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Search of human proteins with 148839284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148839284 Ca2+-dependent activator protein for secretion 2
isoform b [Homo sapiens]
(1255 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148839284 Ca2+-dependent activator protein for secretion 2 is... 2508 0.0
gi|148839294 Ca2+-dependent activator protein for secretion 2 is... 2453 0.0
gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo s... 1985 0.0
gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo s... 1964 0.0
gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo s... 1956 0.0
gi|122937247 unc-13 homolog A [Homo sapiens] 65 5e-10
gi|122937514 unc-13 homolog C [Homo sapiens] 57 1e-07
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 57 1e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 44 0.001
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.018
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.018
gi|50083279 centrosome protein 4 [Homo sapiens] 39 0.041
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 38 0.053
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 38 0.053
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 37 0.091
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 37 0.15
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 37 0.15
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 36 0.26
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 36 0.26
gi|4758968 cytohesin 3 [Homo sapiens] 36 0.26
gi|71061468 centromere protein E [Homo sapiens] 35 0.34
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 35 0.34
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 35 0.45
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 35 0.45
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] 35 0.45
gi|156104908 myosin heavy chain 6 [Homo sapiens] 35 0.45
gi|5174457 kinetochore associated 2 [Homo sapiens] 35 0.59
gi|33946313 ninein isoform 4 [Homo sapiens] 35 0.59
gi|33946321 ninein isoform 5 [Homo sapiens] 35 0.59
gi|148536871 ninein isoform 1 [Homo sapiens] 35 0.59
>gi|148839284 Ca2+-dependent activator protein for secretion 2 isoform
b [Homo sapiens]
Length = 1255
Score = 2508 bits (6500), Expect = 0.0
Identities = 1255/1255 (100%), Positives = 1255/1255 (100%)
Query: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS
Sbjct: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60
Query: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120
PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ
Sbjct: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120
Query: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180
LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN
Sbjct: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180
Query: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240
IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY
Sbjct: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240
Query: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300
EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD
Sbjct: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300
Query: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD
Sbjct: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
Query: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP
Sbjct: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
Query: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480
RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV
Sbjct: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480
Query: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540
RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG
Sbjct: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540
Query: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600
YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ
Sbjct: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600
Query: 601 TQKLNPKGGTLHADAQLYADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSY 660
TQKLNPKGGTLHADAQLYADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSY
Sbjct: 601 TQKLNPKGGTLHADAQLYADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSY 660
Query: 661 SCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCAS 720
SCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCAS
Sbjct: 661 SCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCAS 720
Query: 721 HVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLE 780
HVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLE
Sbjct: 721 HVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLE 780
Query: 781 RVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEILHL 840
RVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEILHL
Sbjct: 781 RVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEILHL 840
Query: 841 AELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQ 900
AELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQ
Sbjct: 841 AELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQ 900
Query: 901 LLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGS 960
LLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGS
Sbjct: 901 LLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGS 960
Query: 961 ATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQK 1020
ATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQK
Sbjct: 961 ATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQK 1020
Query: 1021 ASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKE 1080
ASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKE
Sbjct: 1021 ASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKE 1080
Query: 1081 IISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMF 1140
IISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMF
Sbjct: 1081 IISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMF 1140
Query: 1141 VRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKT 1200
VRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKT
Sbjct: 1141 VRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKT 1200
Query: 1201 YRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1255
YRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG
Sbjct: 1201 YRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1255
>gi|148839294 Ca2+-dependent activator protein for secretion 2 isoform
a [Homo sapiens]
Length = 1296
Score = 2453 bits (6358), Expect = 0.0
Identities = 1248/1301 (95%), Positives = 1248/1301 (95%), Gaps = 51/1301 (3%)
Query: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS
Sbjct: 1 MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPS 60
Query: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120
PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ
Sbjct: 61 PSVLSEGRDEPQRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQ 120
Query: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180
LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN
Sbjct: 121 LLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKN 180
Query: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240
IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY
Sbjct: 181 IEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLY 240
Query: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300
EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD
Sbjct: 241 EMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKD 300
Query: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD
Sbjct: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
Query: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP
Sbjct: 361 VVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
Query: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480
RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV
Sbjct: 421 RPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAV 480
Query: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540
RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG
Sbjct: 481 RMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEG 540
Query: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600
YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ
Sbjct: 541 YTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQ 600
Query: 601 TQKLNPKGGTLHADAQLY---ADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 657
TQKLNPKGGTLHADAQL ADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN
Sbjct: 601 TQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLN 660
Query: 658 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 717
DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF
Sbjct: 661 DSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAF 720
Query: 718 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 777
CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS
Sbjct: 721 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLS 780
Query: 778 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 837
LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI
Sbjct: 781 LLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEI 840
Query: 838 LHLAELCIEVLQQNEEHHA---EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 894
LHLAELCIEVLQQNEEHHA EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD
Sbjct: 841 LHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWD 900
Query: 895 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 954
SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ
Sbjct: 901 SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQ 960
Query: 955 PV----------------------------------------NNGSATSEDLFWKLDALQ 974
PV NGSATSEDLFWKLDALQ
Sbjct: 961 PVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQ 1020
Query: 975 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1034
MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC
Sbjct: 1021 MFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVC 1080
Query: 1035 TMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLE 1094
TMFNVLVDAKKQSTKLCALDGGQE QQYHSKIDDLIDNSVKEIISLLVSKFVSVLE
Sbjct: 1081 TMFNVLVDAKKQSTKLCALDGGQE-----QQYHSKIDDLIDNSVKEIISLLVSKFVSVLE 1135
Query: 1095 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE 1154
GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE
Sbjct: 1136 GVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNE 1195
Query: 1155 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL 1214
EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL
Sbjct: 1196 EMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL 1255
Query: 1215 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1255
NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG
Sbjct: 1256 NSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG 1296
>gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo
sapiens]
Length = 1314
Score = 1985 bits (5142), Expect = 0.0
Identities = 1000/1317 (75%), Positives = 1124/1317 (85%), Gaps = 69/1317 (5%)
Query: 1 MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51
MLDPSSSEEESDE +EEES ++VL +A S R P+ T EG + G GGG
Sbjct: 1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60
Query: 52 ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86
G R SPSPSV+SE ++E +R +E+ER+ RLQ
Sbjct: 61 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120
Query: 87 LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146
LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV
Sbjct: 121 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180
Query: 147 RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206
+SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK
Sbjct: 181 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240
Query: 207 YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266
+DAIYRGEED KQ RM SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN
Sbjct: 241 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300
Query: 267 DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326
DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS
Sbjct: 301 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360
Query: 327 KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386
KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV
Sbjct: 361 KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419
Query: 387 YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445
YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH P VKVKLFTESTGVLALEDKELGR
Sbjct: 420 YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479
Query: 446 VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505
VIL+PT NS K +E H+M V KN D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW
Sbjct: 480 VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539
Query: 506 KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565
KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG FFNAVKEG
Sbjct: 540 KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599
Query: 566 DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADA---QLYADR 621
DTVIFASDDEQDRILWVQAMYRATGQS+KPVP Q QKLN KGG + DA Q YADR
Sbjct: 600 DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659
Query: 622 FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 681
QKHGMDEFIS+NPC DHA LF ++QR TLDHRLNDSYSCLGWFSPGQVFVLDEYCAR
Sbjct: 660 AQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARN 719
Query: 682 GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 741
GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF
Sbjct: 720 GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 779
Query: 742 EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 801
EEIKERL LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R
Sbjct: 780 EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 839
Query: 802 KCLEKAALINYTRLTEYAKIEETMNQ------------------------ASPARKLEEI 837
KCLE+AAL+NY+RL+EYAKIE + +PA+KLE+
Sbjct: 840 KCLEQAALVNYSRLSEYAKIEGKKREMYEHPVFCLASQVMDLTIQNVGRLITPAKKLEDT 899
Query: 838 LHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFP 897
+ LAEL IEVLQQNEEHHAEAFAWW DL+ EHAE F +LF VDMD ALE QP D+WDSFP
Sbjct: 900 IRLAELVIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFP 959
Query: 898 LFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVN 957
LFQLLN+FLR D LCNGKFHKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PVN
Sbjct: 960 LFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVN 1019
Query: 958 NGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELK 1017
NGS TSEDLFWKLDALQ F+ DLHWPE+EF HLEQRLKLMASDM+E+CVKRTR AFE+K
Sbjct: 1020 NGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVK 1079
Query: 1018 LQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNS 1077
LQK S++TD R+P S+CTMFNV+VDAK QSTKLC+++ GQE QYHSKID+LI+ +
Sbjct: 1080 LQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQE-----HQYHSKIDELIEET 1134
Query: 1078 VKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTY 1137
VKE+I+LLV+KFV++LEGVL+KLSRYDEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y
Sbjct: 1135 VKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAY 1194
Query: 1138 IMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIV 1197
+ FVR +QD+LR+KVNEEMYIE+LFDQWY+SSM VIC WLTDR+DLQLHIYQLKTLI++V
Sbjct: 1195 VTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMV 1254
Query: 1198 KKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEE 1254
KKTYRDFRLQGVL+ TLNSKTY+T+ RLTVEEATASVSEGGGLQGI+MKDSDEE+E
Sbjct: 1255 KKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDE 1311
>gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo
sapiens]
Length = 1353
Score = 1964 bits (5088), Expect = 0.0
Identities = 1001/1356 (73%), Positives = 1125/1356 (82%), Gaps = 108/1356 (7%)
Query: 1 MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51
MLDPSSSEEESDE +EEES ++VL +A S R P+ T EG + G GGG
Sbjct: 1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60
Query: 52 ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86
G R SPSPSV+SE ++E +R +E+ER+ RLQ
Sbjct: 61 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120
Query: 87 LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146
LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV
Sbjct: 121 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180
Query: 147 RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206
+SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK
Sbjct: 181 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240
Query: 207 YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266
+DAIYRGEED KQ RM SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN
Sbjct: 241 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300
Query: 267 DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326
DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS
Sbjct: 301 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360
Query: 327 KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386
KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV
Sbjct: 361 KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419
Query: 387 YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445
YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH P VKVKLFTESTGVLALEDKELGR
Sbjct: 420 YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479
Query: 446 VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505
VIL+PT NS K +E H+M V KN D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW
Sbjct: 480 VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539
Query: 506 KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565
KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG FFNAVKEG
Sbjct: 540 KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599
Query: 566 DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADA---QLYADR 621
DTVIFASDDEQDRILWVQAMYRATGQS+KPVP Q QKLN KGG + DA Q YADR
Sbjct: 600 DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659
Query: 622 FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 681
QKHGMDEFIS+NPC DHA LF ++QR TLDHRLNDSYSCLGWFSPGQVFVLDEYCAR
Sbjct: 660 AQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARN 719
Query: 682 GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 741
GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF
Sbjct: 720 GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 779
Query: 742 EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 801
EEIKERL LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R
Sbjct: 780 EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 839
Query: 802 KCLEKAALINYTRLTEYAKIEETMNQA-------SPARKLEEILHLAELCIEVLQQNEEH 854
KCLE+AAL+NY+RL+EYAKIEE A +PA+KLE+ + LAEL IEVLQQNEEH
Sbjct: 840 KCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEH 899
Query: 855 HA-------EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLR 907
HA EAFAWW DL+ EHAE F +LF VDMD ALE QP D+WDSFPLFQLLN+FLR
Sbjct: 900 HAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLR 959
Query: 908 NDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPV----------- 956
D LCNGKFHKHLQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PV
Sbjct: 960 TDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVN 1019
Query: 957 --------------------------------------NNGSATSEDLFWKLDALQMFVF 978
+NGS TSEDLFWKLDALQ F+
Sbjct: 1020 LPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIR 1079
Query: 979 DLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFN 1038
DLHWPE+EF HLEQRLKLMASDM+E+CVKRTR AFE+KLQK S++TD R+P S+CTMFN
Sbjct: 1080 DLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFN 1139
Query: 1039 VLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLS 1098
V+VDAK QSTKLC+++ GQE QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+
Sbjct: 1140 VMVDAKAQSTKLCSMEMGQE-----HQYHSKIDELIEETVKEMITLLVAKFVTILEGVLA 1194
Query: 1099 KLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYI 1158
KLSRYDEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYI
Sbjct: 1195 KLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYI 1254
Query: 1159 EKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKT 1218
E+LFDQWY+SSM VIC WLTDR+DLQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKT
Sbjct: 1255 ERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKT 1314
Query: 1219 YDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEEE 1254
Y+T+ RLTVEEATASVSEGGGLQGI+MKDSDEE+E
Sbjct: 1315 YETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDE 1350
>gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo
sapiens]
Length = 1274
Score = 1956 bits (5066), Expect = 0.0
Identities = 986/1294 (76%), Positives = 1110/1294 (85%), Gaps = 63/1294 (4%)
Query: 1 MLDPSSSEEESDEGLEEES-RDVLVAAGSSQRAPPAPTREGRRDAPGRAGGG-------- 51
MLDPSSSEEESDE +EEES ++VL +A S R P+ T EG + G GGG
Sbjct: 1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 60
Query: 52 ------------------------GAARSVSPSPSVLSEG-RDEPQRQLDDEQERRIRLQ 86
G R SPSPSV+SE ++E +R +E+ER+ RLQ
Sbjct: 61 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 120
Query: 87 LYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAV 146
LYVFV+RCIAYPFNAKQPTDMARRQQK++KQQLQ +K+RFQAFLNGETQI+ADEAF NAV
Sbjct: 121 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 180
Query: 147 RSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAK 206
+SYYEVFLKSDRVARMVQSGGCSAND REVFKK+IEKRVRSLPEIDGLSKETVLSSW+AK
Sbjct: 181 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 240
Query: 207 YDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNA 266
+DAIYRGEED KQ RM SA SELILSKEQLYEMFQ ILGIKK EHQLLYNACQLDN
Sbjct: 241 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 300
Query: 267 DEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS 326
DEQAAQIRRELDGRLQ+AD++A+ERKFPKF++K+MENMYIEEL+SSVNLLMANLES+PVS
Sbjct: 301 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 360
Query: 327 KGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 386
KGG EFKLQKLKRS N++ +D+G+E+E QLSKSDVVLSF+LE+VIMEVQGLKS+APNRIV
Sbjct: 361 KGG-EFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIV 419
Query: 387 YCTMEVE-GEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGR 445
YCTMEVE GEKLQTDQAEAS+P WGTQGDF+TTH P VKVKLFTESTGVLALEDKELGR
Sbjct: 420 YCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGR 479
Query: 446 VILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRW 505
VIL+PT NS K +E H+M V KN D DLKIKLAVRMDKP +MKHSGYL+A+G+ VWKRW
Sbjct: 480 VILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRW 539
Query: 506 KKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEG 565
KKR+FVLVQVSQYTFAMCSYREKK+EPQEL+QL+GYTVDYTDP PGL+GG FFNAVKEG
Sbjct: 540 KKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEG 599
Query: 566 DTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTL-HADA---QLYADR 621
DTVIFASDDEQDRILWVQAMYRATGQS+KPVP Q QKLN KGG + DA Q YADR
Sbjct: 600 DTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADR 659
Query: 622 FQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARY 681
QKHGMDEFIS+NPC DHA LF +GWFSPGQVFVLDEYCAR
Sbjct: 660 AQKHGMDEFISSNPCNFDHASLFE-----------------MGWFSPGQVFVLDEYCARN 702
Query: 682 GVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERF 741
GVRGCHRHLCYL +L+E +ENGA+IDPTLLHYSFAFCASHVHGNRPDGIGTV+VEEKERF
Sbjct: 703 GVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERF 762
Query: 742 EEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVR 801
EEIKERL LLENQI+HFRYCFPFGRPEGALKATLSLLERVLMKDI TP+P EEVK V+R
Sbjct: 763 EEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIR 822
Query: 802 KCLEKAALINYTRLTEYAKIEETMNQ-ASPARKLEEILHLAELCIEVLQQNEEHHAEAFA 860
KCLE+AAL+NY+RL+EYAKIEE + + +PA+KLE+ + LAEL IEVLQQNEEHHAEAFA
Sbjct: 823 KCLEQAALVNYSRLSEYAKIEENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEAFA 882
Query: 861 WWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKH 920
WW DL+ EHAE F +LF VDMD ALE QP D+WDSFPLFQLLN+FLR D LCNGKFHKH
Sbjct: 883 WWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKH 942
Query: 921 LQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDL 980
LQ++F PLVVRYVDLMESSIAQSIHRGFE+E+W+PVNNGS TSEDLFWKLDALQ F+ DL
Sbjct: 943 LQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVNNGSGTSEDLFWKLDALQTFIRDL 1002
Query: 981 HWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVL 1040
HWPE+EF HLEQRLKLMASDM+E+CVKRTR AFE+KLQK S++TD R+P S+CTMFNV+
Sbjct: 1003 HWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVM 1062
Query: 1041 VDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKL 1100
VDAK QSTKLC+++ GQE QYHSKID+LI+ +VKE+I+LLV+KFV++LEGVL+KL
Sbjct: 1063 VDAKAQSTKLCSMEMGQE-----HQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL 1117
Query: 1101 SRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEK 1160
SRYDEGT FSS LSFTVKAA+KYVDVPKPGMD+AD Y+ FVR +QD+LR+KVNEEMYIE+
Sbjct: 1118 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER 1177
Query: 1161 LFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYD 1220
LFDQWY+SSM VIC WLTDR+DLQLHIYQLKTLI++VKKTYRDFRLQGVL+ TLNSKTY+
Sbjct: 1178 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYE 1237
Query: 1221 TVHRRLTVEEATASVSEGGGLQGITMKDSDEEEE 1254
T+ RLTVEEATASVSEGGGLQGI+MKDSDEE+E
Sbjct: 1238 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDE 1271
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 64.7 bits (156), Expect = 5e-10
Identities = 109/528 (20%), Positives = 216/528 (40%), Gaps = 52/528 (9%)
Query: 673 VLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLLHYSFAFCASHVHGNRPDGI 730
++DE+ RYGV ++ + + A L V + TLL A+ A
Sbjct: 949 IVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 1008
Query: 731 GTVSVEE--KERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKATLSLLE-----R 781
+ KERF ++ ++L + L +S +R FP PE LK+T+ LL R
Sbjct: 1009 DRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFR 1068
Query: 782 VLMKDIATPIPAEE-VKKVVRKCLEKA---------ALINYTRLTEYAKIEETM--NQAS 829
+ ++++ +P A + VK V+ CL L + T+ AK E + Q
Sbjct: 1069 MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGP 1128
Query: 830 PARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLL---AEHAEKFWALFTVDMDTALE 886
+ L+ L L + ++++++ + +P L AE W LF DM A+E
Sbjct: 1129 SIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAME 1188
Query: 887 AQPQDSWDSFPLFQLLN---NFLRNDTLLCNGKFHKHLQEI---FVPLVVRYVDLMESSI 940
+ + L+ +L N+ + F + E F P V++++D E
Sbjct: 1189 EHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVS 1248
Query: 941 AQSIHRGFEQET---WQPVNNG---SATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQR 994
+H E++ +Q + S + D+F +L+ + L P+ + H +R
Sbjct: 1249 RDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRR 1308
Query: 995 LKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALD 1054
S++L F K + ++P C + N + Q K+
Sbjct: 1309 FAKTISNVLLQYADIISKDFASYCSKEKE----KVP---CILMNNTQQLRVQLEKMFEAM 1361
Query: 1055 GGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLS---RYDEGTFFSS 1111
GG+E ++ ++ ++N + E+ + + F +E + ++ +GT +
Sbjct: 1362 GGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGT--GN 1419
Query: 1112 ILSFTVKAAAKYVD-VPKPGMDLADTYI-MFVRQNQDILREKVNEEMY 1157
+ + + A+ D V +P MDL D+ + +F + + + ++V +E++
Sbjct: 1420 VPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELW 1467
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 56.6 bits (135), Expect = 1e-07
Identities = 99/480 (20%), Positives = 192/480 (40%), Gaps = 57/480 (11%)
Query: 665 WFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLL-----HYSFAF 717
+F ++DE+ RYG+ ++ + + + L V + TLL Y+
Sbjct: 1397 FFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTT 1456
Query: 718 CASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKAT 775
++++ + D + +E+F ++ ++L + L +S +R FP E LK+T
Sbjct: 1457 VSTNIQVSASDRFAATNFG-REKFIKLLDQLHNSLRIDLSKYRENFPASNTERLQDLKST 1515
Query: 776 LSLLE-----RVLMKDIATPIPAEEV-KKVVRKCLE---KAALIN----YTRLTEYAKIE 822
+ LL R+ + ++ +P A V K VR CL+ K N Y++LT+ +K +
Sbjct: 1516 VDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDSTYKYIFDNCHELYSQLTDPSKKQ 1575
Query: 823 ETM--NQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAE---HAEKFWALF 877
+ +Q + L+ L L + ++ +++ + +P L AE W LF
Sbjct: 1576 DIPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQELNMGKISAEIMWTLF 1635
Query: 878 TVDMDTALEAQPQD----SWD----SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLV 929
+DM ALE S D F + N ++R + L F P V
Sbjct: 1636 ALDMKYALEEHENQRLCKSTDYMNLHFKVKWFYNEYVRELPAFKDAVPEYSLW--FEPFV 1693
Query: 930 VRYVDLMESSIAQSIH--------RGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLH 981
++++D E + +H GF+Q + + + S D+F +L+ + L
Sbjct: 1694 MQWLDENEDVSMEFLHGALGRDKKDGFQQTSEHALFSCSVV--DVFAQLNQSFEIIKKLE 1751
Query: 982 WPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLV 1041
P E HL +R + +L + F K + +P C + N +
Sbjct: 1752 CPNPEALSHLMRRFAKTINKVLLQYAAIVSSDFSSHCDKEN------VP---CILMNNIQ 1802
Query: 1042 DAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLS 1101
+ Q K+ GG+E S+ ++ + + E+ F ++E + ++S
Sbjct: 1803 QLRVQLEKMFESMGGKELDSEASTILKELQVKLSGVLDELSVTYGESFQVIIEECIKQMS 1862
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 56.6 bits (135), Expect = 1e-07
Identities = 94/425 (22%), Positives = 176/425 (41%), Gaps = 53/425 (12%)
Query: 673 VLDEYCARYGVRGCHRHLCYLAELMEHSENGAV--IDPTLLHYSFAFCASHVHGNRPDGI 730
++DE+ RYG+ ++ + + A L V + TLL A+ A
Sbjct: 785 IVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 844
Query: 731 GTVSVEE--KERFEEIKERLSSLLENQISHFRYCFPFGRPEGA--LKATLSLLE-----R 781
+ KERF ++ ++L + L +S +R FP G PE LK+T+ LL R
Sbjct: 845 DRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFR 904
Query: 782 VLMKDIATPIPAEE-VKKVVRKCLEKA--ALIN-----YTRLTEYAKIEETMNQASPARK 833
+ ++++ +P A + VK V+ CL + N Y+R + + Q R
Sbjct: 905 MKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRN 964
Query: 834 LEEILHLAELCIEVLQQNEEHHAEAFAWWPDLL---AEHAEKFWALFTVDMDTALEAQPQ 890
L+ L L + ++++++ + +P L AE W LF DM ALE +
Sbjct: 965 LDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEK 1024
Query: 891 D----SWD----SFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVD-------- 934
D S D F + L N ++R D + G+ ++ F V++++D
Sbjct: 1025 DHLCKSADYMNLHFKVKWLHNEYVR-DLPVLQGQVPEY-PAWFEQFVLQWLDENEDVSLE 1082
Query: 935 LMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQE-FAHHLEQ 993
+ ++ + GF+Q + + + S D+F +L+ + L P+ AH++ +
Sbjct: 1083 FLRGALERDKKDGFQQTSEHALFSCSVV--DVFTQLNQSFEIIRKLECPDPSILAHYMRR 1140
Query: 994 RLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCAL 1053
K + +++ A L + T ++P C + N + + Q K+
Sbjct: 1141 FAKTIGKVLMQ-------YADILSKDFPAYCTKEKLP---CILMNNVQQLRVQLEKMFEA 1190
Query: 1054 DGGQE 1058
GG+E
Sbjct: 1191 MGGKE 1195
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 43.5 bits (101), Expect = 0.001
Identities = 58/263 (22%), Positives = 113/263 (42%), Gaps = 19/263 (7%)
Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
+ Q ++EQE + LQ + + K TD +R ++L + + +L + +A
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA--- 1403
Query: 132 GETQIVADEAFCNAVRSYYEVFLKS--DRVARMVQSGG-CSAND-----FREVFKKNIEK 183
E + A A C ++ + D + + +S C+A D F +V + +K
Sbjct: 1404 -EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQK 1462
Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242
+ E++ KE+ LS+ + K +Y D + R + E+ EQ+ E
Sbjct: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEG 1522
Query: 243 FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299
+QI ++K++ Q+ C++ A E+A +G R+QL K K K
Sbjct: 1523 GKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1582
Query: 300 DMENMYIEELRSSVNLLMANLES 322
D E I++L+ + ++ ++S
Sbjct: 1583 DEE---IDQLKRNHTRVVETMQS 1602
Score = 32.7 bits (73), Expect = 2.2
Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 20/131 (15%)
Query: 225 ALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLA 284
A SA EL +E ++ ++ L L+H+ + A + +AD A++ ++D ++
Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSM-AELGEQIDNLQRVK 1217
Query: 285 DKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSA 344
K+ KE+ EL+ + L +N E++ +KG L+K+ RS
Sbjct: 1218 QKLEKEK---------------SELKMETDDLSSNAEAISKAKG----NLEKMCRSLEDQ 1258
Query: 345 FLDIGDENEIQ 355
++ + E Q
Sbjct: 1259 VSELKTKEEEQ 1269
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 39.7 bits (91), Expect = 0.018
Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 25/297 (8%)
Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
+ Q ++EQE + LQ + + K TD +R ++L + + +L +R QA
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQA--- 1405
Query: 132 GETQIVADEAFCNAVRS--------YYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEK 183
E + A A C ++ ++ L +R + +F ++ + +K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242
+ E++ KE L + + K Y D + R + E+ EQ+ E
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 243 FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299
++I ++K++ Q+ C+L A E+A +G R+QL K K K
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585
Query: 300 DMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356
D E I++L+ + ++ +++S ++ +LK+ GD NE+++
Sbjct: 1586 DEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1633
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 39.7 bits (91), Expect = 0.018
Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 25/297 (8%)
Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
+ Q ++EQE + LQ + + K TD +R ++L + + +L +R QA
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQA--- 1405
Query: 132 GETQIVADEAFCNAVRS--------YYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEK 183
E + A A C ++ ++ L +R + +F ++ + +K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEM 242
+ E++ KE L + + K Y D + R + E+ EQ+ E
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 243 FQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIAK 299
++I ++K++ Q+ C+L A E+A +G R+QL K K K
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585
Query: 300 DMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356
D E I++L+ + ++ +++S ++ +LK+ GD NE+++
Sbjct: 1586 DEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1633
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 38.5 bits (88), Expect = 0.041
Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 16/167 (9%)
Query: 172 DFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSE 231
DF + K++EKR+R L E +KETV S + + E LC++ + A +
Sbjct: 278 DFLQQANKDLEKRIRELME----TKETVTSEVV----NLSNKNEKLCQELTEIDQLA-QQ 328
Query: 232 LILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKER 291
L KE++ E + LG K E + ++ + +E A+++ EL+ L K KER
Sbjct: 329 LERHKEEVLETADKELGEAKKE--IKRKLSEMQDLEETMAKLQLELN----LCQK-EKER 381
Query: 292 KFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLK 338
+ + K + +L L +ES V++ ++++++
Sbjct: 382 LSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERMR 428
>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
gamma [Homo sapiens]
Length = 850
Score = 38.1 bits (87), Expect = 0.053
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
SR +LV + + +PPAP+ RR D G G + VSP +LS GR + +
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648
Query: 74 ---QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFL 130
+ EQ+RR ++L + + +A+ +++ + L+ ++ +A L
Sbjct: 649 RITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGL 708
Query: 131 NGETQIVADE 140
E Q + DE
Sbjct: 709 QEEAQQLRDE 718
>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
Length = 731
Score = 38.1 bits (87), Expect = 0.053
Identities = 68/290 (23%), Positives = 122/290 (42%), Gaps = 44/290 (15%)
Query: 109 RRQQKLNKQQLQLLKERFQAFLNG---ETQIVADEAFCNAVRSYYEVFLKSDRVARMV-- 163
+R+Q+ KQ ++ F A LN E Q +A EA A R Y + + D + + V
Sbjct: 362 KREQESYKQ----MQSEFAARLNKVEMERQNLA-EAITLAERKYSDEKKRVDELQQQVKL 416
Query: 164 -----QSGGCSANDFREVFKKNI---EKRVRSLPE---IDGLSKETVLSSWIA--KYDAI 210
+S D+++ + + EK + SL E +GL T S + +++
Sbjct: 417 YKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTASSMELEELRHEKE 476
Query: 211 YRGEE---------DLCKQPNRMALSAVSELILSKEQLYEMFQQILGIK----KLEHQLL 257
+ EE L + M V+E ++EQL ++ QI G K +LE +L
Sbjct: 477 MQREEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELE 536
Query: 258 YNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLM 317
+ +E + + L R++ D+ ++ + + K + N EL + ++ L
Sbjct: 537 RLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLR-NQLTNKTLSNSSQSELENRLHQLT 595
Query: 318 ANL-------ESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSD 360
L ESL K F+L++L++ NSA + + I +S D
Sbjct: 596 ETLIQKQTMLESLSTEKNSLVFQLERLEQQMNSASGSSSNGSSINMSGID 645
>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
alpha [Homo sapiens]
Length = 852
Score = 37.4 bits (85), Expect = 0.091
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
SR +LV + + +PPAP+ RR D G G + VSP +LS GR + +
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648
Query: 74 -----QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQA 128
+ EQ+RR ++L + + +A+ +++ + L+ ++ +A
Sbjct: 649 NRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERA 708
Query: 129 FLNGETQIVADE 140
L E Q + DE
Sbjct: 709 GLQEEAQQLRDE 720
>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
delta [Homo sapiens]
Length = 831
Score = 36.6 bits (83), Expect = 0.15
Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 10/121 (8%)
Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
SR +LV + + +PPAP+ RR D G G + VSP +LS GR + +
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648
Query: 74 ---QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFL 130
+ EQ+RR ++L + + +A QP+ R + QQL+ E A +
Sbjct: 649 RITHISAEQKRRFNIKLGFDTLHGLVSTLSA-QPSLKERAGLQEEAQQLRDEIEELNAAI 707
Query: 131 N 131
N
Sbjct: 708 N 708
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 36.6 bits (83), Expect = 0.15
Identities = 61/298 (20%), Positives = 126/298 (42%), Gaps = 27/298 (9%)
Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
+ Q ++EQE + LQ + + K TD +R ++L + + +L Q +
Sbjct: 1348 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQD 1403
Query: 132 GETQIVADEAFCNAVRSYYEVFLKSDRVARMVQ----SGGCSAND-----FREVFKKNIE 182
E + A A C ++ + L+++ M+ + C+A D F ++ + +
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQR-LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462
Query: 183 KRVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYE 241
K + E++ KE+ LS+ + K Y D + R + E+ EQ+ E
Sbjct: 1463 KCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1522
Query: 242 MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFPKFIA 298
++I ++K++ Q+ +L A E+A +G R+QL K K
Sbjct: 1523 GGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1582
Query: 299 KDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQL 356
KD E I++++ + ++ +++S ++ +LK+ GD NE+++
Sbjct: 1583 KDEE---IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME------GDLNEMEI 1631
>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
beta [Homo sapiens]
Length = 833
Score = 35.8 bits (81), Expect = 0.26
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 12/123 (9%)
Query: 19 SRDVLVAAGSSQRAPPAPTREGRR---DAPGRAGGGGAARSVSPSPSVLSEGRDEPQR-- 73
SR +LV + + +PPAP+ RR D G G + VSP +LS GR + +
Sbjct: 590 SRPLLVPK-AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648
Query: 74 -----QLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQA 128
+ EQ+RR ++L + + +A QP+ R + QQL+ E A
Sbjct: 649 NRRITHISAEQKRRFNIKLGFDTLHGLVSTLSA-QPSLKERAGLQEEAQQLRDEIEELNA 707
Query: 129 FLN 131
+N
Sbjct: 708 AIN 710
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 35.8 bits (81), Expect = 0.26
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 477 KLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELM 536
K+ +D P+ + GYL+ +K W +R+F +Q SQ + +KK + +
Sbjct: 258 KVEFDVDAPSGVVMEGYLFKRASNAFKTWNRRWF-SIQNSQLVY------QKKLKDALTV 310
Query: 537 QLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPV 596
++ + P ++ F + + + +D E+ R WVQA+ + +Y+
Sbjct: 311 VVDDLRLCSVKPCEDIERR-FCFEVLSPTKSCMLQADSEKLRQAWVQAVQASIASAYRES 369
Query: 597 P 597
P
Sbjct: 370 P 370
>gi|4758968 cytohesin 3 [Homo sapiens]
Length = 399
Score = 35.8 bits (81), Expect = 0.26
Identities = 66/320 (20%), Positives = 132/320 (41%), Gaps = 35/320 (10%)
Query: 244 QQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMEN 303
+++L I++ + +L+ + ++ + A++ E+D + + +R + + N
Sbjct: 22 EELLDIRRRKKELIDD---IERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFN 78
Query: 304 MYIEELRSSVNLLMAN--LESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDV 361
M + + + L+ N L+S P +K + L ++ +L DE I++ ++ V
Sbjct: 79 M---DPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFV 135
Query: 362 VLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTD---QAEASRPQWGTQGDFTTT 418
L E L V R + + GE + D +A ASR G F +T
Sbjct: 136 ELH--------EFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQST 187
Query: 419 HPRPVVKVKLFTESTGVLA--LEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKI 476
V+ + +T + + DK + ++ +L ++ +N +S
Sbjct: 188 DTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELL-RNLYESIKNE 246
Query: 477 KLAVRMDKPAHMKHS-------GYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKK 529
+ D + H+ G+L LG +V K WK+R+F+L Y F Y K
Sbjct: 247 PFKIPEDDGNDLTHTFFNPDREGWLLKLGGRV-KTWKRRWFILTDNCLYYF---EYTTDK 302
Query: 530 SEPQELMQLEGYTV-DYTDP 548
EP+ ++ LE ++ + DP
Sbjct: 303 -EPRGIIPLENLSIREVEDP 321
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 35.4 bits (80), Expect = 0.34
Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 11/162 (6%)
Query: 172 DFREVFKKNIEKRVRSLPEIDGLSKETV---LSSWIAKYDAIYRGEEDLCKQPNRMALSA 228
DF + +K +E+ R EI LSKE S K + Y+ +E ++ R
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE--LQEKTREVQER 885
Query: 229 VSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMA 288
++E+ KEQL E L + E L+ +L E+ + +E D QL + +
Sbjct: 886 LNEMEQLKEQL-ENRDSTLQTVEREKTLITE--KLQQTLEEVKTLTQEKDDLKQLQESLQ 942
Query: 289 KERKFPKFIAKDMENMYI---EELRSSVNLLMANLESLPVSK 327
ER K D NM I E+LR+++ L + E++ K
Sbjct: 943 IERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 984
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 35.4 bits (80), Expect = 0.34
Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 8/126 (6%)
Query: 219 KQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELD 278
+Q R A EL+ + E+L + Q G+ + +L + QL E+AAQ RRE +
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1801
Query: 279 GRLQL----ADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVS--KGGPEF 332
+ + A MA+E K + + +E M + L +V L A LE + +GG +
Sbjct: 1802 EKAKKAITDAAMMAEELKKEQDTSAHLERMK-KTLEQTVRELQARLEEAEQAALRGGKK- 1859
Query: 333 KLQKLK 338
++QKL+
Sbjct: 1860 QVQKLE 1865
>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.45
Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%)
Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234
F IEK L E + ++KE +L ++KY+ I+ E + K+ + + +L +
Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567
Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283
+ K + E I+ ++ E LL N L D +++EL QL
Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624
Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342
D+ +K+ K K++EN YI + ++ +LL+ + L + ++K + Q
Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682
Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398
+ D + +++ D+ F + I+ G +++ + + EK+Q
Sbjct: 683 ALMHTSNDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742
Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458
+T + ++L E + L K+ R +L TS K+
Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786
Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493
+L +V+P + + L I + ++ + +S +
Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821
>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.45
Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%)
Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234
F IEK L E + ++KE +L ++KY+ I+ E + K+ + + +L +
Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567
Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283
+ K + E I+ ++ E LL N L D +++EL QL
Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624
Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342
D+ +K+ K K++EN YI + ++ +LL+ + L + ++K + Q
Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682
Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398
+ D + +++ D+ F + I+ G +++ + + EK+Q
Sbjct: 683 ALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742
Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458
+T + ++L E + L K+ R +L TS K+
Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786
Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493
+L +V+P + + L I + ++ + +S +
Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821
>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.45
Identities = 65/335 (19%), Positives = 135/335 (40%), Gaps = 39/335 (11%)
Query: 177 FKKNIEKRVRSLPEIDG--LSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELIL 234
F IEK L E + ++KE +L ++KY+ I+ E + K+ + + +L +
Sbjct: 508 FVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQV 567
Query: 235 S------KEQLYEMFQQILGIKKLEHQLLYNACQLDNAD-----EQAAQIRRELDGRLQL 283
+ K + E I+ ++ E LL N L D +++EL QL
Sbjct: 568 AEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQ---QL 624
Query: 284 ADKMAKERKFPKFIAKDMEN-MYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQN 342
D+ +K+ K K++EN YI + ++ +LL+ + L + ++K + Q
Sbjct: 625 RDQESKKNKDHFETLKNLENGFYINDQKA--DLLLLENKKLKEYILYLKNNIEKYREGQE 682
Query: 343 SAFLDIGDENEIQLSK----SDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQ 398
+ D + +++ D+ F + I+ G +++ + + EK+Q
Sbjct: 683 ALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQ 742
Query: 399 TDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSA 458
+T + ++L E + L K+ R +L TS K+
Sbjct: 743 ---------------HVSTWLRGSLEGLRLLVEQESPMDLLSKQQLRALLV-TSKEEKTC 786
Query: 459 ELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGY 493
+L +V+P + + L I + ++ + +S +
Sbjct: 787 QLSDLVIPNYATNIQLNIDTYLGLNTLVVLSNSAF 821
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 35.0 bits (79), Expect = 0.45
Identities = 64/305 (20%), Positives = 126/305 (41%), Gaps = 35/305 (11%)
Query: 72 QRQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLN 131
+ Q ++E E + LQ + + K TD +R ++L + + +L Q +
Sbjct: 1346 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQD 1401
Query: 132 GETQIVADEAFCNAVRSYYEVFLKS--DRVARMVQSGGCSA------NDFREVFKKNIEK 183
E + A A C+++ D + + +S +A +F ++ + +K
Sbjct: 1402 AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQK 1461
Query: 184 RVRSLPEIDGLSKET-VLSSWIAKYDAIYRGEEDL-----CKQPNRMALSAVSELILSKE 237
S E++ KE LS+ + K Y EE L K+ N+ +S+L E
Sbjct: 1462 YEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENKNLQEEISDLT---E 1516
Query: 238 QLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDG---RLQLADKMAKERKFP 294
QL E + + ++K+ QL +L +A E+A +G R QL K
Sbjct: 1517 QLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER 1576
Query: 295 KFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEI 354
K KD E +E+ + + ++ +L++ ++ ++ ++K+ GD NE+
Sbjct: 1577 KLAEKDEE---MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME------GDLNEM 1627
Query: 355 QLSKS 359
++ S
Sbjct: 1628 EIQLS 1632
>gi|5174457 kinetochore associated 2 [Homo sapiens]
Length = 642
Score = 34.7 bits (78), Expect = 0.59
Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 9/187 (4%)
Query: 157 DRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEED 216
D + +S A+ F E+ ++ +++ L +D E++ + A + I R E++
Sbjct: 227 DYTIKCYESFMSGADSFDEM-NAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQE 285
Query: 217 LCKQPNRM-ALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRR 275
K+PNR+ +L + + Q Y+ + + LE +L+ +E+ A++
Sbjct: 286 REKEPNRLESLRKLKASLQGDVQKYQAY-----MSNLESHSAILDQKLNGLNEEIARVEL 340
Query: 276 ELDGRLQLADKMAKERKFPKFIAKDMENMYIE--ELRSSVNLLMANLESLPVSKGGPEFK 333
E + Q ++ K+ D+E + E EL+ ++N L +LE+ E K
Sbjct: 341 ECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELK 400
Query: 334 LQKLKRS 340
+ K +
Sbjct: 401 YARGKEA 407
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 34.7 bits (78), Expect = 0.59
Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%)
Query: 100 NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154
N K T+++R QQ+L K + L L E F + N + V
Sbjct: 1087 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1146
Query: 155 K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208
+ D R + S G S+ +EV + E V E++ S+ET SW K +
Sbjct: 1147 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1204
Query: 209 AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258
I + +E L C + + + ++ + K++L +M ++I +++LLY
Sbjct: 1205 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1262
Query: 259 --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308
N C ++ ++A + +EL + +L D++ K E F++ + ++
Sbjct: 1263 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1322
Query: 309 LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363
+N+L+ L+ K++KL+ S + + EN EI+ + + L
Sbjct: 1323 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1372
Query: 364 SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
+ TLE + V+ + V I C E +EG ++ +A W G T
Sbjct: 1373 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1427
Query: 421 RPVVKVK-LFTESTGVLALEDK 441
RP V+ + + E+T +L +DK
Sbjct: 1428 RPRVQNQVILEENTTLLGFQDK 1449
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 34.7 bits (78), Expect = 0.59
Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%)
Query: 100 NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154
N K T+++R QQ+L K + L L E F + N + V
Sbjct: 1081 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1140
Query: 155 K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208
+ D R + S G S+ +EV + E V E++ S+ET SW K +
Sbjct: 1141 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1198
Query: 209 AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258
I + +E L C + + + ++ + K++L +M ++I +++LLY
Sbjct: 1199 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1256
Query: 259 --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308
N C ++ ++A + +EL + +L D++ K E F++ + ++
Sbjct: 1257 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1316
Query: 309 LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363
+N+L+ L+ K++KL+ S + + EN EI+ + + L
Sbjct: 1317 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1366
Query: 364 SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
+ TLE + V+ + V I C E +EG ++ +A W G T
Sbjct: 1367 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1421
Query: 421 RPVVKVK-LFTESTGVLALEDK 441
RP V+ + + E+T +L +DK
Sbjct: 1422 RPRVQNQVILEENTTLLGFQDK 1443
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 34.7 bits (78), Expect = 0.59
Identities = 85/382 (22%), Positives = 158/382 (41%), Gaps = 59/382 (15%)
Query: 100 NAKQPTDMARRQQKLNKQQLQL-----LKERFQAFLNGETQIVADEAFCNAVRSYYEVFL 154
N K T+++R QQ+L K + L L E F + N + V
Sbjct: 1081 NVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTR 1140
Query: 155 K------SDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYD 208
+ D R + S G S+ +EV + E V E++ S+ET SW K +
Sbjct: 1141 RHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELEN-SEETRTESWELK-N 1198
Query: 209 AIYRGEEDL------CKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLY---- 258
I + +E L C + + + ++ + K++L +M ++I +++LLY
Sbjct: 1199 QISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKL-KMLERIPEASP-KYKLLYEDVS 1256
Query: 259 --NAC------QLDNADEQAAQIRRELDGRL-QLADKMAK-ERKFPKFIAKDMENMYIEE 308
N C ++ ++A + +EL + +L D++ K E F++ + ++
Sbjct: 1257 RENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKI 1316
Query: 309 LRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQ----NSAFLDIGDEN-EIQLSKSDVVL 363
+N+L+ L+ K++KL+ S + + EN EI+ + + L
Sbjct: 1317 ENEELNVLVLRLQG----------KIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQL 1366
Query: 364 SFTLEIVIMEVQGLKSVAPNRIVYCTME---VEGEKLQTDQAEASRPQWGTQGDFTTTHP 420
+ TLE + V+ + V I C E +EG ++ +A W G T
Sbjct: 1367 NQTLEECVPRVRSVHHV----IEECKQENQYLEGNTQLLEKVKAHEIAW-LHGTIQTHQE 1421
Query: 421 RPVVKVK-LFTESTGVLALEDK 441
RP V+ + + E+T +L +DK
Sbjct: 1422 RPRVQNQVILEENTTLLGFQDK 1443
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,339,970
Number of Sequences: 37866
Number of extensions: 2080601
Number of successful extensions: 8665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 8511
Number of HSP's gapped (non-prelim): 221
length of query: 1255
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1141
effective length of database: 13,930,794
effective search space: 15895035954
effective search space used: 15895035954
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.