Guide to the Human Genome
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Search of human proteins with 148839294

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148839294 Ca2+-dependent activator protein for secretion 2
isoform a [Homo sapiens]
         (1296 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148839294 Ca2+-dependent activator protein for secretion 2 is...  2586   0.0  
gi|148839284 Ca2+-dependent activator protein for secretion 2 is...  2453   0.0  
gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo s...  2033   0.0  
gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo s...  1963   0.0  
gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo s...  1934   0.0  
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]                    55   6e-07
gi|122937247 unc-13 homolog A [Homo sapiens]                           52   5e-06
gi|122937514 unc-13 homolog C [Homo sapiens]                           48   7e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    44   0.001
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    40   0.019
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    40   0.019
gi|50083279 centrosome protein 4 [Homo sapiens]                        39   0.042
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    38   0.055
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]    38   0.055
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    37   0.094
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    37   0.16 
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    37   0.16 
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    36   0.27 
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma...    36   0.27 
gi|4758968 cytohesin 3 [Homo sapiens]                                  36   0.27 
gi|71061468 centromere protein E [Homo sapiens]                        35   0.36 
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    35   0.36 
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            35   0.47 
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            35   0.47 
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            35   0.47 
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       35   0.47 
gi|5174457 kinetochore associated 2 [Homo sapiens]                     35   0.61 
gi|33946313 ninein isoform 4 [Homo sapiens]                            35   0.61 
gi|33946321 ninein isoform 5 [Homo sapiens]                            35   0.61 
gi|148536871 ninein isoform 1 [Homo sapiens]                           35   0.61 

>gi|148839294 Ca2+-dependent activator protein for secretion 2 isoform
            a [Homo sapiens]
          Length = 1296

 Score = 2586 bits (6704), Expect = 0.0
 Identities = 1296/1296 (100%), Positives = 1296/1296 (100%)

Query: 1    MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60
            MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS
Sbjct: 1    MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60

Query: 61   PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120
            PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ
Sbjct: 61   PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120

Query: 121  LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180
            LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN
Sbjct: 121  LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180

Query: 181  IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240
            IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY
Sbjct: 181  IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240

Query: 241  EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300
            EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD
Sbjct: 241  EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300

Query: 301  MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
            MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD
Sbjct: 301  MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360

Query: 361  VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
            VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP
Sbjct: 361  VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420

Query: 421  RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480
            RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV
Sbjct: 421  RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480

Query: 481  RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540
            RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG
Sbjct: 481  RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540

Query: 541  YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600
            YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ
Sbjct: 541  YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600

Query: 601  TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660
            TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN
Sbjct: 601  TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660

Query: 661  DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720
            DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF
Sbjct: 661  DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720

Query: 721  CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780
            CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS
Sbjct: 721  CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780

Query: 781  LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840
            LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI
Sbjct: 781  LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840

Query: 841  LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900
            LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD
Sbjct: 841  LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900

Query: 901  SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960
            SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ
Sbjct: 901  SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960

Query: 961  PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020
            PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ
Sbjct: 961  PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020

Query: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080
            MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC
Sbjct: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080

Query: 1081 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK 1140
            TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK
Sbjct: 1081 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK 1140

Query: 1141 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE 1200
            LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE
Sbjct: 1141 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE 1200

Query: 1201 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY 1260
            KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY
Sbjct: 1201 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY 1260

Query: 1261 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296
            DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG
Sbjct: 1261 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296


>gi|148839284 Ca2+-dependent activator protein for secretion 2 isoform
            b [Homo sapiens]
          Length = 1255

 Score = 2453 bits (6358), Expect = 0.0
 Identities = 1248/1301 (95%), Positives = 1248/1301 (95%), Gaps = 51/1301 (3%)

Query: 1    MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60
            MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS
Sbjct: 1    MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60

Query: 61   PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120
            PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ
Sbjct: 61   PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120

Query: 121  LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180
            LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN
Sbjct: 121  LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180

Query: 181  IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240
            IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY
Sbjct: 181  IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240

Query: 241  EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300
            EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD
Sbjct: 241  EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300

Query: 301  MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
            MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD
Sbjct: 301  MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360

Query: 361  VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
            VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP
Sbjct: 361  VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420

Query: 421  RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480
            RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV
Sbjct: 421  RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480

Query: 481  RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540
            RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG
Sbjct: 481  RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540

Query: 541  YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600
            YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ
Sbjct: 541  YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600

Query: 601  TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660
            TQKLNPKGGTLHADAQL    ADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN
Sbjct: 601  TQKLNPKGGTLHADAQLY---ADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 657

Query: 661  DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720
            DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF
Sbjct: 658  DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 717

Query: 721  CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780
            CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS
Sbjct: 718  CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 777

Query: 781  LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840
            LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI
Sbjct: 778  LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 837

Query: 841  LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900
            LHLAELCIEVLQQNEEHHA   EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD
Sbjct: 838  LHLAELCIEVLQQNEEHHA---EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 894

Query: 901  SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960
            SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ
Sbjct: 895  SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 954

Query: 961  PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020
            PV                                         NGSATSEDLFWKLDALQ
Sbjct: 955  PV----------------------------------------NNGSATSEDLFWKLDALQ 974

Query: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080
            MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC
Sbjct: 975  MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1034

Query: 1081 TMFNVLVDAKKQSTKLCALDGGQE-----QQYHSKIDDLIDNSVKEIISLLVSKFVSVLE 1135
            TMFNVLVDAKKQSTKLCALDGGQE     QQYHSKIDDLIDNSVKEIISLLVSKFVSVLE
Sbjct: 1035 TMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLE 1094

Query: 1136 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE 1195
            GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE
Sbjct: 1095 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE 1154

Query: 1196 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL 1255
            EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL
Sbjct: 1155 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL 1214

Query: 1256 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296
            NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG
Sbjct: 1215 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1255


>gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo
            sapiens]
          Length = 1353

 Score = 2033 bits (5268), Expect = 0.0
 Identities = 1022/1351 (75%), Positives = 1158/1351 (85%), Gaps = 57/1351 (4%)

Query: 1    MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51
            MLDPSSSEEESDE +EEES ++VL +A S  R  P+ T EG   + G  GGG        
Sbjct: 1    MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60

Query: 52   ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86
                                    G  R  SPSPSV+SE  ++E +R   +E+ER+ RLQ
Sbjct: 61   AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120

Query: 87   LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146
            LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV
Sbjct: 121  LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180

Query: 147  RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206
            +SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK
Sbjct: 181  QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240

Query: 207  YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266
            +DAIYRGEED  KQ  RM  SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN 
Sbjct: 241  FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300

Query: 267  DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326
            DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS
Sbjct: 301  DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360

Query: 327  KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386
            KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV
Sbjct: 361  KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419

Query: 387  YCTMEVEG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445
            YCTMEVEG EKLQTDQAEAS+P WGTQGDF+TTH  P VKVKLFTESTGVLALEDKELGR
Sbjct: 420  YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479

Query: 446  VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505
            VIL+PT NS K +E H+M V KN  D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW
Sbjct: 480  VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539

Query: 506  KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565
            KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG  FFNAVKEG
Sbjct: 540  KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599

Query: 566  DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADAQLSGKDADR 624
            DTVIFASDDEQDRILWVQAMYRATGQS+KPVP  Q QKLN KGG +   DA +S   ADR
Sbjct: 600  DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659

Query: 625  FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 684
             QKHGMDEFIS+NPC  DHA LF ++QR TLDHRLNDSYSCLGWFSPGQVFVLDEYCAR 
Sbjct: 660  AQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARN 719

Query: 685  GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 744
            GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF
Sbjct: 720  GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 779

Query: 745  EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 804
            EEIKERL  LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R
Sbjct: 780  EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 839

Query: 805  KCLEKAALINYTRLTEYAKIEETMNQA-------SPARKLEEILHLAELCIEVLQQNEEH 857
            KCLE+AAL+NY+RL+EYAKIEE    A       +PA+KLE+ + LAEL IEVLQQNEEH
Sbjct: 840  KCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEH 899

Query: 858  HAEGR----EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLR 913
            HAE      EAFAWW DL+ EHAE F +LF VDMD ALE QP D+WDSFPLFQLLN+FLR
Sbjct: 900  HAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLR 959

Query: 914  NDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVA 973
             D  LCNGKFHKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PVK++ ++LPNV 
Sbjct: 960  TDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVN 1019

Query: 974  LP-----KVPSLPLNLP----QIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVF 1024
            LP     KVP+LP+N+P    Q+P  S  SWM ++Y++ NGS TSEDLFWKLDALQ F+ 
Sbjct: 1020 LPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIR 1079

Query: 1025 DLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFN 1084
            DLHWPE+EF  HLEQRLKLMASDM+E+CVKRTR AFE+KLQK S++TD R+P S+CTMFN
Sbjct: 1080 DLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFN 1139

Query: 1085 VLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRY 1144
            V+VDAK QSTKLC+++ GQE QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+KLSRY
Sbjct: 1140 VMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRY 1199

Query: 1145 DEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFD 1204
            DEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE+LFD
Sbjct: 1200 DEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFD 1259

Query: 1205 QWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVH 1264
            QWY+SSM VIC WLTDR+DLQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY+T+ 
Sbjct: 1260 QWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIR 1319

Query: 1265 RRLTVEEATASVSEGGGLQGITMKDSDEEEE 1295
             RLTVEEATASVSEGGGLQGI+MKDSDEE+E
Sbjct: 1320 NRLTVEEATASVSEGGGLQGISMKDSDEEDE 1350


>gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo
            sapiens]
          Length = 1314

 Score = 1963 bits (5086), Expect = 0.0
 Identities = 998/1355 (73%), Positives = 1123/1355 (82%), Gaps = 104/1355 (7%)

Query: 1    MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51
            MLDPSSSEEESDE +EEES ++VL +A S  R  P+ T EG   + G  GGG        
Sbjct: 1    MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60

Query: 52   ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86
                                    G  R  SPSPSV+SE  ++E +R   +E+ER+ RLQ
Sbjct: 61   AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120

Query: 87   LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146
            LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV
Sbjct: 121  LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180

Query: 147  RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206
            +SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK
Sbjct: 181  QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240

Query: 207  YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266
            +DAIYRGEED  KQ  RM  SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN 
Sbjct: 241  FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300

Query: 267  DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326
            DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS
Sbjct: 301  DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360

Query: 327  KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386
            KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV
Sbjct: 361  KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419

Query: 387  YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445
            YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH  P VKVKLFTESTGVLALEDKELGR
Sbjct: 420  YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479

Query: 446  VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505
            VIL+PT NS K +E H+M V KN  D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW
Sbjct: 480  VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539

Query: 506  KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565
            KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG  FFNAVKEG
Sbjct: 540  KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599

Query: 566  DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADAQLSGKDADR 624
            DTVIFASDDEQDRILWVQAMYRATGQS+KPVP  Q QKLN KGG +   DA +S   ADR
Sbjct: 600  DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659

Query: 625  FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 684
             QKHGMDEFIS+NPC  DHA LF ++QR TLDHRLNDSYSCLGWFSPGQVFVLDEYCAR 
Sbjct: 660  AQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARN 719

Query: 685  GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 744
            GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF
Sbjct: 720  GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 779

Query: 745  EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 804
            EEIKERL  LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R
Sbjct: 780  EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 839

Query: 805  KCLEKAALINYTRLTEYAKIEETMNQ------------------------ASPARKLEEI 840
            KCLE+AAL+NY+RL+EYAKIE    +                         +PA+KLE+ 
Sbjct: 840  KCLEQAALVNYSRLSEYAKIEGKKREMYEHPVFCLASQVMDLTIQNVGRLITPAKKLEDT 899

Query: 841  LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900
            + LAEL IEVLQQNEEHHA   EAFAWW DL+ EHAE F +LF VDMD ALE QP D+WD
Sbjct: 900  IRLAELVIEVLQQNEEHHA---EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWD 956

Query: 901  SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960
            SFPLFQLLN+FLR D  LCNGKFHKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+
Sbjct: 957  SFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWE 1016

Query: 961  PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020
            PV                                         NGS TSEDLFWKLDALQ
Sbjct: 1017 PV----------------------------------------NNGSGTSEDLFWKLDALQ 1036

Query: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080
             F+ DLHWPE+EF  HLEQRLKLMASDM+E+CVKRTR AFE+KLQK S++TD R+P S+C
Sbjct: 1037 TFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSIC 1096

Query: 1081 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK 1140
            TMFNV+VDAK QSTKLC+++ GQE QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+K
Sbjct: 1097 TMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAK 1156

Query: 1141 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE 1200
            LSRYDEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE
Sbjct: 1157 LSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIE 1216

Query: 1201 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY 1260
            +LFDQWY+SSM VIC WLTDR+DLQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY
Sbjct: 1217 RLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTY 1276

Query: 1261 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEE 1295
            +T+  RLTVEEATASVSEGGGLQGI+MKDSDEE+E
Sbjct: 1277 ETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDE 1311


>gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo
            sapiens]
          Length = 1274

 Score = 1934 bits (5010), Expect = 0.0
 Identities = 984/1332 (73%), Positives = 1109/1332 (83%), Gaps = 98/1332 (7%)

Query: 1    MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51
            MLDPSSSEEESDE +EEES ++VL +A S  R  P+ T EG   + G  GGG        
Sbjct: 1    MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60

Query: 52   ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86
                                    G  R  SPSPSV+SE  ++E +R   +E+ER+ RLQ
Sbjct: 61   AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120

Query: 87   LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146
            LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV
Sbjct: 121  LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180

Query: 147  RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206
            +SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK
Sbjct: 181  QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240

Query: 207  YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266
            +DAIYRGEED  KQ  RM  SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN 
Sbjct: 241  FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300

Query: 267  DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326
            DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS
Sbjct: 301  DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360

Query: 327  KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386
            KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV
Sbjct: 361  KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419

Query: 387  YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445
            YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH  P VKVKLFTESTGVLALEDKELGR
Sbjct: 420  YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479

Query: 446  VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505
            VIL+PT NS K +E H+M V KN  D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW
Sbjct: 480  VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539

Query: 506  KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565
            KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG  FFNAVKEG
Sbjct: 540  KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599

Query: 566  DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADAQLSGKDADR 624
            DTVIFASDDEQDRILWVQAMYRATGQS+KPVP  Q QKLN KGG +   DA +S   ADR
Sbjct: 600  DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659

Query: 625  FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 684
             QKHGMDEFIS+NPC  DHA LF                  +GWFSPGQVFVLDEYCAR 
Sbjct: 660  AQKHGMDEFISSNPCNFDHASLFE-----------------MGWFSPGQVFVLDEYCARN 702

Query: 685  GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 744
            GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF
Sbjct: 703  GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 762

Query: 745  EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 804
            EEIKERL  LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R
Sbjct: 763  EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 822

Query: 805  KCLEKAALINYTRLTEYAKIEETMNQ-ASPARKLEEILHLAELCIEVLQQNEEHHAEGRE 863
            KCLE+AAL+NY+RL+EYAKIEE + +  +PA+KLE+ + LAEL IEVLQQNEEHHA   E
Sbjct: 823  KCLEQAALVNYSRLSEYAKIEENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHA---E 879

Query: 864  AFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKF 923
            AFAWW DL+ EHAE F +LF VDMD ALE QP D+WDSFPLFQLLN+FLR D  LCNGKF
Sbjct: 880  AFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKF 939

Query: 924  HKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLN 983
            HKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PV                     
Sbjct: 940  HKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPV--------------------- 978

Query: 984  LPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKL 1043
                                NGS TSEDLFWKLDALQ F+ DLHWPE+EF  HLEQRLKL
Sbjct: 979  -------------------NNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKL 1019

Query: 1044 MASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQ 1103
            MASDM+E+CVKRTR AFE+KLQK S++TD R+P S+CTMFNV+VDAK QSTKLC+++ GQ
Sbjct: 1020 MASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQ 1079

Query: 1104 EQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAK 1163
            E QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+KLSRYDEGT FSS LSFTVKAA+K
Sbjct: 1080 EHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASK 1139

Query: 1164 YVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLD 1223
            YVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE+LFDQWY+SSM VIC WLTDR+D
Sbjct: 1140 YVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMD 1199

Query: 1224 LQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQ 1283
            LQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY+T+  RLTVEEATASVSEGGGLQ
Sbjct: 1200 LQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQ 1259

Query: 1284 GITMKDSDEEEE 1295
            GI+MKDSDEE+E
Sbjct: 1260 GISMKDSDEEDE 1271


>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
          Length = 1591

 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 59/241 (24%), Positives = 103/241 (42%), Gaps = 19/241 (7%)

Query: 676  VLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLLHYSFAFCASHVHGNRPDGI 733
            ++DE+  RYG+   ++ + + A L        V  +  TLL    A+ A           
Sbjct: 785  IVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 844

Query: 734  GTVSVEE--KERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKATLSLLE-----R 784
               +     KERF ++ ++L + L   +S +R  FP G PE    LK+T+ LL      R
Sbjct: 845  DRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFR 904

Query: 785  VLMKDIATPIPAEE-VKKVVRKCLEKA--ALIN-----YTRLTEYAKIEETMNQASPARK 836
            + ++++ +P  A + VK  V+ CL      + N     Y+R  +  +      Q    R 
Sbjct: 905  MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRN 964

Query: 837  LEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQ 896
            L+    L  L + ++++++  +      F    ++    AE  W LF  DM  ALE   +
Sbjct: 965  LDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEK 1024

Query: 897  D 897
            D
Sbjct: 1025 D 1025


>gi|122937247 unc-13 homolog A [Homo sapiens]
          Length = 1791

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 70/311 (22%), Positives = 127/311 (40%), Gaps = 29/311 (9%)

Query: 676  VLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLLHYSFAFCASHVHGNRPDGI 733
            ++DE+  RYGV   ++ + + A L        V  +  TLL    A+ A           
Sbjct: 949  IVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 1008

Query: 734  GTVSVEE--KERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKATLSLLE-----R 784
               +     KERF ++ ++L + L   +S +R  FP   PE    LK+T+ LL      R
Sbjct: 1009 DRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFR 1068

Query: 785  VLMKDIATPIPAEE-VKKVVRKCLEKA---------ALINYTRLTEYAKIEETM--NQAS 832
            + ++++ +P  A + VK  V+ CL             L +    T+ AK  E +   Q  
Sbjct: 1069 MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGP 1128

Query: 833  PARKLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALE 892
              + L+    L  L + ++++++  +      F    ++    AE  W LF  DM  A+E
Sbjct: 1129 SIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAME 1188

Query: 893  AQPQDSWDSFPLFQLLN---NFLRNDTLLCNGKFHKHLQEI---FVPLVVRYVDLMESSI 946
               +        +  L+    +L N+ +     F   + E    F P V++++D  E   
Sbjct: 1189 EHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVS 1248

Query: 947  AQSIHRGFEQE 957
               +H   E++
Sbjct: 1249 RDFLHGALERD 1259


>gi|122937514 unc-13 homolog C [Homo sapiens]
          Length = 2214

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 57/249 (22%), Positives = 111/249 (44%), Gaps = 25/249 (10%)

Query: 668  WFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLL-----HYSFAF 720
            +F      ++DE+  RYG+   ++ + + + L        V  +  TLL      Y+   
Sbjct: 1397 FFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTT 1456

Query: 721  CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKAT 778
             ++++  +  D     +   +E+F ++ ++L + L   +S +R  FP    E    LK+T
Sbjct: 1457 VSTNIQVSASDRFAATNFG-REKFIKLLDQLHNSLRIDLSKYRENFPASNTERLQDLKST 1515

Query: 779  LSLLE-----RVLMKDIATPIPAEEV-KKVVRKCLE---KAALIN----YTRLTEYAKIE 825
            + LL      R+ + ++ +P  A  V K  VR CL+   K    N    Y++LT+ +K +
Sbjct: 1516 VDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDSTYKYIFDNCHELYSQLTDPSKKQ 1575

Query: 826  ETM--NQASPARKLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALF 883
            +    +Q    + L+    L  L + ++ +++  +      F    ++    AE  W LF
Sbjct: 1576 DIPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQELNMGKISAEIMWTLF 1635

Query: 884  TVDMDTALE 892
             +DM  ALE
Sbjct: 1636 ALDMKYALE 1644


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 58/263 (22%), Positives = 113/263 (42%), Gaps = 19/263 (7%)

Query: 72   QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
            + Q ++EQE +  LQ  +         +  K  TD  +R ++L + + +L +   +A   
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA--- 1403

Query: 132  GETQIVADEAFCNAVRSYYEVFLKS--DRVARMVQSGG-CSAND-----FREVFKKNIEK 183
             E  + A  A C ++    +       D +  + +S   C+A D     F +V  +  +K
Sbjct: 1404 -EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQK 1462

Query: 184  RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242
               +  E++   KE+  LS+ + K   +Y    D  +   R   +   E+    EQ+ E 
Sbjct: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEG 1522

Query: 243  FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299
             +QI  ++K++ Q+    C++  A E+A       +G   R+QL     K     K   K
Sbjct: 1523 GKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1582

Query: 300  DMENMYIEELRSSVNLLMANLES 322
            D E   I++L+ +   ++  ++S
Sbjct: 1583 DEE---IDQLKRNHTRVVETMQS 1602



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 20/131 (15%)

Query: 225  ALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLA 284
            A SA  EL   +E  ++  ++ L    L+H+ +  A +  +AD   A++  ++D   ++ 
Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSM-AELGEQIDNLQRVK 1217

Query: 285  DKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSA 344
             K+ KE+                EL+   + L +N E++  +KG     L+K+ RS    
Sbjct: 1218 QKLEKEK---------------SELKMETDDLSSNAEAISKAKG----NLEKMCRSLEDQ 1258

Query: 345  FLDIGDENEIQ 355
              ++  + E Q
Sbjct: 1259 VSELKTKEEEQ 1269


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 25/297 (8%)

Query: 72   QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
            + Q ++EQE +  LQ  +         +  K  TD  +R ++L + + +L  +R QA   
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQA--- 1405

Query: 132  GETQIVADEAFCNAVRS--------YYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEK 183
             E  + A  A C ++            ++ L  +R      +      +F ++  +  +K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465

Query: 184  RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242
               +  E++   KE   L + + K    Y    D  +   R   +   E+    EQ+ E 
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525

Query: 243  FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299
             ++I  ++K++ Q+    C+L  A E+A       +G   R+QL     K     K   K
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585

Query: 300  DMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356
            D E   I++L+ +   ++ +++S   ++        +LK+         GD NE+++
Sbjct: 1586 DEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1633


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 25/297 (8%)

Query: 72   QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
            + Q ++EQE +  LQ  +         +  K  TD  +R ++L + + +L  +R QA   
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQA--- 1405

Query: 132  GETQIVADEAFCNAVRS--------YYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEK 183
             E  + A  A C ++            ++ L  +R      +      +F ++  +  +K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465

Query: 184  RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242
               +  E++   KE   L + + K    Y    D  +   R   +   E+    EQ+ E 
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525

Query: 243  FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299
             ++I  ++K++ Q+    C+L  A E+A       +G   R+QL     K     K   K
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585

Query: 300  DMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356
            D E   I++L+ +   ++ +++S   ++        +LK+         GD NE+++
Sbjct: 1586 DEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1633


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 38.5 bits (88), Expect = 0.042
 Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 16/167 (9%)

Query: 172 DFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSE 231
           DF +   K++EKR+R L E    +KETV S  +     +    E LC++   +   A  +
Sbjct: 278 DFLQQANKDLEKRIRELME----TKETVTSEVV----NLSNKNEKLCQELTEIDQLA-QQ 328

Query: 232 LILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKER 291
           L   KE++ E   + LG  K E  +     ++ + +E  A+++ EL+    L  K  KER
Sbjct: 329 LERHKEEVLETADKELGEAKKE--IKRKLSEMQDLEETMAKLQLELN----LCQK-EKER 381

Query: 292 KFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLK 338
              + + K      + +L      L   +ES  V++     ++++++
Sbjct: 382 LSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERMR 428


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 38.1 bits (87), Expect = 0.055
 Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 9/130 (6%)

Query: 19  SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
           SR +LV   + + +PPAP+   RR   D     G G  +  VSP   +LS GR +  +  
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648

Query: 74  ---QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFL 130
               +  EQ+RR  ++L    +  +    +A+    +++        +  L+ ++ +A L
Sbjct: 649 RITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGL 708

Query: 131 NGETQIVADE 140
             E Q + DE
Sbjct: 709 QEEAQQLRDE 718


>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
          Length = 731

 Score = 38.1 bits (87), Expect = 0.055
 Identities = 68/290 (23%), Positives = 122/290 (42%), Gaps = 44/290 (15%)

Query: 109 RRQQKLNKQQLQLLKERFQAFLNG---ETQIVADEAFCNAVRSYYEVFLKSDRVARMV-- 163
           +R+Q+  KQ    ++  F A LN    E Q +A EA   A R Y +   + D + + V  
Sbjct: 362 KREQESYKQ----MQSEFAARLNKVEMERQNLA-EAITLAERKYSDEKKRVDELQQQVKL 416

Query: 164 -----QSGGCSANDFREVFKKNI---EKRVRSLPE---IDGLSKETVLSSWIA--KYDAI 210
                +S      D+++   + +   EK + SL E    +GL   T  S  +   +++  
Sbjct: 417 YKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTASSMELEELRHEKE 476

Query: 211 YRGEE---------DLCKQPNRMALSAVSELILSKEQLYEMFQQILGIK----KLEHQLL 257
            + EE          L  +   M    V+E   ++EQL ++  QI G K    +LE +L 
Sbjct: 477 MQREEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELE 536

Query: 258 YNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLM 317
               +    +E   + +  L  R++  D+  ++ +  +   K + N    EL + ++ L 
Sbjct: 537 RLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLR-NQLTNKTLSNSSQSELENRLHQLT 595

Query: 318 ANL-------ESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
             L       ESL   K    F+L++L++  NSA     + + I +S  D
Sbjct: 596 ETLIQKQTMLESLSTEKNSLVFQLERLEQQMNSASGSSSNGSSINMSGID 645


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 37.4 bits (85), Expect = 0.094
 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 11/132 (8%)

Query: 19  SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
           SR +LV   + + +PPAP+   RR   D     G G  +  VSP   +LS GR +  +  
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648

Query: 74  -----QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQA 128
                 +  EQ+RR  ++L    +  +    +A+    +++        +  L+ ++ +A
Sbjct: 649 NRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERA 708

Query: 129 FLNGETQIVADE 140
            L  E Q + DE
Sbjct: 709 GLQEEAQQLRDE 720


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 10/121 (8%)

Query: 19  SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
           SR +LV   + + +PPAP+   RR   D     G G  +  VSP   +LS GR +  +  
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648

Query: 74  ---QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFL 130
               +  EQ+RR  ++L    +  +    +A QP+   R   +   QQL+   E   A +
Sbjct: 649 RITHISAEQKRRFNIKLGFDTLHGLVSTLSA-QPSLKERAGLQEEAQQLRDEIEELNAAI 707

Query: 131 N 131
           N
Sbjct: 708 N 708


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 61/298 (20%), Positives = 126/298 (42%), Gaps = 27/298 (9%)

Query: 72   QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
            + Q ++EQE +  LQ  +         +  K  TD  +R ++L + + +L     Q   +
Sbjct: 1348 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQD 1403

Query: 132  GETQIVADEAFCNAVRSYYEVFLKSDRVARMVQ----SGGCSAND-----FREVFKKNIE 182
             E  + A  A C ++    +  L+++    M+     +  C+A D     F ++  +  +
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQR-LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462

Query: 183  KRVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYE 241
            K   +  E++   KE+  LS+ + K    Y    D  +   R   +   E+    EQ+ E
Sbjct: 1463 KCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1522

Query: 242  MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIA 298
              ++I  ++K++ Q+     +L  A E+A       +G   R+QL     K     K   
Sbjct: 1523 GGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1582

Query: 299  KDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356
            KD E   I++++ +   ++ +++S   ++        +LK+         GD NE+++
Sbjct: 1583 KDEE---IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1631


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 35.8 bits (81), Expect = 0.27
 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 12/123 (9%)

Query: 19  SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
           SR +LV   + + +PPAP+   RR   D     G G  +  VSP   +LS GR +  +  
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648

Query: 74  -----QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQA 128
                 +  EQ+RR  ++L    +  +    +A QP+   R   +   QQL+   E   A
Sbjct: 649 NRRITHISAEQKRRFNIKLGFDTLHGLVSTLSA-QPSLKERAGLQEEAQQLRDEIEELNA 707

Query: 129 FLN 131
            +N
Sbjct: 708 AIN 710


>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
           3 [Homo sapiens]
          Length = 834

 Score = 35.8 bits (81), Expect = 0.27
 Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 8/121 (6%)

Query: 477 KLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELM 536
           K+   +D P+ +   GYL+      +K W +R+F  +Q SQ  +      +KK +    +
Sbjct: 258 KVEFDVDAPSGVVMEGYLFKRASNAFKTWNRRWF-SIQNSQLVY------QKKLKDALTV 310

Query: 537 QLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPV 596
            ++   +    P   ++     F  +    + +  +D E+ R  WVQA+  +   +Y+  
Sbjct: 311 VVDDLRLCSVKPCEDIERR-FCFEVLSPTKSCMLQADSEKLRQAWVQAVQASIASAYRES 369

Query: 597 P 597
           P
Sbjct: 370 P 370


>gi|4758968 cytohesin 3 [Homo sapiens]
          Length = 399

 Score = 35.8 bits (81), Expect = 0.27
 Identities = 66/320 (20%), Positives = 132/320 (41%), Gaps = 35/320 (10%)

Query: 244 QQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMEN 303
           +++L I++ + +L+ +   ++    + A++  E+D    + +    +R     + +   N
Sbjct: 22  EELLDIRRRKKELIDD---IERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFN 78

Query: 304 MYIEELRSSVNLLMAN--LESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDV 361
           M   + +  +  L+ N  L+S P       +K + L ++    +L   DE  I++ ++ V
Sbjct: 79  M---DPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFV 135

Query: 362 VLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTD---QAEASRPQWGTQGDFTTT 418
            L         E   L  V   R    +  + GE  + D   +A ASR      G F +T
Sbjct: 136 ELH--------EFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQST 187

Query: 419 HPRPVVKVKLFTESTGVLA--LEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKI 476
               V+   +   +T +    + DK      +      ++  +L   ++ +N  +S    
Sbjct: 188 DTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELL-RNLYESIKNE 246

Query: 477 KLAVRMDKPAHMKHS-------GYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKK 529
              +  D    + H+       G+L  LG +V K WK+R+F+L     Y F    Y   K
Sbjct: 247 PFKIPEDDGNDLTHTFFNPDREGWLLKLGGRV-KTWKRRWFILTDNCLYYF---EYTTDK 302

Query: 530 SEPQELMQLEGYTV-DYTDP 548
            EP+ ++ LE  ++ +  DP
Sbjct: 303 -EPRGIIPLENLSIREVEDP 321


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 11/162 (6%)

Query: 172 DFREVFKKNIEKRVRSLPEIDGLSKETV---LSSWIAKYDAIYRGEEDLCKQPNRMALSA 228
           DF + +K  +E+  R   EI  LSKE      S    K +  Y+ +E   ++  R     
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE--LQEKTREVQER 885

Query: 229 VSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMA 288
           ++E+   KEQL E     L   + E  L+    +L    E+   + +E D   QL + + 
Sbjct: 886 LNEMEQLKEQL-ENRDSTLQTVEREKTLITE--KLQQTLEEVKTLTQEKDDLKQLQESLQ 942

Query: 289 KERKFPKFIAKDMENMYI---EELRSSVNLLMANLESLPVSK 327
            ER   K    D  NM I   E+LR+++  L  + E++   K
Sbjct: 943 IERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 984


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 8/126 (6%)

Query: 219  KQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELD 278
            +Q  R    A  EL+ + E+L  +  Q  G+   + +L  +  QL    E+AAQ RRE +
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1801

Query: 279  GRLQL----ADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS--KGGPEF 332
             + +     A  MA+E K  +  +  +E M  + L  +V  L A LE    +  +GG + 
Sbjct: 1802 EKAKKAITDAAMMAEELKKEQDTSAHLERMK-KTLEQTVRELQARLEEAEQAALRGGKK- 1859

Query: 333  KLQKLK 338
            ++QKL+
Sbjct: 1860 QVQKLE 1865


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 35.0 bits (79), Expect = 0.47
 Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%)

Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234
           F   IEK    L E +   ++KE +L   ++KY+ I+  E  + K+     +  + +L +
Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567

Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283
           +      K +  E    I+  ++ E  LL N   L   D          +++EL    QL
Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624

Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342
            D+ +K+ K      K++EN  YI + ++  +LL+   + L       +  ++K +  Q 
Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682

Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398
           +      D +   +++     D+   F   + I+   G +++     +   +    EK+Q
Sbjct: 683 ALMHTSNDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742

Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458
                            +T     +  ++L  E    + L  K+  R +L  TS   K+ 
Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786

Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493
           +L  +V+P  + +  L I   + ++    + +S +
Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 35.0 bits (79), Expect = 0.47
 Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%)

Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234
           F   IEK    L E +   ++KE +L   ++KY+ I+  E  + K+     +  + +L +
Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567

Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283
           +      K +  E    I+  ++ E  LL N   L   D          +++EL    QL
Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624

Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342
            D+ +K+ K      K++EN  YI + ++  +LL+   + L       +  ++K +  Q 
Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682

Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398
           +      D +   +++     D+   F   + I+   G +++     +   +    EK+Q
Sbjct: 683 ALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742

Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458
                            +T     +  ++L  E    + L  K+  R +L  TS   K+ 
Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786

Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493
           +L  +V+P  + +  L I   + ++    + +S +
Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 35.0 bits (79), Expect = 0.47
 Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%)

Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234
           F   IEK    L E +   ++KE +L   ++KY+ I+  E  + K+     +  + +L +
Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567

Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283
           +      K +  E    I+  ++ E  LL N   L   D          +++EL    QL
Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624

Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342
            D+ +K+ K      K++EN  YI + ++  +LL+   + L       +  ++K +  Q 
Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682

Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398
           +      D +   +++     D+   F   + I+   G +++     +   +    EK+Q
Sbjct: 683 ALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742

Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458
                            +T     +  ++L  E    + L  K+  R +L  TS   K+ 
Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786

Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493
           +L  +V+P  + +  L I   + ++    + +S +
Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 35.0 bits (79), Expect = 0.47
 Identities = 64/305 (20%), Positives = 126/305 (41%), Gaps = 35/305 (11%)

Query: 72   QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
            + Q ++E E +  LQ  +         +  K  TD  +R ++L + + +L     Q   +
Sbjct: 1346 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQD 1401

Query: 132  GETQIVADEAFCNAVRSYYEVFLKS--DRVARMVQSGGCSA------NDFREVFKKNIEK 183
             E  + A  A C+++            D +  + +S   +A       +F ++  +  +K
Sbjct: 1402 AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQK 1461

Query: 184  RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDL-----CKQPNRMALSAVSELILSKE 237
               S  E++   KE   LS+ + K    Y  EE L      K+ N+     +S+L    E
Sbjct: 1462 YEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENKNLQEEISDLT---E 1516

Query: 238  QLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFP 294
            QL E  + +  ++K+  QL     +L +A E+A       +G   R QL     K     
Sbjct: 1517 QLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER 1576

Query: 295  KFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEI 354
            K   KD E   +E+ + +   ++ +L++   ++     ++ ++K+         GD NE+
Sbjct: 1577 KLAEKDEE---MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME------GDLNEM 1627

Query: 355  QLSKS 359
            ++  S
Sbjct: 1628 EIQLS 1632


>gi|5174457 kinetochore associated 2 [Homo sapiens]
          Length = 642

 Score = 34.7 bits (78), Expect = 0.61
 Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 9/187 (4%)

Query: 157 DRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEED 216
           D   +  +S    A+ F E+    ++ +++ L  +D    E++ +   A  + I R E++
Sbjct: 227 DYTIKCYESFMSGADSFDEM-NAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQE 285

Query: 217 LCKQPNRM-ALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRR 275
             K+PNR+ +L  +   +    Q Y+ +     +  LE        +L+  +E+ A++  
Sbjct: 286 REKEPNRLESLRKLKASLQGDVQKYQAY-----MSNLESHSAILDQKLNGLNEEIARVEL 340

Query: 276 ELDGRLQLADKMAKERKFPKFIAKDMENMYIE--ELRSSVNLLMANLESLPVSKGGPEFK 333
           E +   Q   ++       K+   D+E +  E  EL+ ++N L  +LE+        E K
Sbjct: 341 ECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELK 400

Query: 334 LQKLKRS 340
             + K +
Sbjct: 401 YARGKEA 407


>gi|33946313 ninein isoform 4 [Homo sapiens]
          Length = 2096

 Score = 34.7 bits (78), Expect = 0.61
 Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%)

Query: 100  NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154
            N K  T+++R QQ+L K +  L     L E    F     +        N  +    V  
Sbjct: 1087 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1146

Query: 155  K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208
            +       D   R + S G S+   +EV  +  E  V    E++  S+ET   SW  K +
Sbjct: 1147 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1204

Query: 209  AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258
             I + +E L      C + +      + ++ + K++L +M ++I      +++LLY    
Sbjct: 1205 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1262

Query: 259  --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308
              N C       ++   ++A +  +EL   + +L D++ K E     F++ +     ++ 
Sbjct: 1263 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1322

Query: 309  LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363
                +N+L+  L+           K++KL+ S     +    +   EN EI+   + + L
Sbjct: 1323 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1372

Query: 364  SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
            + TLE  +  V+ +  V    I  C  E   +EG     ++ +A    W   G   T   
Sbjct: 1373 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1427

Query: 421  RPVVKVK-LFTESTGVLALEDK 441
            RP V+ + +  E+T +L  +DK
Sbjct: 1428 RPRVQNQVILEENTTLLGFQDK 1449


>gi|33946321 ninein isoform 5 [Homo sapiens]
          Length = 2090

 Score = 34.7 bits (78), Expect = 0.61
 Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%)

Query: 100  NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154
            N K  T+++R QQ+L K +  L     L E    F     +        N  +    V  
Sbjct: 1081 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1140

Query: 155  K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208
            +       D   R + S G S+   +EV  +  E  V    E++  S+ET   SW  K +
Sbjct: 1141 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1198

Query: 209  AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258
             I + +E L      C + +      + ++ + K++L +M ++I      +++LLY    
Sbjct: 1199 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1256

Query: 259  --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308
              N C       ++   ++A +  +EL   + +L D++ K E     F++ +     ++ 
Sbjct: 1257 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1316

Query: 309  LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363
                +N+L+  L+           K++KL+ S     +    +   EN EI+   + + L
Sbjct: 1317 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1366

Query: 364  SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
            + TLE  +  V+ +  V    I  C  E   +EG     ++ +A    W   G   T   
Sbjct: 1367 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1421

Query: 421  RPVVKVK-LFTESTGVLALEDK 441
            RP V+ + +  E+T +L  +DK
Sbjct: 1422 RPRVQNQVILEENTTLLGFQDK 1443


>gi|148536871 ninein isoform 1 [Homo sapiens]
          Length = 2046

 Score = 34.7 bits (78), Expect = 0.61
 Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%)

Query: 100  NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154
            N K  T+++R QQ+L K +  L     L E    F     +        N  +    V  
Sbjct: 1081 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1140

Query: 155  K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208
            +       D   R + S G S+   +EV  +  E  V    E++  S+ET   SW  K +
Sbjct: 1141 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1198

Query: 209  AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258
             I + +E L      C + +      + ++ + K++L +M ++I      +++LLY    
Sbjct: 1199 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1256

Query: 259  --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308
              N C       ++   ++A +  +EL   + +L D++ K E     F++ +     ++ 
Sbjct: 1257 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1316

Query: 309  LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363
                +N+L+  L+           K++KL+ S     +    +   EN EI+   + + L
Sbjct: 1317 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1366

Query: 364  SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
            + TLE  +  V+ +  V    I  C  E   +EG     ++ +A    W   G   T   
Sbjct: 1367 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1421

Query: 421  RPVVKVK-LFTESTGVLALEDK 441
            RP V+ + +  E+T +L  +DK
Sbjct: 1422 RPRVQNQVILEENTTLLGFQDK 1443


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,139,823
Number of Sequences: 37866
Number of extensions: 2181105
Number of successful extensions: 9036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 105
Number of HSP's that attempted gapping in prelim test: 8878
Number of HSP's gapped (non-prelim): 218
length of query: 1296
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1182
effective length of database: 13,930,794
effective search space: 16466198508
effective search space used: 16466198508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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