Search of human proteins with 148806923

Search of human proteins with 148806923

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148806923 testis serine protease 5 [Homo sapiens]
         (228 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148806923 testis serine protease 5 [Homo sapiens]                  487   e-138
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      151   5e-37
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  145   2e-35
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            145   4e-35
gi|4506153 prostasin preproprotein [Homo sapiens]                     142   3e-34
gi|5803197 testisin isoform 1 [Homo sapiens]                          134   8e-32
gi|13994276 marapsin [Homo sapiens]                                   133   1e-31
gi|148806900 epidermis-specific serine protease-like protein [Ho...   133   1e-31
gi|21614531 testisin isoform 2 [Homo sapiens]                         133   1e-31
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         131   5e-31
gi|7019563 testes-specific protease 50 [Homo sapiens]                 130   7e-31
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         125   4e-29
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          123   1e-28
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   122   3e-28
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   122   3e-28
gi|34098976 marapsin 2 [Homo sapiens]                                 122   3e-28
gi|118498341 chymotrypsin B1 [Homo sapiens]                           119   3e-27
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]               118   4e-27
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             117   6e-27
gi|33186882 testis serine protease 2 [Homo sapiens]                   115   2e-26
gi|4505881 plasminogen [Homo sapiens]                                 114   7e-26
gi|118498350 chymotrypsin B2 [Homo sapiens]                           114   7e-26
gi|4503137 chymotrypsin-like [Homo sapiens]                           114   9e-26
gi|4503627 coagulation factor XI precursor [Homo sapiens]             113   1e-25
gi|58218970 protease, serine, 36 [Homo sapiens]                       113   1e-25
gi|29244926 corin [Homo sapiens]                                      113   2e-25
gi|4506143 neurotrypsin precursor [Homo sapiens]                      110   8e-25
gi|110578663 hypothetical protein LOC203074 [Homo sapiens]            110   8e-25
gi|4506115 protein C [Homo sapiens]                                   109   2e-24
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   109   2e-24

>gi|148806923 testis serine protease 5 [Homo sapiens]
          Length = 228

 Score =  487 bits (1254), Expect = e-138
 Identities = 228/228 (100%), Positives = 228/228 (100%)

Query: 1   MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRAL 60
           MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRAL
Sbjct: 1   MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRAL 60

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPELQEAEVFIMDNKRCD 120
           WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPELQEAEVFIMDNKRCD
Sbjct: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPELQEAEVFIMDNKRCD 120

Query: 121 RHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACVK 180
           RHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACVK
Sbjct: 121 RHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACVK 180

Query: 181 AQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS 228
           AQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS
Sbjct: 181 AQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS 228


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  151 bits (381), Expect = 5e-37
 Identities = 88/240 (36%), Positives = 122/240 (50%), Gaps = 46/240 (19%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGT---KEYSVVLGTSKLQ-PMNFSRAL 60
           WPW+ SLR+   HVCGG+L+ P WV+TAAHC  G+    +Y V LG  ++    +FS   
Sbjct: 49  WPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFST-- 106

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPE--------------- 105
              VR II+H    G+    GD+ALV L  PVT SS    +  PE               
Sbjct: 107 ---VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTG 163

Query: 106 ---------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENLC 150
                          L+E +V ++D + C R Y      P   ++  DM+CA   G+  C
Sbjct: 164 WGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPG----PGGSILQPDMLCARGPGD-AC 218

Query: 151 YGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQM--SNGAFSG 208
             DSGGPL C+V G W+ AG++SW + C +   PGVYTR+  Y  WI++ +  S G+ SG
Sbjct: 219 QDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESG 278


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  145 bits (367), Expect = 2e-35
 Identities = 82/228 (35%), Positives = 124/228 (54%), Gaps = 37/228 (16%)

Query: 5   WPWEVSLRMENE---HVCGGALIDPSWVVTAAHCI-QGTKEYSVVLGTSKLQPMNFSRAL 60
           WPW+VSLR+ +    H CGG+LI P WV+TAAHC+    K+ + +    + Q + +   L
Sbjct: 42  WPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL 101

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTP---------------- 104
            +PV  II+HP+++  A I  D+AL+ L+ PV  SS  +++  P                
Sbjct: 102 -LPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTG 159

Query: 105 --------------ELQEAEVFIMDNKRCD-RHYKKSFFPPVVPLVLGDMICATNYGENL 149
                          L++ +V IM+N  CD +++  ++    V +V  DM+CA N   + 
Sbjct: 160 WGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDS 219

Query: 150 CYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI 197
           C GDSGGPL C+V G W+ AGV+SW + C +   PG+YTR+T Y  WI
Sbjct: 220 CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  145 bits (365), Expect = 4e-35
 Identities = 82/228 (35%), Positives = 123/228 (53%), Gaps = 37/228 (16%)

Query: 5   WPWEVSLRMENE---HVCGGALIDPSWVVTAAHCI-QGTKEYSVVLGTSKLQPMNFSRAL 60
           WPW+VSLR+      H CGG+LI P WV+TAAHC+    K+ + +    + Q + +   L
Sbjct: 42  WPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL 101

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTP---------------- 104
            +PV  II+HP+++  A I  D+AL+ L+ PV  SS  +++  P                
Sbjct: 102 -LPVSRIIVHPQFY-TAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTG 159

Query: 105 --------------ELQEAEVFIMDNKRCD-RHYKKSFFPPVVPLVLGDMICATNYGENL 149
                          L++ +V IM+N  CD +++  ++    V +V  DM+CA N   + 
Sbjct: 160 WGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDS 219

Query: 150 CYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI 197
           C GDSGGPL C+V G W+ AGV+SW + C +   PG+YTR+T Y  WI
Sbjct: 220 CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  142 bits (357), Expect = 3e-34
 Identities = 85/233 (36%), Positives = 117/233 (50%), Gaps = 37/233 (15%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGT---KEYSVVLGTSKLQPMNFSRALW 61
           WPW+VS+  E  HVCGG+L+   WV++AAHC       + Y V LG  +L   +   A  
Sbjct: 56  WPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYS-EDAKV 114

Query: 62  VPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSS--------TAN-------------- 99
             ++DII HP Y       GD+AL+ L  P+TFS          AN              
Sbjct: 115 STLKDIIPHPSYLQEGS-QGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGW 173

Query: 100 -------SMLTPE-LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--TNYGENL 149
                  S+LTP+ LQ+ EV ++  + C+  Y     P     V  DM+CA     G++ 
Sbjct: 174 GHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDA 233

Query: 150 CYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMS 202
           C GDSGGPL+C VEG W L G++SW  AC     PGVYT  + Y  WI+ +++
Sbjct: 234 CQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVT 286


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  134 bits (336), Expect = 8e-32
 Identities = 90/266 (33%), Positives = 128/266 (48%), Gaps = 49/266 (18%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKEYS------VVLGTSKLQPMNFSR 58
           WPW+ SLR+ + HVCG +L+   W +TAAHC +   + S      V  G     P  +S 
Sbjct: 53  WPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSL 112

Query: 59  ALWVP---VRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTAN---------------- 99
             +     V +I + P+Y G +    D+ALV L  PVT++                    
Sbjct: 113 QAYYTRYFVSNIYLSPRYLGNSPY--DIALVKLSAPVTYTKHIQPICLQASTFEFENRTD 170

Query: 100 -------------SMLTPE-LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNY 145
                        ++ +P  LQE +V I++N  C+  + K  F   +    GDM+CA N 
Sbjct: 171 CWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDI---FGDMVCAGNA 227

Query: 146 --GENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSN 203
             G++ C+GDSGGPLAC   G W   GV+SW   C +   PGVYT I+ + +WI+K M+ 
Sbjct: 228 QGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQ 287

Query: 204 GAFSGPCASACLLF--LCWLLQPQMG 227
              S P  S  LLF  L W L P +G
Sbjct: 288 SGMSQPDPSWPLLFFPLLWAL-PLLG 312


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  133 bits (335), Expect = 1e-31
 Identities = 85/232 (36%), Positives = 115/232 (49%), Gaps = 40/232 (17%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKE---YSVVLGTSKL-QPMNFSRAL 60
           WPW+VS++    H CGG+LI   WV+TAAHC + T E   Y V+LG  +L QP     A+
Sbjct: 46  WPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPG--PHAM 103

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFS------------------------- 95
           +  VR +  +P Y G A    DVALV L+ PV F+                         
Sbjct: 104 YARVRQVESNPLYQGTAS-SADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTG 162

Query: 96  --STANSMLTPE---LQEAEVFIMDNKRCDRHYKKSF-FPPVVPLVLGDMICA--TNYGE 147
             S +   L PE   LQ+  V I+D  +C+  Y K   F      +  DM+CA      +
Sbjct: 163 WGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKK 222

Query: 148 NLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKK 199
           + C GDSGGPL C V   W+ AGV+SW + C +   PGVY R+T +  WI +
Sbjct: 223 DACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHR 274


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  133 bits (334), Expect = 1e-31
 Identities = 81/233 (34%), Positives = 117/233 (50%), Gaps = 39/233 (16%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGT-KEYSVVLGTSKLQPMNFSRALWVP 63
           WPW+VSL  ++  +CGG+L+    ++TAAHCIQ T   +S  +    +   +  + +   
Sbjct: 39  WPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRVKYY 98

Query: 64  VRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPE------------------ 105
           V  I++HPKY        DVAL+ L + VTF+S    +  P                   
Sbjct: 99  VSKIVIHPKYQDTT---ADVALLKLSSQVTFTSAILPICLPSVTKQLAIPPFCWVTGWGK 155

Query: 106 ------------LQEAEVFIMDNKRCDRHYKK--SFFPPVVPLVLGDMICA--TNYGENL 149
                       LQEAEV I+D + C++ Y     F P + P++  D ICA  T   ++ 
Sbjct: 156 VKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDS 215

Query: 150 CYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMS 202
           C GDSGGPL+C ++G WI  GV+SW   C K+  PGVYT +  Y KWI   +S
Sbjct: 216 CKGDSGGPLSCHIDGVWIQTGVVSWGLECGKSL-PGVYTNVIYYQKWINATIS 267


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  133 bits (334), Expect = 1e-31
 Identities = 89/264 (33%), Positives = 127/264 (48%), Gaps = 47/264 (17%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQ----GTKEYSVVLGTSKLQPMNFSRAL 60
           WPW+ SLR+ + HVCG +L+   W +TAAHC +        + V  G     P  +S   
Sbjct: 53  WPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPSFWSLQA 112

Query: 61  WVP---VRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTAN------------------ 99
           +     V +I + P+Y G +    D+ALV L  PVT++                      
Sbjct: 113 YYTRYFVSNIYLSPRYLGNSPY--DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCW 170

Query: 100 -----------SMLTPE-LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNY-- 145
                      ++ +P  LQE +V I++N  C+  + K  F   +    GDM+CA N   
Sbjct: 171 VTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDI---FGDMVCAGNAQG 227

Query: 146 GENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSNGA 205
           G++ C+GDSGGPLAC   G W   GV+SW   C +   PGVYT I+ + +WI+K M+   
Sbjct: 228 GKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSG 287

Query: 206 FSGPCASACLLF--LCWLLQPQMG 227
            S P  S  LLF  L W L P +G
Sbjct: 288 MSQPDPSWPLLFFPLLWAL-PLLG 310


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  131 bits (329), Expect = 5e-31
 Identities = 88/259 (33%), Positives = 130/259 (50%), Gaps = 45/259 (17%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQG---TKEYSVVLG--TSKLQPMNF-SR 58
           WPW+ SLR+   H CGG+L+   WV++AAHC Q      E++V LG  TS+  P N  + 
Sbjct: 66  WPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLRAY 125

Query: 59  ALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTF----------SSTANSMLTPE--- 105
           +    V+DII++P   G   +  D+AL+ L + VT+          SST N +  P+   
Sbjct: 126 SSRYKVQDIIVNPDALG--VLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWV 183

Query: 106 ------------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--TNY 145
                             L+EA+V I++N RC+  +++   P    ++   M CA   + 
Sbjct: 184 TGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQ---PSSRSMIWDSMFCAGAEDG 240

Query: 146 GENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSNGA 205
             + C GDSGGPL C+ +G W   G++SW   C +   PGVYT I+ Y  WI++ MS+  
Sbjct: 241 SVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHST 300

Query: 206 FSGPCASACLLFLCWLLQP 224
              P  S  LL L  L  P
Sbjct: 301 -PRPNPSQLLLLLALLWAP 318


>gi|7019563 testes-specific protease 50 [Homo sapiens]
          Length = 385

 Score =  130 bits (328), Expect = 7e-31
 Identities = 78/254 (30%), Positives = 118/254 (46%), Gaps = 39/254 (15%)

Query: 1   MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAHC-IQGTKEYSVVLGTSKLQPMNFSRA 59
           + R WPW VS+R    H+C G +I   WV+T AHC I     YSV +G+  +  M    A
Sbjct: 120 VARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMT-QTA 178

Query: 60  LWVPVRDIIMHPKY-----WGRAFIMGDVALVHLQTPVTFSSTANSMLTP---------- 104
             VPV  +IMH +Y     W       D+ L+ L+  + +S+    +  P          
Sbjct: 179 SDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHS 238

Query: 105 --------------------ELQEAEVFIMDNKRCDRHYKK-SFFPPVVPLVLGDMICAT 143
                                +QE EV I++NK CD  Y   +  P +V ++   M+CA 
Sbjct: 239 RCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAE 298

Query: 144 N-YGENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMS 202
           + + E  CY  +G PL C +EG W L G++SW   C K++ P +Y +++ Y  WI   ++
Sbjct: 299 DTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLN 358

Query: 203 NGAFSGPCASACLL 216
             A + P  S  LL
Sbjct: 359 GQALALPAPSRTLL 372


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  125 bits (313), Expect = 4e-29
 Identities = 75/233 (32%), Positives = 110/233 (47%), Gaps = 43/233 (18%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKE-----YSVVLGTSKLQPMNFSRA 59
           WPW+VSL     H+CGG LID  WV+TAAHC   T+E     + V  GTS L  +  + +
Sbjct: 337 WPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAAS 396

Query: 60  LWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSS----------------------- 96
               + +II++  Y        D+AL+ L  P+T S+                       
Sbjct: 397 ----IAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWIT 451

Query: 97  ------TANSMLTPELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENLC 150
                   +   +P L+E +V ++D K+C+ +     +     +  GD+      G + C
Sbjct: 452 GFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDL----RGGRDSC 507

Query: 151 YGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSN 203
            GDSGGPL CE   RW LAGV SW   C +   PGVYT++T+   WI  +M +
Sbjct: 508 QGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  123 bits (308), Expect = 1e-28
 Identities = 77/227 (33%), Positives = 112/227 (49%), Gaps = 40/227 (17%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRALWVPV 64
           WPW+VSLR+ N H CGG+LI+  W++TAAHC +        + TS +    F + L + V
Sbjct: 198 WPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIS-TTFPK-LRMRV 255

Query: 65  RDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSM----------------------- 101
           R+I++H  Y   A    D+ALV L+  VTF+   +S+                       
Sbjct: 256 RNILIHNNY-KSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQ 314

Query: 102 -----LTPELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--TNYGENLCYGDS 154
                  PEL++ +V I+ N  C+  +  +        +L  M+CA     G + C GDS
Sbjct: 315 EYAGHTVPELRQGQVRIISNDVCNAPHSYN------GAILSGMLCAGVPQGGVDACQGDS 368

Query: 155 GGPLACEVEGR-WILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQ 200
           GGPL  E   R W + G++SW   C     PGVYTR+T Y  WI++Q
Sbjct: 369 GGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQ 415


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  122 bits (306), Expect = 3e-28
 Identities = 77/231 (33%), Positives = 106/231 (45%), Gaps = 43/231 (18%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQ----GTKEYSVVLGTSKLQPMNFSRAL 60
           WPW+VSL ++N HVCGG++I P W+VTAAHC++        ++   G  +   M +    
Sbjct: 304 WPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAG- 362

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSS--------TANSMLTPE------- 105
              V  +I HP Y  +     D+AL+ LQ P+TF+             ML PE       
Sbjct: 363 -YQVEKVISHPNYDSKT-KNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISG 420

Query: 106 -------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENL--C 150
                        L  A+V +++ +RC+  Y          L+   MICA     N+  C
Sbjct: 421 WGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYD------NLITPAMICAGFLQGNVDSC 474

Query: 151 YGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQM 201
            GDSGGPL       W L G  SW   C KA  PGVY  +  +T WI +QM
Sbjct: 475 QGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQM 525


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  122 bits (306), Expect = 3e-28
 Identities = 77/231 (33%), Positives = 106/231 (45%), Gaps = 43/231 (18%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQ----GTKEYSVVLGTSKLQPMNFSRAL 60
           WPW+VSL ++N HVCGG++I P W+VTAAHC++        ++   G  +   M +    
Sbjct: 267 WPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAG- 325

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSS--------TANSMLTPE------- 105
              V  +I HP Y  +     D+AL+ LQ P+TF+             ML PE       
Sbjct: 326 -YQVEKVISHPNYDSKT-KNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISG 383

Query: 106 -------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENL--C 150
                        L  A+V +++ +RC+  Y          L+   MICA     N+  C
Sbjct: 384 WGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYD------NLITPAMICAGFLQGNVDSC 437

Query: 151 YGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQM 201
            GDSGGPL       W L G  SW   C KA  PGVY  +  +T WI +QM
Sbjct: 438 QGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQM 488


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  122 bits (306), Expect = 3e-28
 Identities = 73/227 (32%), Positives = 110/227 (48%), Gaps = 39/227 (17%)

Query: 3   RHWPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKE---YSVVLGTSKLQPMNFSRA 59
           R WPW+VS+     HVCGG++++  WV++AAHC    K    Y + +G   L+    +  
Sbjct: 69  RKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAG-NHT 127

Query: 60  LWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFS---------------STANSMLT- 103
            W  V  +I+HP Y     I GDVALV L+T + FS               ++AN   T 
Sbjct: 128 QWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSANCWATG 187

Query: 104 -----------PELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNY--GENLC 150
                       ELQE ++ ++    C   Y    +      ++ DM+CA +    + +C
Sbjct: 188 WGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSY------IMPDMLCAGDILNAKTVC 241

Query: 151 YGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI 197
            GDSGGPL CE    W+  G++SW + C     PGVY  ++ ++KWI
Sbjct: 242 EGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  119 bits (297), Expect = 3e-27
 Identities = 72/225 (32%), Positives = 107/225 (47%), Gaps = 41/225 (18%)

Query: 5   WPWEVSLRMENE-HVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRALWVP 63
           WPW+VSL+ +   H CGG+LI   WVVTAAHC  G +   VV+     Q  +      + 
Sbjct: 45  WPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLK 102

Query: 64  VRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTP------------------- 104
           +  +  +PK+     +  D+ L+ L TP  FS T +++  P                   
Sbjct: 103 IAKVFKNPKF-SILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGK 161

Query: 105 ----------ELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDS 154
                     +LQ+A + ++ N  C    KKS+   +  +    MICA   G + C GDS
Sbjct: 162 TKYNANKTPDKLQQAALPLLSNAEC----KKSWGRRITDV----MICAGASGVSSCMGDS 213

Query: 155 GGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKK 199
           GGPL C+ +G W L G++SW        +PGVY R+TK   W++K
Sbjct: 214 GGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQK 258


>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score =  118 bits (296), Expect = 4e-27
 Identities = 76/224 (33%), Positives = 108/224 (48%), Gaps = 40/224 (17%)

Query: 5    WPWEVSLRME-NEHVCGGALIDPSWVVTAAHCIQGTKE---YSVVLGT-------SKLQP 53
            WPW+VSLR    +H CGG LI P WV+TAAHC++ +     Y V+LG        S +Q 
Sbjct: 1831 WPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQE 1890

Query: 54   MNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTP------------VTFSSTANSM 101
            +  SR    P +  I   K    A I   V    L +P              +  T  + 
Sbjct: 1891 IEVSRLFLEPTQADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTF 1950

Query: 102  LTPELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNY--GENLCYGDSGGPLA 159
             T  L+EA++ +++N+ C+ HYK               ICA +   G + C GDSGGPL 
Sbjct: 1951 GTGLLKEAQLLVIENEVCN-HYK--------------YICAEHLARGTDSCQGDSGGPLV 1995

Query: 160  CEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSN 203
            C  + ++IL GV SW   C +   PGVY R++++  WI+  M N
Sbjct: 1996 CFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRN 2039


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  117 bits (294), Expect = 6e-27
 Identities = 74/242 (30%), Positives = 117/242 (48%), Gaps = 55/242 (22%)

Query: 5   WPWEVSLRME---NEHVCGGALIDPSWVVTAAHCIQGT------KEYSVVLGTSKL-QPM 54
           WPW+VSL+++     H+CGG+LI   WV+TAAHC  G       + YS +L  S + +  
Sbjct: 402 WPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDT 461

Query: 55  NFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPE--------- 105
            FS+     +++II+H  Y   +    D+AL+ LQ P+ ++     +  P          
Sbjct: 462 PFSQ-----IKEIIIHQNY-KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYT 515

Query: 106 -------------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--TN 144
                              LQ+  + ++ N+ C + Y+          +   M+CA    
Sbjct: 516 NCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY-------KITQRMVCAGYKE 568

Query: 145 YGENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI--KKQMS 202
            G++ C GDSGGPL C+  G W L G+ SW + C + + PGVYT++ +Y  WI  K Q S
Sbjct: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628

Query: 203 NG 204
           +G
Sbjct: 629 DG 630


>gi|33186882 testis serine protease 2 [Homo sapiens]
          Length = 293

 Score =  115 bits (289), Expect = 2e-26
 Identities = 65/204 (31%), Positives = 99/204 (48%), Gaps = 33/204 (16%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRALWVPV 64
           WPW+VS+R +  H+CGG L+  +WV+TA HCI     YSV +G   +   N S  + V V
Sbjct: 91  WPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTS--VVVSV 148

Query: 65  RDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPE------------------- 105
           +   +HPK+     I  D+AL+ LQ PV F+S    +  P+                   
Sbjct: 149 QRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKT 208

Query: 106 ----------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA-TNYGENLCYGDS 154
                     LQ+ + +IM  + C++  +K+       ++ G M+C     G++ C GDS
Sbjct: 209 PEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKG-MVCGYKEQGKDSCQGDS 267

Query: 155 GGPLACEVEGRWILAGVLSWEKAC 178
           GG LACE    W+  G++SW   C
Sbjct: 268 GGRLACEYNDTWVQVGIVSWGIGC 291


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  114 bits (285), Expect = 7e-26
 Identities = 73/222 (32%), Positives = 105/222 (47%), Gaps = 27/222 (12%)

Query: 5   WPWEVSLRME-NEHVCGGALIDPSWVVTAAHCIQGT---KEYSVVLGTSK-------LQP 53
           WPW+VSLR     H CGG LI P WV+TAAHC++ +     Y V+LG  +       +Q 
Sbjct: 592 WPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQE 651

Query: 54  MNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTP------------VTFSSTANSM 101
           +  SR    P R  I   K    A I   V    L +P              +  T  + 
Sbjct: 652 IEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTF 711

Query: 102 LTPELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACE 161
               L+EA++ +++NK C+R+   +       L  G +   T+     C GDSGGPL C 
Sbjct: 712 GAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDS----CQGDSGGPLVCF 767

Query: 162 VEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSN 203
            + ++IL GV SW   C +   PGVY R++++  WI+  M N
Sbjct: 768 EKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRN 809


>gi|118498350 chymotrypsin B2 [Homo sapiens]
          Length = 263

 Score =  114 bits (285), Expect = 7e-26
 Identities = 70/225 (31%), Positives = 104/225 (46%), Gaps = 41/225 (18%)

Query: 5   WPWEVSLRMENE-HVCGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRALWVP 63
           WPW+VSL+ +   H CGG+LI   WVVTAAHC  G +   VV+     Q  +      + 
Sbjct: 45  WPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLK 102

Query: 64  VRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTP------------------- 104
           +  +  +PK+     +  D+ L+ L TP  FS T +++  P                   
Sbjct: 103 IAKVFKNPKF-SILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGK 161

Query: 105 ----------ELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDS 154
                     +LQ+A + ++ N  C    KKS+   +  +    MICA   G + C GDS
Sbjct: 162 TKYNANKTPDKLQQAALPLLSNAEC----KKSWGRRITDV----MICAGASGVSSCMGDS 213

Query: 155 GGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKK 199
           GGPL C+ +G W L G++SW         P VY R+ K   W++K
Sbjct: 214 GGPLVCQKDGAWTLVGIVSWGSRTCSTTTPAVYARVAKLIPWVQK 258


>gi|4503137 chymotrypsin-like [Homo sapiens]
          Length = 264

 Score =  114 bits (284), Expect = 9e-26
 Identities = 73/232 (31%), Positives = 108/232 (46%), Gaps = 54/232 (23%)

Query: 5   WPWEVSLRMENE-HVCGGALIDPSWVVTAAHCIQGTKEYSVVLG-------TSKLQPMNF 56
           WPW+VSL+  +  H CGG+LI  SWVVTAAHC      + VVLG          LQ ++ 
Sbjct: 45  WPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSV 104

Query: 57  SRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSS--------TANSMLTP---- 104
           SRA        I HP  W    +  DV L+ L +P  +++        ++N  LT     
Sbjct: 105 SRA--------ITHPS-WNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTC 155

Query: 105 -----------------ELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGE 147
                             LQ+  + ++   +C +++  S        +   MICA   G 
Sbjct: 156 VTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSS--------ITDSMICAGGAGA 207

Query: 148 NLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKK 199
           + C GDSGGPL C+    W+L G++SW       + P VYTR++K++ WI +
Sbjct: 208 SSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQ 259


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  113 bits (283), Expect = 1e-25
 Identities = 68/232 (29%), Positives = 112/232 (48%), Gaps = 51/232 (21%)

Query: 5   WPWEVSLRMEN---EHVCGGALIDPSWVVTAAHCIQGTKE------YSVVLGTSKLQPMN 55
           WPW+V+L   +    H+CGG++I   W++TAAHC  G +       YS +L  S+++   
Sbjct: 399 WPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIK--- 455

Query: 56  FSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPE---------- 105
                +  V++II+H +Y   A    D+AL+ L+T V ++ +   +  P           
Sbjct: 456 -EDTSFFGVQEIIIHDQY-KMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTD 513

Query: 106 ------------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--TNY 145
                             LQ+A++ ++ N+ C + Y+          +   MICA     
Sbjct: 514 CWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGH-------KITHKMICAGYREG 566

Query: 146 GENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI 197
           G++ C GDSGGPL+C+    W L G+ SW + C + + PGVYT + +Y  WI
Sbjct: 567 GKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  113 bits (283), Expect = 1e-25
 Identities = 76/245 (31%), Positives = 115/245 (46%), Gaps = 45/245 (18%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHC------IQGTKEYSVVLGT-SKLQPMNFS 57
           WPW+VSL     H+CGG+LI PSWV++AAHC      ++   E+SV+LG  S+  P++ +
Sbjct: 58  WPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGA 117

Query: 58  RALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTPE------------ 105
               V     I+ P  + +  +  D+AL+ L +P +       +  P             
Sbjct: 118 HTRAVAA---IVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACW 174

Query: 106 ------------------LQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGE 147
                             LQE E+ ++    C   Y +     +   +L  M+CA  Y E
Sbjct: 175 ATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCA-GYPE 233

Query: 148 ---NLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSNG 204
              + C GDSGGPL CE  GRW  AG+ S+   C +   PGV+T +  Y  WI++Q+  G
Sbjct: 234 GRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVM-G 292

Query: 205 AFSGP 209
           +  GP
Sbjct: 293 SEPGP 297



 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 56/235 (23%), Positives = 87/235 (37%), Gaps = 43/235 (18%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHC-IQGTKEYSVVLGTSKLQPMNFSRALWVP 63
           WPWE  + +     C GAL+  SWV+  A C +      S        + +  SR     
Sbjct: 334 WPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAER 393

Query: 64  VRDIIMHPK-YWGRAFIMGDVALVHLQTPVTFSSTANSMLTPELQEAEVFIMDNKRCDRH 122
           V  ++ H    W  A    D+AL+ L+TPV  S+ +  +  P     E + +   RC   
Sbjct: 394 VARLVQHENASWDNA---SDLALLQLRTPVNLSAASRPVCLP---HPEHYFLPGSRCRLA 447

Query: 123 YKKSFFPPVVP------LVLGDMICATNYGE-------------------------NLCY 151
                 P + P       +LG   C   YG                            C+
Sbjct: 448 RWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCW 507

Query: 152 GDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSNGAF 206
            DS   L C+ EG W LAG+  +   C++   P  +  +  +  WI   ++ GA+
Sbjct: 508 NDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWI-SHVTRGAY 558



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 63/238 (26%), Positives = 92/238 (38%), Gaps = 50/238 (21%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCI----QGTKEYSVV----LGTSKLQPMNF 56
           WPW   + +  + VC G L+ P WV+ A HC+      T  Y  V     G S L   + 
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660

Query: 57  SRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSM-LTP----------- 104
              L + +R     P++ G   +   +AL+ L + V  S +A  + L P           
Sbjct: 661 VSRLVISIR----LPQHLG---LRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWV 713

Query: 105 ----ELQE-----AEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSG 155
               E Q+     A V I+  + CD  Y +   PP    VL          EN C   S 
Sbjct: 714 LGWKEPQDRVPVAAAVSILTQRICDCLY-QGILPPGTLCVL-----YAEGQENRCEMTSA 767

Query: 156 GPLACEV-EGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSNGAFSGPCAS 212
            PL C++ EG WIL G+       V+     ++  I     WI + +    F  P  S
Sbjct: 768 PPLLCQMTEGSWILVGM------AVQGSRE-LFAAIGPEEAWISQTVGEANFLPPSGS 818


>gi|29244926 corin [Homo sapiens]
          Length = 1042

 Score =  113 bits (282), Expect = 2e-25
 Identities = 75/232 (32%), Positives = 113/232 (48%), Gaps = 45/232 (19%)

Query: 5    WPWEVSLRME-NEHVCGGALIDPSWVVTAAHCIQGTKE---YSVVLGTSKL-QPMNFSRA 59
            WPW+ SL+ E + H+CG  LI   WV+T AHC +G +    + VVLG + L  P  F + 
Sbjct: 813  WPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQT 872

Query: 60   LWVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTP--------------- 104
             +  V+ II+HP+Y  RA +  D+++V L   ++ +     +  P               
Sbjct: 873  RF--VKTIILHPRY-SRAVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYIT 929

Query: 105  -----------ELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICATNYGENL--CY 151
                       +LQE EV I+  + C  ++        +  +   MICA      +  C 
Sbjct: 930  GWGHMGNKMPFKLQEGEVRIISLEHCQSYFD-------MKTITTRMICAGYESGTVDSCM 982

Query: 152  GDSGGPLACEVE-GRWILAGVLSWEKACV-KAQNPGVYTRITKYTKWIKKQM 201
            GDSGGPL CE   GRW L G+ SW   C  K   PGVY+ ++ + +WIK+Q+
Sbjct: 983  GDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQI 1034


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  110 bits (276), Expect = 8e-25
 Identities = 79/240 (32%), Positives = 113/240 (47%), Gaps = 57/240 (23%)

Query: 5   WPWEVSLRMENEH-----VCGGALIDPSWVVTAAHCIQ----GTKEYSVVLGT-SKLQPM 54
           WPW+VSLR+++ H     +CG  L+   WV+TAAHC +     T+ Y+V +G    L P 
Sbjct: 642 WPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPE 701

Query: 55  NFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQTP----VTFSS-------------- 96
            F     + V+ I++H +Y        D+ALV LQ P      FSS              
Sbjct: 702 EFEEE--IGVQQIVIHREYRPDRSDY-DIALVRLQGPEEQCARFSSHVLPACLPLWRERP 758

Query: 97  ---TANSMLT----------PELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICAT 143
               +N  +T            LQ+A + ++  + C+  YK  F         G M+CA 
Sbjct: 759 QKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRF--------TGRMLCAG 810

Query: 144 NYGE----NLCYGDSGGPLACEVEGR-WILAGVLSWEKACVKAQNPGVYTRITKYTKWIK 198
           N  E    + C GDSGGPL CE  G  W++ GV SW   C    +PGVYT+++ +  WIK
Sbjct: 811 NLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWIK 870


>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
          Length = 352

 Score =  110 bits (276), Expect = 8e-25
 Identities = 73/233 (31%), Positives = 116/233 (49%), Gaps = 52/233 (22%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTK----EYSVVLGTSKLQPMNFSRAL 60
           +PW+VS++  +E  CGG++++  W++TAAHC+   +    E SVVLGT+ L   +     
Sbjct: 79  FPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIK- 137

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPV---------------------------- 92
              V  II+H K + RA +  D+AL+ L +P+                            
Sbjct: 138 --EVASIILH-KDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGW 194

Query: 93  --TFSSTANSMLTPELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--TNYGEN 148
             T ++  NS+ T +L +A + IMD + C + +         P +  +M+CA   N   +
Sbjct: 195 GQTNAADKNSVKT-DLMKAPMVIMDWEECSKMF---------PKLTKNMLCAGYKNESYD 244

Query: 149 LCYGDSGGPLACEVEG--RWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKK 199
            C GDSGGPL C  E   +W   G++SW K+C +   PG+YT +  Y  WI+K
Sbjct: 245 ACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEK 297


>gi|4506115 protein C [Homo sapiens]
          Length = 461

 Score =  109 bits (272), Expect = 2e-24
 Identities = 73/224 (32%), Positives = 111/224 (49%), Gaps = 34/224 (15%)

Query: 6   PWEVSLRMENEHV-CGGALIDPSWVVTAAHCIQGTKEYSVVLGTSKLQPMNFSRALWVPV 64
           PW+V L    + + CG  LI PSWV+TAAHC+  +K+  V LG   L+       L + +
Sbjct: 224 PWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWE-KWELDLDI 282

Query: 65  RDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSMLTP-------ELQEA--EVFIMD 115
           +++ +HP Y  ++    D+AL+HL  P T S T   +  P       EL +A  E  +  
Sbjct: 283 KEVFVHPNY-SKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTG 341

Query: 116 ---------NKRCDRHYKKSFFP-PVVP----------LVLGDMICATNYGE--NLCYGD 153
                      + +R +  +F   PVVP          +V  +M+CA   G+  + C GD
Sbjct: 342 WGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGD 401

Query: 154 SGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI 197
           SGGP+     G W L G++SW + C    N GVYT++++Y  WI
Sbjct: 402 SGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWI 445


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  109 bits (272), Expect = 2e-24
 Identities = 74/230 (32%), Positives = 112/230 (48%), Gaps = 53/230 (23%)

Query: 5   WPWEVSLRMENEHVCGGALIDPSWVVTAAHCIQGTKE---YSVVLGTSKLQPM-NFSRAL 60
           WPW+VS++ + +HVCGG+++DP WV+TAAHC +   +   + V  G+ KL    + + A 
Sbjct: 211 WPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAK 270

Query: 61  WVPVRDIIMHPKYWGRAFIMGDVALVHLQTPVTFSSTANSM--------LTPE------- 105
            + +    M+PK         D+AL+ LQ P+TFS T   +        LTP        
Sbjct: 271 IIIIEFNPMYPKD-------NDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIG 323

Query: 106 --------------LQEAEVFIMDNKRC--DRHYKKSFFPPVVPLVLGDMICA--TNYGE 147
                         L +A V ++D+ RC  D  Y+          V   M+CA     G 
Sbjct: 324 WGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGE--------VTEKMMCAGIPEGGV 375

Query: 148 NLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWI 197
           + C GDSGGPL  + + +W + G++SW   C     PGVYT+++ Y  WI
Sbjct: 376 DTCQGDSGGPLMYQSD-QWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,798,764
Number of Sequences: 37866
Number of extensions: 429448
Number of successful extensions: 1193
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 667
Number of HSP's gapped (non-prelim): 284
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.