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Search of human proteins with 151108411
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo
sapiens]
(612 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens] 1240 0.0
gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens] 1240 0.0
gi|151108435 BTB (POZ) domain containing 9 isoform b [Homo sapiens] 1103 0.0
gi|225543407 BTB domain protein BDPL [Homo sapiens] 103 4e-22
gi|59814146 BTB (POZ) domain containing 1 isoform 2 [Homo sapiens] 101 2e-21
gi|13376848 BTB (POZ) domain containing 1 isoform 1 [Homo sapiens] 101 2e-21
gi|7662402 BTB/POZ domain containing protein 3 isoform a [Homo s... 101 2e-21
gi|31317209 BTB/POZ domain containing protein 3 isoform b [Homo ... 101 2e-21
gi|211904190 hypothetical protein LOC149478 [Homo sapiens] 99 9e-21
gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens] 99 1e-20
gi|40807500 kelch-like 20 [Homo sapiens] 98 2e-20
gi|166235129 kelch-like 3 [Homo sapiens] 91 2e-18
gi|109150407 kelch-like 6 [Homo sapiens] 90 7e-18
gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] 87 6e-17
gi|11056006 kelch-like 12 [Homo sapiens] 86 1e-16
gi|40018614 DRE1 protein [Homo sapiens] 86 1e-16
gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens] 84 4e-16
gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens] 84 4e-16
gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo... 80 4e-15
gi|38194229 kelch-like 17 [Homo sapiens] 80 4e-15
gi|8922854 kelch-like 26 [Homo sapiens] 80 5e-15
gi|5174473 intracisternal A particle-promoted polypeptide isofor... 79 9e-15
gi|223890235 intracisternal A particle-promoted polypeptide isof... 79 9e-15
gi|48717263 speckle-type POZ protein-like [Homo sapiens] 78 2e-14
gi|55925608 kelch-like 21 [Homo sapiens] 78 2e-14
gi|227497736 T-cell activation kelch repeat protein [Homo sapiens] 78 3e-14
gi|56117834 speckle-type POZ protein [Homo sapiens] 78 3e-14
gi|56117832 speckle-type POZ protein [Homo sapiens] 78 3e-14
gi|56117830 speckle-type POZ protein [Homo sapiens] 78 3e-14
gi|56117828 speckle-type POZ protein [Homo sapiens] 78 3e-14
>gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
Length = 612
Score = 1240 bits (3209), Expect = 0.0
Identities = 612/612 (100%), Positives = 612/612 (100%)
Query: 1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY 60
MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
Sbjct: 1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY 60
Query: 61 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY 120
FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
Sbjct: 61 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY 120
Query: 121 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS 180
GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
Sbjct: 121 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS 180
Query: 181 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR 240
LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
Sbjct: 181 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR 240
Query: 241 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT 300
PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
Sbjct: 241 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT 300
Query: 301 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW 360
QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
Sbjct: 301 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW 360
Query: 361 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL 420
VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
Sbjct: 361 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL 420
Query: 421 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM 480
IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
Sbjct: 421 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM 480
Query: 481 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG 540
IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
Sbjct: 481 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG 540
Query: 541 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP 600
THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
Sbjct: 541 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP 600
Query: 601 GSNSRSPNRQHQ 612
GSNSRSPNRQHQ
Sbjct: 601 GSNSRSPNRQHQ 612
>gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
Length = 612
Score = 1240 bits (3209), Expect = 0.0
Identities = 612/612 (100%), Positives = 612/612 (100%)
Query: 1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY 60
MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
Sbjct: 1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY 60
Query: 61 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY 120
FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
Sbjct: 61 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY 120
Query: 121 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS 180
GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
Sbjct: 121 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS 180
Query: 181 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR 240
LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
Sbjct: 181 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR 240
Query: 241 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT 300
PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
Sbjct: 241 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT 300
Query: 301 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW 360
QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
Sbjct: 301 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW 360
Query: 361 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL 420
VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
Sbjct: 361 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL 420
Query: 421 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM 480
IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
Sbjct: 421 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM 480
Query: 481 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG 540
IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
Sbjct: 481 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG 540
Query: 541 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP 600
THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
Sbjct: 541 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP 600
Query: 601 GSNSRSPNRQHQ 612
GSNSRSPNRQHQ
Sbjct: 601 GSNSRSPNRQHQ 612
>gi|151108435 BTB (POZ) domain containing 9 isoform b [Homo sapiens]
Length = 544
Score = 1103 bits (2852), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 69 MRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDS 128
MRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDS
Sbjct: 1 MRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDS 60
Query: 129 TSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLN 188
TSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLN
Sbjct: 61 TSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLN 120
Query: 189 IVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPD 248
IVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPD
Sbjct: 121 IVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPD 180
Query: 249 AILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHG 308
AILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHG
Sbjct: 181 AILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHG 240
Query: 309 FSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQ 368
FSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQ
Sbjct: 241 FSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQ 300
Query: 369 YLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVA 428
YLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVA
Sbjct: 301 YLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVA 360
Query: 429 TIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLL 488
TIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLL
Sbjct: 361 TIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLL 420
Query: 489 WDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEV 548
WDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEV
Sbjct: 421 WDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEV 480
Query: 549 FHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGSNSRSPN 608
FHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGSNSRSPN
Sbjct: 481 FHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGSNSRSPN 540
Query: 609 RQHQ 612
RQHQ
Sbjct: 541 RQHQ 544
>gi|225543407 BTB domain protein BDPL [Homo sapiens]
Length = 485
Score = 103 bits (258), Expect = 4e-22
Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 21/241 (8%)
Query: 22 LSEHIGALLIGEEYGDVTFVV----EKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE 77
L E + E DV FVV + PAH+ +LA F A+ YG + E + E
Sbjct: 69 LRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIH 128
Query: 78 IPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTIL 137
IP D AF +LLKY+Y+ L + + +L L A KY P L + +L T L
Sbjct: 129 IP--DVEPAAFLILLKYMYSDEIDL---EADTVLATLYAAKKYIVPALAKACVNFLETSL 183
Query: 138 NIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA 197
+N C+ + L+ P+LT C +D A+ L SEGF + + L IV R++
Sbjct: 184 EAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNT 243
Query: 198 PEKDIFLALLNW----CK--------HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLL 245
E +F A+LNW CK N + + VR+P M+L E N S +L
Sbjct: 244 KEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDIL 303
Query: 246 S 246
+
Sbjct: 304 T 304
>gi|59814146 BTB (POZ) domain containing 1 isoform 2 [Homo sapiens]
Length = 385
Score = 101 bits (252), Expect = 2e-21
Identities = 71/253 (28%), Positives = 114/253 (45%), Gaps = 27/253 (10%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEK----------KRFPAHRVILAARCQYFRALLYGGMRE 71
L E L E DV FV+ K +R PAHR +LAA F A+ GGM
Sbjct: 55 LKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMAT 114
Query: 72 SQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSE 131
+ E E+P D AF LL+++Y+ + E ++ L A KY P LE E
Sbjct: 115 TSAEIELP--DVEPAAFLALLRFLYSDEVQIGPE---TVMTTLYTAKKYAVPALEAHCVE 169
Query: 132 YLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVL 191
+L L N M A L+ P+L +C +D++ + +S+EGF + L ++
Sbjct: 170 FLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLE 229
Query: 192 RDSFAAPEKDIFLALLNWCK------------HNSKENHAEIMQAVRLPLMSLTELLNVV 239
RD+ + E +F A++ W + N ++ + + +R PLM++ E
Sbjct: 230 RDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGP 289
Query: 240 RPSGLLSPDAILD 252
SG+LS +++
Sbjct: 290 AQSGILSDREVVN 302
>gi|13376848 BTB (POZ) domain containing 1 isoform 1 [Homo sapiens]
Length = 482
Score = 101 bits (252), Expect = 2e-21
Identities = 71/253 (28%), Positives = 114/253 (45%), Gaps = 27/253 (10%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEK----------KRFPAHRVILAARCQYFRALLYGGMRE 71
L E L E DV FV+ K +R PAHR +LAA F A+ GGM
Sbjct: 55 LKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMAT 114
Query: 72 SQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSE 131
+ E E+P D AF LL+++Y+ + E ++ L A KY P LE E
Sbjct: 115 TSAEIELP--DVEPAAFLALLRFLYSDEVQIGPE---TVMTTLYTAKKYAVPALEAHCVE 169
Query: 132 YLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVL 191
+L L N M A L+ P+L +C +D++ + +S+EGF + L ++
Sbjct: 170 FLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLE 229
Query: 192 RDSFAAPEKDIFLALLNWCK------------HNSKENHAEIMQAVRLPLMSLTELLNVV 239
RD+ + E +F A++ W + N ++ + + +R PLM++ E
Sbjct: 230 RDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGP 289
Query: 240 RPSGLLSPDAILD 252
SG+LS +++
Sbjct: 290 AQSGILSDREVVN 302
>gi|7662402 BTB/POZ domain containing protein 3 isoform a [Homo
sapiens]
Length = 522
Score = 101 bits (251), Expect = 2e-21
Identities = 75/258 (29%), Positives = 118/258 (45%), Gaps = 25/258 (9%)
Query: 37 DVTFVVEK----KRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLL 92
DV FVV +R P H+ +LA F A+ YG + E + E IP D AF +L
Sbjct: 121 DVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIP--DVEPAAFLAML 178
Query: 93 KYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLY 152
KYIY L + +L L A KY P L + +L T L+ +N C+ + L+
Sbjct: 179 KYIYCDEIDLA---ADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLF 235
Query: 153 SLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCK- 211
P LT C +D A+ L SEGF + L +I+ R++ A E +F A LNW +
Sbjct: 236 EEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEV 295
Query: 212 -----------HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSES 260
N ++ + + +R+P M+L + N SG+L+ + D + +
Sbjct: 296 ECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAA 355
Query: 261 RDMDLNY----RGMLIPE 274
+ +L + R L+P+
Sbjct: 356 KKPELQFVSKARKGLVPQ 373
>gi|31317209 BTB/POZ domain containing protein 3 isoform b [Homo
sapiens]
Length = 461
Score = 101 bits (251), Expect = 2e-21
Identities = 75/258 (29%), Positives = 118/258 (45%), Gaps = 25/258 (9%)
Query: 37 DVTFVVEK----KRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLL 92
DV FVV +R P H+ +LA F A+ YG + E + E IP D AF +L
Sbjct: 60 DVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIP--DVEPAAFLAML 117
Query: 93 KYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLY 152
KYIY L + +L L A KY P L + +L T L+ +N C+ + L+
Sbjct: 118 KYIYCDEIDLA---ADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLF 174
Query: 153 SLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCK- 211
P LT C +D A+ L SEGF + L +I+ R++ A E +F A LNW +
Sbjct: 175 EEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEV 234
Query: 212 -----------HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSES 260
N ++ + + +R+P M+L + N SG+L+ + D + +
Sbjct: 235 ECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAA 294
Query: 261 RDMDLNY----RGMLIPE 274
+ +L + R L+P+
Sbjct: 295 KKPELQFVSKARKGLVPQ 312
>gi|211904190 hypothetical protein LOC149478 [Homo sapiens]
Length = 291
Score = 99.4 bits (246), Expect = 9e-21
Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 21/271 (7%)
Query: 23 SEHIGALLIGEEYGDVTFVV--EKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPL 80
S + +L+ Y DV FVV E++ AHR +LA RC +F+ LL P + + L
Sbjct: 16 SAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVP-SPVVL 74
Query: 81 QDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQ 140
EAF +L+++YT L +L+ L+ A +YG EL + +++ +L++
Sbjct: 75 STVPTEAFLAVLEFLYTNSVKLYRHS---VLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
Query: 141 NVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEK 200
VC VA + L +L C F++ ++QE L + GFL LS ALL ++ D E
Sbjct: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEA 191
Query: 201 DIFLALLNWCKHNS-------KENHAEIMQAVRLPLMSLTELLNVV---RPSGLLSPDAI 250
++ A +W + + E A +++ +RL L++ EL + R L+ + I
Sbjct: 192 ELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQI 251
Query: 251 LDAIKVRS-----ESRDMDLNYRGMLIPEEN 276
++A K + E+R R +P E+
Sbjct: 252 VEAWKCHALRRGDEARGAPCRRRRGTLPREH 282
>gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]
Length = 525
Score = 99.0 bits (245), Expect = 1e-20
Identities = 69/240 (28%), Positives = 109/240 (45%), Gaps = 21/240 (8%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEK----KRFPAHRVILAARCQYFRALLYGGMRESQPEAE 77
+ E L E DV F+V K +R PAHR +LA F A+ GGM + E E
Sbjct: 103 VQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIE 162
Query: 78 IPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTIL 137
+P D AF LLK++Y+ + E ++ L A KY P LE E+L L
Sbjct: 163 LP--DVEPAAFLALLKFLYSDEVQIGPE---TVMTTLYTAKKYAVPALEAHCVEFLKKNL 217
Query: 138 NIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA 197
N M A L+ P+L +C +D+N + +++EGF + L+ ++ RD+
Sbjct: 218 RADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGI 277
Query: 198 PEKDIFLALLNWCK------------HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLL 245
E +F A++ W + N ++ + + +R PLM++ E SG+L
Sbjct: 278 REVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGIL 337
>gi|40807500 kelch-like 20 [Homo sapiens]
Length = 609
Score = 98.2 bits (243), Expect = 2e-20
Identities = 79/280 (28%), Positives = 135/280 (48%), Gaps = 31/280 (11%)
Query: 1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY 60
+S+ HP + ++ +++L +H E DV VV K+ AHRVIL+A Y
Sbjct: 46 ISDKHPRQT------LEVINLLRKH-------RELCDVVLVVGAKKIYAHRVILSACSPY 92
Query: 61 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY 120
FRA+ G + ES+ + E+ ++D A +L+ + YT + T+ + + LL L
Sbjct: 93 FRAMFTGELAESR-QTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQ-- 149
Query: 121 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS 180
E++++ E+L L+ N A +S +L + F N QEV+ SE F+
Sbjct: 150 -LAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFML 208
Query: 181 LSKTALLNIVLRDSF-AAPEKDIFLALLNWCKHNSKENH---AEIMQAVRLPLMSLTELL 236
L L++I+ D E+ +F A++ W K++ +E +++Q VRLPL+S L+
Sbjct: 209 LPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLV 268
Query: 237 NVVRPSGLLSPDAILDAIKVRSESRDM-DLNYRGMLIPEE 275
V L+ D E RD+ D +L+P+E
Sbjct: 269 GTVGSDPLIKSD---------EECRDLVDEAKNYLLLPQE 299
>gi|166235129 kelch-like 3 [Homo sapiens]
Length = 587
Score = 91.3 bits (225), Expect = 2e-18
Identities = 75/301 (24%), Positives = 138/301 (45%), Gaps = 14/301 (4%)
Query: 37 DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96
DV V E AHRV+LAA YF A+ G M ES+ + +I ++D + + L+ YIY
Sbjct: 51 DVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAK-KIEIKDVDGQTLSKLIDYIY 109
Query: 97 TGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPK 156
T +T+E +VLL SL ++ + ++L + L+ N A +++
Sbjct: 110 TAEIEVTEENVQVLLPAASLLQ---LMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTD 166
Query: 157 LTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSF-AAPEKDIFLALLNWCKHNSK 215
L + +++ EV+ E FLSLS + +++ D + E+ +F A+++W + +
Sbjct: 167 LLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKE 226
Query: 216 ---ENHAEIMQAVRLPLMSLTELLNVVRPSGLLS-----PDAILDAIKVRSESRDMDLNY 267
E+ A++M+ VRLPL+ L+ V L+ D +++A+K D L
Sbjct: 227 TRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLI 286
Query: 268 RGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDD-DCRSGIEIKL 326
+ ++ VV G+ A+ + +++ D + CR+G+
Sbjct: 287 KNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMA 346
Query: 327 G 327
G
Sbjct: 347 G 347
>gi|109150407 kelch-like 6 [Homo sapiens]
Length = 621
Score = 89.7 bits (221), Expect = 7e-18
Identities = 63/229 (27%), Positives = 108/229 (47%), Gaps = 8/229 (3%)
Query: 21 ILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPL 80
IL + L + DV V+ + F HRV+LAA YFRA+ ++E E I +
Sbjct: 57 ILQNGLETLRMENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKY-EKRIII 115
Query: 81 QDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQ 140
+ AE LL Y YT +A +T + + +L+ A+ + F + D+ + +L LN +
Sbjct: 116 KGVDAETMHTLLDYTYTSKALITKQNVQRVLE---AANLFQFLRMVDACASFLTEALNPE 172
Query: 141 NVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDS-FAAPE 199
N +A +SL L ++ +N ++L+SE FL L L +I+ D + E
Sbjct: 173 NCVGILRLADTHSLDSLKKQVQSYIIQNFVQILNSEEFLDLPVDTLHHILKSDDLYVTEE 232
Query: 200 KDIFLALLNWCKHNSKENHA---EIMQAVRLPLMSLTELLNVVRPSGLL 245
+F +++W +H E +++ VRLPL+ + V L+
Sbjct: 233 AQVFETVMSWVRHKPSERLCLLPYVLENVRLPLLDPWYFVETVEADPLI 281
>gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens]
Length = 589
Score = 86.7 bits (213), Expect = 6e-17
Identities = 68/245 (27%), Positives = 112/245 (45%), Gaps = 13/245 (5%)
Query: 11 TAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMR 70
T + H + H+ L + DVT + FP HR +LAA +YF A+ G+R
Sbjct: 21 TLFHKASHPDCVLAHLNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLR 80
Query: 71 ESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTS 130
ES+ + + E +LL + Y+ R + +E E LL+ + F ++ D+ +
Sbjct: 81 ESRDDTVNFQDNLHPEVLELLLDFAYSSRIAINEENAESLLEAGDMLQ---FHDVRDAAA 137
Query: 131 EYLCTIL---NIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALL 187
E+L L N + + D L + + C+ + + V SE F SLSK LL
Sbjct: 138 EFLEKNLFPSNCLGMMLLSDAHQCRRLYEFSWRMCLV---HFETVRQSEDFNSLSKDTLL 194
Query: 188 NIVLRDSF-AAPEKDIFLALLNWCKHN---SKENHAEIMQAVRLPLMSLTELLNVVRPSG 243
+++ D E+ +F A+L W KH+ K + E++++VRL L+ L V
Sbjct: 195 DLISSDELETEDERVVFEAILQWVKHDLEPRKVHLPELLRSVRLALLPSDCLQEAVSSEA 254
Query: 244 LLSPD 248
LL D
Sbjct: 255 LLMAD 259
>gi|11056006 kelch-like 12 [Homo sapiens]
Length = 568
Score = 85.9 bits (211), Expect = 1e-16
Identities = 61/207 (29%), Positives = 104/207 (50%), Gaps = 8/207 (3%)
Query: 37 DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96
DVT VE+K FPAHR++LAA YF A+ + E + + + +Q TA +LL ++Y
Sbjct: 34 DVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSE-KGKPYVDIQGLTASTMEILLDFVY 92
Query: 97 TGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPK 156
T +T E + LL L G ++ + E+L + L+ N D A ++
Sbjct: 93 TETVHVTVENVQELLPAACLLQLKG---VKQACCEFLESQLDPSNCLGIRDFAETHNCVD 149
Query: 157 LTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA-PEKDIFLALLNWCKHNSK 215
L +F ++ EV+ E F+ LS+ + ++ D E+ +F A++NW KH K
Sbjct: 150 LMQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKK 209
Query: 216 ENH---AEIMQAVRLPLMSLTELLNVV 239
E ++Q VR+PL++ + +V+
Sbjct: 210 EREESLPNLLQYVRMPLLTPRYITDVI 236
>gi|40018614 DRE1 protein [Homo sapiens]
Length = 600
Score = 85.5 bits (210), Expect = 1e-16
Identities = 70/229 (30%), Positives = 105/229 (45%), Gaps = 29/229 (12%)
Query: 35 YGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKY 94
+ DV VE K FP HR +L+A YFRA+ RES+ E + + AEA L+Y
Sbjct: 65 FTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESR-EMLVEINGILAEAMECFLQY 123
Query: 95 IYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYL------CTILNIQNVCMTFDV 148
+YTG+ +T E + L + SL + L D+ +++L C L IQ
Sbjct: 124 VYTGKVKITTENVQYLFETSSL---FQISVLRDACAKFLEEQLDPCNCLGIQR------F 174
Query: 149 ASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFA-APEKDIFLALL 207
A +SL L C F + ++V E FL L K L++ + D E+ +F A++
Sbjct: 175 ADTHSLKTLFTKCKNFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVM 234
Query: 208 NWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKV 256
W + +AV L L ELL VR LL P+ + ++V
Sbjct: 235 RW-----------VYRAVDLRRPLLHELLTHVR-LPLLHPNYFVQTVEV 271
>gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens]
Length = 597
Score = 84.0 bits (206), Expect = 4e-16
Identities = 62/228 (27%), Positives = 112/228 (49%), Gaps = 13/228 (5%)
Query: 37 DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96
DVT V E AHRV+LAA YF A+ G M ES+ + + +++ ML+ Y+Y
Sbjct: 61 DVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAK-RVRIKEVDGWTLRMLIDYVY 119
Query: 97 TGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPK 156
T +T+E +VLL L +++ + E+L + L+ N A +++
Sbjct: 120 TAEIQVTEENVQVLLPAAGLLQ---LQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTD 176
Query: 157 LTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFA-APEKDIFLALLNWCKHNS- 214
L + +++ +V+ SE FL+L + +++ D + E+ +F A++ W H+
Sbjct: 177 LLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKD 236
Query: 215 --KENHAEIMQAVRLPLMSLTELLNVVRPSGLLS-----PDAILDAIK 255
+E A +M+ VRLPL+ L+ V L+ D +++A+K
Sbjct: 237 VRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMK 284
>gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens]
Length = 593
Score = 84.0 bits (206), Expect = 4e-16
Identities = 62/228 (27%), Positives = 112/228 (49%), Gaps = 13/228 (5%)
Query: 37 DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96
DVT V E AHRV+LAA YF A+ G M ES+ + + +++ ML+ Y+Y
Sbjct: 57 DVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAK-RVRIKEVDGWTLRMLIDYVY 115
Query: 97 TGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPK 156
T +T+E +VLL L +++ + E+L + L+ N A +++
Sbjct: 116 TAEIQVTEENVQVLLPAAGLLQ---LQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTD 172
Query: 157 LTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFA-APEKDIFLALLNWCKHNS- 214
L + +++ +V+ SE FL+L + +++ D + E+ +F A++ W H+
Sbjct: 173 LLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKD 232
Query: 215 --KENHAEIMQAVRLPLMSLTELLNVVRPSGLLS-----PDAILDAIK 255
+E A +M+ VRLPL+ L+ V L+ D +++A+K
Sbjct: 233 VRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMK 280
>gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo
sapiens]
Length = 589
Score = 80.5 bits (197), Expect = 4e-15
Identities = 61/246 (24%), Positives = 117/246 (47%), Gaps = 18/246 (7%)
Query: 25 HIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTT 84
H+ L + DV + FP HR +LAA +YF A+ GG++ESQ ++E+ ++
Sbjct: 35 HLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQ-DSEVNFDNSI 93
Query: 85 -AEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVC 143
E +LL Y Y+ R + +E E LL+ + F ++ D+ +E+L L+ N
Sbjct: 94 HPEVLELLLDYAYSSRVIINEENAESLLEAGDMLE---FQDIRDACAEFLEKNLHPTNCL 150
Query: 144 MTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSF-AAPEKDI 202
++ + KL + N Q + +E FL L + ++ ++ + E+ +
Sbjct: 151 GMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLV 210
Query: 203 FLALLNWCKHNSKENHA---EIMQAVRLPLM---------SLTELLNVVRPSGLLSPDAI 250
+ + +NW ++ K+ + E++Q VRL L+ ++ EL+ R S + +AI
Sbjct: 211 YESAINWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAI 270
Query: 251 LDAIKV 256
+K+
Sbjct: 271 RCKLKI 276
>gi|38194229 kelch-like 17 [Homo sapiens]
Length = 642
Score = 80.5 bits (197), Expect = 4e-15
Identities = 61/228 (26%), Positives = 110/228 (48%), Gaps = 13/228 (5%)
Query: 37 DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96
D+ V K AH+V+LA+ YF A+ M ES+ + + L D +A L+++ Y
Sbjct: 93 DIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESR-QTHVTLHDIDPQALDQLVQFAY 151
Query: 97 TGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPK 156
T + + + LL SL G + D+ ++L + L+ N A +S
Sbjct: 152 TAEIVVGEGNVQTLLPAASLLQLNG---VRDACCKFLLSQLDPSNCLGIRGFADAHSCSD 208
Query: 157 LTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAP-EKDIFLALLNWCKHN-- 213
L ++ ++ +V +E F+ L +L +V DS P E++++ A+L+W KH+
Sbjct: 209 LLKAAHRYVLQHFVDVAKTEEFMLLPLKQVLELVSSDSLNVPSEEEVYRAVLSWVKHDVD 268
Query: 214 -SKENHAEIMQAVRLPLMSLTELLNVVRPSGLL-----SPDAILDAIK 255
+++ +M+ VRLPL+S LL V L+ D +++A+K
Sbjct: 269 ARRQHVPRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIEALK 316
>gi|8922854 kelch-like 26 [Homo sapiens]
Length = 615
Score = 80.1 bits (196), Expect = 5e-15
Identities = 55/217 (25%), Positives = 104/217 (47%), Gaps = 7/217 (3%)
Query: 37 DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96
DV + ++ FPAH+V+LAA YFRA+ GGMRE+ + I L+ +A ++ + Y
Sbjct: 64 DVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDV-IELKGVSARGLRHIIDFAY 122
Query: 97 TGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPK 156
+ TL + + D L A + + E+L ++++ +A+ +SL
Sbjct: 123 SAEVTL---DLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLAS 179
Query: 157 LTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSF-AAPEKDIFLALLNWCKHN-- 213
L F R+ ++ E FL L L+ + + + E D+F A + W +H+
Sbjct: 180 LRESVDAFTFRHFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPA 239
Query: 214 SKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAI 250
+ + ++ +R PLM +EL++ V+ ++ D +
Sbjct: 240 RRPRASHVLCHIRFPLMQSSELVDSVQTLDIMVEDVL 276
>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
[Homo sapiens]
Length = 584
Score = 79.3 bits (194), Expect = 9e-15
Identities = 62/229 (27%), Positives = 109/229 (47%), Gaps = 14/229 (6%)
Query: 18 HVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE 77
H ++ I + G+ + DV V ++ F AHR++LAA YF AL GGM+ES +
Sbjct: 19 HAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDV- 77
Query: 78 IPLQDTTAEAFTMLLKYIYTGRATL-TDEKEEVLL--DFLSLAHKYGFPELEDSTSEYLC 134
+P+ A F +LL +IYTG + + +E+++ D L L E+ E+L
Sbjct: 78 VPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLT------EVVHLCCEFLK 131
Query: 135 TILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDS 194
++ N F + + L ++ + EV S E FL+L+K L+ I+ +
Sbjct: 132 GQIDPLNCIGIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEE 191
Query: 195 FA-APEKDIFLALLNWCKHN---SKENHAEIMQAVRLPLMSLTELLNVV 239
+ E +FLA + W + +++ E++ +R PL+ LL +
Sbjct: 192 LSIEDEYQVFLAAMQWILKDLGKRRKHVVEVLDPIRFPLLPPQRLLKYI 240
>gi|223890235 intracisternal A particle-promoted polypeptide isoform
2 [Homo sapiens]
Length = 582
Score = 79.3 bits (194), Expect = 9e-15
Identities = 62/229 (27%), Positives = 109/229 (47%), Gaps = 14/229 (6%)
Query: 18 HVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE 77
H ++ I + G+ + DV V ++ F AHR++LAA YF AL GGM+ES +
Sbjct: 19 HAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDV- 77
Query: 78 IPLQDTTAEAFTMLLKYIYTGRATL-TDEKEEVLL--DFLSLAHKYGFPELEDSTSEYLC 134
+P+ A F +LL +IYTG + + +E+++ D L L E+ E+L
Sbjct: 78 VPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLT------EVVHLCCEFLK 131
Query: 135 TILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDS 194
++ N F + + L ++ + EV S E FL+L+K L+ I+ +
Sbjct: 132 GQIDPLNCIGIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEE 191
Query: 195 FA-APEKDIFLALLNWCKHN---SKENHAEIMQAVRLPLMSLTELLNVV 239
+ E +FLA + W + +++ E++ +R PL+ LL +
Sbjct: 192 LSIEDEYQVFLAAMQWILKDLGKRRKHVVEVLDPIRFPLLPPQRLLKYI 240
>gi|48717263 speckle-type POZ protein-like [Homo sapiens]
Length = 392
Score = 78.2 bits (191), Expect = 2e-14
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 4/146 (2%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
L+E +G L + D +F V + F AH+ +LAAR F A+ M ES+ + + +
Sbjct: 186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESK-KNRVEIN 244
Query: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
D E F ++++IYTGRA D+ + + L+ A KY L+ E LC+ L+++N
Sbjct: 245 DLDPEVFKEMMRFIYTGRAPNLDKMAD---NLLAAADKYALERLKVMCEEALCSNLSVEN 301
Query: 142 VCMTFDVASLYSLPKLTCMCCMFMDR 167
V T +A L+S +L F++R
Sbjct: 302 VADTLVLADLHSAEQLKAQAIDFINR 327
>gi|55925608 kelch-like 21 [Homo sapiens]
Length = 597
Score = 78.2 bits (191), Expect = 2e-14
Identities = 70/245 (28%), Positives = 109/245 (44%), Gaps = 12/245 (4%)
Query: 9 PFTAVGEIDHVHILS--EHIGALLIGEEYGDVTFVVEKKR-FPAHRVILAARCQYFRALL 65
P + D H LS + L ++ DVT R FPAHR +LAA YFRA+
Sbjct: 6 PLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMF 65
Query: 66 YGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPEL 125
G +RES+ E + L + +LL + YTGR ++ + E LL L FP +
Sbjct: 66 AGQLRESRAE-RVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQ---FPAV 121
Query: 126 EDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTA 185
+++ +L L++ N D A +S L F+ R+ E L +E L
Sbjct: 122 KEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGE-LGAEQLERLPLAR 180
Query: 186 LLNIVLRDSFAAPEKDIFLAL-LNWCKHNSKENHA---EIMQAVRLPLMSLTELLNVVRP 241
LL + D P+++ L L W + + A ++++AVRLP + LL V
Sbjct: 181 LLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEA 240
Query: 242 SGLLS 246
L++
Sbjct: 241 EPLVA 245
>gi|227497736 T-cell activation kelch repeat protein [Homo sapiens]
Length = 601
Score = 77.8 bits (190), Expect = 3e-14
Identities = 52/194 (26%), Positives = 92/194 (47%), Gaps = 9/194 (4%)
Query: 45 KRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTD 104
K F HR +LAA YFR++ G+ ES + E+ + AE+ ++L Y YT R LT+
Sbjct: 59 KTFSCHRNVLAAISPYFRSMFTSGLTES-TQKEVRIVGVEAESMDLVLNYAYTSRVILTE 117
Query: 105 EKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMF 164
+ L S+ + P ++D ++Y+ + L+ QN F A Y +L +
Sbjct: 118 ANVQALFTAASI---FQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEY 174
Query: 165 MDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAP-EKDIFLALLNWCKHNSKENHAEI-- 221
+ + V + FL L+K L++I+ D E+ ++ +++ W +H E +
Sbjct: 175 IRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIIRWFEHEQNEREVHLPE 234
Query: 222 --MQAVRLPLMSLT 233
+ +R PLM T
Sbjct: 235 IFAKCIRFPLMEDT 248
>gi|56117834 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 77.8 bits (190), Expect = 3e-14
Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
L++ +G L + D V + F AH+ ILAAR F A+ M ES+ + +
Sbjct: 186 LADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKN-RVEIN 244
Query: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
D E F ++ +IYTG+A D+ + D L+ A KY L+ + LC+ L+++N
Sbjct: 245 DVEPEVFKEMMCFIYTGKAPNLDKMAD---DLLAAADKYALERLKVMCEDALCSNLSVEN 301
Query: 142 VCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSL 181
+A L+S +L F++ +A +VL + G+ S+
Sbjct: 302 AAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSM 341
>gi|56117832 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 77.8 bits (190), Expect = 3e-14
Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
L++ +G L + D V + F AH+ ILAAR F A+ M ES+ + +
Sbjct: 186 LADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKN-RVEIN 244
Query: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
D E F ++ +IYTG+A D+ + D L+ A KY L+ + LC+ L+++N
Sbjct: 245 DVEPEVFKEMMCFIYTGKAPNLDKMAD---DLLAAADKYALERLKVMCEDALCSNLSVEN 301
Query: 142 VCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSL 181
+A L+S +L F++ +A +VL + G+ S+
Sbjct: 302 AAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSM 341
>gi|56117830 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 77.8 bits (190), Expect = 3e-14
Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
L++ +G L + D V + F AH+ ILAAR F A+ M ES+ + +
Sbjct: 186 LADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKN-RVEIN 244
Query: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
D E F ++ +IYTG+A D+ + D L+ A KY L+ + LC+ L+++N
Sbjct: 245 DVEPEVFKEMMCFIYTGKAPNLDKMAD---DLLAAADKYALERLKVMCEDALCSNLSVEN 301
Query: 142 VCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSL 181
+A L+S +L F++ +A +VL + G+ S+
Sbjct: 302 AAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSM 341
>gi|56117828 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 77.8 bits (190), Expect = 3e-14
Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
L++ +G L + D V + F AH+ ILAAR F A+ M ES+ + +
Sbjct: 186 LADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKN-RVEIN 244
Query: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
D E F ++ +IYTG+A D+ + D L+ A KY L+ + LC+ L+++N
Sbjct: 245 DVEPEVFKEMMCFIYTGKAPNLDKMAD---DLLAAADKYALERLKVMCEDALCSNLSVEN 301
Query: 142 VCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSL 181
+A L+S +L F++ +A +VL + G+ S+
Sbjct: 302 AAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSM 341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,799,649
Number of Sequences: 37866
Number of extensions: 986602
Number of successful extensions: 3256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 2959
Number of HSP's gapped (non-prelim): 203
length of query: 612
length of database: 18,247,518
effective HSP length: 108
effective length of query: 504
effective length of database: 14,157,990
effective search space: 7135626960
effective search space used: 7135626960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.