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Search of human proteins with 148746220
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148746220 spermatogenesis associated, serine-rich 2 [Homo
sapiens]
(545 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148746220 spermatogenesis associated, serine-rich 2 [Homo sap... 1069 0.0
gi|154426288 SPATS2-like protein isoform a [Homo sapiens] 322 4e-88
gi|154426253 SPATS2-like protein isoform a [Homo sapiens] 322 4e-88
gi|154426310 SPATS2-like protein isoform a [Homo sapiens] 322 4e-88
gi|154426312 SPATS2-like protein isoform b [Homo sapiens] 300 2e-81
gi|87299628 biorientation of chromosomes in cell division 1-like... 43 8e-04
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 42 0.001
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 42 0.002
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 41 0.002
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 40 0.004
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 40 0.007
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 40 0.007
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 40 0.007
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 40 0.007
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 40 0.007
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.009
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 39 0.012
gi|33356179 transcription termination factor, RNA polymerase I [... 38 0.021
gi|239752579 PREDICTED: hypothetical protein XP_002348295 [Homo ... 38 0.021
gi|239746945 PREDICTED: SAGE1-like protein-like [Homo sapiens] 38 0.027
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 38 0.027
gi|34878777 ring finger protein 20 [Homo sapiens] 37 0.035
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 37 0.046
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 37 0.061
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 37 0.061
gi|28559039 mediator complex subunit 1 [Homo sapiens] 37 0.061
gi|7705415 hook homolog 1 [Homo sapiens] 37 0.061
gi|55770834 centromere protein F [Homo sapiens] 37 0.061
gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens] 36 0.079
gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens] 36 0.079
>gi|148746220 spermatogenesis associated, serine-rich 2 [Homo
sapiens]
Length = 545
Score = 1069 bits (2765), Expect = 0.0
Identities = 545/545 (100%), Positives = 545/545 (100%)
Query: 1 MSRKQNQKDSSGFIFDLQSNTVLAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDN 60
MSRKQNQKDSSGFIFDLQSNTVLAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDN
Sbjct: 1 MSRKQNQKDSSGFIFDLQSNTVLAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDN 60
Query: 61 CVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQS 120
CVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQS
Sbjct: 61 CVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQS 120
Query: 121 APSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQ 180
APSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQ
Sbjct: 121 APSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQ 180
Query: 181 NGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEK 240
NGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEK
Sbjct: 181 NGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEK 240
Query: 241 SVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAM 300
SVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAM
Sbjct: 241 SVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAM 300
Query: 301 EILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVET 360
EILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVET
Sbjct: 301 EILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVET 360
Query: 361 LKKSIDSFGQVSHPKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNF 420
LKKSIDSFGQVSHPKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNF
Sbjct: 361 LKKSIDSFGQVSHPKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNF 420
Query: 421 APGETPAAIANSSGQPYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSS 480
APGETPAAIANSSGQPYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSS
Sbjct: 421 APGETPAAIANSSGQPYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSS 480
Query: 481 WYSSGSRYQSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPRTSQT 540
WYSSGSRYQSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPRTSQT
Sbjct: 481 WYSSGSRYQSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPRTSQT 540
Query: 541 EAVNS 545
EAVNS
Sbjct: 541 EAVNS 545
>gi|154426288 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 322 bits (826), Expect = 4e-88
Identities = 214/535 (40%), Positives = 305/535 (57%), Gaps = 35/535 (6%)
Query: 23 LAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWT 82
+A+ N+KEKI AVR++VPNKSNNEI+LVLQ FD VDK VQAF++GSA +VLKEW
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 83 VTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTE 142
+TGKKKN K+K + + D + Q P + G +NG D+
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGP----MNGCEKDSS 116
Query: 143 SVDSLSEGLETLSIDARE--LEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHN-- 198
S DS +E + + + LE+P A+ + + Q D K + + +
Sbjct: 117 STDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDG 176
Query: 199 ----SQQPRNAAKSLSRPT-TETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLA 253
++QP N +K ++ + ++ +E P +KK NIEKSVKDLQRCTVSL
Sbjct: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
Query: 254 RYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELL 313
RYRV++KEE+D+S+KK+K AFAEL +C++D+EV+L+AEMDKVK EAMEIL +RQKKAE L
Sbjct: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
Query: 314 KKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSH 373
K++T +A QM+E QL ELRA+IKHFVSERKYDE+LG+ ARF+CD+E LK I G+++H
Sbjct: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
Query: 374 PKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IA 430
PKN+YS+R+ CSS+ + +A AA+S ++ +S + K P E AA +
Sbjct: 357 PKNNYSSRTPCSSLLPL-----LNAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMV 408
Query: 431 NSSGQPYQPLREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-S 486
+S P + +P N++ G Q R Q N+ +N G S G + G S
Sbjct: 409 SSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNS 467
Query: 487 RYQSAPSQAPGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQT 540
R++ + P N A + M+ P P S K P+R+ + T
Sbjct: 468 RHEH--RRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADT 517
>gi|154426253 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 322 bits (826), Expect = 4e-88
Identities = 214/535 (40%), Positives = 305/535 (57%), Gaps = 35/535 (6%)
Query: 23 LAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWT 82
+A+ N+KEKI AVR++VPNKSNNEI+LVLQ FD VDK VQAF++GSA +VLKEW
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 83 VTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTE 142
+TGKKKN K+K + + D + Q P + G +NG D+
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGP----MNGCEKDSS 116
Query: 143 SVDSLSEGLETLSIDARE--LEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHN-- 198
S DS +E + + + LE+P A+ + + Q D K + + +
Sbjct: 117 STDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDG 176
Query: 199 ----SQQPRNAAKSLSRPT-TETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLA 253
++QP N +K ++ + ++ +E P +KK NIEKSVKDLQRCTVSL
Sbjct: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
Query: 254 RYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELL 313
RYRV++KEE+D+S+KK+K AFAEL +C++D+EV+L+AEMDKVK EAMEIL +RQKKAE L
Sbjct: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
Query: 314 KKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSH 373
K++T +A QM+E QL ELRA+IKHFVSERKYDE+LG+ ARF+CD+E LK I G+++H
Sbjct: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
Query: 374 PKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IA 430
PKN+YS+R+ CSS+ + +A AA+S ++ +S + K P E AA +
Sbjct: 357 PKNNYSSRTPCSSLLPL-----LNAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMV 408
Query: 431 NSSGQPYQPLREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-S 486
+S P + +P N++ G Q R Q N+ +N G S G + G S
Sbjct: 409 SSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNS 467
Query: 487 RYQSAPSQAPGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQT 540
R++ + P N A + M+ P P S K P+R+ + T
Sbjct: 468 RHEH--RRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADT 517
>gi|154426310 SPATS2-like protein isoform a [Homo sapiens]
Length = 558
Score = 322 bits (826), Expect = 4e-88
Identities = 214/535 (40%), Positives = 305/535 (57%), Gaps = 35/535 (6%)
Query: 23 LAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWT 82
+A+ N+KEKI AVR++VPNKSNNEI+LVLQ FD VDK VQAF++GSA +VLKEW
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 83 VTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTE 142
+TGKKKN K+K + + D + Q P + G +NG D+
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGP----MNGCEKDSS 116
Query: 143 SVDSLSEGLETLSIDARE--LEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHN-- 198
S DS +E + + + LE+P A+ + + Q D K + + +
Sbjct: 117 STDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDG 176
Query: 199 ----SQQPRNAAKSLSRPT-TETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLA 253
++QP N +K ++ + ++ +E P +KK NIEKSVKDLQRCTVSL
Sbjct: 177 LQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLT 236
Query: 254 RYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELL 313
RYRV++KEE+D+S+KK+K AFAEL +C++D+EV+L+AEMDKVK EAMEIL +RQKKAE L
Sbjct: 237 RYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEEL 296
Query: 314 KKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSH 373
K++T +A QM+E QL ELRA+IKHFVSERKYDE+LG+ ARF+CD+E LK I G+++H
Sbjct: 297 KRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITH 356
Query: 374 PKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IA 430
PKN+YS+R+ CSS+ + +A AA+S ++ +S + K P E AA +
Sbjct: 357 PKNNYSSRTPCSSLLPL-----LNAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMV 408
Query: 431 NSSGQPYQPLREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-S 486
+S P + +P N++ G Q R Q N+ +N G S G + G S
Sbjct: 409 SSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNS 467
Query: 487 RYQSAPSQAPGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQT 540
R++ + P N A + M+ P P S K P+R+ + T
Sbjct: 468 RHEH--RRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADT 517
>gi|154426312 SPATS2-like protein isoform b [Homo sapiens]
Length = 489
Score = 300 bits (769), Expect = 2e-81
Identities = 205/526 (38%), Positives = 284/526 (53%), Gaps = 86/526 (16%)
Query: 23 LAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWT 82
+A+ N+KEKI AVR++VPNKSNNEI+LVLQ FD VDK VQAF++GSA +VLKEW
Sbjct: 1 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 60
Query: 83 VTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTE 142
+TGKKKN K+K + + D + Q P + G +NG D+
Sbjct: 61 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGP----MNGCEKDSS 116
Query: 143 SVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQP 202
S DS + E L ++ S+L+ +P
Sbjct: 117 STDSAN----------------EKPALIPREKKISILE--------------------EP 140
Query: 203 RNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEE 262
A + ++ P NIEKSVKDLQRCTVSL RYRV++KEE
Sbjct: 141 SKALRGVTGP------------------------NIEKSVKDLQRCTVSLTRYRVMIKEE 176
Query: 263 MDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQ 322
+D+S+KK+K AFAEL +C++D+EV+L+AEMDKVK EAMEIL +RQKKAE LK++T +A Q
Sbjct: 177 VDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQ 236
Query: 323 MSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSHPKNSYSTRS 382
M+E QL ELRA+IKHFVSERKYDE+LG+ ARF+CD+E LK I G+++HPKN+YS+R+
Sbjct: 237 MAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRT 296
Query: 383 RCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IANSSGQPYQP 439
CSS+ + +A AA+S ++ +S + K P E AA + +S P
Sbjct: 297 PCSSLLPL-----LNAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMVSSLPSTADP 348
Query: 440 LREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-SRYQSAPSQA 495
+ +P N++ G Q R Q N+ +N G S G + G SR++ +
Sbjct: 349 SHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNSRHEH--RRQ 405
Query: 496 PGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQT 540
P N A + M+ P P S K P+R+ + T
Sbjct: 406 PHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADT 448
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 42.7 bits (99), Expect = 8e-04
Identities = 51/294 (17%), Positives = 122/294 (41%), Gaps = 13/294 (4%)
Query: 86 KKKNKKKKNKPK----PAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDT 141
+KK KK+K + K +E + + D ++ + E SEK V G D
Sbjct: 334 RKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDF 393
Query: 142 ESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQ 201
+DS +GL +++ + D S DT + + E +T ++Q
Sbjct: 394 SLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTS-----DSMEEGEITSDDEEKNKQ 448
Query: 202 PRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKE 261
+ ++ +T+ P SK S + ++ + +R +++ + +++
Sbjct: 449 NKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRR 508
Query: 262 EMDAS--IKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHV 319
+++ +K KQ + +S + ++++ +++E +R K+ +K+
Sbjct: 509 QINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEK 568
Query: 320 AVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSH 373
V +S+++ + R ++ +++Y+ED + + E K+ I S ++ H
Sbjct: 569 KVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCE--KEKISSSKELKH 620
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/326 (19%), Positives = 137/326 (42%), Gaps = 30/326 (9%)
Query: 30 ENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTGKKKN 89
EN++ I + NNEI ++ +T Q + S +L E + +K+
Sbjct: 698 ENLRRNIERI--------NNEIDQLMNQMQQI--ETQQRKFKASRDSILSEMKMLKEKRQ 747
Query: 90 KKKKN-KPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNG-AINDTESVDSL 147
+ +K PK + S S+ +S S K + ++ ++ D + VD+L
Sbjct: 748 QSEKTFMPKQRSL-------QSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDAL 800
Query: 148 SEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAK 207
++ + L + R+L + + + R + L + + + N +
Sbjct: 801 NDEIRQLQQENRQLLNERIKLEGIITRVETYLNENL---RKRLDQVEQELNELRETEGGT 857
Query: 208 SLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDA-- 265
L+ T+E + N ++D +A S+ L ++I+K+ ++ S+ R++ + KE MDA
Sbjct: 858 VLTATTSELEAINKRVKDT-MARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAIN 916
Query: 266 -SIKKMKQAFAELESCLMDREVAL--LAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQ 322
K++++ L +E + + E+ + EA E + K +L +K+ +
Sbjct: 917 HDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLK-QLFRKLEQCNTE 975
Query: 323 MSEQQLVELRADIKHFVSERKYDEDL 348
+ + V +A + FV+ + E L
Sbjct: 976 LKKYSHVNKKA-LDQFVNFSEQKEKL 1000
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/295 (23%), Positives = 115/295 (38%), Gaps = 30/295 (10%)
Query: 55 LQHFDNCVDKTVQAFMEGSASEVLK-EWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKSV 113
+Q F++ D T + SAS+VLK E T T K +K + KPK A K
Sbjct: 94 IQVFEDGADTTSPETPDSSASKVLKREGTDTTAKTSKLRGLKPKKAPTARKTTTRRPKPT 153
Query: 114 SIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAM-LDTL 172
A +S G +G G ++ +E L I L P + L +
Sbjct: 154 RPASTGVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSP 213
Query: 173 DRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSK 232
+ L+ V D E K T+ L R + + + + L +
Sbjct: 214 SKEEEGLRAQVRDLEEKLETLR--------------LKRAEDKAKLKELEKHKIQLEQVQ 259
Query: 233 KLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDAS---IKKMKQAFAELESCLMDREVA-- 287
+ S +++ DLQR L R KE ++A +++M +E +D+E+A
Sbjct: 260 EWKSKMQEQQADLQR---RLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEE 316
Query: 288 ----LLAEMDKVKAEAMEILLSRQ-KKAELLKKMTHVAVQMSE-QQLVELRADIK 336
L E++ +K E+ + KAE+ +K + A + +QL E A +K
Sbjct: 317 RAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLK 371
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/192 (22%), Positives = 80/192 (41%), Gaps = 21/192 (10%)
Query: 142 ESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQ 201
+S +L + +E + ELED A D R LQ + FE + L + ++
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE-RDLQGRDEQSEEK 1583
Query: 202 PRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKE 261
+ + + E + + +A KKL E +KDL+ S + R
Sbjct: 1584 KKQLVRQVREMEAELE-DERKQRSMAVAARKKL----EMDLKDLEAHIDSANKNR----- 1633
Query: 262 EMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAV 321
D +IK++++ A+++ C+ E+D +A EIL ++ + LK M +
Sbjct: 1634 --DEAIKQLRKLQAQMKDCMR--------ELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 322 QMSEQQLVELRA 333
Q+ E+ RA
Sbjct: 1684 QLQEELAAAERA 1695
Score = 35.0 bits (79), Expect = 0.18
Identities = 45/233 (19%), Positives = 95/233 (40%), Gaps = 29/233 (12%)
Query: 141 TESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHS----- 195
++S+ L E + D E E L++T L+ +D + + +
Sbjct: 1015 SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074
Query: 196 -IHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLAR 254
+ +++ +L+R E NM ++ + ++L S I + +DL+ S
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKI-----RELESQISELQEDLESERAS--- 1126
Query: 255 YRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLK 314
+ + K+ + ELE+ + E L D A+ E+ R+++ +LK
Sbjct: 1127 --------RNKAEKQKRDLGEELEALKTELEDTL----DSTAAQ-QELRSKREQEVNILK 1173
Query: 315 KMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDS 367
K + E Q+ E+R KH + + E L + R ++E K+++++
Sbjct: 1174 KTLEEEAKTHEAQIQEMRQ--KHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Score = 31.6 bits (70), Expect = 1.9
Identities = 48/221 (21%), Positives = 97/221 (43%), Gaps = 40/221 (18%)
Query: 151 LETLSIDAR--ELEDPESAMLDT---LDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNA 205
LE ++ +A+ +LE+ + + D L + +L++ +++F T N +
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT---------NLTEEEEK 1014
Query: 206 AKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDA 265
+KSL++ + + +E+ L +K +EK+ + L+ + L+
Sbjct: 1015 SKSLAKLKNKHEAMITDLEE-RLRREEKQRQELEKTRRKLEGDSTDLSD----------- 1062
Query: 266 SIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSE 325
I +++ AEL+ L +E L A + +V+ EA + K LKK+ + Q+SE
Sbjct: 1063 QIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ-------KNMALKKIRELESQISE 1115
Query: 326 QQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSID 366
Q +L ++ K DLG ++E LK ++
Sbjct: 1116 LQ-EDLESERASRNKAEKQKRDLGE------ELEALKTELE 1149
Score = 29.3 bits (64), Expect = 9.7
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 26/156 (16%)
Query: 229 ATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEE----MDASIKKMKQAFAELESCLMDR 284
A +++L + + ++L+ L RV +EE + A KKM+Q ELE L +
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEA-RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE 955
Query: 285 EVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKHFVSERKY 344
E S ++K +L K T ++ E++ + L E+K
Sbjct: 956 E-------------------SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL 996
Query: 345 DEDLGRVARFTCDVETLKKSIDSFGQVSHPKNSYST 380
ED R+A FT ++ ++ S ++ + + T
Sbjct: 997 LED--RIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 40.4 bits (93), Expect = 0.004
Identities = 45/161 (27%), Positives = 68/161 (42%), Gaps = 26/161 (16%)
Query: 376 NSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIANSSGQ 435
+S S+ S SS +S S SS S +S++SSS+ +S S +S++ PG P A+ +
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG--PQALPKPASP 2665
Query: 436 PYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRYQSAPSQA 495
P PG RR +P DS+ R+ S YS R + +P +
Sbjct: 2666 KKPP-----PGERRSRSPRKP-------------IDSLRDSRSLS-YSPVERRRPSPQPS 2706
Query: 496 PGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPR 536
P R Q S+ G+ +PS K+ PR
Sbjct: 2707 P-----RDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
Score = 39.7 bits (91), Expect = 0.007
Identities = 37/155 (23%), Positives = 60/155 (38%), Gaps = 4/155 (2%)
Query: 381 RSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIANSSGQPYQPL 440
RS SS +S S SS S +S++SSS+ S S + + P + + + P + +
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 441 REVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRYQSAPSQAPGNTI 500
RE P + R +S+ + S +SS SS S S+ S + ++
Sbjct: 2591 REGRPPEPTPAKRKR----RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 501 ERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKP 535
G P P P ++ RKP
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Score = 34.3 bits (77), Expect = 0.30
Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 14/161 (8%)
Query: 379 STRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIANSSGQPYQ 438
ST ++ S + + S++SSS+ +S S +S++ + + + ++ + S P Q
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571
Query: 439 P---LREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRYQSAPSQA 495
P L+ V + R P + R S SS SS S S+ S +
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS------SSSSSSSSSSSSSSSSS 2625
Query: 496 PGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPR 536
++ + S+ ++ + S PSP P PQ P+
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPG-----PQALPK 2661
Score = 32.7 bits (73), Expect = 0.87
Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 9/149 (6%)
Query: 394 SPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIANSSGQPYQPLREVLPGNRRGGQG 453
SP ++ + S C + A ++ + G A +S+G L PG G
Sbjct: 2449 SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV-ATTTSSAGDHNGMLSVPAPGVPHSDVG 2507
Query: 454 YRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRYQSAPSQAPGNTIERGQTHSAGTNGT 513
P + P R+SS SS S S+ S + ++ G + S+ + G+
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS-SSDSEGS 2566
Query: 514 GVSMEPS-------PPTPSFKKGLPQRKP 535
+ ++P PTP+ K+ + + +P
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
Score = 32.0 bits (71), Expect = 1.5
Identities = 41/171 (23%), Positives = 60/171 (35%), Gaps = 15/171 (8%)
Query: 374 PKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIANSS 433
P + Y + + S + SPS SST PP+ T + P A S
Sbjct: 331 PSSPYEDKDKDKKEKSATRPSPSPER---SSTGPEPPAPTPLLAERHGGSPQPLATTPLS 387
Query: 434 GQPYQPLREVLPGNRRG---GQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRYQS 490
+P P E P R PQ S + + R+ +SS S
Sbjct: 388 QEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES------P 441
Query: 491 APSQAPGN--TIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPRTSQ 539
P+ APG+ I T ++G + TPS + G R P T++
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG-RSRSPATAK 491
Score = 30.4 bits (67), Expect = 4.3
Identities = 42/175 (24%), Positives = 59/175 (33%), Gaps = 10/175 (5%)
Query: 372 SHPKNSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIAN 431
S K R R S +S + S S S S + +SP +K AP + +
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV---KDKPRAAPRAQSGS--D 1619
Query: 432 SSGQPYQPLREVLP-----GNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGS 486
SS +P P LP G+ G+G P+G S + + S R S
Sbjct: 1620 SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK 1679
Query: 487 RYQSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKGLPQRKPRTSQTE 541
P + + T A + S SP T S +R P S E
Sbjct: 1680 TKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE 1734
Score = 30.0 bits (66), Expect = 5.7
Identities = 43/170 (25%), Positives = 57/170 (33%), Gaps = 18/170 (10%)
Query: 381 RSRCSSVTSVSLSSPSDA---------SAASSSTCASPPSLT------SANKKNFAPGET 425
+SR SS S SLSSP S + SS C S T S + + A T
Sbjct: 751 KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 426 PAAIANSSGQPYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG 485
P + SS P + P + KS P QG S S
Sbjct: 811 PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Query: 486 SRYQSAPSQAPGNTIERGQTHS-AGTNGTGVSMEPSPPTPSFKKGLPQRK 534
S ++S+P P HS +G++ V P + PQ K
Sbjct: 871 SCFESSPD--PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPK 918
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 39.7 bits (91), Expect = 0.007
Identities = 35/159 (22%), Positives = 75/159 (47%), Gaps = 12/159 (7%)
Query: 210 SRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKK 269
S+P TE G D+ A +++L + + + + Q+C +SL + + +K+E++ S+ K
Sbjct: 60 SKPVTE------GTGDIIKALTERLDALLLEKAETEQQC-LSLKKENIKMKQEVEDSVTK 112
Query: 270 MKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLV 329
M A ELE + + E++ +K E M + + L+K A+ +
Sbjct: 113 MGDAHKELE----QSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSE 168
Query: 330 ELRADIKHFVSERKYDEDLGRV-ARFTCDVETLKKSIDS 367
+L+ + +K E++ ++ F + L+K +D+
Sbjct: 169 QLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDA 207
Score = 35.4 bits (80), Expect = 0.13
Identities = 59/307 (19%), Positives = 124/307 (40%), Gaps = 32/307 (10%)
Query: 32 MKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTGKKKNKK 91
M E+ + + ++ N+ ++ + Q + + + + +V+ G+ K
Sbjct: 734 MVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKI 793
Query: 92 KKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSL-SEG 150
+ K A + + + K + +E+S E+ + + D E L +
Sbjct: 794 NEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEE-------LKSLLRDYEQEKVLLRKE 846
Query: 151 LETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHS--IHNSQQ------- 201
LE + + L+ M + ++T QN + E S T IHN ++
Sbjct: 847 LEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEH 906
Query: 202 ----PRNAAKSLSRPTTE------TQFSNMGMEDVPLATSKKLSS---NIEKSVKDLQRC 248
P K L E + + +++ PL++ K+L N+EK K+ +
Sbjct: 907 ENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEK 966
Query: 249 TVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVK-AEAME-ILLSR 306
+ V K+E+D+S K+ + ELES +++ + D ++ AE+ + +LL
Sbjct: 967 INKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEY 1026
Query: 307 QKKAELL 313
+K++E L
Sbjct: 1027 EKQSEQL 1033
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 39.7 bits (91), Expect = 0.007
Identities = 41/137 (29%), Positives = 57/137 (41%), Gaps = 27/137 (19%)
Query: 76 EVLKEWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVN 135
E+ KEWT GK K++N K S DSS S S E +S S + G +G
Sbjct: 655 ELAKEWTPAGK---AKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESG--EE 709
Query: 136 GAINDTESVDSLSE---------GLETLSIDAR-------------ELEDPESAMLDTLD 173
G N+ S DS SE GLE R E E+ +S D+ +
Sbjct: 710 GDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSN 769
Query: 174 RTGSMLQNGVSDFETKS 190
S +++ SD E++S
Sbjct: 770 DESSSIEDSSSDSESES 786
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 39.7 bits (91), Expect = 0.007
Identities = 57/236 (24%), Positives = 93/236 (39%), Gaps = 17/236 (7%)
Query: 141 TESVDSLSEGLETLSIDARELED-PESAMLDTLDRTGSM-----LQNGVSDFETKSLTMH 194
+ +D L E +L EL+D E G M L+ V D E K +
Sbjct: 331 SRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEEL- 389
Query: 195 SIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVP--LATSKKLSSNIEKSVKDLQRCTVSL 252
I +Q R+ K L R T +++ + +E + + +KL KS ++ +L
Sbjct: 390 -IKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNL 448
Query: 253 ARYRVVVKEEMDASIKKMKQAFAELE---SCLMDREVALLAEMDKVKAEAMEILLSRQKK 309
+ R+ K+ + ++ +K ELE S L E L ++ K+K + + R+
Sbjct: 449 EKERMTTKQ-LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTM 507
Query: 310 AELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSI 365
+E LKK S Q VE K K E+ R + DVE S+
Sbjct: 508 SEKLKKTEDKLQAASSQLQVEQN---KVTTVTEKLIEETKRALKSKTDVEEKMYSV 560
>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
sapiens]
Length = 893
Score = 39.7 bits (91), Expect = 0.007
Identities = 57/236 (24%), Positives = 93/236 (39%), Gaps = 17/236 (7%)
Query: 141 TESVDSLSEGLETLSIDARELED-PESAMLDTLDRTGSM-----LQNGVSDFETKSLTMH 194
+ +D L E +L EL+D E G M L+ V D E K +
Sbjct: 91 SRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEEL- 149
Query: 195 SIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVP--LATSKKLSSNIEKSVKDLQRCTVSL 252
I +Q R+ K L R T +++ + +E + + +KL KS ++ +L
Sbjct: 150 -IKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNL 208
Query: 253 ARYRVVVKEEMDASIKKMKQAFAELE---SCLMDREVALLAEMDKVKAEAMEILLSRQKK 309
+ R+ K+ + ++ +K ELE S L E L ++ K+K + + R+
Sbjct: 209 EKERMTTKQ-LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTM 267
Query: 310 AELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSI 365
+E LKK S Q VE K K E+ R + DVE S+
Sbjct: 268 SEKLKKTEDKLQAASSQLQVEQN---KVTTVTEKLIEETKRALKSKTDVEEKMYSV 320
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 39.7 bits (91), Expect = 0.007
Identities = 57/236 (24%), Positives = 93/236 (39%), Gaps = 17/236 (7%)
Query: 141 TESVDSLSEGLETLSIDARELED-PESAMLDTLDRTGSM-----LQNGVSDFETKSLTMH 194
+ +D L E +L EL+D E G M L+ V D E K +
Sbjct: 331 SRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEEL- 389
Query: 195 SIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVP--LATSKKLSSNIEKSVKDLQRCTVSL 252
I +Q R+ K L R T +++ + +E + + +KL KS ++ +L
Sbjct: 390 -IKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNL 448
Query: 253 ARYRVVVKEEMDASIKKMKQAFAELE---SCLMDREVALLAEMDKVKAEAMEILLSRQKK 309
+ R+ K+ + ++ +K ELE S L E L ++ K+K + + R+
Sbjct: 449 EKERMTTKQ-LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTM 507
Query: 310 AELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSI 365
+E LKK S Q VE K K E+ R + DVE S+
Sbjct: 508 SEKLKKTEDKLQAASSQLQVEQN---KVTTVTEKLIEETKRALKSKTDVEEKMYSV 560
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 39.3 bits (90), Expect = 0.009
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 39/245 (15%)
Query: 147 LSEGLETLSIDARELEDP----ESAMLDTLDRTGSMLQNGVSDFETK-------SLTMHS 195
L E LE + + + E E +LD DR + S TK +
Sbjct: 1685 LLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAE 1744
Query: 196 IHNS-QQPRNAAKSLSRPTTETQF--SNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSL 252
+ NS Q+ RNA + + T+ + E A +++ N+E++VKDLQ
Sbjct: 1745 VENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ------ 1798
Query: 253 ARYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAEL 312
+R+ E++ ++K K+ +LE+ + + E E+D + E L K
Sbjct: 1799 --HRLDEAEQL--ALKGGKKQIQKLENRVRELE----NELDVEQKRGAEALKGAHKYERK 1850
Query: 313 LKKMTHVAVQ-----MSEQQLVE-LRADIKHF-----VSERKYDEDLGRVARFTCDVETL 361
+K+MT+ A + + Q LV+ L+A +K + +E + + L R R ++E
Sbjct: 1851 VKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEA 1910
Query: 362 KKSID 366
+ D
Sbjct: 1911 AERAD 1915
Score = 33.1 bits (74), Expect = 0.67
Identities = 58/250 (23%), Positives = 105/250 (42%), Gaps = 47/250 (18%)
Query: 89 NKKKKNKPKPAAEPSNGIPDSSKSV-SIQEEQSAPSSEKGGM-NGYHVNGAINDTESVDS 146
+KK++N K AE + +S + + Q+E + S+E M N Y E VD
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYE--------EVVDQ 1498
Query: 147 LSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAA 206
L ETL + + L++ S + + + TG N Q+
Sbjct: 1499 L----ETLRRENKNLQEEISDLTEQIAETGK--------------------NLQEAEKTK 1534
Query: 207 KSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDAS 266
K + + ++ Q + +E+V + + S I + +L + L R +V+ K+E
Sbjct: 1535 KLVEQEKSDLQ---VALEEVE-GSLEHEESKILRVQLELSQVKSELDR-KVIEKDEEIEQ 1589
Query: 267 IKKMKQAFAELESCLMDREVALLAEMDKVKAE------AMEILL--SRQKKAELLKKMTH 318
+K+ Q AE ++D E+ + ++K + MEI L S ++ AE K +
Sbjct: 1590 LKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRT 1649
Query: 319 VAVQMSEQQL 328
V Q+ + QL
Sbjct: 1650 VQGQLKDSQL 1659
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 38.9 bits (89), Expect = 0.012
Identities = 44/204 (21%), Positives = 90/204 (44%), Gaps = 15/204 (7%)
Query: 139 NDTESVDSLSEGLETLSIDARELEDPESAM-LDTLDRTGSMLQNGVSDFETKSLTMHSIH 197
N+ E +L+ L+ +D + D E+ + L+T + +L+N + T H
Sbjct: 857 NEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKE----LLKNAQKEIATLKQ-----H 907
Query: 198 NSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRV 257
S A S+ T + Q SN D ++ ++ + + L+ T ++ +Y+
Sbjct: 908 LSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQA 967
Query: 258 VVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMT 317
+V ++ S+ K KQ E+ + R L E + + + + L+ +K+ + L+
Sbjct: 968 MVTS-LEESLNKEKQVTEEVRKNIEVR----LKESAEFQTQLEKKLMEVEKEKQELQDDK 1022
Query: 318 HVAVQMSEQQLVELRADIKHFVSE 341
A++ EQQL EL+ + +E
Sbjct: 1023 RRAIESMEQQLSELKKTLSSVQNE 1046
Score = 32.3 bits (72), Expect = 1.1
Identities = 36/190 (18%), Positives = 77/190 (40%), Gaps = 10/190 (5%)
Query: 149 EGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKS 208
E L+ D R S LD + MLQ+ V + + + S+H Q A
Sbjct: 698 EKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRRE---ITSLHERNQKLTATTQ 754
Query: 209 LSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEE---MDA 265
T ++ + LA ++ + N++K + L+ V L++ R + E +
Sbjct: 755 KQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL 814
Query: 266 SIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSE 325
+ ++ LE + + L ++++K++ E + +KK E + H + +
Sbjct: 815 LLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHL----KKKLENEVEQRHTLTRNLD 870
Query: 326 QQLVELRADI 335
QL++ + +
Sbjct: 871 VQLLDTKRQL 880
>gi|33356179 transcription termination factor, RNA polymerase I
[Homo sapiens]
Length = 905
Score = 38.1 bits (87), Expect = 0.021
Identities = 44/197 (22%), Positives = 79/197 (40%), Gaps = 21/197 (10%)
Query: 86 KKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTESVD 145
K K+KKKK K + +P+S +S E S SE G + G ++ S
Sbjct: 329 KNKSKKKKKKSNHQEFEAVAMPESLESA--YPEGSQVGSEVGTVEGSTALKGFKESNSTK 386
Query: 146 SLSEGLETLSIDAREL---------EDPESAMLDTLDRTGSMLQNGVSDFETKSLT---M 193
S+ + S+ + ++ ES + D+++ G+M++ GV + T +
Sbjct: 387 KKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACL 446
Query: 194 HSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLA 253
S H + PR P E + + ED + S + + S DL L
Sbjct: 447 ASKHVQEAPR------LEPANE-EHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQ 499
Query: 254 RYRVVVKEEMDASIKKM 270
+ +K+ ++IK+M
Sbjct: 500 EFIPNIKDRATSTIKRM 516
>gi|239752579 PREDICTED: hypothetical protein XP_002348295 [Homo
sapiens]
Length = 240
Score = 38.1 bits (87), Expect = 0.021
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 397 DASAASSSTCASPPSLT-SANKKNFAPGETPAAIANSSGQPYQPLRE---VLPGNRRGGQ 452
DAS + S C S P S KK GE AA+ SG+ +P R+ V+ RGG+
Sbjct: 129 DASRSGSRVCRSRPQTRGSGGKKLRQRGEKAAAVKTCSGRSKKPGRQKAAVMGAKSRGGR 188
Query: 453 GYRPQ 457
G +PQ
Sbjct: 189 GKKPQ 193
>gi|239746945 PREDICTED: SAGE1-like protein-like [Homo sapiens]
Length = 990
Score = 37.7 bits (86), Expect = 0.027
Identities = 60/249 (24%), Positives = 112/249 (44%), Gaps = 42/249 (16%)
Query: 106 IPDSSKSVSIQEEQSAPSSEKGGM--NGYHVNGA----INDTESVDSLSEGLETLSIDAR 159
IPD++ +IQEE+ E G M +G+ N A IN TE L+ L++ S D
Sbjct: 426 IPDATVIHNIQEEEM----ENGQMPPDGFLSNSAPLELINMTEDCMPLN-ALDSFSYD-- 478
Query: 160 ELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFS 219
+L R + ++ ++F + +S+ P A S+ P
Sbjct: 479 ---------FTSLSREELLYKHDSNEFAVGTKN-YSVSAGDPPVTAMSSVETP------- 521
Query: 220 NMGMEDVPLATSKKLSSNIE-KSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAE-- 276
+ A +KK++ +I+ + +K++QR + R +++ EE+ S+K +K+ F E
Sbjct: 522 -----QISPAMAKKINQDIKCQLMKEVQRFGQNYKRIFILL-EELQGSMK-VKRQFVEFT 574
Query: 277 LESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIK 336
+ + ++VAL+ +++KV E +K + ++K V VQ + A I
Sbjct: 575 IREAVRFKKVALIQQLEKVLKEIDS--HCHLRKVKHMRKKIIVLVQRPRRNKGTRDATIT 632
Query: 337 HFVSERKYD 345
H V E + +
Sbjct: 633 HNVGEERME 641
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 37.7 bits (86), Expect = 0.027
Identities = 35/148 (23%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 229 ATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVAL 288
A +KL + KD+ ++LA+ V++E A+ K+K E+ +D +A
Sbjct: 942 AKKRKLEDECSELKKDIDDLELTLAK----VEKEKHATENKVKNLTEEMAG--LDETIAK 995
Query: 289 LAEMDKVKAEA-MEILLSRQKKAELLKKMTHVAVQMSEQ---------QLVELRADIKHF 338
L + K EA + L Q + + + +T +++ +Q Q ++R D++
Sbjct: 996 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLER- 1054
Query: 339 VSERKYDEDLGRVARFTCDVETLKKSID 366
++RK + DL T D+E K+ +D
Sbjct: 1055 -AKRKLEGDLKLAQESTMDIENDKQQLD 1081
Score = 33.1 bits (74), Expect = 0.67
Identities = 48/212 (22%), Positives = 90/212 (42%), Gaps = 24/212 (11%)
Query: 153 TLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQ--------QPRN 204
TL R + E +LD +R + S TK I Q + RN
Sbjct: 1695 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARN 1754
Query: 205 AAKSLSRPTTETQF--SNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEE 262
A + + T+ + E A +++ N+E++VKDLQ +R+ E+
Sbjct: 1755 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ--------HRLDEAEQ 1806
Query: 263 MDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQ 322
+ ++K K+ +LE+ + + E + +E K EA++ L ++K + L T +
Sbjct: 1807 L--ALKGGKKQIQKLEARVRELEGEVESE-QKRNVEAVKGLRKHERKVKELTYQTEEDRK 1863
Query: 323 --MSEQQLVE-LRADIKHFVSERKYDEDLGRV 351
+ Q LV+ L+A +K + + + E+ V
Sbjct: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQSNV 1895
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 37.4 bits (85), Expect = 0.035
Identities = 53/250 (21%), Positives = 109/250 (43%), Gaps = 18/250 (7%)
Query: 115 IQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAMLDTLDR 174
I+ EQ+ ++E+ G + I+ ++ + +G E L R+L + +S + T R
Sbjct: 457 IEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKG-EVLRYK-RKLREAQSDLNKTRLR 514
Query: 175 TGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKL 234
+GS L + S +++ P++ L +P +E S + ++
Sbjct: 515 SGSAL-------------LQSQSSTEDPKDEPAEL-KPDSEDLSSQSSASKASQEDANEI 560
Query: 235 SSNIEKSVKDLQRCTVSLARYRVVVKE-EMDASIKKMKQAFAELESCLMDREVALLAEMD 293
S ++ ++ +R R R KE E + +K+K++ E +S D+E +
Sbjct: 561 KSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSA-KDKEKGKHDDGR 619
Query: 294 KVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVAR 353
K +AE ++ L KKA+ +K + + M E R ++ +E+K +L + +
Sbjct: 620 KKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQ 679
Query: 354 FTCDVETLKK 363
D+E +K
Sbjct: 680 RLKDLEDKEK 689
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 37.0 bits (84), Expect = 0.046
Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 231 SKKLSSNIEKSVKDLQRCTV-SLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVA-- 287
+KKLS+ E S +D+ R T+ +L+R E+DA +K + A L++ E
Sbjct: 1140 NKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGV 1199
Query: 288 -------LLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVELRADI 335
LL E DK+K + ++ +Q+ ++ M H + Q+ E +L +L+A +
Sbjct: 1200 NSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQE-ELHQLQAQV 1253
Score = 33.5 bits (75), Expect = 0.51
Identities = 33/151 (21%), Positives = 61/151 (40%), Gaps = 4/151 (2%)
Query: 151 LETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLS 210
L L + ++LED ++D L++ S N E L H N ++ L
Sbjct: 571 LNDLHLTKQKLEDKVENLVDQLNK--SQESNVSIQKENLELKEHIRQNEEELSRIRNELM 628
Query: 211 RPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKM 270
+ Q SN +D L + N+++++ +L++ +L + VK E + +
Sbjct: 629 QSLN--QDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLAC 686
Query: 271 KQAFAELESCLMDREVALLAEMDKVKAEAME 301
+ +LE CL L + V+ ME
Sbjct: 687 EDVRHQLEECLAGNNQLSLEKNTIVETLKME 717
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 36.6 bits (83), Expect = 0.061
Identities = 70/347 (20%), Positives = 142/347 (40%), Gaps = 38/347 (10%)
Query: 47 SNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKNKPKPAAEPSNGI 106
S E++ +L++ D V + Q + SA +L++ T++ + P P EP
Sbjct: 5172 SKAELLTLLEYHDTFVLELEQ---QQSALGMLRQQTLSMLQDGAA----PTPGEEPP--- 5221
Query: 107 PDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLE-------------T 153
+ ++ +++ EK NG V + D E V++ ++ T
Sbjct: 5222 --LMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPT 5279
Query: 154 LSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPT 213
+ IDA +LE+ + + + + + ++ + + K L +++I S+ A+
Sbjct: 5280 IEIDA-QLEELQILLTEATNHRQN-IEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLK 5337
Query: 214 TETQFSNMGME-DVPLATSKKLSSNIEKSVKDLQRCTVSL-ARYRVVVKEEMDASIKKMK 271
Q + E + ATS++LS I+K KDL L A+ VV+ + D K
Sbjct: 5338 IRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTD-----QK 5392
Query: 272 QAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVEL 331
EL+ C + + L A + K + ++ KK L ++ ++ +E +L +L
Sbjct: 5393 VLGEELDGC-NSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKL 5451
Query: 332 RADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSHPKNSY 378
H +Y+E L + ++ + L ++ S + Y
Sbjct: 5452 NQAASHL---EEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQY 5495
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 36.6 bits (83), Expect = 0.061
Identities = 70/347 (20%), Positives = 142/347 (40%), Gaps = 38/347 (10%)
Query: 47 SNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKNKPKPAAEPSNGI 106
S E++ +L++ D V + Q + SA +L++ T++ + P P EP
Sbjct: 5243 SKAELLTLLEYHDTFVLELEQ---QQSALGMLRQQTLSMLQDGAA----PTPGEEPP--- 5292
Query: 107 PDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLE-------------T 153
+ ++ +++ EK NG V + D E V++ ++ T
Sbjct: 5293 --LMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPT 5350
Query: 154 LSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPT 213
+ IDA +LE+ + + + + + ++ + + K L +++I S+ A+
Sbjct: 5351 IEIDA-QLEELQILLTEATNHRQN-IEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLK 5408
Query: 214 TETQFSNMGME-DVPLATSKKLSSNIEKSVKDLQRCTVSL-ARYRVVVKEEMDASIKKMK 271
Q + E + ATS++LS I+K KDL L A+ VV+ + D K
Sbjct: 5409 IRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTD-----QK 5463
Query: 272 QAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVEL 331
EL+ C + + L A + K + ++ KK L ++ ++ +E +L +L
Sbjct: 5464 VLGEELDGC-NSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKL 5522
Query: 332 RADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSHPKNSY 378
H +Y+E L + ++ + L ++ S + Y
Sbjct: 5523 NQAASHL---EEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQY 5566
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 36.6 bits (83), Expect = 0.061
Identities = 44/177 (24%), Positives = 65/177 (36%), Gaps = 13/177 (7%)
Query: 372 SHPKNSYSTRSR--CSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGET-PAA 428
S KNS + + S +T LSS S ++ S S +K N +P + P
Sbjct: 1141 SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200
Query: 429 IANSSGQPYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRY 488
++ P +P+ PG + P S G S G +S SSGS
Sbjct: 1201 GSDKLASPMKPV----PGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256
Query: 489 QSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPTPSFKKG-LPQRKPRTSQTEAVN 544
Q P + T S+ + +G SM S KG P R + S T ++
Sbjct: 1257 QKTPPSSNSCT-----ASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVID 1308
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 36.6 bits (83), Expect = 0.061
Identities = 54/258 (20%), Positives = 107/258 (41%), Gaps = 33/258 (12%)
Query: 112 SVSIQEEQSAPSSEKGGMNGYHVNGAINDTE-SVDSLSEGLETLSIDARELEDPESAML- 169
+VS++EE ++ + + Y + D + S S+ +TL+ + + LE+ A+L
Sbjct: 354 TVSLEEELKKANAARTQLETY--KRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLK 411
Query: 170 ---------DTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSN 220
DTL T L+ S + L ++ N A + F
Sbjct: 412 EKERLIEQRDTLKETNEELR--CSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIR 469
Query: 221 MGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESC 280
+ E+ L ++ S N + +++LQ R E++ + K+ EL+
Sbjct: 470 LQHENKMLRLQQEGSEN--ERIEELQEQLEQKHR----KMNELETEQRLSKERIRELQQQ 523
Query: 281 LMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMT--HVAVQMSEQQLVELRADIKHF 338
+ D + +L + K + E+ L +QK ++K+T H +Q ++ + +L+ DI
Sbjct: 524 IEDLQKSLQEQGSKSEGESSSKL--KQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQN 581
Query: 339 VSE--------RKYDEDL 348
V + +K DED+
Sbjct: 582 VQKINELEAALQKKDEDM 599
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 36.6 bits (83), Expect = 0.061
Identities = 41/204 (20%), Positives = 87/204 (42%), Gaps = 15/204 (7%)
Query: 158 ARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQ 217
A+ + + A LD L L+N + +F+ K + Q + L R E +
Sbjct: 428 AKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE--NELRRSMEEMK 485
Query: 218 FSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAEL 277
N ++ ++++ ++E +K++++C + EEM A + +L
Sbjct: 486 KENNLLKSHSEQKAREVC-HLEAELKNIKQCLNQSQNFA----EEMKAKNTSQETMLRDL 540
Query: 278 ESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKH 337
+ + +E +L E K+K ++ R +LLKK H Q+++ +L + + K
Sbjct: 541 QEKINQQENSLTLE--KLKLAVADLEKQRDCSQDLLKKREHHIEQLND-KLSKTEKESKA 597
Query: 338 FVS-----ERKYDEDLGRVARFTC 356
+S +++Y+E F+C
Sbjct: 598 LLSALELKKKEYEELKEEKTLFSC 621
Score = 33.1 bits (74), Expect = 0.67
Identities = 102/496 (20%), Positives = 183/496 (36%), Gaps = 97/496 (19%)
Query: 109 SSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAM 168
+ K+ +QEE S + G + E + S + L+ L+++ EL+ M
Sbjct: 2629 AQKTAELQEELSGEKNRLAGELQLLL-------EEIKSSKDQLKELTLENSELKKSLDCM 2681
Query: 169 -LDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMEDVP 227
D +++ G + + +++++ + +H +++ A + E + +
Sbjct: 2682 HKDQVEKEGKVREE-IAEYQLR------LHEAEKKHQALLLDTNKQYEVEIQTYREK--- 2731
Query: 228 LATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDR--- 284
TSK+ + +K DL + + KEE++ S+K Q EL+ MD
Sbjct: 2732 -LTSKEECLSSQKLEIDLLKSS----------KEELNNSLKATTQILEELKKTKMDNLKY 2780
Query: 285 -------------EVALLAEMDKVKAEAMEILLSR--QKKAELLKKMTHVAVQMSEQQLV 329
++ LL + K E EIL Q +A K+ T + +L
Sbjct: 2781 VNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELT 2840
Query: 330 ELRADIKHFVSE--RKYDEDLGRVARFTCDVETLKKSIDSF-GQVSHPKNSYSTR----- 381
++K + E ++ DE L + E L+K+ + QV+H + S +
Sbjct: 2841 TEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGS 2900
Query: 382 ----------SRCSSVTSVSLSSPSDASAAS------------SSTCASPPSLTSANKKN 419
S SVT LSS + ++ T A+P S + +KK
Sbjct: 2901 PLLGPVVPGPSPIPSVTEKRLSSGQNKASGKRQRSSGIWENGRGPTPATPESFSKKSKKA 2960
Query: 420 FAPGETPAAIANSSGQPYQPLREVLPGNRRGGQGYRPQGQKSNDPMNQGRHDSMGRYRNS 479
G PA ++ G ++P E LP + G P G+ S + R +M R S
Sbjct: 2961 VMSGIHPA--EDTEGTEFEP--EGLPEVVKKGFADIPTGKTSPYIL---RRTTMAT-RTS 3012
Query: 480 SWYSSGSRYQSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPT--------PSFK---- 527
++ S S N E + + G+ V + P P+ K
Sbjct: 3013 PRLAAQKLALSPLSLGKENLAESSKPTAGGSRSQKVKVAQRSPVDSGTILREPTTKSVPV 3072
Query: 528 KGLPQRKPRTSQTEAV 543
LP+R P S E +
Sbjct: 3073 NNLPERSPTDSPREGL 3088
>gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens]
Length = 278
Score = 36.2 bits (82), Expect = 0.079
Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 27/173 (15%)
Query: 62 VDKTVQAFMEGSASEVLK---------EWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKS 112
V KT E +A+E+++ E T K KKKK KP+ A + NGI D S S
Sbjct: 81 VMKTEMVQAEKTAAEIIRKLEKQETPEECAKTSVKPKKKKKQKPQEAPQ-ENGIKDPSNS 139
Query: 113 VSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAMLDTL 172
S ++ + S EK V+ +T SL +T S + DP+ A
Sbjct: 140 FSKPNKRKSFSKEK------LVSSHREETAGSISL-PNRKTSSPKEEAVNDPKEAG---- 188
Query: 173 DRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMED 225
+R+ + + G S + K L S P AA S S + + + ED
Sbjct: 189 NRSVTKKKTGNSPSKRKELV------SSGPEEAAGSKSSSKKKKKLHKVPQED 235
>gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens]
Length = 278
Score = 36.2 bits (82), Expect = 0.079
Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 27/173 (15%)
Query: 62 VDKTVQAFMEGSASEVLK---------EWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKS 112
V KT E +A+E+++ E T K KKKK KP+ A + NGI D S S
Sbjct: 81 VMKTEMVQAEKTAAEIIRKLEKQETPEECAKTSVKPKKKKKQKPQEAPQ-ENGIKDPSNS 139
Query: 113 VSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEGLETLSIDARELEDPESAMLDTL 172
S ++ + S EK V+ +T SL +T S + DP+ A
Sbjct: 140 FSKPNKRKSFSKEK------LVSSHREETAGSISL-PNRKTSSPKEEAVNDPKEAG---- 188
Query: 173 DRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMED 225
+R+ + + G S + K L S P AA S S + + + ED
Sbjct: 189 NRSVTKKKTGNSPSKRKELV------SSGPEEAAGSKSSSKKKKKLHKVPQED 235
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.122 0.333
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,538,955
Number of Sequences: 37866
Number of extensions: 1004501
Number of successful extensions: 6247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 5748
Number of HSP's gapped (non-prelim): 718
length of query: 545
length of database: 18,247,518
effective HSP length: 107
effective length of query: 438
effective length of database: 14,195,856
effective search space: 6217784928
effective search space used: 6217784928
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.