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Search of human proteins with 149193321
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149193321 G-rich RNA sequence binding factor 1 isoform 1
[Homo sapiens]
(480 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Hom... 963 0.0
gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Hom... 643 0.0
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap... 266 2e-71
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap... 266 2e-71
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap... 266 2e-71
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap... 266 2e-71
gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo sap... 266 2e-71
gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens] 266 2e-71
gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo sapi... 201 2e-51
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap... 201 2e-51
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi... 201 2e-51
gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens] 136 5e-32
gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens] 136 5e-32
gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens] 136 5e-32
gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens] 136 5e-32
gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens] 136 5e-32
gi|45935393 RNA binding motif protein 35B [Homo sapiens] 135 6e-32
gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a... 115 7e-26
gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b... 115 7e-26
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 95 1e-19
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 95 1e-19
gi|118722349 RNA binding motif protein 12B [Homo sapiens] 89 1e-17
gi|226497734 RNA binding motif protein 19 [Homo sapiens] 65 1e-10
gi|226497654 RNA binding motif protein 19 [Homo sapiens] 65 1e-10
gi|226497574 RNA binding motif protein 19 [Homo sapiens] 65 1e-10
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 50 3e-06
gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d ... 50 3e-06
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ... 49 1e-05
gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c ... 49 1e-05
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 47 5e-05
>gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Homo
sapiens]
Length = 480
Score = 963 bits (2490), Expect = 0.0
Identities = 480/480 (100%), Positives = 480/480 (100%)
Query: 1 MAGTRWVLGALLRGCGCNCSSCRRTGAACLPFYSAAGSIPSGVSGRRRLLLLLGAAAAAA 60
MAGTRWVLGALLRGCGCNCSSCRRTGAACLPFYSAAGSIPSGVSGRRRLLLLLGAAAAAA
Sbjct: 1 MAGTRWVLGALLRGCGCNCSSCRRTGAACLPFYSAAGSIPSGVSGRRRLLLLLGAAAAAA 60
Query: 61 SQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVPTRSYSQE 120
SQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVPTRSYSQE
Sbjct: 61 SQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVPTRSYSQE 120
Query: 121 SKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGEN 180
SKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGEN
Sbjct: 121 SKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGEN 180
Query: 181 GIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQ 240
GIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQ
Sbjct: 181 GIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQ 240
Query: 241 VKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEP 300
VKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEP
Sbjct: 241 VKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEP 300
Query: 301 EMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEH 360
EMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEH
Sbjct: 301 EMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEH 360
Query: 361 EVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINF 420
EVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINF
Sbjct: 361 EVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINF 420
Query: 421 FAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNSCPKGK 480
FAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNSCPKGK
Sbjct: 421 FAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNSCPKGK 480
>gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Homo
sapiens]
Length = 318
Score = 643 bits (1659), Expect = 0.0
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 163 MEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYV 222
MEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYV
Sbjct: 1 MEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYV 60
Query: 223 EVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVM 282
EVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVM
Sbjct: 61 EVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVM 120
Query: 283 DYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIA 342
DYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIA
Sbjct: 121 DYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIA 180
Query: 343 SFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHF 402
SFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHF
Sbjct: 181 SFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHF 240
Query: 403 VHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRS 462
VHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRS
Sbjct: 241 VHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRS 300
Query: 463 HVHHRYIELFLNSCPKGK 480
HVHHRYIELFLNSCPKGK
Sbjct: 301 HVHHRYIELFLNSCPKGK 318
Score = 89.7 bits (221), Expect = 5e-18
Identities = 68/228 (29%), Positives = 108/228 (47%), Gaps = 62/228 (27%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR-GDALIEMESEQDVQKA 209
++R +GLP+SC +D+++FF+ I + I F+++ G+R+ G+A ++ E + +A
Sbjct: 89 VVRLRGLPYSCNEKDIVDFFAGLNIVD----ITFVMDYRGRRKTGEAYVQFEEPEMANQA 144
Query: 210 LEKHRMYMGQRYVEVYEINNEDVDALM---KSLQVKSSPV---------------VNDGV 251
L KHR +G RY+E++ +V + K ++ S P VN+ +
Sbjct: 145 LLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDI 204
Query: 252 ------------------------------------VRLRGLPYSCNEKDIVDFFAGLNI 275
V +RGLP+ N +DI++FFA L
Sbjct: 205 QPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLKP 264
Query: 276 VDITFVMDYRGRRK-TGEAYVQFEEPEMANQALLKHREEIGNRYIEIF 322
V IT M+Y K TGEA V FE E A A+LK R + +RYIE+F
Sbjct: 265 VRIT--MEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 310
Score = 48.5 bits (114), Expect = 1e-05
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 25/136 (18%)
Query: 110 AAVPTRSYSQESKTTYLE-----DLPPPPEYEL---------APSKLEEEVD-----DVF 150
A+ PT Y E + + E D+ P +E P KL E D +
Sbjct: 180 ASFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLH 239
Query: 151 LIRAQGLPWSCTMEDVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
+ +GLP+ +D++NFF+ + +R I + GK G+A + E+ +D A
Sbjct: 240 FVHMRGLPFQANAQDIINFFAPLKPVR-----ITMEYSSSGKATGEADVHFETHEDAVAA 294
Query: 210 LEKHRMYMGQRYVEVY 225
+ K R ++ RY+E++
Sbjct: 295 MLKDRSHVHHRYIELF 310
>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 266 bits (681), Expect = 2e-71
Identities = 151/363 (41%), Positives = 215/363 (59%), Gaps = 31/363 (8%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC++EDV NF SDC I +G G+HF+ R+G++ G+A +E+
Sbjct: 3 LGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELG 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE DV+ AL+K R MG RY+EV++ + ++D ++K S+ NDG VRLRGLP+ C
Sbjct: 63 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
+++IV FF+GL IV IT +D G + TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 TKEEIVQFFSGLEIVPNGITLPVDPEG-KITGEAFVQFASQELAEKALGKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRT-------------------------HVGSYKGKKIASFPTAKYITEPE 354
E+F S + EVR+ ++G K + Y T
Sbjct: 182 EVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYST-GY 240
Query: 355 MVFEEHEVNEDIQPMTA--FESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQA 412
+EE+ D T F + L + ++ +++ H VHMRGLP++A
Sbjct: 241 GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA 300
Query: 413 NAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
DI NFF+PL PVR+ +E G+ TGEADV F THE+AVAAM KDR+++ HRYIELF
Sbjct: 301 TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF 360
Query: 473 LNS 475
LNS
Sbjct: 361 LNS 363
>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 266 bits (681), Expect = 2e-71
Identities = 151/363 (41%), Positives = 215/363 (59%), Gaps = 31/363 (8%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC++EDV NF SDC I +G G+HF+ R+G++ G+A +E+
Sbjct: 3 LGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELG 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE DV+ AL+K R MG RY+EV++ + ++D ++K S+ NDG VRLRGLP+ C
Sbjct: 63 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
+++IV FF+GL IV IT +D G + TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 TKEEIVQFFSGLEIVPNGITLPVDPEG-KITGEAFVQFASQELAEKALGKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRT-------------------------HVGSYKGKKIASFPTAKYITEPE 354
E+F S + EVR+ ++G K + Y T
Sbjct: 182 EVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYST-GY 240
Query: 355 MVFEEHEVNEDIQPMTA--FESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQA 412
+EE+ D T F + L + ++ +++ H VHMRGLP++A
Sbjct: 241 GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA 300
Query: 413 NAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
DI NFF+PL PVR+ +E G+ TGEADV F THE+AVAAM KDR+++ HRYIELF
Sbjct: 301 TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF 360
Query: 473 LNS 475
LNS
Sbjct: 361 LNS 363
>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 266 bits (681), Expect = 2e-71
Identities = 151/363 (41%), Positives = 215/363 (59%), Gaps = 31/363 (8%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC++EDV NF SDC I +G G+HF+ R+G++ G+A +E+
Sbjct: 3 LGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELG 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE DV+ AL+K R MG RY+EV++ + ++D ++K S+ NDG VRLRGLP+ C
Sbjct: 63 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
+++IV FF+GL IV IT +D G + TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 TKEEIVQFFSGLEIVPNGITLPVDPEG-KITGEAFVQFASQELAEKALGKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRT-------------------------HVGSYKGKKIASFPTAKYITEPE 354
E+F S + EVR+ ++G K + Y T
Sbjct: 182 EVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYST-GY 240
Query: 355 MVFEEHEVNEDIQPMTA--FESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQA 412
+EE+ D T F + L + ++ +++ H VHMRGLP++A
Sbjct: 241 GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA 300
Query: 413 NAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
DI NFF+PL PVR+ +E G+ TGEADV F THE+AVAAM KDR+++ HRYIELF
Sbjct: 301 TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF 360
Query: 473 LNS 475
LNS
Sbjct: 361 LNS 363
>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 266 bits (681), Expect = 2e-71
Identities = 151/363 (41%), Positives = 215/363 (59%), Gaps = 31/363 (8%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC++EDV NF SDC I +G G+HF+ R+G++ G+A +E+
Sbjct: 3 LGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELG 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE DV+ AL+K R MG RY+EV++ + ++D ++K S+ NDG VRLRGLP+ C
Sbjct: 63 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
+++IV FF+GL IV IT +D G + TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 TKEEIVQFFSGLEIVPNGITLPVDPEG-KITGEAFVQFASQELAEKALGKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRT-------------------------HVGSYKGKKIASFPTAKYITEPE 354
E+F S + EVR+ ++G K + Y T
Sbjct: 182 EVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYST-GY 240
Query: 355 MVFEEHEVNEDIQPMTA--FESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQA 412
+EE+ D T F + L + ++ +++ H VHMRGLP++A
Sbjct: 241 GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA 300
Query: 413 NAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
DI NFF+PL PVR+ +E G+ TGEADV F THE+AVAAM KDR+++ HRYIELF
Sbjct: 301 TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF 360
Query: 473 LNS 475
LNS
Sbjct: 361 LNS 363
>gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 266 bits (681), Expect = 2e-71
Identities = 151/363 (41%), Positives = 215/363 (59%), Gaps = 31/363 (8%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC++EDV NF SDC I +G G+HF+ R+G++ G+A +E+
Sbjct: 3 LGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELG 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE DV+ AL+K R MG RY+EV++ + ++D ++K S+ NDG VRLRGLP+ C
Sbjct: 63 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
+++IV FF+GL IV IT +D G + TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 TKEEIVQFFSGLEIVPNGITLPVDPEG-KITGEAFVQFASQELAEKALGKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRT-------------------------HVGSYKGKKIASFPTAKYITEPE 354
E+F S + EVR+ ++G K + Y T
Sbjct: 182 EVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYST-GY 240
Query: 355 MVFEEHEVNEDIQPMTA--FESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQA 412
+EE+ D T F + L + ++ +++ H VHMRGLP++A
Sbjct: 241 GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA 300
Query: 413 NAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
DI NFF+PL PVR+ +E G+ TGEADV F THE+AVAAM KDR+++ HRYIELF
Sbjct: 301 TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF 360
Query: 473 LNS 475
LNS
Sbjct: 361 LNS 363
>gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens]
Length = 415
Score = 266 bits (681), Expect = 2e-71
Identities = 151/363 (41%), Positives = 215/363 (59%), Gaps = 31/363 (8%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC++EDV NF SDC I +G G+HF+ R+G++ G+A +E+
Sbjct: 3 LGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELG 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE DV+ AL+K R MG RY+EV++ + ++D ++K S+ NDG VRLRGLP+ C
Sbjct: 63 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
+++IV FF+GL IV IT +D G + TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 TKEEIVQFFSGLEIVPNGITLPVDPEG-KITGEAFVQFASQELAEKALGKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRT-------------------------HVGSYKGKKIASFPTAKYITEPE 354
E+F S + EVR+ ++G K + Y T
Sbjct: 182 EVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYST-GY 240
Query: 355 MVFEEHEVNEDIQPMTA--FESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQA 412
+EE+ D T F + L + ++ +++ H VHMRGLP++A
Sbjct: 241 GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA 300
Query: 413 NAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
DI NFF+PL PVR+ +E G+ TGEADV F THE+AVAAM KDR+++ HRYIELF
Sbjct: 301 TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF 360
Query: 473 LNS 475
LNS
Sbjct: 361 LNS 363
>gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo
sapiens]
Length = 449
Score = 201 bits (510), Expect = 2e-51
Identities = 99/193 (51%), Positives = 138/193 (71%), Gaps = 3/193 (1%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC+ ++V FFSDC+I+NG GI F+ R+G+ G+A +E+E
Sbjct: 3 LGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELE 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE +V+ AL+K R MG RYVEV++ NN ++D ++K S NDG VRLRGLP+ C
Sbjct: 63 SEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
++++IV FF+GL IV IT +D++G R TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 SKEEIVQFFSGLEIVPNGITLPVDFQG-RSTGEAFVQFASQEIAEKALKKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRTH 332
EIF S R EVRTH
Sbjct: 182 EIFKSSRAEVRTH 194
Score = 107 bits (266), Expect = 3e-23
Identities = 48/75 (64%), Positives = 59/75 (78%)
Query: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
H VHMRGLP++A DI NFF+PL PVR+ +E G+ TGEADV F THEDAVAAM KD
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKD 348
Query: 461 RSHVHHRYIELFLNS 475
++++ HRY+ELFLNS
Sbjct: 349 KANMQHRYVELFLNS 363
Score = 92.8 bits (229), Expect = 6e-19
Identities = 69/231 (29%), Positives = 106/231 (45%), Gaps = 61/231 (26%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVD----ITFVMDYRGRRKTGEAYVQFEEPEMANQA 306
VV++RGLP+SC+ ++ FF+ I + I F+ GR +GEA+V+ E + A
Sbjct: 12 VVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGR-PSGEAFVELESEDEVKLA 70
Query: 307 LLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDI 366
L K RE +G+RY+E+F S E + V + N
Sbjct: 71 LKKDRETMGHRYVEVFKSNN------------------------VEMDWVLKHTGPNS-- 104
Query: 367 QPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLK- 425
P+ A+ G FV +RGLPF + ++I+ FF+ L+
Sbjct: 105 ----------------------PDTANDG------FVRLRGLPFGCSKEEIVQFFSGLEI 136
Query: 426 -PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNS 475
P IT+ G++TGEA V F + E A A+ K + + HRYIE+F +S
Sbjct: 137 VPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSS 187
Score = 52.4 bits (124), Expect = 9e-07
Identities = 30/71 (42%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
V +RGLPY E DI +FF+ LN V + + G R TGEA V+F E A A+ K +
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDG-RVTGEADVEFATHEDAVAAMSKDK 349
Query: 312 EEIGNRYIEIF 322
+ +RY+E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 46.2 bits (108), Expect = 7e-05
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
+ +GLP+ T D+ NFFS +R +H + DG+ G+A +E + +D A+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPVR-----VHIEIGPDGRVTGEADVEFATHEDAVAAM 345
Query: 211 EKHRMYMGQRYVEVY 225
K + M RYVE++
Sbjct: 346 SKDKANMQHRYVELF 360
>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 201 bits (510), Expect = 2e-51
Identities = 97/193 (50%), Positives = 141/193 (73%), Gaps = 3/193 (1%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC+ ++V+ FFSDC+I+NG +GI F+ R+G+ G+A +E+E
Sbjct: 3 LSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELE 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE++V+ AL+K R MG RYVEV++ N+ ++D ++K S NDG VRLRGLP+ C
Sbjct: 63 SEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
++++IV FF+GL IV +T +D++G R TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 SKEEIVQFFSGLEIVPNGMTLPVDFQG-RSTGEAFVQFASQEIAEKALKKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRTH 332
EIF S R EVRTH
Sbjct: 182 EIFKSSRAEVRTH 194
Score = 106 bits (264), Expect = 5e-23
Identities = 47/75 (62%), Positives = 59/75 (78%)
Query: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
H VHMRGLP++A DI NFF+PL P+R+ +E G+ TGEADV F THEDAVAAM KD
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKD 348
Query: 461 RSHVHHRYIELFLNS 475
++++ HRY+ELFLNS
Sbjct: 349 KANMQHRYVELFLNS 363
Score = 93.6 bits (231), Expect = 4e-19
Identities = 69/231 (29%), Positives = 107/231 (46%), Gaps = 61/231 (26%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVD----ITFVMDYRGRRKTGEAYVQFEEPEMANQA 306
VV++RGLP+SC+ +++ FF+ I + I F+ GR +GEA+V+ E E A
Sbjct: 12 VVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGR-PSGEAFVELESEEEVKLA 70
Query: 307 LLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDI 366
L K RE +G+RY+E+F S E + V + N
Sbjct: 71 LKKDRETMGHRYVEVFKSNS------------------------VEMDWVLKHTGPNS-- 104
Query: 367 QPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLK- 425
P+ A+ G FV +RGLPF + ++I+ FF+ L+
Sbjct: 105 ----------------------PDTANDG------FVRLRGLPFGCSKEEIVQFFSGLEI 136
Query: 426 -PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNS 475
P +T+ G++TGEA V F + E A A+ K + + HRYIE+F +S
Sbjct: 137 VPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSS 187
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
V +RGLPY E DI +FF+ LN + + + G R TGEA V+F E A A+ K +
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDG-RVTGEADVEFATHEDAVAAMAKDK 349
Query: 312 EEIGNRYIEIF 322
+ +RY+E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 46.2 bits (108), Expect = 7e-05
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
+ +GLP+ T D+ NFFS +H + DG+ G+A +E + +D A+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMR----VHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 212 KHRMYMGQRYVEVY 225
K + M RYVE++
Sbjct: 347 KDKANMQHRYVELF 360
>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 201 bits (510), Expect = 2e-51
Identities = 97/193 (50%), Positives = 141/193 (73%), Gaps = 3/193 (1%)
Query: 142 LEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEME 201
L E + F+++ +GLPWSC+ ++V+ FFSDC+I+NG +GI F+ R+G+ G+A +E+E
Sbjct: 3 LSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELE 62
Query: 202 SEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSC 261
SE++V+ AL+K R MG RYVEV++ N+ ++D ++K S NDG VRLRGLP+ C
Sbjct: 63 SEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGC 122
Query: 262 NEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYI 319
++++IV FF+GL IV +T +D++G R TGEA+VQF E+A +AL KH+E IG+RYI
Sbjct: 123 SKEEIVQFFSGLEIVPNGMTLPVDFQG-RSTGEAFVQFASQEIAEKALKKHKERIGHRYI 181
Query: 320 EIFPSRRNEVRTH 332
EIF S R EVRTH
Sbjct: 182 EIFKSSRAEVRTH 194
Score = 106 bits (264), Expect = 5e-23
Identities = 47/75 (62%), Positives = 59/75 (78%)
Query: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
H VHMRGLP++A DI NFF+PL P+R+ +E G+ TGEADV F THEDAVAAM KD
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKD 348
Query: 461 RSHVHHRYIELFLNS 475
++++ HRY+ELFLNS
Sbjct: 349 KANMQHRYVELFLNS 363
Score = 93.6 bits (231), Expect = 4e-19
Identities = 69/231 (29%), Positives = 107/231 (46%), Gaps = 61/231 (26%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVD----ITFVMDYRGRRKTGEAYVQFEEPEMANQA 306
VV++RGLP+SC+ +++ FF+ I + I F+ GR +GEA+V+ E E A
Sbjct: 12 VVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGR-PSGEAFVELESEEEVKLA 70
Query: 307 LLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDI 366
L K RE +G+RY+E+F S E + V + N
Sbjct: 71 LKKDRETMGHRYVEVFKSNS------------------------VEMDWVLKHTGPNS-- 104
Query: 367 QPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLK- 425
P+ A+ G FV +RGLPF + ++I+ FF+ L+
Sbjct: 105 ----------------------PDTANDG------FVRLRGLPFGCSKEEIVQFFSGLEI 136
Query: 426 -PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNS 475
P +T+ G++TGEA V F + E A A+ K + + HRYIE+F +S
Sbjct: 137 VPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSS 187
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
V +RGLPY E DI +FF+ LN + + + G R TGEA V+F E A A+ K +
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDG-RVTGEADVEFATHEDAVAAMAKDK 349
Query: 312 EEIGNRYIEIF 322
+ +RY+E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 46.2 bits (108), Expect = 7e-05
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
+ +GLP+ T D+ NFFS +H + DG+ G+A +E + +D A+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMR----VHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 212 KHRMYMGQRYVEVY 225
K + M RYVE++
Sbjct: 347 KDKANMQHRYVELF 360
>gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens]
Length = 604
Score = 136 bits (342), Expect = 5e-32
Identities = 102/356 (28%), Positives = 167/356 (46%), Gaps = 60/356 (16%)
Query: 134 EYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR 193
++E E +DD ++RA+GLPW + +D+ FF I G G LN G+R
Sbjct: 209 KFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKG--GAALCLNAQGRRN 266
Query: 194 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVV------ 247
G+AL+ SE+ AL++H+ +MG RY+EVY+ ED +K S+ V
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGED---FLKIAGGTSNEVAQFLSKE 323
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIV-----DITFVMDYRGRRKTGEAYVQFEEPEM 302
N +VR+RGLP++ +++V FF + I FV Y R TG+A+V F E
Sbjct: 324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFV-TYPDGRPTGDAFVLFACEEY 382
Query: 303 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEV 362
A AL KH++ +G RYIE+F S EV+ + + + PT I
Sbjct: 383 AQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIP----------- 431
Query: 363 NEDIQPMTAFESEKEIELPKE-VPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
LP++ VP T+ + +RGLP+ A +DI++F
Sbjct: 432 ----------------VLPQQFVP----------PTNVRDCIRLRGLPYAATIEDILDFL 465
Query: 422 ----APLKPVRITMEYSSSGKATGEADVHFETHEDA-VAAMLKDRSHVHHRYIELF 472
++ + M + G+ +G+A + ++ + A +AA + ++ RY+E+F
Sbjct: 466 GEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVF 521
Score = 97.1 bits (240), Expect = 3e-20
Identities = 58/203 (28%), Positives = 107/203 (52%), Gaps = 25/203 (12%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSD-CRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
++R +GLP++ T E+V+ FF C I G+ GI F+ DG+ GDA + E+ Q A
Sbjct: 327 IVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNA 386
Query: 210 LEKHRMYMGQRYVEVYEINNEDVDALMKS------LQVKSSPVVN------------DGV 251
L KH+ +G+RY+E++ +V ++ + + + P++
Sbjct: 387 LRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDC 446
Query: 252 VRLRGLPYSCNEKDIVDFFA----GLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQAL 307
+RLRGLPY+ +DI+DF + + V++++GR +G+A++Q + + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGR-PSGDAFIQMKSADRAFMAA 505
Query: 308 LK-HREEIGNRYIEIFPSRRNEV 329
K H++ + +RY+E+F E+
Sbjct: 506 QKCHKKNMKDRYVEVFQCSAEEM 528
Score = 69.7 bits (169), Expect = 6e-12
Identities = 36/109 (33%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
Query: 129 LPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNR 188
LP PP + P + + IR +GLP++ T+ED+L+F + +G+H +LN
Sbjct: 424 LPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNH 483
Query: 189 DGKRRGDALIEMESEQDVQKALEK-HRMYMGQRYVEVYEINNEDVDALM 236
G+ GDA I+M+S A +K H+ M RYVEV++ + E+++ ++
Sbjct: 484 QGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532
>gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens]
Length = 659
Score = 136 bits (342), Expect = 5e-32
Identities = 102/356 (28%), Positives = 167/356 (46%), Gaps = 60/356 (16%)
Query: 134 EYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR 193
++E E +DD ++RA+GLPW + +D+ FF I G G LN G+R
Sbjct: 209 KFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKG--GAALCLNAQGRRN 266
Query: 194 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVV------ 247
G+AL+ SE+ AL++H+ +MG RY+EVY+ ED +K S+ V
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGED---FLKIAGGTSNEVAQFLSKE 323
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIV-----DITFVMDYRGRRKTGEAYVQFEEPEM 302
N +VR+RGLP++ +++V FF + I FV Y R TG+A+V F E
Sbjct: 324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFV-TYPDGRPTGDAFVLFACEEY 382
Query: 303 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEV 362
A AL KH++ +G RYIE+F S EV+ + + + PT I
Sbjct: 383 AQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIP----------- 431
Query: 363 NEDIQPMTAFESEKEIELPKE-VPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
LP++ VP T+ + +RGLP+ A +DI++F
Sbjct: 432 ----------------VLPQQFVP----------PTNVRDCIRLRGLPYAATIEDILDFL 465
Query: 422 ----APLKPVRITMEYSSSGKATGEADVHFETHEDA-VAAMLKDRSHVHHRYIELF 472
++ + M + G+ +G+A + ++ + A +AA + ++ RY+E+F
Sbjct: 466 GEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVF 521
Score = 98.6 bits (244), Expect = 1e-20
Identities = 82/328 (25%), Positives = 144/328 (43%), Gaps = 62/328 (18%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSD-CRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
++R +GLP++ T E+V+ FF C I G+ GI F+ DG+ GDA + E+ Q A
Sbjct: 327 IVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNA 386
Query: 210 LEKHRMYMGQRYVEVYEINNEDVDALMKS------LQVKSSPVVN------------DGV 251
L KH+ +G+RY+E++ +V ++ + + + P++
Sbjct: 387 LRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDC 446
Query: 252 VRLRGLPYSCNEKDIVDFFA----GLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQAL 307
+RLRGLPY+ +DI+DF + + V++++GR +G+A++Q + + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGR-PSGDAFIQMKSADRAFMAA 505
Query: 308 LK-HREEIGNRYIEIFPSRRNEVR-THVGSYKGKK------------------IASFPTA 347
K H++ + +RY+E+F E+ +G + A PT
Sbjct: 506 QKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCLSPPSYTFPAPAAVIPTE 565
Query: 348 KYITEPEMVFEEHEVNEDIQPMTAF---------ESEKEIELPKEVPEKL---PEAADFG 395
I +P ++ +QP TA+ P P L P AA+
Sbjct: 566 AAIYQPSVILNPRA----LQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLS 621
Query: 396 TTSSL--HFVHMRGLPFQANAQDIINFF 421
V M+GL + ++I+NFF
Sbjct: 622 GVPPQPGTVVRMQGLAYNTGVKEILNFF 649
Score = 69.7 bits (169), Expect = 6e-12
Identities = 36/109 (33%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
Query: 129 LPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNR 188
LP PP + P + + IR +GLP++ T+ED+L+F + +G+H +LN
Sbjct: 424 LPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNH 483
Query: 189 DGKRRGDALIEMESEQDVQKALEK-HRMYMGQRYVEVYEINNEDVDALM 236
G+ GDA I+M+S A +K H+ M RYVEV++ + E+++ ++
Sbjct: 484 QGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532
>gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens]
Length = 608
Score = 136 bits (342), Expect = 5e-32
Identities = 102/356 (28%), Positives = 167/356 (46%), Gaps = 60/356 (16%)
Query: 134 EYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR 193
++E E +DD ++RA+GLPW + +D+ FF I G G LN G+R
Sbjct: 209 KFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKG--GAALCLNAQGRRN 266
Query: 194 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVV------ 247
G+AL+ SE+ AL++H+ +MG RY+EVY+ ED +K S+ V
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGED---FLKIAGGTSNEVAQFLSKE 323
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIV-----DITFVMDYRGRRKTGEAYVQFEEPEM 302
N +VR+RGLP++ +++V FF + I FV Y R TG+A+V F E
Sbjct: 324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFV-TYPDGRPTGDAFVLFACEEY 382
Query: 303 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEV 362
A AL KH++ +G RYIE+F S EV+ + + + PT I
Sbjct: 383 AQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIP----------- 431
Query: 363 NEDIQPMTAFESEKEIELPKE-VPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
LP++ VP T+ + +RGLP+ A +DI++F
Sbjct: 432 ----------------VLPQQFVP----------PTNVRDCIRLRGLPYAATIEDILDFL 465
Query: 422 ----APLKPVRITMEYSSSGKATGEADVHFETHEDA-VAAMLKDRSHVHHRYIELF 472
++ + M + G+ +G+A + ++ + A +AA + ++ RY+E+F
Sbjct: 466 GEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVF 521
Score = 97.1 bits (240), Expect = 3e-20
Identities = 58/203 (28%), Positives = 107/203 (52%), Gaps = 25/203 (12%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSD-CRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
++R +GLP++ T E+V+ FF C I G+ GI F+ DG+ GDA + E+ Q A
Sbjct: 327 IVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNA 386
Query: 210 LEKHRMYMGQRYVEVYEINNEDVDALMKS------LQVKSSPVVN------------DGV 251
L KH+ +G+RY+E++ +V ++ + + + P++
Sbjct: 387 LRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDC 446
Query: 252 VRLRGLPYSCNEKDIVDFFA----GLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQAL 307
+RLRGLPY+ +DI+DF + + V++++GR +G+A++Q + + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGR-PSGDAFIQMKSADRAFMAA 505
Query: 308 LK-HREEIGNRYIEIFPSRRNEV 329
K H++ + +RY+E+F E+
Sbjct: 506 QKCHKKNMKDRYVEVFQCSAEEM 528
Score = 69.7 bits (169), Expect = 6e-12
Identities = 36/109 (33%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
Query: 129 LPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNR 188
LP PP + P + + IR +GLP++ T+ED+L+F + +G+H +LN
Sbjct: 424 LPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNH 483
Query: 189 DGKRRGDALIEMESEQDVQKALEK-HRMYMGQRYVEVYEINNEDVDALM 236
G+ GDA I+M+S A +K H+ M RYVEV++ + E+++ ++
Sbjct: 484 QGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532
>gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens]
Length = 677
Score = 136 bits (342), Expect = 5e-32
Identities = 102/356 (28%), Positives = 167/356 (46%), Gaps = 60/356 (16%)
Query: 134 EYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR 193
++E E +DD ++RA+GLPW + +D+ FF I G G LN G+R
Sbjct: 209 KFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKG--GAALCLNAQGRRN 266
Query: 194 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVV------ 247
G+AL+ SE+ AL++H+ +MG RY+EVY+ ED +K S+ V
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGED---FLKIAGGTSNEVAQFLSKE 323
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIV-----DITFVMDYRGRRKTGEAYVQFEEPEM 302
N +VR+RGLP++ +++V FF + I FV Y R TG+A+V F E
Sbjct: 324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFV-TYPDGRPTGDAFVLFACEEY 382
Query: 303 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEV 362
A AL KH++ +G RYIE+F S EV+ + + + PT I
Sbjct: 383 AQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIP----------- 431
Query: 363 NEDIQPMTAFESEKEIELPKE-VPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
LP++ VP T+ + +RGLP+ A +DI++F
Sbjct: 432 ----------------VLPQQFVP----------PTNVRDCIRLRGLPYAATIEDILDFL 465
Query: 422 ----APLKPVRITMEYSSSGKATGEADVHFETHEDA-VAAMLKDRSHVHHRYIELF 472
++ + M + G+ +G+A + ++ + A +AA + ++ RY+E+F
Sbjct: 466 GEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVF 521
Score = 98.6 bits (244), Expect = 1e-20
Identities = 82/328 (25%), Positives = 144/328 (43%), Gaps = 62/328 (18%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSD-CRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
++R +GLP++ T E+V+ FF C I G+ GI F+ DG+ GDA + E+ Q A
Sbjct: 327 IVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNA 386
Query: 210 LEKHRMYMGQRYVEVYEINNEDVDALMKS------LQVKSSPVVN------------DGV 251
L KH+ +G+RY+E++ +V ++ + + + P++
Sbjct: 387 LRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDC 446
Query: 252 VRLRGLPYSCNEKDIVDFFA----GLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQAL 307
+RLRGLPY+ +DI+DF + + V++++GR +G+A++Q + + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGR-PSGDAFIQMKSADRAFMAA 505
Query: 308 LK-HREEIGNRYIEIFPSRRNEVR-THVGSYKGKK------------------IASFPTA 347
K H++ + +RY+E+F E+ +G + A PT
Sbjct: 506 QKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCLSPPSYTFPAPAAVIPTE 565
Query: 348 KYITEPEMVFEEHEVNEDIQPMTAF---------ESEKEIELPKEVPEKL---PEAADFG 395
I +P ++ +QP TA+ P P L P AA+
Sbjct: 566 AAIYQPSVILNPRA----LQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLS 621
Query: 396 TTSSL--HFVHMRGLPFQANAQDIINFF 421
V M+GL + ++I+NFF
Sbjct: 622 GVPPQPGTVVRMQGLAYNTGVKEILNFF 649
Score = 69.7 bits (169), Expect = 6e-12
Identities = 36/109 (33%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
Query: 129 LPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNR 188
LP PP + P + + IR +GLP++ T+ED+L+F + +G+H +LN
Sbjct: 424 LPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNH 483
Query: 189 DGKRRGDALIEMESEQDVQKALEK-HRMYMGQRYVEVYEINNEDVDALM 236
G+ GDA I+M+S A +K H+ M RYVEV++ + E+++ ++
Sbjct: 484 QGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532
>gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens]
Length = 681
Score = 136 bits (342), Expect = 5e-32
Identities = 102/356 (28%), Positives = 167/356 (46%), Gaps = 60/356 (16%)
Query: 134 EYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR 193
++E E +DD ++RA+GLPW + +D+ FF I G G LN G+R
Sbjct: 209 KFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKG--GAALCLNAQGRRN 266
Query: 194 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVV------ 247
G+AL+ SE+ AL++H+ +MG RY+EVY+ ED +K S+ V
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGED---FLKIAGGTSNEVAQFLSKE 323
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIV-----DITFVMDYRGRRKTGEAYVQFEEPEM 302
N +VR+RGLP++ +++V FF + I FV Y R TG+A+V F E
Sbjct: 324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFV-TYPDGRPTGDAFVLFACEEY 382
Query: 303 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEV 362
A AL KH++ +G RYIE+F S EV+ + + + PT I
Sbjct: 383 AQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIP----------- 431
Query: 363 NEDIQPMTAFESEKEIELPKE-VPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
LP++ VP T+ + +RGLP+ A +DI++F
Sbjct: 432 ----------------VLPQQFVP----------PTNVRDCIRLRGLPYAATIEDILDFL 465
Query: 422 ----APLKPVRITMEYSSSGKATGEADVHFETHEDA-VAAMLKDRSHVHHRYIELF 472
++ + M + G+ +G+A + ++ + A +AA + ++ RY+E+F
Sbjct: 466 GEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVF 521
Score = 97.1 bits (240), Expect = 3e-20
Identities = 58/203 (28%), Positives = 107/203 (52%), Gaps = 25/203 (12%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSD-CRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
++R +GLP++ T E+V+ FF C I G+ GI F+ DG+ GDA + E+ Q A
Sbjct: 327 IVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNA 386
Query: 210 LEKHRMYMGQRYVEVYEINNEDVDALMKS------LQVKSSPVVN------------DGV 251
L KH+ +G+RY+E++ +V ++ + + + P++
Sbjct: 387 LRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDC 446
Query: 252 VRLRGLPYSCNEKDIVDFFA----GLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQAL 307
+RLRGLPY+ +DI+DF + + V++++GR +G+A++Q + + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGR-PSGDAFIQMKSADRAFMAA 505
Query: 308 LK-HREEIGNRYIEIFPSRRNEV 329
K H++ + +RY+E+F E+
Sbjct: 506 QKCHKKNMKDRYVEVFQCSAEEM 528
Score = 69.7 bits (169), Expect = 6e-12
Identities = 36/109 (33%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
Query: 129 LPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNR 188
LP PP + P + + IR +GLP++ T+ED+L+F + +G+H +LN
Sbjct: 424 LPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNH 483
Query: 189 DGKRRGDALIEMESEQDVQKALEK-HRMYMGQRYVEVYEINNEDVDALM 236
G+ GDA I+M+S A +K H+ M RYVEV++ + E+++ ++
Sbjct: 484 QGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532
>gi|45935393 RNA binding motif protein 35B [Homo sapiens]
Length = 717
Score = 135 bits (341), Expect = 6e-32
Identities = 106/351 (30%), Positives = 161/351 (45%), Gaps = 54/351 (15%)
Query: 134 EYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRR 193
+YE P + VD ++RA+GLPW + +DV FF + G G+ LN G+R
Sbjct: 231 KYETGPCSKADVVDSETVVRARGLPWQSSDQDVARFFKGLNVARG--GVALCLNAQGRRN 288
Query: 194 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALM--KSLQVKSSPVVNDGV 251
G+ALI + AL++H+ +MG RY+EVY+ E+ + SL+V D V
Sbjct: 289 GEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQV 348
Query: 252 V-RLRGLPYSCNEKDIVDFFAGLNIVD-----ITFVMDYRGRRKTGEAYVQFEEPEMANQ 305
+ RLRGLP+S D++ F V + FV GR TG+A+ F E+A
Sbjct: 349 ILRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGR-PTGDAFALFACEELAQA 407
Query: 306 ALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNED 365
AL +H+ +G RYIE+F S EV+ + Y AS P +T P +
Sbjct: 408 ALRRHKGMLGKRYIELFRSTAAEVQQVLNRY-----ASGPLLPTLTAPLL---------- 452
Query: 366 IQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF---- 421
P P A G V +RGLP+ A +DI++F
Sbjct: 453 -------------------PIPFPLAPGTGRDC----VRLRGLPYTATIEDILSFLGEAA 489
Query: 422 APLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHV-HHRYIEL 471
A ++P + M + G+ +G+A + + E A+AA + V RY+E+
Sbjct: 490 ADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQRCHKKVMKERYVEV 540
Score = 91.3 bits (225), Expect = 2e-18
Identities = 63/225 (28%), Positives = 108/225 (48%), Gaps = 24/225 (10%)
Query: 147 DDVFLIRAQGLPWSCTMEDVLNFFS-DCRIRNGENGIHFLLNRDGKRRGDALIEMESEQD 205
+D ++R +GLP+S DVL F +C + G G+ F+ + DG+ GDA E+
Sbjct: 345 EDQVILRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEEL 404
Query: 206 VQKALEKHRMYMGQRYVEVYEINNEDVDALMKS----------------LQVKSSPVVND 249
Q AL +H+ +G+RY+E++ +V ++ + +P
Sbjct: 405 AQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASGPLLPTLTAPLLPIPFPLAPGTGR 464
Query: 250 GVVRLRGLPYSCNEKDIVDFF----AGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQ 305
VRLRGLPY+ +DI+ F A + + V++ +G R +G+A++Q E A
Sbjct: 465 DCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQG-RPSGDAFIQMTSAERALA 523
Query: 306 ALLK-HREEIGNRYIEIFPSRRNEV-RTHVGSYKGKKIASFPTAK 348
A + H++ + RY+E+ P E+ R +G G+ S P K
Sbjct: 524 AAQRCHKKVMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCK 568
Score = 82.0 bits (201), Expect = 1e-15
Identities = 62/238 (26%), Positives = 101/238 (42%), Gaps = 59/238 (24%)
Query: 242 KSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEE 299
K+ V ++ VVR RGLP+ +++D+ FF GLN+ + ++ +GRR GEA ++F +
Sbjct: 239 KADVVDSETVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRN-GEALIRFVD 297
Query: 300 PEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEE 359
E + AL +H+ +G RYIE++ + E G S A++++ + V
Sbjct: 298 SEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGG------TSLEVARFLSREDQVI-- 349
Query: 360 HEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIIN 419
+ +RGLPF A D++
Sbjct: 350 -------------------------------------------LRLRGLPFSAGPTDVLG 366
Query: 420 FFAPLKPVR-----ITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
F P PV + G+ TG+A F E A AA+ + + + RYIELF
Sbjct: 367 FLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELF 424
Score = 65.9 bits (159), Expect = 8e-11
Identities = 57/204 (27%), Positives = 88/204 (43%), Gaps = 21/204 (10%)
Query: 44 SGRRRLLLLLGAAAAAASQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRA---- 99
+G +L LG T GL P GR P A + A + ALR
Sbjct: 359 AGPTDVLGFLGPECPVTGGTEGLLFVRHPDGR---PTGDAFALFACEELAQAALRRHKGM 415
Query: 100 ------SLLPQSLAAAAAVPTRSYSQESKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIR 153
L + A V R S T L P P + LAP + +R
Sbjct: 416 LGKRYIELFRSTAAEVQQVLNRYASGPLLPTLTAPLLPIP-FPLAPGTGRD------CVR 468
Query: 154 AQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEK- 212
+GLP++ T+ED+L+F + +G+H +LN+ G+ GDA I+M S + A ++
Sbjct: 469 LRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQRC 528
Query: 213 HRMYMGQRYVEVYEINNEDVDALM 236
H+ M +RYVEV + E++ ++
Sbjct: 529 HKKVMKERYVEVVPCSTEEMSRVL 552
Score = 32.7 bits (73), Expect = 0.75
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 25/122 (20%)
Query: 72 PPGRLA--GPPAVATSAAAAA------AASYPALRASLLPQSLAAAAAVPTRSYSQESKT 123
PP +L PP T A AA YP+ ++LLP + AA P Y +
Sbjct: 565 PPCKLPCLSPPTYTTFQATPTLIPTETAALYPS--SALLPAARVPAAPTPVAYYPGPATQ 622
Query: 124 TYLE-----DLPP----------PPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLN 168
YL PP P LA + L+R QG+P++ M+D+L+
Sbjct: 623 LYLNYTAYYPSPPVSPTTVGYLTTPTAALASAPTSVLSQSGALVRMQGVPYTAGMKDLLS 682
Query: 169 FF 170
F
Sbjct: 683 VF 684
>gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a
[Homo sapiens]
Length = 346
Score = 115 bits (289), Expect = 7e-26
Identities = 52/79 (65%), Positives = 64/79 (81%)
Query: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
HFVHMRGLPF+A DI NFF+PL P+R+ ++ + G+ATGEADV F THEDAVAAM KD
Sbjct: 195 HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
Query: 461 RSHVHHRYIELFLNSCPKG 479
++++ HRYIELFLNS P G
Sbjct: 255 KNNMQHRYIELFLNSTPGG 273
Score = 98.6 bits (244), Expect = 1e-20
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQ 305
+DG VRLRGLP+ C++++IV FF GL IV IT MDY+GR TGEA+VQF E+A
Sbjct: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGR-STGEAFVQFASKEIAEN 72
Query: 306 ALLKHREEIGNRYIEIFPSRRNEVR 330
AL KH+E IG+RYIEIF S R+E++
Sbjct: 73 ALGKHKERIGHRYIEIFRSSRSEIK 97
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/81 (29%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
+R +GLP+ C+ E+++ FF I NGI ++ G+ G+A ++ S++ + AL
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
Query: 212 KHRMYMGQRYVEVYEINNEDV 232
KH+ +G RY+E++ + ++
Sbjct: 76 KHKERIGHRYIEIFRSSRSEI 96
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
V +RGLPF + ++I+ FF L+ P IT+ G++TGEA V F + E A A+ K
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 461 RSHVHHRYIELFLNS 475
+ + HRYIE+F +S
Sbjct: 78 KERIGHRYIEIFRSS 92
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
V +RGLP+ E DI +FF+ LN + + + G R TGEA V+F E A A+ K +
Sbjct: 197 VHMRGLPFRATENDIANFFSPLNPIRVHIDIGADG-RATGEADVEFVTHEDAVAAMSKDK 255
Query: 312 EEIGNRYIEIF 322
+ +RYIE+F
Sbjct: 256 NNMQHRYIELF 266
Score = 45.8 bits (107), Expect = 9e-05
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
+ +GLP+ T D+ NFFS IR +H + DG+ G+A +E + +D A+
Sbjct: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
Query: 211 EKHRMYMGQRYVEVY 225
K + M RY+E++
Sbjct: 252 SKDKNNMQHRYIELF 266
>gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b
[Homo sapiens]
Length = 331
Score = 115 bits (289), Expect = 7e-26
Identities = 52/79 (65%), Positives = 64/79 (81%)
Query: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
HFVHMRGLPF+A DI NFF+PL P+R+ ++ + G+ATGEADV F THEDAVAAM KD
Sbjct: 180 HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
Query: 461 RSHVHHRYIELFLNSCPKG 479
++++ HRYIELFLNS P G
Sbjct: 240 KNNMQHRYIELFLNSTPGG 258
Score = 98.6 bits (244), Expect = 1e-20
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQ 305
+DG VRLRGLP+ C++++IV FF GL IV IT MDY+GR TGEA+VQF E+A
Sbjct: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGR-STGEAFVQFASKEIAEN 72
Query: 306 ALLKHREEIGNRYIEIFPSRRNEVR 330
AL KH+E IG+RYIEIF S R+E++
Sbjct: 73 ALGKHKERIGHRYIEIFRSSRSEIK 97
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/81 (29%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
+R +GLP+ C+ E+++ FF I NGI ++ G+ G+A ++ S++ + AL
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
Query: 212 KHRMYMGQRYVEVYEINNEDV 232
KH+ +G RY+E++ + ++
Sbjct: 76 KHKERIGHRYIEIFRSSRSEI 96
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
V +RGLPF + ++I+ FF L+ P IT+ G++TGEA V F + E A A+ K
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 461 RSHVHHRYIELFLNS 475
+ + HRYIE+F +S
Sbjct: 78 KERIGHRYIEIFRSS 92
Score = 45.8 bits (107), Expect = 9e-05
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
+ +GLP+ T D+ NFFS IR +H + DG+ G+A +E + +D A+
Sbjct: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
Query: 211 EKHRMYMGQRYVEVY 225
K + M RY+E++
Sbjct: 237 SKDKNNMQHRYIELF 251
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 95.1 bits (235), Expect = 1e-19
Identities = 102/424 (24%), Positives = 170/424 (40%), Gaps = 102/424 (24%)
Query: 70 PVPPGRLAG-----PPAVATSAAAAAAASYPA-LRASLLPQSLAAAAAV-PTRSYSQESK 122
P+PP ++G PP VA A + P L +L P L V P + SQ S
Sbjct: 237 PLPP--MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSS- 293
Query: 123 TTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGI 182
++ LP P DD++ + G+P+S DV +FF R+ + +
Sbjct: 294 ---VKPLPINP-------------DDLY-VSVHGMPFSAMENDVRDFFHGLRV----DAV 332
Query: 183 HFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVK 242
H L + G+ G+ L++ S QD +AL+++RM M QRYVEV A + K
Sbjct: 333 HLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFK 392
Query: 243 S------------------------------SPVVNDGVVRLRGLPYSCNEKDIVDFFAG 272
SP V L+GLP+ K ++DFF
Sbjct: 393 QNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKK 452
Query: 273 LNIVDITFVMDYRGRRK-TGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRT 331
L+IV+ + + Y K TGE +V+F AL +H++ +GNR+I++ P + +
Sbjct: 453 LDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLE 512
Query: 332 HVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEA 391
+ + K++ +F Y ++ E +VN
Sbjct: 513 KIDMIR-KRLQNF---SYDQREMILNPEGDVN---------------------------- 540
Query: 392 ADFGTTSSLHFVHMRGLPFQANAQDIINFF--APLKPVRITMEYSSSGKATGEADVHFET 449
S+ H+ +PF D++ F P+ + + ++G+ G+A V F+
Sbjct: 541 ------SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKN 594
Query: 450 HEDA 453
+DA
Sbjct: 595 EDDA 598
Score = 82.8 bits (203), Expect = 6e-16
Identities = 66/234 (28%), Positives = 108/234 (46%), Gaps = 28/234 (11%)
Query: 241 VKSSPVVNDGV-VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEE 299
VK P+ D + V + G+P+S E D+ DFF GL + + + D+ GR G V+F
Sbjct: 294 VKPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNN-GNGLVKFLS 352
Query: 300 PEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEE 359
P+ +AL ++R + RY+E+ P+ + G K+ P+ + T P
Sbjct: 353 PQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMG-PSGQ--THP------ 403
Query: 360 HEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIIN 419
P K K + P A F V+++GLPF+A + +I+
Sbjct: 404 --------PPQTLPRSKSPSGQKRSRSRSPHEAGF-------CVYLKGLPFEAENKHVID 448
Query: 420 FFAPLKPVR--ITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIEL 471
FF L V I + Y +GKATGE V F D AA+ + + ++ +R+I++
Sbjct: 449 FFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
Score = 73.2 bits (178), Expect = 5e-13
Identities = 49/186 (26%), Positives = 92/186 (49%), Gaps = 21/186 (11%)
Query: 150 FLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
F + +GLP+ + V++FF I E+ I+ +GK G+ +E +E D + A
Sbjct: 430 FCVYLKGLPFEAENKHVIDFFKKLDIV--EDSIYIAYGPNGKATGEGFVEFRNEADYKAA 487
Query: 210 LEKHRMYMGQRYVEVYEINN----EDVDALMKSLQ----------VKSSPVVNDGVV--R 253
L +H+ YMG R+++V+ I E +D + K LQ + VN V
Sbjct: 488 LCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCAH 547
Query: 254 LRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
+ +P+S + D++ F G+ + + + ++D G + G+A VQF+ + A ++ HR
Sbjct: 548 ITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNG-QGLGQALVQFKNEDDARKSERLHR 606
Query: 312 EEIGNR 317
+++ R
Sbjct: 607 KKLNGR 612
Score = 48.5 bits (114), Expect = 1e-05
Identities = 25/82 (30%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 157 LPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMY 216
+P+S T DVL F + EN +H L++ +G+ G AL++ ++E D +K+ HR
Sbjct: 551 IPFSITKMDVLQFLEGIPV--DENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKK 608
Query: 217 MGQRYVEVYEINNEDVDALMKS 238
+ R V+ + ED+ + K+
Sbjct: 609 LNGREAFVHVVTLEDMREIEKN 630
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAM--L 458
+ ++ +PF + +I++FF + P + ++Y+ G TGEA V FE+ ++A AA+ L
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
Query: 459 KDRSHVHHRYIELFL 473
DR + R ++L L
Sbjct: 918 NDRP-IGSRKVKLVL 931
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGR-RKTGEAYVQFEEPEMANQALLK 309
V++++ +P++ + +I+DFF G ++ + + Y + TGEA V FE + A A++
Sbjct: 857 VIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVID 916
Query: 310 HREE-IGNRYIEI 321
+ IG+R +++
Sbjct: 917 LNDRPIGSRKVKL 929
Score = 33.9 bits (76), Expect = 0.34
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 7/85 (8%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQALL 308
V+RL+GLP DI FF+GL I D + V + GEA++ F E A ++
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV-----GGELGEAFIVFATDEDARLGMM 58
Query: 309 KHREEIGNRYIEIFPSRRNEVRTHV 333
+ I + + S + E++ +
Sbjct: 59 RTGGTIKGSKVTLLLSSKTEMQNMI 83
Score = 32.0 bits (71), Expect = 1.3
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK----PVRITMEYSSSGKATGEADVHFETHEDAVAAML 458
+ ++GLP A DI +FF+ L V I G GEA + F T EDA M+
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV------GGELGEAFIVFATDEDARLGMM 58
Query: 459 KDRSHVHHRYIELFLNS 475
+ + + L L+S
Sbjct: 59 RTGGTIKGSKVTLLLSS 75
Score = 30.8 bits (68), Expect = 2.8
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQ 207
+IR QGLP D+ +FFS I +G G+H + G G+A I +++D +
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDAR 54
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 95.1 bits (235), Expect = 1e-19
Identities = 102/424 (24%), Positives = 170/424 (40%), Gaps = 102/424 (24%)
Query: 70 PVPPGRLAG-----PPAVATSAAAAAAASYPA-LRASLLPQSLAAAAAV-PTRSYSQESK 122
P+PP ++G PP VA A + P L +L P L V P + SQ S
Sbjct: 237 PLPP--MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSS- 293
Query: 123 TTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGI 182
++ LP P DD++ + G+P+S DV +FF R+ + +
Sbjct: 294 ---VKPLPINP-------------DDLY-VSVHGMPFSAMENDVRDFFHGLRV----DAV 332
Query: 183 HFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVK 242
H L + G+ G+ L++ S QD +AL+++RM M QRYVEV A + K
Sbjct: 333 HLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFK 392
Query: 243 S------------------------------SPVVNDGVVRLRGLPYSCNEKDIVDFFAG 272
SP V L+GLP+ K ++DFF
Sbjct: 393 QNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKK 452
Query: 273 LNIVDITFVMDYRGRRK-TGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRT 331
L+IV+ + + Y K TGE +V+F AL +H++ +GNR+I++ P + +
Sbjct: 453 LDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLE 512
Query: 332 HVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEA 391
+ + K++ +F Y ++ E +VN
Sbjct: 513 KIDMIR-KRLQNF---SYDQREMILNPEGDVN---------------------------- 540
Query: 392 ADFGTTSSLHFVHMRGLPFQANAQDIINFF--APLKPVRITMEYSSSGKATGEADVHFET 449
S+ H+ +PF D++ F P+ + + ++G+ G+A V F+
Sbjct: 541 ------SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKN 594
Query: 450 HEDA 453
+DA
Sbjct: 595 EDDA 598
Score = 82.8 bits (203), Expect = 6e-16
Identities = 66/234 (28%), Positives = 108/234 (46%), Gaps = 28/234 (11%)
Query: 241 VKSSPVVNDGV-VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEE 299
VK P+ D + V + G+P+S E D+ DFF GL + + + D+ GR G V+F
Sbjct: 294 VKPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNN-GNGLVKFLS 352
Query: 300 PEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEE 359
P+ +AL ++R + RY+E+ P+ + G K+ P+ + T P
Sbjct: 353 PQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMG-PSGQ--THP------ 403
Query: 360 HEVNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIIN 419
P K K + P A F V+++GLPF+A + +I+
Sbjct: 404 --------PPQTLPRSKSPSGQKRSRSRSPHEAGF-------CVYLKGLPFEAENKHVID 448
Query: 420 FFAPLKPVR--ITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIEL 471
FF L V I + Y +GKATGE V F D AA+ + + ++ +R+I++
Sbjct: 449 FFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
Score = 73.2 bits (178), Expect = 5e-13
Identities = 49/186 (26%), Positives = 92/186 (49%), Gaps = 21/186 (11%)
Query: 150 FLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 209
F + +GLP+ + V++FF I E+ I+ +GK G+ +E +E D + A
Sbjct: 430 FCVYLKGLPFEAENKHVIDFFKKLDIV--EDSIYIAYGPNGKATGEGFVEFRNEADYKAA 487
Query: 210 LEKHRMYMGQRYVEVYEINN----EDVDALMKSLQ----------VKSSPVVNDGVV--R 253
L +H+ YMG R+++V+ I E +D + K LQ + VN V
Sbjct: 488 LCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCAH 547
Query: 254 LRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
+ +P+S + D++ F G+ + + + ++D G + G+A VQF+ + A ++ HR
Sbjct: 548 ITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNG-QGLGQALVQFKNEDDARKSERLHR 606
Query: 312 EEIGNR 317
+++ R
Sbjct: 607 KKLNGR 612
Score = 48.5 bits (114), Expect = 1e-05
Identities = 25/82 (30%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 157 LPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMY 216
+P+S T DVL F + EN +H L++ +G+ G AL++ ++E D +K+ HR
Sbjct: 551 IPFSITKMDVLQFLEGIPV--DENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKK 608
Query: 217 MGQRYVEVYEINNEDVDALMKS 238
+ R V+ + ED+ + K+
Sbjct: 609 LNGREAFVHVVTLEDMREIEKN 630
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAM--L 458
+ ++ +PF + +I++FF + P + ++Y+ G TGEA V FE+ ++A AA+ L
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
Query: 459 KDRSHVHHRYIELFL 473
DR + R ++L L
Sbjct: 918 NDRP-IGSRKVKLVL 931
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGR-RKTGEAYVQFEEPEMANQALLK 309
V++++ +P++ + +I+DFF G ++ + + Y + TGEA V FE + A A++
Sbjct: 857 VIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVID 916
Query: 310 HREE-IGNRYIEI 321
+ IG+R +++
Sbjct: 917 LNDRPIGSRKVKL 929
Score = 33.9 bits (76), Expect = 0.34
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 7/85 (8%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQALL 308
V+RL+GLP DI FF+GL I D + V + GEA++ F E A ++
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV-----GGELGEAFIVFATDEDARLGMM 58
Query: 309 KHREEIGNRYIEIFPSRRNEVRTHV 333
+ I + + S + E++ +
Sbjct: 59 RTGGTIKGSKVTLLLSSKTEMQNMI 83
Score = 32.0 bits (71), Expect = 1.3
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK----PVRITMEYSSSGKATGEADVHFETHEDAVAAML 458
+ ++GLP A DI +FF+ L V I G GEA + F T EDA M+
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV------GGELGEAFIVFATDEDARLGMM 58
Query: 459 KDRSHVHHRYIELFLNS 475
+ + + L L+S
Sbjct: 59 RTGGTIKGSKVTLLLSS 75
Score = 30.8 bits (68), Expect = 2.8
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQ 207
+IR QGLP D+ +FFS I +G G+H + G G+A I +++D +
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDAR 54
>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
Length = 1001
Score = 88.6 bits (218), Expect = 1e-17
Identities = 80/337 (23%), Positives = 135/337 (40%), Gaps = 74/337 (21%)
Query: 155 QGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHR 214
+GLP+ +DV FFS + +G+ FL + DG+ GDA+++ S D L+ HR
Sbjct: 160 RGLPYLVNEDDVRVFFSGLCV----DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHR 215
Query: 215 MYMGQRYVEVYEINNE-----------DVDALMKSLQVKSSPVVNDG------------- 250
+MG R++EV + + + + D L +S + +ND
Sbjct: 216 SFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRR 275
Query: 251 ---------VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPE 301
V L+ L S +E+D+ +FF G ++ D Y+ +T A+V F+ +
Sbjct: 276 TRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLK 335
Query: 302 MANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHE 361
N AL H+ + R + I P R ++ + Y+ K+ S
Sbjct: 336 DYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSL----------------- 378
Query: 362 VNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
E + P V +K + G + +++R PF ++ FF
Sbjct: 379 ---------------ERDRPGHVSQKYSQE---GNSGQKLCIYIRNFPFDVTKVEVQKFF 420
Query: 422 AP--LKPVRITMEYSSSGKATGEADVHFETHEDAVAA 456
A L I + Y G GEA V F++ E A+ A
Sbjct: 421 ADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA 457
Score = 62.4 bits (150), Expect = 9e-10
Identities = 80/381 (20%), Positives = 145/381 (38%), Gaps = 89/381 (23%)
Query: 151 LIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
+IR GLP+ D+ +FF+ I +G G+H + G G+A I +++D ++A+
Sbjct: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
Query: 211 EKHRMYMGQRYVEVY-----------EINNED-------------VDALMKSLQVKSSPV 246
+ ++ VE++ E+ D VD+L ++
Sbjct: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
Query: 247 VNDGV----------------------------------VRLRGLPYSCNEKDIVDFFAG 272
N G + LRGLPY NE D+ FF+G
Sbjct: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
Query: 273 LNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTH 332
L + + F+ + G R G+A V+F A+ L HR +G+R+IE+ +
Sbjct: 178 LCVDGVIFLKHHDG-RNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ-WIE 235
Query: 333 VGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEAA 392
G K+ ++ + P + + H F + P+ + P
Sbjct: 236 FGGNAVKEGDVLRRSEEHSPPRGINDRH-----------FRKRSHSKSPRRTRSRSPLG- 283
Query: 393 DFGTTSSLHFVHMRGLPFQANAQDIINFF--APLKPVRITMEYSSSGKATGEADVHFETH 450
+VH++ L + +D+ NFF L +I Y + T A V F+T
Sbjct: 284 --------FYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTL 334
Query: 451 EDAVAAMLKDRSHVHHRYIEL 471
+D A+ ++ + +R + +
Sbjct: 335 KDYNTALSLHKTVLQYRPVHI 355
Score = 53.1 bits (126), Expect = 5e-07
Identities = 58/241 (24%), Positives = 96/241 (39%), Gaps = 31/241 (12%)
Query: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKH 310
V+RL GLP+ DI FF GL I D V G + GEA++ F E A +A+ +
Sbjct: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPD-GGVHIIGG--EIGEAFIIFATDEDARRAISRS 60
Query: 311 REEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMT 370
I + +E+F S + E++ + + ++ + + +
Sbjct: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSL------------SN 108
Query: 371 AFESEKEIELPKEVPEKLPEAADFGTTSSLH----------------FVHMRGLPFQANA 414
ES KE + + A F T + H ++ +RGLP+ N
Sbjct: 109 FIESVKEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNE 168
Query: 415 QDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLN 474
D+ FF+ L + G+ G+A V F + DA + RS + R+IE+
Sbjct: 169 DDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQG 228
Query: 475 S 475
S
Sbjct: 229 S 229
Score = 40.0 bits (92), Expect = 0.005
Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 4/63 (6%)
Query: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAM--L 458
+ + LPF+AN +I++FF + P ++++Y+ G TGEA V + +A+AA+ L
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
Query: 459 KDR 461
DR
Sbjct: 987 NDR 989
Score = 32.7 bits (73), Expect = 0.75
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
I + P+ T +V FF+D + E+ I+ L + G G+AL++ +SE+ KA
Sbjct: 402 IYIRNFPFDVTKVEVQKFFADFLL--AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAER 459
Query: 212 KHR 214
+R
Sbjct: 460 LNR 462
Score = 30.8 bits (68), Expect = 2.8
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGR-RKTGEAYV 295
+++ LP+ N +I+DFF G I+ + + Y + TGEA V
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIV 971
>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/233 (23%), Positives = 105/233 (45%), Gaps = 24/233 (10%)
Query: 130 PPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRD 189
PP E ++E ++ +G P++ T ++V+ F + + I + N
Sbjct: 274 PPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAH 329
Query: 190 GKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKS------ 243
G + G ++ +E++V++AL+ +R YMG RY+EV+ N KS
Sbjct: 330 GNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRIL 389
Query: 244 ------SPVVNDGVVRLRGLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQ 296
+ G + +R LPY+ E+D+ F+ + ++ + +D ++ G A++
Sbjct: 390 GENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFIT 449
Query: 297 FEEPEMANQALLKHREEI-GNRYIEIFPS----RRNEVRTHVG--SYKGKKIA 342
F PE A +A + ++ R + + PS +E + +G SYK KK A
Sbjct: 450 FMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEA 502
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/92 (32%), Positives = 49/92 (53%)
Query: 381 PKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKAT 440
P E + + A+ ++ H V +RG PF ++++ F APLKPV I + ++ G T
Sbjct: 274 PPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKT 333
Query: 441 GEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
G V F E+ A+ +R ++ RYIE+F
Sbjct: 334 GYIFVDFSNEEEVKQALKCNREYMGGRYIEVF 365
Score = 35.0 bits (79), Expect = 0.15
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 15/95 (15%)
Query: 382 KEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDI---INFFAPLKPVRITMEYSSSGK 438
K+VP K TTS + +R +PFQA++++I + F LK VR+ + + +G
Sbjct: 823 KQVPRKQ-------TTSK---ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGT 872
Query: 439 ATGEADVHFETHEDAVAAM--LKDRSHVHHRYIEL 471
G V F T +DA A L +H++ R + L
Sbjct: 873 HRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/233 (23%), Positives = 105/233 (45%), Gaps = 24/233 (10%)
Query: 130 PPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRD 189
PP E ++E ++ +G P++ T ++V+ F + + I + N
Sbjct: 274 PPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAH 329
Query: 190 GKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKS------ 243
G + G ++ +E++V++AL+ +R YMG RY+EV+ N KS
Sbjct: 330 GNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRIL 389
Query: 244 ------SPVVNDGVVRLRGLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQ 296
+ G + +R LPY+ E+D+ F+ + ++ + +D ++ G A++
Sbjct: 390 GENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFIT 449
Query: 297 FEEPEMANQALLKHREEI-GNRYIEIFPS----RRNEVRTHVG--SYKGKKIA 342
F PE A +A + ++ R + + PS +E + +G SYK KK A
Sbjct: 450 FMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEA 502
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/92 (32%), Positives = 49/92 (53%)
Query: 381 PKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKAT 440
P E + + A+ ++ H V +RG PF ++++ F APLKPV I + ++ G T
Sbjct: 274 PPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKT 333
Query: 441 GEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
G V F E+ A+ +R ++ RYIE+F
Sbjct: 334 GYIFVDFSNEEEVKQALKCNREYMGGRYIEVF 365
Score = 35.0 bits (79), Expect = 0.15
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 15/95 (15%)
Query: 382 KEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDI---INFFAPLKPVRITMEYSSSGK 438
K+VP K TTS + +R +PFQA++++I + F LK VR+ + + +G
Sbjct: 823 KQVPRKQ-------TTSK---ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGT 872
Query: 439 ATGEADVHFETHEDAVAAM--LKDRSHVHHRYIEL 471
G V F T +DA A L +H++ R + L
Sbjct: 873 HRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
>gi|226497574 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/233 (23%), Positives = 105/233 (45%), Gaps = 24/233 (10%)
Query: 130 PPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRD 189
PP E ++E ++ +G P++ T ++V+ F + + I + N
Sbjct: 274 PPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAH 329
Query: 190 GKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKS------ 243
G + G ++ +E++V++AL+ +R YMG RY+EV+ N KS
Sbjct: 330 GNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRIL 389
Query: 244 ------SPVVNDGVVRLRGLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQ 296
+ G + +R LPY+ E+D+ F+ + ++ + +D ++ G A++
Sbjct: 390 GENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFIT 449
Query: 297 FEEPEMANQALLKHREEI-GNRYIEIFPS----RRNEVRTHVG--SYKGKKIA 342
F PE A +A + ++ R + + PS +E + +G SYK KK A
Sbjct: 450 FMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEA 502
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/92 (32%), Positives = 49/92 (53%)
Query: 381 PKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKAT 440
P E + + A+ ++ H V +RG PF ++++ F APLKPV I + ++ G T
Sbjct: 274 PPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKT 333
Query: 441 GEADVHFETHEDAVAAMLKDRSHVHHRYIELF 472
G V F E+ A+ +R ++ RYIE+F
Sbjct: 334 GYIFVDFSNEEEVKQALKCNREYMGGRYIEVF 365
Score = 35.0 bits (79), Expect = 0.15
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 15/95 (15%)
Query: 382 KEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDI---INFFAPLKPVRITMEYSSSGK 438
K+VP K TTS + +R +PFQA++++I + F LK VR+ + + +G
Sbjct: 823 KQVPRKQ-------TTSK---ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGT 872
Query: 439 ATGEADVHFETHEDAVAAM--LKDRSHVHHRYIEL 471
G V F T +DA A L +H++ R + L
Sbjct: 873 HRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 50.4 bits (119), Expect = 3e-06
Identities = 64/275 (23%), Positives = 106/275 (38%), Gaps = 56/275 (20%)
Query: 54 GAAAAAASQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVP 113
GAAAAA + G G G AT AAAAA S A+
Sbjct: 10 GAAAAATAAVGG------SAGEQEGAMVAATQGAAAAAGSGAGTGGG--------TASGG 55
Query: 114 TRSYSQESKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFS-- 171
T S ES+ ++ SK EE+ +F+ GL W T +D+ ++FS
Sbjct: 56 TEGGSAESEGAKID-----------ASKNEEDEGKMFI---GGLSWDTTKKDLKDYFSKF 101
Query: 172 ----DCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEI 227
DC ++ L G+ RG + + + V K +++ + +++
Sbjct: 102 GEVVDCTLK--------LDPITGRSRGFGFVLFKESESVDKVMDQ----------KEHKL 143
Query: 228 NNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVD-ITFVMDYRG 286
N + +D PV + + GL E+ I ++F G V+ I MD +
Sbjct: 144 NGKVIDPKRAKAMKTKEPVKK---IFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKT 200
Query: 287 RRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEI 321
++ G ++ F+E E + + K +G EI
Sbjct: 201 NKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEI 235
Score = 37.0 bits (84), Expect = 0.040
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQFEEPEMANQA 306
++G + + GL + +KD+ D+F+ +VD T +D R G +V F+E E ++
Sbjct: 76 DEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKV 135
Query: 307 LLKHREEIGNRYIEIFPSRRNEVRT 331
+ + ++ + I+ P R ++T
Sbjct: 136 MDQKEHKLNGKVID--PKRAKAMKT 158
>gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d
[Homo sapiens]
Length = 287
Score = 50.4 bits (119), Expect = 3e-06
Identities = 64/275 (23%), Positives = 106/275 (38%), Gaps = 56/275 (20%)
Query: 54 GAAAAAASQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVP 113
GAAAAA + G G G AT AAAAA S A+
Sbjct: 10 GAAAAATAAVGG------SAGEQEGAMVAATQGAAAAAGSGAGTGGG--------TASGG 55
Query: 114 TRSYSQESKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFS-- 171
T S ES+ ++ SK EE+ +F+ GL W T +D+ ++FS
Sbjct: 56 TEGGSAESEGAKID-----------ASKNEEDEGKMFI---GGLSWDTTKKDLKDYFSKF 101
Query: 172 ----DCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEI 227
DC ++ L G+ RG + + + V K +++ + +++
Sbjct: 102 GEVVDCTLK--------LDPITGRSRGFGFVLFKESESVDKVMDQ----------KEHKL 143
Query: 228 NNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVD-ITFVMDYRG 286
N + +D PV + + GL E+ I ++F G V+ I MD +
Sbjct: 144 NGKVIDPKRAKAMKTKEPVKK---IFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKT 200
Query: 287 RRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEI 321
++ G ++ F+E E + + K +G EI
Sbjct: 201 NKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEI 235
Score = 37.0 bits (84), Expect = 0.040
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
Query: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQFEEPEMANQA 306
++G + + GL + +KD+ D+F+ +VD T +D R G +V F+E E ++
Sbjct: 76 DEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKV 135
Query: 307 LLKHREEIGNRYIEIFPSRRNEVRT 331
+ + ++ + I+ P R ++T
Sbjct: 136 MDQKEHKLNGKVID--PKRAKAMKT 158
>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
[Homo sapiens]
Length = 355
Score = 48.5 bits (114), Expect = 1e-05
Identities = 63/277 (22%), Positives = 104/277 (37%), Gaps = 41/277 (14%)
Query: 54 GAAAAAASQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVP 113
GAAAAA + G G G AT AAAAA S +A
Sbjct: 10 GAAAAATAAVGG------SAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAES 63
Query: 114 TRSYSQESKTTYLE--DLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFS 171
+ SK E P E A ++ EE + + GL W T +D+ ++FS
Sbjct: 64 EGAKIDASKNEEDEGHSNSSPRHSEAATAQREE-----WKMFIGGLSWDTTKKDLKDYFS 118
Query: 172 ------DCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVY 225
DC ++ L G+ RG + + + V K +++ + +
Sbjct: 119 KFGEVVDCTLK--------LDPITGRSRGFGFVLFKESESVDKVMDQ----------KEH 160
Query: 226 EINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVD-ITFVMDY 284
++N + +D PV + + GL E+ I ++F G V+ I MD
Sbjct: 161 KLNGKVIDPKRAKAMKTKEPVKK---IFVGGLSPDTPEEKIREYFGGFGEVESIELPMDN 217
Query: 285 RGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEI 321
+ ++ G ++ F+E E + + K +G EI
Sbjct: 218 KTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEI 254
Score = 35.0 bits (79), Expect = 0.15
Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 256 GLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEI 314
GL + +KD+ D+F+ +VD T +D R G +V F+E E ++ + + ++
Sbjct: 103 GLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKL 162
Query: 315 GNRYIEIFPSRRNEVRT 331
+ I+ P R ++T
Sbjct: 163 NGKVID--PKRAKAMKT 177
>gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c
[Homo sapiens]
Length = 306
Score = 48.5 bits (114), Expect = 1e-05
Identities = 63/277 (22%), Positives = 104/277 (37%), Gaps = 41/277 (14%)
Query: 54 GAAAAAASQTRGLQTGPVPPGRLAGPPAVATSAAAAAAASYPALRASLLPQSLAAAAAVP 113
GAAAAA + G G G AT AAAAA S +A
Sbjct: 10 GAAAAATAAVGG------SAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAES 63
Query: 114 TRSYSQESKTTYLE--DLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFS 171
+ SK E P E A ++ EE + + GL W T +D+ ++FS
Sbjct: 64 EGAKIDASKNEEDEGHSNSSPRHSEAATAQREE-----WKMFIGGLSWDTTKKDLKDYFS 118
Query: 172 ------DCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVY 225
DC ++ L G+ RG + + + V K +++ + +
Sbjct: 119 KFGEVVDCTLK--------LDPITGRSRGFGFVLFKESESVDKVMDQ----------KEH 160
Query: 226 EINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFAGLNIVD-ITFVMDY 284
++N + +D PV + + GL E+ I ++F G V+ I MD
Sbjct: 161 KLNGKVIDPKRAKAMKTKEPVKK---IFVGGLSPDTPEEKIREYFGGFGEVESIELPMDN 217
Query: 285 RGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEI 321
+ ++ G ++ F+E E + + K +G EI
Sbjct: 218 KTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEI 254
Score = 35.0 bits (79), Expect = 0.15
Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 256 GLPYSCNEKDIVDFFAGLN-IVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEI 314
GL + +KD+ D+F+ +VD T +D R G +V F+E E ++ + + ++
Sbjct: 103 GLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKL 162
Query: 315 GNRYIEIFPSRRNEVRT 331
+ I+ P R ++T
Sbjct: 163 NGKVID--PKRAKAMKT 177
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 133 PEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFSDCRI-----RNGENGIHFLLN 187
P+ +L P +E D I QGL S T++D+ +FF C + R G+ IH L+
Sbjct: 288 PDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLD 347
Query: 188 RD-GKRRGDALIEMESEQDVQKALE 211
++ GK +GDA + E + A+E
Sbjct: 348 KETGKPKGDATVSYEDPPTAKAAVE 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,396,423
Number of Sequences: 37866
Number of extensions: 950304
Number of successful extensions: 6992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 5819
Number of HSP's gapped (non-prelim): 880
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.