BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148839294 Ca2+-dependent activator protein for secretion 2 isoform a [Homo sapiens] (1296 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148839294 Ca2+-dependent activator protein for secretion 2 is... 2586 0.0 gi|148839284 Ca2+-dependent activator protein for secretion 2 is... 2453 0.0 gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo s... 2033 0.0 gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo s... 1963 0.0 gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo s... 1934 0.0 gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 55 6e-07 gi|122937247 unc-13 homolog A [Homo sapiens] 52 5e-06 gi|122937514 unc-13 homolog C [Homo sapiens] 48 7e-05 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 44 0.001 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.019 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.019 gi|50083279 centrosome protein 4 [Homo sapiens] 39 0.042 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 38 0.055 gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 38 0.055 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 37 0.094 gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 37 0.16 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 37 0.16 gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 36 0.27 gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 36 0.27 gi|4758968 cytohesin 3 [Homo sapiens] 36 0.27 gi|71061468 centromere protein E [Homo sapiens] 35 0.36 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 35 0.36 gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 35 0.47 gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 35 0.47 gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] 35 0.47 gi|156104908 myosin heavy chain 6 [Homo sapiens] 35 0.47 gi|5174457 kinetochore associated 2 [Homo sapiens] 35 0.61 gi|33946313 ninein isoform 4 [Homo sapiens] 35 0.61 gi|33946321 ninein isoform 5 [Homo sapiens] 35 0.61 gi|148536871 ninein isoform 1 [Homo sapiens] 35 0.61 >gi|148839294 Ca2+-dependent activator protein for secretion 2 isoform a [Homo sapiens] Length = 1296 Score = 2586 bits (6704), Expect = 0.0 Identities = 1296/1296 (100%), Positives = 1296/1296 (100%) Query: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS Sbjct: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60 Query: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ Sbjct: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120 Query: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN Sbjct: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180 Query: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY Sbjct: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240 Query: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD Sbjct: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300 Query: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD Sbjct: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360 Query: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP Sbjct: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 Query: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV Sbjct: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480 Query: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG Sbjct: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540 Query: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ Sbjct: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600 Query: 601 TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660 TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN Sbjct: 601 TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660 Query: 661 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF Sbjct: 661 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720 Query: 721 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS Sbjct: 721 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780 Query: 781 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI Sbjct: 781 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840 Query: 841 LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900 LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD Sbjct: 841 LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900 Query: 901 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ Sbjct: 901 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960 Query: 961 PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020 PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ Sbjct: 961 PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020 Query: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC Sbjct: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080 Query: 1081 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK 1140 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK Sbjct: 1081 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK 1140 Query: 1141 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE 1200 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE Sbjct: 1141 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE 1200 Query: 1201 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY 1260 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY Sbjct: 1201 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY 1260 Query: 1261 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG Sbjct: 1261 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296 >gi|148839284 Ca2+-dependent activator protein for secretion 2 isoform b [Homo sapiens] Length = 1255 Score = 2453 bits (6358), Expect = 0.0 Identities = 1248/1301 (95%), Positives = 1248/1301 (95%), Gaps = 51/1301 (3%) Query: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS Sbjct: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60 Query: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ Sbjct: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120 Query: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN Sbjct: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180 Query: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY Sbjct: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240 Query: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD Sbjct: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300 Query: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD Sbjct: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360 Query: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP Sbjct: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 Query: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV Sbjct: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480 Query: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG Sbjct: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540 Query: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ Sbjct: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600 Query: 601 TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660 TQKLNPKGGTLHADAQL ADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN Sbjct: 601 TQKLNPKGGTLHADAQLY---ADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 657 Query: 661 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF Sbjct: 658 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 717 Query: 721 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS Sbjct: 718 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 777 Query: 781 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI Sbjct: 778 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 837 Query: 841 LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900 LHLAELCIEVLQQNEEHHA EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD Sbjct: 838 LHLAELCIEVLQQNEEHHA---EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 894 Query: 901 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ Sbjct: 895 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 954 Query: 961 PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020 PV NGSATSEDLFWKLDALQ Sbjct: 955 PV----------------------------------------NNGSATSEDLFWKLDALQ 974 Query: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC Sbjct: 975 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1034 Query: 1081 TMFNVLVDAKKQSTKLCALDGGQE-----QQYHSKIDDLIDNSVKEIISLLVSKFVSVLE 1135 TMFNVLVDAKKQSTKLCALDGGQE QQYHSKIDDLIDNSVKEIISLLVSKFVSVLE Sbjct: 1035 TMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLE 1094 Query: 1136 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE 1195 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE Sbjct: 1095 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE 1154 Query: 1196 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL 1255 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL Sbjct: 1155 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL 1214 Query: 1256 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG Sbjct: 1215 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1255 >gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo sapiens] Length = 1353 Score = 2033 bits (5268), Expect = 0.0 Identities = 1022/1351 (75%), Positives = 1158/1351 (85%), Gaps = 57/1351 (4%) Query: 1 MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51 MLDPSSSEEESDE +EEES ++VL +A S R P+ T EG + G GGG Sbjct: 1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60 Query: 52 ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86 G R SPSPSV+SE ++E +R +E+ER+ RLQ Sbjct: 61 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120 Query: 87 LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146 LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV Sbjct: 121 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180 Query: 147 RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206 +SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK Sbjct: 181 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240 Query: 207 YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266 +DAIYRGEED KQ RM SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN Sbjct: 241 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300 Query: 267 DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326 DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS Sbjct: 301 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360 Query: 327 KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386 KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV Sbjct: 361 KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419 Query: 387 YCTMEVEG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445 YCTMEVEG EKLQTDQAEAS+P WGTQGDF+TTH P VKVKLFTESTGVLALEDKELGR Sbjct: 420 YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479 Query: 446 VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505 VIL+PT NS K +E H+M V KN D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW Sbjct: 480 VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539 Query: 506 KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565 KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG FFNAVKEG Sbjct: 540 KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599 Query: 566 DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADAQLSGKDADR 624 DTVIFASDDEQDRILWVQAMYRATGQS+KPVP Q QKLN KGG + DA +S ADR Sbjct: 600 DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659 Query: 625 FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 684 QKHGMDEFIS+NPC DHA LF ++QR TLDHRLNDSYSCLGWFSPGQVFVLDEYCAR Sbjct: 660 AQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARN 719 Query: 685 GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 744 GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF Sbjct: 720 GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 779 Query: 745 EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 804 EEIKERL LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R Sbjct: 780 EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 839 Query: 805 KCLEKAALINYTRLTEYAKIEETMNQA-------SPARKLEEILHLAELCIEVLQQNEEH 857 KCLE+AAL+NY+RL+EYAKIEE A +PA+KLE+ + LAEL IEVLQQNEEH Sbjct: 840 KCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEH 899 Query: 858 HAEGR----EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLR 913 HAE EAFAWW DL+ EHAE F +LF VDMD ALE QP D+WDSFPLFQLLN+FLR Sbjct: 900 HAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLR 959 Query: 914 NDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVA 973 D LCNGKFHKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PVK++ ++LPNV Sbjct: 960 TDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVN 1019 Query: 974 LP-----KVPSLPLNLP----QIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVF 1024 LP KVP+LP+N+P Q+P S SWM ++Y++ NGS TSEDLFWKLDALQ F+ Sbjct: 1020 LPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIR 1079 Query: 1025 DLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFN 1084 DLHWPE+EF HLEQRLKLMASDM+E+CVKRTR AFE+KLQK S++TD R+P S+CTMFN Sbjct: 1080 DLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFN 1139 Query: 1085 VLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRY 1144 V+VDAK QSTKLC+++ GQE QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+KLSRY Sbjct: 1140 VMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRY 1199 Query: 1145 DEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFD 1204 DEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE+LFD Sbjct: 1200 DEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFD 1259 Query: 1205 QWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVH 1264 QWY+SSM VIC WLTDR+DLQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY+T+ Sbjct: 1260 QWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIR 1319 Query: 1265 RRLTVEEATASVSEGGGLQGITMKDSDEEEE 1295 RLTVEEATASVSEGGGLQGI+MKDSDEE+E Sbjct: 1320 NRLTVEEATASVSEGGGLQGISMKDSDEEDE 1350 >gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo sapiens] Length = 1314 Score = 1963 bits (5086), Expect = 0.0 Identities = 998/1355 (73%), Positives = 1123/1355 (82%), Gaps = 104/1355 (7%) Query: 1 MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51 MLDPSSSEEESDE +EEES ++VL +A S R P+ T EG + G GGG Sbjct: 1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60 Query: 52 ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86 G R SPSPSV+SE ++E +R +E+ER+ RLQ Sbjct: 61 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120 Query: 87 LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146 LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV Sbjct: 121 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180 Query: 147 RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206 +SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK Sbjct: 181 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240 Query: 207 YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266 +DAIYRGEED KQ RM SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN Sbjct: 241 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300 Query: 267 DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326 DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS Sbjct: 301 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360 Query: 327 KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386 KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV Sbjct: 361 KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419 Query: 387 YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445 YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH P VKVKLFTESTGVLALEDKELGR Sbjct: 420 YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479 Query: 446 VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505 VIL+PT NS K +E H+M V KN D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW Sbjct: 480 VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539 Query: 506 KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565 KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG FFNAVKEG Sbjct: 540 KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599 Query: 566 DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADAQLSGKDADR 624 DTVIFASDDEQDRILWVQAMYRATGQS+KPVP Q QKLN KGG + DA +S ADR Sbjct: 600 DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659 Query: 625 FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 684 QKHGMDEFIS+NPC DHA LF ++QR TLDHRLNDSYSCLGWFSPGQVFVLDEYCAR Sbjct: 660 AQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARN 719 Query: 685 GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 744 GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF Sbjct: 720 GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 779 Query: 745 EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 804 EEIKERL LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R Sbjct: 780 EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 839 Query: 805 KCLEKAALINYTRLTEYAKIEETMNQ------------------------ASPARKLEEI 840 KCLE+AAL+NY+RL+EYAKIE + +PA+KLE+ Sbjct: 840 KCLEQAALVNYSRLSEYAKIEGKKREMYEHPVFCLASQVMDLTIQNVGRLITPAKKLEDT 899 Query: 841 LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900 + LAEL IEVLQQNEEHHA EAFAWW DL+ EHAE F +LF VDMD ALE QP D+WD Sbjct: 900 IRLAELVIEVLQQNEEHHA---EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWD 956 Query: 901 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960 SFPLFQLLN+FLR D LCNGKFHKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+ Sbjct: 957 SFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWE 1016 Query: 961 PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020 PV NGS TSEDLFWKLDALQ Sbjct: 1017 PV----------------------------------------NNGSGTSEDLFWKLDALQ 1036 Query: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080 F+ DLHWPE+EF HLEQRLKLMASDM+E+CVKRTR AFE+KLQK S++TD R+P S+C Sbjct: 1037 TFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSIC 1096 Query: 1081 TMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSK 1140 TMFNV+VDAK QSTKLC+++ GQE QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+K Sbjct: 1097 TMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAK 1156 Query: 1141 LSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIE 1200 LSRYDEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE Sbjct: 1157 LSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIE 1216 Query: 1201 KLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTY 1260 +LFDQWY+SSM VIC WLTDR+DLQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY Sbjct: 1217 RLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTY 1276 Query: 1261 DTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEE 1295 +T+ RLTVEEATASVSEGGGLQGI+MKDSDEE+E Sbjct: 1277 ETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDE 1311 >gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo sapiens] Length = 1274 Score = 1934 bits (5010), Expect = 0.0 Identities = 984/1332 (73%), Positives = 1109/1332 (83%), Gaps = 98/1332 (7%) Query: 1 MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51 MLDPSSSEEESDE +EEES ++VL +A S R P+ T EG + G GGG Sbjct: 1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60 Query: 52 ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86 G R SPSPSV+SE ++E +R +E+ER+ RLQ Sbjct: 61 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120 Query: 87 LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146 LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV Sbjct: 121 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180 Query: 147 RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206 +SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK Sbjct: 181 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240 Query: 207 YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266 +DAIYRGEED KQ RM SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN Sbjct: 241 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300 Query: 267 DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326 DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS Sbjct: 301 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360 Query: 327 KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386 KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV Sbjct: 361 KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419 Query: 387 YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445 YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH P VKVKLFTESTGVLALEDKELGR Sbjct: 420 YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479 Query: 446 VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505 VIL+PT NS K +E H+M V KN D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW Sbjct: 480 VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539 Query: 506 KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565 KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG FFNAVKEG Sbjct: 540 KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599 Query: 566 DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADAQLSGKDADR 624 DTVIFASDDEQDRILWVQAMYRATGQS+KPVP Q QKLN KGG + DA +S ADR Sbjct: 600 DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659 Query: 625 FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 684 QKHGMDEFIS+NPC DHA LF +GWFSPGQVFVLDEYCAR Sbjct: 660 AQKHGMDEFISSNPCNFDHASLFE-----------------MGWFSPGQVFVLDEYCARN 702 Query: 685 GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 744 GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF Sbjct: 703 GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 762 Query: 745 EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 804 EEIKERL LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R Sbjct: 763 EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 822 Query: 805 KCLEKAALINYTRLTEYAKIEETMNQ-ASPARKLEEILHLAELCIEVLQQNEEHHAEGRE 863 KCLE+AAL+NY+RL+EYAKIEE + + +PA+KLE+ + LAEL IEVLQQNEEHHA E Sbjct: 823 KCLEQAALVNYSRLSEYAKIEENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHA---E 879 Query: 864 AFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKF 923 AFAWW DL+ EHAE F +LF VDMD ALE QP D+WDSFPLFQLLN+FLR D LCNGKF Sbjct: 880 AFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKF 939 Query: 924 HKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLN 983 HKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PV Sbjct: 940 HKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPV--------------------- 978 Query: 984 LPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKL 1043 NGS TSEDLFWKLDALQ F+ DLHWPE+EF HLEQRLKL Sbjct: 979 -------------------NNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKL 1019 Query: 1044 MASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQ 1103 MASDM+E+CVKRTR AFE+KLQK S++TD R+P S+CTMFNV+VDAK QSTKLC+++ GQ Sbjct: 1020 MASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQ 1079 Query: 1104 EQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAK 1163 E QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+KLSRYDEGT FSS LSFTVKAA+K Sbjct: 1080 EHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASK 1139 Query: 1164 YVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLD 1223 YVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE+LFDQWY+SSM VIC WLTDR+D Sbjct: 1140 YVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMD 1199 Query: 1224 LQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQ 1283 LQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY+T+ RLTVEEATASVSEGGGLQ Sbjct: 1200 LQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQ 1259 Query: 1284 GITMKDSDEEEE 1295 GI+MKDSDEE+E Sbjct: 1260 GISMKDSDEEDE 1271 >gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] Length = 1591 Score = 54.7 bits (130), Expect = 6e-07 Identities = 59/241 (24%), Positives = 103/241 (42%), Gaps = 19/241 (7%) Query: 676 VLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLLHYSFAFCASHVHGNRPDGI 733 ++DE+ RYG+ ++ + + A L V + TLL A+ A Sbjct: 785 IVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 844 Query: 734 GTVSVEE--KERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKATLSLLE-----R 784 + KERF ++ ++L + L +S +R FP G PE LK+T+ LL R Sbjct: 845 DRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFR 904 Query: 785 VLMKDIATPIPAEE-VKKVVRKCLEKA--ALIN-----YTRLTEYAKIEETMNQASPARK 836 + ++++ +P A + VK V+ CL + N Y+R + + Q R Sbjct: 905 MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRN 964 Query: 837 LEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQ 896 L+ L L + ++++++ + F ++ AE W LF DM ALE + Sbjct: 965 LDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEK 1024 Query: 897 D 897 D Sbjct: 1025 D 1025 >gi|122937247 unc-13 homolog A [Homo sapiens] Length = 1791 Score = 51.6 bits (122), Expect = 5e-06 Identities = 70/311 (22%), Positives = 127/311 (40%), Gaps = 29/311 (9%) Query: 676 VLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLLHYSFAFCASHVHGNRPDGI 733 ++DE+ RYGV ++ + + A L V + TLL A+ A Sbjct: 949 IVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 1008 Query: 734 GTVSVEE--KERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKATLSLLE-----R 784 + KERF ++ ++L + L +S +R FP PE LK+T+ LL R Sbjct: 1009 DRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFR 1068 Query: 785 VLMKDIATPIPAEE-VKKVVRKCLEKA---------ALINYTRLTEYAKIEETM--NQAS 832 + ++++ +P A + VK V+ CL L + T+ AK E + Q Sbjct: 1069 MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGP 1128 Query: 833 PARKLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALE 892 + L+ L L + ++++++ + F ++ AE W LF DM A+E Sbjct: 1129 SIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAME 1188 Query: 893 AQPQDSWDSFPLFQLLN---NFLRNDTLLCNGKFHKHLQEI---FVPLVVRYVDLMESSI 946 + + L+ +L N+ + F + E F P V++++D E Sbjct: 1189 EHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVS 1248 Query: 947 AQSIHRGFEQE 957 +H E++ Sbjct: 1249 RDFLHGALERD 1259 >gi|122937514 unc-13 homolog C [Homo sapiens] Length = 2214 Score = 47.8 bits (112), Expect = 7e-05 Identities = 57/249 (22%), Positives = 111/249 (44%), Gaps = 25/249 (10%) Query: 668 WFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLL-----HYSFAF 720 +F ++DE+ RYG+ ++ + + + L V + TLL Y+ Sbjct: 1397 FFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTT 1456 Query: 721 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKAT 778 ++++ + D + +E+F ++ ++L + L +S +R FP E LK+T Sbjct: 1457 VSTNIQVSASDRFAATNFG-REKFIKLLDQLHNSLRIDLSKYRENFPASNTERLQDLKST 1515 Query: 779 LSLLE-----RVLMKDIATPIPAEEV-KKVVRKCLE---KAALIN----YTRLTEYAKIE 825 + LL R+ + ++ +P A V K VR CL+ K N Y++LT+ +K + Sbjct: 1516 VDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDSTYKYIFDNCHELYSQLTDPSKKQ 1575 Query: 826 ETM--NQASPARKLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALF 883 + +Q + L+ L L + ++ +++ + F ++ AE W LF Sbjct: 1576 DIPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQELNMGKISAEIMWTLF 1635 Query: 884 TVDMDTALE 892 +DM ALE Sbjct: 1636 ALDMKYALE 1644 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 43.5 bits (101), Expect = 0.001 Identities = 58/263 (22%), Positives = 113/263 (42%), Gaps = 19/263 (7%) Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131 + Q ++EQE + LQ + + K TD +R ++L + + +L + +A Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA--- 1403 Query: 132 GETQIVADEAFCNAVRSYYEVFLKS--DRVARMVQSGG-CSAND-----FREVFKKNIEK 183 E + A A C ++ + D + + +S C+A D F +V + +K Sbjct: 1404 -EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQK 1462 Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242 + E++ KE+ LS+ + K +Y D + R + E+ EQ+ E Sbjct: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEG 1522 Query: 243 FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299 +QI ++K++ Q+ C++ A E+A +G R+QL K K K Sbjct: 1523 GKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1582 Query: 300 DMENMYIEELRSSVNLLMANLES 322 D E I++L+ + ++ ++S Sbjct: 1583 DEE---IDQLKRNHTRVVETMQS 1602 Score = 32.7 bits (73), Expect = 2.3 Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 20/131 (15%) Query: 225 ALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLA 284 A SA EL +E ++ ++ L L+H+ + A + +AD A++ ++D ++ Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSM-AELGEQIDNLQRVK 1217 Query: 285 DKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSA 344 K+ KE+ EL+ + L +N E++ +KG L+K+ RS Sbjct: 1218 QKLEKEK---------------SELKMETDDLSSNAEAISKAKG----NLEKMCRSLEDQ 1258 Query: 345 FLDIGDENEIQ 355 ++ + E Q Sbjct: 1259 VSELKTKEEEQ 1269 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 39.7 bits (91), Expect = 0.019 Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 25/297 (8%) Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131 + Q ++EQE + LQ + + K TD +R ++L + + +L +R QA Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQA--- 1405 Query: 132 GETQIVADEAFCNAVRS--------YYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEK 183 E + A A C ++ ++ L +R + +F ++ + +K Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465 Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242 + E++ KE L + + K Y D + R + E+ EQ+ E Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525 Query: 243 FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299 ++I ++K++ Q+ C+L A E+A +G R+QL K K K Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585 Query: 300 DMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356 D E I++L+ + ++ +++S ++ +LK+ GD NE+++ Sbjct: 1586 DEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1633 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 39.7 bits (91), Expect = 0.019 Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 25/297 (8%) Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131 + Q ++EQE + LQ + + K TD +R ++L + + +L +R QA Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQA--- 1405 Query: 132 GETQIVADEAFCNAVRS--------YYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEK 183 E + A A C ++ ++ L +R + +F ++ + +K Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465 Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242 + E++ KE L + + K Y D + R + E+ EQ+ E Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525 Query: 243 FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299 ++I ++K++ Q+ C+L A E+A +G R+QL K K K Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585 Query: 300 DMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356 D E I++L+ + ++ +++S ++ +LK+ GD NE+++ Sbjct: 1586 DEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1633 >gi|50083279 centrosome protein 4 [Homo sapiens] Length = 1140 Score = 38.5 bits (88), Expect = 0.042 Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 16/167 (9%) Query: 172 DFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSE 231 DF + K++EKR+R L E +KETV S + + E LC++ + A + Sbjct: 278 DFLQQANKDLEKRIRELME----TKETVTSEVV----NLSNKNEKLCQELTEIDQLA-QQ 328 Query: 232 LILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKER 291 L KE++ E + LG K E + ++ + +E A+++ EL+ L K KER Sbjct: 329 LERHKEEVLETADKELGEAKKE--IKRKLSEMQDLEETMAKLQLELN----LCQK-EKER 381 Query: 292 KFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLK 338 + + K + +L L +ES V++ ++++++ Sbjct: 382 LSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERMR 428 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 38.1 bits (87), Expect = 0.055 Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 9/130 (6%) Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73 SR +LV + + +PPAP+ RR D G G + VSP +LS GR + + Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648 Query: 74 ---QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFL 130 + EQ+RR ++L + + +A+ +++ + L+ ++ +A L Sbjct: 649 RITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGL 708 Query: 131 NGETQIVADE 140 E Q + DE Sbjct: 709 QEEAQQLRDE 718 >gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] Length = 731 Score = 38.1 bits (87), Expect = 0.055 Identities = 68/290 (23%), Positives = 122/290 (42%), Gaps = 44/290 (15%) Query: 109 RRQQKLNKQQLQLLKERFQAFLNG---ETQIVADEAFCNAVRSYYEVFLKSDRVARMV-- 163 +R+Q+ KQ ++ F A LN E Q +A EA A R Y + + D + + V Sbjct: 362 KREQESYKQ----MQSEFAARLNKVEMERQNLA-EAITLAERKYSDEKKRVDELQQQVKL 416 Query: 164 -----QSGGCSANDFREVFKKNI---EKRVRSLPE---IDGLSKETVLSSWIA--KYDAI 210 +S D+++ + + EK + SL E +GL T S + +++ Sbjct: 417 YKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTASSMELEELRHEKE 476 Query: 211 YRGEE---------DLCKQPNRMALSAVSELILSKEQLYEMFQQILGIK----KLEHQLL 257 + EE L + M V+E ++EQL ++ QI G K +LE +L Sbjct: 477 MQREEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELE 536 Query: 258 YNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLM 317 + +E + + L R++ D+ ++ + + K + N EL + ++ L Sbjct: 537 RLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLR-NQLTNKTLSNSSQSELENRLHQLT 595 Query: 318 ANL-------ESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360 L ESL K F+L++L++ NSA + + I +S D Sbjct: 596 ETLIQKQTMLESLSTEKNSLVFQLERLEQQMNSASGSSSNGSSINMSGID 645 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 37.4 bits (85), Expect = 0.094 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 11/132 (8%) Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73 SR +LV + + +PPAP+ RR D G G + VSP +LS GR + + Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648 Query: 74 -----QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQA 128 + EQ+RR ++L + + +A+ +++ + L+ ++ +A Sbjct: 649 NRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERA 708 Query: 129 FLNGETQIVADE 140 L E Q + DE Sbjct: 709 GLQEEAQQLRDE 720 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 36.6 bits (83), Expect = 0.16 Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 10/121 (8%) Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73 SR +LV + + +PPAP+ RR D G G + VSP +LS GR + + Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648 Query: 74 ---QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFL 130 + EQ+RR ++L + + +A QP+ R + QQL+ E A + Sbjct: 649 RITHISAEQKRRFNIKLGFDTLHGLVSTLSA-QPSLKERAGLQEEAQQLRDEIEELNAAI 707 Query: 131 N 131 N Sbjct: 708 N 708 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 36.6 bits (83), Expect = 0.16 Identities = 61/298 (20%), Positives = 126/298 (42%), Gaps = 27/298 (9%) Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131 + Q ++EQE + LQ + + K TD +R ++L + + +L Q + Sbjct: 1348 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQD 1403 Query: 132 GETQIVADEAFCNAVRSYYEVFLKSDRVARMVQ----SGGCSAND-----FREVFKKNIE 182 E + A A C ++ + L+++ M+ + C+A D F ++ + + Sbjct: 1404 AEEHVEAVNAKCASLEKTKQR-LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462 Query: 183 KRVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYE 241 K + E++ KE+ LS+ + K Y D + R + E+ EQ+ E Sbjct: 1463 KCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1522 Query: 242 MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIA 298 ++I ++K++ Q+ +L A E+A +G R+QL K K Sbjct: 1523 GGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1582 Query: 299 KDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356 KD E I++++ + ++ +++S ++ +LK+ GD NE+++ Sbjct: 1583 KDEE---IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1631 >gi|14602435 Williams Beuren syndrome chromosome region 14 isoform beta [Homo sapiens] Length = 833 Score = 35.8 bits (81), Expect = 0.27 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 12/123 (9%) Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73 SR +LV + + +PPAP+ RR D G G + VSP +LS GR + + Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648 Query: 74 -----QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQA 128 + EQ+RR ++L + + +A QP+ R + QQL+ E A Sbjct: 649 NRRITHISAEQKRRFNIKLGFDTLHGLVSTLSA-QPSLKERAGLQEEAQQLRDEIEELNA 707 Query: 129 FLN 131 +N Sbjct: 708 AIN 710 >gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [Homo sapiens] Length = 834 Score = 35.8 bits (81), Expect = 0.27 Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 8/121 (6%) Query: 477 KLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELM 536 K+ +D P+ + GYL+ +K W +R+F +Q SQ + +KK + + Sbjct: 258 KVEFDVDAPSGVVMEGYLFKRASNAFKTWNRRWF-SIQNSQLVY------QKKLKDALTV 310 Query: 537 QLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPV 596 ++ + P ++ F + + + +D E+ R WVQA+ + +Y+ Sbjct: 311 VVDDLRLCSVKPCEDIERR-FCFEVLSPTKSCMLQADSEKLRQAWVQAVQASIASAYRES 369 Query: 597 P 597 P Sbjct: 370 P 370 >gi|4758968 cytohesin 3 [Homo sapiens] Length = 399 Score = 35.8 bits (81), Expect = 0.27 Identities = 66/320 (20%), Positives = 132/320 (41%), Gaps = 35/320 (10%) Query: 244 QQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMEN 303 +++L I++ + +L+ + ++ + A++ E+D + + +R + + N Sbjct: 22 EELLDIRRRKKELIDD---IERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFN 78 Query: 304 MYIEELRSSVNLLMAN--LESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDV 361 M + + + L+ N L+S P +K + L ++ +L DE I++ ++ V Sbjct: 79 M---DPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFV 135 Query: 362 VLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTD---QAEASRPQWGTQGDFTTT 418 L E L V R + + GE + D +A ASR G F +T Sbjct: 136 ELH--------EFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQST 187 Query: 419 HPRPVVKVKLFTESTGVLA--LEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKI 476 V+ + +T + + DK + ++ +L ++ +N +S Sbjct: 188 DTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELL-RNLYESIKNE 246 Query: 477 KLAVRMDKPAHMKHS-------GYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKK 529 + D + H+ G+L LG +V K WK+R+F+L Y F Y K Sbjct: 247 PFKIPEDDGNDLTHTFFNPDREGWLLKLGGRV-KTWKRRWFILTDNCLYYF---EYTTDK 302 Query: 530 SEPQELMQLEGYTV-DYTDP 548 EP+ ++ LE ++ + DP Sbjct: 303 -EPRGIIPLENLSIREVEDP 321 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 35.4 bits (80), Expect = 0.36 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 11/162 (6%) Query: 172 DFREVFKKNIEKRVRSLPEIDGLSKETV---LSSWIAKYDAIYRGEEDLCKQPNRMALSA 228 DF + +K +E+ R EI LSKE S K + Y+ +E ++ R Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE--LQEKTREVQER 885 Query: 229 VSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMA 288 ++E+ KEQL E L + E L+ +L E+ + +E D QL + + Sbjct: 886 LNEMEQLKEQL-ENRDSTLQTVEREKTLITE--KLQQTLEEVKTLTQEKDDLKQLQESLQ 942 Query: 289 KERKFPKFIAKDMENMYI---EELRSSVNLLMANLESLPVSK 327 ER K D NM I E+LR+++ L + E++ K Sbjct: 943 IERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 984 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 35.4 bits (80), Expect = 0.36 Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 8/126 (6%) Query: 219 KQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELD 278 +Q R A EL+ + E+L + Q G+ + +L + QL E+AAQ RRE + Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1801 Query: 279 GRLQL----ADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS--KGGPEF 332 + + A MA+E K + + +E M + L +V L A LE + +GG + Sbjct: 1802 EKAKKAITDAAMMAEELKKEQDTSAHLERMK-KTLEQTVRELQARLEEAEQAALRGGKK- 1859 Query: 333 KLQKLK 338 ++QKL+ Sbjct: 1860 QVQKLE 1865 >gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] Length = 828 Score = 35.0 bits (79), Expect = 0.47 Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%) Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234 F IEK L E + ++KE +L ++KY+ I+ E + K+ + + +L + Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567 Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283 + K + E I+ ++ E LL N L D +++EL QL Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624 Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342 D+ +K+ K K++EN YI + ++ +LL+ + L + ++K + Q Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682 Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398 + D + +++ D+ F + I+ G +++ + + EK+Q Sbjct: 683 ALMHTSNDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742 Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458 +T + ++L E + L K+ R +L TS K+ Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786 Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493 +L +V+P + + L I + ++ + +S + Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821 >gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] Length = 828 Score = 35.0 bits (79), Expect = 0.47 Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%) Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234 F IEK L E + ++KE +L ++KY+ I+ E + K+ + + +L + Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567 Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283 + K + E I+ ++ E LL N L D +++EL QL Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624 Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342 D+ +K+ K K++EN YI + ++ +LL+ + L + ++K + Q Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682 Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398 + D + +++ D+ F + I+ G +++ + + EK+Q Sbjct: 683 ALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742 Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458 +T + ++L E + L K+ R +L TS K+ Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786 Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493 +L +V+P + + L I + ++ + +S + Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821 >gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] Length = 828 Score = 35.0 bits (79), Expect = 0.47 Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%) Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234 F IEK L E + ++KE +L ++KY+ I+ E + K+ + + +L + Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567 Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283 + K + E I+ ++ E LL N L D +++EL QL Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624 Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342 D+ +K+ K K++EN YI + ++ +LL+ + L + ++K + Q Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682 Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398 + D + +++ D+ F + I+ G +++ + + EK+Q Sbjct: 683 ALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742 Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458 +T + ++L E + L K+ R +L TS K+ Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786 Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493 +L +V+P + + L I + ++ + +S + Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 35.0 bits (79), Expect = 0.47 Identities = 64/305 (20%), Positives = 126/305 (41%), Gaps = 35/305 (11%) Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131 + Q ++E E + LQ + + K TD +R ++L + + +L Q + Sbjct: 1346 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQD 1401 Query: 132 GETQIVADEAFCNAVRSYYEVFLKS--DRVARMVQSGGCSA------NDFREVFKKNIEK 183 E + A A C+++ D + + +S +A +F ++ + +K Sbjct: 1402 AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQK 1461 Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDL-----CKQPNRMALSAVSELILSKE 237 S E++ KE LS+ + K Y EE L K+ N+ +S+L E Sbjct: 1462 YEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENKNLQEEISDLT---E 1516 Query: 238 QLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFP 294 QL E + + ++K+ QL +L +A E+A +G R QL K Sbjct: 1517 QLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER 1576 Query: 295 KFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEI 354 K KD E +E+ + + ++ +L++ ++ ++ ++K+ GD NE+ Sbjct: 1577 KLAEKDEE---MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME------GDLNEM 1627 Query: 355 QLSKS 359 ++ S Sbjct: 1628 EIQLS 1632 >gi|5174457 kinetochore associated 2 [Homo sapiens] Length = 642 Score = 34.7 bits (78), Expect = 0.61 Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 9/187 (4%) Query: 157 DRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEED 216 D + +S A+ F E+ ++ +++ L +D E++ + A + I R E++ Sbjct: 227 DYTIKCYESFMSGADSFDEM-NAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQE 285 Query: 217 LCKQPNRM-ALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRR 275 K+PNR+ +L + + Q Y+ + + LE +L+ +E+ A++ Sbjct: 286 REKEPNRLESLRKLKASLQGDVQKYQAY-----MSNLESHSAILDQKLNGLNEEIARVEL 340 Query: 276 ELDGRLQLADKMAKERKFPKFIAKDMENMYIE--ELRSSVNLLMANLESLPVSKGGPEFK 333 E + Q ++ K+ D+E + E EL+ ++N L +LE+ E K Sbjct: 341 ECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELK 400 Query: 334 LQKLKRS 340 + K + Sbjct: 401 YARGKEA 407 >gi|33946313 ninein isoform 4 [Homo sapiens] Length = 2096 Score = 34.7 bits (78), Expect = 0.61 Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%) Query: 100 NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154 N K T+++R QQ+L K + L L E F + N + V Sbjct: 1087 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1146 Query: 155 K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208 + D R + S G S+ +EV + E V E++ S+ET SW K + Sbjct: 1147 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1204 Query: 209 AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258 I + +E L C + + + ++ + K++L +M ++I +++LLY Sbjct: 1205 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1262 Query: 259 --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308 N C ++ ++A + +EL + +L D++ K E F++ + ++ Sbjct: 1263 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1322 Query: 309 LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363 +N+L+ L+ K++KL+ S + + EN EI+ + + L Sbjct: 1323 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1372 Query: 364 SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 + TLE + V+ + V I C E +EG ++ +A W G T Sbjct: 1373 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1427 Query: 421 RPVVKVK-LFTESTGVLALEDK 441 RP V+ + + E+T +L +DK Sbjct: 1428 RPRVQNQVILEENTTLLGFQDK 1449 >gi|33946321 ninein isoform 5 [Homo sapiens] Length = 2090 Score = 34.7 bits (78), Expect = 0.61 Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%) Query: 100 NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154 N K T+++R QQ+L K + L L E F + N + V Sbjct: 1081 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1140 Query: 155 K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208 + D R + S G S+ +EV + E V E++ S+ET SW K + Sbjct: 1141 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1198 Query: 209 AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258 I + +E L C + + + ++ + K++L +M ++I +++LLY Sbjct: 1199 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1256 Query: 259 --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308 N C ++ ++A + +EL + +L D++ K E F++ + ++ Sbjct: 1257 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1316 Query: 309 LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363 +N+L+ L+ K++KL+ S + + EN EI+ + + L Sbjct: 1317 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1366 Query: 364 SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 + TLE + V+ + V I C E +EG ++ +A W G T Sbjct: 1367 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1421 Query: 421 RPVVKVK-LFTESTGVLALEDK 441 RP V+ + + E+T +L +DK Sbjct: 1422 RPRVQNQVILEENTTLLGFQDK 1443 >gi|148536871 ninein isoform 1 [Homo sapiens] Length = 2046 Score = 34.7 bits (78), Expect = 0.61 Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%) Query: 100 NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154 N K T+++R QQ+L K + L L E F + N + V Sbjct: 1081 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1140 Query: 155 K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208 + D R + S G S+ +EV + E V E++ S+ET SW K + Sbjct: 1141 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1198 Query: 209 AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258 I + +E L C + + + ++ + K++L +M ++I +++LLY Sbjct: 1199 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1256 Query: 259 --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308 N C ++ ++A + +EL + +L D++ K E F++ + ++ Sbjct: 1257 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1316 Query: 309 LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363 +N+L+ L+ K++KL+ S + + EN EI+ + + L Sbjct: 1317 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1366 Query: 364 SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420 + TLE + V+ + V I C E +EG ++ +A W G T Sbjct: 1367 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1421 Query: 421 RPVVKVK-LFTESTGVLALEDK 441 RP V+ + + E+T +L +DK Sbjct: 1422 RPRVQNQVILEENTTLLGFQDK 1443 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 48,139,823 Number of Sequences: 37866 Number of extensions: 2181105 Number of successful extensions: 9036 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 105 Number of HSP's that attempted gapping in prelim test: 8878 Number of HSP's gapped (non-prelim): 218 length of query: 1296 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1182 effective length of database: 13,930,794 effective search space: 16466198508 effective search space used: 16466198508 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.