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Search of human proteins with 151101292
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
(280 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151101292 thioredoxin domain containing 1 [Homo sapiens] 585 e-167
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa... 222 3e-58
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 69 6e-12
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 67 1e-11
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 65 7e-11
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 63 3e-10
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 62 7e-10
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 60 2e-09
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 54 2e-07
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 54 2e-07
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 53 3e-07
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 53 3e-07
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 46 4e-05
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 41 0.001
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi... 40 0.002
gi|54633317 thioredoxin domain containing 11 [Homo sapiens] 39 0.007
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa... 38 0.011
gi|95113651 glutaredoxin 3 [Homo sapiens] 37 0.019
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 36 0.033
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 36 0.033
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens] 35 0.096
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap... 35 0.096
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap... 35 0.096
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens] 33 0.21
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens] 33 0.21
gi|118600967 shroom family member 4 [Homo sapiens] 33 0.28
gi|4504425 high-mobility group box 1 [Homo sapiens] 33 0.28
gi|55741677 SET domain containing 1A [Homo sapiens] 33 0.28
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 33 0.28
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 33 0.28
>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
Length = 280
Score = 585 bits (1508), Expect = e-167
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 1 MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQ 60
MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQ
Sbjct: 1 MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQ 60
Query: 61 NLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTK 120
NLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTK
Sbjct: 61 NLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTK 120
Query: 121 KDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGS 180
KDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGS
Sbjct: 121 KDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGS 180
Query: 181 YTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQE 240
YTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQE
Sbjct: 181 YTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQE 240
Query: 241 ADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS 280
ADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS
Sbjct: 241 ADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS 280
>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
sapiens]
Length = 349
Score = 222 bits (565), Expect = 3e-58
Identities = 102/234 (43%), Positives = 152/234 (64%), Gaps = 12/234 (5%)
Query: 28 RSNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTE 87
+S V+ +T NW ++EG+WM++FYAPWCP+CQ EWE+FA+ GE L++++ KVDV +
Sbjct: 36 QSRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQ 95
Query: 88 QPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSV 147
+PGLSGRF +T LP +H KDG FRRY+GP +D N+I +K+W+S+EP++ W P S+
Sbjct: 96 EPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASL 155
Query: 148 LMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFVADCLC 207
MS M+ LF +S I HNYF LG+P W SY F +ATL GL +GL ++ +++C
Sbjct: 156 TMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLVLVVISEC-- 213
Query: 208 PSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADE-EDVSEEEAESKEGTNKD 260
+ P + LSE ++ ++ EE A++ +D EE+ +S E NKD
Sbjct: 214 ---------FYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKD 258
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 68.6 bits (166), Expect = 6e-12
Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 9/111 (8%)
Query: 36 DENWRELLEGD-WMIEFYAPWCPACQNLQPEWESFAEWGEDLE-----VNIAKVDVTEQP 89
DE+++E D W+++FYAPWC C+ L+P W E G +++ V + K+D T
Sbjct: 32 DESFKENRNDDIWLVDFYAPWCGHCKKLEPIWN---EVGLEMKSIGSPVKVGKMDATSYS 88
Query: 90 GLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSS 140
++ F + PTI K Y+GPRTK D I F I P+ S
Sbjct: 89 SIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPS 139
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 67.4 bits (163), Expect = 1e-11
Identities = 38/105 (36%), Positives = 62/105 (59%), Gaps = 7/105 (6%)
Query: 28 RSNVRVITDENW-RELLEGD--WMIEFYAPWCPACQNLQPEWESFAEWGEDL---EVNIA 81
+ +V +TD+++ + +L+ + WM+EFYAPWC C+NL+PEW + A ++ +V +A
Sbjct: 159 KKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLA 218
Query: 82 KVDVTEQPGLSGRFIITALPTIYHCKDGEFR-RYQGPRTKKDFIN 125
VD T L+ R+ I PTI + GE Y G RT+ D ++
Sbjct: 219 AVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 263
Score = 62.4 bits (150), Expect = 4e-10
Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 6/97 (6%)
Query: 34 ITDENW-RELLEGD--WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPG 90
+T N+ RE+++ D W++EFYAPWC CQ L PEW+ A +D+ V + VD +
Sbjct: 30 LTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDV-VKVGAVDADKHHS 88
Query: 91 LSGRFIITALPT--IYHCKDGEFRRYQGPRTKKDFIN 125
L G++ + PT I+ YQG RT + ++
Sbjct: 89 LGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVD 125
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 65.1 bits (157), Expect = 7e-11
Identities = 35/111 (31%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
Query: 29 SNVRVITDENWRELL--EGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLE--VNIAKVD 84
+ V V+ D N+ + + ++EFYAPWC C+ PE+E A +D + + +AK+D
Sbjct: 62 NGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKID 121
Query: 85 VTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDF---INFISDKEW 132
T L+ RF ++ PTI K G+ Y+G RT+++ + +S +W
Sbjct: 122 ATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDW 172
Score = 63.2 bits (152), Expect = 3e-10
Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Query: 33 VITDENWRELLEGD--WMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIAKVDVTEQ 88
V+T EN+ E++ ++EFYAPWC C+ L PE+E A+ + +AKVD T +
Sbjct: 181 VLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAE 240
Query: 89 PGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDK 130
L+ RF ++ PT+ + G Y GPR K ++++ ++
Sbjct: 241 TDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQ 282
Score = 52.4 bits (124), Expect = 4e-07
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 22 PWTHGRRSNVRVITDENWRELL---EGDWMIEFYAPWCPACQNLQPEWESFA-EWGEDLE 77
P + V+V+ + + ++ + D +IEFYAPWC C+ L+P + S A ++
Sbjct: 518 PVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKG 577
Query: 78 VNIAKVDVTEQPGLSGRFIITALPTIYHCKDGE 110
+ IAK+D T S R+ + PTIY G+
Sbjct: 578 LVIAKMDATANDVPSDRYKVEGFPTIYFAPSGD 610
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 63.2 bits (152), Expect = 3e-10
Identities = 36/104 (34%), Positives = 59/104 (56%), Gaps = 8/104 (7%)
Query: 31 VRVITDENWRELLEG---DWMIEFYAPWCPACQNLQPEWESFAE-WGEDLEVNIAKVDVT 86
V+V+ EN+ E++ D +IEFYAPWC C+NL+P+++ E +D + IAK+D T
Sbjct: 378 VKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDAT 437
Query: 87 EQPGLSGRFIITALPTIYHC---KDGEFRRYQGPRTKKDFINFI 127
+ + + PTIY K ++Y+G R DFI+++
Sbjct: 438 AN-DVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL 480
Score = 60.1 bits (144), Expect = 2e-09
Identities = 35/116 (30%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Query: 29 SNVRVITDENWRELLE-----GDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKV 83
S+V +TD+N+ + G ++EF+APWC C+ L PE+E+ A + + V +AKV
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGI-VPLAKV 83
Query: 84 DVTEQPGLSGRFIITALPTIYHCKDG-EFRRYQGPRTKKDFINFISDKEWKSIEPV 138
D T ++ ++ PT+ +DG E Y GPRT ++ + + + P+
Sbjct: 84 DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPL 139
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 61.6 bits (148), Expect = 7e-10
Identities = 39/115 (33%), Positives = 63/115 (54%), Gaps = 6/115 (5%)
Query: 22 PWTHGRRSNVRVITDENWRELLE--GDWMIEFYAPWCPACQNLQPEWESFAE--WGE-DL 76
PW +V +TDE++ + ++ ++ F+APWC C+ ++PE+E AE GE D
Sbjct: 270 PWAD-EGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADS 328
Query: 77 EVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKE 131
+A VD T L+ RF I+ PT+ + K+GE RTKK F+ ++ + E
Sbjct: 329 SGVLAAVDATVNKALAERFHISEFPTLKYFKNGEKYAVPVLRTKKKFLEWMQNPE 383
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 6/112 (5%)
Query: 22 PWTHGRRSNVRVITDENWRELLEGD--WMIEFYAPWCPACQNLQPEWESFAE-WGEDLEV 78
P ++++V + +N+RE L+ ++ FYAPWCP C+ + P + + A+ + +D ++
Sbjct: 390 PTWEEQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKI 449
Query: 79 NIAKVDVTEQPG--LSGRFIITALPTIYHCKDGEF-RRYQGPRTKKDFINFI 127
A VD + L + + PT ++ G+F +Y RT+ F N+I
Sbjct: 450 ACAAVDCVKDKNQDLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTELGFTNYI 501
Score = 38.9 bits (89), Expect = 0.005
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Query: 26 GRRSNVRVITDENWRELL---EGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAK 82
G + V + +++++R LL E +I FYAPWC C+ + P ++ A V +A
Sbjct: 149 GAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAV-LAG 207
Query: 83 VDV--TEQPGLSGRFIITALPTIYHCKDGEF 111
++V +E + + + PTI + + G F
Sbjct: 208 MNVYSSEFENIKEEYSVRGFPTICYFEKGRF 238
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 60.5 bits (145), Expect = 2e-09
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
Query: 11 LAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGD--WMIEFYAPWCPACQNLQPEWES 68
LAV L+ AP +V V+ N+ E L ++EFYAPWC C+ L PE+
Sbjct: 9 LAVAALVRADAP---EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAK 65
Query: 69 FAE--WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEF---RRYQGPRTKKDF 123
A E E+ +AKVD TE+ L+ ++ + PTI ++G+ + Y R D
Sbjct: 66 AAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDI 125
Query: 124 INFISDK 130
+N++ +
Sbjct: 126 VNWLKKR 132
Score = 44.7 bits (104), Expect = 9e-05
Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 31 VRVITDENWRELL---EGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLE-VNIAKVDVT 86
V+V+ +N+ ++ + + +EFYAPWC C+ L P W+ E +D E + IAK+D T
Sbjct: 369 VKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDST 428
Query: 87 EQPGLSGRFIITALPTIYH---CKDGEFRRYQGPRTKKDFINFI 127
+ + + + PT+ D Y G RT F F+
Sbjct: 429 ANEVEAVK--VHSFPTLKFFPASADRTVIDYNGERTLDGFKKFL 470
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 53.9 bits (128), Expect = 2e-07
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 29 SNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIAKVDVT 86
S+V + +N+ + W+++F+APWCP C+ L PE + +G ++ +D T
Sbjct: 453 SHVTTLGPQNFPANDKEPWLVDFFAPWCPPCRALLPELRRASNLLYG---QLKFGTLDCT 509
Query: 87 EQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISD 129
GL + I A PT Y+G + + + FI D
Sbjct: 510 VHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFIED 552
Score = 45.8 bits (107), Expect = 4e-05
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 47 WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTI 103
WM++FY+PWC CQ L PEW+ A L +N+ +D + + + P I
Sbjct: 579 WMVDFYSPWCHPCQVLMPEWKRMARTLTGL-INVGSIDCQQYHSFCAQENVQRYPEI 634
Score = 45.4 bits (106), Expect = 5e-05
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 47 WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTI 103
W+I+FYAPWC CQN PE+E A + +V KVD + I A PT+
Sbjct: 691 WVIDFYAPWCGPCQNFAPEFELLARMIKG-KVKAGKVDCQAYAQTCQKAGIRAYPTV 746
Score = 43.1 bits (100), Expect = 3e-04
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 47 WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
W + FY+P C C +L P W FA+ + L + I V+ + L + + P+++
Sbjct: 149 WFVNFYSPGCSHCHDLAPTWRDFAKEVDGL-LRIGAVNCGDDRMLCRMKGVNSYPSLFIF 207
Query: 107 KDGEFR-RYQGPRTKKDFINF 126
+ G +Y G R+K+ ++F
Sbjct: 208 RSGMAPVKYHGDRSKESLVSF 228
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 53.5 bits (127), Expect = 2e-07
Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 27/135 (20%)
Query: 9 VPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGD--------------------WM 48
+P+ +L+LL PW G+ R ++E E + + +
Sbjct: 6 LPVLLLLLLRASCPW--GQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALL 63
Query: 49 IEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
+EFYAPWC CQ L PE+ A E + V +AKVD Q L+ F +T PT+
Sbjct: 64 VEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFF 123
Query: 107 KDGEF---RRYQGPR 118
++G Y GPR
Sbjct: 124 RNGNRTHPEEYTGPR 138
Score = 48.5 bits (114), Expect = 6e-06
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 49 IEFYAPWCPACQNLQPEWESFAEWGEDLE-VNIAKVDVTEQPGLSGRFIITALPTIYHCK 107
++FYAPWC C+ + P WE+ AE +D E + IA++D T F + PT+ +
Sbjct: 411 VKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANE--LDAFAVHGFPTLKYFP 468
Query: 108 DGEFRR---YQGPRTKKDFINFISD 129
G R+ Y+ R + F F+ +
Sbjct: 469 AGPGRKVIEYKSTRDLETFSKFLDN 493
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
Query: 49 IEFYAPWCPACQNLQPEWESFAE---WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYH 105
+ F+APWC CQ LQP W + ED +V +AKVD T + + PT+
Sbjct: 82 VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKL 141
Query: 106 CKDG-EFRRYQGPRTKKDFINFI 127
K G E +YQGPR + N++
Sbjct: 142 FKPGQEAVKYQGPRDFQTLENWM 164
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 44 EGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLE-VNIAKVDVTEQPGLSGRFIITALPT 102
+GD I+F+APWC C+ L P WE A E E V I KVD T+ L + PT
Sbjct: 205 QGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPT 264
Query: 103 IYHCKDG-EFRRYQGPRTKKDFINFISDK 130
+ +DG + +Y+G R + ++ +
Sbjct: 265 LLWFRDGKKVDQYKGKRDLESLREYVESQ 293
Score = 52.8 bits (125), Expect = 3e-07
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 28 RSNVRVITDENWRELL-EGDWMIEFYAPWCPACQNLQPEWESFA--EWGEDLEVNIAKVD 84
+ V +T+ N+ + + EG I+FYAPWC C+ L P WE + E+ V IA+VD
Sbjct: 321 KGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVD 380
Query: 85 VTEQPGLSGRFIITALPTIYHCKDGE 110
T + + ++ + PT+ + G+
Sbjct: 381 CTAERNICSKYSVRGYPTLLLFRGGK 406
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 44 EGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLE-VNIAKVDVTEQPGLSGRFIITALPT 102
+GD I+F+APWC C+ L P WE A E E V I KVD T+ L + PT
Sbjct: 97 QGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPT 156
Query: 103 IYHCKDG-EFRRYQGPRTKKDFINFISDK 130
+ +DG + +Y+G R + ++ +
Sbjct: 157 LLWFRDGKKVDQYKGKRDLESLREYVESQ 185
Score = 52.8 bits (125), Expect = 3e-07
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 28 RSNVRVITDENWRELL-EGDWMIEFYAPWCPACQNLQPEWESFA--EWGEDLEVNIAKVD 84
+ V +T+ N+ + + EG I+FYAPWC C+ L P WE + E+ V IA+VD
Sbjct: 213 KGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVD 272
Query: 85 VTEQPGLSGRFIITALPTIYHCKDGE 110
T + + ++ + PT+ + G+
Sbjct: 273 CTAERNICSKYSVRGYPTLLLFRGGK 298
Score = 30.4 bits (67), Expect = 1.8
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 74 EDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDG-EFRRYQGPRTKKDFINFI 127
ED +V +AKVD T + + PT+ K G E +YQGPR + N++
Sbjct: 2 EDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWM 56
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 45.8 bits (107), Expect = 4e-05
Identities = 39/151 (25%), Positives = 74/151 (49%), Gaps = 17/151 (11%)
Query: 1 MAPSGSLAVP---LAVLVLLLWG-APWTHGRRSNVRVITDENWRELLEGD--WMIEFYAP 54
M P+ L++P ++L+L+ W P T + + + EN E+L ++ FYA
Sbjct: 1 MHPAVFLSLPDLRCSLLLLVTWVFTPVT----TEITSLDTENIDEILNNADVALVNFYAD 56
Query: 55 WCPACQNLQPEWESFA-----EWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDG 109
WC Q L P +E + E+ + +V A+VD + ++ R+ I+ PT+ ++G
Sbjct: 57 WCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Query: 110 EF--RRYQGPRTKKDFINFISDKEWKSIEPV 138
R Y+G R+ K ++I ++ I+ +
Sbjct: 117 MMMKREYRGQRSVKALADYIRQQKSDPIQEI 147
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 40.8 bits (94), Expect = 0.001
Identities = 19/63 (30%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Query: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCK 107
+++F+A WC C+ L P E + +V +AKVD+ + L+ + ++A+PT+ K
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVA-KQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMK 140
Query: 108 DGE 110
+G+
Sbjct: 141 NGD 143
>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
sapiens]
Length = 296
Score = 40.0 bits (92), Expect = 0.002
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 5 GSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGD----WMIEFYAPWCPACQ 60
G L + L ++ L+ P G ++ D+ E LE D W++EF+A W CQ
Sbjct: 113 GLLYITLCIVFLMTCKPPLYMGPEY-IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQ 171
Query: 61 NLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALP 101
+ P + + +N KVDV +S R+ ++ P
Sbjct: 172 SFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSP 212
>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
Length = 958
Score = 38.5 bits (88), Expect = 0.007
Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 8/75 (10%)
Query: 33 VITDENWRELLEG-DWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVN---IAKVDVTEQ 88
V TD W +L+ D ++ +YAPWC C +L F + +L ++ +A++DV+ Q
Sbjct: 668 VTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLN---HIFIQLARNLPMDTFTVARIDVS-Q 723
Query: 89 PGLSGRFIITALPTI 103
L F++ LPT+
Sbjct: 724 NDLPWEFMVDRLPTV 738
>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
sapiens]
Length = 258
Score = 37.7 bits (86), Expect = 0.011
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
Query: 31 VRVITDENWRELLEGD----WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVT 86
++ D+ E LE D W++EF+A W CQ+ P + + +N KVDV
Sbjct: 100 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVG 159
Query: 87 EQPGLSGRFIITALP 101
+S R+ ++ P
Sbjct: 160 RYTDVSTRYKVSTSP 174
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 37.0 bits (84), Expect = 0.019
Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
Query: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL-EVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
++ F+APW P C + E AE ++L +V+ K++ P +S ++ I+++PT
Sbjct: 35 VVHFWAPWAPQCAQMN---EVMAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPTFLFF 91
Query: 107 KDGE 110
K+ +
Sbjct: 92 KNSQ 95
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 36.2 bits (82), Expect = 0.033
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 212 RRPQPYPYPSKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKDFPQNAIRQRSL 271
R P + P KK ES + L++ EEE+E +EE EEE E +E ++ + + + +
Sbjct: 5 RSPSGFGDPGKKDQKESEEELEEEEEEEEVEEE---EEEVEEEEEEVEEEEEEVVEEELV 61
Query: 272 G 272
G
Sbjct: 62 G 62
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 36.2 bits (82), Expect = 0.033
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 210 KRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKE 255
K RP+ YP KK E + K EEE+E +EE+ EEE E +E
Sbjct: 1747 KEDRPEHYPGLGKK---EEGEEEKGEEEEEELEEEEEEEEETEEEE 1789
>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
Length = 698
Score = 34.7 bits (78), Expect = 0.096
Identities = 13/46 (28%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
Query: 47 WMIEFYAPWCPACQNLQPEWESFA----EWGEDLEVNIAKVDVTEQ 88
W+++FY+ WC C P W + A +W + +A +D E+
Sbjct: 82 WLVQFYSSWCGHCIGYAPTWRALAGDVRDWAS--AIRVAALDCMEE 125
>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
sapiens]
Length = 604
Score = 34.7 bits (78), Expect = 0.096
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 47 WMIEFYAPWCPACQNLQPEWESFAE----WGEDLEVNIAKVDVTEQ--PGLSGRFIITAL 100
W +EF+A WC C P W++ AE W L +A +D E+ + F I
Sbjct: 61 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPAL--YLAALDCAEETNSAVCRDFNIPGF 118
Query: 101 PTI 103
PT+
Sbjct: 119 PTV 121
>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
sapiens]
Length = 747
Score = 34.7 bits (78), Expect = 0.096
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 47 WMIEFYAPWCPACQNLQPEWESFAE----WGEDLEVNIAKVDVTEQ--PGLSGRFIITAL 100
W +EF+A WC C P W++ AE W L +A +D E+ + F I
Sbjct: 61 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPAL--YLAALDCAEETNSAVCRDFNIPGF 118
Query: 101 PTI 103
PT+
Sbjct: 119 PTV 121
>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
Length = 981
Score = 33.5 bits (75), Expect = 0.21
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 18/65 (27%)
Query: 225 LSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKD------------------FPQNAI 266
L+ + P++ E++ ++EE+ EEE ES++G +D PQNA
Sbjct: 908 LTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNAT 967
Query: 267 RQRSL 271
RQ+ L
Sbjct: 968 RQQQL 972
>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
Length = 971
Score = 33.5 bits (75), Expect = 0.21
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 18/65 (27%)
Query: 225 LSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKD------------------FPQNAI 266
L+ + P++ E++ ++EE+ EEE ES++G +D PQNA
Sbjct: 898 LTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNAT 957
Query: 267 RQRSL 271
RQ+ L
Sbjct: 958 RQQQL 962
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 33.1 bits (74), Expect = 0.28
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 12/82 (14%)
Query: 203 ADCLCPSKRRRPQPYPYP---SKKLLSESAQPLKKV---------EEEQEADEEDVSEEE 250
+D L K+ P P P P K L +AQ K+ EEE+E +EE+ EEE
Sbjct: 1089 SDLLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEE 1148
Query: 251 AESKEGTNKDFPQNAIRQRSLG 272
E E ++ P + G
Sbjct: 1149 EEEAEEEEEELPPQYFSSETSG 1170
>gi|4504425 high-mobility group box 1 [Homo sapiens]
Length = 215
Score = 33.1 bits (74), Expect = 0.28
Identities = 16/28 (57%), Positives = 17/28 (60%)
Query: 233 KKVEEEQEADEEDVSEEEAESKEGTNKD 260
KK EEE E DEED EEE E E +D
Sbjct: 184 KKEEEEDEEDEEDEEEEEDEEDEDEEED 211
Score = 29.6 bits (65), Expect = 3.1
Identities = 15/35 (42%), Positives = 19/35 (54%)
Query: 221 SKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKE 255
SKK E + +EE+E DEED EEE + E
Sbjct: 181 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 215
Score = 28.9 bits (63), Expect = 5.2
Identities = 12/32 (37%), Positives = 22/32 (68%)
Query: 229 AQPLKKVEEEQEADEEDVSEEEAESKEGTNKD 260
A+ KK +EE+E +E++ EEE E +E +++
Sbjct: 178 AEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEE 209
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 33.1 bits (74), Expect = 0.28
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 19/79 (24%)
Query: 212 RRPQPYPYPS--------------KKLLSESAQPL-----KKVEEEQEADEEDVSEEEAE 252
R P+P P P+ + +++E+ +P ++ EE +E EE+ EEE E
Sbjct: 1316 RPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEE 1375
Query: 253 SKEGTNKDFPQNAIRQRSL 271
S + ++ + A+R+RSL
Sbjct: 1376 SSDSSSSSDGEGALRRRSL 1394
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 33.1 bits (74), Expect = 0.28
Identities = 19/59 (32%), Positives = 30/59 (50%)
Query: 221 SKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDK 279
SK + + L + EEE+E +EE+ EEE E +E +++ + R S G A K
Sbjct: 287 SKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKK 345
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 33.1 bits (74), Expect = 0.28
Identities = 19/59 (32%), Positives = 30/59 (50%)
Query: 221 SKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDK 279
SK + + L + EEE+E +EE+ EEE E +E +++ + R S G A K
Sbjct: 287 SKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKK 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,020,612
Number of Sequences: 37866
Number of extensions: 572926
Number of successful extensions: 7947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 6018
Number of HSP's gapped (non-prelim): 1226
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.