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Search of human proteins with 149944680
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944680 HAUS augmin-like complex, subunit 5 [Homo sapiens]
(633 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149944680 HAUS augmin-like complex, subunit 5 [Homo sapiens] 1251 0.0
gi|21735548 centrosomal protein 2 [Homo sapiens] 52 1e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 49 1e-05
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 48 2e-05
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 48 2e-05
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 48 2e-05
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 45 2e-04
gi|167555110 kinesin family member C1 [Homo sapiens] 44 3e-04
gi|117956403 rabaptin, RAB GTPase binding effector protein 2 [Ho... 43 0.001
gi|148746195 trichohyalin [Homo sapiens] 42 0.001
gi|16262452 cingulin [Homo sapiens] 42 0.002
gi|4758650 kinesin family member 5C [Homo sapiens] 41 0.003
gi|116008447 CAP-GLY domain containing linker protein 2 isoform ... 41 0.003
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 41 0.003
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 41 0.004
gi|53729363 leucine rich repeat and sterile alpha motif containi... 41 0.004
gi|53729361 leucine rich repeat and sterile alpha motif containi... 41 0.004
gi|53729359 leucine rich repeat and sterile alpha motif containi... 41 0.004
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 40 0.005
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 40 0.005
gi|45439327 periplakin [Homo sapiens] 40 0.005
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 40 0.005
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 40 0.007
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 40 0.007
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 40 0.009
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 40 0.009
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 40 0.009
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 40 0.009
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 39 0.011
gi|154813191 IQ motif containing E isoform 1 [Homo sapiens] 39 0.011
>gi|149944680 HAUS augmin-like complex, subunit 5 [Homo sapiens]
Length = 633
Score = 1251 bits (3238), Expect = 0.0
Identities = 633/633 (100%), Positives = 633/633 (100%)
Query: 1 MELAQEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIR 60
MELAQEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIR
Sbjct: 1 MELAQEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIR 60
Query: 61 GNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQ 120
GNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQ
Sbjct: 61 GNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQ 120
Query: 121 DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL 180
DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL
Sbjct: 121 DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL 180
Query: 181 EPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPP 240
EPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPP
Sbjct: 181 EPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPP 240
Query: 241 GHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRT 300
GHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRT
Sbjct: 241 GHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRT 300
Query: 301 VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD 360
VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD
Sbjct: 301 VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD 360
Query: 361 QSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGE 420
QSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGE
Sbjct: 361 QSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGE 420
Query: 421 VLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSI 480
VLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSI
Sbjct: 421 VLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSI 480
Query: 481 HQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMK 540
HQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMK
Sbjct: 481 HQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMK 540
Query: 541 TSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPG 600
TSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPG
Sbjct: 541 TSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPG 600
Query: 601 QAALSEELCQGLSLPQWRLRWVQAQGALQKLCS 633
QAALSEELCQGLSLPQWRLRWVQAQGALQKLCS
Sbjct: 601 QAALSEELCQGLSLPQWRLRWVQAQGALQKLCS 633
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 52.4 bits (124), Expect = 1e-06
Identities = 134/609 (22%), Positives = 234/609 (38%), Gaps = 62/609 (10%)
Query: 47 LQHVHSQRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTE 106
LQ SQ +K + W G Q+S + +EL + L++ ++ + + + E
Sbjct: 1290 LQRQLSQNQEEKSK----WEGKQNSLE-SELMELHETMASLQSRLRRAELQRMEAQGERE 1344
Query: 107 AQDTAMEQARQHTQDTQRRALLLRAQAGA-------MRRQQHTLRDPMQRLQNQLRRLQD 159
A E + Q + RAQA A +R + L+ + ++++ R Q
Sbjct: 1345 LLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQA 1404
Query: 160 MERKAKVDVTFGSLTSAALGLEPVVLRDVRTAC-TLRAQFLQNLLLPQAKRG-----SLP 213
++ + ++ V G L L L + TLR Q + + ++ SL
Sbjct: 1405 LQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLD 1464
Query: 214 TPHDDHFGTSYQQWLSSVETL--LTNHPPGHVLAALEHLAAEREAEIRSLCSGDGLGDTE 271
+ Q+ + +E + H P V + L +RE +IR L D
Sbjct: 1465 LKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQRE-QIREL-EKDRETQRN 1522
Query: 272 ISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVER 331
+ Q + Q + S +Q+ + + V + + L+E + Q L++E+E
Sbjct: 1523 VLEHQLLELEKKDQMIESQRGQVQDLKKQL-VTLECLALELEENHHKMECQQKLIKELE- 1580
Query: 332 RVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQ 391
G E Q + L L + L QS ++ D H +L RELQ + Q + R+
Sbjct: 1581 ---GQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE 1637
Query: 392 LVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEV 451
+EE Q Q L + L R E++ +R + + Q + LEE++
Sbjct: 1638 QIEELQRQKEHLTQD-------LERRDQELMLQKER-----IQVLEDQRTRQTKILEEDL 1685
Query: 452 RHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHPASPRGSSFI---ALSHKLGLPPGKAS 508
+ LR R EL T + Q +G S +L H + K
Sbjct: 1686 EQIK-----LSLRERGREL----TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEK 1736
Query: 509 ELLLPAAASLRQDLLLLQDQRSLWCWDLLHMK---TSLPPGLPTQEL--LQIQASQEKQQ 563
E + +L L+DQ LH K TSL QE+ LQ Q + ++Q
Sbjct: 1737 E--VECQQEHIHELQELKDQLEQQLQG-LHRKVGETSLLLSQREQEIVVLQQQLQEAREQ 1793
Query: 564 KENLGQALK-RLEKLLKQALERIPELQGIVGDWWEQPGQAALSEELCQGL--SLPQWRLR 620
E Q+L+ +L++ + +R EL+ + + + GQ +E L +L Q +
Sbjct: 1794 GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMT 1853
Query: 621 WVQAQGALQ 629
+ G LQ
Sbjct: 1854 LKERHGELQ 1862
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/372 (21%), Positives = 150/372 (40%), Gaps = 47/372 (12%)
Query: 80 LEAAVTRLRAEIQELDQSL-------ELMERDTEAQDTAMEQARQHTQD-TQRRALL--- 128
+ + +TR R +Q+L Q L L+++ + + + RQ Q T R L
Sbjct: 391 VRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQ 450
Query: 129 ---LRAQAGAMRRQQHTLRDPMQRLQNQLRRL-QDMERKAKVDVTFGSLTSAALGLEPVV 184
L+ + ++ +++ L+ + L+ QL L Q+ R +V+V +A G +
Sbjct: 451 TVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQ 510
Query: 185 LRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVL 244
++ A R + + L+ +AK+ S + ++ E L ++H G +L
Sbjct: 511 QEELHLAVRERERLQEMLMGLEAKQSE-----------SLSELITLREALESSHLEGELL 559
Query: 245 ----AALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRT 300
+ A E I L S + TE++ +A S+ L + L + G
Sbjct: 560 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSA--LNEALALDKVG--- 614
Query: 301 VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD 360
L Q L +E Q + R++ + + +E + RR LW + L
Sbjct: 615 ---LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAE-----KRREALWEKNTHLEA 666
Query: 361 QSQELQDAAGHRQLLLRELQAK----QQRILHWRQLVEETQEQVRLLIKGNSASKTRLCR 416
Q Q+ ++A Q LR++Q + Q+++ R E Q+ L + + L R
Sbjct: 667 QLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLAR 726
Query: 417 SPGEVLALVQRK 428
+ E ALV+ K
Sbjct: 727 AVQEKEALVREK 738
Score = 38.9 bits (89), Expect = 0.015
Identities = 75/313 (23%), Positives = 130/313 (41%), Gaps = 45/313 (14%)
Query: 315 RQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQL 374
R VLT+R Q V+++ +++ G E V +L + E KAL Q LQ G R
Sbjct: 392 RSVLTRRRQA-VQDLRQQLAGCQEA-VNLLQQQHDQWEEEGKALR---QRLQKLTGERDT 446
Query: 375 LLRE---LQAKQQRILHWRQLVEETQEQVR-------------------LLIKGNSASKT 412
L + LQ + + R+L+++ +E++R L ++G+SA
Sbjct: 447 LAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQ 506
Query: 413 RLCRSPGEVLALVQRK----VVPTFEAVAPQSRELLRCLEE--EVRHLPHILLGTLLRHR 466
+ + LA+ +R+ ++ EA +S L L E E HL G LLR
Sbjct: 507 KEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLE----GELLRQE 562
Query: 467 PGELKP-LPTVLPSIHQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLL 525
E+ L SI +L + + +A + +E L L Q LL L
Sbjct: 563 QTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQL 622
Query: 526 QDQRSLWCWDLLHMKTSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERI 585
+++ C + + + LQ+ ++ ++++E L + LE L++A E
Sbjct: 623 EEENQSVC-------SRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAG 675
Query: 586 PELQGIVGDWWEQ 598
ELQ + D E+
Sbjct: 676 AELQADLRDIQEE 688
Score = 35.8 bits (81), Expect = 0.12
Identities = 76/395 (19%), Positives = 150/395 (37%), Gaps = 81/395 (20%)
Query: 53 QRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAM 112
Q+ V+ ++ L+ DS ++ +E V E QE ++ + +ER+ + ++
Sbjct: 1009 QKQVEDLKSQLV--AQDDSQRL-----VEQEVQEKLRETQEYNRIQKELEREKASLTLSL 1061
Query: 113 EQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGS 172
+ Q Q + + + A+R+ + + L Q+ L+ ++ + D
Sbjct: 1062 MEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADF---- 1117
Query: 173 LTSAALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVE 232
L E +L ++ + Q +L +AK L + S +E
Sbjct: 1118 -----LAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQ--------LRLRSTESQLE 1164
Query: 233 TLLTNHPPGHVLAALEHLAAEREAEIRSLCSG--DGLGDTEISRPQ-------------- 276
L PG+ A+ +A++ SL S LG SRP+
Sbjct: 1165 ALAAEQQPGN--------QAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGL 1216
Query: 277 APDQSD--------------SSQTLPSMVH-LIQEGWRTVGVLVSQRSTLLKERQVLT-- 319
PDQ+ S++ + S +H L Q+ W+T R + K + LT
Sbjct: 1217 EPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDT 1276
Query: 320 ----QRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQ--------- 366
++ +++++R++ + E + G ++ L +EL LH+ LQ
Sbjct: 1277 EAEKSQVHTELQDLQRQLSQNQEEKSKWEG-KQNSLESELMELHETMASLQSRLRRAELQ 1335
Query: 367 --DAAGHRQLLLRELQAKQQRILHWRQLVEETQEQ 399
+A G R+LL + ++ H + V E + Q
Sbjct: 1336 RMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQ 1370
Score = 35.0 bits (79), Expect = 0.21
Identities = 82/346 (23%), Positives = 128/346 (36%), Gaps = 66/346 (19%)
Query: 40 ADIWAYILQHVHSQRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLE 99
AD L+ H T+K+ G L QD + R+LE E AV R Q+LE
Sbjct: 1840 ADALQGALEQAHM--TLKERHGEL-----QDHKEQARRLEEELAVEGRRV------QALE 1886
Query: 100 LMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQD 159
+ D A+ E +ALL Q A + Q+H + + R LQD
Sbjct: 1887 EVLGDLRAESREQE-----------KALLALQQQCAEQAQEHEV---------ETRALQD 1926
Query: 160 MERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDH 219
+A+ + AL E R A RA+ LQ L
Sbjct: 1927 SWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEAL---------------- 1970
Query: 220 FGTSYQQWLSSVETLLTNHPPGHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPD 279
G ++ + LL + +LE A +A + + C E R Q +
Sbjct: 1971 -GKAHAALQGKEQHLLEQ---AELSRSLEASTATLQASLDA-CQAHSRQLEEALRIQEGE 2025
Query: 280 QSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSER 339
D V +Q+ ++QR L+ +Q +R Q L + + +RV + +
Sbjct: 2026 IQDQDLRYQEDVQQLQQA-------LAQRDEELRHQQ---EREQLLEKSLAQRVQENMIQ 2075
Query: 340 QVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQR 385
+ LG R E++ LH +ELQ ++ + EL+ QQR
Sbjct: 2076 EKQNLGQER--EEEEIRGLHQSVRELQLTLAQKEQEILELRETQQR 2119
Score = 33.9 bits (76), Expect = 0.47
Identities = 119/532 (22%), Positives = 207/532 (38%), Gaps = 56/532 (10%)
Query: 68 HQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRAL 127
H+ Q + ELE R + L LE ++ +AQ + + H+ R L
Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHS-TVLAREL 1625
Query: 128 LLRAQAGAMRRQQHTLRDPMQRLQNQLRRL-QDMERKAKVDVTFGSLTSAALGLEPV-VL 185
R Q +R+Q ++ LQ Q L QD+ER+ + L E + VL
Sbjct: 1626 QERDQEVKSQREQ------IEELQRQKEHLTQDLERRDQ---------ELMLQKERIQVL 1670
Query: 186 RDVRTACT-LRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVL 244
D RT T + + L+ + L +RG T Q+ L P
Sbjct: 1671 EDQRTRQTKILEEDLEQIKLSLRERGRELTT---------QRQLMQERAEEGKGPSKAQR 1721
Query: 245 AALEH---LAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDS-SQTLPSMVHLIQEGWRT 300
+LEH + ++E E+ C + + + + + Q Q + + L+ + +
Sbjct: 1722 GSLEHMKLILRDKEKEVE--CQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQE 1779
Query: 301 VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD 360
+ VL Q ++ ++ Q LQ ++E + R L ++++ L + + + + +
Sbjct: 1780 IVVLQQQLQEAREQGELKEQSLQSQLDEAQ-RALAQRDQELEALQQEQQQAQGQEERVKE 1838
Query: 361 QSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGE 420
++ LQ A + L+E + +++ +EQ R L + A + R ++ E
Sbjct: 1839 KADALQGALEQAHMTLKERHGE----------LQDHKEQARRL-EEELAVEGRRVQALEE 1887
Query: 421 VLALVQ---RKVVPTFEAVAPQSRELLRCLEEEVRHLPHILL--GTLLRHRPGELKPLPT 475
VL ++ R+ A+ Q E + E E R L L +L+ R EL+ L
Sbjct: 1888 VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRA 1947
Query: 476 VLPSI-HQLHPASPRGSSF-IALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWC 533
S HQ A R + AL GK LL A S + Q SL
Sbjct: 1948 ESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDA 2007
Query: 534 WDLLHMKTSLPPGLPTQE-LLQIQASQEKQQKENLGQALKRLEKLLKQALER 584
H + L L QE +Q Q + ++ + L QAL + ++ L+ ER
Sbjct: 2008 CQ-AHSR-QLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQER 2057
Score = 33.5 bits (75), Expect = 0.61
Identities = 122/570 (21%), Positives = 222/570 (38%), Gaps = 99/570 (17%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQH--------TQDTQRRALLLR 130
EL+A + ++ E +E+ + L EA T +EQ Q + Q + L+R
Sbjct: 677 ELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVR 736
Query: 131 AQAG------AMRRQQHTLRDPMQRLQNQLRRLQD-----MERKAKVDVTFGSL---TSA 176
+A A+ R + L + +Q L + L+ ++ + ++VT G L
Sbjct: 737 EKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQT 796
Query: 177 ALGLEPVVLRDVR----TACTLRAQFLQN-----LLLPQAKR------GSLPTPHDDHFG 221
+ V+ +VR T R+Q Q L QA++ H+
Sbjct: 797 VTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVN 856
Query: 222 TSYQQWLSSVETLLTNHPPGHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQS 281
++W E L +LE E E ++ TE+ QA +
Sbjct: 857 QLREKW--EKERSWHQQELAKALESLEREKMELEMRLKE-------QQTEMEAIQAQREE 907
Query: 282 DSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVL---TQRLQGLVEEVERRVLGSSE 338
+ +Q ++ + E T VS TLL+ ++ L +Q+L+ L ++++ + L E
Sbjct: 908 ERTQAESALCQMQLE---TEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQE 964
Query: 339 RQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILH----WRQLVE 394
+ L T+L+ + +EL++AA + L LQ + +L ++ VE
Sbjct: 965 TTGI--------LQTQLQ---EAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Query: 395 ETQEQV------RLLIKGNSASKTRLCRSPGEVLALVQR-KVVPTFEAVAPQSRELLRCL 447
+ + Q+ + L++ K R + + ++R K T + + R L+
Sbjct: 1014 DLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQE 1073
Query: 448 EEEVRHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHPASPRGSSFIALSHKLGLPPGKA 507
+ +R L ++ GE K L + + Q + + F+A +
Sbjct: 1074 ADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQ--EVKEKEADFLA----------QE 1121
Query: 508 SELLLPAAASLRQDLLLLQDQRSLWCWDLLHMKTSLPPGLPTQELLQIQASQEKQQKENL 567
++LL AS + Q + SLW + + L L + E Q++A +QQ N
Sbjct: 1122 AQLLEELEAS---HITEQQLRASLWAQEAKAAQLQL--RLRSTE-SQLEALAAEQQPGNQ 1175
Query: 568 GQALKRLEKL---LKQAL----ERIPELQG 590
QA +L L L+QAL E PEL G
Sbjct: 1176 AQAQAQLASLYSALQQALGSVCESRPELSG 1205
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 48.9 bits (115), Expect = 1e-05
Identities = 120/566 (21%), Positives = 216/566 (38%), Gaps = 77/566 (13%)
Query: 80 LEAA----VTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGA 135
LEAA + LR +++L + L E++ + A +A T+ T + LRA+
Sbjct: 1072 LEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSK 1131
Query: 136 MRRQQHTLRDPMQRLQNQLR--RLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACT 193
+ +Q ++ L+ L R ER + ++ G L A L
Sbjct: 1132 LEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQEL------------- 1178
Query: 194 LRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHLAAE 253
L Q + + T DH + +W + V + L + + E
Sbjct: 1179 --GHSQSALASAQRELAAFRTKVQDH-SKAEDEWKAQVARGRQEAERKNSLIS----SLE 1231
Query: 254 REAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLK 313
E I + + G+++ + +S+ SQ L + L+Q + ++RS+ L+
Sbjct: 1232 EEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALR 1291
Query: 314 ERQVLTQRLQGLVEEVER-RVLGSSERQVLILGLRRC-CLWTELKALHDQSQELQDAAGH 371
E +Q L EE E+ RV + RQ L R L ELKA ++ + + A
Sbjct: 1292 E------EVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALST 1345
Query: 372 RQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQR---- 427
QL QA +L + L ++ Q + K + + ++ G + A + R
Sbjct: 1346 LQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRE 1405
Query: 428 --KVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHP 485
+++P + VA Q R + E+ + + ++L H L
Sbjct: 1406 LGELIPLRQKVAEQERTAQQLRAEKASYAEQL-----------------SMLKKAHGLLA 1448
Query: 486 ASPRGSSFIALSHK--LGLPPGKASELLLPAAASLRQD--LLLLQDQRSLWCWDL-LHMK 540
RG A + L + +A E + A++R D L + QR L +
Sbjct: 1449 EENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVM 1508
Query: 541 TSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPG 600
T+ G + L + Q QE++QK L +++LE ++ +++ EL + D
Sbjct: 1509 TAKYEGAKVKVLEERQRFQEERQK--LTAQVEQLEVFQREQTKQVEELSKKLAD------ 1560
Query: 601 QAALSEELCQGLSLPQWRLRWVQAQG 626
Q + Q +L+ VQAQG
Sbjct: 1561 -------SDQASKVQQQKLKAVQAQG 1579
Score = 36.6 bits (83), Expect = 0.072
Identities = 74/368 (20%), Positives = 148/368 (40%), Gaps = 36/368 (9%)
Query: 77 KLELEAAVTRLRAEIQELDQSL-ELMERDTEAQDTAMEQARQHTQDTQ----RRALLLRA 131
K +++ + +L E +L L E + QD E +H++ TQ ++A L +
Sbjct: 306 KSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKE 365
Query: 132 QAGAMR------RQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVL 185
+ A++ + L+ + +L+ L +LQD + K +V L L E L
Sbjct: 366 LSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATL 425
Query: 186 RDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLA 245
T R + L+ + ++ + HF QQ S + L ++ ++
Sbjct: 426 AANNTQLQARVEMLET---ERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSI--SNLSQ 480
Query: 246 ALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLV 305
A E L +A L + +E++ A Q Q L + +E + +
Sbjct: 481 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD-QELAGLKQQAKEKQAQLAQTL 539
Query: 306 SQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQEL 365
Q+ + + ++L +++ E+++ +E+Q D +Q+L
Sbjct: 540 QQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEA--------------TRQDHAQQL 585
Query: 366 QDAAGHRQLLLRELQA--KQQRILHWRQL--VEETQEQVRLLIKGNSASKTRLCRSPGEV 421
AA R+ LRE A KQ L + +E Q+Q+++ + +++T + ++ E
Sbjct: 586 ATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQRE- 644
Query: 422 LALVQRKV 429
A + RKV
Sbjct: 645 KAELSRKV 652
Score = 36.6 bits (83), Expect = 0.072
Identities = 21/80 (26%), Positives = 41/80 (51%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
+LEA A+++ L Q L++ ++ T++ QA++ + R+ L+A R+
Sbjct: 605 QLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQ 664
Query: 139 QQHTLRDPMQRLQNQLRRLQ 158
+QH + + L+ QLR Q
Sbjct: 665 EQHEAQAQVAELELQLRSEQ 684
Score = 30.8 bits (68), Expect = 4.0
Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 26/158 (16%)
Query: 254 REAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLK 313
RE ++ L + +T ++ Q QS + + ++ EG + ++ +R +
Sbjct: 1473 REKYVQELAAVRADAETRLAEVQREAQSTAREL--EVMTAKYEGAKVK--VLEERQRFQE 1528
Query: 314 ERQVLTQRLQGL----------VEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQ 363
ERQ LT +++ L VEE+ +++ S + + +LKA+ Q
Sbjct: 1529 ERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKV--------QQQKLKAVQAQGG 1580
Query: 364 ELQDAAGHRQLLLRELQA----KQQRILHWRQLVEETQ 397
E Q A Q L ELQA K+Q H++ +E+ +
Sbjct: 1581 ESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAK 1618
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 48.1 bits (113), Expect = 2e-05
Identities = 137/640 (21%), Positives = 236/640 (36%), Gaps = 119/640 (18%)
Query: 66 YGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
+G + S + ++ E+ + R E++ L++ + L+ + Q +E + R
Sbjct: 168 WGLEGSQALSQQAEV---IVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARA 224
Query: 126 ALLLRAQAGAMRRQ-------QHTLRDPMQRLQNQLRRLQDMERKAKVDV---TFGSLTS 175
RA+A +R + L + QR +++RL + + SLTS
Sbjct: 225 EKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTS 284
Query: 176 AALGLEPVVLRDVRTACTLRAQFLQNLLLPQAK----RGSLPTPHDDHFGTSYQQWLSSV 231
A GLE + + + T RA + L Q + R L +D + ++ V
Sbjct: 285 KAEGLE----KSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQED-----LEAQVTLV 335
Query: 232 ETL---LTNHPPGHV------------LAALEHLAAEREA----------EIRSLCSGDG 266
E L + P V L ++HL +R++ ++SL
Sbjct: 336 ENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILA 395
Query: 267 LGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLV 326
L + E++R P S + L+ V L+ Q E ++L+G V
Sbjct: 396 LQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLKGQV 455
Query: 327 EEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRI 386
++ +V S+ Q ++ ++L D++ E++ + L EL Q+
Sbjct: 456 ASLQEKVTSQSQEQAILQ-----------RSLQDKAAEVEVERMGAKGLQLELSRAQEAR 504
Query: 387 LHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRC 446
W+Q +EQ+RL++ S+S+ L + +V E A Q L
Sbjct: 505 RRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKV------------EGAAAQLPSLNNR 552
Query: 447 LEEEVRHLPHILLGTLLR-----HRPGELKPLP----TVLPSIHQLHPASPRGSSFIALS 497
L VR + H + G + R E PLP V + QL R + + LS
Sbjct: 553 LSYAVRKV-HTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLS 611
Query: 498 HKL-------GLPPGKAS-ELLLPAAASLRQDLLLLQDQRSLWCWDL------------L 537
+L G+A + L A L Q+ L Q Q SL L
Sbjct: 612 ARLIQQEVGRAREQGEAERQQLSKVAQQLEQE--LQQTQESLASLGLQLEVARQGQQEST 669
Query: 538 HMKTSLPPGLPTQELLQIQASQEK------QQKENLGQALKRLEKLLKQALERIPELQGI 591
SL L Q+ L QA QEK + +E L +RL + ++ + + L+ I
Sbjct: 670 EEAASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQI 729
Query: 592 VGDWWEQPGQAALSEELCQGLSLPQWRLRWVQAQGALQKL 631
+AA +E Q L Q R + Q ++L
Sbjct: 730 -------QRRAAQEKERSQELRRLQEEARKEEGQRLARRL 762
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 48.1 bits (113), Expect = 2e-05
Identities = 137/640 (21%), Positives = 236/640 (36%), Gaps = 119/640 (18%)
Query: 66 YGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
+G + S + ++ E+ + R E++ L++ + L+ + Q +E + R
Sbjct: 132 WGLEGSQALSQQAEV---IVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARA 188
Query: 126 ALLLRAQAGAMRRQ-------QHTLRDPMQRLQNQLRRLQDMERKAKVDV---TFGSLTS 175
RA+A +R + L + QR +++RL + + SLTS
Sbjct: 189 EKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTS 248
Query: 176 AALGLEPVVLRDVRTACTLRAQFLQNLLLPQAK----RGSLPTPHDDHFGTSYQQWLSSV 231
A GLE + + + T RA + L Q + R L +D + ++ V
Sbjct: 249 KAEGLE----KSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQED-----LEAQVTLV 299
Query: 232 ETL---LTNHPPGHV------------LAALEHLAAEREA----------EIRSLCSGDG 266
E L + P V L ++HL +R++ ++SL
Sbjct: 300 ENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILA 359
Query: 267 LGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLV 326
L + E++R P S + L+ V L+ Q E ++L+G V
Sbjct: 360 LQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLKGQV 419
Query: 327 EEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRI 386
++ +V S+ Q ++ ++L D++ E++ + L EL Q+
Sbjct: 420 ASLQEKVTSQSQEQAILQ-----------RSLQDKAAEVEVERMGAKGLQLELSRAQEAR 468
Query: 387 LHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRC 446
W+Q +EQ+RL++ S+S+ L + +V E A Q L
Sbjct: 469 RRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKV------------EGAAAQLPSLNNR 516
Query: 447 LEEEVRHLPHILLGTLLR-----HRPGELKPLP----TVLPSIHQLHPASPRGSSFIALS 497
L VR + H + G + R E PLP V + QL R + + LS
Sbjct: 517 LSYAVRKV-HTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLS 575
Query: 498 HKL-------GLPPGKAS-ELLLPAAASLRQDLLLLQDQRSLWCWDL------------L 537
+L G+A + L A L Q+ L Q Q SL L
Sbjct: 576 ARLIQQEVGRAREQGEAERQQLSKVAQQLEQE--LQQTQESLASLGLQLEVARQGQQEST 633
Query: 538 HMKTSLPPGLPTQELLQIQASQEK------QQKENLGQALKRLEKLLKQALERIPELQGI 591
SL L Q+ L QA QEK + +E L +RL + ++ + + L+ I
Sbjct: 634 EEAASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQI 693
Query: 592 VGDWWEQPGQAALSEELCQGLSLPQWRLRWVQAQGALQKL 631
+AA +E Q L Q R + Q ++L
Sbjct: 694 -------QRRAAQEKERSQELRRLQEEARKEEGQRLARRL 726
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 48.1 bits (113), Expect = 2e-05
Identities = 137/640 (21%), Positives = 236/640 (36%), Gaps = 119/640 (18%)
Query: 66 YGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
+G + S + ++ E+ + R E++ L++ + L+ + Q +E + R
Sbjct: 79 WGLEGSQALSQQAEV---IVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARA 135
Query: 126 ALLLRAQAGAMRRQ-------QHTLRDPMQRLQNQLRRLQDMERKAKVDV---TFGSLTS 175
RA+A +R + L + QR +++RL + + SLTS
Sbjct: 136 EKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTS 195
Query: 176 AALGLEPVVLRDVRTACTLRAQFLQNLLLPQAK----RGSLPTPHDDHFGTSYQQWLSSV 231
A GLE + + + T RA + L Q + R L +D + ++ V
Sbjct: 196 KAEGLE----KSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQED-----LEAQVTLV 246
Query: 232 ETL---LTNHPPGHV------------LAALEHLAAEREA----------EIRSLCSGDG 266
E L + P V L ++HL +R++ ++SL
Sbjct: 247 ENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILA 306
Query: 267 LGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLV 326
L + E++R P S + L+ V L+ Q E ++L+G V
Sbjct: 307 LQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLKGQV 366
Query: 327 EEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRI 386
++ +V S+ Q ++ ++L D++ E++ + L EL Q+
Sbjct: 367 ASLQEKVTSQSQEQAILQ-----------RSLQDKAAEVEVERMGAKGLQLELSRAQEAR 415
Query: 387 LHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRC 446
W+Q +EQ+RL++ S+S+ L + +V E A Q L
Sbjct: 416 RRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKV------------EGAAAQLPSLNNR 463
Query: 447 LEEEVRHLPHILLGTLLR-----HRPGELKPLP----TVLPSIHQLHPASPRGSSFIALS 497
L VR + H + G + R E PLP V + QL R + + LS
Sbjct: 464 LSYAVRKV-HTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLS 522
Query: 498 HKL-------GLPPGKAS-ELLLPAAASLRQDLLLLQDQRSLWCWDL------------L 537
+L G+A + L A L Q+ L Q Q SL L
Sbjct: 523 ARLIQQEVGRAREQGEAERQQLSKVAQQLEQE--LQQTQESLASLGLQLEVARQGQQEST 580
Query: 538 HMKTSLPPGLPTQELLQIQASQEK------QQKENLGQALKRLEKLLKQALERIPELQGI 591
SL L Q+ L QA QEK + +E L +RL + ++ + + L+ I
Sbjct: 581 EEAASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQI 640
Query: 592 VGDWWEQPGQAALSEELCQGLSLPQWRLRWVQAQGALQKL 631
+AA +E Q L Q R + Q ++L
Sbjct: 641 -------QRRAAQEKERSQELRRLQEEARKEEGQRLARRL 673
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/136 (22%), Positives = 67/136 (49%), Gaps = 4/136 (2%)
Query: 76 RKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGA 135
+++E + + RLR E + L Q +E +E+++ A + Q + +++ +
Sbjct: 373 KEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAV 432
Query: 136 MRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLR 195
+R+Q + + +Q+ Q+ +R+LQ+ + ++ F ++ LE LR+ T LR
Sbjct: 433 VRQQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDF--VSHLETELEQSRLRETETLGALR 490
Query: 196 AQFLQNLLLPQAKRGS 211
+Q+ +L KR S
Sbjct: 491 E--MQDKVLDMEKRNS 504
>gi|167555110 kinesin family member C1 [Homo sapiens]
Length = 673
Score = 44.3 bits (103), Expect = 3e-04
Identities = 66/244 (27%), Positives = 100/244 (40%), Gaps = 37/244 (15%)
Query: 275 PQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRV- 333
P P Q + +P M + R L Q L E + +R Q L +E ++
Sbjct: 110 PAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQD 169
Query: 334 -LGSSERQVLILGLRRCCLWTELKALHDQSQ--------------ELQDAAGHRQLLLRE 378
L +++QV LG R L L + Q++ EL++ ++ L++E
Sbjct: 170 QLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQE 229
Query: 379 LQAKQQRILHWRQ-LVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVA 437
LQ KQ + R+ L+ + +E+ R L S+ L S EV +L Q V A+
Sbjct: 230 LQKKQVELQEERRGLMSQLEEKERRL----QTSEAALSSSQAEVASLRQETVAQA--ALL 283
Query: 438 PQSRELLRCLEEEVRHLPHIL------LGTLLRHR---PGELKPLPTVLPSIHQLHPASP 488
+ E L LE E R L + L + R R PGE P P +L L P+ P
Sbjct: 284 TEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLL-----LFPSGP 338
Query: 489 RGSS 492
G S
Sbjct: 339 GGPS 342
>gi|117956403 rabaptin, RAB GTPase binding effector protein 2 [Homo
sapiens]
Length = 569
Score = 42.7 bits (99), Expect = 0.001
Identities = 115/554 (20%), Positives = 211/554 (38%), Gaps = 125/554 (22%)
Query: 83 AVTRLRAEIQELDQSLELMERDT----EAQDTAMEQAR-QHTQDTQRRALLLRAQAGAMR 137
AV ++ + QE SL+ + +D+ EAQ TA++Q R Q QD + + + G +
Sbjct: 71 AVAAVQRQCQEEVASLQAILKDSISSYEAQITALKQERQQQQQDCEEK----ERELGRL- 125
Query: 138 RQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLRAQ 197
+Q + P+ L+ Q+ + + K L L +E + +++ +
Sbjct: 126 KQLLSRAYPLDSLEKQMEKAHEDSEK---------LREIVLPMEKEI-EELKAKLLRAEE 175
Query: 198 FLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHLA------ 251
+Q + Q + P+ H S E L + P L LE L+
Sbjct: 176 LIQEI---QRRPRHAPSLH------------GSTELLPLSRDPSPPLEPLEELSGDGGPA 220
Query: 252 -------AEREAEIRSLCSGDGLGDTEISRPQ-----APDQSDSSQ------TLPSMVHL 293
+ A I S G G+G + S PQ +P+Q +++ +P ++L
Sbjct: 221 AEAFAHNCDDSASISSFSLGGGVGSSS-SLPQSRQGLSPEQEETASLVSTGTLVPEGIYL 279
Query: 294 IQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWT 353
G++ V T ++ Q ++LQ +E V R ER L GLRR
Sbjct: 280 PPPGYQLV------PDTQWEQLQTEGRQLQKDLESVSR------ERDELQEGLRR----- 322
Query: 354 ELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRL----------- 402
+D A Q+LL ++Q +Q + + V + QE+V+L
Sbjct: 323 ----------SNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQLQMAELVTTHKC 372
Query: 403 -------LIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLP 455
L + N + S + ++ + + P+ ++LL C +E R
Sbjct: 373 LHHEVKRLNEENQGLRAEQLPSSAPQGSQQEQGEEESLPSSVPELQQLLCCTRQEAR--- 429
Query: 456 HILLGTLLRHRPGELKPLPTVLPSIHQLHPASPRGSSFIALSHKLGLPPGKASELLLPAA 515
L G + ++ L + +S L +L + + +E+L +
Sbjct: 430 ----ARLQAQEHGAERLRIEIVTLREALEEETVARAS---LEGQLRV-QREETEVLEASL 481
Query: 516 ASLRQDLLLLQDQRSLWCWDLLHMKTSLPPGLPTQELLQIQASQEKQQKENLGQALKRLE 575
SLR ++ +Q ++S K LP L Q ++ E + E + + RL
Sbjct: 482 CSLRTEMERVQQEQS---------KAQLPDLLSEQRAKVLRLQAELETSEQVQRDFVRLS 532
Query: 576 KLLKQALERIPELQ 589
+ L+ LERI + +
Sbjct: 533 QALQVRLERIRQAE 546
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 17/112 (15%)
Query: 69 QDSPQVRRKLELEAAVTR------LRAEIQELDQSLELMERDT-----------EAQDTA 111
++ PQ +R+L+ E R LR E QE +Q + + R+ E Q+
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 112 MEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
EQ + Q +RR LR + R QQ +R + QLRR Q+ ER+
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Query: 77 KLELEAAVTRLRAEIQE-LDQSLELMERDTEAQDTAMEQA-RQHTQDTQRRALLLRAQAG 134
K E E RL+ E +E L+Q L+ E + Q+ EQ ++ + +RR LL+++
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 135 AMRRQQHTLRDPMQRLQNQLRRLQDMER 162
RRQQ R+ +R + +L+R ++ ER
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEER 667
Score = 38.9 bits (89), Expect = 0.015
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 73 QVRRKLELEAAVTR--LRAEIQELDQSLELMERDTEA-QDTAMEQARQHTQDTQRRALLL 129
Q+RRK E E + R + + +Q E E+ Q+ EQ + Q+ +RR L
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Query: 130 RAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKV 166
R + RR+Q R+ R + QLRR Q + R+ ++
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Score = 38.9 bits (89), Expect = 0.015
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQ 132
Q+RR+ E E +LR E QE ++ + + R+ Q EQ + Q +R L R Q
Sbjct: 350 QLRREQEEERREQQLRRE-QEEERREQQLRRE---QQLRREQQLRREQQLRREQQLRREQ 405
Query: 133 AGAMRRQQHTLRDPMQRLQNQLRRLQDMER 162
+RR+Q R+ R + QLRR Q+ ER
Sbjct: 406 Q--LRREQQLRREQQLRREQQLRREQEEER 433
Score = 37.0 bits (84), Expect = 0.055
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLEL---MERDTEAQDTAMEQARQHTQDTQRRALLL 129
Q+RR+ E E +LR E +E + +L E + Q EQ + Q +R L
Sbjct: 338 QLRREQE-ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Query: 130 RAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
R Q +RR+Q R+ R + QLRR Q + R+
Sbjct: 397 REQQ--LRREQQLRREQQLRREQQLRREQQLRRE 428
Score = 35.8 bits (81), Expect = 0.12
Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 53 QRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAM 112
+ ++K+ L Q+ Q +++L E + R + E + Q +++ Q
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 113 EQARQHTQDTQRRALLLRAQAGAMRRQQHTLRD-PMQRLQNQLRRLQDMERKAKV 166
+ + + +RR LR + RR+Q R+ +R + QLRR Q + R+ ++
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Score = 35.0 bits (79), Expect = 0.21
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 75 RRKLELEAAVTRLRAEIQE--LDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQ 132
RR+ + E + R E QE +Q L + + Q EQ + + RR +
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 133 AGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKV 166
+RR+Q R+ R + QLRR Q + R+ ++
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Score = 35.0 bits (79), Expect = 0.21
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 17/134 (12%)
Query: 47 LQHVHSQRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVT---RLRAEIQELDQSLELMER 103
LQ +R ++ R + W + + RR+ L A +LR E Q L + E ++R
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 104 DTEAQDTAMEQARQHTQDTQ---RRALLLRAQAGAMRRQ----QHTLRDPMQRLQNQL-- 154
+ + EQ RQ+ ++ Q LLR + RRQ Q+ +Q+ + QL
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 155 -----RRLQDMERK 163
RR Q+ E+K
Sbjct: 976 EEPEKRRRQEREKK 989
Score = 35.0 bits (79), Expect = 0.21
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 69 QDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALL 128
++ P+ RR+ E E R E+Q+ ++ L ER+ + Q R+ + Q L
Sbjct: 1095 REEPEKRRRQERERQC-REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 129 LRAQAGAMRRQ----QHTLRDPMQRLQNQLRRLQDMERK 163
LR + RRQ Q+ + +Q+ + QL R + +R+
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192
Score = 33.1 bits (74), Expect = 0.80
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 69 QDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALL 128
Q+ + +K E E RL+ E +E L+ E + +Q + Q+ +RR
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 129 LRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKV 166
L+ + R QQ +R + QLRR Q+ R+ ++
Sbjct: 489 LKLEEEERREQQ-------ERREQQLRREQEERREQRL 519
Score = 32.7 bits (73), Expect = 1.0
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 11/100 (11%)
Query: 75 RRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAG 134
+R+L+ R E+Q+ ++ L ER+T + Q R+ + Q LLR +
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099
Query: 135 AMRRQQHTLR----DPMQRLQNQL-------RRLQDMERK 163
RRQ+ + + +Q+ + QL RR Q++ER+
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Score = 32.3 bits (72), Expect = 1.4
Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQ 132
Q+RR+ +L +LR E Q+L + +L ++ E+ Q + +R L R Q
Sbjct: 394 QLRREQQLRRE-QQLRRE-QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 133 AGA---MRRQQHTLRDPMQRLQNQLRRLQDMERKAK 165
++R++ T R +R + QL+R Q+ ER+ +
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Score = 30.8 bits (68), Expect = 4.0
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 12/105 (11%)
Query: 70 DSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLL 129
+ P+ RR+ E E R E+Q+ ++ L ER+ + Q R+ + Q LL
Sbjct: 976 EEPEKRRRQEREKKY-REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 130 RAQAGAMRRQ----QHTLRDPMQRLQNQL-------RRLQDMERK 163
R + R Q Q+ + +Q+ + QL RR Q++ER+
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Score = 30.0 bits (66), Expect = 6.8
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 69 QDSPQVRRKLELEAAVTRL-RAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRAL 127
Q+ + R K E E +L + E + Q L+ + + Q E+ + Q+ +R
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 128 LLRAQAGAMRRQQHTLRDPM-QRLQNQLRRLQDMERKAKV 166
L R + RRQQ + +R Q QLRR Q R+ ++
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL 659
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 42.0 bits (97), Expect = 0.002
Identities = 75/364 (20%), Positives = 147/364 (40%), Gaps = 26/364 (7%)
Query: 76 RKLELEAAVTRLRAEIQELDQSLELMERDTE-------AQDTAMEQARQHTQDTQRRALL 128
+ L+L+ + +LR + +E ++ + E + A +T + + ++ + +RR L
Sbjct: 682 QNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILG 741
Query: 129 LRAQAGAMR-------RQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLE 181
L Q R + LRD +QRL+ + ++L++ ++ + GSL +A LE
Sbjct: 742 LEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEE--GSLAAAKRALE 799
Query: 182 PVVLRDVRTACTL--RAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHP 239
+ R L Q L L + K+ + + +V+ L
Sbjct: 800 ARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELE 859
Query: 240 P--GHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEG 297
AL+ L A+ E + + + ++ A + +S L + IQ
Sbjct: 860 KIGEDSKQALQQLQAQLE-DYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRL 918
Query: 298 WRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRR--CCLWTEL 355
+ + ++R T ++++L QRLQGL +E E + +R + GL L TEL
Sbjct: 919 RQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETEL 978
Query: 356 KALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLC 415
+ + L D + + +L+ + ++ R ++ + L + N KTRL
Sbjct: 979 DEEKNTVELLTDRVNRGRDQVDQLRTE---LMQERSARQDLECDKISLERQNKDLKTRLA 1035
Query: 416 RSPG 419
S G
Sbjct: 1036 SSEG 1039
Score = 40.4 bits (93), Expect = 0.005
Identities = 85/335 (25%), Positives = 135/335 (40%), Gaps = 60/335 (17%)
Query: 76 RKLELEAAVTRLRAEIQELDQSLELMERDTEAQ-DTAMEQARQHTQDTQRRALLLRAQAG 134
+K L+ V RL E++++ + + + +AQ + E+AR+ D QR+A ++A
Sbjct: 843 QKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE 902
Query: 135 AMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTL 194
L+D +QRL+ L+ Q A++D L GLE R+
Sbjct: 903 KTSGGLSRLQDEIQRLRQALQASQAERDTARLDKEL--LAQRLQGLEQEAENKKRSQDD- 959
Query: 195 RAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLL--TNHPPGHVLAALEHLAA 252
RA+ L+ L + K L T D+ T VE L N V L
Sbjct: 960 RARQLKGL---EEKVSRLETELDEEKNT--------VELLTDRVNRGRDQVDQLRTELMQ 1008
Query: 253 EREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLL 312
ER A D E + Q+ +T + EG++ +SQ L
Sbjct: 1009 ERSAR----------QDLECDKISLERQNKDLKTRLAS----SEGFQKPSASLSQ---LE 1051
Query: 313 KERQVLTQRLQGLVEEVERRVLGSS----ERQVLILGLRRCCLWTELKALHDQSQELQDA 368
+ Q+L +RLQ EE E+ VL S+ ER+V L ++ + D+ Q + D
Sbjct: 1052 SQNQLLQERLQ--AEEREKTVLQSTNRKLERKVKELSIQ----------IEDERQHVNDQ 1099
Query: 369 AGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLL 403
QL LR K+Q V+E +E++ L
Sbjct: 1100 KD--QLSLRVKALKRQ--------VDEAEEEIERL 1124
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 41.2 bits (95), Expect = 0.003
Identities = 50/186 (26%), Positives = 83/186 (44%), Gaps = 30/186 (16%)
Query: 69 QDSPQVRRKLE-----LEAAVTRLRA-----EIQELDQSLELMER--DTEAQDTAMEQAR 116
Q+ Q RR+LE L + +LRA E+ D+ E + R D E A+EQ
Sbjct: 648 QNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQM 707
Query: 117 Q-HTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRL---------QDMERKAKV 166
+ H + Q++ LR + ++ +RD Q+LQ + +L +D ER+ K+
Sbjct: 708 ESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKL 767
Query: 167 DVTF------GSLTSAALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHF 220
+ GLE V R+++T LR F+Q+L K S+ +DD
Sbjct: 768 EKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKK--SVELDNDDGG 825
Query: 221 GTSYQQ 226
G++ Q+
Sbjct: 826 GSAAQK 831
>gi|116008447 CAP-GLY domain containing linker protein 2 isoform 1
[Homo sapiens]
Length = 1046
Score = 41.2 bits (95), Expect = 0.003
Identities = 109/482 (22%), Positives = 180/482 (37%), Gaps = 84/482 (17%)
Query: 15 VEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKI------------RGN 62
V +G P + A +R+ +G A L H S ++ + R
Sbjct: 285 VIRIGFPSTSPAKAKKTKRMAMGVSA------LTHSPSSSSISSVSSVASSVGGRPSRSG 338
Query: 63 LLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLE--LMERDTEAQDTAMEQARQHTQ 120
LL + S + RK+ + T L+ ++E Q +E L ERD E + A +A H
Sbjct: 339 LLT---ETSSRYARKI---SGTTALQEALKEKQQHIEQLLAERDLERAEVA--KATSHIC 390
Query: 121 DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL 180
+ ++ LL+AQ + + + ++LQ + R L + RK KVD++ L +
Sbjct: 391 EVEKEIALLKAQ------HEQYVAEAEEKLQ-RARLLVESVRKEKVDLS-NQLEEERRKV 442
Query: 181 EPVVLR---------DVRTACTLR----AQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQW 227
E + R D+ T L + Q+LLL +A+ L D+
Sbjct: 443 EDLQFRVEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADN-------- 494
Query: 228 LSSVETLLTNHPPGHVLAALEHLAAER-EAEIRSLCSGDGLGDTEISRPQAPDQSDSSQT 286
L T VL E L R E E C L + P PD ++ +
Sbjct: 495 -----RLTTVAEKSRVLQLEEELTLRRGEIEELQQC----LLHSGPPPPDHPDAAEILRL 545
Query: 287 LPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSER--QVLIL 344
++ +E R GVL + LK Q +L+ E+ + V G ++ Q
Sbjct: 546 RERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAGLKDKVQQATSE 605
Query: 345 GLRRCCLW---------TELKALHDQSQELQDAAGHRQLLLRELQA-----KQQRILHWR 390
+ W K+L D L G +Q + EL+A K + L
Sbjct: 606 NMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVMEGIKMEHQLELG 665
Query: 391 QLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEE 450
L + + + +K A + +L + E LA +QR E A Q R L+ +++
Sbjct: 666 NLQAKHDLETAMHVKEKEALREKL-QEAQEELAGLQRHWRAQLEVQASQHRLELQEAQDQ 724
Query: 451 VR 452
R
Sbjct: 725 RR 726
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 41.2 bits (95), Expect = 0.003
Identities = 119/525 (22%), Positives = 206/525 (39%), Gaps = 83/525 (15%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
EL+A RL +E++EL Q ELM+ E + E +R H + Q R + +
Sbjct: 868 ELKATRKRLDSELKELRQ--ELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSA 925
Query: 139 QQHTLRDPMQRLQNQLRRLQ-DMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLRAQ 197
Q+ RD M + L+ LQ D E+ V +L L+ ++ R A T + Q
Sbjct: 926 QKE--RDEM---ETHLQSLQFDKEQMVAVTEANEALKKQIEELQ----QEARKAITEQKQ 976
Query: 198 FLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHLAAEREAE 257
++ L GS T T ++ + ++V G + L+ A +EA
Sbjct: 977 KMRRL-------GSDLTSAQKEMKTKHKAYENAV---------GILSRRLQEALAAKEA- 1019
Query: 258 IRSLCSGDGLGDTEISRPQAP-DQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLL-KER 315
D E+ + +A SDSS L + ++ + VS TLL KE
Sbjct: 1020 ----------ADAELGQLRAQGGSSDSSLALHERIQALEAELQA----VSHSKTLLEKEL 1065
Query: 316 QVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLL 375
Q + +EE +VL + G R+ ++K L + +++ L
Sbjct: 1066 QEVIALTSQELEESREKVLELEDELQESRGFRK-----KIKRLEESNKK----------L 1110
Query: 376 LRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRK------- 428
EL+ ++ ++ Q +E +L + + L + +V A++QRK
Sbjct: 1111 ALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQM 1170
Query: 429 --VVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHPA 486
+V +A + +E + L+E+V + G RH L V +L
Sbjct: 1171 KHLVQALQASLEKEKEKVNSLKEQVA-AAKVEAGHNRRHFKAASLELSEVK---KELQAK 1226
Query: 487 SPRGSSFIALSHKLGLPPGKASELLLPAAASL---RQDLLLLQDQRSLWCWDLLHMKTSL 543
A + L + GK S+ + A L R L LLQ Q L +
Sbjct: 1227 EHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQ-------LDEQLSKQ 1279
Query: 544 PPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPEL 588
P G E L+ + Q++++ ++L Q L E+ ++ LE + +L
Sbjct: 1280 PVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQL 1324
Score = 37.4 bits (85), Expect = 0.042
Identities = 39/178 (21%), Positives = 75/178 (42%), Gaps = 17/178 (9%)
Query: 62 NLLWYGHQDSPQVRR-KLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQ 120
NL W Q +++ K +L+ + R E++ L Q L+ ++ + +E A++
Sbjct: 1288 NLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSE-------LEMAQEDLS 1340
Query: 121 DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL 180
TQ+ +L+A+ ++ TL Q+L+ LRR RK S++
Sbjct: 1341 MTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEP-----KGEASSSNPA 1395
Query: 181 EPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNH 238
P+ + D C + A L+ LL P P + + +Q + S++ + H
Sbjct: 1396 TPIKIPD----CPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEH 1449
Score = 33.5 bits (75), Expect = 0.61
Identities = 99/449 (22%), Positives = 166/449 (36%), Gaps = 80/449 (17%)
Query: 81 EAAVTRLRAEIQELDQSLELMER--DTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
+A + +LRA+ D SL L ER EA+ A+ ++ + + + L +Q R
Sbjct: 1021 DAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESR 1080
Query: 139 QQHT-LRDPMQR---LQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRD----VRT 190
++ L D +Q + +++RL++ +K +++ LG LR+ + T
Sbjct: 1081 EKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILET 1140
Query: 191 ACTLRAQFLQNLLLP-------------------QAKRGSLPTPHDDHFGTSYQQWLSSV 231
A R L L L QA + SL + Q + V
Sbjct: 1141 ALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKV 1200
Query: 232 ETLLTNHPPGHV-------------LAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAP 278
E H H L A EHL + +AE L +G EI++ QA
Sbjct: 1201 EA---GHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAE 1257
Query: 279 DQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSE 338
+ E + +L Q L ++ V Q ++ L EV+++ E
Sbjct: 1258 ---------------LAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQK-----E 1297
Query: 339 RQVLILGLRRCCLWTE---LKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEE 395
R+ I L++ TE K L Q LQ+ ++ +L Q+ + V E
Sbjct: 1298 RE--IQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSE 1355
Query: 396 TQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLP 455
+ ++ L++ N K L R + + P EA + ++ + V P
Sbjct: 1356 LKNNMKTLLQQNQQLKLDLRRGAAKT------RKEPKGEASSSNPATPIKIPDCPV---P 1406
Query: 456 HILLGTLLRHRPGELK-PLPTVLPSIHQL 483
LL LLR P K PL + + QL
Sbjct: 1407 ASLLEELLRPPPAVSKEPLKNLNSCLQQL 1435
Score = 33.1 bits (74), Expect = 0.80
Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 77 KLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAM 136
K+ LEAA+ ++ +ELD+ +E TE +E+ R+ + L+ + A+
Sbjct: 775 KIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAAL 834
Query: 137 RRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVT 169
++Q MQ+++ Q + + M + D T
Sbjct: 835 KKQ-------MQKIKEQFLQQKVMVEAYRRDAT 860
Score = 32.0 bits (71), Expect = 1.8
Identities = 21/91 (23%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
Query: 75 RRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAG 134
+R+ L + V L+ +L++++ ++ EA++ ++ + Q + + L A+
Sbjct: 461 QRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVE 520
Query: 135 AMRRQQ-------HTLRDPMQRLQNQLRRLQ 158
M+R H LR M LQ+QL+++Q
Sbjct: 521 DMQRSMLSKDNTVHDLRQQMTALQSQLQQVQ 551
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/136 (23%), Positives = 68/136 (50%), Gaps = 15/136 (11%)
Query: 76 RKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGA 135
+++E + + RLR E + L Q +E +E+ Q T ++A ++ +++ +
Sbjct: 373 KEMEEQIEIKRLRTENRLLKQRIETLEK---GQVTRAQEAEEN--------YVIKRELAV 421
Query: 136 MRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLR 195
+R+Q + + +Q+ Q+ +R+LQ+ + ++ F ++ LE LR+ T LR
Sbjct: 422 VRQQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDF--VSHLETELEQSRLRETETLGALR 479
Query: 196 AQFLQNLLLPQAKRGS 211
+Q+ +L KR S
Sbjct: 480 E--MQDKVLDMEKRNS 493
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 40.8 bits (94), Expect = 0.004
Identities = 78/355 (21%), Positives = 139/355 (39%), Gaps = 64/355 (18%)
Query: 66 YGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
Y + ++ KLE E R E+ + + + +L+++ + +D ++ ++
Sbjct: 256 YEKRKEQKMLEKLEFER-----RLELGQREHT-QLLQQSSSQKDEILQTVKEEQS----- 304
Query: 126 ALLLRAQAGAMRRQQHTLRDPMQRLQNQLRR------------LQDMERKAKVDVTFGSL 173
R + G Q+H L QRLQ QL++ LQD +R+ K SL
Sbjct: 305 ----RLEQGLSEHQRH-LNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSL 359
Query: 174 TSAALGLEPVVLRDVRTACTLR----AQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLS 229
+ + +E ++ +LR A +Q +L K + ++ QQ S
Sbjct: 360 ENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACS 419
Query: 230 SV-------------ETLLTNHPPGHVL-------AALEHLAAEREAEIRSLCSGDGLGD 269
S+ + + N +L AA E L +++ R + S L +
Sbjct: 420 SMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIE 479
Query: 270 TEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEV 329
TE+ + + S S+ +I E + L+ Q LLKE+Q + L+ ++ E+
Sbjct: 480 TELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQ---LLKEKQQREEELREILTEL 536
Query: 330 ERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQL--LLRELQAK 382
E + E LI + L S +LQ+ RQL LL EL A+
Sbjct: 537 EAKSETRQENYWLI-------QYQRLLNQKPLSLKLQEEGMERQLVALLEELSAE 584
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 40.8 bits (94), Expect = 0.004
Identities = 78/355 (21%), Positives = 139/355 (39%), Gaps = 64/355 (18%)
Query: 66 YGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
Y + ++ KLE E R E+ + + + +L+++ + +D ++ ++
Sbjct: 256 YEKRKEQKMLEKLEFER-----RLELGQREHT-QLLQQSSSQKDEILQTVKEEQS----- 304
Query: 126 ALLLRAQAGAMRRQQHTLRDPMQRLQNQLRR------------LQDMERKAKVDVTFGSL 173
R + G Q+H L QRLQ QL++ LQD +R+ K SL
Sbjct: 305 ----RLEQGLSEHQRH-LNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSL 359
Query: 174 TSAALGLEPVVLRDVRTACTLR----AQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLS 229
+ + +E ++ +LR A +Q +L K + ++ QQ S
Sbjct: 360 ENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACS 419
Query: 230 SV-------------ETLLTNHPPGHVL-------AALEHLAAEREAEIRSLCSGDGLGD 269
S+ + + N +L AA E L +++ R + S L +
Sbjct: 420 SMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIE 479
Query: 270 TEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEV 329
TE+ + + S S+ +I E + L+ Q LLKE+Q + L+ ++ E+
Sbjct: 480 TELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQ---LLKEKQQREEELREILTEL 536
Query: 330 ERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQL--LLRELQAK 382
E + E LI + L S +LQ+ RQL LL EL A+
Sbjct: 537 EAKSETRQENYWLI-------QYQRLLNQKPLSLKLQEEGMERQLVALLEELSAE 584
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 40.8 bits (94), Expect = 0.004
Identities = 78/355 (21%), Positives = 139/355 (39%), Gaps = 64/355 (18%)
Query: 66 YGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
Y + ++ KLE E R E+ + + + +L+++ + +D ++ ++
Sbjct: 256 YEKRKEQKMLEKLEFER-----RLELGQREHT-QLLQQSSSQKDEILQTVKEEQS----- 304
Query: 126 ALLLRAQAGAMRRQQHTLRDPMQRLQNQLRR------------LQDMERKAKVDVTFGSL 173
R + G Q+H L QRLQ QL++ LQD +R+ K SL
Sbjct: 305 ----RLEQGLSEHQRH-LNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSL 359
Query: 174 TSAALGLEPVVLRDVRTACTLR----AQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLS 229
+ + +E ++ +LR A +Q +L K + ++ QQ S
Sbjct: 360 ENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACS 419
Query: 230 SV-------------ETLLTNHPPGHVL-------AALEHLAAEREAEIRSLCSGDGLGD 269
S+ + + N +L AA E L +++ R + S L +
Sbjct: 420 SMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIE 479
Query: 270 TEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEV 329
TE+ + + S S+ +I E + L+ Q LLKE+Q + L+ ++ E+
Sbjct: 480 TELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQ---LLKEKQQREEELREILTEL 536
Query: 330 ERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQL--LLRELQAK 382
E + E LI + L S +LQ+ RQL LL EL A+
Sbjct: 537 EAKSETRQENYWLI-------QYQRLLNQKPLSLKLQEEGMERQLVALLEELSAE 584
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAM--------EQARQHTQDTQR 124
+++ ++E A++ L E ++ Q E M R+ EAQ E+ R+ + Q
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE 376
Query: 125 RALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
+ LR Q +R+Q+ LR +RLQ Q +RL D E +
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEER 415
Score = 34.7 bits (78), Expect = 0.27
Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
+L+ LR E++ L+ L+ + +A ++ +Q Q+ + +LR Q R
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE---MLREQEAQRVR 355
Query: 139 QQHTLRDPMQRLQNQLRRLQDMERKAK 165
+Q L + +RL+ Q + LQ+ + +
Sbjct: 356 EQERLCEQNERLREQQKTLQEQGERLR 382
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 73 QVRRKLELEAAVTRLRAE-IQELDQSLELMERDTEAQDTAMEQA---RQHTQDTQRRALL 128
Q +R E E + A+ ++E ++ E ER E Q T EQ R+ Q +++
Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394
Query: 129 LRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
LR + +++Q+ L D +RL + RLQ E +
Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAM--------EQARQHTQDTQR 124
+++ ++E A++ L E ++ Q E M R+ EAQ E+ R+ + Q
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE 376
Query: 125 RALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
+ LR Q +R+Q+ LR +RLQ Q +RL D E +
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEER 415
Score = 34.7 bits (78), Expect = 0.27
Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
+L+ LR E++ L+ L+ + +A ++ +Q Q+ + +LR Q R
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE---MLREQEAQRVR 355
Query: 139 QQHTLRDPMQRLQNQLRRLQDMERKAK 165
+Q L + +RL+ Q + LQ+ + +
Sbjct: 356 EQERLCEQNERLREQQKTLQEQGERLR 382
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 73 QVRRKLELEAAVTRLRAE-IQELDQSLELMERDTEAQDTAMEQA---RQHTQDTQRRALL 128
Q +R E E + A+ ++E ++ E ER E Q T EQ R+ Q +++
Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394
Query: 129 LRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
LR + +++Q+ L D +RL + RLQ E +
Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 40.4 bits (93), Expect = 0.005
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 8/127 (6%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQ 132
++R+ +L A + RL+ EL++ LE +ER+ +A+ E R+ + QR A L + +
Sbjct: 1378 ELRQIDKLRAELRRLQRRRTELERQLEELERERQAR---REAEREVQRLQQRLAALEQEE 1434
Query: 133 AGAMRRQQHTLR-----DPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRD 187
A A + HT + DP Q ++ L RLQ E + + + G L + L + +
Sbjct: 1435 AEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAE 1494
Query: 188 VRTACTL 194
V+ L
Sbjct: 1495 VKEKVVL 1501
Score = 29.6 bits (65), Expect = 8.8
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 4/93 (4%)
Query: 70 DSPQVRRKLELEAAVTRLRA----EIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRR 125
+ +V+ K+ L +V + EIQ L SLE R D + + + +
Sbjct: 1491 EKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFH 1550
Query: 126 ALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQ 158
+ +R + H L+ Q LQ + RRLQ
Sbjct: 1551 NSKSSKELDFLREENHKLQLERQNLQLETRRLQ 1583
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAM--------EQARQHTQDTQR 124
+++ ++E A++ L E ++ Q E M R+ EAQ E+ R+ + Q
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE 376
Query: 125 RALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
+ LR Q +R+Q+ LR +RLQ Q +RL D E +
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEER 415
Score = 34.7 bits (78), Expect = 0.27
Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
+L+ LR E++ L+ L+ + +A ++ +Q Q+ + +LR Q R
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE---MLREQEAQRVR 355
Query: 139 QQHTLRDPMQRLQNQLRRLQDMERKAK 165
+Q L + +RL+ Q + LQ+ + +
Sbjct: 356 EQERLCEQNERLREQQKTLQEQGERLR 382
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 73 QVRRKLELEAAVTRLRAE-IQELDQSLELMERDTEAQDTAMEQA---RQHTQDTQRRALL 128
Q +R E E + A+ ++E ++ E ER E Q T EQ R+ Q +++
Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394
Query: 129 LRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
LR + +++Q+ L D +RL + RLQ E +
Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 40.0 bits (92), Expect = 0.007
Identities = 82/356 (23%), Positives = 132/356 (37%), Gaps = 66/356 (18%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQ 132
Q++ + EL A LRA + Q LE + D EA+ E+ QH Q +++
Sbjct: 888 QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK------- 940
Query: 133 AGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTAC 192
++ +Q L+ QL + +K +++ L E ++L D C
Sbjct: 941 ----------MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN--C 988
Query: 193 TLR----------AQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGH 242
L A+F NL + K SL + H + ++ +E L
Sbjct: 989 KLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKH-----EAMITDLEERLRRE---- 1039
Query: 243 VLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQ---TLPSMVHLIQEGWR 299
E E E R L GD T++S A Q+ ++ L +Q
Sbjct: 1040 -----EKQRQELEKTRRKL-EGD---STDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090
Query: 300 TVGVLVSQRSTLLKERQVLTQRLQGLVE--EVERRVLGSSERQVLILGLRRCCLWTELKA 357
V +Q++ LK+ + L ++ L E E ER +E+Q LG L TEL+
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
Query: 358 LHDQSQELQDAAGHR-------------QLLLRELQAKQQRILHWRQLVEETQEQV 400
D + Q+ R + E Q ++ R H Q VEE EQ+
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH-SQAVEELAEQL 1205
Score = 31.2 bits (69), Expect = 3.0
Identities = 71/381 (18%), Positives = 149/381 (39%), Gaps = 61/381 (16%)
Query: 52 SQRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQEL-------DQSLELMERD 104
S+ KK+ L + + R + EL VT+L+ E+ + D + +D
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Query: 105 TEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQ-------RLQNQLRRL 157
A ++ ++ ++ Q+ R+ L L + + ++++ R+ ++ L+ Q+ L
Sbjct: 1303 FSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATL 1362
Query: 158 --QDMERKAKVDVTFGSLTSA-------ALGLEPVVLR-DVRTACTLRAQFLQNLLLPQA 207
Q + K K++ + G L +A LE + R + + A + + + L +
Sbjct: 1363 HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQEL 1422
Query: 208 KRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHLAAE---REAEIRSLCSG 264
+ H + ++ + LL A E AE RE E ++L
Sbjct: 1423 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482
Query: 265 DGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQG 324
L +A +Q + L E L+S + + K L + +
Sbjct: 1483 RAL-------EEAMEQKAELERLNKQFRTEMED------LMSSKDDVGKSVHELEKSKRA 1529
Query: 325 LVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQ 384
L ++VE + T+L+ L D+ Q +DA ++ L+ ++A+ +
Sbjct: 1530 LEQQVEE-------------------MKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
Query: 385 RILHWRQLVEETQEQVRLLIK 405
R L R E+++E+ + L++
Sbjct: 1571 RDLQGRD--EQSEEKKKQLVR 1589
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.007
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 51 HSQRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELME----RDTE 106
H ++ V+ + G L QV L + +QE ++ L E R+ E
Sbjct: 306 HLRQEVEGLEGKL-------QSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQE 358
Query: 107 AQDTAMEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
E+ R+ + Q + LR Q +R+Q+ LR +RLQ Q +RL D E +
Sbjct: 359 RLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEER 415
Score = 33.9 bits (76), Expect = 0.47
Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 73 QVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQ 132
Q + ++ E V R+R + + +Q+ L E+ Q+ E+ R+ Q +++ LR +
Sbjct: 340 QEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQG-ERLRKQEQRLRKQEERLRKE 398
Query: 133 AGAMRRQQHTLRDPMQRLQNQLRRLQDMERK 163
+++Q+ L D +RL + RLQ E +
Sbjct: 399 EERLQKQEKRLWDQEERLWKKEERLQKQEER 429
Score = 33.5 bits (75), Expect = 0.61
Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 79 ELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRR 138
+L+ LR E++ L+ L+ + +A ++ +Q Q+ + +LR Q R
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE---MLREQEVQRVR 355
Query: 139 QQHTLRDPMQRLQNQLRRLQDMERKAK 165
+Q L + +RL+ Q + LQ+ + +
Sbjct: 356 EQERLCEQNERLREQQKTLQEQGERLR 382
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 39.7 bits (91), Expect = 0.009
Identities = 127/602 (21%), Positives = 221/602 (36%), Gaps = 91/602 (15%)
Query: 75 RRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAME-----QARQHTQDTQRRALLL 129
+R +EL+ V L+ E+Q+ Q L+ D E ++ E Q + Q+T+ LL
Sbjct: 46 KRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELL 105
Query: 130 RAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTF-------------GSLTSA 176
+ ++ + ++ R+ L + E++ ++++ G
Sbjct: 106 ENKIQLLQEESRLAKNEAARMA----ALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKP 161
Query: 177 ALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSY-----------Q 225
E + RD R ++ Q L+ Q R H TS Q
Sbjct: 162 DQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQ 221
Query: 226 QWLSSVETLLTNHPPGHV-LAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSS 284
Q L+S ET +T LA L+ + EA + L E+ Q Q
Sbjct: 222 QKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDG 281
Query: 285 ------QTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSE 338
+TL S +E ++ V+ Q T+ K R++L Q G + E ++
Sbjct: 282 TIQNLKETLKSRERETEELYQ---VIEGQNDTMAKLREMLHQSQLGQLHSSEGT--SPAQ 336
Query: 339 RQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQE 398
+QV +L L+ ++L+ Q+LQ ++ R+L +Q + E+++
Sbjct: 337 QQVALLDLQSALFCSQLEI-----QKLQRVVRQKE---RQLADAKQCVQFVEAAAHESEQ 388
Query: 399 QVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHIL 458
Q K N + L + E+ Q+ A + +R E+ ++HL H L
Sbjct: 389 QKEASWKHNQELRKALQQLQEELQNKSQQ-----LRAWEAEKYNEIRTQEQNIQHLNHSL 443
Query: 459 ---------LGTLLRHRPGELKPLPT-------VLPSIHQLHPASPRGSSFIALSHKLGL 502
LL++R K L + IH A R A+ K
Sbjct: 444 SHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALER-----AIDEKFSA 498
Query: 503 PPGKASEL--LLPAAASLRQDLLLLQDQRSLWCWDLLHMKTSL-PPGLPTQEL---LQIQ 556
K EL L A DL L+D S + M++ L GL ++L Q
Sbjct: 499 LEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNL 558
Query: 557 ASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQ------PGQAALSEELCQ 610
+++ + + K E +++Q + + V D PGQ+ ++EELCQ
Sbjct: 559 QWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQ 618
Query: 611 GL 612
L
Sbjct: 619 RL 620
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 39.7 bits (91), Expect = 0.009
Identities = 127/602 (21%), Positives = 221/602 (36%), Gaps = 91/602 (15%)
Query: 75 RRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAME-----QARQHTQDTQRRALLL 129
+R +EL+ V L+ E+Q+ Q L+ D E ++ E Q + Q+T+ LL
Sbjct: 46 KRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELL 105
Query: 130 RAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTF-------------GSLTSA 176
+ ++ + ++ R+ L + E++ ++++ G
Sbjct: 106 ENKIQLLQEESRLAKNEAARMA----ALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKP 161
Query: 177 ALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSY-----------Q 225
E + RD R ++ Q L+ Q R H TS Q
Sbjct: 162 DQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQ 221
Query: 226 QWLSSVETLLTNHPPGHV-LAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSS 284
Q L+S ET +T LA L+ + EA + L E+ Q Q
Sbjct: 222 QKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDG 281
Query: 285 ------QTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSE 338
+TL S +E ++ V+ Q T+ K R++L Q G + E ++
Sbjct: 282 TIQNLKETLKSRERETEELYQ---VIEGQNDTMAKLREMLHQSQLGQLHSSEGT--SPAQ 336
Query: 339 RQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQE 398
+QV +L L+ ++L+ Q+LQ ++ R+L +Q + E+++
Sbjct: 337 QQVALLDLQSALFCSQLEI-----QKLQRVVRQKE---RQLADAKQCVQFVEAAAHESEQ 388
Query: 399 QVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHIL 458
Q K N + L + E+ Q+ A + +R E+ ++HL H L
Sbjct: 389 QKEASWKHNQELRKALQQLQEELQNKSQQ-----LRAWEAEKYNEIRTQEQNIQHLNHSL 443
Query: 459 ---------LGTLLRHRPGELKPLPT-------VLPSIHQLHPASPRGSSFIALSHKLGL 502
LL++R K L + IH A R A+ K
Sbjct: 444 SHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALER-----AIDEKFSA 498
Query: 503 PPGKASEL--LLPAAASLRQDLLLLQDQRSLWCWDLLHMKTSL-PPGLPTQEL---LQIQ 556
K EL L A DL L+D S + M++ L GL ++L Q
Sbjct: 499 LEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNL 558
Query: 557 ASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQ------PGQAALSEELCQ 610
+++ + + K E +++Q + + V D PGQ+ ++EELCQ
Sbjct: 559 QWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQ 618
Query: 611 GL 612
L
Sbjct: 619 RL 620
Score = 38.1 bits (87), Expect = 0.025
Identities = 77/310 (24%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 235 LTNHPPGHVLAALEHLAAEREAEIR---SLCSGDGLGD------TEISRPQAPDQSDSSQ 285
L + P G L EHL R R S+C D L + T +R + + SQ
Sbjct: 1834 LNSKPTGADLLE-EHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQ 1892
Query: 286 TLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILG 345
L S+ L E + +L+E +RLQ + V R S E + L
Sbjct: 1893 GLESIPQLCNE------------NRVLREDN---RRLQAQLSHVSRE--HSQETESL--- 1932
Query: 346 LRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIK 405
R L + L + +EL+ RQ LL +L+ KQQ +LH+R+ QE L +
Sbjct: 1933 --REALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRL-Q 1989
Query: 406 GNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRH 465
+ C ++ +Q + + +EA+ S++ L+ + H I L + L H
Sbjct: 1990 HKLVLLQQQCEEKQQLFESLQSE-LQIYEALYGNSKKGLKAYSLDACH--QIPLSSDLSH 2046
Query: 466 RPGELKPLPTVLPSIHQLHPASPRGSSFIALSHKLGLPPGKASELL--------LPAAAS 517
E++ L L S +G++ + L + L G L PA+
Sbjct: 2047 LVAEVRALRGQLEQ-------SIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTD 2099
Query: 518 LRQDLLLLQD 527
LLLQD
Sbjct: 2100 PGNKQLLLQD 2109
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 39.7 bits (91), Expect = 0.009
Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 77 KLELEAAVTRLRAEIQELDQSLELMERD-TEAQDTAMEQARQHTQDTQRRALLLRAQAGA 135
KL+LE VT LR+ +QEL+++L ++ TE + +R H + T+ R +L R Q
Sbjct: 134 KLQLEGQVTELRSRVQELERALATARQEHTELMEQYKGISRSHGEITEERDILSRQQGDH 193
Query: 136 MRR------QQHTLRDPMQRLQNQLRRLQD 159
+ R T+ + + + +L RL+D
Sbjct: 194 VARILELEDDIQTISEKVLTKEVELDRLRD 223
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 39.7 bits (91), Expect = 0.009
Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 77 KLELEAAVTRLRAEIQELDQSLELMERD-TEAQDTAMEQARQHTQDTQRRALLLRAQAGA 135
KL+LE VT LR+ +QEL+++L ++ TE + +R H + T+ R +L R Q
Sbjct: 167 KLQLEGQVTELRSRVQELERALATARQEHTELMEQYKGISRSHGEITEERDILSRQQGDH 226
Query: 136 MRR------QQHTLRDPMQRLQNQLRRLQD 159
+ R T+ + + + +L RL+D
Sbjct: 227 VARILELEDDIQTISEKVLTKEVELDRLRD 256
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 39.3 bits (90), Expect = 0.011
Identities = 83/336 (24%), Positives = 128/336 (38%), Gaps = 45/336 (13%)
Query: 312 LKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGH 371
L+ Q RLQG E+ R++L S + Q + W E K L + +G
Sbjct: 1254 LQSIQAQWTRLQGRSEQRRRQLLASLQLQEWKQDVAELMQWMEEKGL----MAAHEPSGA 1309
Query: 372 RQLLLREL---QAKQQRILHWRQLVEETQEQVRLLIK----GNSASKTRL--CRSPGEVL 422
R+ +L+ L +A + +L R+ VE Q+ R L+ G +TRL RS E L
Sbjct: 1310 RRNILQTLKRHEAAESELLATRRHVEALQQVGRELLSRRPCGQEDIQTRLQGLRSKWEAL 1369
Query: 423 ALVQRKVVPTFEAV--APQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSI 480
RK+ + + A Q +LLR L++ L L G L G+ L
Sbjct: 1370 ---NRKMTERGDELQQAGQQEQLLRQLQDAKEQLEQ-LEGALQSSETGQDLRSSQRLQKR 1425
Query: 481 HQLHPASPRG-----SSFIALSHKLGLPPGKASEL--------LLPAAASLRQDLLLLQD 527
HQ + R ++ +++H + P E LL ++R L
Sbjct: 1426 HQQLESESRTLAAKMAALASMAHGMAASPAILEETQKHLRRLELLQGHLAIRGLQLQASV 1485
Query: 528 QRSLWC----WDLLHMKTSLPPGLPTQ--ELLQIQASQEKQQKE-------NLGQALKRL 574
+ +C +L + +P G PT E L S ++ KE + GQ + L
Sbjct: 1486 ELHQFCHLSNMELSWVAEHMPHGSPTSYTECLNGAQSLHRKHKELQVEVKAHQGQVQRVL 1545
Query: 575 EKLLKQALERIPELQGIVGDWWEQPGQAALSEELCQ 610
A P+ Q IV E G A E C+
Sbjct: 1546 SSGRSLAASGHPQAQHIVEQCQELEGHWAELERACE 1581
Score = 35.0 bits (79), Expect = 0.21
Identities = 104/478 (21%), Positives = 170/478 (35%), Gaps = 105/478 (21%)
Query: 5 QEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIRGNLL 64
Q+++E+ W E+ V + ++ + L + + A + +H Q+ +++ LL
Sbjct: 2654 QDSQEVAAWLREKNLVALEEGLLDTAMLPAQLQKQQNFQAELDASMHQQQELQREGQRLL 2713
Query: 65 WYGHQDSPQVRRKLELEAAV---------------------TRLRAEIQELDQSLELMER 103
GH S ++ +LE A+ RLR ++EL+ LE +E
Sbjct: 2714 QGGHPASEAIQERLEELGALWGELQDNSQKKVAKLQKACEALRLRRSMEELENWLEPIEV 2773
Query: 104 DTEAQDT------------AMEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQ 151
+ A + R+A L QA A R+ H L Q ++
Sbjct: 2774 ELRAPTVGQALPGVGELLGTQRELEAAVDKKARQAEALLGQAQAFVREGHCL---AQDVE 2830
Query: 152 NQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGS 211
Q RRL + + + AL ++L+ R A A + L L A+
Sbjct: 2831 EQARRLLQRFKSLREPL---QERRTALEARSLLLKFFRDADEEMAWVQEKLPLAAAQ--- 2884
Query: 212 LPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHLAAEREAEIRSLCSGDGLGDTE 271
Y Q LS+V L H LE + EA R + G G +
Sbjct: 2885 -----------DYGQSLSAVRHLQEQH------QNLESEMSSHEALTR-VVLGTGYKLVQ 2926
Query: 272 ISRPQAPDQSDSSQTL-PSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVE 330
A + + Q L +M HL E ++R LL++ Q Q L L+E
Sbjct: 2927 AGHFAAHEVAARVQQLEKAMAHLRAE--------AARRRLLLQQAQEAQQFLTELLE--- 2975
Query: 331 RRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWR 390
GS W + S+++ +A Q LLR L+A ++ + +
Sbjct: 2976 ---AGS---------------WLAERGHVLDSEDMGHSAEATQALLRRLEATKRDLEAFS 3017
Query: 391 QLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLE 448
+E Q+ LL + SP KV+ +AV ELLR E
Sbjct: 3018 PRIERLQQTAALL------ESRKNPESP---------KVLAQLQAVREAHAELLRRAE 3060
Score = 33.1 bits (74), Expect = 0.80
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
Query: 287 LPSMVHLIQE-GWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILG 345
L S+V ++E G+ L Q TL Q L +++Q V + RR + RQ +
Sbjct: 1020 LQSVVVKVEEPGYAESQPLQGQVETL----QGLLKQVQEQVAQRARRQAETQARQSFLQE 1075
Query: 346 LRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQ 399
++ LW E +S+E+ Q LLRE Q + I W++ +++ Q
Sbjct: 1076 SQQLLLWAESVQAQLRSKEVSVDVASAQRLLREHQDLLEEIHLWQERLQQLDAQ 1129
>gi|154813191 IQ motif containing E isoform 1 [Homo sapiens]
Length = 695
Score = 39.3 bits (90), Expect = 0.011
Identities = 20/82 (24%), Positives = 42/82 (51%)
Query: 86 RLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRD 145
RLR +++L + ++ +D ++Q Q D ++ R R ++ LR+
Sbjct: 392 RLRGAVRDLKEERTALQEQLLQRDLEVKQLLQAKADLEKELECAREGEEERREREEVLRE 451
Query: 146 PMQRLQNQLRRLQDMERKAKVD 167
+Q L ++L+ LQ+M+++ K D
Sbjct: 452 EIQTLTSKLQELQEMKKEEKED 473
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,883,428
Number of Sequences: 37866
Number of extensions: 1175649
Number of successful extensions: 6822
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 5638
Number of HSP's gapped (non-prelim): 1436
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.