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Search of human proteins with 148727259
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148727259 solute carrier family 9 (sodium/hydrogen
exchanger), member 4 [Homo sapiens]
(798 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)... 1588 0.0
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),... 831 0.0
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens] 564 e-160
gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)... 464 e-130
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ... 462 e-130
gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens] 221 2e-57
gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),... 200 4e-51
gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ... 199 1e-50
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)... 189 1e-47
gi|14211919 solute carrier family 9, member 7 [Homo sapiens] 177 4e-44
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens] 58 4e-08
gi|224465231 solute carrier family 9, member 11 [Homo sapiens] 48 4e-05
gi|46409360 G protein-coupled receptor 148 [Homo sapiens] 32 1.8
gi|224451040 Yip1 interacting factor homolog B isoform 7 [Homo s... 31 5.2
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 31 5.2
gi|29366828 synaptotagmin XII [Homo sapiens] 31 5.2
gi|7657465 podocalyxin-like 2 [Homo sapiens] 31 5.2
gi|224451038 Yip1 interacting factor homolog B isoform 2 [Homo s... 30 6.8
gi|224451034 Yip1 interacting factor homolog B isoform 6 [Homo s... 30 6.8
gi|24308364 Yip1 interacting factor homolog B isoform 2 [Homo sa... 30 6.8
gi|89191845 Yip1 interacting factor homolog B isoform 3 [Homo sa... 30 6.8
gi|89191850 Yip1 interacting factor homolog B isoform 4 [Homo sa... 30 6.8
gi|89191848 Yip1 interacting factor homolog B isoform 5 [Homo sa... 30 6.8
>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
member 4 [Homo sapiens]
Length = 798
Score = 1588 bits (4113), Expect = 0.0
Identities = 798/798 (100%), Positives = 798/798 (100%)
Query: 1 MALQMFVTYSPWNCLLLLVALECSEASSDLNESANSTAQYASNAWFAAASSEPEEGISVF 60
MALQMFVTYSPWNCLLLLVALECSEASSDLNESANSTAQYASNAWFAAASSEPEEGISVF
Sbjct: 1 MALQMFVTYSPWNCLLLLVALECSEASSDLNESANSTAQYASNAWFAAASSEPEEGISVF 60
Query: 61 ELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIFGTDHK 120
ELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIFGTDHK
Sbjct: 61 ELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIFGTDHK 120
Query: 121 SPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLI 180
SPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLI
Sbjct: 121 SPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLI 180
Query: 181 CQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITV 240
CQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITV
Sbjct: 181 CQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITV 240
Query: 241 VLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQNISA 300
VLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQNISA
Sbjct: 241 VLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQNISA 300
Query: 301 IEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSS 360
IEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSS
Sbjct: 301 IEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSS 360
Query: 361 VSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKD 420
VSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKD
Sbjct: 361 VSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKD 420
Query: 421 QCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDV 480
QCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDV
Sbjct: 421 QCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDV 480
Query: 481 KKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLPK 540
KKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLPK
Sbjct: 481 KKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLPK 540
Query: 541 SSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQGIKRLSPEDVESIRDILTSNM 600
SSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQGIKRLSPEDVESIRDILTSNM
Sbjct: 541 SSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQGIKRLSPEDVESIRDILTSNM 600
Query: 601 YQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGHSLPWGKPAGTKNIRYLS 660
YQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGHSLPWGKPAGTKNIRYLS
Sbjct: 601 YQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGHSLPWGKPAGTKNIRYLS 660
Query: 661 YPYGNPQSAGRDTRAAGFSDDDSSDPGSPSITFSACSRIGSLQKQEAQEIIPMKSLHRGR 720
YPYGNPQSAGRDTRAAGFSDDDSSDPGSPSITFSACSRIGSLQKQEAQEIIPMKSLHRGR
Sbjct: 661 YPYGNPQSAGRDTRAAGFSDDDSSDPGSPSITFSACSRIGSLQKQEAQEIIPMKSLHRGR 720
Query: 721 KAFSFGYQRNTSQEEYLGGVRRVALRPKPLFHAVDEEGESGGESEGKASLVEVRSRWTAD 780
KAFSFGYQRNTSQEEYLGGVRRVALRPKPLFHAVDEEGESGGESEGKASLVEVRSRWTAD
Sbjct: 721 KAFSFGYQRNTSQEEYLGGVRRVALRPKPLFHAVDEEGESGGESEGKASLVEVRSRWTAD 780
Query: 781 HGHGRDHHRSHSPLLQKK 798
HGHGRDHHRSHSPLLQKK
Sbjct: 781 HGHGRDHHRSHSPLLQKK 798
>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
member 2 [Homo sapiens]
Length = 812
Score = 831 bits (2147), Expect = 0.0
Identities = 413/651 (63%), Positives = 512/651 (78%), Gaps = 9/651 (1%)
Query: 54 EEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGI 113
E + VF LDY +VQIP+E+TLWILLASLAKIGFHLYH+LP ++PESCLLI+VG L+GGI
Sbjct: 65 ESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGI 124
Query: 114 IFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGI 173
IFG D KSPP M + ++FLYLLPPIVL+ GYFMPTRPFFENIG+I W+AV+G L N++GI
Sbjct: 125 IFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGI 184
Query: 174 GLSLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEAL 233
G+SL+ ICQ++AFGL D+ LLQNLLFGSLISAVDPVAVLAVFE VNEQLY+++FGE+L
Sbjct: 185 GVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESL 244
Query: 234 LNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITR 293
LND +TVVLYN+ +F +M + IET+D+ AG A F VVG+GGVL GI GFI+AF TR
Sbjct: 245 LNDAVTVVLYNLFKSFCQM---KTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTR 301
Query: 294 FTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKY 353
FT NI IEPL VF++SYLSY+ AE +LSGI+AITACA+TM KYVEENVSQ SYTTIKY
Sbjct: 302 FTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKY 361
Query: 354 FMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRT 413
FMKMLSSVSETLIFIFMGVSTVGKNHEWNWAF+CFTLAFC +WRA+ VF L + N+FRT
Sbjct: 362 FMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRT 421
Query: 414 FPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGP 473
P + KDQ II Y G+RGA F+L FLLP ++FPRKK+F+TA +VVI+FTVFI GIT+ P
Sbjct: 422 IPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRP 481
Query: 474 LVRYLDVKKTNKK-ESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKI 532
LV +LDVK++NKK ++++EE++ RL DH+K GIEDVCGHW H RDKFKKFD +YLRK+
Sbjct: 482 LVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKL 541
Query: 533 LIRKNLPKSSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQGIKRLSPEDVESI 592
LIR+N PKSSIVSLYKKLE+K AIEM ETG++S+ R + I++++ + + I
Sbjct: 542 LIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPTFASLNDCREEKIRKVTSSETDEI 601
Query: 593 RDILTSNMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGHSLPWGKPAG 652
R++L+ N+YQ+RQRTLSYN+++L TSE+QAKEILIRR+++LRES+RK SL A
Sbjct: 602 RELLSRNLYQIRQRTLSYNRHSLTADTSERQAKEILIRRRHSLRESIRKDSSLNREHRAS 661
Query: 653 TKNIRYLSYPYGNP-----QSAGRDTRAAGFSDDDSSDPGSPSITFSACSR 698
T RYLS P Q + A G S D +D G+ + +R
Sbjct: 662 TSTSRYLSLPKNTKLPEKLQKRRTISIADGNSSDSDADAGTTVLNLQPRAR 712
>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
Length = 815
Score = 564 bits (1453), Expect = e-160
Identities = 289/592 (48%), Positives = 403/592 (68%), Gaps = 15/592 (2%)
Query: 52 EPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVG 111
+P + V +DY +V+ P+E++LWILLA L KIGFH+ + ++PESCLLI+VG LVG
Sbjct: 84 KPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVG 143
Query: 112 GIIFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINAL 171
G+I G ++PP + S ++FL+LLPPI+L+ GYF+P R F EN+G+IL +AV+G L NA
Sbjct: 144 GLIKGVG-ETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAF 202
Query: 172 GIGLSLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGE 231
+G +Y +C V + ++ LL NLLFGS+ISAVDPVAVLAVFEE +NE L++++FGE
Sbjct: 203 FLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGE 262
Query: 232 ALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFI 291
+LLND +TVVLY++ F + +E + VDI G F VV LGGVL G+V+G I+AF
Sbjct: 263 SLLNDAVTVVLYHL---FEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFT 319
Query: 292 TRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTI 351
+RFT +I IEPL VF++SY++YL+AE +LSGI+A+ A V M+ YVE N+S S+TTI
Sbjct: 320 SRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTI 379
Query: 352 KYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQF 411
KYF+KM SSVSETLIFIF+GVSTV +H WNW F+ TL FC I R + V L + N+F
Sbjct: 380 KYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKF 439
Query: 412 RTFPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITV 471
R + KDQ II Y G+RGA +FSL +LL FP +F+TA + VI+FTVF+QG+T+
Sbjct: 440 RIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTI 499
Query: 472 GPLVRYLDVKKTNK-KESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLR 530
PLV L VKK + K SINEE+H + +DHL GIED+CGH+ H+ +DK +F+ +Y++
Sbjct: 500 RPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVK 559
Query: 531 KILIRKNLPKS-SIVSLYKKLEMKQAIEMVETGILSSTAFSI---------PHQAQRIQG 580
K LI K +++ Y K+EMKQAIE+VE+G + ++ P +
Sbjct: 560 KCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERI 619
Query: 581 IKRLSPEDVESIRDILTSNMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQ 632
+ LS + E IR IL +N+ + RQR SYN++ L E+ ++L+RRQ
Sbjct: 620 LPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQ 671
>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 3 [Homo sapiens]
Length = 834
Score = 464 bits (1194), Expect = e-130
Identities = 261/626 (41%), Positives = 384/626 (61%), Gaps = 42/626 (6%)
Query: 56 GISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIF 115
G V ++ +VQ PY + LWIL+ASLAKIGFHL H++ ++PES LLI++G ++GGI++
Sbjct: 41 GFQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVW 100
Query: 116 GTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGL 175
DH + + +++F YLLPPIVL+ GYFMP R FF N+G+IL +AV+G + NA GL
Sbjct: 101 AADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGL 160
Query: 176 SLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLN 235
SLY + G + LL LLFGSL++AVDPVAVLAVFEE VNE L++++FGE+LLN
Sbjct: 161 SLYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLN 220
Query: 236 DGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFT 295
D +TVVLYN+ +F + +++ VD + G F VV LGG L G+VF F+ + +TRFT
Sbjct: 221 DAVTVVLYNVFESFVALGG-DNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFT 279
Query: 296 QNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFM 355
+++ IEP VF+ SYLSYL +E L LS ILAIT C + +KYV+ N+S+ S TT++Y M
Sbjct: 280 KHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTM 339
Query: 356 KMLSSVSETLIFIFMGVSTVGK-NHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTF 414
KML+S +ET+IF+F+G+S V WN AF+ TL F ++RAI V ++ N++R
Sbjct: 340 KMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMV 399
Query: 415 PFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPL 474
DQ ++ Y G+RGA +F+L LL K +FV+ T++V++FTV QG+T+ PL
Sbjct: 400 QLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPL 459
Query: 475 VRYLDVKKTNKKE-SINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKIL 533
V++L VK++ +E +NE+LH R DH+ + IED+ G H +RDK+ FD ++L ++L
Sbjct: 460 VQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVL 519
Query: 534 IRKNLPKS--SIVSLYKKLEMKQAIEMVETG--------ILSSTAFSI------PHQAQR 577
+R++ KS I++++ +L +K AI V G I S + ++ P +
Sbjct: 520 MRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTV 579
Query: 578 IQGIKRLSPEDV--------------ESIRD--------ILTSNMYQVRQRTLS-YNKYN 614
+ L E+V SIRD L +Y+ RQ Y+++
Sbjct: 580 EASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHE 639
Query: 615 LKPQTSEKQAKEILIRRQNTLRESMR 640
L P EKQ +EI R ES +
Sbjct: 640 LTPTEDEKQDREIFHRTMRKRLESFK 665
>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 5 [Homo sapiens]
Length = 896
Score = 462 bits (1189), Expect = e-130
Identities = 269/666 (40%), Positives = 396/666 (59%), Gaps = 39/666 (5%)
Query: 52 EPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVG 111
EP G+ +F + V+ PY V LWIL+ASLAKI FHL ++ L+PESCLLIL+G ++G
Sbjct: 29 EPPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLG 88
Query: 112 GIIFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINAL 171
GI+ K+ ++ +FL+LLPPIVL+ GYFMP+R FF+N+G+IL +AV+G L NA
Sbjct: 89 GIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAF 148
Query: 172 GIGLSLYLICQVKAFG-LGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFG 230
G +L+ + Q LL LLFGSLISAVDPVAVLAVFEE VNE L++++FG
Sbjct: 149 TTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFG 208
Query: 231 EALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAF 290
E+LLND +TVVLY + +F +M +++ D L G A VV LGG G+VF F+ A
Sbjct: 209 ESLLNDAVTVVLYKVCNSFVEMGS-ANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLAL 267
Query: 291 ITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTT 350
TRFT+ + IEPL+VF+ +Y +YL AE LS ILA+T C + KKYVE N+S S TT
Sbjct: 268 TTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTT 327
Query: 351 IKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNW--AFICFTLAFCQIWRAISVFALFYIS 408
+KY MK L+S +ET+IF+ +G+S V + +W W + TL F +RA+ V ++
Sbjct: 328 VKYTMKTLASCAETVIFMLLGISAVDSS-KWAWDSGLVLGTLIFILFFRALGVVLQTWVL 386
Query: 409 NQFRTFPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQG 468
NQFR P DQ ++ Y G+RGA +F+L LL + P K FV T+VV++FTV +QG
Sbjct: 387 NQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQG 446
Query: 469 ITVGPLVRYLDVKKT-NKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHR 527
+T+ PLV++L VK++ + K ++N+ELH DH+ A +EDV GH ++ RD++++FD +
Sbjct: 447 LTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKK 506
Query: 528 YLRKILIRKNL--PKSSIVSLYKKLEMKQAIEMVETG--ILSSTAFSIPHQAQR------ 577
YL ++L+R++ + I +Y +L ++ AI V+ G +LSST ++P R
Sbjct: 507 YLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGHVLSSTGLTLPSMPSRNSVAET 566
Query: 578 -IQGIKRLSP----------EDVESIRD--------ILTSNMYQVRQR-TLSYNKYNLKP 617
+ + R S + V S RD +L +Y+ R+R S +++ +
Sbjct: 567 SVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISE 626
Query: 618 QTSEKQAKEILIRRQNTLRESMRK-GHSLPW--GKPAGTKNIRYLSYPYGNPQSAGRDTR 674
E+Q KE+ + ES + H++ + KP K R N ++ R
Sbjct: 627 DAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSKPRPRKTGRRKKDGVANAEATNGKHR 686
Query: 675 AAGFSD 680
GF D
Sbjct: 687 GLGFQD 692
>gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]
Length = 581
Score = 221 bits (563), Expect = 2e-57
Identities = 144/481 (29%), Positives = 254/481 (52%), Gaps = 25/481 (5%)
Query: 77 ILLASLAKIGFHLYHRLP-GLMPESCLLILVGALVGGIIFGTDHKS------PPVMDSSI 129
+L+ ++ I HL R +PES ++ +G L+G +I + K + ++
Sbjct: 66 LLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEMFRPNM 125
Query: 130 YFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLICQVKAFGLG 189
+FL LLPPI+ E GY + FF+NIGSI +AV G I+A +G +Y + Q +
Sbjct: 126 FFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQADV--IS 183
Query: 190 DVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAF 249
+N+ + FGSLISAVDPVA +A+F V+ L M++FGE++LND +++VL N
Sbjct: 184 KLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGL 243
Query: 250 TKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFT--QNISAIEPLIVF 307
T+ + + L F+ + G G + G ISA + + + ++E ++
Sbjct: 244 TRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMI 303
Query: 308 MFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIF 367
+F+YL Y AE + LSGI+AI + M Y N+S + ++ ++ ++ + ET +F
Sbjct: 304 IFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVF 363
Query: 368 IFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKDQCIIFYS 427
F+G+S H++ +F+ + + RA+++F L Y+ N FR + K I+++S
Sbjct: 364 AFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFS 423
Query: 428 GVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDVK-----K 482
G+RGA ++L+ L L ++++ T T+V++ FT+ + G + PL+R +D++ +
Sbjct: 424 GLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHR 483
Query: 483 TNKKE---SINEELHIRL-MDHLKAGIEDVCGHWSHYQVRDKFKKF---DHRYLRKILIR 535
NKK+ S E++ + +HL E+ + +HY R K F D +YL R
Sbjct: 484 RNKKDVNLSKTEKMGNTVESEHLSELTEE--EYEAHYIRRQDLKGFVWLDAKYLNPFFTR 541
Query: 536 K 536
+
Sbjct: 542 R 542
>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
member 9 [Homo sapiens]
Length = 645
Score = 200 bits (509), Expect = 4e-51
Identities = 130/427 (30%), Positives = 218/427 (51%), Gaps = 22/427 (5%)
Query: 126 DSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLY--LICQV 183
D I+F LLPPI+ GY + R FF+N+GSIL +A LG I+ + IGL +Y + +
Sbjct: 130 DPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMI 189
Query: 184 KAFGL--GDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVV 241
A L GD + L FGSL+SA DPV VLA+F E V+ LY ++FGE++LND + +V
Sbjct: 190 HAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIV 249
Query: 242 LYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQ--NIS 299
L + ++ + F+ + G G + I+A +T+FT+
Sbjct: 250 LTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFP 309
Query: 300 AIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLS 359
+E + F+ S+ ++L+AE L+GI+A+ C VT Y N+S S K + ++
Sbjct: 310 MLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMN 369
Query: 360 SVSETLIFIFMGVST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSI 418
++E +IF +MG++ +NH +N FI + RA +++ L ++ N R
Sbjct: 370 FLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPW 429
Query: 419 KDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYL 478
Q ++ +SG+RGA +F+LA S K+M T TL++++FTV++ G P++ +L
Sbjct: 430 NFQHMMMFSGLRGAIAFALAIRNTES--QPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWL 487
Query: 479 ------DVKKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKI 532
D+ + K++ ++ +D E ++ + FDH+YL+ I
Sbjct: 488 QIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESA-------RLFRMWYSFDHKYLKPI 540
Query: 533 LIRKNLP 539
L P
Sbjct: 541 LTHSGPP 547
>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform b [Homo sapiens]
Length = 669
Score = 199 bits (505), Expect = 1e-50
Identities = 151/528 (28%), Positives = 262/528 (49%), Gaps = 42/528 (7%)
Query: 41 ASNAWFAAASSEPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLY-HRLPGLMPE 99
AS+ A + EE +S + + + Q + ++ILL +L + L+ HR + E
Sbjct: 42 ASDGGGGEARAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHE 101
Query: 100 SCLLILVGALVG-----GIIFGTD----------HKSPPVM----DSSIYFLYLLPPIVL 140
+ L ++ G LVG GI +D SP + D ++F LLPPI+
Sbjct: 102 TGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIF 161
Query: 141 EGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLY-LICQVKAFG--LGDVNLLQNL 197
GY + R FF N+GSIL +A LG I+ IG +Y + +K G GD L
Sbjct: 162 YAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCL 221
Query: 198 LFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFED 257
LFG+++SA DPV VLA+F E +V+ +LY ++FGE++LND + +VL + ++A+ ++
Sbjct: 222 LFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAG--DN 279
Query: 258 IETVDILA---GCARFIVVGLGGVLFGIVFGFISAFITRFT--QNISAIEPLIVFMFSYL 312
T D+ A F+ + G G G ++A +T+FT + +E + F+ S+
Sbjct: 280 SHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWS 339
Query: 313 SYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGV 372
++L AE +G++A+ C +T Y N+S S K ++L+ ++E IF +MG+
Sbjct: 340 TFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGL 399
Query: 373 ST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKDQCIIFYSGVRG 431
+ +NH +N F+ + RA +++ L + N R Q ++ ++G+RG
Sbjct: 400 TLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRG 459
Query: 432 AGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDVKKTNKKESINE 491
A +F+LA + + + R+ MF T TL++++FTV++ G ++ L ++ +S E
Sbjct: 460 AMAFALA-IRDTATYARQMMFST-TLLIVFFTVWVFGGGTTAMLSCLHIRV--GVDSDQE 515
Query: 492 ELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLP 539
L + + E W + + FDH YL+ +L P
Sbjct: 516 HLGVPENERRTTKAESA---W----LFRMWYNFDHNYLKPLLTHSGPP 556
>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform a [Homo sapiens]
Length = 701
Score = 189 bits (479), Expect = 1e-47
Identities = 126/423 (29%), Positives = 219/423 (51%), Gaps = 22/423 (5%)
Query: 126 DSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLY-LICQVK 184
D ++F LLPPI+ GY + R FF N+GSIL +A LG I+ IG +Y + +K
Sbjct: 179 DPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMK 238
Query: 185 AFG--LGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVL 242
G GD LLFG+++SA DPV VLA+F E +V+ +LY ++FGE++LND + +VL
Sbjct: 239 VTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 298
Query: 243 YNMLIAFTKMHKFEDIETVDILA---GCARFIVVGLGGVLFGIVFGFISAFITRFT--QN 297
+ ++A+ ++ T D+ A F+ + G G G ++A +T+FT +
Sbjct: 299 SSSIVAYQPAG--DNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLRE 356
Query: 298 ISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKM 357
+E + F+ S+ ++L AE +G++A+ C +T Y N+S S K ++
Sbjct: 357 FQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFEL 416
Query: 358 LSSVSETLIFIFMGVST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPF 416
L+ ++E IF +MG++ +NH +N F+ + RA +++ L + N R
Sbjct: 417 LNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKI 476
Query: 417 SIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVR 476
Q ++ ++G+RGA +F+LA + + + R+ MF T TL++++FTV++ G ++
Sbjct: 477 GSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFST-TLLIVFFTVWVFGGGTTAMLS 534
Query: 477 YLDVKKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRK 536
L ++ +S E L + + E W + + FDH YL+ +L
Sbjct: 535 CLHIRV--GVDSDQEHLGVPENERRTTKAESA---W----LFRMWYNFDHNYLKPLLTHS 585
Query: 537 NLP 539
P
Sbjct: 586 GPP 588
>gi|14211919 solute carrier family 9, member 7 [Homo sapiens]
Length = 725
Score = 177 bits (448), Expect = 4e-44
Identities = 130/448 (29%), Positives = 224/448 (50%), Gaps = 41/448 (9%)
Query: 126 DSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLICQV-K 184
D ++F LLPPI+ GY + R FF N+GSIL +A LG ++ IG +Y + ++ K
Sbjct: 179 DPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMK 238
Query: 185 AFG-LGDVNLLQN-LLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVL 242
G L D + L FG++ISA DPV VLA+F E + LY ++FGE++LND + +VL
Sbjct: 239 IMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVL 298
Query: 243 YNMLIAF----TKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQ-- 296
+ ++A+ H F + F+ + G G V G ++A +T+FT+
Sbjct: 299 SSSIVAYQPAGLNTHAF---DAAAFFKSVGIFLGIFSGSFTMGAVTG-VNANVTKFTKLH 354
Query: 297 NISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMK 356
+E + F+ S+ ++L AE +G++A+ C +T Y N+S S + K +
Sbjct: 355 CFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFE 414
Query: 357 MLSSVSETLIFIFMGVST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFP 415
+L ++E IF +MG++ + H ++ FI + RA ++ L + N R
Sbjct: 415 VLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHK 474
Query: 416 FSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLV 475
Q ++ +SG+RGA +F+LA + + + R+ MF T TL++++FTV+I G P++
Sbjct: 475 IGWNFQHMMMFSGLRGAMAFALA-IRDTASYARQMMF-TTTLLIVFFTVWIIGGGTTPML 532
Query: 476 RYLDVKKTNKKESINEELHIRLMDHLKAGI---EDVCGHWSHYQV------------RDK 520
+L++ + +E E+ + + + G+ +D + +QV R K
Sbjct: 533 SWLNI-RVGVEEPSEEDQNEHHWQYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTK 591
Query: 521 ---------FKKFDHRYLRKILIRKNLP 539
+ FDH YL+ IL P
Sbjct: 592 QESAWIFRLWYSFDHNYLKPILTHSGPP 619
>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
Length = 1177
Score = 57.8 bits (138), Expect = 4e-08
Identities = 67/311 (21%), Positives = 133/311 (42%), Gaps = 33/311 (10%)
Query: 77 ILLASLAKIGFHLYHRLPGL-MPESCLLILVGALVGGIIFGTDH-----KSPPVMDSSIY 130
+ L+ ++ IG L L +P +L L+G + F + + M ++
Sbjct: 20 LTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLF 79
Query: 131 FLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLICQVKAFGLGD 190
F P + + M T + IL ++ G L+N + L L+ + V L
Sbjct: 80 FRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYI---LVLWHLASVNQLLLKP 136
Query: 191 VNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFT 250
Q LLF +++ + DP+ A + ++ L +I GE+L+ I+++ + ++ F
Sbjct: 137 T---QWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFD 193
Query: 251 KMHKFEDIETV--DILAGCARFIVVGLGGVLFGIVFGFISAF--ITRFTQNISAIEPLIV 306
+ + + T+ +I+ G +I+ LFGI+ + F T F +++ I ++
Sbjct: 194 QRLQSKRNHTLAEEIVGGICSYIIASF---LFGILSSKLIQFWMSTVFGDDVNHIS--LI 248
Query: 307 FMFSYLSYLAAETLYLSGILAITAC-----AVTMKKYVEENVSQTSYTTIKYFMKMLSSV 361
F YL + E + +SGI + + + K +EE T + F LS +
Sbjct: 249 FSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEE-------TLLLEFWTFLSRI 301
Query: 362 SETLIFIFMGV 372
+ ++F F G+
Sbjct: 302 AFLMVFTFFGL 312
>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
Length = 1124
Score = 47.8 bits (112), Expect = 4e-05
Identities = 88/410 (21%), Positives = 174/410 (42%), Gaps = 65/410 (15%)
Query: 102 LLILVGALVGGIIFGTDHKSP---PVMDSSIYFLY-LLPPIVLEGGYFMPTRPFFENIGS 157
+L L G ++G + + + P++ +S + LY P+++ + + F +
Sbjct: 59 ILSLSGFVIGHMAYNSVEVHQIVYPLLRTSSFSLYSYFSPLII---FMVALDVEFYTLKK 115
Query: 158 ILWWAVLGALINALGIGLSLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEE 217
+ W +L LI+ + + + V F +L LLF + +DP+ + +
Sbjct: 116 MFWQVLLTGLISFSTASIIIGYV--VIKFNKDSWDLQSCLLFSITLGIIDPLRSVNSLKT 173
Query: 218 ARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLG- 276
+++ +I GE+L+ I + F + I R + VG+
Sbjct: 174 IGISKIYIDLIRGESLIICSIASIF------------FGNFRGNRIHFSIFRDLHVGIEL 221
Query: 277 --GVLFGIVFGFISAFITR------FTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAI 328
+L I+FG+ A I + F+ ++ I ++ F Y+++ E L +SG LA+
Sbjct: 222 SYDILGSIIFGYWCAKIIQCILADVFSNMLTNI--ILCFSMVYMTFYIVEFLGMSGTLAL 279
Query: 329 TAC-----AVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTVG------- 376
A ++T K +E I F+++ SSV E LI+ F G+ +G
Sbjct: 280 AAVGLNLDSLTFKPKIE--------LVITKFLRIFSSVYEHLIYAFFGI-VIGCGELSHY 330
Query: 377 KNHEWNWAFICF-TLAFCQIWRAISVFALFYISNQFRTFPFSIKDQCIIFYSGVRGAGSF 435
+ H + FI F T+ ++ + V + SN + ++ + +I +SG++G F
Sbjct: 331 EFHTIPFIFILFTTVNLVRLLTILLVSPILMHSN----YEYNWRWGVVITWSGIKGV--F 384
Query: 436 SLAFLLPL-SLFPRK----KMFVTATLVVIYFTVFIQGITVGPLVRYLDV 480
+L + + +L RK +MF+ V+ T+ I + R LD+
Sbjct: 385 NLLWAPDVYNLAERKVEVPQMFILYVQVISLLTMGINSYVMTQSARKLDL 434
>gi|46409360 G protein-coupled receptor 148 [Homo sapiens]
Length = 347
Score = 32.3 bits (72), Expect = 1.8
Identities = 31/141 (21%), Positives = 66/141 (46%), Gaps = 24/141 (17%)
Query: 185 AFGLGDVNLLQNLLF-----GSLISA----VDPVAVLAVFEEARVNEQLYMMIFGEALLN 235
+ GLGD+ + ++L+ SL++A V P+ ++ + R+ ++ + ++ LL+
Sbjct: 36 SLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLS 95
Query: 236 DGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFT 295
D + +L +MLI+ + + +E L A G+L VF ++ I FT
Sbjct: 96 D-LAYILLHMLISSSSLGGWE-------LGRMA-------CGILTDAVFAACTSTILSFT 140
Query: 296 QNISAIEPLIVFMFSYLSYLA 316
+ ++ YLS+++
Sbjct: 141 AIVLHTYLAVIHPLRYLSFMS 161
>gi|224451040 Yip1 interacting factor homolog B isoform 7 [Homo
sapiens]
Length = 291
Score = 30.8 bits (68), Expect = 5.2
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 167 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 224
Query: 269 RFIVVGLGGVLFGIVFGFISAFITRFTQNISAIEPLIVFMFSYL 312
V +GGVL G++FG I ++ ++ + VFMF L
Sbjct: 225 YKYVGMIGGVLMGLLFGKIGYYLVLGWCCVA----IFVFMFPLL 264
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 30.8 bits (68), Expect = 5.2
Identities = 25/117 (21%), Positives = 57/117 (48%), Gaps = 10/117 (8%)
Query: 521 FKKFDHRYLRKILIRKNLPKSSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQG 580
F+ + + +K+ I + + + LY+KL +++ + E LS I H + ++
Sbjct: 373 FESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELET 432
Query: 581 IKRLSPEDVESIRDILTSNMYQVRQRTLSYNKYN----LKPQTSEKQAKEILIRRQN 633
++L+ + E + T + YQ ++ +SY K L +T+E+ + +R++N
Sbjct: 433 YRKLAKDLEEELE--RTVHFYQ--KQVISYEKRGHDNWLAARTAERNLSD--LRKEN 483
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 30.8 bits (68), Expect = 5.2
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 11/105 (10%)
Query: 644 SLPWGKPAGTKNIRYLSYPYGNPQSAGRDTRAAGFSDDDSSDPGSPSITFSACSRIGSLQ 703
S P P + RYL YG + R+ R ++ +S G P SR GSL
Sbjct: 47 SFPSPSPFPNYDYRYLQQKYGESCAEAREKRVPAWNAQRASTRGPP-------SRKGSLS 99
Query: 704 KQEAQEII----PMKSLHRGRKAFSFGYQRNTSQEEYLGGVRRVA 744
++ E I P++ + R +G R + + L + V+
Sbjct: 100 IEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVS 144
>gi|7657465 podocalyxin-like 2 [Homo sapiens]
Length = 605
Score = 30.8 bits (68), Expect = 5.2
Identities = 16/45 (35%), Positives = 24/45 (53%)
Query: 92 RLPGLMPESCLLILVGALVGGIIFGTDHKSPPVMDSSIYFLYLLP 136
RLP L+ LL++ GA +G + G+D P + S+ LLP
Sbjct: 9 RLPPLLSPLLLLLVGGAFLGACVAGSDEPGPEGLTSTSLLDLLLP 53
>gi|224451038 Yip1 interacting factor homolog B isoform 2 [Homo
sapiens]
Length = 283
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 139 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 196
Query: 269 RFIVVGLGGVLFGIVFGFISAFI 291
V +GGVL G++FG I ++
Sbjct: 197 YKYVGMIGGVLMGLLFGKIGYYL 219
>gi|224451034 Yip1 interacting factor homolog B isoform 6 [Homo
sapiens]
Length = 297
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 153 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 210
Query: 269 RFIVVGLGGVLFGIVFGFISAFI 291
V +GGVL G++FG I ++
Sbjct: 211 YKYVGMIGGVLMGLLFGKIGYYL 233
>gi|24308364 Yip1 interacting factor homolog B isoform 2 [Homo
sapiens]
Length = 283
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 139 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 196
Query: 269 RFIVVGLGGVLFGIVFGFISAFI 291
V +GGVL G++FG I ++
Sbjct: 197 YKYVGMIGGVLMGLLFGKIGYYL 219
>gi|89191845 Yip1 interacting factor homolog B isoform 3 [Homo
sapiens]
Length = 299
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 155 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 212
Query: 269 RFIVVGLGGVLFGIVFGFISAFI 291
V +GGVL G++FG I ++
Sbjct: 213 YKYVGMIGGVLMGLLFGKIGYYL 235
>gi|89191850 Yip1 interacting factor homolog B isoform 4 [Homo
sapiens]
Length = 311
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 167 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 224
Query: 269 RFIVVGLGGVLFGIVFGFISAFI 291
V +GGVL G++FG I ++
Sbjct: 225 YKYVGMIGGVLMGLLFGKIGYYL 247
>gi|89191848 Yip1 interacting factor homolog B isoform 5 [Homo
sapiens]
Length = 314
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 209 VAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCA 268
VA LA+ + R + L + AL +T+ + +L++ + D+ T+D++A
Sbjct: 170 VAGLALGTQDRFSPDLLGLQASSALA--WLTLEVLAILLSLYLVTVNTDLTTIDLVAFLG 227
Query: 269 RFIVVGLGGVLFGIVFGFISAFI 291
V +GGVL G++FG I ++
Sbjct: 228 YKYVGMIGGVLMGLLFGKIGYYL 250
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,944,551
Number of Sequences: 37866
Number of extensions: 1218103
Number of successful extensions: 3260
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3208
Number of HSP's gapped (non-prelim): 26
length of query: 798
length of database: 18,247,518
effective HSP length: 110
effective length of query: 688
effective length of database: 14,082,258
effective search space: 9688593504
effective search space used: 9688593504
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.