLN 1233
                +E  +         +L  +  +  +        KQQ+ E  K+K      L +R+ 
Sbjct: 1085 CSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVE 1144

Query: 1234 EQ---AEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASD 1290
            ++     +M+ K++EL  +    +EE       LEA+     + +++  +  +E++E S+
Sbjct: 1145 DEQLLGAQMQKKIKELQARAEELEEE-------LEAERAARARVEKQRAEAARELEELSE 1197

Query: 1291 HLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKAND 1350
             L++     +  +   R+  + L    R+LEE     +  +  L+ +    +  +G    
Sbjct: 1198 RLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELG---- 1253

Query: 1351 VHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSL 1410
                    E +  LQ  R+   K    L +++      V  +    A    +C  Y D L
Sbjct: 1254 --------EQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 1305

Query: 1411 NDANM 1415
            ++A +
Sbjct: 1306 SEAKI 1310


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  608 bits (1569), Expect = e-173
 Identities = 454/1440 (31%), Positives = 718/1440 (49%), Gaps = 107/1440 (7%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            V++ +P+E +    I    R G KV  +  E G  L  +V  + + P+ NP       D+
Sbjct: 38   VFVAEPKESFVKGTIQS--REGGKVT-VKTEGGATL--TVKDDQVFPM-NPPKYDKIEDM 91

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              +++LHEPAVL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   +
Sbjct: 92   AMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQE 150

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189
              PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G       
Sbjct: 151  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEI 210

Query: 190  --------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYL 241
                    +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYL
Sbjct: 211  TSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270

Query: 242  LEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDR 300
            LEKSRVVFQ + ER+YHIFYQ+  S ++ E   + L +   ++Y  +  G   +  ++D+
Sbjct: 271  LEKSRVVFQLKAERSYHIFYQI-TSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329

Query: 301  AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360
             E++ T     +LGF  + ++ ++K+  A++H GN++      E  +  +          
Sbjct: 330  EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389

Query: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
            L  L S  + + LC  ++   +E V K  T  Q  NA  ALAK +Y  +F ++V RINQ 
Sbjct: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449

Query: 421  LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480
            L     +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 450  LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509

Query: 481  PWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
             WT IDF  D    I+LIE  MGI  +L+EEC+ P  TD ++  KLY+  + ++  F+KP
Sbjct: 510  EWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569

Query: 540  RM----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595
            ++    +   F + H+A  V+Y   G+LEKN+D + + +V + + S     A  F    T
Sbjct: 570  KVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQT 629

Query: 596  PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
                         AK+  K     F+ TV + FR +L  LM  L +T PH+VRCI PN+ 
Sbjct: 630  AEGEGAG----GGAKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684

Query: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713
            K P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E  F D 
Sbjct: 685  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744

Query: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
            K+  + +L  +  D  QY+FG TK+FF+AG +  LE++R DKL Q     Q   RG+L R
Sbjct: 745  KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804

Query: 774  KKFLR--ERRAALIIQQY-FRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830
             ++ R  ERR A+   QY  R    V+           W  +  +      L++S     
Sbjct: 805  VEYQRMVERREAIFCIQYNIRSFMNVK--------HWPWMKLFFKIK---PLLKSAETEK 853

Query: 831  RMATI--TMQAYSRGFLARRRYRKMLEEHKAVI--------LQKYARA-WLARRRFQSIR 879
             MAT+    Q            RK LEE    +        LQ  A A  LA    +  +
Sbjct: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913

Query: 880  RFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATH 939
                 IQL  +++ + ++ ED+ + N  L  K   L    +   + I  LE  L K    
Sbjct: 914  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973

Query: 940  RRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKM 990
            +   E K K   +    ++E +AKL K    L+   +Q    LQ + +++      K K+
Sbjct: 974  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033

Query: 991  DNLTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEK 1040
            +     L   +++E++ RM LE          K  +    D E + Q L E++K  + E 
Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093

Query: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100
              LQ  +E E      L+ ++  L  +   I E E+EIE  +A +   EK    Q+ ++ 
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QRSDLS 1146

Query: 1101 EKMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKKATRV 1150
             ++ EI+++L E     S  IE  + R +       DLE      E   A    K A  V
Sbjct: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1206

Query: 1151 LE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLT 1205
             E      + Q  K   EKE   +  ++  L+  +  + K       +  ++  +++ L 
Sbjct: 1207 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266

Query: 1206 SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALE 1265
            S+     + ++ I++L  Q+  L+    E + ++  K E L +QL R ++    Q + L+
Sbjct: 1267 SKE---EEQQRLINDLTAQRGRLQTESGEFSRQLDEK-EALVSQLSRGKQAFTQQIEELK 1322

Query: 1266 AQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEE 1323
             Q E   K K  L   +Q  +   D L++Q+E E E K   ++  S+   E      + E
Sbjct: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382

Query: 1324 LDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
             D   R  ++L++  K L++ +  A +   +   K     L+  ++     +++L+LD++
Sbjct: 1383 TDAIQRT-EELEEAKKKLAQRLQAAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMLDVE 1439



 Score = 77.8 bits (190), Expect = 9e-14
 Identities = 99/525 (18%), Positives = 222/525 (42%), Gaps = 45/525 (8%)

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
            T +++ L+++LE++ K  + L   L S      L     E+ Q+ +AEL++A        
Sbjct: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEV 1374

Query: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
            A  R  YE    +  + +EE   KL +     E   E +  K     E+ K+++ N  + 
Sbjct: 1375 AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCAS-LEKTKQRLQNEVED 1433

Query: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
            L  DV++       L+K           ++ K ++   ++++ ++E ++L  E  ++++ 
Sbjct: 1434 LMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNA 1493

Query: 1047 VEGEHVTSDGLKAEVARLSKQV-----------KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
             E      + LK E   L +++           K I E EK  + ++ +K +++  ++  
Sbjct: 1494 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1553

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +  +  +  +I +  LE   ++    R   E  E +++            ++T  L++  
Sbjct: 1554 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQST--LDAEI 1611

Query: 1156 QSQKDCY--EKEIEA-LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIP 1212
            +S+ D    +K++E  LN   + L+       +  R   +    ++     L        
Sbjct: 1612 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE 1671

Query: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNE 1269
            D K+Q++ +E++   L+  +    E+++  LE+       +++E  + ++R + L  QN 
Sbjct: 1672 DLKEQLAMVERRANLLQAEI----EELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727

Query: 1270 IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329
                 K+KL   I +MQ   + + ++     E       +A+ +  E +  ++     +R
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787

Query: 1330 VIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
            + K ++  VK L   + +A  +    G K+   +    RE E ++
Sbjct: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1832



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 97/511 (18%), Positives = 216/511 (42%), Gaps = 57/511 (11%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    + +A    +++  +S+   +  I+  Y  +    +LE   +EN 
Sbjct: 1452 QRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAY--EESLDQLETLKRENK 1509

Query: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
             L ++++ L    A   ++I +LE   ++    +   +   +    ++E +  K+ +   
Sbjct: 1510 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQL 1569

Query: 967  ELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKTQ 1020
            EL   K ++  K+ EK EE+ +   N   + + +   +  E R R   + L+K  E    
Sbjct: 1570 ELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1629

Query: 1021 DYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069
            + E Q+           ++ +     LKD ++ L   +  +    + LK ++A + ++  
Sbjct: 1630 EMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQ----EDLKEQLAMVERRAN 1685

Query: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128
             +   + EIE L+A     E+  +  ++E+ +    +  QLL + +   + ++  +E D+
Sbjct: 1686 LL---QAEIEELRATLEQTERSRKIAEQELLDASERV--QLLHTQNTSLINTKKKLETDI 1740

Query: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQK 1185
              +  +                +E   Q  ++  EK  +A+    +    L +E +    
Sbjct: 1741 SQMQGE----------------MEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784

Query: 1186 LFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244
            L R + ++ ++++    RL  +E + +   K+QI +LE + ++LE  +  + ++    ++
Sbjct: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK 1844

Query: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304
             L     R +E        L  Q E   K   +L D + ++Q      K+Q E   E   
Sbjct: 1845 GLRKHERRVKE--------LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 1305 NFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335
                +  +L  E  + EE  D+ +  + KL+
Sbjct: 1897 TNLAKFRKLQHELEEAEERADIAESQVNKLR 1927



 Score = 34.7 bits (78), Expect = 0.83
 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 13/118 (11%)

Query: 886  QLTYRVQRLQKKLEDQNKENHGLVE-------KLTSLAALRAGDVEKIQKLEAELEKAAT 938
            +L  RV+ L+ ++E + K N   V+       ++  L      D + I +L+  ++K   
Sbjct: 1820 KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQA 1879

Query: 939  HRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQL------KLQEKTEELKEKM 990
              ++Y+ + +   +     LAK +K   ELE  +E+  +      KL+ K+ E+  K+
Sbjct: 1880 KVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  608 bits (1569), Expect = e-173
 Identities = 454/1440 (31%), Positives = 718/1440 (49%), Gaps = 107/1440 (7%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            V++ +P+E +    I    R G KV  +  E G  L  +V  + + P+ NP       D+
Sbjct: 38   VFVAEPKESFVKGTIQS--REGGKVT-VKTEGGATL--TVKDDQVFPM-NPPKYDKIEDM 91

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              +++LHEPAVL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   +
Sbjct: 92   AMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQE 150

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189
              PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G       
Sbjct: 151  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEI 210

Query: 190  --------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYL 241
                    +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYL
Sbjct: 211  TSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270

Query: 242  LEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDR 300
            LEKSRVVFQ + ER+YHIFYQ+  S ++ E   + L +   ++Y  +  G   +  ++D+
Sbjct: 271  LEKSRVVFQLKAERSYHIFYQI-TSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329

Query: 301  AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360
             E++ T     +LGF  + ++ ++K+  A++H GN++      E  +  +          
Sbjct: 330  EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389

Query: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
            L  L S  + + LC  ++   +E V K  T  Q  NA  ALAK +Y  +F ++V RINQ 
Sbjct: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449

Query: 421  LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480
            L     +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 450  LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509

Query: 481  PWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
             WT IDF  D    I+LIE  MGI  +L+EEC+ P  TD ++  KLY+  + ++  F+KP
Sbjct: 510  EWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569

Query: 540  RM----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595
            ++    +   F + H+A  V+Y   G+LEKN+D + + +V + + S     A  F    T
Sbjct: 570  KVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQT 629

Query: 596  PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
                         AK+  K     F+ TV + FR +L  LM  L +T PH+VRCI PN+ 
Sbjct: 630  AEGEGAG----GGAKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684

Query: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713
            K P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E  F D 
Sbjct: 685  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744

Query: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
            K+  + +L  +  D  QY+FG TK+FF+AG +  LE++R DKL Q     Q   RG+L R
Sbjct: 745  KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804

Query: 774  KKFLR--ERRAALIIQQY-FRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830
             ++ R  ERR A+   QY  R    V+           W  +  +      L++S     
Sbjct: 805  VEYQRMVERREAIFCIQYNIRSFMNVK--------HWPWMKLFFKIK---PLLKSAETEK 853

Query: 831  RMATI--TMQAYSRGFLARRRYRKMLEEHKAVI--------LQKYARA-WLARRRFQSIR 879
             MAT+    Q            RK LEE    +        LQ  A A  LA    +  +
Sbjct: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913

Query: 880  RFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATH 939
                 IQL  +++ + ++ ED+ + N  L  K   L    +   + I  LE  L K    
Sbjct: 914  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973

Query: 940  RRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKM 990
            +   E K K   +    ++E +AKL K    L+   +Q    LQ + +++      K K+
Sbjct: 974  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033

Query: 991  DNLTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEK 1040
            +     L   +++E++ RM LE          K  +    D E + Q L E++K  + E 
Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093

Query: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100
              LQ  +E E      L+ ++  L  +   I E E+EIE  +A +   EK    Q+ ++ 
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QRSDLS 1146

Query: 1101 EKMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKKATRV 1150
             ++ EI+++L E     S  IE  + R +       DLE      E   A    K A  V
Sbjct: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1206

Query: 1151 LE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLT 1205
             E      + Q  K   EKE   +  ++  L+  +  + K       +  ++  +++ L 
Sbjct: 1207 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266

Query: 1206 SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALE 1265
            S+     + ++ I++L  Q+  L+    E + ++  K E L +QL R ++    Q + L+
Sbjct: 1267 SKE---EEQQRLINDLTAQRGRLQTESGEFSRQLDEK-EALVSQLSRGKQAFTQQIEELK 1322

Query: 1266 AQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEE 1323
             Q E   K K  L   +Q  +   D L++Q+E E E K   ++  S+   E      + E
Sbjct: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382

Query: 1324 LDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
             D   R  ++L++  K L++ +  A +   +   K     L+  ++     +++L+LD++
Sbjct: 1383 TDAIQRT-EELEEAKKKLAQRLQAAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMLDVE 1439



 Score = 77.8 bits (190), Expect = 9e-14
 Identities = 99/525 (18%), Positives = 222/525 (42%), Gaps = 45/525 (8%)

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
            T +++ L+++LE++ K  + L   L S      L     E+ Q+ +AEL++A        
Sbjct: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEV 1374

Query: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
            A  R  YE    +  + +EE   KL +     E   E +  K     E+ K+++ N  + 
Sbjct: 1375 AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCAS-LEKTKQRLQNEVED 1433

Query: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
            L  DV++       L+K           ++ K ++   ++++ ++E ++L  E  ++++ 
Sbjct: 1434 LMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNA 1493

Query: 1047 VEGEHVTSDGLKAEVARLSKQV-----------KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
             E      + LK E   L +++           K I E EK  + ++ +K +++  ++  
Sbjct: 1494 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1553

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +  +  +  +I +  LE   ++    R   E  E +++            ++T  L++  
Sbjct: 1554 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQST--LDAEI 1611

Query: 1156 QSQKDCY--EKEIEA-LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIP 1212
            +S+ D    +K++E  LN   + L+       +  R   +    ++     L        
Sbjct: 1612 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE 1671

Query: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNE 1269
            D K+Q++ +E++   L+  +    E+++  LE+       +++E  + ++R + L  QN 
Sbjct: 1672 DLKEQLAMVERRANLLQAEI----EELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727

Query: 1270 IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329
                 K+KL   I +MQ   + + ++     E       +A+ +  E +  ++     +R
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787

Query: 1330 VIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
            + K ++  VK L   + +A  +    G K+   +    RE E ++
Sbjct: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1832



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 97/511 (18%), Positives = 216/511 (42%), Gaps = 57/511 (11%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    + +A    +++  +S+   +  I+  Y  +    +LE   +EN 
Sbjct: 1452 QRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAY--EESLDQLETLKRENK 1509

Query: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
             L ++++ L    A   ++I +LE   ++    +   +   +    ++E +  K+ +   
Sbjct: 1510 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQL 1569

Query: 967  ELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKTQ 1020
            EL   K ++  K+ EK EE+ +   N   + + +   +  E R R   + L+K  E    
Sbjct: 1570 ELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1629

Query: 1021 DYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069
            + E Q+           ++ +     LKD ++ L   +  +    + LK ++A + ++  
Sbjct: 1630 EMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQ----EDLKEQLAMVERRAN 1685

Query: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128
             +   + EIE L+A     E+  +  ++E+ +    +  QLL + +   + ++  +E D+
Sbjct: 1686 LL---QAEIEELRATLEQTERSRKIAEQELLDASERV--QLLHTQNTSLINTKKKLETDI 1740

Query: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQK 1185
              +  +                +E   Q  ++  EK  +A+    +    L +E +    
Sbjct: 1741 SQMQGE----------------MEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784

Query: 1186 LFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244
            L R + ++ ++++    RL  +E + +   K+QI +LE + ++LE  +  + ++    ++
Sbjct: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK 1844

Query: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304
             L     R +E        L  Q E   K   +L D + ++Q      K+Q E   E   
Sbjct: 1845 GLRKHERRVKE--------LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 1305 NFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335
                +  +L  E  + EE  D+ +  + KL+
Sbjct: 1897 TNLAKFRKLQHELEEAEERADIAESQVNKLR 1927



 Score = 34.7 bits (78), Expect = 0.83
 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 13/118 (11%)

Query: 886  QLTYRVQRLQKKLEDQNKENHGLVE-------KLTSLAALRAGDVEKIQKLEAELEKAAT 938
            +L  RV+ L+ ++E + K N   V+       ++  L      D + I +L+  ++K   
Sbjct: 1820 KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQA 1879

Query: 939  HRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQL------KLQEKTEELKEKM 990
              ++Y+ + +   +     LAK +K   ELE  +E+  +      KL+ K+ E+  K+
Sbjct: 1880 KVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score =  608 bits (1568), Expect = e-173
 Identities = 449/1439 (31%), Positives = 718/1439 (49%), Gaps = 109/1439 (7%)

Query: 14   WIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDLT 73
            ++ D +E++    I    R  DKV+   L+D      ++N + + P+ NP       D+ 
Sbjct: 39   FVADNKEMYVKGMIQT--RENDKVIVKTLDDRM---LTLNNDQVFPM-NPPKFDKIEDMA 92

Query: 74   ALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDM 133
             +++LHEPAVL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   + 
Sbjct: 93   MMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEA 151

Query: 134  DPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH---- 189
             PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G        
Sbjct: 152  PPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQP 211

Query: 190  ------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243
                  +ED+++ +NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYLLE
Sbjct: 212  GKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 271

Query: 244  KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRAE 302
            KSRV FQ  +ER+YHIFYQ+ ++ ++ E   L L S   F++  +  G   +  ++D  E
Sbjct: 272  KSRVTFQLSSERSYHIFYQIMSN-KKPELIDLLLISTNPFDFPFVSQGEVTVASIDDSEE 330

Query: 303  MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362
            ++ T     +LGF  + ++ ++K+  A++H GN++      E  +  +          L+
Sbjct: 331  LLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLM 390

Query: 363  GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422
            GL S  + + LC  ++   +E V K     Q  N+  ALAK +Y  +F ++V RINQ L 
Sbjct: 391  GLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD 450

Query: 423  FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 451  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510

Query: 483  TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR- 540
              IDF  D    I+LIE  MGI  +L+EEC+ P  TD ++  KLY+  + ++  F+KP+ 
Sbjct: 511  EFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKP 570

Query: 541  ---MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597
                +   F + H+A  V+Y   G+L+KN+D + + +V + + S   L +  F       
Sbjct: 571  AKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF------- 623

Query: 598  SPFGSMITVKS--AKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
            S +    T  S  +K+  K     F+ TV + FR +L  LM  L +T PH+VRC+ PN+ 
Sbjct: 624  SNYAGAETGDSGGSKKGGKKKGSSFQ-TVSAVFRENLNKLMTNLRSTHPHFVRCLIPNET 682

Query: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713
            K P   D   ++ QLR  GVLE IRI  + +PSR  Y +F  RY IL      E  F D 
Sbjct: 683  KTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDS 742

Query: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
            K   + +L+ +  D  Q++FG TK+FF+AG +  LE++R +KL       Q   RG+L R
Sbjct: 743  KNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMR 802

Query: 774  ---KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830
               KK +  R +   IQ   R    V+           W  +  +      L++S     
Sbjct: 803  VEFKKMMERRDSIFCIQYNIRSFMNVK--------HWPWMNLFFKIK---PLLKSAEAEK 851

Query: 831  RMATITMQ-AYSRGFLAR-RRYRKMLEEHKAVILQKYARAWL-----------ARRRFQS 877
             MAT+      ++  LAR    RK LEE    +LQ+     L           A  R + 
Sbjct: 852  EMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEG 911

Query: 878  IRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAA 937
            + +    I L  +V+ L ++LE++ + N  LV K  +L    +     I  LE  L K  
Sbjct: 912  LIK--SKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVE 969

Query: 938  THRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQ-----------------IQL 977
              +   E K K   +   A+EE ++KL K    L+   +Q                 I  
Sbjct: 970  KEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINA 1029

Query: 978  KLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALK 1037
            KL+++T++L+  ++   K+L  D+++ +R+     K  +    D E   Q ++E++K  +
Sbjct: 1030 KLEQQTDDLEGSLEQ-EKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKE 1088

Query: 1038 DEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKR 1097
             E  QLQ  ++ E V S   + ++  L  +   I E E+EIE     +  +EK      R
Sbjct: 1089 FELSQLQAKIDDEQVHSLQFQKKIKELQAR---IEELEEEIEAEHTLRAKIEKQRSDLAR 1145

Query: 1098 EMR------EKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVL 1151
            E+       E+ S  T   +E     +   +    DLE      E   A    K+A  V 
Sbjct: 1146 ELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVA 1205

Query: 1152 E-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTS 1206
            E      + Q  K   EKE   L  ++  ++  I  L K    +++I  + R    + + 
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSK---SKSNIERTCRTVEDQFSE 1262

Query: 1207 ENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEA 1266
                     Q I +L  QK  L+ +  E + +++ K E L +QL +S++    Q + L+ 
Sbjct: 1263 IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEK-ESLISQLTKSKQALTQQLEELKR 1321

Query: 1267 QNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEEL 1324
            Q E  TK K  +   +Q  +   D L++Q+E E E K   ++  S+   E      + E 
Sbjct: 1322 QMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYET 1381

Query: 1325 DMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
            D   R  ++L++  K L++ + +A +   ++  K     L+  ++     +++L+ DL+
Sbjct: 1382 DAIQRT-EELEEAKKKLAQRLQEAEENTETANSK--CASLEKTKQRLQGEVEDLMRDLE 1437



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 117/535 (21%), Positives = 240/535 (44%), Gaps = 63/535 (11%)

Query: 887  LTYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA------- 936
            LT +++ L++++E++ K  + +   L S      L     E+ Q+ +AEL++A       
Sbjct: 1312 LTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSE 1371

Query: 937  -ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLK---LQEKTEELKEKMDN 992
             A  R  YE    +  + +EE   KL +   E E   E    K   L++  + L+ ++++
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVED 1431

Query: 993  LTKQL----------------FDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKAL 1036
            L + L                FD V  E +Q+ L E   EL+    +K+ +SL  E+  +
Sbjct: 1432 LMRDLERSHTACATLDKKQRNFDKVLAEWKQK-LDESQAELEAA--QKESRSLSTELFKM 1488

Query: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHV 1092
            ++   ++   +E     +  L+ E++ L++Q+    K + E EK  +L++ +K D++  +
Sbjct: 1489 RNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL 1548

Query: 1093 QSQKREMREKMSEITKQLLESYDIEDVRSRLSVE---DLEHLNEDGELWFAYEGLKKATR 1149
            +  +  +  + S+I +  LE   ++    R  +E   ++E L  + +   A E L+    
Sbjct: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQR--AAEALQS--- 1603

Query: 1150 VLESHFQSQKDCY------EKEIEALNFKVVHLSQEINHLQKLFRE-ENDINESIRHEVT 1202
            VL++  +S+ D        E ++  +  ++ H ++++   QK  R  +  + +S  H   
Sbjct: 1604 VLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDD 1663

Query: 1203 RLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQ 1260
             L S      D K+Q++ +E++       L E+ E+MK  LE+       S++E  + + 
Sbjct: 1664 ALRSNE----DLKEQLAIVERRNG----LLLEELEEMKVALEQTERTRRLSEQELLDASD 1715

Query: 1261 R-KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD 1319
            R + L +QN      K+KL   I + Q   ++  ++     E       +A+ +  E + 
Sbjct: 1716 RVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKK 1775

Query: 1320 LEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
             ++     +R+ K L+  VK L   + +A  +    G K+   +    RE E +L
Sbjct: 1776 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENEL 1830



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 119/574 (20%), Positives = 242/574 (42%), Gaps = 118/574 (20%)

Query: 845  LARRRYRKMLEEHKAVILQKYARA------WLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898
            L R +Y +  +E KA + +  ++A      W  +    +I+R     +L    ++L ++L
Sbjct: 1346 LLREQYEEE-QEAKAELQRALSKANSEVAQWRTKYETDAIQR---TEELEEAKKKLAQRL 1401

Query: 899  EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKL 958
            ++  +       K  SL   +     +++ L  +LE++ T     ++K + +   + E  
Sbjct: 1402 QEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWK 1461

Query: 959  AKLQKHNSELE-TQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFEL 1017
             KL +  +ELE  QKE   L  +        KM N  +++ D                  
Sbjct: 1462 QKLDESQAELEAAQKESRSLSTE------LFKMRNAYEEVVD------------------ 1497

Query: 1018 KTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKE 1077
                   Q+++L+ E K L++E   L      E +   G            K + E EK 
Sbjct: 1498 -------QLETLRRENKNLQEEISDLT-----EQIAETG------------KNLQEAEKT 1533

Query: 1078 IELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSV---EDLEHLNED 1134
             +L++ +K D++  ++  +  +  + S+I +  LE   ++    R  +   E++E L  +
Sbjct: 1534 KKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRN 1593

Query: 1135 GELWFAYEGLKKATRVLESHFQSQKDC------YEKEIEALNFKVVHLSQEINHLQKLFR 1188
             +   A E L+    VL++  +S+ D        E ++  +  ++ H ++++   QK  R
Sbjct: 1594 SQR--AAEALQS---VLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLR 1648

Query: 1189 E-ENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELS 1247
              +  + +S  H    L S      D K+Q++ +E++       L E+ E+MK  LE+  
Sbjct: 1649 TVQGQLKDSQLHLDDALRSNE----DLKEQLAIVERRNG----LLLEELEEMKVALEQTE 1700

Query: 1248 NQLHRSQEE--EGTQR-KALEAQNE--IHTKEK---------EKLIDKIQEMQEASDHLK 1293
                 S++E  + + R + L +QN   I+TK+K          ++ + IQE + A +  K
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760

Query: 1294 K----------QFETESEVKCNFRQEASRLTLENRDLEEELDMKDRV--------IKKLQ 1335
            K          + + E +   +  +    L    +DL+  LD  +++        I+KL+
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820

Query: 1336 DQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRE 1369
            ++V+ L   +    DV    G +   G  +Y+R+
Sbjct: 1821 NRVRELENEL----DVEQKRGAEALKGAHKYERK 1850


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score =  608 bits (1568), Expect = e-173
 Identities = 444/1430 (31%), Positives = 730/1430 (51%), Gaps = 92/1430 (6%)

Query: 14   WIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDLT 73
            ++PD +E +  A+I    R G KV+    E+G  +      E     +NP       D+ 
Sbjct: 38   FVPDDKEEFVKAKILS--REGGKVIAET-ENGKTVTVK---EDQVLQQNPPKFDKIEDMA 91

Query: 74   ALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDM 133
             L++LHEPAVL NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   + 
Sbjct: 92   MLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEA 150

Query: 134  DPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVS-------KSGS 186
             PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFA+++       K  +
Sbjct: 151  PPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNA 210

Query: 187  NAH---VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243
            NA+   +ED+++ +NP  EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYLLE
Sbjct: 211  NANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 270

Query: 244  KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRAE 302
            KSRV+FQ + ERNYHIFYQ+ ++ ++ E   + L +   ++Y  +  G   +  ++D  E
Sbjct: 271  KSRVIFQLKAERNYHIFYQILSN-KKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEE 329

Query: 303  MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362
            ++ T   F +LGF  + +  V+K+  AI+H GN++      E  +  +          L+
Sbjct: 330  LMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLM 389

Query: 363  GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422
            GL S  + + LC+ ++   +E V K  +  Q   +  ALAK +Y  +F+++V RIN  L+
Sbjct: 390  GLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE 449

Query: 423  FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                +  FIGVLDI GFE FD NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 450  TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509

Query: 483  TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR- 540
            T IDF  D Q  IDLIE  MGI+ +L+EEC+ P  TD  +  KLY+N + ++  F+KPR 
Sbjct: 510  TFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN 569

Query: 541  ---MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597
                    F + H+A  V+Y   G+LEKN+D + + +V + + S   L A  F       
Sbjct: 570  IKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLF------- 622

Query: 598  SPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKL 657
            S + +  T  S K            TV +  R +L  LM  L  T PH+VRCI PN+ K 
Sbjct: 623  SSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKA 682

Query: 658  PFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MTKQELSFSDKKE 715
            P   D+  ++ QLR  GVLE IRI  + +P+R  Y +F  RY IL  +   E  F D ++
Sbjct: 683  PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRK 742

Query: 716  VCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR-- 773
              + +L  L  D NQY+FG TK+FF+AG +  LE++R ++L +    +Q   RG L R  
Sbjct: 743  GTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIE 802

Query: 774  -KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRM 832
             KK +  R A L+IQ   R    V K    + L      ++        +     +  R+
Sbjct: 803  FKKIVERRDALLVIQWNIRAFMGV-KNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRI 861

Query: 833  ATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLN-IQLTYRV 891
                 ++ +R      +   +L+E   + LQ  A         +   + + N IQL  +V
Sbjct: 862  KETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKV 921

Query: 892  QRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYR 951
            + + ++LED+ + N  L  K   L    +   + I  LE  L K    +   E K K   
Sbjct: 922  KEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 981

Query: 952  D---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKMDNLTKQLFDDVQ 1002
            +    ++E +AKL K    L+   +Q    LQ + +++      K K++     L   ++
Sbjct: 982  EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLE 1041

Query: 1003 KEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEH--VTSDGLKAE 1060
            +E++ RM LE++     +  E  ++  +E I  L+++K+QL+  ++ +   +     K E
Sbjct: 1042 QEKKVRMDLERA----KRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097

Query: 1061 -----VARLSKQVK----TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLL 1111
                   +L K++K     I E E+E+E  +  +  VEK     + ++  ++ EI+++L 
Sbjct: 1098 DEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEK----LRSDLSRELEEISERLE 1153

Query: 1112 ESYDIEDVRSRLSVE----------DLEHLNEDGELWFAYEGLKKATRVLE-----SHFQ 1156
            E+     V+  ++ +          DLE      E   A    K A  V E      + Q
Sbjct: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQ 1213

Query: 1157 SQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQ 1216
              K   EK  E   FK + L    ++++++ + + ++ +  R    +     + + + ++
Sbjct: 1214 RVKQKLEK--EKSEFK-LELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270

Query: 1217 QISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKE 1276
             +++   Q+  L+    E A +++ K E L +QL R +     Q + L+ Q E   K K 
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEK-EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329

Query: 1277 KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEELDMKDRVIKKL 1334
             L   +Q  +   D L++Q+E E+E K   ++  S+   E      + E D   R  ++L
Sbjct: 1330 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT-EEL 1388

Query: 1335 QDQVKTLSKTIGKAND-VHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
            ++  K L++ +  A + V + +     L   +++ ++E   I++L++D++
Sbjct: 1389 EEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE---IEDLMVDVE 1435



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 115/550 (20%), Positives = 242/550 (44%), Gaps = 89/550 (16%)

Query: 885  IQLTYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA----- 936
            +  T +++ L+++LE++ K  + L   L S      L     E+  + +AEL++      
Sbjct: 1308 LSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN 1367

Query: 937  ---ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNL 993
               A  R  YE    +  + +EE   KL +   + E   E +  K     E+ K ++ N 
Sbjct: 1368 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS-LEKTKHRLQNE 1426

Query: 994  TKQLFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQL 1043
             + L  DV++       L+K           ++ K ++ + +++S ++E ++L  E  +L
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 1486

Query: 1044 QHLVEG--EHVTS-----DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHV 1092
            ++  E   EH+ +       L+ E++ L++Q+    K + E EK  + L+ +K++++  +
Sbjct: 1487 KNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSAL 1546

Query: 1093 QSQKREMREKMSEITKQLLESYDIE-DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVL 1151
            +  +  +  +  +I +  LE   I+ ++  +L+ +D              E +++A R  
Sbjct: 1547 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD--------------EEMEQAKRNH 1592

Query: 1152 ESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMI 1211
            +    S +   + E  + N        E+  ++K  + E D+NE       +L+  N M 
Sbjct: 1593 QRVVDSLQTSLDAETRSRN--------EVLRVKK--KMEGDLNEM----EIQLSHANRMA 1638

Query: 1212 PDFKQQISELEKQKQDLEIRL------NEQAEKMKGKLEELSNQLHRSQEE-----EGTQ 1260
             + ++Q+  L+   +D +I+L      N+  ++    +E  +N L    EE     E T+
Sbjct: 1639 AEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE 1698

Query: 1261 RKALEAQNE-IHTKEKEKLIDKI------QEMQEASDHLKKQFETESEVK-CNFRQEASR 1312
            R    A+ E I T E+ +L+         Q+ +  SD  + Q E E  V+ C   +E ++
Sbjct: 1699 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAK 1758

Query: 1313 LTLEN-----RDLEEELDMK---DRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGML 1364
              + +      +L++E D     +R+ K ++  +K L   + +A  +    G K+   + 
Sbjct: 1759 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLE 1818

Query: 1365 QYKREDEAKL 1374
               RE E +L
Sbjct: 1819 ARVRELEGEL 1828



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 112/534 (20%), Positives = 226/534 (42%), Gaps = 73/534 (13%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    +  +    +++  +S+   +  ++  Y  +   + LE   +EN 
Sbjct: 1448 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENK 1505

Query: 907  GLVEKLTSLAA-LRAG--DVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
             L E+++ L   L  G  +V +++K+  +LE      ++  E+ +    ++E +  K+ +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEA---SLEHEEGKILR 1562

Query: 964  HNSELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFEL 1017
               E    K +I+ KL EK EE+++   N   +   L   +  E R R   + ++K  E 
Sbjct: 1563 AQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEG 1622

Query: 1018 KTQDYE--------------KQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVAR 1063
               + E              KQ++SL+     LKD ++QL   V      +D LK  +A 
Sbjct: 1623 DLNEMEIQLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVR----ANDDLKENIAI 1675

Query: 1064 LSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRL 1123
            + ++   +   + E+E L+A     E+  +  ++E+ E    +  QLL S +   +  + 
Sbjct: 1676 VERRNNLL---QAELEELRAVVEQTERSRKLAEQELIETSERV--QLLHSQNTSLINQKK 1730

Query: 1124 SVE-DLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALN---FKVVHLSQE 1179
             +E DL  L  +                +E   Q  ++  EK  +A+         L +E
Sbjct: 1731 KMESDLTQLQSE----------------VEEAVQECRNAEEKAKKAITDAAMMAEELKKE 1774

Query: 1180 INHLQKLFREENDINESIRHEVTRL-TSENMMIPDFKQQISELEKQKQDLEIRLNEQAEK 1238
             +    L R + ++ ++I+    RL  +E + +   K+Q+ +LE + ++LE  L  + ++
Sbjct: 1775 QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKR 1834

Query: 1239 MKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFET 1298
                ++ +     R +E        L  Q E   K   +L D + ++Q      K+Q E 
Sbjct: 1835 NAESVKGMRKSERRIKE--------LTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886

Query: 1299 ESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVH 1352
              E       +  ++  E  + EE  D+ +  + KL    +  S+ IG    +H
Sbjct: 1887 AEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL----RAKSRDIGAKQKMH 1936


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score =  608 bits (1567), Expect = e-173
 Identities = 441/1438 (30%), Positives = 722/1438 (50%), Gaps = 108/1438 (7%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            V++ +P+E +  + I    + G KV  +  E G  L  +V  + + P+ NP       D+
Sbjct: 40   VFVAEPKESYVKSTIQS--KEGGKVT-VKTEGGATL--TVREDQVFPM-NPPKYDKIEDM 93

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              +++LHEP VL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   +
Sbjct: 94   AMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQE 152

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189
              PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G       
Sbjct: 153  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDES 212

Query: 190  ------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243
                  +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYLLE
Sbjct: 213  GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 244  KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRAE 302
            KSRV FQ + ER+YHIFYQ+  S ++ +   + L +   ++Y  +  G   +  ++D+ E
Sbjct: 273  KSRVTFQLKAERSYHIFYQI-TSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEE 331

Query: 303  MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362
            ++ T     +LGF  + ++ ++K+  A++H GN++      E  +  +          L 
Sbjct: 332  LMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQ 391

Query: 363  GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422
             L S  + + LC  ++   +E V K  T  Q  NA  ALAK +Y  +F ++V RINQ L 
Sbjct: 392  SLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD 451

Query: 423  FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 483  TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541
            T IDF  D    I+LIE  +GI  +L+EEC+ P  TD ++  KLY+  + ++  F+KP++
Sbjct: 512  TFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKV 571

Query: 542  ----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597
                +   F + H+A  V+Y   G+L+KN+D + D +V + + S     A+ F       
Sbjct: 572  VKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLF------- 624

Query: 598  SPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKL 657
            S + S     SAK+  K     F+ TV + FR +L  LM  L +T PH+VRCI PN+ K 
Sbjct: 625  STYASAEADSSAKKGAKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKT 683

Query: 658  PFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDKKE 715
            P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E  F D K+
Sbjct: 684  PGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKK 743

Query: 716  VCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR-- 773
              + +L  +  D  QY+FG TK+FF+AG +  LE++R +KL Q     Q   RG+L R  
Sbjct: 744  ASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVE 803

Query: 774  -KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRM 832
             +K L+ R A   IQ   R    V+           W  +  +      L++S      M
Sbjct: 804  YQKMLQRREALFCIQYNVRAFMNVK--------HWPWMKLFFKIK---PLLKSAETEKEM 852

Query: 833  ATI------TMQAYSRGFLARRRYRK----MLEEHKAVILQKYARAWLARRRFQSIRRFV 882
            AT+      T    ++    R+   +    +L+E   + LQ  + A       +   + +
Sbjct: 853  ATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLI 912

Query: 883  LN-IQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRR 941
             N IQL  +++ + ++ E++ + N  L  K   L    +   + I  LE  L K    + 
Sbjct: 913  KNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 972

Query: 942  NYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKMDN 992
              E K K   +    ++E +AKL K    L+   +Q    LQ + +++      K K++ 
Sbjct: 973  ATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQ 1032

Query: 993  LTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEKMQ 1042
                L   +++E++ RM LE          K  +  T D E   Q L E+++  + E   
Sbjct: 1033 QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISN 1092

Query: 1043 LQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREK 1102
            L   +E E      L+ ++  L  +++ + E   EIE  +A +   EK    Q+ ++  +
Sbjct: 1093 LISKIEDEQAVEIQLQKKIKELQARIEELGE---EIEAERASRAKAEK----QRSDLSRE 1145

Query: 1103 MSEITKQLLESYDIEDVRSRLSVE----------DLEHLNEDGELWFAYEGLKKATRVLE 1152
            + EI+++L E+      +  L+ +          DLE      E   A    K A  + E
Sbjct: 1146 LEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAE 1205

Query: 1153 -----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSE 1207
                  + Q  K   EKE   L  +   LS     + K       +  S+  +V+ L ++
Sbjct: 1206 LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK 1265

Query: 1208 NMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQ 1267
                 + ++ I++L  Q+  L+    E + ++  K + L +QL RS++    Q + L+ Q
Sbjct: 1266 E---EEQQRLINDLTAQRARLQTEAGEYSRQLDEK-DALVSQLSRSKQASTQQIEELKHQ 1321

Query: 1268 NEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEELD 1325
             E  TK K  L   +Q  +   D L++Q+E E E K   ++  S+   E      + E D
Sbjct: 1322 LEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 1381

Query: 1326 MKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
               R  ++L++  K L++ + +A +   +   K     L+  ++     +++L+LD++
Sbjct: 1382 AIQRT-EELEEAKKKLAQRLQEAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMLDVE 1436



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 123/482 (25%), Positives = 207/482 (42%), Gaps = 69/482 (14%)

Query: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY 950
            +QR+++KLE +  E     + L+S       + E I K +  LEK     R+ E++    
Sbjct: 1213 LQRVKQKLEKEKSELKMETDDLSS-------NAEAISKAKGNLEKMC---RSLEDQVSEL 1262

Query: 951  RDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRML 1010
            +   EE+    Q+  ++L  Q+ ++Q +  E + +L EK D L  Q              
Sbjct: 1263 KTKEEEQ----QRLINDLTAQRARLQTEAGEYSRQLDEK-DALVSQ-------------- 1303

Query: 1011 LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGL----------KAE 1060
            L +S +  TQ  E+    L+EE KA    K  L H ++      D L          KAE
Sbjct: 1304 LSRSKQASTQQIEELKHQLEEETKA----KNALAHALQSSRHDCDLLREQYEEEQEGKAE 1359

Query: 1061 VAR-LSKQVKTISEFEKEIE---LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDI 1116
            + R LSK    ++++  + E   + + ++++  K   +Q+ +  E+  E       S + 
Sbjct: 1360 LQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEK 1419

Query: 1117 EDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEK---EIEALNFKV 1173
               R +  VEDL    E      A   L K  R  +      K  YE+   E+EA   + 
Sbjct: 1420 TKQRLQNEVEDLMLDVERSNA--ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES 1477

Query: 1174 VHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLN 1233
              LS E+  ++ ++ E  D  E++R E   L  E   I D  +QI+E  KQ  +LE ++ 
Sbjct: 1478 RSLSTELFKVKNVYEESLDQLETLRRENKNLQQE---ISDLTEQIAEGGKQIHELE-KIK 1533

Query: 1234 EQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLK 1293
            +Q E+ K +++    +   S E E  + K L  Q E++ + K ++  KI E  E  D LK
Sbjct: 1534 KQVEQEKCEIQAALEEAEASLEHE--EGKILRIQLELN-QVKSEVDRKIAEKDEEIDQLK 1590

Query: 1294 KQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHS 1353
            +      E         S L  E R   + L    RV KK++  +  +   +  AN + +
Sbjct: 1591 RNHTRVVETM------QSTLDAEIRSRNDAL----RVKKKMEGDLNEMEIQLNHANRLAA 1640

Query: 1354 SS 1355
             S
Sbjct: 1641 ES 1642



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 112/572 (19%), Positives = 248/572 (43%), Gaps = 79/572 (13%)

Query: 850  YRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909
            Y + L+E  A++ Q      L+R +  S          T +++ L+ +LE++ K  + L 
Sbjct: 1290 YSRQLDEKDALVSQ------LSRSKQAS----------TQQIEELKHQLEEETKAKNALA 1333

Query: 910  EKLTSL---AALRAGDVEKIQKLEAELEKA--------ATHRRNYEEKGKRYRDAVEEKL 958
              L S      L     E+ Q+ +AEL++A        A  R  YE    +  + +EE  
Sbjct: 1334 HALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1393

Query: 959  AKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS---- 1014
             KL +   E E   E +  K     E+ K+++ N  + L  DV++       L+K     
Sbjct: 1394 KKLAQRLQEAEEHVEAVNAKCAS-LEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNF 1452

Query: 1015 ------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGE-------HVTSDGLKAEV 1061
                  ++ K ++ + ++++ ++E ++L  E  +++++ E            +  L+ E+
Sbjct: 1453 DKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512

Query: 1062 ARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIE 1117
            + L++Q+    K I E EK  + ++ +K +++  ++  +  +  +  +I +  LE   ++
Sbjct: 1513 SDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572

Query: 1118 DVRSRLSVEDLEHLNEDGELWFAYEGLKKA-TRVLESHFQSQKDCYEKEIEALNFKVVHL 1176
                R   E  E +++          LK+  TRV+E+  QS  D    EI + N  +   
Sbjct: 1573 SEVDRKIAEKDEEIDQ----------LKRNHTRVVET-MQSTLDA---EIRSRNDALRVK 1618

Query: 1177 SQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRL---N 1233
             +    L ++  + N  N      +    +   ++ + +  + +  + ++DL+ +L    
Sbjct: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678

Query: 1234 EQAEKMKGKLEELSNQLHRSQEEEG-TQRKALEAQNEI---HTKEKEKLIDKIQEMQEAS 1289
             +A  ++ ++EEL   L +++      +++ L+A   +   HT +   LI+  ++++   
Sbjct: 1679 RRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHT-QNTSLINTKKKLENDV 1737

Query: 1290 DHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMK-------DRVIKKLQDQVKTLS 1342
              L+ + E   +   N  ++A +   +   + EEL  +       +R+ K L+  VK L 
Sbjct: 1738 SQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1797

Query: 1343 KTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
              + +A  +    G K+   +    RE E ++
Sbjct: 1798 HRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1829



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 95/511 (18%), Positives = 213/511 (41%), Gaps = 57/511 (11%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    +  A    +++  +S+   +  ++  Y  +    +LE   +EN 
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVY--EESLDQLETLRRENK 1506

Query: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
             L ++++ L    A   ++I +LE   ++    +   +   +    ++E +  K+ +   
Sbjct: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566

Query: 967  ELETQKEQIQLKLQEKTEELKEKMDNLTKQL------FDDVQKEERQRMLLEKSFELKTQ 1020
            EL   K ++  K+ EK EE+ +   N T+ +       D   +     + ++K  E    
Sbjct: 1567 ELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLN 1626

Query: 1021 DYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069
            + E Q+           ++ +     LK+ ++ L   + G+    + LK ++A + ++  
Sbjct: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQ----EDLKEQLAIVERRAN 1682

Query: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128
             +   + EIE L A     E+  +  ++E+ +    +  QLL + +   + ++  +E D+
Sbjct: 1683 LL---QAEIEELWATLEQTERSRKIAEQELLDASERV--QLLHTQNTSLINTKKKLENDV 1737

Query: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQK 1185
              L  +                +E   Q  ++  EK  +A+    +    L +E +    
Sbjct: 1738 SQLQSE----------------VEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1781

Query: 1186 LFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244
            L R + ++ ++++    RL  +E + +   K+QI +LE + ++LE  +  + ++    ++
Sbjct: 1782 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVK 1841

Query: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304
             L     R +E        L  Q E   K   +L D + ++Q      K+Q E   E   
Sbjct: 1842 GLRKHERRVKE--------LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1893

Query: 1305 NFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335
                +  +L  E  + EE  D+ +  + KL+
Sbjct: 1894 ANLSKFRKLQHELEEAEERADIAESQVNKLR 1924


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score =  607 bits (1565), Expect = e-173
 Identities = 437/1418 (30%), Positives = 717/1418 (50%), Gaps = 137/1418 (9%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            VW+P  ++ +++A I ++   GD+V+  L+E+G ++  +V  + +  + NP       D+
Sbjct: 36   VWVPSEKQGFEAASIKEEK--GDEVVVELVENGKKV--TVGKDDIQKM-NPPKFSKVEDM 90

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 91   AELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHE 149

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----- 187
            M PHI+A+A+ AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S        
Sbjct: 150  MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209

Query: 188  --AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKS 245
                +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ TYLLEKS
Sbjct: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269

Query: 246  RVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTV-IEGVNDRAEMV 304
            R + Q+ +ER +HIFY + A A++     L L      NYT +    V I    D     
Sbjct: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQ 327

Query: 305  ETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLGL 364
            ET +   ++GF E+ Q+ + K+++++L LGN+      N   +   D++  +  C L+G+
Sbjct: 328  ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387

Query: 365  ESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQFS 424
                  + +   +I    + V K  T+ QA  A +ALAK  Y  LF +I+ R+N+AL  +
Sbjct: 388  NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 447

Query: 425  GKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWT 483
             +Q  +F+G+LDI GFE F+VNSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W 
Sbjct: 448  HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507

Query: 484  LIDF-YDNQPVIDLIEA---KMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
             IDF  D QP I+LIE      G+L LLDEEC  P  TD+++++KL       +P F+KP
Sbjct: 508  FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE-QGSHPKFQKP 566

Query: 540  RM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQE-NPTP 596
            +     T F I H+A KV+Y    +L KN D + D +  +L AS     A+ +++ +   
Sbjct: 567  KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626

Query: 597  PSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEK 656
                 + +T  S     K     FR TVG  ++  L  LM TL  TTP++VRCI PN EK
Sbjct: 627  GLDQMAKMTESSLPSASKTKKGMFR-TVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685

Query: 657  LPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKKE 715
               + D+  +++QLR  GVLE IRI  Q +P+R  + EF  RY IL        F D K+
Sbjct: 686  RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQ 745

Query: 716  VCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKK 775
             C +++  L  D N Y+ G++KIFFR G +A+LE+ R  K+    +  Q   RG+L RK 
Sbjct: 746  ACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKA 805

Query: 776  FLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMAT- 834
            F + ++           Q T  K              +IQ++C  YL    +Q  R+ T 
Sbjct: 806  FAKRQQ-----------QLTAMK--------------VIQRNCAAYLKLRNWQWWRLFTK 840

Query: 835  ------ITMQ-------------AYSRGFLARRRYRKMLEEHKAV-----ILQKYARA-- 868
                  +T Q                R   A    +++ ++H  +     +LQ+  +A  
Sbjct: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900

Query: 869  -WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQ 927
               A      +R      +L   +  ++ +LE++      L  +   +A       E+++
Sbjct: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960

Query: 928  KLEAELEKAATHRRNYEEKGKRYRDAV---EEKLAKLQKHNSELETQKEQIQLKLQEKTE 984
            + EA  +K    +   E K K+  D +   +++  KL K    LE +   +   L E+ E
Sbjct: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020

Query: 985  ------ELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLKEEIKA 1035
                  +LK K +++  +L   ++KEE+ R  LEK     E    D+ +QI  L+ +I  
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080

Query: 1036 LKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK----H 1091
            L   KMQL    E        L  E+A+ +  +K I E E  I  LQ + +D E+     
Sbjct: 1081 L---KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARNK 1136

Query: 1092 VQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVL 1151
             + QKR++ E++  +  +L ++ D    +  L  +       + E+    + L + TR  
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAK------REQEVTVLKKALDEETRSH 1190

Query: 1152 ESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMI 1211
            E+  Q  +  + + +E        L++++   ++     +   +++  E   L  E  ++
Sbjct: 1191 EAQVQEMRQKHAQAVE-------ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243

Query: 1212 PDFKQQI----SELEKQKQDLEIR----------LNEQAEKMKGKLEELSNQLHRSQ--- 1254
               KQ++     +LE Q Q+L+ +          LN++  K++ ++E ++  L+ ++   
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA 1303

Query: 1255 ----EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFR 1307
                ++  +    L+   E+    T++K  +  K+++++E  + L+ Q + E E K N  
Sbjct: 1304 IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLE 1363

Query: 1308 QEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
            +  S L ++  D +++L      ++ L++  K   K I
Sbjct: 1364 RHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1401



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 97/507 (19%), Positives = 217/507 (42%), Gaps = 51/507 (10%)

Query: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGD-VEKIQK-L 929
            +R+F  +     NI   Y  +R + + E + KE   L        AL A + +E+  K L
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509

Query: 930  EAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKE- 988
            +AE+E   + +           D V + + +L+K    LETQ E+++ +L+E  +EL+  
Sbjct: 1510 KAEMEDLVSSK-----------DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558

Query: 989  ---------KMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDE 1039
                      M  L  Q   D+Q  + Q     +  + +  +YE +++  +++       
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618

Query: 1040 KMQLQHLVEGEHVTSD----GLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
            K +L+  ++   + +D    G +  + +L K    + +F++E+E  +A + ++    +  
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +++ +   +++ +   +    E  R +  +E  E   E          L+   R LE+  
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738

Query: 1156 QSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDI---NESIRHEVTRLTSENM 1209
               ++  E+E   +EA++ +V   +Q+   L      E      NES R ++ R      
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN---- 1794

Query: 1210 MIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269
                 K+  S+L + +  ++ +       ++ K+ +L  Q+ +   E+    K+L+ +++
Sbjct: 1795 -----KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849

Query: 1270 ------IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEE 1323
                  +  +++ K+ ++ +E  E  +   KQ + + E      +E+ R+    R L+ E
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE---EAEEESQRINANRRKLQRE 1906

Query: 1324 LDMKDRVIKKLQDQVKTLSKTIGKAND 1350
            LD      + +  +V  L   + + N+
Sbjct: 1907 LDEATESNEAMGREVNALKSKLRRGNE 1933



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 106/476 (22%), Positives = 205/476 (43%), Gaps = 77/476 (16%)

Query: 886  QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945
            QL      LQ +L+++ +    L   +++L    +   +K+Q   + +E     ++ +++
Sbjct: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399

Query: 946  KGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEE 1005
            + +      EEK A   K         E+ + +LQ++ ++L   +DN  +QL  +++K++
Sbjct: 1400 EIENLTQQYEEKAAAYDK--------LEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQ 1450

Query: 1006 R---QRMLLEKSFELKTQDY--EKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAE 1060
            R   Q +  EK+   K  D     + ++ ++E KAL   +  L+  +E         K E
Sbjct: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR-ALEEALEA--------KEE 1501

Query: 1061 VARLSKQVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLESYDIE 1117
            + R +K +K       E+E L + K DV K+V   +  KR +  +M E+  QL E     
Sbjct: 1502 LERTNKMLKA------EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE----- 1550

Query: 1118 DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLS 1177
                   +ED     ED +L             LE + Q+ K  +E++++A + +     
Sbjct: 1551 -------LEDELQATEDAKL------------RLEVNMQALKGQFERDLQARDEQNEEKR 1591

Query: 1178 QEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAE 1237
            +++   ++L   E ++ +  +       ++  +  D K    +LE Q  D  I+  E+A 
Sbjct: 1592 RQLQ--RQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQ-ADSAIKGREEAI 1644

Query: 1238 KMKGKLEELSNQLHRSQEEEGTQRKALEA---QNEIHTKEKEKLIDKIQEMQEASDHLKK 1294
            K   KL+       R  E+    R  + A   +NE   K  E  + ++QE   A++  +K
Sbjct: 1645 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704

Query: 1295 QFETESEVKCN-----------FRQEASRLTLENRDLEEELDMKDRVIKKLQDQVK 1339
            Q + E E                + E  RL      LEEEL+ +   ++ + D+V+
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)

Query: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
            +Q  E++ ++ +L+ +  E+ +K + +L+EL  +  +  EE+   ++ L+A+ E++ + +
Sbjct: 849  RQEEEMQAKEDELQ-KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907

Query: 1276 E---KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIK 1332
            E   +L  K QE++E    ++ + E E +     + E  ++  +  DLEE+L+ ++   +
Sbjct: 908  EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967

Query: 1333 KLQDQVKTLSKTIGKANDVHSSSGPKEYLGM--LQYKREDEAKLIQNLILDL 1382
            KLQ +  T    I K  D        E L M     K   E KL++  I DL
Sbjct: 968  KLQLEKVTAEAKIKKLED--------EILVMDDQNNKLSKERKLLEERISDL 1011


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score =  607 bits (1565), Expect = e-173
 Identities = 437/1418 (30%), Positives = 717/1418 (50%), Gaps = 137/1418 (9%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            VW+P  ++ +++A I ++   GD+V+  L+E+G ++  +V  + +  + NP       D+
Sbjct: 36   VWVPSEKQGFEAASIKEEK--GDEVVVELVENGKKV--TVGKDDIQKM-NPPKFSKVEDM 90

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 91   AELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHE 149

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----- 187
            M PHI+A+A+ AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S        
Sbjct: 150  MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209

Query: 188  --AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKS 245
                +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ TYLLEKS
Sbjct: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269

Query: 246  RVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTV-IEGVNDRAEMV 304
            R + Q+ +ER +HIFY + A A++     L L      NYT +    V I    D     
Sbjct: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQ 327

Query: 305  ETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLGL 364
            ET +   ++GF E+ Q+ + K+++++L LGN+      N   +   D++  +  C L+G+
Sbjct: 328  ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387

Query: 365  ESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQFS 424
                  + +   +I    + V K  T+ QA  A +ALAK  Y  LF +I+ R+N+AL  +
Sbjct: 388  NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 447

Query: 425  GKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWT 483
             +Q  +F+G+LDI GFE F+VNSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W 
Sbjct: 448  HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507

Query: 484  LIDF-YDNQPVIDLIEA---KMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
             IDF  D QP I+LIE      G+L LLDEEC  P  TD+++++KL       +P F+KP
Sbjct: 508  FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE-QGSHPKFQKP 566

Query: 540  RM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQE-NPTP 596
            +     T F I H+A KV+Y    +L KN D + D +  +L AS     A+ +++ +   
Sbjct: 567  KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626

Query: 597  PSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEK 656
                 + +T  S     K     FR TVG  ++  L  LM TL  TTP++VRCI PN EK
Sbjct: 627  GLDQMAKMTESSLPSASKTKKGMFR-TVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685

Query: 657  LPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKKE 715
               + D+  +++QLR  GVLE IRI  Q +P+R  + EF  RY IL        F D K+
Sbjct: 686  RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQ 745

Query: 716  VCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKK 775
             C +++  L  D N Y+ G++KIFFR G +A+LE+ R  K+    +  Q   RG+L RK 
Sbjct: 746  ACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKA 805

Query: 776  FLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMAT- 834
            F + ++           Q T  K              +IQ++C  YL    +Q  R+ T 
Sbjct: 806  FAKRQQ-----------QLTAMK--------------VIQRNCAAYLKLRNWQWWRLFTK 840

Query: 835  ------ITMQ-------------AYSRGFLARRRYRKMLEEHKAV-----ILQKYARA-- 868
                  +T Q                R   A    +++ ++H  +     +LQ+  +A  
Sbjct: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900

Query: 869  -WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQ 927
               A      +R      +L   +  ++ +LE++      L  +   +A       E+++
Sbjct: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960

Query: 928  KLEAELEKAATHRRNYEEKGKRYRDAV---EEKLAKLQKHNSELETQKEQIQLKLQEKTE 984
            + EA  +K    +   E K K+  D +   +++  KL K    LE +   +   L E+ E
Sbjct: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020

Query: 985  ------ELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLKEEIKA 1035
                  +LK K +++  +L   ++KEE+ R  LEK     E    D+ +QI  L+ +I  
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080

Query: 1036 LKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK----H 1091
            L   KMQL    E        L  E+A+ +  +K I E E  I  LQ + +D E+     
Sbjct: 1081 L---KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARNK 1136

Query: 1092 VQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVL 1151
             + QKR++ E++  +  +L ++ D    +  L  +       + E+    + L + TR  
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAK------REQEVTVLKKALDEETRSH 1190

Query: 1152 ESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMI 1211
            E+  Q  +  + + +E        L++++   ++     +   +++  E   L  E  ++
Sbjct: 1191 EAQVQEMRQKHAQAVE-------ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243

Query: 1212 PDFKQQI----SELEKQKQDLEIR----------LNEQAEKMKGKLEELSNQLHRSQ--- 1254
               KQ++     +LE Q Q+L+ +          LN++  K++ ++E ++  L+ ++   
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA 1303

Query: 1255 ----EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFR 1307
                ++  +    L+   E+    T++K  +  K+++++E  + L+ Q + E E K N  
Sbjct: 1304 IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLE 1363

Query: 1308 QEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
            +  S L ++  D +++L      ++ L++  K   K I
Sbjct: 1364 RHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1401



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 107/479 (22%), Positives = 221/479 (46%), Gaps = 60/479 (12%)

Query: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953
            L K  +   KEN  L  +L  L   +     K +KLEA++++  +   +    G+R R  
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD----GERARAE 1277

Query: 954  VEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDD---VQKEERQRML 1010
            + +K+ KLQ   +E+E+    +  + + K  +L + + +L+ QL D    +Q+E RQ++ 
Sbjct: 1278 LNDKVHKLQ---NEVESVTGMLN-EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL- 1332

Query: 1011 LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKT 1070
               +   K +  E++  SL++++    DE+M+ +  +E  H+++  ++     LS   K 
Sbjct: 1333 ---NVSTKLRQLEEERNSLQDQL----DEEMEAKQNLE-RHISTLNIQ-----LSDSKKK 1379

Query: 1071 ISEFEKEIELLQAQKIDVEKHVQSQKREMREKMS-----EITKQLLESYDIEDV-----R 1120
            + +F   +E L+  K   +K +++  ++  EK +     E TK  L+  +++D+      
Sbjct: 1380 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-ELDDLVVDLDN 1438

Query: 1121 SRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEI 1180
             R  V +LE      +   A E      + + S +  ++D  E E      K + L++ +
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEE------KNISSKYADERDRAEAEAREKETKALSLARAL 1492

Query: 1181 NHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMK 1240
                +   E    N+ ++ E+  L S      D  + + ELEK K+ LE     Q E+MK
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSK---DDVGKNVHELEKSKRALET----QMEEMK 1545

Query: 1241 GKLEELSNQLHRSQEEE-----------GTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS 1289
             +LEEL ++L  +++ +           G   + L+A++E + +++ +L  ++ E +   
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605

Query: 1290 DHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKA 1348
            +  +KQ    +  K     +   L L+     +  +   + ++KLQ Q+K   + +  A
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 94/482 (19%), Positives = 208/482 (43%), Gaps = 51/482 (10%)

Query: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGD-VEKIQK-L 929
            +R+F  +     NI   Y  +R + + E + KE   L        AL A + +E+  K L
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509

Query: 930  EAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKE- 988
            +AE+E   + +           D V + + +L+K    LETQ E+++ +L+E  +EL+  
Sbjct: 1510 KAEMEDLVSSK-----------DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558

Query: 989  ---------KMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDE 1039
                      M  L  Q   D+Q  + Q     +  + +  +YE +++  +++       
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618

Query: 1040 KMQLQHLVEGEHVTSD----GLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
            K +L+  ++   + +D    G +  + +L K    + +F++E+E  +A + ++    +  
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +++ +   +++ +   +    E  R +  +E  E   E          L+   R LE+  
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738

Query: 1156 QSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDI---NESIRHEVTRLTSENM 1209
               ++  E+E   +EA++ +V   +Q+   L      E      NES R ++ R      
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN---- 1794

Query: 1210 MIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269
                 K+  S+L + +  ++ +       ++ K+ +L  Q+ +   E+    K+L+ +++
Sbjct: 1795 -----KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849

Query: 1270 ------IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEE 1323
                  +  +++ K+ ++ +E  E  +   KQ + + E      +E+ R+    R L+ E
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE---EAEEESQRINANRRKLQRE 1906

Query: 1324 LD 1325
            LD
Sbjct: 1907 LD 1908



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 152/726 (20%), Positives = 287/726 (39%), Gaps = 91/726 (12%)

Query: 707  ELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKH 766
            ++  + K+E  +  L RL  +  Q      KI    G ++ L++  LD  R +    +K 
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE-DLDSERAARNKAEKQ 1140

Query: 767  MRGWLQR----KKFLRERRAALIIQQYFRGQQTVRKAITAVALKE------AWAAIIIQK 816
             R   +     K  L +   +   QQ  R ++     +   AL E      A    + QK
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200

Query: 817  HCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQ 876
            H          Q +   T  ++ + R      + ++ LE+  A +  +      A++  +
Sbjct: 1201 HA---------QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1251

Query: 877  SIRRFVLNIQLTYRVQRLQKKLEDQ-------NKENHGL---VEKLTSLAALRAGDVEKI 926
              ++     +L  +VQ LQ K  D        N + H L   VE +T +     G   K+
Sbjct: 1252 HKKK-----KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306

Query: 927  QKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQ-KEQIQLK--LQEKT 983
             K  A L       +   ++  R +  V  KL +L++  + L+ Q  E+++ K  L+   
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366

Query: 984  EELKEKMDNLTKQLFD---DVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEK 1040
              L  ++ +  K+L D    V+  E  +   +K  E  TQ YE++  +  +    L+  K
Sbjct: 1367 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK----LEKTK 1422

Query: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100
             +LQ  ++   V  D  +  V+ L K+ +   +   E + + ++  D     +++ RE  
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482

Query: 1101 EKMSEITKQLLESYDIEDVRSRLS------VEDLEHLNED-GELWFAYEGLKKATRVLES 1153
             K   + + L E+ + ++   R +      +EDL    +D G+     E  K+A      
Sbjct: 1483 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542

Query: 1154 HFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREE----NDINESIRHEVTRLTSE-N 1208
              ++Q +  E E++A     + L   +  L+  F  +    ++ NE  R ++ R   E  
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1602

Query: 1209 MMIPDFKQQIS-------ELEKQKQDLEIRLN------EQAEKMKGKLEELSNQLHRSQE 1255
              + D ++Q +       +LE   +DLE++ +      E+A K   KL+       R  E
Sbjct: 1603 TELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELE 1662

Query: 1256 EEGTQRKALEA---QNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASR 1312
            +    R  + A   +NE   K  E  + ++QE   A++  +KQ + E E           
Sbjct: 1663 DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE----------- 1711

Query: 1313 LTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGK-ANDVHSSSGPKEYLGMLQYKREDE 1371
                  +L EEL         LQD+ + L   I +   ++    G  E +     K   +
Sbjct: 1712 ------ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 1765

Query: 1372 AKLIQN 1377
            A+ + N
Sbjct: 1766 AEQLSN 1771



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)

Query: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
            +Q  E++ ++ +L+ +  E+ +K + +L+EL  +  +  EE+   ++ L+A+ E++ + +
Sbjct: 849  RQEEEMQAKEDELQ-KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907

Query: 1276 E---KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIK 1332
            E   +L  K QE++E    ++ + E E +     + E  ++  +  DLEE+L+ ++   +
Sbjct: 908  EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967

Query: 1333 KLQDQVKTLSKTIGKANDVHSSSGPKEYLGM--LQYKREDEAKLIQNLILDL 1382
            KLQ +  T    I K  D        E L M     K   E KL++  I DL
Sbjct: 968  KLQLEKVTAEAKIKKLED--------EILVMDDQNNKLSKERKLLEERISDL 1011


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score =  606 bits (1562), Expect = e-173
 Identities = 428/1364 (31%), Positives = 682/1364 (50%), Gaps = 114/1364 (8%)

Query: 52   VNPESLPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPY 111
            V PE +  + NP       D+  L++L+EPAVL+NL+ R+  S +IYTYSG+  V +NPY
Sbjct: 72   VKPEDVYAM-NPPKFDRIEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPY 129

Query: 112  KQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSA 171
            K LP+Y   ++  Y G+   +  PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ 
Sbjct: 130  KWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNT 189

Query: 172  RYAMRYFATVSKSGSNAH---------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYT 222
            +  ++YFAT++ +G  A          +ED+++++NP+ EA GNAKT RNDNSSRFGK+ 
Sbjct: 190  KRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFI 249

Query: 223  EISFDEQNQIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEE 282
             I F    ++  A++ TYLLEKSRV FQ + ER+YHIFYQ+ ++ ++ E   L L +   
Sbjct: 250  RIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIELLLITTNP 308

Query: 283  FNYTRMG-GNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAV 341
            ++Y  +  G  ++  ++D  E++ T     +LGF  + +  ++K+  A++H GN++    
Sbjct: 309  YDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQK 368

Query: 342  GNERSSVSEDDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDAL 401
              E  +  +          L+GL S  + + LC  ++   +E V K  T  Q  +A +AL
Sbjct: 369  QREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNAL 428

Query: 402  AKKIYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQ 461
            +K +Y  LF ++V RINQ L     +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ
Sbjct: 429  SKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQ 488

Query: 462  QFNMHVFKLEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDEN 520
             FN H+F LEQEEY KE I WT IDF  D    I+LIE  MGI  +L+EEC+ P  TD +
Sbjct: 489  FFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTS 548

Query: 521  WLQKLYNNFVNRNPLFEKPRM----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVE 576
            +  KLY+  + ++  F+KP++    +   F + H+A  V+Y   G+LEKN+D + + +V 
Sbjct: 549  FKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVG 608

Query: 577  ILRASKFHLCANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLM 636
            + + S   L A+ +    T  +  G        K+V K     F+ TV + FR +L  LM
Sbjct: 609  LYQKSSNRLLAHLYATFATADADSGK-------KKVAKKKGSSFQ-TVSALFRENLNKLM 660

Query: 637  ETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFY 696
              L  T PH+VRCI PN+ K P   +   ++ QLR  GVLE IRI  + +P+R  Y +F 
Sbjct: 661  SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK 720

Query: 697  SRYGILMTK--QELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLD 754
             RY +L      E  F D K+ C+ +L  +  D  QY+FG TK+FF+AG +  LE++R D
Sbjct: 721  QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD 780

Query: 755  KLRQSCVMVQKHMRGWLQR---KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAA 811
            +L +     Q   RG+L R   +K ++ R +   IQ   R    V+           W  
Sbjct: 781  RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVK--------HWPWMK 832

Query: 812  IIIQKHCRGYLVRSLYQLIRMATI--TMQAYSRGFLARRRYRKMLEEHKAVILQKYARAW 869
            +  +      L++S      MAT+    Q            RK LEE    ++Q+     
Sbjct: 833  LFFKIK---PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQ 889

Query: 870  L-----------ARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAAL 918
            L           A  R   + +     QL  +++ + ++ ED+ + N  L  K   L   
Sbjct: 890  LQVQAESENLLDAEERCDQLIK--AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 947

Query: 919  RAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQI 975
             +   + I  LE  L K    +   E K K   +    ++E +AKL +    L+   +Q 
Sbjct: 948  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 1007

Query: 976  QLKLQEKTEEL------KEKMDNLTKQLFDDVQKEERQRMLLEKS-----FELKTQ---- 1020
               LQ + +++      K K++   + L   +++E++ R+ LE++      +LK      
Sbjct: 1008 LDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067

Query: 1021 -DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079
             D E   Q L E +K    E  QLQ  VE E       + ++  L  +   I E E+EIE
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQAR---IEELEEEIE 1124

Query: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE----------DLE 1129
              +A +   EK    Q+ +   ++ E++++L E+  +   +  L+ +          DLE
Sbjct: 1125 AERATRAKTEK----QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 1180

Query: 1130 HLNEDGELWFAYEGLKKATRVLE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQ 1184
                  E   A    K A  V E      + Q  K   EKE      ++  LS  +  + 
Sbjct: 1181 EATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 1240

Query: 1185 KLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244
            K       I  ++  +++    +N    + ++ +SEL  QK  L+    E + +++ K E
Sbjct: 1241 KSKANLEKICRTLEDQLSEARGKN---EEIQRSLSELTTQKSRLQTEAGELSRQLEEK-E 1296

Query: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304
             + +QL RS++    Q + L+ Q E   K K  L   +Q  +   D L++Q+E E E K 
Sbjct: 1297 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKA 1356

Query: 1305 NFRQEASRLTLE------------NRDLEEELDMKDRVIKKLQD 1336
              ++  S+   E             +  EE  + K ++ ++LQD
Sbjct: 1357 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1400



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 140/643 (21%), Positives = 275/643 (42%), Gaps = 129/643 (20%)

Query: 828  QLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQL 887
            +L ++ T T QA  RGFL R  ++KM++  +++   +Y       R F +++ +   ++L
Sbjct: 781  RLAKLITRT-QAVCRGFLMRVEFQKMVQRRESIFCIQY-----NIRSFMNVKHWPW-MKL 833

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK- 946
             ++++ L K  E + +           +A ++    E+ QK + EL K+   R+  EEK 
Sbjct: 834  FFKIKPLLKSAETEKE-----------MATMK----EEFQKTKDELAKSEAKRKELEEKL 878

Query: 947  ---------GKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL----------- 986
                      +    A  E L   ++   +L   K Q++ K++E TE             
Sbjct: 879  VTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELT 938

Query: 987  --KEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLKEEIKALKDEKM 1041
              K K+++   +L  D+   E     +EK   + E K ++  +++  L E I  L  EK 
Sbjct: 939  AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKK 998

Query: 1042 QLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ-------KIDVEKHVQS 1094
             LQ   E      D L+AE  +++   KT S+ E+++E L++        ++D+E++ + 
Sbjct: 999  ALQ---EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055

Query: 1095 QKREMR---------EKMSEITKQLLESYDIEDVRSRLSVED-----LEHLNEDGELWFA 1140
             + +++         E   +   + L+  D E  + +  VED     L+   +  EL   
Sbjct: 1056 LEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQAR 1115

Query: 1141 YEGLK---KATRVLESHFQSQKDCYEKEIEALNFK------VVHLSQEINHLQ--KLFRE 1189
             E L+   +A R   +  + Q+  Y +E+E L+ +      V     E+N  +  +  + 
Sbjct: 1116 IEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKL 1175

Query: 1190 ENDINE-SIRHE--VTRLTSENM-MIPDFKQQISELEKQKQDLEIRLN------------ 1233
              D+ E +++HE  V  L  ++   + +  +QI  L++ KQ LE   +            
Sbjct: 1176 RRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS 1235

Query: 1234 -EQAEKMKGKLEEL--------------SNQLHRSQEEEGTQRKALEAQ-NEI--HTKEK 1275
             E   K K  LE++              + ++ RS  E  TQ+  L+ +  E+    +EK
Sbjct: 1236 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEK 1295

Query: 1276 EKLIDKIQEMQEA----SDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVI 1331
            E ++ ++   ++A    ++ LK+Q E E++ K       + L    +    + D+     
Sbjct: 1296 ESIVSQLSRSKQAFTQQTEELKRQLEEENKAK-------NALAHALQSSRHDCDLLREQY 1348

Query: 1332 KKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRE-DEAK 1373
            ++ Q+    L + + KAN   +    K     +Q   E +EAK
Sbjct: 1349 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1391



 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 111/534 (20%), Positives = 236/534 (44%), Gaps = 63/534 (11%)

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
            T + + L+++LE++NK  + L   L S      L     E+ Q+ +AEL++A        
Sbjct: 1310 TQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEV 1369

Query: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
            A  R  YE    +  + +EE   KL +   + E Q E +  K     E+ K+++    + 
Sbjct: 1370 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVED 1428

Query: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
            L  DV++       L+K           ++ K ++ + ++++  +E ++L  E  +L++ 
Sbjct: 1429 LMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA 1488

Query: 1047 VEG-----EHVTSDG--LKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
             E      E V  +   L+ E+A L++Q+    KTI E EK  + ++ +K D++  ++  
Sbjct: 1489 YEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEA 1548

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +  +  + ++I +  LE   +  V+S +   D +   +D E+       ++    ++S  
Sbjct: 1549 EAALEHEEAKILRIQLE---LTQVKSEI---DRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602

Query: 1156 QSQKDCYEKEIEALNFKVVHLSQEINHLQ-KLFREENDINESIRHEVTRLTSENMMIPDF 1214
             ++        EA+  K   +  ++N ++ +L        E+++H    L S    + D 
Sbjct: 1603 DAE---VRSRNEAIRLKK-KMEGDLNEIEIQLSHANRQAAETLKH----LRSVQGQLKDT 1654

Query: 1215 KQQISELEKQKQDLEIRL---NEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE-- 1269
            +  + +  + ++DL+ +L     +A  ++ ++EEL   L +++       + L   NE  
Sbjct: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714

Query: 1270 --IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMK 1327
              +HT +   LI   ++++     L+ + E  S    N  ++A +   +   + EEL  +
Sbjct: 1715 QLLHT-QNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKE 1773

Query: 1328 -------DRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
                   +R+ K L+  VK L   + +A  +    G K+   +    RE E +L
Sbjct: 1774 QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFEL 1827



 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 119/509 (23%), Positives = 226/509 (44%), Gaps = 56/509 (11%)

Query: 849  RYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGL 908
            + R+ LEE  A +  +   A L ++   S+      I     +QR+++KLE +  E    
Sbjct: 1174 KLRRDLEE--ATLQHEAMVAALRKKHADSVAELGEQID---NLQRVKQKLEKEKSEFKLE 1228

Query: 909  VEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSEL 968
            ++ L+S        +E + K +A LEK     R  E++    R   EE    +Q+  SEL
Sbjct: 1229 IDDLSS-------SMESVSKSKANLEKIC---RTLEDQLSEARGKNEE----IQRSLSEL 1274

Query: 969  ETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQS 1028
             TQK ++Q +  E + +L+EK +++  QL    Q           +F  +T++ ++Q++ 
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEK-ESIVSQLSRSKQ-----------AFTQQTEELKRQLEE 1322

Query: 1029 LKEEIKALKDEKMQLQH---LVEGEHVTSDGLKAEVAR-LSKQVKTISEFEKEIE---LL 1081
              +   AL       +H   L+  ++      KAE+ R LSK    ++++  + E   + 
Sbjct: 1323 ENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ 1382

Query: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDL-EHLNEDGELWFA 1140
            + ++++  K   +Q+ +  E+  E       S +    R +  VEDL   +     L  A
Sbjct: 1383 RTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 1442

Query: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
             +  ++    + + ++++ +  + E+EA   +   LS E+  L+  + E  D  E+++ E
Sbjct: 1443 LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 1502

Query: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
               L  E   I D  +QI+E  K   +LE +  +Q E  K  ++    +   + E E  +
Sbjct: 1503 NKNLEQE---IADLTEQIAENGKTIHELE-KSRKQIELEKADIQLALEEAEAALEHE--E 1556

Query: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
             K L  Q E+ T+ K ++  KI E  E  + LK+ ++   E         S L  E R  
Sbjct: 1557 AKILRIQLEL-TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETM------QSALDAEVRSR 1609

Query: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKAN 1349
             E + +K    KK++  +  +   +  AN
Sbjct: 1610 NEAIRLK----KKMEGDLNEIEIQLSHAN 1634



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 101/517 (19%), Positives = 218/517 (42%), Gaps = 51/517 (9%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    +  A    + +  +S+   +  ++  Y  +    +LE   +EN 
Sbjct: 1447 QRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY--EEALDQLETVKRENK 1504

Query: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
             L +++  L    A + + I +LE   ++    + + +   +    A+E + AK+ +   
Sbjct: 1505 NLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL 1564

Query: 967  ELETQKEQIQLKLQEKTEELKEKMDNLTKQL------FDDVQKEERQRMLLEKSFELKTQ 1020
            EL   K +I  K+ EK EE+++   N  + +       D   +   + + L+K  E    
Sbjct: 1565 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 1624

Query: 1021 DYEKQ-----------IQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069
            + E Q           ++ L+     LKD ++ L   + G+    + LK ++A + ++  
Sbjct: 1625 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQ----EDLKEQLAIVERRAN 1680

Query: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128
             +   + E+E L+A     E+  +  ++E+ +    +  QLL + +   + ++  +E DL
Sbjct: 1681 LL---QAEVEELRATLEQTERARKLAEQELLDSNERV--QLLHTQNTSLIHTKKKLETDL 1735

Query: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFR 1188
              L  +         ++ A+R   +  +  K    K I         L +E +    L R
Sbjct: 1736 MQLQSE---------VEDASRDARNAEEKAK----KAITDAAMMAEELKKEQDTSAHLER 1782

Query: 1189 EENDINESIRHEVTRL-TSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELS 1247
             + ++ ++++    RL  +E + +   K+QI +LE + ++LE  L  + +K    ++ L 
Sbjct: 1783 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842

Query: 1248 NQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFR 1307
                R +E        L  Q+E   K   +L D + ++Q      K+Q E   E      
Sbjct: 1843 KYERRVKE--------LTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL 1894

Query: 1308 QEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKT 1344
             +  +   E  + EE  D+ +  + KL+ + +  + +
Sbjct: 1895 TKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1931



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 91/382 (23%), Positives = 181/382 (47%), Gaps = 57/382 (14%)

Query: 1017 LKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEK 1076
            LK+ + EK++ ++KEE +  KDE      L + E        A+   L +++ T+ + + 
Sbjct: 841  LKSAETEKEMATMKEEFQKTKDE------LAKSE--------AKRKELEEKLVTLVQEKN 886

Query: 1077 EIEL-LQAQK---IDVEKHVQS---QKREMREKMSEITKQLLESYDIEDVRSRLSVEDLE 1129
            +++L +QA+    +D E+        K ++  K+ E+T++   + D E++ + L+ +  +
Sbjct: 887  DLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTER---AEDEEEINAELTAKKRK 943

Query: 1130 HLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQ----K 1185
              +E  EL       KK    LE          EKE  A   KV +L++E++ L     K
Sbjct: 944  LEDECSEL-------KKDIDDLELTLAK----VEKEKHATENKVKNLTEELSGLDETIAK 992

Query: 1186 LFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEE 1245
            L RE+  + E+ +  +  L +E   +    +  S+LE+Q +DLE  L EQ +K++  LE 
Sbjct: 993  LTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL-EQEKKLRVDLER 1051

Query: 1246 LSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCN 1305
               +L      EG  + A E+  ++   +K++L +++++       L+ + E E  +   
Sbjct: 1052 NKRKL------EGDLKLAQESILDLEN-DKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQ 1104

Query: 1306 FRQEASRLTLENRDLEEELDMKDRVIKKLQDQ-------VKTLSKTIGKANDVHSSS--- 1355
            F+++   L     +LEEE++ +     K + Q       ++ LS+ + +A  V S+    
Sbjct: 1105 FQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIEL 1164

Query: 1356 GPKEYLGMLQYKREDEAKLIQN 1377
              K     L+ +R+ E   +Q+
Sbjct: 1165 NKKREAEFLKLRRDLEEATLQH 1186



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 68/285 (23%), Positives = 118/285 (41%), Gaps = 82/285 (28%)

Query: 1136 ELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINE 1195
            +L+F  + L K+    E    + K+ ++K  + L        +    L  L +E+ND+  
Sbjct: 832  KLFFKIKPLLKSAET-EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL 890

Query: 1196 SIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQE 1255
             ++ E     SEN++  D +++  +L K K  LE ++ E  E+ + + EE++ +L     
Sbjct: 891  QVQAE-----SENLL--DAEERCDQLIKAKFQLEAKIKEVTERAEDE-EEINAEL----- 937

Query: 1256 EEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHL--------KKQFETESEVKCNFR 1307
                            T +K KL D+  E+++  D L        K++  TE++VK    
Sbjct: 938  ----------------TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK---- 977

Query: 1308 QEASRLTLENRDLEEELDMKDRVIKKL---------------------QDQVKTLSKTIG 1346
                       +L EEL   D  I KL                     +D+V +L+KT  
Sbjct: 978  -----------NLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 1026

Query: 1347 K----ANDVHSSSGPKEYLGM----LQYKREDEAKLIQNLILDLK 1383
            K      D+ SS   ++ L +     + K E + KL Q  ILDL+
Sbjct: 1027 KLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLE 1071


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score =  604 bits (1558), Expect = e-172
 Identities = 437/1425 (30%), Positives = 717/1425 (50%), Gaps = 144/1425 (10%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            VW+P  ++ +++A I ++   GD+V+  L+E+G ++  +V  + +  + NP       D+
Sbjct: 36   VWVPSEKQGFEAASIKEEK--GDEVVVELVENGKKV--TVGKDDIQKM-NPPKFSKVEDM 90

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 91   AELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHE 149

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----- 187
            M PHI+A+A+ AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S        
Sbjct: 150  MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209

Query: 188  ---------AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
                       +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ 
Sbjct: 210  ITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 269

Query: 239  TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTV-IEGV 297
            TYLLEKSR + Q+ +ER +HIFY + A A++     L L      NYT +    V I   
Sbjct: 270  TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAA 327

Query: 298  NDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKV 357
             D     ET +   ++GF E+ Q+ + K+++++L LGN+      N   +   D++  + 
Sbjct: 328  QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387

Query: 358  FCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERI 417
             C L+G+      + +   +I    + V K  T+ QA  A +ALAK  Y  LF +I+ R+
Sbjct: 388  VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447

Query: 418  NQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 476
            N+AL  + +Q  +F+G+LDI GFE F+VNSFEQ CINY NEKLQQ FN  +F LEQEEY 
Sbjct: 448  NKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQ 507

Query: 477  KEDIPWTLIDF-YDNQPVIDLIEA---KMGILELLDEECLLPHGTDENWLQKLYNNFVNR 532
            +E I W  IDF  D QP I+LIE      G+L LLDEEC  P  TD+++++KL       
Sbjct: 508  REGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE-QGS 566

Query: 533  NPLFEKPRM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFF 590
            +P F+KP+     T F I H+A KV+Y    +L KN D + D +  +L AS     A+ +
Sbjct: 567  HPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626

Query: 591  QE-NPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRC 649
            ++ +        + +T  S     K     FR TVG  ++  L  LM TL  TTP++VRC
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFR-TVGQLYKEQLGKLMTTLRNTTPNFVRC 685

Query: 650  IKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-EL 708
            I PN EK   + D+  +++QLR  GVLE IRI  Q +P+R  + EF  RY IL       
Sbjct: 686  IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 745

Query: 709  SFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMR 768
             F D K+ C +++  L  D N Y+ G++KIFFR G +A+LE+ R  K+    +  Q   R
Sbjct: 746  GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 805

Query: 769  GWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQ 828
            G+L RK F + ++           Q T  K              +IQ++C  YL    +Q
Sbjct: 806  GYLARKAFAKRQQ-----------QLTAMK--------------VIQRNCAAYLKLRNWQ 840

Query: 829  LIRMAT-------ITMQ-------------AYSRGFLARRRYRKMLEEHKAV-----ILQ 863
              R+ T       +T Q                R   A    +++ ++H  +     +LQ
Sbjct: 841  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900

Query: 864  KYARA---WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRA 920
            +  +A     A      +R      +L   +  ++ +LE++      L  +   +A    
Sbjct: 901  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 921  GDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAV---EEKLAKLQKHNSELETQKEQIQL 977
               E++++ EA  +K    +   E K K+  D +   +++  KL K    LE +   +  
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 978  KLQEKTE------ELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQS 1028
             L E+ E      +LK K +++  +L   ++KEE+ R  LEK     E    D+ +QI  
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080

Query: 1029 LKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDV 1088
            L+ +I  L   KMQL    E        L  E+A+ +  +K I E E  I  LQ + +D 
Sbjct: 1081 LQAQIAEL---KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDS 1136

Query: 1089 EK----HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGL 1144
            E+      + QKR++ E++  +  +L ++ D    +  L  +       + E+    + L
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK------REQEVTVLKKAL 1190

Query: 1145 KKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRL 1204
             + TR  E+  Q  +  + + +E        L++++   ++     +   +++  E   L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVE-------ELTEQLEQFKRAKANLDKNKQTLEKENADL 1243

Query: 1205 TSENMMIPDFKQQI----SELEKQKQDLEIR----------LNEQAEKMKGKLEELSNQL 1250
              E  ++   KQ++     +LE Q Q+L+ +          LN++  K++ ++E ++  L
Sbjct: 1244 AGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1303

Query: 1251 HRSQ-------EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDHLKKQFETES 1300
            + ++       ++  +    L+   E+    T++K  +  K+++++E  + L+ Q + E 
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363

Query: 1301 EVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
            E K N  +  S L ++  D +++L      ++ L++  K   K I
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1408



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 97/507 (19%), Positives = 217/507 (42%), Gaps = 51/507 (10%)

Query: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGD-VEKIQK-L 929
            +R+F  +     NI   Y  +R + + E + KE   L        AL A + +E+  K L
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1516

Query: 930  EAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKE- 988
            +AE+E   + +           D V + + +L+K    LETQ E+++ +L+E  +EL+  
Sbjct: 1517 KAEMEDLVSSK-----------DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565

Query: 989  ---------KMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDE 1039
                      M  L  Q   D+Q  + Q     +  + +  +YE +++  +++       
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625

Query: 1040 KMQLQHLVEGEHVTSD----GLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
            K +L+  ++   + +D    G +  + +L K    + +F++E+E  +A + ++    +  
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +++ +   +++ +   +    E  R +  +E  E   E          L+   R LE+  
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745

Query: 1156 QSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDI---NESIRHEVTRLTSENM 1209
               ++  E+E   +EA++ +V   +Q+   L      E      NES R ++ R      
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN---- 1801

Query: 1210 MIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269
                 K+  S+L + +  ++ +       ++ K+ +L  Q+ +   E+    K+L+ +++
Sbjct: 1802 -----KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856

Query: 1270 ------IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEE 1323
                  +  +++ K+ ++ +E  E  +   KQ + + E      +E+ R+    R L+ E
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE---EAEEESQRINANRRKLQRE 1913

Query: 1324 LDMKDRVIKKLQDQVKTLSKTIGKAND 1350
            LD      + +  +V  L   + + N+
Sbjct: 1914 LDEATESNEAMGREVNALKSKLRRGNE 1940



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 106/476 (22%), Positives = 205/476 (43%), Gaps = 77/476 (16%)

Query: 886  QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945
            QL      LQ +L+++ +    L   +++L    +   +K+Q   + +E     ++ +++
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406

Query: 946  KGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEE 1005
            + +      EEK A   K         E+ + +LQ++ ++L   +DN  +QL  +++K++
Sbjct: 1407 EIENLTQQYEEKAAAYDK--------LEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQ 1457

Query: 1006 R---QRMLLEKSFELKTQDY--EKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAE 1060
            R   Q +  EK+   K  D     + ++ ++E KAL   +  L+  +E         K E
Sbjct: 1458 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR-ALEEALEA--------KEE 1508

Query: 1061 VARLSKQVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLESYDIE 1117
            + R +K +K       E+E L + K DV K+V   +  KR +  +M E+  QL E     
Sbjct: 1509 LERTNKMLKA------EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE----- 1557

Query: 1118 DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLS 1177
                   +ED     ED +L             LE + Q+ K  +E++++A + +     
Sbjct: 1558 -------LEDELQATEDAKL------------RLEVNMQALKGQFERDLQARDEQNEEKR 1598

Query: 1178 QEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAE 1237
            +++   ++L   E ++ +  +       ++  +  D K    +LE Q  D  I+  E+A 
Sbjct: 1599 RQLQ--RQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQ-ADSAIKGREEAI 1651

Query: 1238 KMKGKLEELSNQLHRSQEEEGTQRKALEA---QNEIHTKEKEKLIDKIQEMQEASDHLKK 1294
            K   KL+       R  E+    R  + A   +NE   K  E  + ++QE   A++  +K
Sbjct: 1652 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711

Query: 1295 QFETESEVKCN-----------FRQEASRLTLENRDLEEELDMKDRVIKKLQDQVK 1339
            Q + E E                + E  RL      LEEEL+ +   ++ + D+V+
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1767



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)

Query: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
            +Q  E++ ++ +L+ +  E+ +K + +L+EL  +  +  EE+   ++ L+A+ E++ + +
Sbjct: 856  RQEEEMQAKEDELQ-KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 914

Query: 1276 E---KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIK 1332
            E   +L  K QE++E    ++ + E E +     + E  ++  +  DLEE+L+ ++   +
Sbjct: 915  EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974

Query: 1333 KLQDQVKTLSKTIGKANDVHSSSGPKEYLGM--LQYKREDEAKLIQNLILDL 1382
            KLQ +  T    I K  D        E L M     K   E KL++  I DL
Sbjct: 975  KLQLEKVTAEAKIKKLED--------EILVMDDQNNKLSKERKLLEERISDL 1018


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score =  604 bits (1558), Expect = e-172
 Identities = 437/1425 (30%), Positives = 717/1425 (50%), Gaps = 144/1425 (10%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            VW+P  ++ +++A I ++   GD+V+  L+E+G ++  +V  + +  + NP       D+
Sbjct: 36   VWVPSEKQGFEAASIKEEK--GDEVVVELVENGKKV--TVGKDDIQKM-NPPKFSKVEDM 90

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 91   AELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHE 149

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----- 187
            M PHI+A+A+ AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S        
Sbjct: 150  MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209

Query: 188  ---------AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
                       +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ 
Sbjct: 210  ITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 269

Query: 239  TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTV-IEGV 297
            TYLLEKSR + Q+ +ER +HIFY + A A++     L L      NYT +    V I   
Sbjct: 270  TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAA 327

Query: 298  NDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKV 357
             D     ET +   ++GF E+ Q+ + K+++++L LGN+      N   +   D++  + 
Sbjct: 328  QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387

Query: 358  FCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERI 417
             C L+G+      + +   +I    + V K  T+ QA  A +ALAK  Y  LF +I+ R+
Sbjct: 388  VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447

Query: 418  NQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 476
            N+AL  + +Q  +F+G+LDI GFE F+VNSFEQ CINY NEKLQQ FN  +F LEQEEY 
Sbjct: 448  NKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQ 507

Query: 477  KEDIPWTLIDF-YDNQPVIDLIEA---KMGILELLDEECLLPHGTDENWLQKLYNNFVNR 532
            +E I W  IDF  D QP I+LIE      G+L LLDEEC  P  TD+++++KL       
Sbjct: 508  REGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE-QGS 566

Query: 533  NPLFEKPRM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFF 590
            +P F+KP+     T F I H+A KV+Y    +L KN D + D +  +L AS     A+ +
Sbjct: 567  HPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626

Query: 591  QE-NPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRC 649
            ++ +        + +T  S     K     FR TVG  ++  L  LM TL  TTP++VRC
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFR-TVGQLYKEQLGKLMTTLRNTTPNFVRC 685

Query: 650  IKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-EL 708
            I PN EK   + D+  +++QLR  GVLE IRI  Q +P+R  + EF  RY IL       
Sbjct: 686  IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 745

Query: 709  SFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMR 768
             F D K+ C +++  L  D N Y+ G++KIFFR G +A+LE+ R  K+    +  Q   R
Sbjct: 746  GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 805

Query: 769  GWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQ 828
            G+L RK F + ++           Q T  K              +IQ++C  YL    +Q
Sbjct: 806  GYLARKAFAKRQQ-----------QLTAMK--------------VIQRNCAAYLKLRNWQ 840

Query: 829  LIRMAT-------ITMQ-------------AYSRGFLARRRYRKMLEEHKAV-----ILQ 863
              R+ T       +T Q                R   A    +++ ++H  +     +LQ
Sbjct: 841  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900

Query: 864  KYARA---WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRA 920
            +  +A     A      +R      +L   +  ++ +LE++      L  +   +A    
Sbjct: 901  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 921  GDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAV---EEKLAKLQKHNSELETQKEQIQL 977
               E++++ EA  +K    +   E K K+  D +   +++  KL K    LE +   +  
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 978  KLQEKTE------ELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQS 1028
             L E+ E      +LK K +++  +L   ++KEE+ R  LEK     E    D+ +QI  
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080

Query: 1029 LKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDV 1088
            L+ +I  L   KMQL    E        L  E+A+ +  +K I E E  I  LQ + +D 
Sbjct: 1081 LQAQIAEL---KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDS 1136

Query: 1089 EK----HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGL 1144
            E+      + QKR++ E++  +  +L ++ D    +  L  +       + E+    + L
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK------REQEVTVLKKAL 1190

Query: 1145 KKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRL 1204
             + TR  E+  Q  +  + + +E        L++++   ++     +   +++  E   L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVE-------ELTEQLEQFKRAKANLDKNKQTLEKENADL 1243

Query: 1205 TSENMMIPDFKQQI----SELEKQKQDLEIR----------LNEQAEKMKGKLEELSNQL 1250
              E  ++   KQ++     +LE Q Q+L+ +          LN++  K++ ++E ++  L
Sbjct: 1244 AGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1303

Query: 1251 HRSQ-------EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDHLKKQFETES 1300
            + ++       ++  +    L+   E+    T++K  +  K+++++E  + L+ Q + E 
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363

Query: 1301 EVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
            E K N  +  S L ++  D +++L      ++ L++  K   K I
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1408



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 107/479 (22%), Positives = 221/479 (46%), Gaps = 60/479 (12%)

Query: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953
            L K  +   KEN  L  +L  L   +     K +KLEA++++  +   +    G+R R  
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD----GERARAE 1284

Query: 954  VEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDD---VQKEERQRML 1010
            + +K+ KLQ   +E+E+    +  + + K  +L + + +L+ QL D    +Q+E RQ++ 
Sbjct: 1285 LNDKVHKLQ---NEVESVTGMLN-EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL- 1339

Query: 1011 LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKT 1070
               +   K +  E++  SL++++    DE+M+ +  +E  H+++  ++     LS   K 
Sbjct: 1340 ---NVSTKLRQLEEERNSLQDQL----DEEMEAKQNLE-RHISTLNIQ-----LSDSKKK 1386

Query: 1071 ISEFEKEIELLQAQKIDVEKHVQSQKREMREKMS-----EITKQLLESYDIEDV-----R 1120
            + +F   +E L+  K   +K +++  ++  EK +     E TK  L+  +++D+      
Sbjct: 1387 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-ELDDLVVDLDN 1445

Query: 1121 SRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEI 1180
             R  V +LE      +   A E      + + S +  ++D  E E      K + L++ +
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEE------KNISSKYADERDRAEAEAREKETKALSLARAL 1499

Query: 1181 NHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMK 1240
                +   E    N+ ++ E+  L S      D  + + ELEK K+ LE     Q E+MK
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSK---DDVGKNVHELEKSKRALET----QMEEMK 1552

Query: 1241 GKLEELSNQLHRSQEEE-----------GTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS 1289
             +LEEL ++L  +++ +           G   + L+A++E + +++ +L  ++ E +   
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612

Query: 1290 DHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKA 1348
            +  +KQ    +  K     +   L L+     +  +   + ++KLQ Q+K   + +  A
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 94/482 (19%), Positives = 208/482 (43%), Gaps = 51/482 (10%)

Query: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGD-VEKIQK-L 929
            +R+F  +     NI   Y  +R + + E + KE   L        AL A + +E+  K L
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1516

Query: 930  EAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKE- 988
            +AE+E   + +           D V + + +L+K    LETQ E+++ +L+E  +EL+  
Sbjct: 1517 KAEMEDLVSSK-----------DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565

Query: 989  ---------KMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDE 1039
                      M  L  Q   D+Q  + Q     +  + +  +YE +++  +++       
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625

Query: 1040 KMQLQHLVEGEHVTSD----GLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
            K +L+  ++   + +D    G +  + +L K    + +F++E+E  +A + ++    +  
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +++ +   +++ +   +    E  R +  +E  E   E          L+   R LE+  
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745

Query: 1156 QSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDI---NESIRHEVTRLTSENM 1209
               ++  E+E   +EA++ +V   +Q+   L      E      NES R ++ R      
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN---- 1801

Query: 1210 MIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269
                 K+  S+L + +  ++ +       ++ K+ +L  Q+ +   E+    K+L+ +++
Sbjct: 1802 -----KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856

Query: 1270 ------IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEE 1323
                  +  +++ K+ ++ +E  E  +   KQ + + E      +E+ R+    R L+ E
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE---EAEEESQRINANRRKLQRE 1913

Query: 1324 LD 1325
            LD
Sbjct: 1914 LD 1915



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 152/726 (20%), Positives = 287/726 (39%), Gaps = 91/726 (12%)

Query: 707  ELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKH 766
            ++  + K+E  +  L RL  +  Q      KI    G ++ L++  LD  R +    +K 
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE-DLDSERAARNKAEKQ 1147

Query: 767  MRGWLQR----KKFLRERRAALIIQQYFRGQQTVRKAITAVALKE------AWAAIIIQK 816
             R   +     K  L +   +   QQ  R ++     +   AL E      A    + QK
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1207

Query: 817  HCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQ 876
            H          Q +   T  ++ + R      + ++ LE+  A +  +      A++  +
Sbjct: 1208 HA---------QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1258

Query: 877  SIRRFVLNIQLTYRVQRLQKKLEDQ-------NKENHGL---VEKLTSLAALRAGDVEKI 926
              ++     +L  +VQ LQ K  D        N + H L   VE +T +     G   K+
Sbjct: 1259 HKKK-----KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313

Query: 927  QKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQ-KEQIQLK--LQEKT 983
             K  A L       +   ++  R +  V  KL +L++  + L+ Q  E+++ K  L+   
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373

Query: 984  EELKEKMDNLTKQLFD---DVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEK 1040
              L  ++ +  K+L D    V+  E  +   +K  E  TQ YE++  +  +    L+  K
Sbjct: 1374 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK----LEKTK 1429

Query: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100
             +LQ  ++   V  D  +  V+ L K+ +   +   E + + ++  D     +++ RE  
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489

Query: 1101 EKMSEITKQLLESYDIEDVRSRLS------VEDLEHLNED-GELWFAYEGLKKATRVLES 1153
             K   + + L E+ + ++   R +      +EDL    +D G+     E  K+A      
Sbjct: 1490 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549

Query: 1154 HFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREE----NDINESIRHEVTRLTSE-N 1208
              ++Q +  E E++A     + L   +  L+  F  +    ++ NE  R ++ R   E  
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1609

Query: 1209 MMIPDFKQQIS-------ELEKQKQDLEIRLN------EQAEKMKGKLEELSNQLHRSQE 1255
              + D ++Q +       +LE   +DLE++ +      E+A K   KL+       R  E
Sbjct: 1610 TELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELE 1669

Query: 1256 EEGTQRKALEA---QNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASR 1312
            +    R  + A   +NE   K  E  + ++QE   A++  +KQ + E E           
Sbjct: 1670 DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE----------- 1718

Query: 1313 LTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGK-ANDVHSSSGPKEYLGMLQYKREDE 1371
                  +L EEL         LQD+ + L   I +   ++    G  E +     K   +
Sbjct: 1719 ------ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 1772

Query: 1372 AKLIQN 1377
            A+ + N
Sbjct: 1773 AEQLSN 1778



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)

Query: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
            +Q  E++ ++ +L+ +  E+ +K + +L+EL  +  +  EE+   ++ L+A+ E++ + +
Sbjct: 856  RQEEEMQAKEDELQ-KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 914

Query: 1276 E---KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIK 1332
            E   +L  K QE++E    ++ + E E +     + E  ++  +  DLEE+L+ ++   +
Sbjct: 915  EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974

Query: 1333 KLQDQVKTLSKTIGKANDVHSSSGPKEYLGM--LQYKREDEAKLIQNLILDL 1382
            KLQ +  T    I K  D        E L M     K   E KL++  I DL
Sbjct: 975  KLQLEKVTAEAKIKKLED--------EILVMDDQNNKLSKERKLLEERISDL 1018


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score =  595 bits (1535), Expect = e-170
 Identities = 439/1439 (30%), Positives = 721/1439 (50%), Gaps = 107/1439 (7%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            V++ DP+E +  A +    R G KV        T    +V  + + P+ NP       D+
Sbjct: 38   VFVVDPKESFVKATVQS--REGGKVTAKTEAGAT---VTVKDDQVFPM-NPPKYDKIEDM 91

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              +++LHEPAVL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   +
Sbjct: 92   AMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189
              PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G       
Sbjct: 151  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210

Query: 190  --------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYL 241
                    +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYL
Sbjct: 211  TSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270

Query: 242  LEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDR 300
            LEKSRV FQ + ER+YHIFYQ+ ++ ++ +   + L +   ++Y  +  G   +  ++D+
Sbjct: 271  LEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQ 329

Query: 301  AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360
             E++ T     +LGF  D ++ ++K+  A++H GN++      E  +  +          
Sbjct: 330  EELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389

Query: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
            L  L S  + + LC  ++   +E V K  T  Q  NA  ALAK +Y  +F ++V RINQ 
Sbjct: 390  LQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQ 449

Query: 421  LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480
            L     +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 450  LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509

Query: 481  PWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
             WT IDF  D    I+LIE  MGI  +L+EEC+ P  TD ++  KLY   + ++  F+KP
Sbjct: 510  EWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKP 569

Query: 540  RMS----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595
            + +       F + H+A  V+Y   G+L+KN+D + + +V + + S     A  F     
Sbjct: 570  KPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF----- 624

Query: 596  PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
                 G+       K+  K     F+ TV + FR +L  LM  L +T PH+VRCI PN+ 
Sbjct: 625  -VGATGAEAEAGGGKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682

Query: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713
            K P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E  F D 
Sbjct: 683  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 742

Query: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
            K+  + +L  +  D  QY+FG TK+FF+AG +  LE++R +KL Q     Q   RG+L R
Sbjct: 743  KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLAR 802

Query: 774  KKFLR--ERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIR 831
             ++ +  ERR ++   QY          + A    + W  + +    +  L++S      
Sbjct: 803  VEYQKMVERRESIFCIQY---------NVRAFMNVKHWPWMKLYFKIKP-LLKSAETEKE 852

Query: 832  MATI------TMQAYSRGFLARRRYRK----MLEEHKAVILQKYARA-WLARRRFQSIRR 880
            MA +      T +  ++    R+   +    +++E   + LQ  A A  LA    +  + 
Sbjct: 853  MANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL 912

Query: 881  FVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHR 940
                IQL  +++ + ++ ED+ + N  L  K   L    +   + I  LE  L K    +
Sbjct: 913  IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972

Query: 941  RNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKMD 991
               E K K   +    ++E +AKL K    L+   +Q    LQ + +++      K K++
Sbjct: 973  HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032

Query: 992  NLTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEKM 1041
                 L   +++E++ RM LE          K  +  T D E   Q L E++K  + E  
Sbjct: 1033 QQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMS 1092

Query: 1042 QLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMRE 1101
             LQ  +E E      L+ ++  L  +   I E E+EIE  +A +   EK    Q+ ++  
Sbjct: 1093 GLQSKIEDEQALGMQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QRSDLSR 1145

Query: 1102 KMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKKATRVL 1151
            ++ EI+++L E     S  IE  + R +       DLE      E   A    K A  V 
Sbjct: 1146 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA 1205

Query: 1152 E-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTS 1206
            E      + Q  K   EKE   +  ++  L+   ++++ + + + ++ +  R    +L+ 
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA---SNMETVSKAKGNLEKMCRALEDQLSE 1262

Query: 1207 ENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEA 1266
                  + ++ I++L  Q+  L+    E + ++  K + L +QL R ++    Q + L+ 
Sbjct: 1263 IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEK-DTLVSQLSRGKQAFTQQIEELKR 1321

Query: 1267 QNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEEL 1324
            Q E   K K  L   +Q  +   D L++Q+E E E K   ++  S+   E      + E 
Sbjct: 1322 QLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYET 1381

Query: 1325 DMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
            D   R  ++L++  K L++ +  A +   +   K     L+  ++     +++L++D++
Sbjct: 1382 DAIQRT-EELEEAKKKLAQRLQDAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMIDVE 1437



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 99/525 (18%), Positives = 222/525 (42%), Gaps = 45/525 (8%)

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
            T +++ L+++LE++ K    L   L S      L     E+ Q+ +AEL++A        
Sbjct: 1313 TQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEV 1372

Query: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
            A  R  YE    +  + +EE   KL +   + E   E +  K     E+ K+++ N  + 
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS-LEKTKQRLQNEVED 1431

Query: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
            L  DV++       L+K           ++ K ++   ++++ ++E ++L  E  ++++ 
Sbjct: 1432 LMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNA 1491

Query: 1047 VEGEHVTSDGLKAEVARLSKQV-----------KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
             E      + LK E   L +++           K I E EK  + ++ +K +++  ++  
Sbjct: 1492 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEA 1551

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
            +  +  +  +I +  LE   ++    R   E  E +++            ++T  L++  
Sbjct: 1552 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQST--LDAEI 1609

Query: 1156 QSQKDCY--EKEIEA-LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIP 1212
            +S+ D    +K++E  LN   + L+       +  R   +    ++     L        
Sbjct: 1610 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE 1669

Query: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNE 1269
            D K+Q++ +E++   L+  +    E+++  LE+       +++E  + ++R + L  QN 
Sbjct: 1670 DLKEQLAMVERRANLLQAEI----EELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1725

Query: 1270 IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329
                 K+KL   I ++Q   + + ++     E       +A+ +  E +  ++     +R
Sbjct: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785

Query: 1330 VIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
            + K L+  VK L   + +A  +    G K+   +    RE E ++
Sbjct: 1786 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 81/407 (19%), Positives = 174/407 (42%), Gaps = 42/407 (10%)

Query: 753  LDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAI 812
            L+K+++     +  ++  L+  +   E     I++      Q   +    +A K+     
Sbjct: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589

Query: 813  IIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLAR 872
            + + H R  +V S+      +T+  +  SR    R + +   + ++  I   +A    A 
Sbjct: 1590 MKRNHIR--IVESM-----QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE 1642

Query: 873  --RRFQSIRRFVLNIQLTYRVQRLQKKLEDQN--KENHGLVEKLTSLAALRAGDVEKIQK 928
              R +++ +  + + QL      L   L  Q   KE   +VE+  +L  L+A    +I++
Sbjct: 1643 ALRNYRNTQAILKDTQL-----HLDDALRSQEDLKEQLAMVERRANL--LQA----EIEE 1691

Query: 929  LEAELEKAATHRRNYEEKGKRYRDAVE---EKLAKLQKHNSELETQKEQIQLKLQEKTEE 985
            L A LE+    R+  E++     + V+    +   L     +LET   QIQ ++++  +E
Sbjct: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQE 1751

Query: 986  LKEKMDNLTKQLFD------DVQKEERQRMLLE---KSFELKTQDYEKQIQSLKEEIKAL 1036
             +   +   K + D      +++KE+     LE   K+ E   +D + ++   ++   AL
Sbjct: 1752 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ--LAL 1809

Query: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHV---Q 1093
            K  K Q+Q L          +++E  R  + VK + + E++++ L  Q  +  K++   Q
Sbjct: 1810 KGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQ 1869

Query: 1094 SQKREMREKMSEITKQLLESYDIEDV---RSRLSVEDLEHLNEDGEL 1137
                +++ K+    +Q  E+ +  +V   + R    +LE   E  ++
Sbjct: 1870 DLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADI 1916


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score =  595 bits (1534), Expect = e-169
 Identities = 443/1444 (30%), Positives = 717/1444 (49%), Gaps = 117/1444 (8%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGT-----ELDYSVNPESLPPLRNPDILV 67
            V++ DP+E +  A +    R G KV        T     +  +S+NP     +       
Sbjct: 38   VFVVDPKESYVKAIVQS--REGGKVTAKTEAGATVTVKEDQVFSMNPPKYDKIE------ 89

Query: 68   GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127
               D+  +++LHEPAVL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G
Sbjct: 90   ---DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRG 145

Query: 128  QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187
            +   +  PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G  
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205

Query: 188  AH-----------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGAN 236
                         +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A+
Sbjct: 206  KKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASAD 265

Query: 237  MSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIE 295
            + TYLLEKSRV FQ + ER+YHIFYQ+ ++ ++ E   + L +   +++  +  G   + 
Sbjct: 266  IETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIEMLLITTNPYDFAFVSQGEITVP 324

Query: 296  GVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHL 355
             ++D+ E++ T     +LGF  D ++ ++K+  A++H GN++      E  +  +     
Sbjct: 325  SIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA 384

Query: 356  KVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVE 415
                 L  L S  + + LC  ++   +E V K  T  Q  NA  ALAK IY  +F ++V 
Sbjct: 385  DKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVT 444

Query: 416  RINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEY 475
            RINQ L     +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY
Sbjct: 445  RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504

Query: 476  MKEDIPWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNP 534
             KE I W  IDF  D    I+LIE  MGI  +L+EEC+ P  TD ++  KLY   + ++ 
Sbjct: 505  KKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSN 564

Query: 535  LFEKPRMS----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFF 590
             F+KP+ +       F + H+A  V+Y   G+L+KN+D + + +V + + S     A  F
Sbjct: 565  NFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLF 624

Query: 591  QENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCI 650
                T  +  G        K+  K     F+ TV + FR +L  LM  L +T PH+VRCI
Sbjct: 625  SGAQTAEAEGG------GGKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCI 677

Query: 651  KPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QEL 708
             PN+ K P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E 
Sbjct: 678  IPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEG 737

Query: 709  SFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMR 768
             F D K+  + +L  +  D  QY+FG TK+FF+AG +  LE++R +KL Q     Q   R
Sbjct: 738  QFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICR 797

Query: 769  GWLQRKKF--LRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSL 826
            G+L R +F  + ERR ++   QY          I A    + W  + +    +  L++S 
Sbjct: 798  GFLMRVEFRKMMERRESIFCIQY---------NIRAFMNVKHWPWMKLYFKIKP-LLKSA 847

Query: 827  YQLIRMATI------TMQAYSRGFLARRRYRK----MLEEHKAVILQKYARA-WLARRRF 875
                 MA +      T +  ++    R+   +    +++E   + LQ  A A  LA    
Sbjct: 848  ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEE 907

Query: 876  QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEK 935
            +  +     IQL  +++ + ++ ED+ + N  L  K   L    +   + I  LE  L K
Sbjct: 908  RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967

Query: 936  AATHRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------ 986
                +   E K K   +    ++E +AKL K    L+   +Q    LQ + +++      
Sbjct: 968  VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKA 1027

Query: 987  KEKMDNLTKQLFDDVQKE-------ERQRMLLEKSFEL---KTQDYEKQIQSLKEEIKAL 1036
            K K++     L   +++E       ER +  LE   +L    T D E   Q L E++K  
Sbjct: 1028 KTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKK 1087

Query: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQK 1096
            + E   LQ  +E E   +  L+ ++  L  +   I E E+EIE  +A +   EK    Q+
Sbjct: 1088 EFEMSNLQGKIEDEQALAIQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QR 1140

Query: 1097 REMREKMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKK 1146
             ++  ++ EI+++L E     S  IE  + R +       DLE      E   A    K 
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200

Query: 1147 ATRVLE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEV 1201
            A  V E        Q  K   EKE   L  ++  L+  +  + K       +  ++  ++
Sbjct: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260

Query: 1202 TRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQR 1261
            + + ++     + ++ I+EL  QK  L     E + ++  K + + +QL R ++    Q 
Sbjct: 1261 SEIKTKE---EEQQRLINELSAQKARLHTESGEFSRQLDEK-DAMVSQLSRGKQAFTQQI 1316

Query: 1262 KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD-- 1319
            + L+ Q E  TK K  L   +Q  +   D L++Q+E E E K   ++  S+   E     
Sbjct: 1317 EELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWR 1376

Query: 1320 LEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLI 1379
             + E D   R  ++L++  K L++ +  A +   +   K     L+  ++     +++L+
Sbjct: 1377 TKYETDAIQRT-EELEEAKKKLAQRLQDAEEHVEAVNSK--CASLEKTKQRLQNEVEDLM 1433

Query: 1380 LDLK 1383
            +D++
Sbjct: 1434 IDVE 1437



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 107/533 (20%), Positives = 234/533 (43%), Gaps = 61/533 (11%)

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
            T +++ L+++LE++ K    L   L S      L     E+ Q+ +AEL++         
Sbjct: 1313 TQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEV 1372

Query: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
            A  R  YE    +  + +EE   KL +   + E   E +  K     E+ K+++ N  + 
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCAS-LEKTKQRLQNEVED 1431

Query: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
            L  DV++     + L+K           ++ K ++ + ++++ ++E ++L  E  ++++ 
Sbjct: 1432 LMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNA 1491

Query: 1047 VEG--EHVTS-----DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
             E   +H+ +       L+ E++ L++Q+    K I E EK  + L  +K +++  ++  
Sbjct: 1492 YEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEA 1551

Query: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKA-TRVLESH 1154
            +  +  +  +I +  LE   ++    R   E  E L++          LK+   RV+ES 
Sbjct: 1552 EASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQ----------LKRNHLRVVES- 1600

Query: 1155 FQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDF 1214
             QS  D    EI + N  +    +    L ++  + N  N      +  L +   ++ D 
Sbjct: 1601 MQSTLDA---EIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDT 1657

Query: 1215 KQQISELEKQKQDLEIRL---NEQAEKMKGKLEELSNQLHRSQE-EEGTQRKALEAQNEI 1270
            +  + +  + + DL+ +L     +A  M+ ++EEL   L R++   +  +++ L+A   +
Sbjct: 1658 QLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERV 1717

Query: 1271 ---HTKE------KEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLE 1321
               HT+       K+KL   I ++Q   + + ++     E       +A+ +  E +  +
Sbjct: 1718 QLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQ 1777

Query: 1322 EELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
            +     +R+ K ++  VK L   + +A  +    G K+   +    RE E+++
Sbjct: 1778 DTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEV 1830



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 104/514 (20%), Positives = 228/514 (44%), Gaps = 63/514 (12%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
            +R + K+L E K    +  A    +++  +S+   +  ++  Y  +     LE   +EN 
Sbjct: 1450 QRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAY--EESLDHLETLKRENK 1507

Query: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA-VEEKLAKLQKHN 965
             L ++++ L    A   + I +LE +++K   H ++  +      +A +E +  K+ +  
Sbjct: 1508 NLQQEISDLTEQIAEGGKHIHELE-KVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQ 1566

Query: 966  SELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKT 1019
             EL   K +I  K+ EK EEL +   N   + + +   +  E R R   + ++K  E   
Sbjct: 1567 LELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDL 1626

Query: 1020 QDYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQV 1068
             + E Q+           ++L+     LKD ++ L   + G+    D LK ++A + ++ 
Sbjct: 1627 NEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQ----DDLKEQLAMVERRA 1682

Query: 1069 KTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-D 1127
              +   + E+E L+A     E+  +  ++E+ +    +  QLL + +   + ++  +E D
Sbjct: 1683 NLM---QAEVEELRASLERTERGRKMAEQELLDASERV--QLLHTQNTSLINTKKKLETD 1737

Query: 1128 LEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQ 1184
            +  +  +                +E   Q  ++  EK  +A+    +    L +E +   
Sbjct: 1738 ISQIQGE----------------MEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781

Query: 1185 KLFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKL 1243
             L R + ++ ++++    RL  +E + +   K+QI +LE + ++LE   +E   + K  +
Sbjct: 1782 HLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELE---SEVESEQKHNV 1838

Query: 1244 EELSN-QLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEV 1302
            E +   + H  + +E T +   + +N +  ++   L+DK+Q   +A     ++ E +S V
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQD---LVDKLQTKVKAYKRQAEEAEEQSNV 1895

Query: 1303 K-CNFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335
                FR    +L  E  + +E  D+ +  + KL+
Sbjct: 1896 NLAKFR----KLQHELEEAKERADIAESQVNKLR 1925


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score =  590 bits (1520), Expect = e-168
 Identities = 435/1424 (30%), Positives = 701/1424 (49%), Gaps = 132/1424 (9%)

Query: 12   RVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGEND 71
            + WIPD E  +  AE+      G  ++     DG  L  S+  + +  +  P+  + E D
Sbjct: 53   KCWIPDGENAYIEAEVKGSEDDGTVIVETA--DGESL--SIKEDKIQQMNPPEFEMIE-D 107

Query: 72   LTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMG 131
            +  L++L+E +VLH L+ R+ +  +IYTYSG+  V +NPYK LP+Y   ++ AY G+   
Sbjct: 108  MAMLTHLNEASVLHTLKRRYGQW-MIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRS 166

Query: 132  DMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVS-------KS 184
            +  PHIFAVA  A++ M  N  NQSI+ +GESGAGKTV++++ ++YFAT++       K 
Sbjct: 167  EAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ 226

Query: 185  GSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244
            G+   +ED+++ +N I EA GNAKT RNDNSSRFGK+  + F  +  +   ++  YLLEK
Sbjct: 227  GA---LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEK 283

Query: 245  SRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAE--EFNYTRMGGNTVIEGVNDRAE 302
            SRV+FQ   ERNYHIFYQ+ +   Q E   L L SA   +F++   G  TV E ++D  E
Sbjct: 284  SRVIFQQAGERNYHIFYQILSG--QKELHDLLLVSANPSDFHFCSCGAVTV-ESLDDAEE 340

Query: 303  MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362
            ++ T++   +LGF  D +   +K+  AI+H GN++      E    ++   +      L+
Sbjct: 341  LLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLM 400

Query: 363  GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422
            G+ S  + + L + +I   +E V +  T  Q   A  AL+K +Y  +F ++V RIN+AL 
Sbjct: 401  GINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALD 460

Query: 423  FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                +  FIG+LDI GFE  + NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 461  AKLSRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEW 520

Query: 483  TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541
              I F  D Q  IDLIE  MGIL +L+EEC+ P  TD  +  KL++N   ++   +KP+ 
Sbjct: 521  VSIGFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP 580

Query: 542  S----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597
                    F + H+A  V Y   G+LEKN+D + + +V + + S   L A+ F+   +  
Sbjct: 581  DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTD 640

Query: 598  S--PFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
            S  PFG     K A             TV S  + +L  LM  L +T PH+VRCI PN  
Sbjct: 641  SAIPFGEKKRKKGAS----------FQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVN 690

Query: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MTKQELSFSDK 713
            K+P   D   ++QQLR  GVLE  RI  + +P+R  Y +F  RY IL   T  +  F   
Sbjct: 691  KIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSS 750

Query: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
            ++  + +L  L  D  QY+FG TK+FF+AG +  LE +R ++L +   + Q   +G L R
Sbjct: 751  RKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMR 810

Query: 774  KKF---LRERRAALIIQQYFRGQQTVRK---AITAVALKEAWAAIIIQKHCRGYLVRSLY 827
             KF   L ER A ++IQ   R    V+          +K    +  + +   G L     
Sbjct: 811  IKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAG-LKEECA 869

Query: 828  QLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQL 887
            QL     +    + R  L  ++     E++  ++  +  +  LA    Q        IQL
Sbjct: 870  QL--QKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQL 927

Query: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKG 947
              RV+ L +++E++ + N  L  +   L        ++I  LE  L K+   +R  E K 
Sbjct: 928  EARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKV 987

Query: 948  KRYRDAV-------------------------------EEKLAKLQKHNSELETQKEQIQ 976
            K   + V                               EEKL+ L K N +LE Q ++++
Sbjct: 988  KNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELE 1047

Query: 977  LKLQEKTE-------ELKEKMDN--LTKQLFDDVQKEERQ--RMLLEKSFEL-----KTQ 1020
              L+++ +       EL +   N  L ++  ++++  +R     L +K  EL     K +
Sbjct: 1048 GALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVE 1107

Query: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
            + +  +  L++ +K L+ +   L+  +E E  T   ++ E A L++ +  ++E  +E+  
Sbjct: 1108 NEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGG 1167

Query: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
                ++++ K  +++ +++   M E T         E   + L     + L E       
Sbjct: 1168 SSLAQLEITKKQETKFQKLHRDMEEAT------LHFETTSASLKKRHADSLAE------- 1214

Query: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
             EG  +  + ++   +  K   + E++ L  +V  +++   + +KL      + E   HE
Sbjct: 1215 LEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLC----TLYEERLHE 1270

Query: 1201 VT-RLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGT 1259
             T +L     +  D   Q ++L  +  +   RL E+        E L NQL R +     
Sbjct: 1271 ATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK--------EALINQLSREKSNFTR 1322

Query: 1260 QRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEAS-------- 1311
            Q + L  Q E  TK +  L   +Q+ Q   D L++Q+E E EVK    +  S        
Sbjct: 1323 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQ 1382

Query: 1312 -RLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSS 1354
             R+  EN  ++   D++D   K+L  +++  ++ +G AN  ++S
Sbjct: 1383 WRMKYENNVIQRTEDLED-AKKELAIRLQEAAEAMGVANARNAS 1425



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 124/571 (21%), Positives = 245/571 (42%), Gaps = 77/571 (13%)

Query: 850  YRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909
            + + LEE +A+I Q         R+ + +R             +L+K+ + Q+   H L 
Sbjct: 1299 FLRRLEEKEALINQLSREKSNFTRQIEDLRG------------QLEKETKSQSALAHALQ 1346

Query: 910  EKLTSLAALRAGDVEKIQKLEAELEKAATH--------RRNYE----EKGKRYRDAVEEK 957
            +       LR    E+ Q+++AEL +  +         R  YE    ++ +   DA +E 
Sbjct: 1347 KAQRDCDLLRE-QYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKEL 1405

Query: 958  LAKLQK----------HNSELETQKEQIQLKLQEKTEEL----------KEKMDNLTKQL 997
              +LQ+           N+ LE  + Q+QL+L +   +L           +K     K L
Sbjct: 1406 AIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKAL 1465

Query: 998  FDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALK---DEKMQLQHLVEGEHVTS 1054
             D  QK E  + LL+ S        +K++Q+L  E+  LK   +E +  Q  +  E+   
Sbjct: 1466 ADWKQKHEESQALLDAS--------QKEVQALSTELLKLKNTYEESIVGQETLRREN--- 1514

Query: 1055 DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL 1110
              L+ E++ L+ QV    K ++E EK  +L++ +K +V+  ++  +  +    S+I    
Sbjct: 1515 KNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQ 1574

Query: 1111 LESYDIE-DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCY---EKEI 1166
            LE  + + ++  +LS +D E  N   +     + L+ +   L+S  +S+ +     +K  
Sbjct: 1575 LELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSS---LDSEAKSRIEVTRLKKKME 1631

Query: 1167 EALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQ 1226
            E LN   + LS     + +  +    +   I+    +L     +  D K+Q++  E++  
Sbjct: 1632 EDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNS 1691

Query: 1227 DLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQRKAL-EAQNEIHTKEKEKLIDKIQ 1283
             L+  L    E ++   E+       S+EE  E T+R  L   QN     +K+KL   + 
Sbjct: 1692 LLQSEL----EDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVA 1747

Query: 1284 EMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343
             MQ+ ++ + ++ +   E       EA+ L+ E +  ++ +   +R  + ++  +  L K
Sbjct: 1748 RMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQK 1807

Query: 1344 TIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
             + +A  +      K+   +    RE E +L
Sbjct: 1808 RLAEAEQMALMGSRKQIQKLESRVRELEGEL 1838



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 95/426 (22%), Positives = 185/426 (43%), Gaps = 56/426 (13%)

Query: 1031 EEIKALKDEKMQLQHLVEGEHVTSDGLKAE-----------VARLSKQVKTISEFEKEIE 1079
            EE+  LK+E  QLQ  +E      + LKA+           + +L  + +T++  E++ E
Sbjct: 859  EEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCE 918

Query: 1080 LLQAQKIDVE---KHVQSQKREMREKMSEIT-------------KQLLESYDIEDVRSRL 1123
             L   KI +E   K +  +  E  E  SE+T             K+ ++  +   V+S  
Sbjct: 919  WLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEK 978

Query: 1124 SVEDLEH--LNEDGELWFAYEGLKKATR----VLESHFQSQKDCY--EKEIEALNFKVVH 1175
                 EH   N   E+ F  E + K  R    V E+H Q+  D +  E+++ +L+   + 
Sbjct: 979  EKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLK 1038

Query: 1176 LSQEINHLQKLFREENDINESIRHEV------TRLTSENMMIPDFKQQISELEKQKQDLE 1229
            L Q+++ L+    +E     +   E+       +L  E+M   +  Q+    E +K++LE
Sbjct: 1039 LEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELE 1098

Query: 1230 I-RLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEA 1288
            + ++N + E  KG + +L   +   Q +    ++ LEA+     K + +  D  Q++ + 
Sbjct: 1099 LSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL 1158

Query: 1289 SDHLKKQFETE-SEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGK 1347
            ++ L++   +  ++++   +QE     L +RD+EE           L  +  + S     
Sbjct: 1159 NERLEEVGGSSLAQLEITKKQETKFQKL-HRDMEE---------ATLHFETTSASLKKRH 1208

Query: 1348 ANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYA 1407
            A+ +    G  E L  ++ K E +   +Q  + DL  R   V  +    A+   +C  Y 
Sbjct: 1209 ADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR---VEQMTRAKANAEKLCTLYE 1265

Query: 1408 DSLNDA 1413
            + L++A
Sbjct: 1266 ERLHEA 1271



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 118/523 (22%), Positives = 231/523 (44%), Gaps = 79/523 (15%)

Query: 874  RFQSIRRFVLNIQLTYRVQR--LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQ---- 927
            +FQ + R +    L +      L+K+  D   E  G VE L  +      D   +Q    
Sbjct: 1182 KFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVD 1241

Query: 928  KLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHN---SELETQKEQIQLKLQEKTE 984
             L   +E+    + N E+    Y + + E  AKL K     ++L  QK ++  +  E   
Sbjct: 1242 DLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLR 1301

Query: 985  ELKEK---MDNLTKQLFDDVQKEERQRMLLEKSFELKTQD-YEKQIQSLKEEIKALKDEK 1040
             L+EK   ++ L+++  +  ++ E  R  LEK  E K+Q      +Q  + +   L+++ 
Sbjct: 1302 RLEEKEALINQLSREKSNFTRQIEDLRGQLEK--ETKSQSALAHALQKAQRDCDLLREQY 1359

Query: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100
             + Q +    H T   + AE+      V+   ++E  +        D +K +  + +E  
Sbjct: 1360 EEEQEVKAELHRTLSKVNAEM------VQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413

Query: 1101 EKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGL--------KKATRVLE 1152
            E M     +   +  +E  R +L +E  + L++ G++  A   L        K      +
Sbjct: 1414 EAMGVANAR---NASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470

Query: 1153 SHFQSQK--DCYEKEIEALNFKVVHLSQEINHL---QKLFREENDINESIRHEVTRLTSE 1207
             H +SQ   D  +KE++AL+ +++ L          Q+  R EN   ++++ E++ LT++
Sbjct: 1471 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRREN---KNLQEEISNLTNQ 1527

Query: 1208 NMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEE-GTQRKALEA 1266
               + +  + ++E+EK K+ +E    E+  +++  LEE    L R++ +    Q + LEA
Sbjct: 1528 ---VREGTKNLTEMEKVKKLIE----EEKTEVQVTLEETEGALERNESKILHFQLELLEA 1580

Query: 1267 QNEIHTK--EKEKLIDKIQEMQEAS------------------DHLKKQFET-----ESE 1301
            + E+  K  EK++ I+  +  Q+ +                    LKK+ E      E +
Sbjct: 1581 KAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ 1640

Query: 1302 VKCNFRQ--EASR----LTLENRDLEEELDMKDRVIKKLQDQV 1338
            + C  RQ  EA++    L ++ +DL+ +LD   ++   L++QV
Sbjct: 1641 LSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQV 1683



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 43/203 (21%), Positives = 92/203 (45%), Gaps = 18/203 (8%)

Query: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK---- 946
            V R+QK+ E+  +E     EK    A   A   E+++K +  +      R N E+     
Sbjct: 1746 VARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDL 1805

Query: 947  GKRYRDAVEEKLAKLQKHNSELETQKEQIQLKL----------QEKTEELKEKMDNLTKQ 996
             KR  +A +  L   +K   +LE++  +++ +L          Q     L+  +  LT Q
Sbjct: 1806 QKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQ 1865

Query: 997  LFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDG 1056
              +D +   R +  ++K  +LK Q+Y++Q++  + +      +  + QH +      ++ 
Sbjct: 1866 AEEDKKNLSRMQTQMDK-LQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEV 1924

Query: 1057 LKAEVARLSKQVKTISEFEKEIE 1079
             +++V +L  + +   EF K+++
Sbjct: 1925 AESQVNKLKIKAR---EFGKKVQ 1944


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  588 bits (1517), Expect = e-167
 Identities = 436/1427 (30%), Positives = 721/1427 (50%), Gaps = 155/1427 (10%)

Query: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
            VW+P  +  ++ A + ++  VG++ +  L+E+G ++   VN + +  + NP       D+
Sbjct: 32   VWVPSDKSGFEPASLKEE--VGEEAIVELVENGKKV--KVNKDDIQKM-NPPKFSKVEDM 86

Query: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
              L+ L+E +VLHNL+ R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 87   AELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHE 145

Query: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----A 188
            M PHI+A+ + AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S  +     
Sbjct: 146  MPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQG 205

Query: 189  HVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVV 248
             +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ TYLLEKSR +
Sbjct: 206  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAI 265

Query: 249  FQSENERNYHIFYQLCASAQQSEFKHLKLG-SAEEFNYTRM--GGNTVIEGVNDRAEMVE 305
             Q++ ER +HIFY L + A +    HLK     E +N  R    G+  I G  D+    E
Sbjct: 266  RQAKEERTFHIFYYLLSGAGE----HLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQE 321

Query: 306  TQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLGLE 365
            T +   ++G  E+ QM + ++++ +L LGN+      N   +   D++  +    LLG+ 
Sbjct: 322  TMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGIN 381

Query: 366  SGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQFSG 425
                 + +   +I    + V K  T+ QA  A +ALAK  Y  +F ++V RIN+AL  + 
Sbjct: 382  VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441

Query: 426  KQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTL 484
            +Q  +FIG+LDI GFE FD+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W  
Sbjct: 442  RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501

Query: 485  IDF-YDNQPVIDLIE---AKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR 540
            IDF  D QP IDLIE      GIL LLDEEC  P  TD+++++K+       +P F+KP+
Sbjct: 502  IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQE-QGTHPKFQKPK 560

Query: 541  M--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPS 598
                   F I H+A KV+YK + +L KN D + D +  +L  S     +  +++      
Sbjct: 561  QLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKD----VD 616

Query: 599  PFGSMITVKSAKQVIKPNS----KHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPND 654
                +  V    +   P +    K    TVG  ++  L  LM TL  T P++VRCI PN 
Sbjct: 617  RIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNH 676

Query: 655  EKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDK 713
            EK   + D   ++ QLR  GVLE IRI  Q +P+R  + EF  RY IL        F D 
Sbjct: 677  EKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDG 736

Query: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
            K+ C +++  L  DSN Y+ G++K+FFRAG +A+LE+ R  K+    +  Q   RG+L R
Sbjct: 737  KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796

Query: 774  KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYL----------- 822
            K F + ++           Q T  K              ++Q++C  YL           
Sbjct: 797  KAFAKRQQ-----------QLTAMK--------------VLQRNCAAYLKLRNWQWWRLF 831

Query: 823  --VRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARR-----RF 875
              V+ L Q+ R     M       L + R +++  E++   ++      +A +     + 
Sbjct: 832  TKVKPLLQVSRQEEEMMAKEEE--LVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL 889

Query: 876  QSIRRFV-----LNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLE 930
            Q+          L  +LT + Q L++   D         E+   L A +    + IQ+LE
Sbjct: 890  QAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949

Query: 931  AELEKAATHRRNY-------EEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQ 980
             +LE+  + R+         E K K+  +    +E++  KL K    LE +  +    L 
Sbjct: 950  EQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009

Query: 981  EKTE------ELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKE 1031
            E+ E      +LK K + +   L + +++EE+QR  LEK+    E  + D   QI  L+ 
Sbjct: 1010 EEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069

Query: 1032 EIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK- 1090
            +I  L   KMQL    E        ++ E A+ +  +K I E E +I  LQ + ++ E+ 
Sbjct: 1070 QIAEL---KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQ-EDLESERA 1125

Query: 1091 ---HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKA 1147
                 + QKR++ E++  +  +L ++ D     S  + ++L    E  E+    + L++ 
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLD-----STAAQQELRSKREQ-EVNILKKTLEEE 1179

Query: 1148 TRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSE 1207
             +  E+  Q  +  + + +E        L++++   +++        +++ +E   L +E
Sbjct: 1180 AKTHEAQIQEMRQKHSQAVE-------ELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232

Query: 1208 NMMI----PDFKQQISELEKQKQDLEIRLNE----------QAEKMKGKLEELSNQLHRS 1253
              ++     D + +  ++E Q Q+L+++ NE          +  K++ +L+ ++  L +S
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292

Query: 1254 QEEEGTQRK---ALEAQ-------NEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVK 1303
              +     K   ALE+Q        +   ++K  L  K++++++  +  ++Q E E E K
Sbjct: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAK 1352

Query: 1304 CNFRQEASRLTLENRDLEEE-------LDMKDRVIKKLQDQVKTLSK 1343
             N  ++ + L  +  D++++       L+  + V +KLQ  ++ LS+
Sbjct: 1353 HNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399



 Score = 94.4 bits (233), Expect = 9e-19
 Identities = 150/654 (22%), Positives = 279/654 (42%), Gaps = 95/654 (14%)

Query: 835  ITMQAYSRGFLARRRYRKMLEEHKAV-ILQKYARAWLARRRFQSIRRF-----VLNI--- 885
            I  QA  RG+LAR+ + K  ++  A+ +LQ+   A+L  R +Q  R F     +L +   
Sbjct: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843

Query: 886  --QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNY 943
              ++  + + L K  E Q    + L E  T  + L A  ++  ++L+AE E  A      
Sbjct: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCA------ 897

Query: 944  EEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQK 1003
              + +  R  +  K  +L++   +LE + E+ + + Q    E K+KM    ++L + +++
Sbjct: 898  --EAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAE-KKKMQQNIQELEEQLEE 954

Query: 1004 EERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVAR 1063
            EE  R  L+    L+    E +++ L+EE   L+D+  +L    + + +  D +      
Sbjct: 955  EESARQKLQ----LEKVTTEAKLKKLEEEQIILEDQNCKL---AKEKKLLEDRIAEFTTN 1007

Query: 1064 LSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRL 1123
            L+++ +      K     +A   D+E+ ++ ++++ +E              +E  R +L
Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQE--------------LEKTRRKL 1053

Query: 1124 SVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHL 1183
              +  +  ++  EL           ++ E   Q  K   E+E++A   +V   + + N  
Sbjct: 1054 EGDSTDLSDQIAEL---------QAQIAELKMQLAKK--EEELQAALARVEEEAAQKNMA 1102

Query: 1184 QKLFRE-ENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQA--EKMK 1240
             K  RE E+ I+E      +   S N      +    ELE  K +LE  L+  A  ++++
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162

Query: 1241 GKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETES 1300
             K E+  N L ++ EEE    K  EAQ +          +  Q+  +A + L +Q E   
Sbjct: 1163 SKREQEVNILKKTLEEEA---KTHEAQIQ----------EMRQKHSQAVEELAEQLEQTK 1209

Query: 1301 EVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEY 1360
             VK N   E ++ TLEN   E            L ++VK L +  GK +  H     +  
Sbjct: 1210 RVKANL--EKAKQTLENERGE------------LANEVKVLLQ--GKGDSEHKRKKVEAQ 1253

Query: 1361 LGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLK--S 1418
            L  LQ K  +  ++   L   +    V ++ + GL        +  +DS   + + K  S
Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGL--------LSQSDS-KSSKLTKDFS 1304

Query: 1419 LMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGEEEFMKHNSPQQ 1472
             + S +   +++++E       LS  L       N  ++   EEE  KHN  +Q
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 109/501 (21%), Positives = 201/501 (40%), Gaps = 41/501 (8%)

Query: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEA 931
            +++F  +      I   Y  +R + + E + KE   L     SLA      +E+  + +A
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-----SLARA----LEEAMEQKA 1493

Query: 932  ELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMD 991
            ELE+     R   E     +D V + + +L+K    LE Q E+++ +L+E  +EL+   D
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATED 1553

Query: 992  -NLTKQLFDDVQKEERQRML--LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVE 1048
              L  ++     K + +R L   ++  E K +   +Q++ ++ E   L+DE+ Q    V 
Sbjct: 1554 AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE---LEDERKQRSMAVA 1610

Query: 1049 GEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEI-- 1106
                    LK   A +    K   E  K++  LQAQ  D  + +   +    E +++   
Sbjct: 1611 ARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670

Query: 1107 TKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEI 1166
             ++ L+S + E ++ +  +   E      +     E  + A  +  S  +      EK  
Sbjct: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQ----QERDELADEIANSSGKGALALEEK-- 1724

Query: 1167 EALNFKVVHLSQEINHLQKLFREEND----INESIRHEVTRLTSENMMIPDFKQQISELE 1222
              L  ++  L +E+   Q      ND     N  I    T L  E       +    +LE
Sbjct: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLE 1784

Query: 1223 KQKQDLEIRLNEQAEKMKGK-------LEELSNQLHRSQEEEGTQRKALEAQ-NEIHTKE 1274
            +Q ++L+++L E    +K K       LE    QL    + E  +R+A   Q      K 
Sbjct: 1785 RQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844

Query: 1275 KEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQ------EASRLTLENRDLEEELDMKD 1328
            K+ L+    E + A  +  +  +  + +K   RQ      EA R     R L+ EL+   
Sbjct: 1845 KDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDAT 1904

Query: 1329 RVIKKLQDQVKTLSKTIGKAN 1349
                 +  +V +L   + + +
Sbjct: 1905 ETADAMNREVSSLKNKLRRGD 1925


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  587 bits (1514), Expect = e-167
 Identities = 444/1432 (31%), Positives = 713/1432 (49%), Gaps = 157/1432 (10%)

Query: 7    YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDIL 66
            +T    VWIP     +++A I ++   GD+V+  L E+G +    VN + +  + NP   
Sbjct: 30   WTAKKLVWIPSERHGFEAASIKEER--GDEVMVELAENGKKA--MVNKDDIQKM-NPPKF 84

Query: 67   VGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYS 126
                D+  L+ L+E +VLHNL+ R+  S LIYTYSG+  V +NPYK LPIY + II  Y 
Sbjct: 85   SKVEDMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYR 143

Query: 127  GQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKS-- 184
            G+   +M PHI+A++E AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S  
Sbjct: 144  GKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK 203

Query: 185  GSNAH-----VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMST 239
            G   H     +E ++L +NPI E+ GNAKT +NDNSSRFGK+  I+FD    I+GAN+ T
Sbjct: 204  GRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIET 263

Query: 240  YLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLG-SAEEFNYTRM--GGNTVIEG 296
            YLLEKSR V Q+++ER +HIFYQL + A +    HLK     E FN  R    G   I G
Sbjct: 264  YLLEKSRAVRQAKDERTFHIFYQLLSGAGE----HLKSDLLLEGFNNYRFLSNGYIPIPG 319

Query: 297  VNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLK 356
              D+    ET +   ++GF  +  + + K+++++L  GN+      N   +   +++  +
Sbjct: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379

Query: 357  VFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVER 416
              C LLG+      + +   +I    + V K  T+ QA  A +ALAK  Y  LF ++V R
Sbjct: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439

Query: 417  INQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEY 475
            IN+AL  + +Q  +FIG+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQEEY
Sbjct: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499

Query: 476  MKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKLYNNFVN 531
             +E I W  IDF  D QP IDLIE      G+L LLDEEC  P  TD+ +++KL      
Sbjct: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQE-QG 558

Query: 532  RNPLFEKPRM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANF 589
             +  F+KPR       F I H+A KV+YK + +L KN D + D +  +L  S     A  
Sbjct: 559  SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618

Query: 590  F----------QENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETL 639
            +          Q      + FGS    K          K    TVG  ++ SL  LM TL
Sbjct: 619  WKDVDRIVGLDQVTGMTETAFGSAYKTK----------KGMFRTVGQLYKESLTKLMATL 668

Query: 640  NATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRY 699
              T P++VRCI PN EK   + D   ++ QLR  GVLE IRI  Q +P+R  + EF  RY
Sbjct: 669  RNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 728

Query: 700  GILMTKQ-ELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQ 758
             IL        F D K+ C+ ++  L  D N Y+ G++KIFFRAG +A+LE+ R  K+  
Sbjct: 729  EILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITD 788

Query: 759  SCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHC 818
              +  Q   RG+L RK F +++                         ++  A  ++Q++C
Sbjct: 789  IIIFFQAVCRGYLARKAFAKKQ-------------------------QQLSALKVLQRNC 823

Query: 819  RGYL-------------VRSLYQLIRMATITMQAYSRGFL---------------ARRRY 850
              YL             V+ L Q+ R     +QA     L                 R++
Sbjct: 824  AAYLKLRHWQWWRVFTKVKPLLQVTRQEE-ELQAKDEELLKVKEKQTKVEGELEEMERKH 882

Query: 851  RKMLEEHKAVILQKYARAWL-ARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909
            +++LEE   +  Q  A   L A       R      +L   +  L+ ++E++ + N  L 
Sbjct: 883  QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942

Query: 910  EKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELE 969
             +   + A      E++ + E   +K    +   E K K+    +EE++  L+  NS+  
Sbjct: 943  NEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKK----MEEEILLLEDQNSKFI 998

Query: 970  TQKEQIQLKLQEKTEEL---KEKMDNLTK----------QLFDDVQKEERQRMLLEKS-- 1014
             +K+ ++ ++ E + +L   +EK  NL K           L + ++KEE+ R  LEK+  
Sbjct: 999  KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058

Query: 1015 -FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISE 1073
              + +T D + QI  L+ +I  LK +  + +  ++G     D    E    +  +K + E
Sbjct: 1059 KLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDD---ETLHKNNALKVVRE 1115

Query: 1074 FEKEIELLQAQKIDVEK----HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLE 1129
             + +I  LQ +  + EK      + QKR++ E++  +  +L ++ D    +  L  +  +
Sbjct: 1116 LQAQIAELQ-EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174

Query: 1130 HLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFRE 1189
             + E        + L++ T+  E+  Q  +  +   +E L+ ++    +   +L+K  + 
Sbjct: 1175 EVAE------LKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQG 1228

Query: 1190 ENDINESIRHEV-----TRLTSENMMIPDFKQQISELEKQKQD---LEIRLNEQAEKMKG 1241
                N+ +  EV      +  SE+        Q+ EL  +  +   L + L E+A K++ 
Sbjct: 1229 LETDNKELACEVKVLQQVKAESEHKR-KKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287

Query: 1242 KLEELSNQLHRSQ-------EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDH 1291
            +L+ +S  L  ++       ++  +    L+   E+    T++K  L  +I++++E  + 
Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNS 1347

Query: 1292 LKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343
            L++Q E E E + N  ++   L  +  D ++++D     I+ L++  K L K
Sbjct: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1399



 Score =  103 bits (258), Expect = 1e-21
 Identities = 136/594 (22%), Positives = 270/594 (45%), Gaps = 121/594 (20%)

Query: 835  ITMQAYSRGFLARRRYRKMLEEHKAV-ILQKYARAWLARRRFQSIRRFVLNIQLTYRVQR 893
            I  QA  RG+LAR+ + K  ++  A+ +LQ+   A+L  R +Q  R F   ++   +V R
Sbjct: 791  IFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFT-KVKPLLQVTR 849

Query: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953
             +++L+ +++E   + EK T              K+E ELE          E  ++++  
Sbjct: 850  QEEELQAKDEELLKVKEKQT--------------KVEGELE----------EMERKHQQL 885

Query: 954  VEEK--LAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLL 1011
            +EEK  LA+  +  +EL  + E+++ +L  K +EL+E + +L  +    V++EE +  +L
Sbjct: 886  LEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESR----VEEEEERNQIL 941

Query: 1012 EKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTI 1071
            +     + +  +  IQ L+E++    DE+   +  ++ E VT++               I
Sbjct: 942  QN----EKKKMQAHIQDLEEQL----DEEEGARQKLQLEKVTAEA-------------KI 980

Query: 1072 SEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYD----IEDVRSR--LSV 1125
             + E+EI LL+ Q     K    +K+ M ++++E + QL E  +    +  +R++  + +
Sbjct: 981  KKMEEEILLLEDQNSKFIK----EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMI 1036

Query: 1126 EDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQ- 1184
             DLE            E LKK  +  +   +  K   + E   L  ++  L  +I+ L+ 
Sbjct: 1037 SDLE------------ERLKKEEKTRQE-LEKAKRKLDGETTDLQDQIAELQAQIDELKL 1083

Query: 1185 KLFREENDINESIRH---EVTRLTSENMMIPDFKQQISEL--------------EKQKQD 1227
            +L ++E ++  ++     E     +   ++ + + QI+EL              EKQK+D
Sbjct: 1084 QLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD 1143

Query: 1228 LEIRLNEQAEKMKGKLEE------LSNQLHRSQEEEGTQ-RKALEAQNEIHTKEKEKLID 1280
                L+E+ E +K +LE+         +L   +E+E  + +KALE + + H   + ++ D
Sbjct: 1144 ----LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH---EAQIQD 1196

Query: 1281 KIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRV-------IKK 1333
              Q    A + L +Q E     K N  +    L  +N++L  E+ +  +V        KK
Sbjct: 1197 MRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKK 1256

Query: 1334 LQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGV 1387
            L  QV+ L   + + + +      K        K ++E   +  L+ + + +G+
Sbjct: 1257 LDAQVQELHAKVSEGDRLRVELAEK------ASKLQNELDNVSTLLEEAEKKGI 1304



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 106/508 (20%), Positives = 213/508 (41%), Gaps = 48/508 (9%)

Query: 886  QLTYRVQRLQKKLEDQNKENHGLVEKLTS---LAALRAGDVE-KIQKLEAELEKAATHRR 941
            Q+   +++ QKK +    E   +  +       A   A + E K   L   LE+A   + 
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 942  NYEEKGKRYR----------DAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMD 991
             +E + K+ R          D V + + +L+K    LE Q E+++ +L+E  +EL+   D
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560

Query: 992  ---------NLTKQLFD------DVQKEERQRMLLE--KSFELKTQDYEKQIQSLKEEIK 1034
                        K  F+      D Q EE++R+L++  +  E + +D  KQ        K
Sbjct: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620

Query: 1035 ALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQS 1094
             ++ +   L+  +E  +   D +  ++ +L  Q+K   ++++E+E  +A + ++    + 
Sbjct: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMK---DYQRELEEARASRDEIFAQSKE 1677

Query: 1095 QKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESH 1154
             +++++   +EI +   E    E  R     E  E  +E          L    R LE+ 
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1737

Query: 1155 FQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDF 1214
                ++  E E E  N ++++     +  +K   + + +N  +  E +     +      
Sbjct: 1738 IAQLEE--ELEEEQSNMELLN-----DRFRKTTLQVDTLNAELAAERSAAQKSDNARQQL 1790

Query: 1215 KQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKE 1274
            ++Q  EL+ + Q+LE  +  + +     LE    QL    E+E  +R A         K+
Sbjct: 1791 ERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKK 1850

Query: 1275 KEKLIDKIQEMQEASDHLKKQFE-TESEVKCNFRQ------EASRLTLENRDLEEELDMK 1327
             +++  ++++ +  +D  K+Q E   + +K   RQ      EA+R     R L+ ELD  
Sbjct: 1851 LKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDA 1910

Query: 1328 DRVIKKLQDQVKTLSKTIGKANDVHSSS 1355
                + L  +V TL   + +   +  SS
Sbjct: 1911 TEANEGLSREVSTLKNRLRRGGPISFSS 1938



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 127/565 (22%), Positives = 248/565 (43%), Gaps = 82/565 (14%)

Query: 851  RKMLEEHKAVILQKYARAWLARRRFQSIR--RFVLNIQLTYRVQRLQKKLEDQNKENHGL 908
            +K++E+  A    + A      +    IR  + V+   L  R+++ +K  ++  K    L
Sbjct: 1001 KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL 1060

Query: 909  VEKLTSL----AALRAG-DVEKIQ--KLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKL 961
              + T L    A L+A  D  K+Q  K E EL+ A     +           V E  A++
Sbjct: 1061 DGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQI 1120

Query: 962  QKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQ----------KEERQRMLL 1011
             +   + E++K   + K +++  +L E+++ L  +L D +           K E++   L
Sbjct: 1121 AELQEDFESEKAS-RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179

Query: 1012 EKSFELKTQDYEKQIQSLKEE----IKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQ 1067
            +K+ E +T+++E QIQ +++     ++ L ++  Q +           GL+ +   L+ +
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACE 1239

Query: 1068 VKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLS--V 1125
            VK + + + E E          K + +Q +E+  K+SE  +  +E   + +  S+L   +
Sbjct: 1240 VKVLQQVKAESE-------HKRKKLDAQVQELHAKVSEGDRLRVE---LAEKASKLQNEL 1289

Query: 1126 EDLEHLNEDGELWFAYEGLK--KATRVLESHFQSQKDCYEKEIEA---LNFKVVHLSQEI 1180
            +++  L E+ E     +G+K  K    LES  Q  ++  ++E      L+ ++  L +E 
Sbjct: 1290 DNVSTLLEEAEK----KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEK 1345

Query: 1181 NHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMK 1240
            N LQ+   EE +  +++  +V  L S          Q+++ +K+  D ++   E  E+ K
Sbjct: 1346 NSLQEQQEEEEEARKNLEKQVLALQS----------QLADTKKKVDD-DLGTIESLEEAK 1394

Query: 1241 GKLEELSNQLHRSQEEEGTQRKALE-AQNEIHTKEKEKLIDKIQEMQEASDHLKKQ---- 1295
             KL + +  L +  EE+      LE  +N +  +  +  +D   + Q AS+  KKQ    
Sbjct: 1395 KKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD 1454

Query: 1296 --FETESEVKCNFRQEASRLTLENRD-----------LEEELDMK---DRVIKKLQDQVK 1339
                 E  +   + +E  R   E R+           LEE L+ K   +R  K+L+  ++
Sbjct: 1455 QLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADME 1514

Query: 1340 TLSKT---IGKANDVHSSSGPKEYL 1361
             L  +   +GK  +VH     K  L
Sbjct: 1515 DLMSSKDDVGK--NVHELEKSKRAL 1537



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 93/498 (18%), Positives = 221/498 (44%), Gaps = 82/498 (16%)

Query: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY 950
            V  L+K LE++ K +   ++ +      R      +++L  +LE+A           KR+
Sbjct: 1176 VAELKKALEEETKNHEAQIQDM------RQRHATALEELSEQLEQA-----------KRF 1218

Query: 951  RDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRM- 1009
            +  +E+    L+  N EL  + + +Q +++ ++E  ++K+D   ++L   V + +R R+ 
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQ-QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277

Query: 1010 LLEKSFELKTQ---------DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAE 1060
            L EK+ +L+ +         + EK+     ++  +L+ +    Q L++ E      L + 
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337

Query: 1061 VARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVR 1120
            + +L ++  ++ E ++E E  +A+K ++EK V + + ++ +   ++   L     +E+ +
Sbjct: 1338 IRQLEEEKNSLQEQQEEEE--EARK-NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAK 1394

Query: 1121 SRLSVEDLEHLNED-GELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQE 1179
             +L ++D E L++   E   AY+ L+K            K+  ++E++ L   + H  Q 
Sbjct: 1395 KKL-LKDAEALSQRLEEKALAYDKLEKT-----------KNRLQQELDDLTVDLDHQRQV 1442

Query: 1180 INHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKM 1239
             ++L+K                             +++  +L  +++ +  R  E+ ++ 
Sbjct: 1443 ASNLEKK----------------------------QKKFDQLLAEEKSISARYAEERDRA 1474

Query: 1240 KGKLEELSNQ---LHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQF 1296
            + +  E   +   L R+ EE      ALEA+ E   + K+   D ++++  + D + K  
Sbjct: 1475 EAEAREKETKALSLARALEE------ALEAKEEFERQNKQLRAD-MEDLMSSKDDVGKNV 1527

Query: 1297 ETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSG 1356
                + K    Q+   +  +  +LE+EL   +    +L+  ++ +     +         
Sbjct: 1528 HELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN 1587

Query: 1357 PKEYLGMLQYKREDEAKL 1374
             ++   +++  RE EA+L
Sbjct: 1588 EEKKRLLIKQVRELEAEL 1605



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 101/493 (20%), Positives = 206/493 (41%), Gaps = 69/493 (13%)

Query: 889  YRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKI------QKLEAELEK-AATHRR 941
            + +++ ++ LE Q +E    +E+L     L+A +  K+      Q ++A+ E+   T   
Sbjct: 1528 HELEKSKRALEQQVEEMRTQLEELED--ELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585

Query: 942  NYEEKGKRYRDAVEEKLAKLQKHNSE-----LETQKEQIQLK-LQEKTEELKEKMDNLTK 995
              EEK +     V E  A+L+    +        +K +I LK L+ + E   +  D + K
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645

Query: 996  QL------FDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEG 1049
            QL        D Q+E  +          ++++ EK+++SL+ EI  L++E    +     
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705

Query: 1050 EHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQ 1109
                 D L  E+   +     + + ++ +E   AQ  +  +  QS    + ++  + T Q
Sbjct: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765

Query: 1110 LLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQ----SQKDCYEKE 1165
                  ++ + + L+ E       D     A + L++  + L++  Q    + K  ++  
Sbjct: 1766 ------VDTLNAELAAERSAAQKSDN----ARQQLERQNKELKAKLQELEGAVKSKFKAT 1815

Query: 1166 IEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQK 1225
            I AL  K+  L ++   L++  +E    N+ +R    +L    M + D        E++ 
Sbjct: 1816 ISALEAKIGQLEEQ---LEQEAKERAAANKLVRRTEKKLKEIFMQVED--------ERRH 1864

Query: 1226 QDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEM 1285
             D   +  EQ EK   ++++L  QL  + EEE T+  A           + KL  ++ + 
Sbjct: 1865 AD---QYKEQMEKANARMKQLKRQLEEA-EEEATRANA----------SRRKLQRELDDA 1910

Query: 1286 QEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
             EA++ L ++  T   +K   R+        +R    +L ++   ++   D       T 
Sbjct: 1911 TEANEGLSREVST---LKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDD------TE 1961

Query: 1346 GKANDVHSSSGPK 1358
             K +DV+ +  P+
Sbjct: 1962 SKTSDVNETQPPQ 1974



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 83/386 (21%), Positives = 159/386 (41%), Gaps = 56/386 (14%)

Query: 775  KFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMAT 834
            K +RE  A L  ++  R      K    + LK+  A I      R  +++ L +L     
Sbjct: 1596 KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKL----- 1650

Query: 835  ITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRL 894
               QA  +       Y++ LEE +A   + +A++  + ++ +S+   +L +Q        
Sbjct: 1651 ---QAQMKD------YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701

Query: 895  QKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAV 954
             ++  +Q ++   L +++T+ A+ ++  +++ ++LEA + +        +   +   D  
Sbjct: 1702 ARRHAEQERDE--LADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRF 1759

Query: 955  EEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS 1014
             +   ++   N+EL  ++   Q            K DN  +QL       ERQ     K 
Sbjct: 1760 RKTTLQVDTLNAELAAERSAAQ------------KSDNARQQL-------ERQ----NKE 1796

Query: 1015 FELKTQDYEKQIQS-LKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISE 1073
             + K Q+ E  ++S  K  I AL+ +  QL+  +E E          V R  K++K I  
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI-- 1854

Query: 1074 FEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL---LESYDIEDVRSRLSVEDLEH 1130
                       +++ E+    Q +E  EK +   KQL   LE  + E  R+  S   L+ 
Sbjct: 1855 ---------FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905

Query: 1131 LNEDGELWFAYEGLKKATRVLESHFQ 1156
              +D     A EGL +    L++  +
Sbjct: 1906 ELDDAT--EANEGLSREVSTLKNRLR 1929


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  554 bits (1427), Expect = e-157
 Identities = 353/989 (35%), Positives = 533/989 (53%), Gaps = 86/989 (8%)

Query: 19  EEVWKSAEIAKDYRVGDKVLRLLLEDGT-------ELDYSVNPESLPPLR--NPDILVGE 69
           + VW    + +++ V    +  L + G        + ++ ++P++   ++  +P  + G 
Sbjct: 8   DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67

Query: 70  NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129
            D+  L  L+E  +L NL IR+ +  LIYTY+G ILVA+NPY+ L IY    I  Y+ + 
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDH-LIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126

Query: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189
           +G+M PHIFA+A+  Y  M RN+R+Q  I+SGESGAGKT S +  +++ A +S  G ++ 
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSW 184

Query: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249
           +E +VL + PI EA GNAKT RNDNSSRFGKY +I F+++  I GA +  YLLEKSRV  
Sbjct: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244

Query: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT 309
           Q+ +ERNYH+FY +     + + K L LG A ++NY  MG     EG  D  E    +  
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304

Query: 310 FTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE--DDSHLKVFCELLGLESG 367
             +L F +    ++ K+LAAILHLGN+Q  A   E     E      L     LL +   
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364

Query: 368 RVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL-----Q 422
            +   L +R ++T  ETV  P++R QA++ RDA  K IY  LF +IV++IN A+     Q
Sbjct: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424

Query: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                   IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F  HVFKLEQEEY  E I W
Sbjct: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484

Query: 483 TLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541
             I+F DNQ  +D+I  K M I+ L+DEE   P GTD   L KL N+    N  +  P+ 
Sbjct: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKL-NSQHKLNANYIPPKN 543

Query: 542 SN-TSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF 600
           ++ T F I HFA  V Y+ +GFLEKNRDT++  +++++ +S+       FQ         
Sbjct: 544 NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------- 594

Query: 601 GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE 660
                   A   +   ++    T+ S+F+ SL LLM TL A  P +VRCIKPN+ K P  
Sbjct: 595 --------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646

Query: 661 FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILM--TKQELSFSDKKEVCK 718
           FD    V+QLR  G++ETIRI    YP R++++EF  RY +L+   K      D +  C+
Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706

Query: 719 VVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLR 778
            +   ++   + +Q GKTKIF +      LE  R   +    +++QK +RG+  R  FL+
Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766

Query: 779 ERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQ 838
            + AA +IQ+++RG    RK    + L      + +Q   R   +   Y+L R   I  Q
Sbjct: 767 LKNAATLIQRHWRG-HNCRKNYGLMRL----GFLRLQALHRSRKLHQQYRLARQRIIQFQ 821

Query: 839 AYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898
           A  R +L R+ +R  L     + +Q YAR  +ARR  Q +R      +  +R++  + +L
Sbjct: 822 ARCRAYLVRKAFRHRL--WAVLTVQAYARGMIARRLHQRLR-----AEYLWRLEAEKMRL 874

Query: 899 EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKL 958
            ++ K                             L K  + ++  EE  +++    +E+L
Sbjct: 875 AEEEK-----------------------------LRKEMSAKKAKEEAERKH----QERL 901

Query: 959 AKLQKHNSELETQKEQIQLKLQEKTEELK 987
           A+L + ++E E ++++   + +E  E+++
Sbjct: 902 AQLAREDAERELKEKEAARRKKELLEQME 930


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  554 bits (1427), Expect = e-157
 Identities = 353/989 (35%), Positives = 533/989 (53%), Gaps = 86/989 (8%)

Query: 19  EEVWKSAEIAKDYRVGDKVLRLLLEDGT-------ELDYSVNPESLPPLR--NPDILVGE 69
           + VW    + +++ V    +  L + G        + ++ ++P++   ++  +P  + G 
Sbjct: 8   DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67

Query: 70  NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129
            D+  L  L+E  +L NL IR+ +  LIYTY+G ILVA+NPY+ L IY    I  Y+ + 
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDH-LIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126

Query: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189
           +G+M PHIFA+A+  Y  M RN+R+Q  I+SGESGAGKT S +  +++ A +S  G ++ 
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSW 184

Query: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249
           +E +VL + PI EA GNAKT RNDNSSRFGKY +I F+++  I GA +  YLLEKSRV  
Sbjct: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244

Query: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT 309
           Q+ +ERNYH+FY +     + + K L LG A ++NY  MG     EG  D  E    +  
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304

Query: 310 FTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE--DDSHLKVFCELLGLESG 367
             +L F +    ++ K+LAAILHLGN+Q  A   E     E      L     LL +   
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364

Query: 368 RVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL-----Q 422
            +   L +R ++T  ETV  P++R QA++ RDA  K IY  LF +IV++IN A+     Q
Sbjct: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424

Query: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                   IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F  HVFKLEQEEY  E I W
Sbjct: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484

Query: 483 TLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541
             I+F DNQ  +D+I  K M I+ L+DEE   P GTD   L KL N+    N  +  P+ 
Sbjct: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKL-NSQHKLNANYIPPKN 543

Query: 542 SN-TSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF 600
           ++ T F I HFA  V Y+ +GFLEKNRDT++  +++++ +S+       FQ         
Sbjct: 544 NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------- 594

Query: 601 GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE 660
                   A   +   ++    T+ S+F+ SL LLM TL A  P +VRCIKPN+ K P  
Sbjct: 595 --------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646

Query: 661 FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILM--TKQELSFSDKKEVCK 718
           FD    V+QLR  G++ETIRI    YP R++++EF  RY +L+   K      D +  C+
Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706

Query: 719 VVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLR 778
            +   ++   + +Q GKTKIF +      LE  R   +    +++QK +RG+  R  FL+
Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766

Query: 779 ERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQ 838
            + AA +IQ+++RG    RK    + L      + +Q   R   +   Y+L R   I  Q
Sbjct: 767 LKNAATLIQRHWRG-HNCRKNYGLMRL----GFLRLQALHRSRKLHQQYRLARQRIIQFQ 821

Query: 839 AYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898
           A  R +L R+ +R  L     + +Q YAR  +ARR  Q +R      +  +R++  + +L
Sbjct: 822 ARCRAYLVRKAFRHRL--WAVLTVQAYARGMIARRLHQRLR-----AEYLWRLEAEKMRL 874

Query: 899 EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKL 958
            ++ K                             L K  + ++  EE  +++    +E+L
Sbjct: 875 AEEEK-----------------------------LRKEMSAKKAKEEAERKH----QERL 901

Query: 959 AKLQKHNSELETQKEQIQLKLQEKTEELK 987
           A+L + ++E E ++++   + +E  E+++
Sbjct: 902 AQLAREDAERELKEKEAARRKKELLEQME 930


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  554 bits (1427), Expect = e-157
 Identities = 353/989 (35%), Positives = 533/989 (53%), Gaps = 86/989 (8%)

Query: 19  EEVWKSAEIAKDYRVGDKVLRLLLEDGT-------ELDYSVNPESLPPLR--NPDILVGE 69
           + VW    + +++ V    +  L + G        + ++ ++P++   ++  +P  + G 
Sbjct: 8   DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67

Query: 70  NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129
            D+  L  L+E  +L NL IR+ +  LIYTY+G ILVA+NPY+ L IY    I  Y+ + 
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDH-LIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126

Query: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189
           +G+M PHIFA+A+  Y  M RN+R+Q  I+SGESGAGKT S +  +++ A +S  G ++ 
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSW 184

Query: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249
           +E +VL + PI EA GNAKT RNDNSSRFGKY +I F+++  I GA +  YLLEKSRV  
Sbjct: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244

Query: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT 309
           Q+ +ERNYH+FY +     + + K L LG A ++NY  MG     EG  D  E    +  
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304

Query: 310 FTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE--DDSHLKVFCELLGLESG 367
             +L F +    ++ K+LAAILHLGN+Q  A   E     E      L     LL +   
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364

Query: 368 RVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL-----Q 422
            +   L +R ++T  ETV  P++R QA++ RDA  K IY  LF +IV++IN A+     Q
Sbjct: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424

Query: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
                   IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F  HVFKLEQEEY  E I W
Sbjct: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484

Query: 483 TLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541
             I+F DNQ  +D+I  K M I+ L+DEE   P GTD   L KL N+    N  +  P+ 
Sbjct: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKL-NSQHKLNANYIPPKN 543

Query: 542 SN-TSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF 600
           ++ T F I HFA  V Y+ +GFLEKNRDT++  +++++ +S+       FQ         
Sbjct: 544 NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------- 594

Query: 601 GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE 660
                   A   +   ++    T+ S+F+ SL LLM TL A  P +VRCIKPN+ K P  
Sbjct: 595 --------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646

Query: 661 FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILM--TKQELSFSDKKEVCK 718
           FD    V+QLR  G++ETIRI    YP R++++EF  RY +L+   K      D +  C+
Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706

Query: 719 VVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLR 778
            +   ++   + +Q GKTKIF +      LE  R   +    +++QK +RG+  R  FL+
Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766

Query: 779 ERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQ 838
            + AA +IQ+++RG    RK    + L      + +Q   R   +   Y+L R   I  Q
Sbjct: 767 LKNAATLIQRHWRG-HNCRKNYGLMRL----GFLRLQALHRSRKLHQQYRLARQRIIQFQ 821

Query: 839 AYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898
           A  R +L R+ +R  L     + +Q YAR  +ARR  Q +R      +  +R++  + +L
Sbjct: 822 ARCRAYLVRKAFRHRL--WAVLTVQAYARGMIARRLHQRLR-----AEYLWRLEAEKMRL 874

Query: 899 EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKL 958
            ++ K                             L K  + ++  EE  +++    +E+L
Sbjct: 875 AEEEK-----------------------------LRKEMSAKKAKEEAERKH----QERL 901

Query: 959 AKLQKHNSELETQKEQIQLKLQEKTEELK 987
           A+L + ++E E ++++   + +E  E+++
Sbjct: 902 AQLAREDAERELKEKEAARRKKELLEQME 930


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  552 bits (1423), Expect = e-157
 Identities = 336/888 (37%), Positives = 498/888 (56%), Gaps = 39/888 (4%)

Query: 39  RLLLEDGTELDYSVNPESLPPLR--NPDILVGENDLTALSYLHEPAVLHNLRIRFAESKL 96
           ++L+ED    ++ +  E    L   +P+ + G +D+  L  L+E  ++HNL IR+ + K 
Sbjct: 35  KVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHK- 93

Query: 97  IYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQS 156
           IYTY+G ILVA+NP++ LP+Y    +  Y  ++MG++ PH+FA+A   Y  M RN R+Q 
Sbjct: 94  IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQC 153

Query: 157 IIVSGESGAGKTVSARYAMRYFATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSS 216
            I+SGESGAGKT + +  +++ AT+S  G ++ +E +VL +NPI EA GNAKT RNDNSS
Sbjct: 154 CIISGESGAGKTETTKLILQFLATIS--GQHSWIEQQVLEANPILEAFGNAKTIRNDNSS 211

Query: 217 RFGKYTEISFDEQNQIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLK 276
           RFGKY +I F+    I GA +  +LLEKSRV  Q+  ERNYHIFY +       + + L 
Sbjct: 212 RFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLS 271

Query: 277 LGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNV 336
           LG+  E++Y  MG  T  EG+ND  +    +    +L F +    DV K+LAAILHLGNV
Sbjct: 272 LGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNV 331

Query: 337 QITAVGNERSSVSE--DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQA 394
              A   E    S+  +        +LL ++   +   L    I+   E V + +   QA
Sbjct: 332 GFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQA 391

Query: 395 VNARDALAKKIYAHLFDFIVERINQAL-----QFSGKQHTFIGVLDIYGFETFDVNSFEQ 449
            + RDA  K IY HLF +IV++IN A+     Q        IG+LDI+GFE F+ NSFEQ
Sbjct: 392 ADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQ 451

Query: 450 FCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAK-MGILELLD 508
            CIN+ANE LQQ F  HVF +EQEEY  E+I W  I + DN+P +DL+  K M I+ LLD
Sbjct: 452 LCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLD 511

Query: 509 EECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRD 568
           EE   P GTD   LQKL +   N     +   + +  F I HFA +V Y+ EGFLEKNRD
Sbjct: 512 EESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRD 571

Query: 569 TVYDMLVEILRASKFHLCANFFQ-ENPTPPSPFGSMITVKSAKQVIKPNSKHFR-TTVGS 626
            +   ++ ++ +SK       F  E        G++   K+   + K    + R +T+GS
Sbjct: 572 VLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGS 631

Query: 627 KFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSY 686
           +F+ SL  LM+ L    P+++RCIKPN+ K P  FD +  ++QLR  G++ET+ I    +
Sbjct: 632 QFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGF 691

Query: 687 PSRWTYIEFYSRYGILM-TKQELSFSDK-KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQ 744
           P R+T+ EF  R+G+L+     +    K +++   +    ++    ++ GKTKIF R  Q
Sbjct: 692 PIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ 751

Query: 745 VAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVR------- 797
              LE  R   L ++ + +QK +RG+  RK+FLR+RRAA+ +Q ++RG    R       
Sbjct: 752 DTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILV 811

Query: 798 --KAITAVALKEAWA---------AIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLA 846
             + + A+A  +  A          + +Q  CRGYLVR   Q  R A + +QA++RG  A
Sbjct: 812 GFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAA 871

Query: 847 RRRYRKMLEEHKAVIL---QKYARAWLARRRFQSIRRFVLNIQLTYRV 891
           RR +++       VI    QK   A  A++R +SI   V + ++  +V
Sbjct: 872 RRNFQQRKANAPLVIPAEGQKSQGALPAKKR-RSIYDTVTDTEMVEKV 918


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score =  550 bits (1417), Expect = e-156
 Identities = 436/1406 (31%), Positives = 688/1406 (48%), Gaps = 125/1406 (8%)

Query: 7    YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65
            +T    VW+P     +++A +  +   G++   + L E G  L     P       NP  
Sbjct: 50   WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103

Query: 66   LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125
                 D+  L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYKQLPIY +AI+  Y
Sbjct: 104  FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162

Query: 126  SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKS- 184
             G+   ++ PH++AV E AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S 
Sbjct: 163  RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222

Query: 185  ------GSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
                  G    +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ 
Sbjct: 223  KGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIE 282

Query: 239  TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
            TYLLEKSR + Q+++E ++HIFYQL   A +     L L     + +   G ++      
Sbjct: 283  TYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--SPGQ 340

Query: 299  DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVF 358
            +R    ET ++  +LGF  +  + + ++++A+L  GN+ +    N   +   D++  +  
Sbjct: 341  ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKL 400

Query: 359  CELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERIN 418
            C LLGL     ++ L   +I    + V K  T+ QA  A +ALAK  Y  LF ++V R+N
Sbjct: 401  CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLN 460

Query: 419  QALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 477
            +AL  S +Q  +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN  +F LEQEEY +
Sbjct: 461  RALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 520

Query: 478  EDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKLYNNFVNRN 533
            E IPWT +DF  D QP IDLIE      G+L LLDEEC  P  TD+++++K+       +
Sbjct: 521  EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE-QGGH 579

Query: 534  PLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQ 591
            P F++PR       F + H+A KV+YK   +L KN D + D +  +L  S   L A  ++
Sbjct: 580  PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 639

Query: 592  ENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIK 651
            +          + ++       +P    FR TVG  ++ SL  LM TL+ T P +VRCI 
Sbjct: 640  DVEGIVG-LEQVSSLGDGPPGGRPRRGMFR-TVGQLYKESLSRLMATLSNTNPSFVRCIV 697

Query: 652  PNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSF 710
            PN EK   + + + ++ QLR  GVLE IRI  Q +P+R  + EF  RY IL        F
Sbjct: 698  PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGF 757

Query: 711  SDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGW 770
             D K+ C+ ++  L  D N Y+ G++KIFFRAG +A LE+ R  K+    V  Q   RG+
Sbjct: 758  MDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGY 817

Query: 771  LQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830
            L R+ F + ++           QQ+              A  ++Q++C  YL    +Q  
Sbjct: 818  LARRAFQKRQQ-----------QQS--------------ALRVMQRNCAAYLKLRHWQWW 852

Query: 831  RMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR 890
            R+ T       +  L   R  ++L+  +A  LQK                  L  Q    
Sbjct: 853  RLFTKV-----KPLLQVTRQDEVLQA-RAQELQKVQE---------------LQQQSARE 891

Query: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVE-----KIQKLEAELEKAATHRRNYEE 945
            V  LQ ++    +E   L E+L + A L A   E       +K E EL  +    R  EE
Sbjct: 892  VGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEE 951

Query: 946  KGKRYRDAVEEKLAKLQKHNSELETQKE-----QIQLKLQEKTEELK-EKMDNLTKQLFD 999
            +    +   E+K  +LQ+H  ELE   E     + +L+L++ T E K +K +     L D
Sbjct: 952  EECSRQMQTEKK--RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1009

Query: 1000 DVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKA 1059
               K  ++R LLE     +  ++  Q    +E++K+L   +++ +  +       D L+ 
Sbjct: 1010 QNSKLSKERKLLED----RLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD---MEDRLRK 1062

Query: 1060 EVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDV 1119
            E     +  K     + E   LQ Q ++ ++  +  + ++  K  E+   L  + D    
Sbjct: 1063 EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1122

Query: 1120 RSRLSVEDLEHLNE-DGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHL-- 1176
            R++L    L+ L E    L  A E L ++ RV  +  + Q+    +E+EAL  ++     
Sbjct: 1123 RAQL----LKSLREAQAALAEAQEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLD 1177

Query: 1177 ------------SQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQ 1224
                         QE+  L+K   EE  I+E+   E+ +       + +  +Q+ +  + 
Sbjct: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ--RHGQALGELAEQLEQARRG 1235

Query: 1225 KQDLE-IRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIH------TKEKEK 1277
            K   E  RL  +AE  + + E  S Q  R + E+  +R  L+ Q E+        + + +
Sbjct: 1236 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ-EVQGRAGDGERARAE 1294

Query: 1278 LIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQ 1337
              +K+Q  Q   +++               +E S    +  D +E L  + R    L  +
Sbjct: 1295 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1354

Query: 1338 VKTL-SKTIGKANDVHSSSGPKEYLG 1362
            V+ + ++  G    +   +  +E  G
Sbjct: 1355 VRAMEAEAAGLREQLEEEAAARERAG 1380



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903
            +R++ ++L E KA +L+        R   +   R    + LT  +   Q  +++LE QN+
Sbjct: 1467 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1524

Query: 904  ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
                 +E L S        V ++++     E+AA   R    + +    A E+   +L+ 
Sbjct: 1525 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1584

Query: 964  HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020
                L+TQ E+    LQ + E  +E+   L KQL D +V+++E  +QR L   +      
Sbjct: 1585 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1635

Query: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
               K+++   EE+KA      Q             G +  V +L K    + E  +E+E 
Sbjct: 1636 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1680

Query: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137
             +  +    + + SQ RE  +++  +  ++L   E     D   R + +D + + ++   
Sbjct: 1681 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1733

Query: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
              A   L KA  +LE            E   L  ++  L +E+   Q      ND    +
Sbjct: 1734 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779

Query: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249
              +V  LT+E      F  +      +LE+Q Q+L  RL E+      + K  +  L ++
Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839

Query: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305
            L +++E+ E   R+ + +   +   EK  ++++ +++E +  +D L+ Q E  +  VK  
Sbjct: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899

Query: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
             RQ      EASR     R L+ EL+      + +  +V TL
Sbjct: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1941



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%)

Query: 876  QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933
            Q  R   L  QL  + + LQ  L     E     + L SL   +A   E  + LE+E   
Sbjct: 1091 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1150

Query: 934  -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983
              KA   RR+  E+ +  R  +E+ L      Q+  S+ E +  +++  L+E+T      
Sbjct: 1151 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1210

Query: 984  -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039
             +EL+++      +L + +++  R +   EK+    E +  +   ++ SL+   +  +  
Sbjct: 1211 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1270

Query: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081
            + +L+  L E +    DG +A      K  +  +E E                 KE+   
Sbjct: 1271 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330

Query: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141
            +AQ  D ++ +Q    E R K++  ++      +   +R +L  E         EL  A 
Sbjct: 1331 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1387

Query: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190
              L +  R        LE+  ++++    +E EAL  ++   ++ ++ L++    L +E 
Sbjct: 1388 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1446

Query: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250
            +D    +  +   +++       F Q ++E EK      +   E+AE    + E  +  L
Sbjct: 1447 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1505

Query: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
             R+ EEE   R+ LE QN     E E L+    ++ ++   L++             Q A
Sbjct: 1506 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1558

Query: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
            + L  +  +LE+EL   +    +L+  V+ L
Sbjct: 1559 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1589



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%)

Query: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084
            Q+    E ++A   E  ++Q L +        L+  VA+L ++   ++E  +    L A+
Sbjct: 863  QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 922

Query: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
              +    + ++K+E+   +SE+  ++ E    S  ++  + RL     +H+ E      A
Sbjct: 923  AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 978

Query: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
             EG ++  ++ +   +++   +E+++  L  +   LS+E   L+    E    +     E
Sbjct: 979  EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1035

Query: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
              ++ S N +   ++  I+++E + +  E +  ++ EK+K +L+  S++L     E+  Q
Sbjct: 1036 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1092

Query: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
            ++A E + ++  KE        +E+Q A    + +    +++  + R+  + L     DL
Sbjct: 1093 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144

Query: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371
            E E   + +  K+ +D  + L    G+  D   S+  ++    L+ KRE E
Sbjct: 1145 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1192


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score =  549 bits (1415), Expect = e-156
 Identities = 446/1446 (30%), Positives = 696/1446 (48%), Gaps = 164/1446 (11%)

Query: 7    YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65
            +T    VW+P     +++A +  +   G++   + L E G  L     P       NP  
Sbjct: 50   WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103

Query: 66   LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125
                 D+  L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYKQLPIY +AI+  Y
Sbjct: 104  FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162

Query: 126  SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185
             G+   ++ PH++AV E AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S 
Sbjct: 163  RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222

Query: 186  ---------------SNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQN 230
                           S   +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD   
Sbjct: 223  KGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAG 282

Query: 231  QIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGG 290
             I+GAN+ TYLLEKSR + Q+++E ++HIFYQL   A +     L L     + +   G 
Sbjct: 283  YIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGP 342

Query: 291  NTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE 350
            ++      +R    ET ++  +LGF  +  + + ++++A+L  GN+ +    N   +   
Sbjct: 343  SS--SPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMP 400

Query: 351  DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLF 410
            D++  +  C LLGL     ++ L   +I    + V K  T+ QA  A +ALAK  Y  LF
Sbjct: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLF 460

Query: 411  DFIVERINQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFK 469
             ++V R+N+AL  S +Q  +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN  +F 
Sbjct: 461  RWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFV 520

Query: 470  LEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKL 525
            LEQEEY +E IPWT +DF  D QP IDLIE      G+L LLDEEC  P  TD+++++K+
Sbjct: 521  LEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKV 580

Query: 526  YNNFVNRNPLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKF 583
                   +P F++PR       F + H+A KV+YK   +L KN D + D +  +L  S  
Sbjct: 581  AQE-QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639

Query: 584  HLCANFFQE-----------NPTPPSPFGSMITVKSA------------KQVI------- 613
             L A  +++              PPSP GS     SA            +QV        
Sbjct: 640  RLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPP 699

Query: 614  --KPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLR 671
              +P    FR TVG  ++ SL  LM TL+ T P +VRCI PN EK   + + + ++ QLR
Sbjct: 700  GGRPRRGMFR-TVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLR 758

Query: 672  ACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKKEVCKVVLHRLIQDSNQ 730
              GVLE IRI  Q +P+R  + EF  RY IL        F D K+ C+ ++  L  D N 
Sbjct: 759  CNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNL 818

Query: 731  YQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYF 790
            Y+ G++KIFFRAG +A LE+ R  K+    V  Q   RG+L R+ F + ++         
Sbjct: 819  YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQ--------- 869

Query: 791  RGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRY 850
              QQ+              A  ++Q++C  YL    +Q  R+ T       +  L   R 
Sbjct: 870  --QQS--------------ALRVMQRNCAAYLKLRHWQWWRLFTKV-----KPLLQVTRQ 908

Query: 851  RKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVE 910
             ++L+  +A  LQK                  L  Q    V  LQ ++    +E   L E
Sbjct: 909  DEVLQA-RAQELQKVQE---------------LQQQSAREVGELQGRVAQLEEERARLAE 952

Query: 911  KLTSLAALRAGDVE-----KIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHN 965
            +L + A L A   E       +K E EL  +    R  EE+    +   E+K  +LQ+H 
Sbjct: 953  QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK--RLQQHI 1010

Query: 966  SELETQKE-----QIQLKLQEKTEELK-EKMDNLTKQLFDDVQKEERQRMLLEKSFELKT 1019
             ELE   E     + +L+L++ T E K +K +     L D   K  ++R LLE     + 
Sbjct: 1011 QELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED----RL 1066

Query: 1020 QDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079
             ++  Q    +E++K+L   +++ +  +       D L+ E     +  K     + E  
Sbjct: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIAD---MEDRLRKEEKGRQELEKLKRRLDGESS 1123

Query: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNE-DGELW 1138
             LQ Q ++ ++  +  + ++  K  E+   L  + D    R++L    L+ L E    L 
Sbjct: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL----LKSLREAQAALA 1179

Query: 1139 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHL--------------SQEINHLQ 1184
             A E L ++ RV  +  + Q+    +E+EAL  ++                  QE+  L+
Sbjct: 1180 EAQEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238

Query: 1185 KLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLE-IRLNEQAEKMKGKL 1243
            K   EE  I+E+   E+ +       + +  +Q+ +  + K   E  RL  +AE  + + 
Sbjct: 1239 KTLEEETRIHEAAVQELRQ--RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296

Query: 1244 EELSNQLHRSQEEEGTQRKALEAQNEIH------TKEKEKLIDKIQEMQEASDHLKKQFE 1297
            E  S Q  R + E+  +R  L+ Q E+        + + +  +K+Q  Q   +++     
Sbjct: 1297 ELSSLQTARQEGEQRRRRLELQLQ-EVQGRAGDGERARAEAAEKLQRAQAELENVSGALN 1355

Query: 1298 TESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTL-SKTIGKANDVHSSSG 1356
                      +E S    +  D +E L  + R    L  +V+ + ++  G    +   + 
Sbjct: 1356 EAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA 1415

Query: 1357 PKEYLG 1362
             +E  G
Sbjct: 1416 ARERAG 1421



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903
            +R++ ++L E KA +L+        R   +   R    + LT  +   Q  +++LE QN+
Sbjct: 1508 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1565

Query: 904  ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
                 +E L S        V ++++     E+AA   R    + +    A E+   +L+ 
Sbjct: 1566 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1625

Query: 964  HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020
                L+TQ E+    LQ + E  +E+   L KQL D +V+++E  +QR L   +      
Sbjct: 1626 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1676

Query: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
               K+++   EE+KA      Q             G +  V +L K    + E  +E+E 
Sbjct: 1677 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1721

Query: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137
             +  +    + + SQ RE  +++  +  ++L   E     D   R + +D + + ++   
Sbjct: 1722 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1774

Query: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
              A   L KA  +LE            E   L  ++  L +E+   Q      ND    +
Sbjct: 1775 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1820

Query: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249
              +V  LT+E      F  +      +LE+Q Q+L  RL E+      + K  +  L ++
Sbjct: 1821 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1880

Query: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305
            L +++E+ E   R+ + +   +   EK  ++++ +++E +  +D L+ Q E  +  VK  
Sbjct: 1881 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1940

Query: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
             RQ      EASR     R L+ EL+      + +  +V TL
Sbjct: 1941 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1982



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%)

Query: 876  QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933
            Q  R   L  QL  + + LQ  L     E     + L SL   +A   E  + LE+E   
Sbjct: 1132 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191

Query: 934  -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983
              KA   RR+  E+ +  R  +E+ L      Q+  S+ E +  +++  L+E+T      
Sbjct: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251

Query: 984  -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039
             +EL+++      +L + +++  R +   EK+    E +  +   ++ SL+   +  +  
Sbjct: 1252 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1311

Query: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081
            + +L+  L E +    DG +A      K  +  +E E                 KE+   
Sbjct: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371

Query: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141
            +AQ  D ++ +Q    E R K++  ++      +   +R +L  E         EL  A 
Sbjct: 1372 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1428

Query: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190
              L +  R        LE+  ++++    +E EAL  ++   ++ ++ L++    L +E 
Sbjct: 1429 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1487

Query: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250
            +D    +  +   +++       F Q ++E EK      +   E+AE    + E  +  L
Sbjct: 1488 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1546

Query: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
             R+ EEE   R+ LE QN     E E L+    ++ ++   L++             Q A
Sbjct: 1547 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1599

Query: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
            + L  +  +LE+EL   +    +L+  V+ L
Sbjct: 1600 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1630



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%)

Query: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084
            Q+    E ++A   E  ++Q L +        L+  VA+L ++   ++E  +    L A+
Sbjct: 904  QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 963

Query: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
              +    + ++K+E+   +SE+  ++ E    S  ++  + RL     +H+ E      A
Sbjct: 964  AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 1019

Query: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
             EG ++  ++ +   +++   +E+++  L  +   LS+E   L+    E    +     E
Sbjct: 1020 EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1076

Query: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
              ++ S N +   ++  I+++E + +  E +  ++ EK+K +L+  S++L     E+  Q
Sbjct: 1077 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1133

Query: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
            ++A E + ++  KE        +E+Q A    + +    +++  + R+  + L     DL
Sbjct: 1134 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185

Query: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371
            E E   + +  K+ +D  + L    G+  D   S+  ++    L+ KRE E
Sbjct: 1186 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1233


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  548 bits (1412), Expect = e-155
 Identities = 326/975 (33%), Positives = 542/975 (55%), Gaps = 86/975 (8%)

Query: 68   GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYS 126
            G +D+ +L+ LH  ++++NL  R+  ++ IYTY G IL ++NPY+ +  +Y  A +  YS
Sbjct: 64   GVDDMASLTELHGGSIMYNLFQRYKRNQ-IYTYIGSILASVNPYQPIAGLYEPATMEQYS 122

Query: 127  GQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGS 186
             +++G++ PHIFA+A E Y+ + + + NQ I++SGESGAGKT S +  +++ + +S+   
Sbjct: 123  RRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSL 182

Query: 187  NAHVEDK-------VLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMST 239
               +++K       +L S+PI EA GNAKT  N+NSSRFGK+ +++  ++  I G  +  
Sbjct: 183  ELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVD 242

Query: 240  YLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVND 299
            YLLEK+RVV Q+  ERNYHIFY L A  +  E +   L + E ++Y    G    + ++D
Sbjct: 243  YLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISD 302

Query: 300  RAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFC 359
            +    E      ++ F ++   +V ++LA ILHLGN++    G  + S     + L    
Sbjct: 303  QESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFK---TALGRSA 359

Query: 360  ELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQ 419
            ELLGL+  ++   L  R +    E ++ P+   QAV++RD+LA  +YA  F++++++IN 
Sbjct: 360  ELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINS 419

Query: 420  ALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKED 479
             ++   +    IG+LDI+GFE F+VN FEQF INYANEKLQ+ FN H+F LEQ EY +E 
Sbjct: 420  RIK-GNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREG 478

Query: 480  IPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
            + W  ID+ DN   +DLIE K+G+L L++EE   P  TD   L+KL++   N N  + KP
Sbjct: 479  LVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHAN-NHFYVKP 537

Query: 540  RMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSP 599
            R++  +F ++H+A +V+Y   G LEKNRDT  D L+ +LR S+F    + F+        
Sbjct: 538  RVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEH------- 590

Query: 600  FGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPF 659
                ++ ++ +  +K  SKH R TV S+F+ SL+ LM TL+++ P +VRCIKPN +K+P 
Sbjct: 591  ----VSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646

Query: 660  EFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKV 719
            +FD   ++ QLR  G+LET+RI    Y  R  + +FY RY +LM    L   D +  C  
Sbjct: 647  QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALP-EDVRGKCTS 705

Query: 720  VLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRE 779
            +L      ++++Q GKTK+F R      LEK R +++  + ++++ H+ G+L RK++   
Sbjct: 706  LLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY--- 762

Query: 780  RRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQA 839
                             RK +        +  +IIQK+ R +L+R  +  ++ A I  Q 
Sbjct: 763  -----------------RKVL--------YCVVIIQKNYRAFLLRRRFLHLKKAAIVFQK 797

Query: 840  YSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLE 899
              RG +ARR YR++                LA +R Q  ++         + +  +KK  
Sbjct: 798  QLRGQIARRVYRQL----------------LAEKREQEEKK---------KQEEEEKKKR 832

Query: 900  DQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLA 959
            ++ +       +   L A +  +  K Q+LEA L+K+        E  K+  +   E++ 
Sbjct: 833  EEEERERERERREAELRAQQEEETRKQQELEA-LQKSQKEAELTRELEKQKENKQVEEIL 891

Query: 960  KLQKHNSELETQKEQIQLKLQEKT-EELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELK 1018
            +L+K   +L+  KEQ +L L E + ++L+E+ D   ++L     +EE  R   E    L 
Sbjct: 892  RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRL-----EEEACRAAQEFLESLN 946

Query: 1019 TQDYEKQIQSLKEEI 1033
              + ++ +++++  +
Sbjct: 947  FDEIDECVRNIERSL 961



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 84/384 (21%), Positives = 160/384 (41%), Gaps = 97/384 (25%)

Query: 744  QVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAV 803
            Q+ Y   L   ++R++   V++  + + +R K L      L + +  RG+ T    +   
Sbjct: 656  QLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRN---LALPEDVRGKCTSLLQLYDA 712

Query: 804  ALKEAW----AAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKA 859
            +  E W      + +++     L +   + +  A + ++A+  GFLAR++YRK+L  +  
Sbjct: 713  SNSE-WQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL--YCV 769

Query: 860  VILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALR 919
            VI+QK  RA+L RRRF  +++  +  Q   R Q  ++                       
Sbjct: 770  VIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVY--------------------- 808

Query: 920  AGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKE----QI 975
                   ++L AE       +R  EEK K+     EEK     K   E E ++E    + 
Sbjct: 809  -------RQLLAE-------KREQEEKKKQEE---EEK-----KKREEEERERERERREA 846

Query: 976  QLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKA 1035
            +L+ Q++ E  K+       Q  + +QK +++    E + EL+ Q   KQ+    EEI  
Sbjct: 847  ELRAQQEEETRKQ-------QELEALQKSQKE---AELTRELEKQKENKQV----EEILR 892

Query: 1036 LKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
            L+ E   LQ + E                          ++E+ L +A    +++    +
Sbjct: 893  LEKEIEDLQRMKE--------------------------QQELSLTEASLQKLQERRDQE 926

Query: 1096 KREMREKMSEITKQLLESYDIEDV 1119
             R + E+     ++ LES + +++
Sbjct: 927  LRRLEEEACRAAQEFLESLNFDEI 950



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 68/290 (23%), Positives = 117/290 (40%), Gaps = 75/290 (25%)

Query: 845  LARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKE 904
            L +RR  ++   H A++++ +   +LAR++++ +   V+ IQ  YR   L+++     K 
Sbjct: 734  LEKRREEEV--SHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKA 791

Query: 905  NHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKH 964
                 ++L    A R                              YR  + EK       
Sbjct: 792  AIVFQKQLRGQIARRV-----------------------------YRQLLAEK------- 815

Query: 965  NSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEK 1024
                   +EQ + K QE+ E+ K              ++EER+R    +  EL+ Q  E+
Sbjct: 816  -------REQEEKKKQEEEEKKKR-------------EEEERERERERREAELRAQQEEE 855

Query: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084
              +  ++E++AL+  + + +   E           E  + +KQV+ I   EKEIE LQ  
Sbjct: 856  TRK--QQELEALQKSQKEAELTRE----------LEKQKENKQVEEILRLEKEIEDLQRM 903

Query: 1085 KIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNED 1134
            K   E+   S      +K+ E   Q L    +E+   R + E LE LN D
Sbjct: 904  K---EQQELSLTEASLQKLQERRDQELRR--LEEEACRAAQEFLESLNFD 948



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 44/207 (21%), Positives = 96/207 (46%), Gaps = 24/207 (11%)

Query: 1142 EGLKKATRVLESHF-------QSQKDCYEKEIEALNFKVVHLSQEINHLQK---LFREEN 1191
            E +  A  V+ +H        Q +K  Y   I   N++   L +   HL+K   +F+++ 
Sbjct: 740  EEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQ- 798

Query: 1192 DINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLH 1251
                 +R ++ R     ++    +Q+    EK+KQ+ E +   + E+ + + E    +L 
Sbjct: 799  -----LRGQIARRVYRQLLAEKREQE----EKKKQEEEEKKKREEEERERERERREAELR 849

Query: 1252 RSQEEE-GTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
              QEEE   Q++    Q      E  + ++K +E ++  + L+ + E E   +   +QE 
Sbjct: 850  AQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE- 908

Query: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQ 1337
              L+L    L++  + +D+ +++L+++
Sbjct: 909  --LSLTEASLQKLQERRDQELRRLEEE 933


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score =  546 bits (1407), Expect = e-155
 Identities = 436/1414 (30%), Positives = 688/1414 (48%), Gaps = 133/1414 (9%)

Query: 7    YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65
            +T    VW+P     +++A +  +   G++   + L E G  L     P       NP  
Sbjct: 50   WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103

Query: 66   LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125
                 D+  L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYKQLPIY +AI+  Y
Sbjct: 104  FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162

Query: 126  SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185
             G+   ++ PH++AV E AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S 
Sbjct: 163  RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222

Query: 186  ---------------SNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQN 230
                           S   +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD   
Sbjct: 223  KGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAG 282

Query: 231  QIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGG 290
             I+GAN+ TYLLEKSR + Q+++E ++HIFYQL   A +     L L     + +   G 
Sbjct: 283  YIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGP 342

Query: 291  NTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE 350
            ++      +R    ET ++  +LGF  +  + + ++++A+L  GN+ +    N   +   
Sbjct: 343  SS--SPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMP 400

Query: 351  DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLF 410
            D++  +  C LLGL     ++ L   +I    + V K  T+ QA  A +ALAK  Y  LF
Sbjct: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLF 460

Query: 411  DFIVERINQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFK 469
             ++V R+N+AL  S +Q  +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN  +F 
Sbjct: 461  RWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFV 520

Query: 470  LEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKL 525
            LEQEEY +E IPWT +DF  D QP IDLIE      G+L LLDEEC  P  TD+++++K+
Sbjct: 521  LEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKV 580

Query: 526  YNNFVNRNPLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKF 583
                   +P F++PR       F + H+A KV+YK   +L KN D + D +  +L  S  
Sbjct: 581  AQE-QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639

Query: 584  HLCANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATT 643
             L A  +++          + ++       +P    FR TVG  ++ SL  LM TL+ T 
Sbjct: 640  RLTAEIWKDVEGIVG-LEQVSSLGDGPPGGRPRRGMFR-TVGQLYKESLSRLMATLSNTN 697

Query: 644  PHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILM 703
            P +VRCI PN EK   + + + ++ QLR  GVLE IRI  Q +P+R  + EF  RY IL 
Sbjct: 698  PSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILT 757

Query: 704  TKQ-ELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVM 762
                   F D K+ C+ ++  L  D N Y+ G++KIFFRAG +A LE+ R  K+    V 
Sbjct: 758  PNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVS 817

Query: 763  VQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYL 822
             Q   RG+L R+ F + ++           QQ+              A  ++Q++C  YL
Sbjct: 818  FQAAARGYLARRAFQKRQQ-----------QQS--------------ALRVMQRNCAAYL 852

Query: 823  VRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFV 882
                +Q  R+ T       +  L   R  ++L+  +A  LQK                  
Sbjct: 853  KLRHWQWWRLFTKV-----KPLLQVTRQDEVLQA-RAQELQKVQE--------------- 891

Query: 883  LNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVE-----KIQKLEAELEKAA 937
            L  Q    V  LQ ++    +E   L E+L + A L A   E       +K E EL  + 
Sbjct: 892  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 951

Query: 938  THRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKE-----QIQLKLQEKTEELK-EKMD 991
               R  EE+    +   E+K  +LQ+H  ELE   E     + +L+L++ T E K +K +
Sbjct: 952  LEARVGEEEECSRQMQTEKK--RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFE 1009

Query: 992  NLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEH 1051
                 L D   K  ++R LLE     +  ++  Q    +E++K+L   +++ +  +    
Sbjct: 1010 EDLLLLEDQNSKLSKERKLLED----RLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD-- 1063

Query: 1052 VTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLL 1111
               D L+ E     +  K     + E   LQ Q ++ ++  +  + ++  K  E+   L 
Sbjct: 1064 -MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122

Query: 1112 ESYDIEDVRSRLSVEDLEHLNE-DGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALN 1170
             + D    R++L    L+ L E    L  A E L ++ RV  +  + Q+    +E+EAL 
Sbjct: 1123 RAEDEGGARAQL----LKSLREAQAALAEAQEDL-ESERVARTKAEKQRRDLGEELEALR 1177

Query: 1171 FKVVHL--------------SQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQ 1216
             ++                  QE+  L+K   EE  I+E+   E+ +       + +  +
Sbjct: 1178 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ--RHGQALGELAE 1235

Query: 1217 QISELEKQKQDLE-IRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIH---- 1271
            Q+ +  + K   E  RL  +AE  + + E  S Q  R + E+  +R  L+ Q E+     
Sbjct: 1236 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ-EVQGRAG 1294

Query: 1272 --TKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329
               + + +  +K+Q  Q   +++               +E S    +  D +E L  + R
Sbjct: 1295 DGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETR 1354

Query: 1330 VIKKLQDQVKTL-SKTIGKANDVHSSSGPKEYLG 1362
                L  +V+ + ++  G    +   +  +E  G
Sbjct: 1355 AKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1388



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%)

Query: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903
            +R++ ++L E KA +L+        R   +   R    + LT  +   Q  +++LE QN+
Sbjct: 1475 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1532

Query: 904  ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
                 +E L S        V ++++     E+AA   R    + +    A E+   +L+ 
Sbjct: 1533 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1592

Query: 964  HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020
                L+TQ E+    LQ + E  +E+   L KQL D +V+++E  +QR L   +      
Sbjct: 1593 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1643

Query: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
               K+++   EE+KA      Q             G +  V +L K    + E  +E+E 
Sbjct: 1644 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1688

Query: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137
             +  +    + + SQ RE  +++  +  ++L   E     D   R + +D + + ++   
Sbjct: 1689 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1741

Query: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
              A   L KA  +LE            E   L  ++  L +E+   Q      ND    +
Sbjct: 1742 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1787

Query: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249
              +V  LT+E      F  +      +LE+Q Q+L  RL E+      + K  +  L ++
Sbjct: 1788 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1847

Query: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305
            L +++E+ E   R+ + +   +   EK  ++++ +++E +  +D L+ Q E  +  VK  
Sbjct: 1848 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1907

Query: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
             RQ      EASR     R L+ EL+      + +  +V TL
Sbjct: 1908 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1949



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%)

Query: 876  QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933
            Q  R   L  QL  + + LQ  L     E     + L SL   +A   E  + LE+E   
Sbjct: 1099 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1158

Query: 934  -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983
              KA   RR+  E+ +  R  +E+ L      Q+  S+ E +  +++  L+E+T      
Sbjct: 1159 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1218

Query: 984  -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039
             +EL+++      +L + +++  R +   EK+    E +  +   ++ SL+   +  +  
Sbjct: 1219 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1278

Query: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081
            + +L+  L E +    DG +A      K  +  +E E                 KE+   
Sbjct: 1279 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338

Query: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141
            +AQ  D ++ +Q    E R K++  ++      +   +R +L  E         EL  A 
Sbjct: 1339 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1395

Query: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190
              L +  R        LE+  ++++    +E EAL  ++   ++ ++ L++    L +E 
Sbjct: 1396 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1454

Query: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250
            +D    +  +   +++       F Q ++E EK      +   E+AE    + E  +  L
Sbjct: 1455 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1513

Query: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
             R+ EEE   R+ LE QN     E E L+    ++ ++   L++             Q A
Sbjct: 1514 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1566

Query: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
            + L  +  +LE+EL   +    +L+  V+ L
Sbjct: 1567 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1597



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%)

Query: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084
            Q+    E ++A   E  ++Q L +        L+  VA+L ++   ++E  +    L A+
Sbjct: 871  QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 930

Query: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
              +    + ++K+E+   +SE+  ++ E    S  ++  + RL     +H+ E      A
Sbjct: 931  AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 986

Query: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
             EG ++  ++ +   +++   +E+++  L  +   LS+E   L+    E    +     E
Sbjct: 987  EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1043

Query: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
              ++ S N +   ++  I+++E + +  E +  ++ EK+K +L+  S++L     E+  Q
Sbjct: 1044 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1100

Query: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
            ++A E + ++  KE        +E+Q A    + +    +++  + R+  + L     DL
Sbjct: 1101 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1152

Query: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371
            E E   + +  K+ +D  + L    G+  D   S+  ++    L+ KRE E
Sbjct: 1153 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1200


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  500 bits (1288), Expect = e-141
 Identities = 306/800 (38%), Positives = 447/800 (55%), Gaps = 49/800 (6%)

Query: 68   GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127
            G  D+T L  L E  VL NL+IRF E  LIYTY G ILV++NPY+   IYG   +  Y+G
Sbjct: 1223 GVEDMTQLEDLQETTVLSNLKIRF-ERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281

Query: 128  QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187
            + +G+  PH+FAVA  A+ +M    +NQ II+SGESG+GKT + +  +RY A +++    
Sbjct: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQK-RE 1340

Query: 188  AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRV 247
               + K+L + P+ E+ GNAKT RNDNSSRFGK+ EI F E   I GA  S YLLEKSR+
Sbjct: 1341 VMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399

Query: 248  VFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQ 307
            VFQ++NERNYHIFY+L A       +   L  AE + Y   GGN  I G +D  +     
Sbjct: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459

Query: 308  KTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDS--HLKVFCELLGLE 365
                +LGF  + Q  +F+ILA+ILHLGNV       +   V+   S   ++   ELL + 
Sbjct: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQIS 1519

Query: 366  SGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQFSG 425
               + + +  +   T  E +  P+T   AV+ARDA+AK +YA LF +++ R+N  +  S 
Sbjct: 1520 PEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV--SP 1577

Query: 426  KQHTF-IGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTL 484
            +Q T  I +LDIYGFE    NSFEQ CINYANE LQ  FN  VF+ EQEEY++E I W  
Sbjct: 1578 RQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQE 1637

Query: 485  IDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSN 543
            I F DNQP I+LI  K  GIL +LD++C  P  TD  +LQK + +    NPL+ KP+M  
Sbjct: 1638 ITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHH-GANPLYSKPKMPL 1696

Query: 544  TSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPFGSM 603
              F I+H+A KV Y+   FL+KN D V   ++++   S+  + A+ F  +    +P    
Sbjct: 1697 PEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQ--- 1753

Query: 604  ITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDS 663
              +  +  V +    H   TV +KF+ SL  L+E +    P ++RC+KPN +K P  F+ 
Sbjct: 1754 -RLGKSSSVTRLYKAH---TVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEP 1809

Query: 664  KRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMT-KQELSFSDKKEVCKVVLH 722
              ++ QLR  GVLET+RI  + +P R  +  F  RY  L+  K +L  +   ++C  VL 
Sbjct: 1810 DVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANG--DMCVSVLS 1867

Query: 723  RLIQDS-NQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERR 781
            RL +   N Y+ G +K+F +      LE +R   L  + + +Q+ +RG+  +++F     
Sbjct: 1868 RLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRF----- 1922

Query: 782  AALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYS 841
                        +++R  I           I++Q   RGYL R  YQ +R + +  ++  
Sbjct: 1923 ------------RSLRHKI-----------ILLQSRARGYLARQRYQQMRRSLVKFRSLV 1959

Query: 842  RGFLARRRYRKMLEEHKAVI 861
              +++RRRY K+  E +  +
Sbjct: 1960 HAYVSRRRYLKLRAEWRCQV 1979



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 27/74 (36%), Positives = 44/74 (59%), Gaps = 10/74 (13%)

Query: 821  YLVRSLYQLIR--------MATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLAR 872
            +L   LYQL+         +A +T+Q   RGF  +RR+R +   HK ++LQ  AR +LAR
Sbjct: 1885 FLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSL--RHKIILLQSRARGYLAR 1942

Query: 873  RRFQSIRRFVLNIQ 886
            +R+Q +RR ++  +
Sbjct: 1943 QRYQQMRRSLVKFR 1956


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,262,889
Number of Sequences: 37866
Number of extensions: 2601382
Number of successful extensions: 28765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 421
Number of HSP's successfully gapped in prelim test: 1284
Number of HSP's that attempted gapping in prelim test: 11416
Number of HSP's gapped (non-prelim): 7745
length of query: 1742
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1626
effective length of database: 13,855,062
effective search space: 22528330812
effective search space used: 22528330812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.