Guide to the Human Genome
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Search of human proteins with 151101337

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151101337 coiled-coil domain containing 43 isoform 1 [Homo
sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151101337 coiled-coil domain containing 43 isoform 1 [Homo sa...   434   e-122
gi|151101335 coiled-coil domain containing 43 isoform 2 [Homo sa...   278   3e-75
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform...    48   8e-06
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ...    46   3e-05
gi|134152708 arginine and glutamate rich 1 [Homo sapiens]              46   3e-05
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    45   7e-05
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    45   7e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    45   7e-05
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    45   7e-05
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    45   7e-05
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    45   7e-05
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    45   7e-05
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    45   7e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    44   1e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    44   1e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    44   1e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    44   1e-04
gi|21264343 scaffold attachment factor B [Homo sapiens]                44   1e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]         44   1e-04
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    43   2e-04
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    43   2e-04
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      43   2e-04
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      43   2e-04
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      43   2e-04
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       43   2e-04
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso...    42   4e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    42   6e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    42   6e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    42   6e-04

>gi|151101337 coiled-coil domain containing 43 isoform 1 [Homo
           sapiens]
          Length = 224

 Score =  434 bits (1115), Expect = e-122
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDAL 60
           MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDAL
Sbjct: 1   MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDAL 60

Query: 61  QGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMV 120
           QGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMV
Sbjct: 61  QGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMV 120

Query: 121 SEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLE 180
           SEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLE
Sbjct: 121 SEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLE 180

Query: 181 RDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           RDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR
Sbjct: 181 RDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224


>gi|151101335 coiled-coil domain containing 43 isoform 2 [Homo
           sapiens]
          Length = 154

 Score =  278 bits (711), Expect = 3e-75
 Identities = 143/143 (100%), Positives = 143/143 (100%)

Query: 1   MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDAL 60
           MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDAL
Sbjct: 1   MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDAL 60

Query: 61  QGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMV 120
           QGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMV
Sbjct: 61  QGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMV 120

Query: 121 SEEEKQRKAALLAQYADVTDEED 143
           SEEEKQRKAALLAQYADVTDEED
Sbjct: 121 SEEEKQRKAALLAQYADVTDEED 143


>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
           [Homo sapiens]
          Length = 568

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 32/161 (19%)

Query: 69  EEDSLLNICKEIVERWSETQNVVTKV-KKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQR 127
           EE+     C++   RW E QN  T+  +K++E+  I TL++       + +   EEEK +
Sbjct: 232 EEEKEKAECRD-ERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290

Query: 128 KAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDE 187
           K A     A+   +E EA EK                 R   +E    A++ E + +R +
Sbjct: 291 KEAEKKAKAEAKRKEQEAKEKQ----------------RQAELEAARLAKEKEEEEVRQQ 334

Query: 188 S-QRKKEQD----KLQRERDKLA---------KQERKEKEK 214
           +   KKE+D     +++ER KL          +Q RKEKE+
Sbjct: 335 ALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEE 375



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/30 (50%), Positives = 21/30 (70%), Gaps = 2/30 (6%)

Query: 192 KEQDKLQRERDKLAKQE--RKEKEKKRTQR 219
           KE++K ++E +K AK E  RKE+E K  QR
Sbjct: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQR 313


>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
           [Homo sapiens]
          Length = 621

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 18/147 (12%)

Query: 69  EEDSLLNICKEIVERWSETQNVVTKV-KKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQR 127
           EE+     C++   RW E QN  T+  +K++E+  I TL++       + +   EEEK +
Sbjct: 232 EEEKEKAECRD-ERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290

Query: 128 KAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDE 187
           K A     A+   +E EA EK                 R   +E    A++ E + +R +
Sbjct: 291 KEAEKKAKAEAKRKEQEAKEKQ----------------RQAELEAARLAKEKEEEEVRQQ 334

Query: 188 SQRKKEQDKLQRERDKLAKQERKEKEK 214
           +   K++  +Q++  K  +Q+ +   K
Sbjct: 335 ALLAKKEKDIQKKAIKKERQKLRNSCK 361



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/30 (50%), Positives = 21/30 (70%), Gaps = 2/30 (6%)

Query: 192 KEQDKLQRERDKLAKQE--RKEKEKKRTQR 219
           KE++K ++E +K AK E  RKE+E K  QR
Sbjct: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQR 313



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 18/139 (12%)

Query: 49  QEEEEEEKLDALQGILSAFL-------EEDSLLNICKEIVERWSE-TQNVVTKVKKEDEV 100
           ++EEEE +  AL       +       E   L N CK     W+  + N   +VK  +EV
Sbjct: 325 EKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKT----WNHFSDNEAERVKMMEEV 380

Query: 101 QAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTD------EEDEADEKDDSGAT 154
           + +   +E  +   +   + S  ++  KAAL  Q  ++ +      EE EA  +  S  T
Sbjct: 381 EKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNT 440

Query: 155 TMNIGSDKLLFRNTNVEDV 173
             + G      +N + +D+
Sbjct: 441 EKSTGGGGNGSKNWSEDDL 459


>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
          Length = 273

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 43/171 (25%), Positives = 83/171 (48%), Gaps = 26/171 (15%)

Query: 49  QEEEEEEKLD-------ALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQ 101
           + EEEE+K +         Q I    +EE++   + + + +R  E        K++DE++
Sbjct: 100 KREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELE-----KRKDEIE 154

Query: 102 AIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSD 161
                  ++A+ +++ +++ E E+QR+A L AQ A   +EE+ A  ++           +
Sbjct: 155 REVLRRVEEAKRIMEKQLLEELERQRQAELAAQKA--REEEERAKREE----------LE 202

Query: 162 KLLFRNTNVEDVLNARKLERDSLRDESQRK--KEQDKLQRERDKLAKQERK 210
           ++L  N        A+  E      E QRK  +E+ KL++ER +  K+E+K
Sbjct: 203 RILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQK 253


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 125 KQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARK-LERDS 183
           K+R  AL  Q  +    E+E  ++              L  R   +E+    R+ LE   
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQ------------LLAERQKRIEEQKEQRRRLEEQQ 409

Query: 184 LRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
            R++  RK+++ + +R  ++  ++E + +  +  Q  +RK+
Sbjct: 410 RREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQ 450


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 125 KQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARK-LERDS 183
           K+R  AL  Q  +    E+E  ++              L  R   +E+    R+ LE   
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQ------------LLAERQKRIEEQKEQRRRLEEQQ 409

Query: 184 LRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
            R++  RK+++ + +R  ++  ++E + +  +  Q  +RK+
Sbjct: 410 RREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQ 450


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 125 KQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARK-LERDS 183
           K+R  AL  Q  +    E+E  ++              L  R   +E+    R+ LE   
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQ------------LLAERQKRIEEQKEQRRRLEEQQ 409

Query: 184 LRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
            R++  RK+++ + +R  ++  ++E + +  +  Q  +RK+
Sbjct: 410 RREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQ 450


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 125 KQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARK-LERDS 183
           K+R  AL  Q  +    E+E  ++              L  R   +E+    R+ LE   
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQ------------LLAERQKRIEEQKEQRRRLEEQQ 409

Query: 184 LRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
            R++  RK+++ + +R  ++  ++E + +  +  Q  +RK+
Sbjct: 410 RREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQ 450


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 14/131 (10%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDS------GATTMNIGS 160
           E+Q +I +K  +   ++K+  K     +Y+   +EE+E D  + S      G +T+    
Sbjct: 295 ERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDF 354

Query: 161 DKLLFRNTNVEDVLNARKLERDSLRDE-------SQRKKEQDKLQRERDKLAKQERKEKE 213
            +L   N    + L  ++LE+    +E       ++R+K  ++ + +R +L +Q+R+EKE
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 214 KKRTQRGERKR 224
            ++ Q  E++R
Sbjct: 415 LRKQQEREQRR 425


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 37/176 (21%), Positives = 88/176 (50%), Gaps = 11/176 (6%)

Query: 49  QEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIE 108
           ++EE+ ++ + ++       EE+  +   +E +++  E  N+  + +KE + Q +    E
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE--NMWEQEEKEWQQQRLP---E 437

Query: 109 KQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDE-ADEKDDSGATTMNIGSDKLLFRN 167
           ++ ++  + +M  +EEK     +  Q   + D+E+    EK       M    D++  + 
Sbjct: 438 QKEKLWEQEKMQEQEEK-----IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492

Query: 168 TNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERK 223
             + D       + + + ++ +R +E+++  RE+ K+ +QE K +E+K+TQ  E+K
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 30/151 (19%), Positives = 72/151 (47%), Gaps = 3/151 (1%)

Query: 76  ICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQY 135
           I K+  + W + + +  +  K  E +      EK+ +   K     E+E + +  L  Q 
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309

Query: 136 ADVTDEED---EADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKK 192
             + ++E+   E +EK       M    ++L  +   + +     + + + + ++ +R +
Sbjct: 310 EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 369

Query: 193 EQDKLQRERDKLAKQERKEKEKKRTQRGERK 223
           E+++  RE++K+ +QE K +E++R +  E+K
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKK 400



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 35/178 (19%), Positives = 85/178 (47%), Gaps = 13/178 (7%)

Query: 49  QEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIE 108
           QEE+   +   L+       E++  L   K++ E+  + Q    K+ +++E      + E
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE-----KMRE 328

Query: 109 KQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEED---EADEKDDSGATTMNIGSDKLLF 165
           ++ ++  +   + E+EKQ +     Q   + D+E+   E DE+       M    +K+  
Sbjct: 329 QEEKMWRQEERLWEQEKQMRE----QEQKMRDQEERMWEQDERLREKEERMR-EQEKMWE 383

Query: 166 RNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERK 223
           +   +++    R+ E+    +E   +++++K+Q++ + + +QE KE +++R    + K
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441



 Score = 35.0 bits (79), Expect = 0.052
 Identities = 22/107 (20%), Positives = 52/107 (48%), Gaps = 13/107 (12%)

Query: 118 RMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNAR 177
           R+  +EE+ R+   + Q  +   EE +  E++            K   +   + +    R
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEK-----------KTWDQEEKMREEERMR 563

Query: 178 KLERDSLRDESQRKKEQDKLQRERDKLAKQERK--EKEKKRTQRGER 222
           + E+    +E   +++++K+Q + +K+ +QE K  E+E+K  ++ E+
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 38/181 (20%), Positives = 81/181 (44%), Gaps = 20/181 (11%)

Query: 49  QEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIE 108
           QEE+  ++   +        E+D  L   +E  ER  E + +  + +K  E        E
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERL---REKEERMREQKKMWQQEEKMRE--------E 539

Query: 109 KQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEED---EADEKDDSGATTMNIGSDKLLF 165
           K+ Q   K     EE+ + +  +  +   + +EE+   E +EK       M    +K+  
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599

Query: 166 RNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERK--EKEKKRTQRGERK 223
           +    E+ +  ++ +     ++   ++E+DK+Q + + + +QE K  E+E+K  ++ E+ 
Sbjct: 600 Q----EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655

Query: 224 R 224
           R
Sbjct: 656 R 656



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 40/201 (19%), Positives = 92/201 (45%), Gaps = 32/201 (15%)

Query: 49  QEE---EEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIAT 105
           QEE   E+EEK+   +  +  + +E+ L    K++ E+  + ++   ++ ++DE      
Sbjct: 315 QEEKMWEQEEKMREQEEKM--WRQEERLWEQEKQMREQEQKMRDQEERMWEQDE-----R 367

Query: 106 LIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEA----DEKDDSGATTMNIGSD 161
           L EK+ ++  + +M  +EEK ++   + +      EE+E     +EK       M    +
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427

Query: 162 K------------LLFRNTNVEDVLNARKLERDSLRDES----QRKK--EQDKLQRERDK 203
           K             L+    +++       + + +RD+     Q KK   Q+K++ + D+
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487

Query: 204 LAKQERKEKEKKRTQRGERKR 224
           + +QE K +++++    + +R
Sbjct: 488 MWEQEEKMRDQEQKMWDQEER 508



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/89 (16%), Positives = 46/89 (51%), Gaps = 4/89 (4%)

Query: 140 DEEDEADEKDD---SGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQD- 195
           +EED+  E+++        M    +K+  +   + +     + + + ++ + ++ +EQ+ 
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681

Query: 196 KLQRERDKLAKQERKEKEKKRTQRGERKR 224
           K+Q + +K+ +QE K + ++    G+ ++
Sbjct: 682 KMQGQEEKMREQEEKMRGQEEKMWGQEEK 710


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 18/135 (13%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLL-- 164
           E+Q +I +K  +    +K+  K     +Y+   +EE+E  E++   ++ +N+  +  L  
Sbjct: 295 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR 354

Query: 165 -FRNTNVEDVLNARKLERDSLRDESQ--------------RKKEQDKLQRERDKLAKQER 209
            F     E+   +  L R  L  E Q              R+K  ++ + +R +L +Q+R
Sbjct: 355 DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414

Query: 210 KEKEKKRTQRGERKR 224
           +E+E +R Q  E++R
Sbjct: 415 REREARRQQEREQRR 429



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 32/169 (18%), Positives = 78/169 (46%), Gaps = 32/169 (18%)

Query: 51  EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQ 110
           EEEEE++   +G      E  S++N+  E     S  +    ++++E++ ++ A     +
Sbjct: 327 EEEEEEVPEQEG------EPSSIVNVPGE-----STLRRDFLRLQQENKERSEAL----R 371

Query: 111 AQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNV 170
            Q +++ + + E+E+ ++  L  +   +  ++++    ++                    
Sbjct: 372 RQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA------------ 419

Query: 171 EDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQR 219
                 R+ ER+  R E + K+  ++L+R R +  ++ R E+EK+R +R
Sbjct: 420 -----RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVER 463



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 120 VSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKL 179
           + +E K+R  AL  Q      +  E +E               L  R   +E     R+ 
Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYK----------RQLLAERQKRIEQQKEQRRR 408

Query: 180 ERDSLRDESQRKKEQDKLQRERDKLAKQE-------RKEKEKKRTQRGERKR 224
             +  R E + +++Q++ QR R++  K+        RKE+E++R    E++R
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRR 460


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 18/135 (13%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLL-- 164
           E+Q +I +K  +    +K+  K     +Y+   +EE+E  E++   ++ +N+  +  L  
Sbjct: 295 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR 354

Query: 165 -FRNTNVEDVLNARKLERDSLRDESQ--------------RKKEQDKLQRERDKLAKQER 209
            F     E+   +  L R  L  E Q              R+K  ++ + +R +L +Q+R
Sbjct: 355 DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414

Query: 210 KEKEKKRTQRGERKR 224
           +E+E +R Q  E++R
Sbjct: 415 REREARRQQEREQRR 429



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 32/169 (18%), Positives = 78/169 (46%), Gaps = 32/169 (18%)

Query: 51  EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQ 110
           EEEEE++   +G      E  S++N+  E     S  +    ++++E++ ++ A     +
Sbjct: 327 EEEEEEVPEQEG------EPSSIVNVPGE-----STLRRDFLRLQQENKERSEAL----R 371

Query: 111 AQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNV 170
            Q +++ + + E+E+ ++  L  +   +  ++++    ++                    
Sbjct: 372 RQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA------------ 419

Query: 171 EDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQR 219
                 R+ ER+  R E + K+  ++L+R R +  ++ R E+EK+R +R
Sbjct: 420 -----RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVER 463



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 120 VSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKL 179
           + +E K+R  AL  Q      +  E +E               L  R   +E     R+ 
Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYK----------RQLLAERQKRIEQQKEQRRR 408

Query: 180 ERDSLRDESQRKKEQDKLQRERDKLAKQE-------RKEKEKKRTQRGERKR 224
             +  R E + +++Q++ QR R++  K+        RKE+E++R    E++R
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRR 460


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 18/135 (13%)

Query: 108 EKQAQIVVKPRMVSEEEKQ-RKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLL-- 164
           E+Q +I +K  +    +K+  K     +Y+   +EE+E  E++   ++ +N+  +  L  
Sbjct: 295 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR 354

Query: 165 -FRNTNVEDVLNARKLERDSLRDESQ--------------RKKEQDKLQRERDKLAKQER 209
            F     E+   +  L R  L  E Q              R+K  ++ + +R +L +Q+R
Sbjct: 355 DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414

Query: 210 KEKEKKRTQRGERKR 224
           +E+E +R Q  E++R
Sbjct: 415 REREARRQQEREQRR 429



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 32/169 (18%), Positives = 78/169 (46%), Gaps = 32/169 (18%)

Query: 51  EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQ 110
           EEEEE++   +G      E  S++N+  E     S  +    ++++E++ ++ A     +
Sbjct: 327 EEEEEEVPEQEG------EPSSIVNVPGE-----STLRRDFLRLQQENKERSEAL----R 371

Query: 111 AQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNV 170
            Q +++ + + E+E+ ++  L  +   +  ++++    ++                    
Sbjct: 372 RQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA------------ 419

Query: 171 EDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQR 219
                 R+ ER+  R E + K+  ++L+R R +  ++ R E+EK+R +R
Sbjct: 420 -----RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVER 463



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 120 VSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKL 179
           + +E K+R  AL  Q      +  E +E               L  R   +E     R+ 
Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYK----------RQLLAERQKRIEQQKEQRRR 408

Query: 180 ERDSLRDESQRKKEQDKLQRERDKLAKQE-------RKEKEKKRTQRGERKR 224
             +  R E + +++Q++ QR R++  K+        RKE+E++R    E++R
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRR 460


>gi|21264343 scaffold attachment factor B [Homo sapiens]
          Length = 915

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 24/104 (23%), Positives = 55/104 (52%), Gaps = 6/104 (5%)

Query: 114 VVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVE-D 172
           V +PR   + E   +    ++       + E +E++      + I  ++L F+   +E +
Sbjct: 608 VKEPRKSRDSESHSRVRERSEREQRMQAQWEREERE-----RLEIARERLAFQRQRLERE 662

Query: 173 VLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKR 216
            +   +LER+ +  E +R++EQ+++ RER++L +Q+    E++R
Sbjct: 663 RMERERLERERMHVEHERRREQERIHREREELRRQQELRYEQER 706



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/51 (29%), Positives = 31/51 (60%), Gaps = 4/51 (7%)

Query: 178 KLERDSLRDESQR----KKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           ++ R+ L  + QR    + E+++L+RER  +  + R+E+E+   +R E +R
Sbjct: 646 EIARERLAFQRQRLERERMERERLERERMHVEHERRREQERIHREREELRR 696


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 2/104 (1%)

Query: 121 SEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLE 180
           SE +K+R+     +     + + E  +K+         G ++   R    +     R+ E
Sbjct: 34  SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93

Query: 181 RDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R   + E ++++ + + +RER K  K+ERKE+E++  QR ERKR
Sbjct: 94  RRKRKKEKKKRERKQRGRRERKK--KKERKERERENKQRRERKR 135



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 116 KPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLN 175
           + R   E EKQRK     +      E+ + + K             K   R         
Sbjct: 75  RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134

Query: 176 ARKLERDSLRDESQRKKEQDKLQRERDKLAKQER----------KEKEKKRTQRGERKR 224
            +K  +   R E +R+KE+ K +R+R K  K+ER          ++KE++R +R ERK+
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 17/74 (22%), Positives = 42/74 (56%)

Query: 151 SGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERK 210
           S    + + ++  +   +++      R+ ER   R E +++K + + +R+R++  K+++K
Sbjct: 6   SSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKK 65

Query: 211 EKEKKRTQRGERKR 224
            K+++R +  ERKR
Sbjct: 66  RKKRERGKERERKR 79



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 13/47 (27%), Positives = 35/47 (74%)

Query: 177 RKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERK 223
           +K ER+  R+ +++++++++ ++ER +  K+ +KE+ KK+ ++ +RK
Sbjct: 164 KKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210



 Score = 35.0 bits (79), Expect = 0.052
 Identities = 16/58 (27%), Positives = 38/58 (65%), Gaps = 1/58 (1%)

Query: 168 TNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQER-KEKEKKRTQRGERKR 224
           T  E      + ER+  + E ++++++++ ++E+ K  K+ER KE+E+KR +R ++++
Sbjct: 30  TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87



 Score = 35.0 bits (79), Expect = 0.052
 Identities = 13/40 (32%), Positives = 30/40 (75%)

Query: 185 RDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R   +RKKE+ + +RER++  +++ +E++++R ++ ERK+
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 15/43 (34%), Positives = 33/43 (76%), Gaps = 3/43 (6%)

Query: 185 RDESQRKKEQDKLQR--ERDKLAKQERKEKEKK-RTQRGERKR 224
           ++E ++K+E+++ +R  ER++  ++ERK++ KK R ++ ERK+
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 12/40 (30%), Positives = 30/40 (75%), Gaps = 2/40 (5%)

Query: 185 RDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R + +R+K++++ ++ER K  ++ERKE+ +++ +R + +R
Sbjct: 163 RKKEEREKKRERNRKERKK--ERERKERRERKKERKKERR 200


>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
          Length = 439

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 43/179 (24%), Positives = 78/179 (43%), Gaps = 18/179 (10%)

Query: 49  QEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKV---KKEDEVQAIAT 105
           +E+EE+   D     L   + ED        + ER +  + +V      + + EV+  A 
Sbjct: 74  EEQEEDSSSDPRLRRLQNRISED--------VEERLARHRKIVEPEVVGESDSEVEGDAW 125

Query: 106 LIEKQAQIVVKPRMVSEEEKQRKAALLAQYA-DVTDEEDEADEKDDSGATTMNIGSDKLL 164
            +E++     +   + +EE +R+  ++ Q A +  +EE E  E +D G +     S+   
Sbjct: 126 RMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEY 185

Query: 165 FRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERK 223
              T+ ED +  R      L+    RKK++  +Q    +  KQ+  E+E KR     RK
Sbjct: 186 EEYTDSEDEMEPR------LKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRK 238


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 1 [Homo
            sapiens]
          Length = 1834

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 35/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)

Query: 93   KVKKEDEVQAIATLIEKQAQIVVKP-RMVSEEEKQRKAALLAQYADVTDE-----EDEAD 146
            K++K+ ++  +  L ++  ++  KP R   E ++ RK  L  Q+     E     ED+ +
Sbjct: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581

Query: 147  EKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAK 206
            E+DD   T + +   +   R       ++   L +D  R   Q+ +E  K + E     +
Sbjct: 1582 EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE 1641

Query: 207  QERKEKEKKRTQR-GERKR 224
            +ER+ +E++RT+R  E KR
Sbjct: 1642 EERRRQEEERTKRDAEEKR 1660


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 2 [Homo
            sapiens]
          Length = 1651

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/138 (24%), Positives = 71/138 (51%), Gaps = 19/138 (13%)

Query: 93   KVKKEDEVQAIATLIEKQAQIVVKP-RMVSEEEKQRKAALLAQYADVTDEEDEADEKDDS 151
            K++K+ ++  +  L ++  ++  KP R   E ++ RK  L  Q+     E  + DE D+ 
Sbjct: 1523 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1582

Query: 152  GATTMNIGSDKLLFRNTNVEDVLNARKLERDS-LRDESQRKKEQ--DKLQRERDKLAKQE 208
                           + +V+ +L  ++LE +   RDE +R+++Q  +  +RE +  A+QE
Sbjct: 1583 E-------------EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE 1629

Query: 209  --RKEKEKKRTQRGERKR 224
              R+ +E++RT+R   ++
Sbjct: 1630 EERRRQEEERTKRDAEEK 1647


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 28/134 (20%), Positives = 67/134 (50%), Gaps = 17/134 (12%)

Query: 108 EKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRN 167
           E+Q +I +K  +    +K+ +          ++EED++  ++   ++ MN+  +  L R 
Sbjct: 295 ERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRRE 354

Query: 168 ---------TNVEDVLNARKLERDSLRDES--------QRKKEQDKLQRERDKLAKQERK 210
                    +N E +   ++L++   RD          QR++  ++ + ER ++ +Q+R+
Sbjct: 355 FLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRR 414

Query: 211 EKEKKRTQRGERKR 224
           E+E+++ Q  E++R
Sbjct: 415 EREQRKLQEKEQQR 428



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 13/48 (27%), Positives = 26/48 (54%)

Query: 177 RKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R++E    R+  QRK ++ + QR  + +    R+E+ ++  +  E KR
Sbjct: 406 RRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKR 453


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 28/134 (20%), Positives = 67/134 (50%), Gaps = 17/134 (12%)

Query: 108 EKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRN 167
           E+Q +I +K  +    +K+ +          ++EED++  ++   ++ MN+  +  L R 
Sbjct: 295 ERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRRE 354

Query: 168 ---------TNVEDVLNARKLERDSLRDES--------QRKKEQDKLQRERDKLAKQERK 210
                    +N E +   ++L++   RD          QR++  ++ + ER ++ +Q+R+
Sbjct: 355 FLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRR 414

Query: 211 EKEKKRTQRGERKR 224
           E+E+++ Q  E++R
Sbjct: 415 EREQRKLQEKEQQR 428



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 13/48 (27%), Positives = 26/48 (54%)

Query: 177 RKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R++E    R+  QRK ++ + QR  + +    R+E+ ++  +  E KR
Sbjct: 406 RRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKR 453


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 28/134 (20%), Positives = 67/134 (50%), Gaps = 17/134 (12%)

Query: 108 EKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRN 167
           E+Q +I +K  +    +K+ +          ++EED++  ++   ++ MN+  +  L R 
Sbjct: 295 ERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRRE 354

Query: 168 ---------TNVEDVLNARKLERDSLRDES--------QRKKEQDKLQRERDKLAKQERK 210
                    +N E +   ++L++   RD          QR++  ++ + ER ++ +Q+R+
Sbjct: 355 FLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRR 414

Query: 211 EKEKKRTQRGERKR 224
           E+E+++ Q  E++R
Sbjct: 415 EREQRKLQEKEQQR 428



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 13/48 (27%), Positives = 26/48 (54%)

Query: 177 RKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R++E    R+  QRK ++ + QR  + +    R+E+ ++  +  E KR
Sbjct: 406 RRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKR 453


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 28/134 (20%), Positives = 67/134 (50%), Gaps = 17/134 (12%)

Query: 108 EKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRN 167
           E+Q +I +K  +    +K+ +          ++EED++  ++   ++ MN+  +  L R 
Sbjct: 295 ERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRRE 354

Query: 168 ---------TNVEDVLNARKLERDSLRDES--------QRKKEQDKLQRERDKLAKQERK 210
                    +N E +   ++L++   RD          QR++  ++ + ER ++ +Q+R+
Sbjct: 355 FLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRR 414

Query: 211 EKEKKRTQRGERKR 224
           E+E+++ Q  E++R
Sbjct: 415 EREQRKLQEKEQQR 428



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 13/48 (27%), Positives = 26/48 (54%)

Query: 177 RKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR 224
           R++E    R+  QRK ++ + QR  + +    R+E+ ++  +  E KR
Sbjct: 406 RRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKR 453


>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
           isoform 1 [Homo sapiens]
          Length = 483

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 35/139 (25%), Positives = 71/139 (51%), Gaps = 12/139 (8%)

Query: 93  KVKKEDEVQAIATLIE--KQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDD 150
           K+K E +++    L++   Q  ++ KP    E+E  ++     + A   D+E+ +DE+  
Sbjct: 261 KLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKR-----EKAKKLDKENLSDERAS 315

Query: 151 SGATTMNIGSDKLLF----RNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAK 206
             + T+   SD  L     +    E   + R+ ER+  RD+ +  +E+++L+R+ ++  +
Sbjct: 316 GQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRR 375

Query: 207 Q-ERKEKEKKRTQRGERKR 224
           Q ER EKEK   ++ E  +
Sbjct: 376 QKERYEKEKTFKRKEEEMK 394



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 12/54 (22%), Positives = 32/54 (59%)

Query: 166 RNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQR 219
           + T +   L  ++  R+  R+E +R++ + K QRE ++   +E +++++K  ++
Sbjct: 196 KTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEK 249


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 26/137 (18%), Positives = 71/137 (51%), Gaps = 5/137 (3%)

Query: 93  KVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAA--LLAQYADVTDEEDEADEKDD 150
           K ++++E+      I +Q +I  +   + E+EK RK    +  Q   + D+E++  E+++
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516

Query: 151 S---GATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQ 207
                   +    +K+  +   + +     + + + + ++ ++ +EQ+K++R+ +K+ +Q
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576

Query: 208 ERKEKEKKRTQRGERKR 224
           E K +E+K   R + ++
Sbjct: 577 EEKIREQKEKIREQEEK 593



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 39/182 (21%), Positives = 86/182 (47%), Gaps = 11/182 (6%)

Query: 48  LQEEEEE--EKLDALQGILSAFLEEDSLLNICKEIVER--WSETQNVVTKVKKEDEVQAI 103
           LQ E +   ++L ++   L A +EE+ L N   +  E   W + + +    + E+++Q  
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ---EWEEKIQEQ 319

Query: 104 ATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKL 163
              I +Q +   K R   E+ ++++  +  +   +  +E+   EK++       +  +K 
Sbjct: 320 EEKIREQEE---KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376

Query: 164 LFRNTNVEDVLNARKL-ERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGER 222
                  E +    K+ E++  R E ++ +EQ+K Q +  K+ +QE K +E++   R + 
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436

Query: 223 KR 224
           K+
Sbjct: 437 KK 438



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 39/181 (21%), Positives = 93/181 (51%), Gaps = 18/181 (9%)

Query: 49  QEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKV--KKEDEVQAIATL 106
           QEE+  E+ + ++       E++  +   +E++    E    + ++  +KE++++ +   
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEK 385

Query: 107 IEKQAQIVVKPRMVSEEEKQRKAALLA-QYADVTDEEDEADEKDDSGATTMNIGSDKLLF 165
           + +Q +I  +     EEEK R+      Q A +  +E++  E+++          +K ++
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-----QEKKMW 440

Query: 166 RNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQER--KEKEKKRTQRGERK 223
           R    E+ ++    E++ +R+E +R+ EQ+++ R+ +K+ +QE   ++KEK   Q   RK
Sbjct: 441 RQ---EEKIH----EQEKIREEEKRQ-EQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492

Query: 224 R 224
           +
Sbjct: 493 Q 493



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 26/157 (16%), Positives = 79/157 (50%), Gaps = 17/157 (10%)

Query: 69  EEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRK 128
           +E+ +    ++I E+  + +    K+++++E+       E++ ++  +   + E+EK R+
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ-----EQEEKMGEQEEKMQEQEKMRR 568

Query: 129 AALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDES 188
                Q   + ++E++  E+ +     +    +K+  +   + +     + + + + ++ 
Sbjct: 569 -----QEEKIREQEEKIREQKEK----IREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619

Query: 189 QRKKEQD-KLQRERDKLAKQERK--EKEKKRTQRGER 222
           ++  EQ+ K+Q + +K+ +QE K  E+E +  Q+ E+
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 32/181 (17%), Positives = 86/181 (47%), Gaps = 18/181 (9%)

Query: 49  QEEEE----EEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIA 104
           QE+EE    EEK+   + I     +      I K+  + W + +      K  D+ + I 
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE------KMHDQEEKIR 512

Query: 105 TLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLL 164
              EK  +   K R   E+ ++++  +  Q   + ++E++  E+++          +K+ 
Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-----QEKMR 567

Query: 165 FRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERK---EKEKKRTQRGE 221
            +   + +     + +++ +R++ ++  EQ++  RE++++ +++ +   E+E+K  ++ E
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627

Query: 222 R 222
           +
Sbjct: 628 K 628


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 34/179 (18%), Positives = 93/179 (51%), Gaps = 15/179 (8%)

Query: 49  QEE---EEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIAT 105
           QEE   E+EEK+   +  +  + +E+ +    ++I E+  +      K++++DE      
Sbjct: 330 QEEKMHEQEEKIREQEDKM--WRQEEKIREQEEKIREQEEKMWRQEEKIREQDE-----K 382

Query: 106 LIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLF 165
           + E++ ++  +   + E+E++R+  +  Q   + +++++  E+++     M    +K+  
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE----MWRQEEKIRE 438

Query: 166 RNTNVEDVLNARKLERDSLRDESQRKKEQD-KLQRERDKLAKQERKEKEKKRTQRGERK 223
               ++D     +   + +++E ++ +EQ+ K+QR+ +K+ +QE K   +++  + E K
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 9/197 (4%)

Query: 31  EALGVDRAVYGAYILGILQEEEEEEKLDALQGILS--AFLEEDSLLNICKEIVERWSETQ 88
           E L  D AV     +  L +E +   L+  +  ++     E+++ L     +VE  SE  
Sbjct: 178 ETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVE--SEKS 235

Query: 89  NVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEK 148
            +   VK        A L+  Q Q+ V+   + +E +   A L AQ     +E +  +  
Sbjct: 236 EIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ----VEENELWNLL 291

Query: 149 DDSGATTMNIGSDKLLFRNTNV-EDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQ 207
           +      M    +K+  +   + E  L  R+ E    R E +  ++++K++ + DK+ +Q
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351

Query: 208 ERKEKEKKRTQRGERKR 224
           E K +E++   R + ++
Sbjct: 352 EEKIREQEEKIREQEEK 368



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 32/167 (19%), Positives = 80/167 (47%), Gaps = 30/167 (17%)

Query: 51  EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQ 110
           E+EE++ + +        E+D  +   +E  E W          ++E++++ +  +++ Q
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEE--EMW----------RQEEKIRELEEMMQDQ 446

Query: 111 AQIV--VKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNT 168
            + +  V+ +M  EEEK ++     Q   +  +E++  E+++          +KLL +  
Sbjct: 447 EEKLREVEEKMQEEEEKMQE-----QEEKIQRQEEKIQEQEEK-----TWRQEKLLKQEE 496

Query: 169 NVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKK 215
            + +       E    R E +  ++++K+Q + +K+ +QE K +E++
Sbjct: 497 KIWEQ------EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 32/158 (20%), Positives = 72/158 (45%), Gaps = 23/158 (14%)

Query: 86  ETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEK--QRKAALLAQYADVTDEED 143
           E Q+V  K++ + E   +  L+ +Q +     +M  +EEK  +++  +  Q   + ++E+
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQE----EKMWRQEEKIQEQEEKMCEQELKIREQEE 325

Query: 144 EA---DEKDDSGATTMNIGSDKLLFRNTNV-EDVLNARKLERDSLRDESQRKKEQDKLQR 199
           +    +EK       +    DK+  +   + E     R+ E    R E + +++ +K+Q 
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385

Query: 200 ERDKLAKQERK-------------EKEKKRTQRGERKR 224
           + +++ +QE K              +EKK  ++ E+ R
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 34/179 (18%), Positives = 93/179 (51%), Gaps = 15/179 (8%)

Query: 49  QEE---EEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIAT 105
           QEE   E+EEK+   +  +  + +E+ +    ++I E+  +      K++++DE      
Sbjct: 330 QEEKMHEQEEKIREQEDKM--WRQEEKIREQEEKIREQEEKMWRQEEKIREQDE-----K 382

Query: 106 LIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLF 165
           + E++ ++  +   + E+E++R+  +  Q   + +++++  E+++     M    +K+  
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE----MWRQEEKIRE 438

Query: 166 RNTNVEDVLNARKLERDSLRDESQRKKEQD-KLQRERDKLAKQERKEKEKKRTQRGERK 223
               ++D     +   + +++E ++ +EQ+ K+QR+ +K+ +QE K   +++  + E K
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 9/197 (4%)

Query: 31  EALGVDRAVYGAYILGILQEEEEEEKLDALQGILS--AFLEEDSLLNICKEIVERWSETQ 88
           E L  D AV     +  L +E +   L+  +  ++     E+++ L     +VE  SE  
Sbjct: 178 ETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVE--SEKS 235

Query: 89  NVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEK 148
            +   VK        A L+  Q Q+ V+   + +E +   A L AQ     +E +  +  
Sbjct: 236 EIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ----VEENELWNLL 291

Query: 149 DDSGATTMNIGSDKLLFRNTNV-EDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQ 207
           +      M    +K+  +   + E  L  R+ E    R E +  ++++K++ + DK+ +Q
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351

Query: 208 ERKEKEKKRTQRGERKR 224
           E K +E++   R + ++
Sbjct: 352 EEKIREQEEKIREQEEK 368



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 32/167 (19%), Positives = 80/167 (47%), Gaps = 30/167 (17%)

Query: 51  EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQ 110
           E+EE++ + +        E+D  +   +E  E W          ++E++++ +  +++ Q
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEE--EMW----------RQEEKIRELEEMMQDQ 446

Query: 111 AQIV--VKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNT 168
            + +  V+ +M  EEEK ++     Q   +  +E++  E+++          +KLL +  
Sbjct: 447 EEKLREVEEKMQEEEEKMQE-----QEEKIQRQEEKIQEQEEK-----TWRQEKLLKQEE 496

Query: 169 NVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKK 215
            + +       E    R E +  ++++K+Q + +K+ +QE K +E++
Sbjct: 497 KIWEQ------EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 32/158 (20%), Positives = 72/158 (45%), Gaps = 23/158 (14%)

Query: 86  ETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEK--QRKAALLAQYADVTDEED 143
           E Q+V  K++ + E   +  L+ +Q +     +M  +EEK  +++  +  Q   + ++E+
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQE----EKMWRQEEKIQEQEEKMCEQELKIREQEE 325

Query: 144 EA---DEKDDSGATTMNIGSDKLLFRNTNV-EDVLNARKLERDSLRDESQRKKEQDKLQR 199
           +    +EK       +    DK+  +   + E     R+ E    R E + +++ +K+Q 
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385

Query: 200 ERDKLAKQERK-------------EKEKKRTQRGERKR 224
           + +++ +QE K              +EKK  ++ E+ R
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.129    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,559,225
Number of Sequences: 37866
Number of extensions: 425667
Number of successful extensions: 9988
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 323
Number of HSP's successfully gapped in prelim test: 505
Number of HSP's that attempted gapping in prelim test: 4868
Number of HSP's gapped (non-prelim): 3429
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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