Guide to the Human Genome
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Search of human proteins with 148664186

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
         (837 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]                 1657   0.0  
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]                 1636   0.0  
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]                   362   e-100
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ...   362   e-100
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]                   350   3e-96
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...   300   5e-81
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                    295   2e-79
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                    295   2e-79
gi|6005830 plakophilin 3 [Homo sapiens]                               291   1e-78
gi|4502247 armadillo repeat protein [Homo sapiens]                    265   2e-70
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]               263   5e-70
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]               263   5e-70
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]               263   5e-70
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]               263   5e-70
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]              263   5e-70
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]               263   5e-70
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]               263   5e-70
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]               263   5e-70
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                263   5e-70
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]              263   5e-70
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]              256   5e-68
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]             256   5e-68
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]             256   5e-68
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 43   0.001
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 43   0.001
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  43   0.001
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              42   0.003
gi|7662162 ALEX2 protein [Homo sapiens]                                41   0.004
gi|29540562 ALEX2 protein [Homo sapiens]                               41   0.004
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]     40   0.012

>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
          Length = 837

 Score = 1657 bits (4291), Expect = 0.0
 Identities = 837/837 (100%), Positives = 837/837 (100%)

Query: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60
           MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV
Sbjct: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60

Query: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120
           QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE
Sbjct: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120

Query: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180
           GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH
Sbjct: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180

Query: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240
           QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL
Sbjct: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240

Query: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300
           LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT
Sbjct: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300

Query: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360
           LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML
Sbjct: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360

Query: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420
           EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR
Sbjct: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420

Query: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEAL 480
           NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEAL
Sbjct: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEAL 480

Query: 481 LTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLID 540
           LTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLID
Sbjct: 481 LTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLID 540

Query: 541 SLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKS 600
           SLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKS
Sbjct: 541 SLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKS 600

Query: 601 IGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLG 660
           IGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLG
Sbjct: 601 IGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLG 660

Query: 661 ALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQN 720
           ALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQN
Sbjct: 661 ALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQN 720

Query: 721 EIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMA 780
           EIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMA
Sbjct: 721 EIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMA 780

Query: 781 ISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 837
           ISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD
Sbjct: 781 ISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 837


>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
          Length = 881

 Score = 1636 bits (4236), Expect = 0.0
 Identities = 837/881 (95%), Positives = 837/881 (95%), Gaps = 44/881 (4%)

Query: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60
           MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV
Sbjct: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60

Query: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120
           QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE
Sbjct: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120

Query: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180
           GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH
Sbjct: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180

Query: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240
           QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL
Sbjct: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240

Query: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300
           LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT
Sbjct: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300

Query: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360
           LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML
Sbjct: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360

Query: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420
           EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR
Sbjct: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420

Query: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQIT--------------------- 459
           NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQIT                     
Sbjct: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACN 480

Query: 460 -----------------------GLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 496
                                  GLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE
Sbjct: 481 PSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 540

Query: 497 GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD 556
           GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD
Sbjct: 541 GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD 600

Query: 557 DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ 616
           DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ
Sbjct: 601 DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ 660

Query: 617 DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV 676
           DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV
Sbjct: 661 DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV 720

Query: 677 AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD 736
           AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD
Sbjct: 721 AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD 780

Query: 737 TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA 796
           TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA
Sbjct: 781 TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA 840

Query: 797 SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 837
           SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD
Sbjct: 841 SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 881


>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
          Length = 726

 Score =  362 bits (930), Expect = e-100
 Identities = 198/482 (41%), Positives = 300/482 (62%), Gaps = 10/482 (2%)

Query: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290

Query: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350

Query: 459 TGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCL 518
           TGLLWNLSS D+LK  +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCL
Sbjct: 351 TGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 410

Query: 519 RNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAEL 578
           RN+SSA A GR+ MR   GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+L+AE+
Sbjct: 411 RNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEV 469

Query: 579 PEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIV 638
           P +Y Q  Y   RN  T+ + S GCF ++S K+     D P+PEE++NPKG  WL+HS  
Sbjct: 470 PTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDA 527

Query: 639 IRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGD 698
           IR YL+L+ KS ++ T EA  GALQNLTA  G M + ++Q +  KE GL    ++L  G+
Sbjct: 528 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN 587

Query: 699 PSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNI 758
             V ++  SLL N+SR+  L   +  +  P++  ++     +T    +  +SACYT+ N+
Sbjct: 588 SDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNL 647

Query: 759 IQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQF 818
           + +  Q A+   ++  +  I+ +      AS KA++AA +LL  +W+  EL    ++  F
Sbjct: 648 MASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGF 705

Query: 819 KK 820
            +
Sbjct: 706 DR 707



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)

Query: 13  IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
           ++T L  +     D+S+LALPS+ K+K  G+SGR        R+QEQV  T+ R+   S 
Sbjct: 6   LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57

Query: 73  GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
            +  L  ++    Y      + +++  G +     Y   +AG      G WG     GT 
Sbjct: 58  QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108

Query: 128 ------AQYSSQKSVEERSLRHP 144
                  ++SS   +E  S  +P
Sbjct: 109 KREPDNRRFSSYSQMENWSRHYP 131


>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
           sapiens]
          Length = 625

 Score =  362 bits (930), Expect = e-100
 Identities = 198/482 (41%), Positives = 300/482 (62%), Gaps = 10/482 (2%)

Query: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 132 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 189

Query: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 190 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 249

Query: 459 TGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCL 518
           TGLLWNLSS D+LK  +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCL
Sbjct: 250 TGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 309

Query: 519 RNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAEL 578
           RN+SSA A GR+ MR   GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+L+AE+
Sbjct: 310 RNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEV 368

Query: 579 PEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIV 638
           P +Y Q  Y   RN  T+ + S GCF ++S K+     D P+PEE++NPKG  WL+HS  
Sbjct: 369 PTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDA 426

Query: 639 IRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGD 698
           IR YL+L+ KS ++ T EA  GALQNLTA  G M + ++Q +  KE GL    ++L  G+
Sbjct: 427 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN 486

Query: 699 PSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNI 758
             V ++  SLL N+SR+  L   +  +  P++  ++     +T    +  +SACYT+ N+
Sbjct: 487 SDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNL 546

Query: 759 IQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQF 818
           + +  Q A+   ++  +  I+ +      AS KA++AA +LL  +W+  EL    ++  F
Sbjct: 547 MASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGF 604

Query: 819 KK 820
            +
Sbjct: 605 DR 606


>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
          Length = 747

 Score =  350 bits (898), Expect = 3e-96
 Identities = 198/503 (39%), Positives = 300/503 (59%), Gaps = 31/503 (6%)

Query: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290

Query: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350

Query: 459 TGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCL 518
           TGLLWNLSS D+LK  +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCL
Sbjct: 351 TGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 410

Query: 519 R---------------------NMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDD 557
           R                     N+SSA A GR+ MR   GLIDSL+ YV+  +A  + DD
Sbjct: 411 RKRLGMRELLALVPQRATSSRVNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDD 469

Query: 558 KATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQD 617
           K+ ENC+C+LHNLSY+L+AE+P +Y Q  Y   RN  T+ + S GCF ++S K+     D
Sbjct: 470 KSVENCMCVLHNLSYRLDAEVPTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYD 527

Query: 618 VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVA 677
            P+PEE++NPKG  WL+HS  IR YL+L+ KS ++ T EA  GALQNLTA  G M + ++
Sbjct: 528 CPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMS 587

Query: 678 QTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDT 737
           Q +  KE GL    ++L  G+  V ++  SLL N+SR+  L   +  +  P++  ++   
Sbjct: 588 QLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSH 647

Query: 738 VPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAAS 797
             +T    +  +SACYT+ N++ +  Q A+   ++  +  I+ +      AS KA++AA 
Sbjct: 648 TGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAAR 705

Query: 798 VLLYSLWAHTELHHAYKKAQFKK 820
           +LL  +W+  EL    ++  F +
Sbjct: 706 LLLSDMWSSKELQGVLRQQGFDR 728



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)

Query: 13  IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
           ++T L  +     D+S+LALPS+ K+K  G+SGR        R+QEQV  T+ R+   S 
Sbjct: 6   LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57

Query: 73  GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
            +  L  ++    Y      + +++  G +     Y   +AG      G WG     GT 
Sbjct: 58  QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108

Query: 128 ------AQYSSQKSVEERSLRHP 144
                  ++SS   +E  S  +P
Sbjct: 109 KREPDNRRFSSYSQMENWSRHYP 131


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
            plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score =  300 bits (767), Expect = 5e-81
 Identities = 223/695 (32%), Positives = 343/695 (49%), Gaps = 53/695 (7%)

Query: 163  HSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQ 222
            H+  QYS+        H QE    A L  P      +   SRA  +S+  H     R  Q
Sbjct: 367  HASEQYSK--------HSQELYATATLQRP----GSLAAGSRASYSSQHGHLGPELRALQ 414

Query: 223  HGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQ 282
                 +   D I  +      P    S+S G+ L   +  T   +     P V   P+ +
Sbjct: 415  S---PEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471

Query: 283  NRASRSSWHQSSFHSTRTLREAGP-SVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTD 341
              +     + ++    R    AGP S   D   +  +    ++    SG  L    T   
Sbjct: 472  TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531

Query: 342  S-----------QLGNADMEMTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKR 390
            S           + G  D E  L   + ML+  H  PS  S AA ++QH CF  ++ +  
Sbjct: 532  SPSIDSIQKDPREFGWRDPE--LPEVIQMLQ--HQFPSVQSNAAAYLQHLCFGDNKIKAE 587

Query: 391  VNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQ 448
            + +  GI  L+ LL  +  +V R+ CGALRNLV+   ++DNK+ +    G+P L+++L++
Sbjct: 588  IRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRK 647

Query: 449  TRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKANGL 505
            T DLE ++ +TG+LWNLSS D LK  +I +AL  LT  +IIP SGW   P  D  K   L
Sbjct: 648  TTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ-L 706

Query: 506  LDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVC 565
                +  N TGCLRN+SSAG + R+ MR CDGL D+L++ ++  +   + D K  ENCVC
Sbjct: 707  HSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVC 766

Query: 566  ILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNN----KSIGCFGSRSRKVKEQYQ---DV 618
            IL NLSY+L AE  +         +  +  + N    +S GC+G + +K K Q Q     
Sbjct: 767  ILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVG 826

Query: 619  PMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQ 678
            P+P+    PKG++ LWH  +++ YL+L+++     T E + GALQNL AGS      + +
Sbjct: 827  PLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYI-R 885

Query: 679  TVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIP--- 735
              V+KE GL    ++L + +  V     + LRN++ ++  +  I K  + DLV  +P   
Sbjct: 886  AAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGN 945

Query: 736  --DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAI--SAGDAYASNK 791
              +   S  +  +T  + C TL+ +I  + +NA+ L + GGI+K++ I  S GD + S K
Sbjct: 946  NSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKH-SPK 1004

Query: 792  ASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVNS 826
              KAAS +L S+W + +L   YKK  + +  FV S
Sbjct: 1005 VVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVAS 1039


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score =  295 bits (754), Expect = 2e-79
 Identities = 176/489 (35%), Positives = 282/489 (57%), Gaps = 23/489 (4%)

Query: 353  LERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQ 412
            L   + ML+  H  PS  + AA ++QH CF  ++ +  V +L GI  L+ LL  +  +VQ
Sbjct: 530  LPEVIHMLQ--HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQ 587

Query: 413  RAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDK 470
            +  CGALRNLVF    ++NK+ +  + G+P LL++L+++ D E ++ +TG+LWNLSS D 
Sbjct: 588  KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDA 647

Query: 471  LKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFD---IFYNVTGCLRNMSSAGAD 527
            +K  +I +AL TLT  +I+P SGW    +   + +  F    +  N TGCLRN+SSAG +
Sbjct: 648  VKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKI-KFQTSLVLRNTTGCLRNLSSAGEE 706

Query: 528  GRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNI- 586
             RK MR C+GL+DSL++ +   +     D K  ENCVC L NLSY+LE E+P+     + 
Sbjct: 707  ARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLN 766

Query: 587  ----YIQNRNIQTDNNKSIGCFGSRSRKVK-----EQYQDV-PMPEEKSNPKGVEWLWHS 636
                 +   +   D+  S  C+G + +K K     +Q+  V P+P    +PKGVE LWH 
Sbjct: 767  ELDDLLGKESPSKDSEPS--CWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHP 824

Query: 637  IVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHV 696
             V++ YL+L+A+S    T E S G+LQNL+AG+      + +  V+KE GL    ++L +
Sbjct: 825  SVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLRM 883

Query: 697  GDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLN 756
             +  V  +  + LRN++ ++  +  I K  + DLV+ +P     + L  ET A+ C  L+
Sbjct: 884  DNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALH 943

Query: 757  NIIQNSYQNARDLLNTGGIQKIMAISAGDAYASN-KASKAASVLLYSLWAHTELHHAYKK 815
             +   + +NA+ L ++GGI+K++ I+ G    S+ K  KAA+ +L +LW + +L   YKK
Sbjct: 944  EVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKK 1003

Query: 816  AQFKKTDFV 824
              + +  F+
Sbjct: 1004 DGWNQNHFI 1012


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score =  295 bits (754), Expect = 2e-79
 Identities = 176/489 (35%), Positives = 282/489 (57%), Gaps = 23/489 (4%)

Query: 353  LERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQ 412
            L   + ML+  H  PS  + AA ++QH CF  ++ +  V +L GI  L+ LL  +  +VQ
Sbjct: 530  LPEVIHMLQ--HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQ 587

Query: 413  RAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDK 470
            +  CGALRNLVF    ++NK+ +  + G+P LL++L+++ D E ++ +TG+LWNLSS D 
Sbjct: 588  KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDA 647

Query: 471  LKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFD---IFYNVTGCLRNMSSAGAD 527
            +K  +I +AL TLT  +I+P SGW    +   + +  F    +  N TGCLRN+SSAG +
Sbjct: 648  VKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKI-KFQTSLVLRNTTGCLRNLSSAGEE 706

Query: 528  GRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNI- 586
             RK MR C+GL+DSL++ +   +     D K  ENCVC L NLSY+LE E+P+     + 
Sbjct: 707  ARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLN 766

Query: 587  ----YIQNRNIQTDNNKSIGCFGSRSRKVK-----EQYQDV-PMPEEKSNPKGVEWLWHS 636
                 +   +   D+  S  C+G + +K K     +Q+  V P+P    +PKGVE LWH 
Sbjct: 767  ELDDLLGKESPSKDSEPS--CWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHP 824

Query: 637  IVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHV 696
             V++ YL+L+A+S    T E S G+LQNL+AG+      + +  V+KE GL    ++L +
Sbjct: 825  SVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLRM 883

Query: 697  GDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLN 756
             +  V  +  + LRN++ ++  +  I K  + DLV+ +P     + L  ET A+ C  L+
Sbjct: 884  DNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALH 943

Query: 757  NIIQNSYQNARDLLNTGGIQKIMAISAGDAYASN-KASKAASVLLYSLWAHTELHHAYKK 815
             +   + +NA+ L ++GGI+K++ I+ G    S+ K  KAA+ +L +LW + +L   YKK
Sbjct: 944  EVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKK 1003

Query: 816  AQFKKTDFV 824
              + +  F+
Sbjct: 1004 DGWNQNHFI 1012


>gi|6005830 plakophilin 3 [Homo sapiens]
          Length = 797

 Score =  291 bits (746), Expect = 1e-78
 Identities = 231/819 (28%), Positives = 388/819 (47%), Gaps = 65/819 (7%)

Query: 29  SLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVY 88
           SLALPS+ +L   G+ G   + +++ R+QEQV+  L + G+    NG     ++ PE   
Sbjct: 19  SLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQPRHNG-----AAEPE--- 70

Query: 89  NLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRL 148
                E +   G S     Y  L+AG ++  +G  G  T+ +             P+ + 
Sbjct: 71  ----PEAETARGTSR--GQYHTLQAGFSSRSQGLSGDKTSGF------------RPIAKP 112

Query: 149 EISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTT 208
             SP S   R+    S  +    +  G +         A   PP   R   V     G  
Sbjct: 113 AYSPASWSSRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRP--VSFHERGGV 170

Query: 209 SRQRHFDTYHRQY----------QHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEK 258
             +  +DT   +           ++  VS+ +  +  +      Y R  +S S       
Sbjct: 171 GSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSR----- 225

Query: 259 ENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAH 318
                 GL   +   + P + +           QSS H +R +  A P   ++   R   
Sbjct: 226 ----AGGLDWPEATEVSPSRTIRAPAVRTLQRFQSS-HRSRGVGGAVPGAVLEPVARAPS 280

Query: 319 LTVGQAAAGGSGNLLTER------STFTDSQLGNADMEMTLERAVSMLEADHMLPSRISA 372
           +     +   SG+L          S  T  +L +   ++ L  AV  L A    P+    
Sbjct: 281 VRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASD--PNLQVL 338

Query: 373 AATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLE 432
            A +IQH+C+  + A+K+   L+ + +L++L    N++VQR   GA+RNL++++ DNKL 
Sbjct: 339 GAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLA 398

Query: 433 VAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFS 492
           + E NG+  LL+ L++  D E +K +TG+LWNLSS+D LK+ +  + L  LT+ ++ P S
Sbjct: 399 LVEENGIFELLRTLREQDD-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLS 457

Query: 493 GWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIAD 552
           G       + N   + +IFYN TG LRN+SSA    R+ MR C GL+D+LV  +   +  
Sbjct: 458 GAGGPPLIQQNAS-EAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDA 516

Query: 553 YQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRN--IQTDNNKSIGCFGSRSRK 610
            + +DK+ EN VC+L NLSY+L  E+P    Q +  + R         + +GCF  +SR+
Sbjct: 517 GKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRR 576

Query: 611 VKE---QYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAK-SVRNYTQEASLGALQNLT 666
           ++E       +   E   +PKG+EWLW   ++ +Y  L+ +  +  +T EA+ GALQN+T
Sbjct: 577 LRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNIT 636

Query: 667 AGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKET 726
           AG       +++  +++E  L      +   D    ++   L+RNLSRN   ++E++ + 
Sbjct: 637 AGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKV 696

Query: 727 LPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAI-SAGD 785
           +  L+  +P +V       E   +    LNN++  S   ARDLL   G++K++ I    D
Sbjct: 697 VSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRD 756

Query: 786 AYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV 824
           +  S K+S+AAS LL +LW + +LH  ++   ++K DF+
Sbjct: 757 SPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFL 795


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score =  265 bits (676), Expect = 2e-70
 Identities = 178/538 (33%), Positives = 278/538 (51%), Gaps = 33/538 (6%)

Query: 321 VGQAAAGGSGNL--LTERSTFTDSQLGNADM-EMTLERAVSMLEADHMLPSRISAAATFI 377
           + Q   G  G+L  L  RS   DS        +  L   ++ML   H +    + AA ++
Sbjct: 325 LAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLR--HPVDPVKANAAAYL 382

Query: 378 QHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDNKLEVAEL 436
           QH CF+    ++RV QLRG+  L+ LL     +V+R  CGALRNL +  D DNK  + + 
Sbjct: 383 QHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDC 442

Query: 437 NGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 496
            GVP L+++L+  RD E ++ +TG LWNLSS + LK ++I   L TLT  +I+P SGW  
Sbjct: 443 GGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWER 502

Query: 497 --GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQ 554
              +  K        +F N +GCLRN+SS GA+ R+ +R C+GL+D+L+H ++  +    
Sbjct: 503 EPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKD 562

Query: 555 PDDKATENCVCILHNLSYQLEAELP--EKYSQ---NIYIQNRNIQTDNNKSIGCFGSRSR 609
            D+K+ ENCVCI+ NLSY +  E+P  ++Y +            Q        CFG +  
Sbjct: 563 TDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKA 622

Query: 610 K------------VKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEA 657
           K            +   +  + +P+     KG E L+   V+R+YLSL+ +S    T EA
Sbjct: 623 KEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEA 682

Query: 658 SLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLS 717
           + GALQNL+AG+    T +  T V+KE GL    ++L      V +     LRNLS +  
Sbjct: 683 AAGALQNLSAGNWMWATYIRAT-VRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRR 741

Query: 718 LQNEIAKETLPDLVSIIPDTV----PSTDLLIETTASACYTLNNIIQNSYQNARDLLNTG 773
            ++ I    + +LV  + +      P   L  +T  +   T++ I+ +S  NAR LL   
Sbjct: 742 NKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQAR 801

Query: 774 GIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVN-SRTAK 830
           G+  ++A+ A     S + +KAAS +L ++W++ EL    +K  + K  F + + TAK
Sbjct: 802 GVPALVALVASS--QSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAK 857


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 518 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 577

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 578 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 636

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 637 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 696

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 697 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 755

Query: 833 HSLKD 837
           HS  D
Sbjct: 756 HSYDD 760


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 518 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 577

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 578 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 636

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 637 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 696

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 697 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 755

Query: 833 HSLKD 837
           HS  D
Sbjct: 756 HSYDD 760


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 518 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 577

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 578 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 636

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 637 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 696

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 697 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 755

Query: 833 HSLKD 837
           HS  D
Sbjct: 756 HSYDD 760


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 518 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 577

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 578 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 636

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 637 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 696

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 697 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 755

Query: 833 HSLKD 837
           HS  D
Sbjct: 756 HSYDD 760


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 518 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 577

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 578 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 636

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 637 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 696

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 697 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 755

Query: 833 HSLKD 837
           HS  D
Sbjct: 756 HSYDD 760


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 503

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 504 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 562

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 563 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 618

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 619 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 678

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 679 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 737

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 738 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 797

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 798 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 856

Query: 833 HSLKD 837
           HS  D
Sbjct: 857 HSYDD 861


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 503

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 504 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 562

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 563 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 618

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 619 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 678

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 679 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 737

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 738 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 797

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 798 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 856

Query: 833 HSLKD 837
           HS  D
Sbjct: 857 HSYDD 861


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 503

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 504 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 562

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 563 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 618

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 619 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 678

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 679 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 737

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 738 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 797

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 798 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 856

Query: 833 HSLKD 837
           HS  D
Sbjct: 857 HSYDD 861


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 503

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 504 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 562

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 563 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 618

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 619 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 678

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 679 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 737

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 738 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 797

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 798 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 856

Query: 833 HSLKD 837
           HS  D
Sbjct: 857 HSYDD 861


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score =  263 bits (672), Expect = 5e-70
 Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 25/485 (5%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 503

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 504 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 562

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 563 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 618

Query: 604 FGSRSRKVKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEAS 658
           FG++  K K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS
Sbjct: 619 FGAKKGKGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEAS 678

Query: 659 LGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSL 718
            GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL+ +   
Sbjct: 679 AGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARN 737

Query: 719 QNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQ 776
           +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+
Sbjct: 738 KELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIE 797

Query: 777 KIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAY 832
           K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ 
Sbjct: 798 KLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSS 856

Query: 833 HSLKD 837
           HS  D
Sbjct: 857 HSYDD 861


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score =  256 bits (655), Expect = 5e-68
 Identities = 165/491 (33%), Positives = 265/491 (53%), Gaps = 31/491 (6%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRK------VKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRN 652
           FG++  K       K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S   
Sbjct: 518 FGAKKGKDEWFSRGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTP 577

Query: 653 YTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNL 712
              EAS GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL
Sbjct: 578 AILEASAGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNL 636

Query: 713 SRNLSLQNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLL 770
           + +   +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L 
Sbjct: 637 AVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLR 696

Query: 771 NTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NS 826
            T GI+K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+
Sbjct: 697 ETQGIEKLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNA 755

Query: 827 RTAKAYHSLKD 837
             +++ HS  D
Sbjct: 756 SRSQSSHSYDD 766


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score =  256 bits (655), Expect = 5e-68
 Identities = 165/491 (33%), Positives = 265/491 (53%), Gaps = 31/491 (6%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 402

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 403 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 461

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 462 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 517

Query: 604 FGSRSRK------VKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRN 652
           FG++  K       K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S   
Sbjct: 518 FGAKKGKDEWFSRGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTP 577

Query: 653 YTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNL 712
              EAS GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL
Sbjct: 578 AILEASAGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNL 636

Query: 713 SRNLSLQNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLL 770
           + +   +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L 
Sbjct: 637 AVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLR 696

Query: 771 NTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NS 826
            T GI+K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+
Sbjct: 697 ETQGIEKLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNA 755

Query: 827 RTAKAYHSLKD 837
             +++ HS  D
Sbjct: 756 SRSQSSHSYDD 766


>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
          Length = 968

 Score =  256 bits (655), Expect = 5e-68
 Identities = 165/491 (33%), Positives = 265/491 (53%), Gaps = 31/491 (6%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIII 489
           K+ +   +GVP L+++L++ RD++  + ITG LWNLSS+D +K  ++  AL  LT+ +II
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVII 503

Query: 490 PFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV 546
           P SGW   P  D  K   +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V
Sbjct: 504 PHSGWEREPNEDC-KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIV 562

Query: 547 RGTIADYQPDDKATENCVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGC 603
           +  I     D K  ENCVC+L NLSYQ+  E+P  E+Y +       N+  +    +  C
Sbjct: 563 QAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASC 618

Query: 604 FGSRSRK------VKEQYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRN 652
           FG++  K       K+  +D     V  P+  S  +G E L+   V+R+Y+SL+ +S   
Sbjct: 619 FGAKKGKDEWFSRGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTP 678

Query: 653 YTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNL 712
              EAS GA+QNL AG       + ++ +++E  L     +L      V K A   LRNL
Sbjct: 679 AILEASAGAIQNLCAGRWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNL 737

Query: 713 SRNLSLQNEIAKETLPDLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLL 770
           + +   +  I K  +P+LV  +P      S +   +T  S   T+N +I  + + A+ L 
Sbjct: 738 AVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLR 797

Query: 771 NTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NS 826
            T GI+K++ I+      S K  +AA+++L ++W + EL    +K  +KK+DF     N+
Sbjct: 798 ETQGIEKLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNA 856

Query: 827 RTAKAYHSLKD 837
             +++ HS  D
Sbjct: 857 SRSQSSHSYDD 867


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (2%)

Query: 394 LRGILK-LLQLLKVQNEDVQRAVCGALRNLVFE-DNDNKLEVAELNGVPRLLQVLKQTRD 451
           ++G ++ L+  LK ++ED+Q+ +   LRNL +  D ++K  + E+  V  L++   + + 
Sbjct: 522 MKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKK 581

Query: 452 LETKKQITGLLWNLSSN 468
             T K +   LWNLS++
Sbjct: 582 ESTLKSVLSALWNLSAH 598


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (2%)

Query: 394 LRGILK-LLQLLKVQNEDVQRAVCGALRNLVFE-DNDNKLEVAELNGVPRLLQVLKQTRD 451
           ++G ++ L+  LK ++ED+Q+ +   LRNL +  D ++K  + E+  V  L++   + + 
Sbjct: 522 MKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKK 581

Query: 452 LETKKQITGLLWNLSSN 468
             T K +   LWNLS++
Sbjct: 582 ESTLKSVLSALWNLSAH 598


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (2%)

Query: 394 LRGILK-LLQLLKVQNEDVQRAVCGALRNLVFE-DNDNKLEVAELNGVPRLLQVLKQTRD 451
           ++G ++ L+  LK ++ED+Q+ +   LRNL +  D ++K  + E+  V  L++   + + 
Sbjct: 522 MKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKK 581

Query: 452 LETKKQITGLLWNLSSN 468
             T K +   LWNLS++
Sbjct: 582 ESTLKSVLSALWNLSAH 598


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%)

Query: 395 RGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLET 454
           +GI +L+QLLK  NE+V+ A   AL NL   +  N    AE +G+  L+ +L   RD   
Sbjct: 356 QGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAI 415

Query: 455 KKQITGLLWNLSSNDKLK 472
               T +L N++  + L+
Sbjct: 416 ANAAT-VLTNMAMQEPLR 432



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 403 LLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLL 462
           +L    E++    C A+     +  +NK  + EL  V  L ++L    D   ++  T + 
Sbjct: 33  MLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTH-EDKIVRRNATMIF 91

Query: 463 WNLSSNDKLKNLM 475
             L+SN+ +K L+
Sbjct: 92  GILASNNDVKKLL 104


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 16/163 (9%)

Query: 616 QDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTS 675
           Q  P P E     GV  L      R  L+L+ KS   + Q+ +L  L N          S
Sbjct: 371 QKRPFPYEIDEILGVRDL------RKVLALLQKSDDPFIQQVALLTLSNNAN------YS 418

Query: 676 VAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEI---AKETLPDLV- 731
             Q  ++K  GL     M++  DP +K+ A+  + NLS N   Q  +     + + D++ 
Sbjct: 419 CNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMA 478

Query: 732 SIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGG 774
           S +   V    L   T  +      +++ NS  N   LL+ GG
Sbjct: 479 SNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGG 521


>gi|29540562 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 16/163 (9%)

Query: 616 QDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTS 675
           Q  P P E     GV  L      R  L+L+ KS   + Q+ +L  L N          S
Sbjct: 371 QKRPFPYEIDEILGVRDL------RKVLALLQKSDDPFIQQVALLTLSNNAN------YS 418

Query: 676 VAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEI---AKETLPDLV- 731
             Q  ++K  GL     M++  DP +K+ A+  + NLS N   Q  +     + + D++ 
Sbjct: 419 CNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMA 478

Query: 732 SIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGG 774
           S +   V    L   T  +      +++ NS  N   LL+ GG
Sbjct: 479 SNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGG 521


>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 37/159 (23%), Positives = 72/159 (45%), Gaps = 16/159 (10%)

Query: 622 EEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVV 681
           +++++P   + +     ++  L L+  S + Y  EA+L AL N  A       +  + ++
Sbjct: 106 QKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAA------YAFNRDII 159

Query: 682 QKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQ-------NEIAKETLPDLVSII 734
           +   GL    K+L+  DP VK+ A+ +L NLS N   Q       N++  +T   + S +
Sbjct: 160 RDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDT---ITSRL 216

Query: 735 PDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTG 773
             +V    L + T  +      +++ NS  +   L + G
Sbjct: 217 NSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAG 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,089,100
Number of Sequences: 37866
Number of extensions: 1301036
Number of successful extensions: 3969
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3751
Number of HSP's gapped (non-prelim): 97
length of query: 837
length of database: 18,247,518
effective HSP length: 111
effective length of query: 726
effective length of database: 14,044,392
effective search space: 10196228592
effective search space used: 10196228592
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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