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Search of human proteins with 110347427
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
(3546 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 7212 0.0
gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [... 261 9e-69
gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [... 261 9e-69
gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens] 256 2e-67
gi|149192845 ubiquitin specific protease 24 [Homo sapiens] 248 6e-65
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 145 5e-34
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 145 5e-34
gi|71774197 ubiquitin specific protease 47 [Homo sapiens] 132 5e-30
gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 123 3e-27
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 123 3e-27
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 100 3e-20
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 100 3e-20
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 96 6e-19
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 95 1e-18
gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 90 3e-17
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 88 2e-16
gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 86 5e-16
gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sap... 86 5e-16
gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 85 1e-15
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 85 1e-15
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 84 2e-15
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 84 2e-15
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 84 2e-15
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 81 2e-14
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 80 4e-14
gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo ... 80 4e-14
gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ... 80 4e-14
gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ... 80 5e-14
gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ... 80 5e-14
gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ... 80 5e-14
>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
Length = 3546
Score = 7212 bits (18711), Expect = 0.0
Identities = 3546/3546 (100%), Positives = 3546/3546 (100%)
Query: 1 MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFN 60
MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFN
Sbjct: 1 MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFN 60
Query: 61 QVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPLNIDRECNEGSTERQK 120
QVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPLNIDRECNEGSTERQK
Sbjct: 61 QVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPLNIDRECNEGSTERQK 120
Query: 121 SIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH 180
SIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH
Sbjct: 121 SIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH 180
Query: 181 PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFL 240
PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFL
Sbjct: 181 PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFL 240
Query: 241 IAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTV 300
IAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTV
Sbjct: 241 IAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTV 300
Query: 301 KEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS 360
KEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS
Sbjct: 301 KEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS 360
Query: 361 IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH 420
IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH
Sbjct: 361 IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH 420
Query: 421 CSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKA 480
CSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKA
Sbjct: 421 CSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKA 480
Query: 481 QLSKQSSFASLLNTNIPIGNKKEEEELRRTAPSPWSPAASPQSSDNSDTHQSGGSDIEMD 540
QLSKQSSFASLLNTNIPIGNKKEEEELRRTAPSPWSPAASPQSSDNSDTHQSGGSDIEMD
Sbjct: 481 QLSKQSSFASLLNTNIPIGNKKEEEELRRTAPSPWSPAASPQSSDNSDTHQSGGSDIEMD 540
Query: 541 EQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQ 600
EQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQ
Sbjct: 541 EQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQ 600
Query: 601 SAGSPGSEVQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQG 660
SAGSPGSEVQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQG
Sbjct: 601 SAGSPGSEVQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQG 660
Query: 661 MSERNGTSSGTGKDLVFNTESLPSVDNRMRMLDACSHSEDPEHDISGEMNATHIAQGSQE 720
MSERNGTSSGTGKDLVFNTESLPSVDNRMRMLDACSHSEDPEHDISGEMNATHIAQGSQE
Sbjct: 661 MSERNGTSSGTGKDLVFNTESLPSVDNRMRMLDACSHSEDPEHDISGEMNATHIAQGSQE 720
Query: 721 SCITRTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQ 780
SCITRTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQ
Sbjct: 721 SCITRTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQ 780
Query: 781 VSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPVVHKH 840
VSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPVVHKH
Sbjct: 781 VSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPVVHKH 840
Query: 841 QFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEAEKLLCSLVCWFTDRQIR 900
QFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEAEKLLCSLVCWFTDRQIR
Sbjct: 841 QFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEAEKLLCSLVCWFTDRQIR 900
Query: 901 MRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDN 960
MRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDN
Sbjct: 901 MRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDN 960
Query: 961 LVYYIQTVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVE 1020
LVYYIQTVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVE
Sbjct: 961 LVYYIQTVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVE 1020
Query: 1021 DSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLA 1080
DSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLA
Sbjct: 1021 DSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLA 1080
Query: 1081 RLATSAYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFIS 1140
RLATSAYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFIS
Sbjct: 1081 RLATSAYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFIS 1140
Query: 1141 KCMESLMIASSSLEQESHSSLMVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHL 1200
KCMESLMIASSSLEQESHSSLMVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHL
Sbjct: 1141 KCMESLMIASSSLEQESHSSLMVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHL 1200
Query: 1201 KALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQ 1260
KALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQ
Sbjct: 1201 KALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQ 1260
Query: 1261 EFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERK 1320
EFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERK
Sbjct: 1261 EFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERK 1320
Query: 1321 GEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKVAVDDSESLRC 1380
GEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKVAVDDSESLRC
Sbjct: 1321 GEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKVAVDDSESLRC 1380
Query: 1381 EELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGFNWKELLKIKSAHKLLYA 1440
EELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGFNWKELLKIKSAHKLLYA
Sbjct: 1381 EELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGFNWKELLKIKSAHKLLYA 1440
Query: 1441 LEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEI 1500
LEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEI
Sbjct: 1441 LEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEI 1500
Query: 1501 FNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRT 1560
FNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRT
Sbjct: 1501 FNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRT 1560
Query: 1561 WPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHR 1620
WPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHR
Sbjct: 1561 WPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHR 1620
Query: 1621 SRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCSGLYKL 1680
SRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCSGLYKL
Sbjct: 1621 SRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCSGLYKL 1680
Query: 1681 SLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPILKPGCKEYFWLLCK 1740
SLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPILKPGCKEYFWLLCK
Sbjct: 1681 SLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPILKPGCKEYFWLLCK 1740
Query: 1741 LVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGLTGLLRLATSVVKH 1800
LVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGLTGLLRLATSVVKH
Sbjct: 1741 LVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGLTGLLRLATSVVKH 1800
Query: 1801 KPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYR 1860
KPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYR
Sbjct: 1801 KPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYR 1860
Query: 1861 LIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQ 1920
LIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQ
Sbjct: 1861 LIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQ 1920
Query: 1921 AVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMT 1980
AVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMT
Sbjct: 1921 AVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMT 1980
Query: 1981 EFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKN 2040
EFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKN
Sbjct: 1981 EFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKN 2040
Query: 2041 IYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMK 2100
IYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMK
Sbjct: 2041 IYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMK 2100
Query: 2101 EKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTA 2160
EKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTA
Sbjct: 2101 EKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTA 2160
Query: 2161 DGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKF 2220
DGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKF
Sbjct: 2161 DGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKF 2220
Query: 2221 MDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYF 2280
MDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYF
Sbjct: 2221 MDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYF 2280
Query: 2281 GFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQ 2340
GFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQ
Sbjct: 2281 GFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQ 2340
Query: 2341 AACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDG 2400
AACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDG
Sbjct: 2341 AACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDG 2400
Query: 2401 SDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFL 2460
SDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFL
Sbjct: 2401 SDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFL 2460
Query: 2461 LSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIAL 2520
LSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIAL
Sbjct: 2461 LSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIAL 2520
Query: 2521 VALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRL 2580
VALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRL
Sbjct: 2521 VALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRL 2580
Query: 2581 AEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPS 2640
AEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPS
Sbjct: 2581 AEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPS 2640
Query: 2641 QCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQM 2700
QCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQM
Sbjct: 2641 QCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQM 2700
Query: 2701 FRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMT 2760
FRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMT
Sbjct: 2701 FRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMT 2760
Query: 2761 YCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIV 2820
YCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIV
Sbjct: 2761 YCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIV 2820
Query: 2821 QNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQW 2880
QNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQW
Sbjct: 2821 QNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQW 2880
Query: 2881 AFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRS 2940
AFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRS
Sbjct: 2881 AFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRS 2940
Query: 2941 CWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSI 3000
CWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSI
Sbjct: 2941 CWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSI 3000
Query: 3001 FLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLL 3060
FLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLL
Sbjct: 3001 FLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLL 3060
Query: 3061 SPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLL 3120
SPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLL
Sbjct: 3061 SPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLL 3120
Query: 3121 PTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPL 3180
PTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPL
Sbjct: 3121 PTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPL 3180
Query: 3181 HLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHF 3240
HLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHF
Sbjct: 3181 HLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHF 3240
Query: 3241 LLKVQSQVFSEANCANLISTLITNLISQYQNLQSDFSNRVEISKASASLNGDLRALALLL 3300
LLKVQSQVFSEANCANLISTLITNLISQYQNLQSDFSNRVEISKASASLNGDLRALALLL
Sbjct: 3241 LLKVQSQVFSEANCANLISTLITNLISQYQNLQSDFSNRVEISKASASLNGDLRALALLL 3300
Query: 3301 SVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPIKRRRVSSD 3360
SVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPIKRRRVSSD
Sbjct: 3301 SVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPIKRRRVSSD 3360
Query: 3361 EEHTVDSCISDMKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVP 3420
EEHTVDSCISDMKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVP
Sbjct: 3361 EEHTVDSCISDMKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVP 3420
Query: 3421 SSFSEDMSNIRSQHAEEQSNNGRYDDCKEFKDLHCSKDSTLAEEESEFPSTSISAVLSDL 3480
SSFSEDMSNIRSQHAEEQSNNGRYDDCKEFKDLHCSKDSTLAEEESEFPSTSISAVLSDL
Sbjct: 3421 SSFSEDMSNIRSQHAEEQSNNGRYDDCKEFKDLHCSKDSTLAEEESEFPSTSISAVLSDL 3480
Query: 3481 ADLRSCDGQALPSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGK 3540
ADLRSCDGQALPSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGK
Sbjct: 3481 ADLRSCDGQALPSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGK 3540
Query: 3541 GNQAAS 3546
GNQAAS
Sbjct: 3541 GNQAAS 3546
>gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo
sapiens]
Length = 2554
Score = 261 bits (667), Expect = 9e-69
Identities = 225/897 (25%), Positives = 369/897 (41%), Gaps = 160/897 (17%)
Query: 1833 PKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHM------QSHAPYKWDYWPHED 1886
P C S + A ++LLV + G V N + I + + + A +W+Y P
Sbjct: 1490 PVCGSPPTINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVG 1549
Query: 1887 VRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAK-------------------- 1926
R FVGL N GATCY+ S IQQLYMIP R + +
Sbjct: 1550 PRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNES 1609
Query: 1927 ----------YSEDMKHKTTLLE--------------LQKMFTYLMESECKAYNPRPFCK 1962
Y + + K L + LQ +F +L S + Y PR F K
Sbjct: 1610 NVDPRDDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWK 1669
Query: 1963 TYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNT--VKSLFGGVITNNVVSLDCEH 2020
+ + +P+N EQ D EFF L+ ++E L + + + GG + + C H
Sbjct: 1670 QFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPH 1729
Query: 2021 VSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKL 2080
+ E F T+ + + +N+ +SL++ D LEG N Y C C KKV KR KKL
Sbjct: 1730 RYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKL 1789
Query: 2081 PRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYT--------------EDFLMGK 2126
P +L+ R+ ++ K N +F FP LDM PYT E L+ +
Sbjct: 1790 PPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQ 1849
Query: 2127 SERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLF 2186
SE+ E S+ + S +Y L+GV VH+G A GGHYYS+I N + N+WY F
Sbjct: 1850 SEQSE--------SETAGSTKYRLVGVLVHSGQASGGHYYSYIIQ-RNGGDGERNRWYKF 1900
Query: 2187 NDAEV---KPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEE 2243
+D +V K D ++ ++CFGGE + +D + + ++ +AY+LFY+RM+ +
Sbjct: 1901 DDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTID 1960
Query: 2244 ENG-------------REYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSC- 2289
++ R ++ + S + + N+QF+ ++ + YF FM +L +C
Sbjct: 1961 QDDELIRYISELAITTRPHQIIMPSAIERSVRKQNVQFMHNRMQYSMEYFQFMKKLLTCN 2020
Query: 2290 ---------IPSTLPDPKAVSLMTAKLSTSFVLETFIHSKE--KPTMLQWIELLTKQFNN 2338
LP+ + +++++ +L+ F+ T H+K+ + + W + L +
Sbjct: 2021 GVYLNPPPGQDHLLPEAEEITMISIQLAARFLFTTGFHTKKVVRGSASDWYDALCILLRH 2080
Query: 2339 SQAACEWFLDR-MADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPG- 2396
S+ WF + + + L++CP+ VR F +L + + AH LQ G
Sbjct: 2081 SKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFI--------AHFSLQDGP 2132
Query: 2397 MEDGSDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEE 2456
S + S +R +L ++ V H +HL +YF +A +G E
Sbjct: 2133 CPSPFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAE 2192
Query: 2457 SQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEK 2516
LL L +T + + +GP P KY+ A L K
Sbjct: 2193 KTQLLKLSVPATFMLVSL-DEGPGPP------------------------IKYQYAELGK 2227
Query: 2517 MIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQH-------------------- 2556
+ ++V+ L+ + S L G P L Q
Sbjct: 2228 LYSVVSQLIRCCNVSSRMQSSINGNPPLPNPFGDPNLSQPIMPIQQNVADILFVRTSYVK 2287
Query: 2557 --IRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLM 2611
I D N +T L+ C N + + ++S L +A P+ LL ++
Sbjct: 2288 KIIEDCSNSEETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQIL 2344
Score = 67.8 bits (164), Expect = 2e-10
Identities = 80/321 (24%), Positives = 137/321 (42%), Gaps = 33/321 (10%)
Query: 159 LCVAKIFQIQFPLYTAYK------------HNTHPTIEDISTQESNILGAFCDMNDVEVP 206
LCVAK+ Q FPL + T P S+ + F D P
Sbjct: 158 LCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSSVQLPEDELFARSPDPRSP 217
Query: 207 LH-LLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHI 265
L+ + F NG ++ D F G+ L I A I +L + V ++
Sbjct: 218 KGWLVDLLNKFGTLNGFQILHDRFINGS--ALNVQIIAALIKPFGQCYEFLTLHTVKKYF 275
Query: 266 IPFRTYVIRYLCKLSDQELRQSA---ARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYF 322
+P V ++L L+D+EL++ A A+N A M + L + + +E++ +
Sbjct: 276 LPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFR 335
Query: 323 MSPTLTMRLAGLSQITNQLHTFNDVCNNESLVS----------DTETSIAKELADWLISN 372
+ + +RL +S +++ N+V S VS + E A+ +A+W+ N
Sbjct: 336 LK--MILRLLQISSFNGKMNALNEVNKVISSVSYYTHRHGNPEEEEWLTAERMAEWIQQN 393
Query: 373 NVVEHIFGPNLH-IEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH--CSRYIHDLF 429
N++ + +LH + +++ + IL F+ E L+ Q +D IWAA KH + +HDL
Sbjct: 394 NILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLL 453
Query: 430 PSLIKNLDPVPLRHLLNLVSA 450
L + P L HL + A
Sbjct: 454 AKLAWDFSPEQLDHLFDCFKA 474
Score = 59.3 bits (142), Expect = 7e-08
Identities = 75/329 (22%), Positives = 136/329 (41%), Gaps = 45/329 (13%)
Query: 862 LLWDIVQDEDA-VNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVI- 919
LLW++ +D V++ + ++ K+L D Q ++++I+ +E L N VI
Sbjct: 510 LLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQ-KIQWIDRFIEELRTNDKWVIP 568
Query: 920 ---SLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMK-------LFFDNLVYYIQTVR 969
+R + LFG Q S + +N ++ L +NL Y++++R
Sbjct: 569 ALKQIREICSLFGEAPQNLSQTQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMR 628
Query: 970 EGRQKH-----------ALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCL 1018
+ H + YSH EVQ RL FL + L Q +W CL
Sbjct: 629 LYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLL----KDGQLWLCAPQAKQIWKCL 684
Query: 1019 VEDSE--CYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHL 1076
E++ C +A + +++ D+ + + K F + QL P ++ G+ F+
Sbjct: 685 AENAVYLCDREACFKWYSKLMG-DEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERF 743
Query: 1077 -----CNLARLATS--AYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGK 1129
C +L AY + EL G+D W + +++ + D++ AI + Y N
Sbjct: 744 FKAVNCREGKLVAKRRAY-MMDDLELIGLDYLWRVVIQS-NDDIASRAIDLLKEIYTNLG 801
Query: 1130 TGLEKEQ-----EFISKCMESLMIASSSL 1153
L+ Q +FI C + L + +L
Sbjct: 802 PRLQVNQVVIHEDFIQSCFDRLKASYDTL 830
>gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo
sapiens]
Length = 2570
Score = 261 bits (667), Expect = 9e-69
Identities = 225/897 (25%), Positives = 369/897 (41%), Gaps = 160/897 (17%)
Query: 1833 PKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHM------QSHAPYKWDYWPHED 1886
P C S + A ++LLV + G V N + I + + + A +W+Y P
Sbjct: 1490 PVCGSPPTINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVG 1549
Query: 1887 VRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAK-------------------- 1926
R FVGL N GATCY+ S IQQLYMIP R + +
Sbjct: 1550 PRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNES 1609
Query: 1927 ----------YSEDMKHKTTLLE--------------LQKMFTYLMESECKAYNPRPFCK 1962
Y + + K L + LQ +F +L S + Y PR F K
Sbjct: 1610 NVDPRDDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWK 1669
Query: 1963 TYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNT--VKSLFGGVITNNVVSLDCEH 2020
+ + +P+N EQ D EFF L+ ++E L + + + GG + + C H
Sbjct: 1670 QFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPH 1729
Query: 2021 VSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKL 2080
+ E F T+ + + +N+ +SL++ D LEG N Y C C KKV KR KKL
Sbjct: 1730 RYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKL 1789
Query: 2081 PRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYT--------------EDFLMGK 2126
P +L+ R+ ++ K N +F FP LDM PYT E L+ +
Sbjct: 1790 PPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQ 1849
Query: 2127 SERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLF 2186
SE+ E S+ + S +Y L+GV VH+G A GGHYYS+I N + N+WY F
Sbjct: 1850 SEQSE--------SETAGSTKYRLVGVLVHSGQASGGHYYSYIIQ-RNGGDGERNRWYKF 1900
Query: 2187 NDAEV---KPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEE 2243
+D +V K D ++ ++CFGGE + +D + + ++ +AY+LFY+RM+ +
Sbjct: 1901 DDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTID 1960
Query: 2244 ENG-------------REYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSC- 2289
++ R ++ + S + + N+QF+ ++ + YF FM +L +C
Sbjct: 1961 QDDELIRYISELAITTRPHQIIMPSAIERSVRKQNVQFMHNRMQYSMEYFQFMKKLLTCN 2020
Query: 2290 ---------IPSTLPDPKAVSLMTAKLSTSFVLETFIHSKE--KPTMLQWIELLTKQFNN 2338
LP+ + +++++ +L+ F+ T H+K+ + + W + L +
Sbjct: 2021 GVYLNPPPGQDHLLPEAEEITMISIQLAARFLFTTGFHTKKVVRGSASDWYDALCILLRH 2080
Query: 2339 SQAACEWFLDR-MADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPG- 2396
S+ WF + + + L++CP+ VR F +L + + AH LQ G
Sbjct: 2081 SKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFI--------AHFSLQDGP 2132
Query: 2397 MEDGSDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEE 2456
S + S +R +L ++ V H +HL +YF +A +G E
Sbjct: 2133 CPSPFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAE 2192
Query: 2457 SQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEK 2516
LL L +T + + +GP P KY+ A L K
Sbjct: 2193 KTQLLKLSVPATFMLVSL-DEGPGPP------------------------IKYQYAELGK 2227
Query: 2517 MIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQH-------------------- 2556
+ ++V+ L+ + S L G P L Q
Sbjct: 2228 LYSVVSQLIRCCNVSSRMQSSINGNPPLPNPFGDPNLSQPIMPIQQNVADILFVRTSYVK 2287
Query: 2557 --IRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLM 2611
I D N +T L+ C N + + ++S L +A P+ LL ++
Sbjct: 2288 KIIEDCSNSEETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQIL 2344
Score = 67.8 bits (164), Expect = 2e-10
Identities = 80/321 (24%), Positives = 137/321 (42%), Gaps = 33/321 (10%)
Query: 159 LCVAKIFQIQFPLYTAYK------------HNTHPTIEDISTQESNILGAFCDMNDVEVP 206
LCVAK+ Q FPL + T P S+ + F D P
Sbjct: 158 LCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSSVQLPEDELFARSPDPRSP 217
Query: 207 LH-LLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHI 265
L+ + F NG ++ D F G+ L I A I +L + V ++
Sbjct: 218 KGWLVDLLNKFGTLNGFQILHDRFINGS--ALNVQIIAALIKPFGQCYEFLTLHTVKKYF 275
Query: 266 IPFRTYVIRYLCKLSDQELRQSA---ARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYF 322
+P V ++L L+D+EL++ A A+N A M + L + + +E++ +
Sbjct: 276 LPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFR 335
Query: 323 MSPTLTMRLAGLSQITNQLHTFNDVCNNESLVS----------DTETSIAKELADWLISN 372
+ + +RL +S +++ N+V S VS + E A+ +A+W+ N
Sbjct: 336 LK--MILRLLQISSFNGKMNALNEVNKVISSVSYYTHRHGNPEEEEWLTAERMAEWIQQN 393
Query: 373 NVVEHIFGPNLH-IEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH--CSRYIHDLF 429
N++ + +LH + +++ + IL F+ E L+ Q +D IWAA KH + +HDL
Sbjct: 394 NILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLL 453
Query: 430 PSLIKNLDPVPLRHLLNLVSA 450
L + P L HL + A
Sbjct: 454 AKLAWDFSPEQLDHLFDCFKA 474
Score = 59.3 bits (142), Expect = 7e-08
Identities = 75/329 (22%), Positives = 136/329 (41%), Gaps = 45/329 (13%)
Query: 862 LLWDIVQDEDA-VNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVI- 919
LLW++ +D V++ + ++ K+L D Q ++++I+ +E L N VI
Sbjct: 510 LLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQ-KIQWIDRFIEELRTNDKWVIP 568
Query: 920 ---SLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMK-------LFFDNLVYYIQTVR 969
+R + LFG Q S + +N ++ L +NL Y++++R
Sbjct: 569 ALKQIREICSLFGEAPQNLSQTQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMR 628
Query: 970 EGRQKH-----------ALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCL 1018
+ H + YSH EVQ RL FL + L Q +W CL
Sbjct: 629 LYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLL----KDGQLWLCAPQAKQIWKCL 684
Query: 1019 VEDSE--CYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHL 1076
E++ C +A + +++ D+ + + K F + QL P ++ G+ F+
Sbjct: 685 AENAVYLCDREACFKWYSKLMG-DEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERF 743
Query: 1077 -----CNLARLATS--AYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGK 1129
C +L AY + EL G+D W + +++ + D++ AI + Y N
Sbjct: 744 FKAVNCREGKLVAKRRAY-MMDDLELIGLDYLWRVVIQS-NDDIASRAIDLLKEIYTNLG 801
Query: 1130 TGLEKEQ-----EFISKCMESLMIASSSL 1153
L+ Q +FI C + L + +L
Sbjct: 802 PRLQVNQVVIHEDFIQSCFDRLKASYDTL 830
>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
Length = 2555
Score = 256 bits (655), Expect = 2e-67
Identities = 223/850 (26%), Positives = 371/850 (43%), Gaps = 130/850 (15%)
Query: 1733 EYFWLLCKLVD-----NIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGL 1787
+YF LL L++ NI+I +A + ++D L R IR + + + VE+ L
Sbjct: 1376 DYFTLLRHLLNYAYNGNINIPNAEVLLVSEIDWLKR-----IRDN-VKNTGETGVEEPIL 1429
Query: 1788 TGLLR-----LATSVVKHKPPFKFSREGQEFLRDIFNLLFLLPSLK-------------D 1829
G L LA + K F + G ++++ + F+ P+ K +
Sbjct: 1430 EGHLGVTKELLAFQTSEKKYHFGCEKGGANLIKELIDD-FIFPASKVYLQYLRSGELPAE 1488
Query: 1830 RQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQS------HAPYKWDYWP 1883
+ P C S + A ++LLV + G V N + I + + + A +W+Y P
Sbjct: 1489 QAIPVCSSPVTINAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLP 1548
Query: 1884 HEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAK----------------- 1926
R FVGL N GATCY+ S IQQLYMIP R ++ +
Sbjct: 1549 PVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQD 1608
Query: 1927 -------------------------YSEDMKHKT--TLLELQKMFTYLMESECKAYNPRP 1959
+ED K L LQ +F +L S+ + Y PR
Sbjct: 1609 SESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRG 1668
Query: 1960 FCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNT--VKSLFGGVITNNVVSLD 2017
F K + + +P+N EQ D EFF L+ ++E L + + + GG + +
Sbjct: 1669 FWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQG 1728
Query: 2018 CEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACF 2077
C H + E F T+ + + +N+ +SL++ D LEG N Y C C KKV KR
Sbjct: 1729 CPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLI 1788
Query: 2078 KKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYT--------EDFLMGKSER 2129
KKLPR+L+ R+ ++ K N +F FP LDM PYT D + ++E
Sbjct: 1789 KKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENEL 1848
Query: 2130 KEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDA 2189
E KE SD ++ + +Y L+GV VH+G A GGHYYS+I N + + WY F+D
Sbjct: 1849 IEQ-KEQSD-NETAGGTKYRLVGVLVHSGQASGGHYYSYIIQ-RNGKDDQTDHWYKFDDG 1905
Query: 2190 EV---KPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEEN- 2245
+V K D ++ ++CFGGE + +D + + ++ +AY+LFY++M+ +E+
Sbjct: 1906 DVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDD 1965
Query: 2246 -----------GREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSC----- 2289
R ++ +S + + N++F+ ++ + YF F+ +L +C
Sbjct: 1966 EMIRYISELTIARPHQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYL 2025
Query: 2290 --IPS---TLPDPKAVSLMTAKLSTSFVLETFIHSKE--KPTMLQWIELLTKQFNNSQAA 2342
P LP+ + +++++ +L+ F+ T H+K+ + W + L +S+
Sbjct: 2026 NPAPGQDYLLPEAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNV 2085
Query: 2343 CEWFLDR-MADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPG-MEDG 2400
WF + + + L++CP+ VR F +L + + AH LQ G
Sbjct: 2086 RFWFTHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFI--------AHFSLQDGSCPSP 2137
Query: 2401 SDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFL 2460
S + S +R L ++ V H HL +YF +A +G E L
Sbjct: 2138 FASPGPSSQACDNLSLSDHLLRATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQL 2197
Query: 2461 LSLQAISTMV 2470
L L +T +
Sbjct: 2198 LKLNVPATFM 2207
Score = 65.9 bits (159), Expect = 7e-10
Identities = 80/321 (24%), Positives = 137/321 (42%), Gaps = 33/321 (10%)
Query: 159 LCVAKIFQIQFPLYT--AYKHNTHPTIEDIS-TQESNILGA---------FCDMNDVEVP 206
LCVAK+ Q FPL A N H + T+ ++ + F +D P
Sbjct: 159 LCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSP 218
Query: 207 LH-LLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHI 265
L+ + F NG ++ D F G+ L I A I +L + ++
Sbjct: 219 KGWLVDLINKFGTLNGFQILHDRFFNGS--ALNIQIIAALIKPFGQCYEFLSQHTLKKYF 276
Query: 266 IPFRTYVIRYLCKLSDQELRQSA---ARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYF 322
IP V L L+D+EL++ A A+N A M + L + + E++ +
Sbjct: 277 IPVIEIVPHLLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFR 336
Query: 323 MSPTLTMRLAGLSQITNQLHTFNDVCNNESLVS----------DTETSIAKELADWLISN 372
+ + +RL +S +++ N++ S VS + E A+ +A+W+ N
Sbjct: 337 LK--MILRLLQISSFNGKMNALNEINKVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQN 394
Query: 373 NVVEHIFGPNLH-IEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH--CSRYIHDLF 429
N++ + +LH + +++ + IL F+ E L+ Q +D IWAA KH + +HDL
Sbjct: 395 NILSIVLQDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLL 454
Query: 430 PSLIKNLDPVPLRHLLNLVSA 450
L + P L HL + A
Sbjct: 455 AKLAWDFSPGQLDHLFDCFKA 475
Score = 60.5 bits (145), Expect = 3e-08
Identities = 74/328 (22%), Positives = 135/328 (41%), Gaps = 43/328 (13%)
Query: 862 LLWDIVQDEDA-VNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVI- 919
LLW++ Q +D V++ + ++ K+L D Q ++++I+ +E L N VI
Sbjct: 511 LLWNLAQSDDVPVDIMDLALSAHIKILDYSCSQDRDAQ-KIQWIDHFIEELRTNDKWVIP 569
Query: 920 ---SLRLLPKLFGTFQQFGSS-------YDTHWITMWAEKELNMMKLFFDNLVYYIQTVR 969
+R + LFG Q S + H + ++ ++ L +NL Y+ ++R
Sbjct: 570 ALKQIREICSLFGEASQNLSQTQRSPHIFYRHDLINQLQQNHALVTLVAENLATYMNSIR 629
Query: 970 EGRQKH-----------ALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCL 1018
H + YSH EVQ RL FL + L Q +W CL
Sbjct: 630 LYAGDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLL----KDGQLWLCAPQAKQIWKCL 685
Query: 1019 VEDSE--CYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHL 1076
E++ C +A + +++ D+ + + K F + QL P ++ G+ F+
Sbjct: 686 AENAVYLCDREACFKWYSKLMG-DEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERF 744
Query: 1077 -----CNLARLATSAYDGCSNS-ELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKT 1130
C +L + EL G+D W + +++ S +++ AI + Y N
Sbjct: 745 FKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVIQS-SDEIANRAIDLLKEIYTNLGP 803
Query: 1131 GLEKEQ-----EFISKCMESLMIASSSL 1153
L+ Q +FI C + L + +L
Sbjct: 804 RLKANQVVIHEDFIQSCFDRLKASYDTL 831
>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
Length = 2460
Score = 248 bits (634), Expect = 6e-65
Identities = 192/638 (30%), Positives = 289/638 (45%), Gaps = 43/638 (6%)
Query: 1639 CCSLVKSSLADSDHLQ---DWLKKLTLLIPETAVRHESCSGLYKLSLSGLDGGDSINRSF 1695
C L LA +L D++ + L P +R +C LY LS + + +
Sbjct: 1257 CLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPN 1316
Query: 1696 LLLAASTLLKFLPDAQALKPIRIDDYEEEPILKPGCKEYFWLLCKLVDNIHIKDASQTTL 1755
L L LP P I + +L C EYF L C+L+D++ + Q +
Sbjct: 1317 QFLLGVILTAQLP---LWSPTSIMRGVNQRLLSQ-CMEYFDLRCQLLDDLTTSEMEQLRI 1372
Query: 1756 LDLDALARHLA--DCIRSREILDHQDGNVEDDGLTGLLRLATSVVKHKPPFKFSREGQ-- 1811
L + D + + ++ L G LRL +++ K
Sbjct: 1373 SPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLI 1432
Query: 1812 -----EFL----RDIFNLLFLLPSLKDRQQ---PKCKSHSSRAAAYDLLVEMVKGSVENY 1859
+FL R I N S QQ PKC + +SR AAY++LV + S N
Sbjct: 1433 KPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNL 1492
Query: 1860 RLIHNWVMAQHMQSHAPY--KWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPE 1917
++I +++ H Q ++DY P D R+ FVGL N GATCY+ + QQLYM P
Sbjct: 1493 QIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPG 1552
Query: 1918 ARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQK 1977
+++ + D + ++Q +F +LMES+ + Y P F K + M + L EQ+
Sbjct: 1553 LPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQ 1612
Query: 1978 DMTEFFTDLITKIEEMSPEL--KNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQV 2035
D EFFT LI +++E ++ K+ F G+ ++ + DC H + E F + V
Sbjct: 1613 DAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGV 1672
Query: 2036 ADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNM 2095
+++ SLD+ + LEG N Y C C +K KR C K LP +L + MR+ F+
Sbjct: 1673 TSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDW 1732
Query: 2096 VTMMKEKVNTHFSFPLRLDMTPYTEDFLM---GKSERKEGFKEV------SDHSKDSESY 2146
+ K + FP L+M PYT + SE E + V S K + +
Sbjct: 1733 ESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTE 1792
Query: 2147 EYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFD--SAQLASECF 2204
Y+L+GV VH+G A GHYYSFI+D KWY FND ++ FD L ECF
Sbjct: 1793 NYELVGVIVHSGQAHAGHYYSFIKD---RRGCGKGKWYKFNDTVIEEFDLNDETLEYECF 1849
Query: 2205 GGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPE 2242
GGE K YD T+ + D + +AYMLFY+R+ +
Sbjct: 1850 GGEYRPKVYDQ-TNPYTDVR-RRYWNAYMLFYQRVSDQ 1885
Score = 80.5 bits (197), Expect = 3e-14
Identities = 161/753 (21%), Positives = 284/753 (37%), Gaps = 179/753 (23%)
Query: 841 QFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEA--EKLLCSLVCWFTDRQ 898
+FNS+ + + + + +K +LW++ L LI +A E L +
Sbjct: 391 KFNSDQLNHLFV--LIQKVLDVLWELAH---LPTLPSSLIQQALEEHLTILSDAYAVKEA 445
Query: 899 IRMRFIEGCLENLGNNRS--------VVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKE 950
I+ +I C+E++ + VV +LR L ++ +F + I +K
Sbjct: 446 IKRSYIIKCIEDIKRSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKN 505
Query: 951 LNMMKLFFDNLVYYIQ--------------TVREGRQKHALYSHSAEVQVRLQFLTCVFS 996
++KL +L+ + T+ +GR Y++ ++ L+FL
Sbjct: 506 FEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGR-----YTYREYLEAHLKFLAFFLQ 560
Query: 997 TLGSPDHFRLSLEQVDILWHCLVEDSE-CYDD---ALHWFLNQVRSKDQHAMGMETYKHL 1052
L + +W CLV + C D WF +K QH + + + L
Sbjct: 561 EAT----LYLGWNRAKEIWECLVTGQDVCELDREMCFEWF-----TKGQHDLESDVQQQL 611
Query: 1053 FLEKMPQLKPETISMTGLNLFQ------HLCNLARLATSAYDGCSNSELCGMDQFWGIAL 1106
F EK+ +L+ I+M G NLF+ +LC+ A EL GMD W IA+
Sbjct: 612 FKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAM 671
Query: 1107 RAQSGDVSRAAIQYINSY-YINGKTGLEKE-----QEFISKCMESLMIASSSL------- 1153
+ +++ AIQ I +Y YIN L+K+ ++FI+ C L ASS+L
Sbjct: 672 ESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTH 731
Query: 1154 ----------------------EQESHSSLMVIERGLLMLKTHLEAFRRRFAYHLRQWQI 1191
+ L++IER LL+ + ++ ++ R
Sbjct: 732 AVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVP-RTILP 790
Query: 1192 EGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKE 1251
G HL L L V + D T+E + ++ + +R W + K+
Sbjct: 791 HGASFHGHL--------LTLNVTYE--STKDTFTVEAHSNETIGSVR-----W--KIAKQ 833
Query: 1252 QINQQAQLQEFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVS 1311
+ +Q F ++ LT + D+K LH+LGF D Q++ V
Sbjct: 834 LCSPVDNIQIF--------------------TNDSLLTVNKDQKLLHQLGFSDEQILTVK 873
Query: 1312 L---GAPRRERKGEGVQ-------LPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLA 1361
G P + +S Q+ ++P +++ + +FD+L LA
Sbjct: 874 TSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMAL---VCNVFDMLYQLA 930
Query: 1362 SFKPPSGKVAVDDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISD----- 1416
+ + P ++ RV +LL+L+PT P + A +
Sbjct: 931 NLEEP----------------------RITLRVRKLLLLIPTDPAIQEALDQLDSLGRKK 968
Query: 1417 ---EQSNDGFNWKELLKIKSAHKLLYALEIIEAL------GKPNRRIRRESTGSYSDLYP 1467
+S+ + L K H+ A I+E+L G R+ S L P
Sbjct: 969 TLLSESSSQSSKSPSLSSKQQHQ-PSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMP 1027
Query: 1468 DSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEI 1500
+DD D + S+ F+ AGGL ++ +
Sbjct: 1028 TADD---DMARSCAKSFCENFLKAGGLSLVVNV 1057
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 145 bits (367), Expect = 5e-34
Identities = 116/408 (28%), Positives = 184/408 (45%), Gaps = 60/408 (14%)
Query: 1883 PHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTA-------------KYSE 1929
P+ + R + FVGLTNLGATCY+ + +Q ++ E RQA++ + +
Sbjct: 78 PNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEK 137
Query: 1930 DMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEF---FTDL 1986
D + +T LQ +F L S + +P F K +D TG+Q+D EF F L
Sbjct: 138 DYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLD-----TGQQQDAQEFSKLFMSL 192
Query: 1987 I--TKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYES 2044
+ T ++ +P+++N V+ F G V C S+ +FY + + K + +
Sbjct: 193 LEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDC 252
Query: 2045 LDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVN 2104
+ E ++ LEGDN Y C +C K A ++ LP L+ MR+ F+ T K+K+N
Sbjct: 253 ISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLN 312
Query: 2105 THFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGG 2163
T+ F LDM PY E K G SY Y+L V +H G +A G
Sbjct: 313 TYIGFSEILDMEPYV--------EHKGG------------SYVYELSAVLIHRGVSAYSG 352
Query: 2164 HYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQL---ASECFGGEMTTKTYDSVTDKF 2220
HY + ++D ++ +WY FND +++ + +L E ++T K
Sbjct: 353 HYIAHVKD------PQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKG 406
Query: 2221 MDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQF 2268
S +AYML Y+ E+ N V + L E + DN +F
Sbjct: 407 THCS----RNAYMLVYRLQTQEKPN---TTVQVPAFLQELVDRDNSKF 447
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 145 bits (367), Expect = 5e-34
Identities = 116/408 (28%), Positives = 184/408 (45%), Gaps = 60/408 (14%)
Query: 1883 PHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTA-------------KYSE 1929
P+ + R + FVGLTNLGATCY+ + +Q ++ E RQA++ + +
Sbjct: 78 PNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEK 137
Query: 1930 DMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEF---FTDL 1986
D + +T LQ +F L S + +P F K +D TG+Q+D EF F L
Sbjct: 138 DYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLD-----TGQQQDAQEFSKLFMSL 192
Query: 1987 I--TKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYES 2044
+ T ++ +P+++N V+ F G V C S+ +FY + + K + +
Sbjct: 193 LEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDC 252
Query: 2045 LDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVN 2104
+ E ++ LEGDN Y C +C K A ++ LP L+ MR+ F+ T K+K+N
Sbjct: 253 ISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLN 312
Query: 2105 THFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGG 2163
T+ F LDM PY E K G SY Y+L V +H G +A G
Sbjct: 313 TYIGFSEILDMEPYV--------EHKGG------------SYVYELSAVLIHRGVSAYSG 352
Query: 2164 HYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQL---ASECFGGEMTTKTYDSVTDKF 2220
HY + ++D ++ +WY FND +++ + +L E ++T K
Sbjct: 353 HYIAHVKD------PQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKG 406
Query: 2221 MDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQF 2268
S +AYML Y+ E+ N V + L E + DN +F
Sbjct: 407 THCS----RNAYMLVYRLQTQEKPN---TTVQVPAFLQELVDRDNSKF 447
>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
Length = 1287
Score = 132 bits (333), Expect = 5e-30
Identities = 101/401 (25%), Positives = 171/401 (42%), Gaps = 63/401 (15%)
Query: 1888 RAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLL--ELQKMFT 1945
++E +VGL N TCYL S +Q L+M PE R A++ ++ E + T + +LQ++F
Sbjct: 94 KSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFV 153
Query: 1946 YLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEM--SPELKNTVKS 2003
L S+ +A +++ D +Q D+ E + +E+ E + +
Sbjct: 154 LLQTSKKRAIETTDVTRSFGWDSS--EAWQQHDVQELCRVMFDALEQKWKQTEQADLINE 211
Query: 2004 LFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVAD------MKNIYESLDEVTIKDTLEGD 2057
L+ G + + V L+C + + + + + ++ E+L + L+G
Sbjct: 212 LYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGP 271
Query: 2058 NMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDM-- 2115
N Y C C KK A K F P +L+ R+ F+ TM + K+N +FP LDM
Sbjct: 272 NQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMST 331
Query: 2116 --------TPYTE--------------------DFLMGKS-------ERKEGFKEVSDHS 2140
+P TE DF E G +++S
Sbjct: 332 FIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSG 391
Query: 2141 KDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLA 2200
+ S Y+L V VH+G+A GGHYY+ I+ ++ + +WY FND V +
Sbjct: 392 LEKNSLIYELFSVMVHSGSAAGGHYYACIK------SFSDEQWYSFNDQHVSRITQEDI- 444
Query: 2201 SECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEP 2241
+ GG ++ Y S +F + +AYML Y+ +P
Sbjct: 445 KKTHGGSSGSRGYYS-------SAFASSTNAYMLIYRLKDP 478
>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
Length = 1102
Score = 123 bits (309), Expect = 3e-27
Identities = 103/372 (27%), Positives = 163/372 (43%), Gaps = 50/372 (13%)
Query: 1871 MQSHAPY--KWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYS 1928
+Q+ AP+ WD H +VGL N GATCY+ S +Q L+ + R+AV+
Sbjct: 195 VQADAPHGVAWDSKKHTG------YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTE 248
Query: 1929 EDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLIT 1988
D K+ L LQ++F L S+ K + K++ + L++ Q D+ E L+
Sbjct: 249 GDDSSKSVPLALQRVFYELQHSD-KPVGTKKLTKSFGW--ETLDSFMQHDVQELCRVLLD 305
Query: 1989 KIEEMSPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLD 2046
+E ++ T+ LF G + + + + ++ S E++Y ++ + KNI+ES
Sbjct: 306 NVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFV 365
Query: 2047 EVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTH 2106
+ + L+GDN Y G + AEK F LP +L MR+ ++ T K+N
Sbjct: 366 DYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDR 424
Query: 2107 FSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYY 2166
F FP +L + D + K++ K + Y L V VH+G GGHY
Sbjct: 425 FEFPEQLPL-----DEFLQKTDPK-------------DPANYILHAVLVHSGDNHGGHYV 466
Query: 2167 SFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFE 2226
++ NP + KW F+D + S C E Y D D S
Sbjct: 467 VYL----NPKG--DGKWCKFDD---------DVVSRCTKEEAIEHNYGGHDD---DLSVR 508
Query: 2227 KTHSAYMLFYKR 2238
+AYML Y R
Sbjct: 509 HCTNAYMLVYIR 520
>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
Length = 1247
Score = 123 bits (309), Expect = 3e-27
Identities = 78/291 (26%), Positives = 141/291 (48%), Gaps = 32/291 (10%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTA----------KYSEDMKHKTTLLELQKMF 1944
G+ N G TCYL S +Q L+ PE R+A+F+ K D K + L+LQ++F
Sbjct: 54 GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIPLQLQRLF 113
Query: 1945 TYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEE--MSPELKNTVK 2002
L+ + +A + ++ Q D+ E L + +E + + +
Sbjct: 114 AQLLLLDQEAASTADLTDSFGWTSN--EEMRQHDVQELNRILFSALETSLVGTSGHDLIY 171
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTL-EGDNMYT 2061
L+ G I N +V +C++VS+ E+F + V ++ + ++L + +++ + + DN+Y
Sbjct: 172 RLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSGLEDALWNMYVEEEVFDCDNLYH 231
Query: 2062 CSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTED 2121
C C + V+A K A +KLP L+ + +R+ F+ V + K + ++FPLR+++ P+ E
Sbjct: 232 CGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKPFCE- 290
Query: 2122 FLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDI 2172
D Y YDL V +H G GGHY+ +I+D+
Sbjct: 291 ----------------QSELDDLEYIYDLFSVIIHKGGCYGGHYHVYIKDV 325
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sapiens]
Length = 359
Score = 100 bits (248), Expect = 3e-20
Identities = 100/376 (26%), Positives = 152/376 (40%), Gaps = 71/376 (18%)
Query: 1893 FVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESEC 1952
+ GL N G TCY S +Q LY R+ V K ++ K + L L +F + +
Sbjct: 27 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYK-AQQKKKENLLTCLADLFHSIATQKK 85
Query: 1953 KA--YNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKI----------EEMSPELKNT 2000
K P+ F + + Q+D EF L+ I E+ + +LKN
Sbjct: 86 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 145
Query: 2001 ---------------VKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESL 2045
V +F G +TN L+CE VS E+F + V +I L
Sbjct: 146 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 205
Query: 2046 DEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNT 2105
+ + +TL + Y C C K A+KR KKLP IL+ + R+ + K++
Sbjct: 206 RDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSY 265
Query: 2106 HFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTA-DGGH 2164
FPL L + + D + + YDL+ V VH G+ + GH
Sbjct: 266 RVVFPLELRLFNTSSDAV-------------------NLDRMYDLVAVVVHCGSGPNRGH 306
Query: 2165 YYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFS 2224
Y + IV H + W LF+D V+ D AQ E +G +T+ D S
Sbjct: 307 YIT----IVKSHGF----WLLFDDDIVEKID-AQAIEEFYG--LTS-----------DIS 344
Query: 2225 FEKTHSAYMLFYKRME 2240
+ + S Y+LFY+ E
Sbjct: 345 -KNSESGYILFYQSRE 359
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapiens]
Length = 366
Score = 100 bits (248), Expect = 3e-20
Identities = 100/376 (26%), Positives = 152/376 (40%), Gaps = 71/376 (18%)
Query: 1893 FVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESEC 1952
+ GL N G TCY S +Q LY R+ V K ++ K + L L +F + +
Sbjct: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYK-AQQKKKENLLTCLADLFHSIATQKK 92
Query: 1953 KA--YNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKI----------EEMSPELKNT 2000
K P+ F + + Q+D EF L+ I E+ + +LKN
Sbjct: 93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152
Query: 2001 ---------------VKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESL 2045
V +F G +TN L+CE VS E+F + V +I L
Sbjct: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 212
Query: 2046 DEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNT 2105
+ + +TL + Y C C K A+KR KKLP IL+ + R+ + K++
Sbjct: 213 RDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSY 272
Query: 2106 HFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTA-DGGH 2164
FPL L + + D + + YDL+ V VH G+ + GH
Sbjct: 273 RVVFPLELRLFNTSSDAV-------------------NLDRMYDLVAVVVHCGSGPNRGH 313
Query: 2165 YYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFS 2224
Y + IV H + W LF+D V+ D AQ E +G +T+ D S
Sbjct: 314 YIT----IVKSHGF----WLLFDDDIVEKID-AQAIEEFYG--LTS-----------DIS 351
Query: 2225 FEKTHSAYMLFYKRME 2240
+ + S Y+LFY+ E
Sbjct: 352 -KNSESGYILFYQSRE 366
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 95.9 bits (237), Expect = 6e-19
Identities = 100/373 (26%), Positives = 147/373 (39%), Gaps = 71/373 (19%)
Query: 1893 FVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESEC 1952
+ GL N G TCY S +Q LY R+ V K S+ K ++ L L +F + +
Sbjct: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYK-SQPRKKESLLTCLADLFHSIATQKK 96
Query: 1953 KA--YNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKI-----EEMSPELKNT----- 2000
K P+ F + + + Q+D EF L+ I EE E +N
Sbjct: 97 KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156
Query: 2001 ---------------VKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESL 2045
V +F G +TN L CE +S E+F + V +I L
Sbjct: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCL 216
Query: 2046 DEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNT 2105
+ +TL + Y C C K A KR KKLP IL+ + R+ + K++
Sbjct: 217 RGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSY 276
Query: 2106 HFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTA-DGGH 2164
FPL L + F D + YDL+ V VH G+ + GH
Sbjct: 277 RVVFPLELRL-----------------FNTSGDATNPDRM--YDLVAVVVHCGSGPNRGH 317
Query: 2165 YYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFS 2224
Y + IV H + W LF+D V+ D AQ E +G +T+ D S
Sbjct: 318 YIA----IVKSHDF----WLLFDDDIVEKID-AQAIEEFYG--LTS-----------DIS 355
Query: 2225 FEKTHSAYMLFYK 2237
+ + S Y+LFY+
Sbjct: 356 -KNSESGYILFYQ 367
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 94.7 bits (234), Expect = 1e-18
Identities = 74/311 (23%), Positives = 126/311 (40%), Gaps = 45/311 (14%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKA 1954
GL NLG TC+L +TIQ L P + + +++ H+ + L M +++++ +
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSC-HQGSFCMLCVMQNHIVQAFANS 181
Query: 1955 YN---PRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIE----------EMSPELKNTV 2001
N P F + + G Q+D EF I ++ + + V
Sbjct: 182 GNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQATTLV 241
Query: 2002 KSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYT 2061
+FGG + + V C+ VS T + + V ++ NI +L+ D L G+N Y
Sbjct: 242 HQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALELFVKADVLSGENAYM 301
Query: 2062 CSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTED 2121
C+ C KKV A KR + +L+ + R+ K+ +P L++ PY
Sbjct: 302 CAKCKKKVPASKRFTIHRTSNVLTLSLKRF----ANFSGGKITKDVGYPEFLNIRPYMS- 356
Query: 2122 FLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKN 2180
+ + Y L V VH+G + GHYY +++ N
Sbjct: 357 ------------------QNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVK-------ASN 391
Query: 2181 NKWYLFNDAEV 2191
+WY ND+ V
Sbjct: 392 GQWYQMNDSLV 402
>gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
Length = 372
Score = 90.1 bits (222), Expect = 3e-17
Identities = 85/383 (22%), Positives = 154/383 (40%), Gaps = 56/383 (14%)
Query: 1867 MAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAV--FT 1924
M + P WDY PH VGL N+G TC L S IQ M + + + T
Sbjct: 36 MKREQPRERPRAWDY-PHG-------LVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT 87
Query: 1925 AKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFT 1984
D + ++ ++ + + +S KA RP Y + K + Q D + +
Sbjct: 88 VPRGADEQRRSVPFQMLLLLEKMQDSRQKAV--RPLELAYCLQKCNVPLFVQHDAAQLYL 145
Query: 1985 DLITKIEEMSPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVAD----- 2037
L I++ + L +++L+ + ++++ +DC S T+ + D
Sbjct: 146 KLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKP 205
Query: 2038 MKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVT 2097
+K + ++L L + C +CGKK R ++ LP+ L+ + MR F++
Sbjct: 206 LKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMR--FSIRN 263
Query: 2098 MMKEKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHT 2157
K+ FP LD + K S +++ +Y+L V H
Sbjct: 264 SQTRKICHSLYFPQSLDFSQILP------------MKRESCDAEEQSGGQYELFAVIAHV 311
Query: 2158 GTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVT 2217
G AD GHY +IR+ V + KW+ FND+ + +++ +
Sbjct: 312 GMADSGHYCVYIRNAV------DGKWFCFNDSNI-----------------CLVSWEDIQ 348
Query: 2218 DKFMDFSFEKTHSAYMLFYKRME 2240
+ + ++ +AY+L Y +ME
Sbjct: 349 CTYGNPNYHWQETAYLLVYMKME 371
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 87.8 bits (216), Expect = 2e-16
Identities = 70/321 (21%), Positives = 125/321 (38%), Gaps = 43/321 (13%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHK--TTLLELQKMFTYLMESEC 1952
GL NLG TC+ + +Q L P + + ++S+ + + +Q T + +
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQAHITQALSNPG 171
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIE----------EMSPELKNTVK 2002
P + G Q+D EF + ++ + + V
Sbjct: 172 DVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVC 231
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + V L+C+ VS T + + + ++ +++ ++L++ + L+G+N Y C
Sbjct: 232 QIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKC 291
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
S C K V A KR + +L+ + R+ K+ +P LD+ PY
Sbjct: 292 SKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYPEYLDIRPYMS-- 345
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
+ E Y L V VHTG GHY+ +I+ N
Sbjct: 346 -----------------QPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIK-------ASNG 381
Query: 2182 KWYLFNDAEVKPFDSAQLASE 2202
WY ND+ V D + S+
Sbjct: 382 LWYQMNDSIVSTSDIRSVLSQ 402
>gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 346
Score = 86.3 bits (212), Expect = 5e-16
Identities = 77/325 (23%), Positives = 132/325 (40%), Gaps = 39/325 (12%)
Query: 1876 PYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAV--FTAKYSEDMKH 1933
P WDY VGL N+G TC L S IQ M + + + T D +
Sbjct: 34 PRSWDY--------RHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQR 85
Query: 1934 KTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEM 1993
++ ++ + + +S KA P Y + K + Q D + + L I++
Sbjct: 86 RSVPFQMLLLLEKMQDSRQKAVWPLELA--YCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 143
Query: 1994 SPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVAD-----MKNIYESLD 2046
+ L +++L+ + ++++ LDC S T+R D +K + ++L
Sbjct: 144 IADVHLVERLQALYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 203
Query: 2047 EVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTH 2106
L + C +CGKK R ++ LP+ L+ + MR F++ K+
Sbjct: 204 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMR--FSIRNSQTRKICHS 261
Query: 2107 FSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYY 2166
FP LD + K S +++ +Y+L V H G AD GHY
Sbjct: 262 LYFPQSLDFSQILP------------MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYC 309
Query: 2167 SFIRDIVNPHAYKNNKWYLFNDAEV 2191
+IR+ V + KW+ FND+ +
Sbjct: 310 VYIRNAV------DGKWFCFNDSNI 328
>gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sapiens]
Length = 347
Score = 86.3 bits (212), Expect = 5e-16
Identities = 77/325 (23%), Positives = 132/325 (40%), Gaps = 39/325 (12%)
Query: 1876 PYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAV--FTAKYSEDMKH 1933
P WDY VGL N+G TC L S IQ M + + + T D +
Sbjct: 34 PRSWDY--------RHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQR 85
Query: 1934 KTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEM 1993
++ ++ + + +S KA P Y + K + Q D + + L I++
Sbjct: 86 RSVPFQMLLLLEKMQDSRQKAVWPLELA--YCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 143
Query: 1994 SPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVAD-----MKNIYESLD 2046
+ L +++L+ + ++++ LDC S T+R D +K + ++L
Sbjct: 144 IADVHLVERLQALYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 203
Query: 2047 EVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTH 2106
L + C +CGKK R ++ LP+ L+ + MR F++ K+
Sbjct: 204 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMR--FSIRNSQTRKICHS 261
Query: 2107 FSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYY 2166
FP LD + K S +++ +Y+L V H G AD GHY
Sbjct: 262 LYFPQSLDFSQILP------------MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYC 309
Query: 2167 SFIRDIVNPHAYKNNKWYLFNDAEV 2191
+IR+ V + KW+ FND+ +
Sbjct: 310 VYIRNAV------DGKWFCFNDSNI 328
>gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 344
Score = 84.7 bits (208), Expect = 1e-15
Identities = 73/307 (23%), Positives = 127/307 (41%), Gaps = 31/307 (10%)
Query: 1894 VGLTNLGATCYLASTIQQLYMIPEARQAV--FTAKYSEDMKHKTTLLELQKMFTYLMESE 1951
VGL N+G TC L S IQ M + + + T D + ++ ++ + + +S
Sbjct: 21 VGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQDSR 80
Query: 1952 CKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPE--LKNTVKSLFGGVI 2009
KA P Y + K + Q D + + L I++ + L +++L+ +
Sbjct: 81 QKAVWPLELA--YCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQALYMIRV 138
Query: 2010 TNNVVSLDCEHVSQTAEEFYTVRCQVAD-----MKNIYESLDEVTIKDTLEGDNMYTCSH 2064
++++ LDC S T+R D +K + ++L L + C +
Sbjct: 139 KDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCEN 198
Query: 2065 CGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLM 2124
CGKK R ++ LP+ L+ + MR F++ K+ FP LD +
Sbjct: 199 CGKKTRGKQVLKLTHLPQTLTIHLMR--FSIRNSQTRKICHSLYFPQSLDFSQILP---- 252
Query: 2125 GKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWY 2184
K S +++ +Y+L V H G AD GHY +IR V + KW+
Sbjct: 253 --------MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAV------DGKWF 298
Query: 2185 LFNDAEV 2191
FND+ +
Sbjct: 299 CFNDSNI 305
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 84.7 bits (208), Expect = 1e-15
Identities = 78/337 (23%), Positives = 130/337 (38%), Gaps = 58/337 (17%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLL--ELQKMFTYLMESEC 1952
GL NLG TC++ +Q L P R + ++ +M+ ++ L E+ +F
Sbjct: 177 GLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHR 236
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNT------------ 2000
+ P + L EQ+D EF LI ++ + K
Sbjct: 237 SPHIPYKLLHLVWTHARHLAGYEQQDAHEF---LIAALDVLHRHCKGDDNGKKANNPNHC 293
Query: 2001 ---VKSLFGGVITNNVVSLDCEHVSQTAEEFYTV-------------------------R 2032
+ +F G + ++V C VS T + F+ +
Sbjct: 294 NCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGE 353
Query: 2033 CQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYT 2092
V+ + + L T + L CS C + K+ KKLP + F+ R+
Sbjct: 354 SHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFE 413
Query: 2093 FNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIG 2152
+ ++ K+ T+ SFPL LDMTP+ K R G + S ++++ +Y L
Sbjct: 414 HS--AKLRRKITTYVSFPLELDMTPF---MASSKESRMNGQYQQPTDSLNNDN-KYSLFA 467
Query: 2153 VTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDA 2189
V H GT + GHY SFIR ++W+ +DA
Sbjct: 468 VVNHQGTLESGHYTSFIRQ-------HKDQWFKCDDA 497
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 84.3 bits (207), Expect = 2e-15
Identities = 91/390 (23%), Positives = 150/390 (38%), Gaps = 99/390 (25%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKH----KTTLLE--LQKMFTYLM 1948
GL NLG TC++ S +Q L E R Y D+ H T L+E + + T
Sbjct: 59 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 118
Query: 1949 ESECKAYNPRPFCKTYTMDKQPLNTG-EQKDMTEFFTDL----------ITKIEEMSPEL 1997
S +P F KT P G Q+D EF L +T + +PE
Sbjct: 119 SSPNDVVSPSEF-KTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 177
Query: 1998 ---------------------KNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVA 2036
+ + LF G + +++ DC + S + F+ + +A
Sbjct: 178 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 237
Query: 2037 DMK----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYT 2092
+ + + T +D L+GD TC C + R K+ ++ P+IL + R++
Sbjct: 238 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 297
Query: 2093 FNMVTMMKEKVNTHFSFPLR-LDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLI 2151
+ + K+ T +FPLR LD+ + S+++ Y+L
Sbjct: 298 ESRI--RTSKLTTFVNFPLRDLDLREFA--------------------SENTNHAVYNLY 335
Query: 2152 GVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTK 2211
V+ H+GT GGHY ++ R + +W+ FND+ V P S+Q+
Sbjct: 336 AVSNHSGTTMGGHYTAYCR------SPGTGEWHTFNDSSVTPMSSSQV------------ 377
Query: 2212 TYDSVTDKFMDFSFEKTHSAYMLFYKRMEP 2241
+T AY+LFY+ P
Sbjct: 378 ---------------RTSDAYLLFYELASP 392
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapiens]
Length = 605
Score = 84.3 bits (207), Expect = 2e-15
Identities = 91/390 (23%), Positives = 150/390 (38%), Gaps = 99/390 (25%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKH----KTTLLE--LQKMFTYLM 1948
GL NLG TC++ S +Q L E R Y D+ H T L+E + + T
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 1949 ESECKAYNPRPFCKTYTMDKQPLNTG-EQKDMTEFFTDL----------ITKIEEMSPEL 1997
S +P F KT P G Q+D EF L +T + +PE
Sbjct: 328 SSPNDVVSPSEF-KTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
Query: 1998 ---------------------KNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVA 2036
+ + LF G + +++ DC + S + F+ + +A
Sbjct: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
Query: 2037 DMK----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYT 2092
+ + + T +D L+GD TC C + R K+ ++ P+IL + R++
Sbjct: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
Query: 2093 FNMVTMMKEKVNTHFSFPLR-LDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLI 2151
+ + K+ T +FPLR LD+ + S+++ Y+L
Sbjct: 507 ESRI--RTSKLTTFVNFPLRDLDLREFA--------------------SENTNHAVYNLY 544
Query: 2152 GVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTK 2211
V+ H+GT GGHY ++ R + +W+ FND+ V P S+Q+
Sbjct: 545 AVSNHSGTTMGGHYTAYCR------SPGTGEWHTFNDSSVTPMSSSQV------------ 586
Query: 2212 TYDSVTDKFMDFSFEKTHSAYMLFYKRMEP 2241
+T AY+LFY+ P
Sbjct: 587 ---------------RTSDAYLLFYELASP 601
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 84.0 bits (206), Expect = 2e-15
Identities = 82/334 (24%), Positives = 130/334 (38%), Gaps = 53/334 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLL--ELQKMFTYLMESEC 1952
GL NLG TC++ +Q L IP + + K+ M + L E+ +F +
Sbjct: 364 GLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSLCLVCEMSSLFHAMYSGSR 423
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKI-----------EEMSPELKNTV 2001
+ P + + L Q+D EF ++ + E +P N +
Sbjct: 424 TPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSKDDSGGQEANNPNCCNCI 483
Query: 2002 -KSLFGGVITNNVVSLDCEHVSQTAEEFYTVR------CQVADMKNIYESLDEVTIKDTL 2054
+F G + ++V C VS T + + + C D +N + V+ D +
Sbjct: 484 IDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDDHI 543
Query: 2055 EGDNMYT-------------------CSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNM 2095
G T C+ C + K+ KKLP + F+ R F
Sbjct: 544 PGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKR--FEH 601
Query: 2096 VTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTV 2155
V + K+NT SFPL LDMTP+ +S KEG ++ +Y L V
Sbjct: 602 VGKQRRKINTFISFPLELDMTPFLAS--TKESRMKEGQPPTDCVPNEN---KYSLFAVIN 656
Query: 2156 HTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDA 2189
H GT + GHY SFIR + ++W+ +DA
Sbjct: 657 HHGTLESGHYTSFIRQ-------QKDQWFSCDDA 683
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 80.9 bits (198), Expect = 2e-14
Identities = 74/335 (22%), Positives = 125/335 (37%), Gaps = 51/335 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLL--ELQKMFTYLMESEC 1952
GL NLG TC++ +Q L P R + ++ +M L E+ +F L
Sbjct: 79 GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSSLFRELYSGNP 138
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFT------------DLITKIEEMSPELKNT 2000
+ P + + L Q+D EF D + K
Sbjct: 139 SPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNHCNCI 198
Query: 2001 VKSLFGGVITNNVVSLDCEHVSQTAEEFYTV------------------------RCQVA 2036
+ +F G + ++V C VS T + + + +
Sbjct: 199 IDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIP 258
Query: 2037 DMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMV 2096
+ + + L T + L C C + K+ KLP + F+ R+ +
Sbjct: 259 GITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHS-- 316
Query: 2097 TMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVH 2156
+ K+ T+ SFPL LDMTP+ K R G ++ +S ++E+ +Y L V H
Sbjct: 317 AKQRRKITTYISFPLELDMTPFMAS---SKESRMNGQLQLPTNSGNNEN-KYSLFAVVNH 372
Query: 2157 TGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEV 2191
GT + GHY SFIR + ++W+ +DA +
Sbjct: 373 QGTLESGHYTSFIR-------HHKDQWFKCDDAVI 400
>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 4e-14
Identities = 68/310 (21%), Positives = 132/310 (42%), Gaps = 49/310 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM-KHKTTLL-ELQKMFTYLMESEC 1952
GL N+G TCY+ +++Q L P + + ++S+ +HK +L +Q T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRAL---- 136
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFF---TDLITKI-----EEMSPELKNT--VK 2002
+NP + + G+Q+D EF D + K +++ K+T +
Sbjct: 137 --HNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIH 194
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + L C +S T + + + + +++ ++L+++ + L G+N Y C
Sbjct: 195 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHC 254
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
C ++ A K ++L R++ + K+ + +P LDM PY
Sbjct: 255 GVCLQRAPASKTLTLHTSAKVLILVLKRFS----DVTGNKIAKNVQYPECLDMQPYMS-- 308
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
+++ Y L V VH G + GHY+S+++ +
Sbjct: 309 -----------------QQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK-------AQEG 344
Query: 2182 KWYLFNDAEV 2191
+WY +DAEV
Sbjct: 345 QWYKMDDAEV 354
>gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 4e-14
Identities = 68/310 (21%), Positives = 132/310 (42%), Gaps = 49/310 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM-KHKTTLL-ELQKMFTYLMESEC 1952
GL N+G TCY+ +++Q L P + + ++S+ +HK +L +Q T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRAL---- 136
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFF---TDLITKI-----EEMSPELKNT--VK 2002
+NP + + G+Q+D EF D + K +++ K+T +
Sbjct: 137 --HNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIH 194
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + L C +S T + + + + +++ ++L+++ + L G+N Y C
Sbjct: 195 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHC 254
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
C ++ A K ++L R++ + K+ + +P LDM PY
Sbjct: 255 GVCLQRAPASKTLTLHTSAKVLILVLKRFS----DVTGNKIAKNVQYPECLDMQPYMS-- 308
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
+++ Y L V VH G + GHY+S+++ +
Sbjct: 309 -----------------QQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK-------AQEG 344
Query: 2182 KWYLFNDAEV 2191
+WY +DAEV
Sbjct: 345 QWYKMDDAEV 354
>gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 4e-14
Identities = 68/310 (21%), Positives = 132/310 (42%), Gaps = 49/310 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM-KHKTTLL-ELQKMFTYLMESEC 1952
GL N+G TCY+ +++Q L P + + ++S+ +HK +L +Q T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRAL---- 136
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFF---TDLITKI-----EEMSPELKNT--VK 2002
+NP + + G+Q+D EF D + K +++ K+T +
Sbjct: 137 --HNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIH 194
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + L C +S T + + + + +++ ++L+++ + L G+N Y C
Sbjct: 195 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHC 254
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
C ++ A K ++L R++ + K+ + +P LDM PY
Sbjct: 255 GVCLQRAPASKTLTLHTSAKVLILVLKRFS----DVTGNKIAKNVQYPECLDMQPYMS-- 308
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
+++ Y L V VH G + GHY+S+++ +
Sbjct: 309 -----------------QQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK-------AQEG 344
Query: 2182 KWYLFNDAEV 2191
+WY +DAEV
Sbjct: 345 QWYKMDDAEV 354
>gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo
sapiens]
Length = 530
Score = 79.7 bits (195), Expect = 5e-14
Identities = 69/310 (22%), Positives = 130/310 (41%), Gaps = 49/310 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM-KHKTTLL-ELQKMFTYLMESEC 1952
GL N+G TCY+ +++Q L P + + ++S+ +HK +L +Q T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRAL---- 136
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFF---TDLITKI-----EEMSPELKNT--VK 2002
+NP + + G+Q+D EF D + K +++ K+T +
Sbjct: 137 --HNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIH 194
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + L C +S T + + + + +++ ++L+++ + L G+N Y C
Sbjct: 195 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHC 254
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
C ++ A K ++L R++ + K+ + +P LDM PY
Sbjct: 255 GVCLQRAPASKTLTLHTSAKVLILVLKRFS----DVTGNKIAKNVQYPECLDMQPYMSQT 310
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
G Y L V VH G + GHY+S+++ +
Sbjct: 311 NTG-------------------PLVYVLYAVLVHAGWSCHNGHYFSYVK-------AQEG 344
Query: 2182 KWYLFNDAEV 2191
+WY +DAEV
Sbjct: 345 QWYKMDDAEV 354
>gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo
sapiens]
Length = 530
Score = 79.7 bits (195), Expect = 5e-14
Identities = 69/310 (22%), Positives = 130/310 (41%), Gaps = 49/310 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM-KHKTTLL-ELQKMFTYLMESEC 1952
GL N+G TCY+ +++Q L P + + ++S+ +HK +L +Q T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRAL---- 136
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFF---TDLITKI-----EEMSPELKNT--VK 2002
+NP + + G+Q+D EF D + K +++ K+T +
Sbjct: 137 --HNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIH 194
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + L C +S T + + + + +++ ++L+++ + L G+N Y C
Sbjct: 195 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHC 254
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
C ++ A K ++L R++ + K+ + +P LDM PY
Sbjct: 255 GVCLQRAPASKTLTLHTSAKVLILVLKRFS----DVTGNKIAKNVQYPECLDMQPYMSQT 310
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
G Y L V VH G + GHY+S+++ +
Sbjct: 311 NTG-------------------PLVYVLYAVLVHAGWSCHNGHYFSYVK-------AQEG 344
Query: 2182 KWYLFNDAEV 2191
+WY +DAEV
Sbjct: 345 QWYKMDDAEV 354
>gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo
sapiens]
Length = 530
Score = 79.7 bits (195), Expect = 5e-14
Identities = 68/310 (21%), Positives = 132/310 (42%), Gaps = 49/310 (15%)
Query: 1895 GLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM-KHKTTLL-ELQKMFTYLMESEC 1952
GL N+G TCY+ +++Q L P + + ++S+ +HK +L +Q T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRAL---- 136
Query: 1953 KAYNPRPFCKTYTMDKQPLNTGEQKDMTEFF---TDLITKI-----EEMSPELKNT--VK 2002
+NP + + G+Q+D EF D + K +++ K+T +
Sbjct: 137 --HNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHPSKDTTLIH 194
Query: 2003 SLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTC 2062
+FGG + + L C +S T + + + + +++ ++L+++ + L G+N Y C
Sbjct: 195 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHC 254
Query: 2063 SHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDF 2122
C ++ A K ++L R++ + K+ + +P LDM PY
Sbjct: 255 GVCLQRAPASKTLTLHTSAKVLILVLKRFS----DVTGNKIAKNVQYPECLDMQPYMS-- 308
Query: 2123 LMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTG-TADGGHYYSFIRDIVNPHAYKNN 2181
+++ Y L V VH G + GHY+S+++ +
Sbjct: 309 -----------------QQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK-------AQEG 344
Query: 2182 KWYLFNDAEV 2191
+WY +DAEV
Sbjct: 345 QWYKMDDAEV 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 137,120,299
Number of Sequences: 37866
Number of extensions: 6275014
Number of successful extensions: 34945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 30255
Number of HSP's gapped (non-prelim): 3377
length of query: 3546
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3424
effective length of database: 13,627,866
effective search space: 46661813184
effective search space used: 46661813184
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.