Guide to the Human Genome
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Search of human proteins with 148612821

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148612821 tetratricopeptide repeat domain 29 [Homo sapiens]
         (475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148612821 tetratricopeptide repeat domain 29 [Homo sapiens]        955   0.0  
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         54   3e-07
gi|164519122 LGN protein [Homo sapiens]                                50   4e-06
gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg...    42   0.001
gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg...    42   0.001
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    35   0.15 
gi|98961156 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|98961154 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|98961152 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|98961150 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|98961148 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|98961143 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|98961146 tetratricopeptide repeat domain 23 [Homo sapiens]          35   0.15 
gi|46358428 selective LIM binding factor homolog [Homo sapiens]        34   0.25 
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ...    34   0.25 
gi|83415184 transmembrane and tetratricopeptide repeat containin...    34   0.25 
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    34   0.33 
gi|187761311 heme oxygenase (decyclizing) 2 [Homo sapiens]             34   0.33 
gi|187761309 heme oxygenase (decyclizing) 2 [Homo sapiens]             34   0.33 
gi|187761307 heme oxygenase (decyclizing) 2 [Homo sapiens]             34   0.33 
gi|8051608 heme oxygenase (decyclizing) 2 [Homo sapiens]               34   0.33 
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]        34   0.33 
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ...    34   0.33 
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom...    33   0.74 
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]       33   0.74 
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]       33   0.74 
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap...    32   1.3  
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap...    32   1.3  
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap...    32   1.3  
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap...    32   1.3  

>gi|148612821 tetratricopeptide repeat domain 29 [Homo sapiens]
          Length = 475

 Score =  955 bits (2468), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAY 60
           MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAY
Sbjct: 1   MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAY 60

Query: 61  RNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAARVRSLFWLQKPLEEQPDKLDYL 120
           RNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAARVRSLFWLQKPLEEQPDKLDYL
Sbjct: 61  RNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAARVRSLFWLQKPLEEQPDKLDYL 120

Query: 121 YHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKK 180
           YHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKK
Sbjct: 121 YHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKK 180

Query: 181 EAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLL 240
           EAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLL
Sbjct: 181 EAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLL 240

Query: 241 SDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTY 300
           SDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTY
Sbjct: 241 SDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTY 300

Query: 301 CKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTML 360
           CKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTML
Sbjct: 301 CKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTML 360

Query: 361 GDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESAD 420
           GDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESAD
Sbjct: 361 GDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESAD 420

Query: 421 LTSLNYLLSWKESRGNIEPDPVTEEFRGSTVEAVSQNSERLEELSRFPGDQKNET 475
           LTSLNYLLSWKESRGNIEPDPVTEEFRGSTVEAVSQNSERLEELSRFPGDQKNET
Sbjct: 421 LTSLNYLLSWKESRGNIEPDPVTEEFRGSTVEAVSQNSERLEELSRFPGDQKNET 475


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 53/241 (21%), Positives = 104/241 (43%), Gaps = 16/241 (6%)

Query: 162  FYERCFKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDET 221
            +YE+   +AQ   ++  + +A+A+  +G  +   G L +A   +E      +  +   E 
Sbjct: 899  YYEQYLSVAQ--SLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFE------KRLVVAHEL 950

Query: 222  GRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLG 281
            G + N        + Y  L     +   Y+QAI  L +   IA++  D+ +E++A+  LG
Sbjct: 951  GEAFNKA------QAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLG 1004

Query: 282  LAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFV 341
              +    EY+TAL       +I+ + ++    GR Y  +    +S G    A+ Y ++ +
Sbjct: 1005 GVYQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHL 1064

Query: 342  KIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYG 401
             IA           + + LG  ++    Y++A    Q+      +L      DE K+ +G
Sbjct: 1065 SIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRRE--DEAKIRHG 1122

Query: 402  I 402
            +
Sbjct: 1123 L 1123



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 60/249 (24%), Positives = 105/249 (42%), Gaps = 20/249 (8%)

Query: 163 YERCFKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETG 222
           +++C  +A+  K +    EA    +MG +Y   G    A + +E   ++ +    K E  
Sbjct: 337 HKQCVLLAKQSKDELS--EARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEA 394

Query: 223 RSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGL 282
           R+ + L        YR   DK +    Y           E+A+E  +K +E  A  Y GL
Sbjct: 395 RAYSNLGSAY---HYRRNFDKAMSYHNY---------VLELAQELMEKAIEMRA--YAGL 440

Query: 283 AHLAA--EEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKF 340
            H A   ++ E A    +    I+ DL D  + GR    +  + Q +G+   A+K  K  
Sbjct: 441 GHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTH 500

Query: 341 VKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHY 400
           + IA+         RA   +G+ YN  G Y++A +  +Q    ++E+       +   H 
Sbjct: 501 LCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDR--ASQASTHG 558

Query: 401 GIAKAHQMM 409
            +A A+Q +
Sbjct: 559 NLAVAYQAL 567



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 77/335 (22%), Positives = 127/335 (37%), Gaps = 64/335 (19%)

Query: 119 YLYHYLTRAEDAERKESFEDVHNNL-YALACYFNNSEDKWVRNHFYERCFKIAQLIKIDC 177
           Y   YL  A D +  E    V +NL YA  C  N  E       +YE+   +A+   +  
Sbjct: 616 YYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAV----KYYEQDLALAK--DLHD 669

Query: 178 GKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTY 237
              +A+A+ ++GL ++      +A E  +    L Q          SLN    ++  R  
Sbjct: 670 KLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQ----------SLN--NSQAKFRAL 717

Query: 238 RLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVL 297
             L D  +  K+   AIK   +   +A +  D+++EA A   LG A+   ++Y+ AL   
Sbjct: 718 GNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYH 777

Query: 298 DTYCKISTDLDDDLSLGRGYEAIAKVLQSQGE---------------------------- 329
               ++  +L D     R +  +A V  + G+                            
Sbjct: 778 TQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVY 837

Query: 330 ------------MTEAIKYLKKFVKIAR---NNFQSLDLVRASTMLGDIYNEKGYYNKAS 374
                       M EAI Y ++ + + +    N   LD  RA   LGD Y   G Y +A 
Sbjct: 838 GNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAI 897

Query: 375 ECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMM 409
           + ++Q       L  M   D+ K + G+   H+ M
Sbjct: 898 KYYEQYLSVAQSLNRM--QDQAKAYRGLGNGHRAM 930



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 66/298 (22%), Positives = 120/298 (40%), Gaps = 63/298 (21%)

Query: 163 YERCFKIAQLIKIDCGKK--EAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDE 220
           +E+  KIA+    D G K  EA A+ ++G  Y       +A  ++    +L Q  + K  
Sbjct: 377 HEQHLKIAK----DLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEK-- 430

Query: 221 TGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYL 280
              ++ + A   L    R + D     + ++Q + I       A++  D+  E  AS  L
Sbjct: 431 ---AIEMRAYAGLGHAARCMQDLERAKQYHEQQLGI-------AEDLKDRAAEGRASSNL 480

Query: 281 GLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKF 340
           G+ H    +Y+TAL +  T+  I+ +L D  + GR Y  +     + G   +A+KY ++ 
Sbjct: 481 GIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQE 540

Query: 341 VKIARN----------------NFQSLDL------------------------VRASTML 360
           ++I+                   +Q+L                           RA + L
Sbjct: 541 LQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNL 600

Query: 361 GDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIES 418
           G+ +  +G Y +A+  ++Q      +L  M    E KV + +  AH  +    NY E+
Sbjct: 601 GNFHCSRGEYVQAAPYYEQYLRLAPDLQDME--GEGKVCHNLGYAHYCL---GNYQEA 653



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 77/332 (23%), Positives = 129/332 (38%), Gaps = 29/332 (8%)

Query: 51  GLSKEEVAAYRN-----SYKKNICVDMLRDGYHKSFTELFA-LMERWDALREAARVRSLF 104
           G  +EE  AY N      Y++N    M    YH    EL   LME+   +R  A +    
Sbjct: 388 GNKREEARAYSNLGSAYHYRRNFDKAM---SYHNYVLELAQELMEKAIEMRAYAGLGHAA 444

Query: 105 WLQKPLEEQPDKLDYLYHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYE 164
              + LE       Y    L  AED + + +     +NL  +        D  ++ H   
Sbjct: 445 RCMQDLERAKQ---YHEQQLGIAEDLKDRAAEGRASSNL-GIIHQMKGDYDTALKLHKTH 500

Query: 165 RCFKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRS 224
            C  IAQ  ++     +  A+ +MG  Y   G   +A +++    Q++      +   R+
Sbjct: 501 LC--IAQ--ELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISM-----EVNDRA 551

Query: 225 LNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAH 284
                  +L   Y+ L       + Y+  + I       A+E  D + EA A   LG  H
Sbjct: 552 SQASTHGNLAVAYQALGAHDRALQHYQNHLNI-------ARELRDIQSEARALSNLGNFH 604

Query: 285 LAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIA 344
            +  EY  A    + Y +++ DL D    G+    +       G   EA+KY ++ + +A
Sbjct: 605 CSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALA 664

Query: 345 RNNFQSLDLVRASTMLGDIYNEKGYYNKASEC 376
           ++    L   +A   LG  +     ++KA EC
Sbjct: 665 KDLHDKLSQAKAYCNLGLAFKALLNFSKAEEC 696



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 47/230 (20%), Positives = 100/230 (43%), Gaps = 13/230 (5%)

Query: 181  EAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLL 240
            E  AH H+  +Y   G+   A + YE   QL  G+  KD    SL      ++  T   +
Sbjct: 793  ECRAHGHLAAVYMALGKYTMAFKCYE--EQLDLGQKLKDP---SLEAQVYGNMGITKMNM 847

Query: 241  SDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASY-YLGLAHLAAEEYETALTVLDT 299
            +        ++Q + +L + S     G++  ++   +Y  LG  + A  +YE A+   + 
Sbjct: 848  NVMEEAIGYFEQQLAMLQQLS-----GNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQ 902

Query: 300  YCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTM 359
            Y  ++  L+      + Y  +    ++ G + +A+   +K + +A    ++ +  +A   
Sbjct: 903  YLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGE 962

Query: 360  LGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMM 409
            LG ++++ G Y +A  C ++  +   ++    L  E+    G+   +Q M
Sbjct: 963  LGSLHSQLGNYEQAISCLERQLNIARDMKDRAL--ESDAACGLGGVYQQM 1010



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 63/293 (21%), Positives = 121/293 (41%), Gaps = 23/293 (7%)

Query: 133 KESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY 192
           + S    H NL A+A     + D+ +++  Y+    IA+ ++    + EA A  ++G  +
Sbjct: 550 RASQASTHGNL-AVAYQALGAHDRALQH--YQNHLNIARELRDI--QSEARALSNLGNFH 604

Query: 193 EEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQ 252
              G+ ++AA +YE + +L       +  G+      C +L   +  L +       Y++
Sbjct: 605 CSRGEYVQAAPYYEQYLRLAPDLQDMEGEGK-----VCHNLGYAHYCLGN-------YQE 652

Query: 253 AIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLS 312
           A+K   +   +AK+  DK  +A+A   LGLA  A   +  A         ++  L++  +
Sbjct: 653 AVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQA 712

Query: 313 LGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNK 372
             R    +  +   + ++  AIK+ ++ + +A           A   LG  Y     Y+K
Sbjct: 713 KFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDK 772

Query: 373 ASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMM----LTVNNYIESADL 421
           A     Q  +   EL  +P   E + H  +A  +  +    +    Y E  DL
Sbjct: 773 ALGYHTQELEVYQELSDLP--GECRAHGHLAAVYMALGKYTMAFKCYEEQLDL 823



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/175 (21%), Positives = 73/175 (41%), Gaps = 2/175 (1%)

Query: 235 RTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETAL 294
           R +  L         Y++A+        +A +  D++  + A   LG  + A  +Y  AL
Sbjct: 275 RAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNAL 334

Query: 295 TVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLV 354
                   ++    D+LS  R    +  V  + G+   A++  ++ +KIA++     +  
Sbjct: 335 ASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEA 394

Query: 355 RASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMM 409
           RA + LG  Y+ +  ++KA        +   ELM   +  E + + G+  A + M
Sbjct: 395 RAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAI--EMRAYAGLGHAARCM 447



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 28/118 (23%), Positives = 49/118 (41%)

Query: 262 EIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIA 321
           ++AK   D+  E  A   LG A  +   Y  ALT       ++  L D  +      ++ 
Sbjct: 262 DVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLG 321

Query: 322 KVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQ 379
            V  + G+   A+   K+ V +A+ +   L   R    +G +Y   G +  A +C +Q
Sbjct: 322 HVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQ 379



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 24/166 (14%)

Query: 181  EAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLL 240
            +  A+ ++GL YE  G    A  + E    L+      D   ++++     SL RT+  L
Sbjct: 1036 QGRAYGNLGLTYESLGTFERAVVYQE--QHLSIAAQMNDLAAKTVSY---SSLGRTHHAL 1090

Query: 241  SDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETA------L 294
             +       Y QA+  L +   +A++   ++ EA+  + LGL+  A+   E A       
Sbjct: 1091 QN-------YSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRA 1143

Query: 295  TVLDTYCKISTDLDDDLSLG------RGYEAIAKVLQSQGEMTEAI 334
            + L    +    L  D  L         Y+A+ +VL S G   EA+
Sbjct: 1144 SALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEAL 1189


>gi|164519122 LGN protein [Homo sapiens]
          Length = 684

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 19/167 (11%)

Query: 172 LIKIDCGKKEAE--AHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLA 229
           LI  + G K AE  A+ ++G  Y   G+   A+E+Y+    L   R  KD   R++   +
Sbjct: 230 LIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKK--TLLLARQLKD---RAVEAQS 284

Query: 230 CESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEE 289
           C SL  TY LL D       Y++AI   +K   IA+E +D+  E  A + LG A+ A   
Sbjct: 285 CYSLGNTYTLLQD-------YEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGN 337

Query: 290 YETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKY 336
           ++ A+   + + +IS ++ D     +  E  A++  S  +M   + Y
Sbjct: 338 HDQAMHFAEKHLEISREVGD-----KSGELTARLNLSDLQMVLGLSY 379



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 26/111 (23%), Positives = 57/111 (51%)

Query: 235 RTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETAL 294
           R Y  L +  +   E++ A +   K   +A++  D+ +EA++ Y LG  +   ++YE A+
Sbjct: 243 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAI 302

Query: 295 TVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIAR 345
                +  I+ +L+D +  GR   ++     + G   +A+ + +K ++I+R
Sbjct: 303 DYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISR 353



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/191 (23%), Positives = 82/191 (42%), Gaps = 9/191 (4%)

Query: 263 IAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAK 322
           IAKE  DK  E  A   LG A++   E+ETA         ++  L D     +   ++  
Sbjct: 231 IAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGN 290

Query: 323 VLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKAS-------E 375
                 +  +AI Y  K + IA+     +   RA   LG+ Y   G +++A        E
Sbjct: 291 TYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLE 350

Query: 376 CFQQAFDTTVELMSMPLMDETKVHYGIA-KAHQMMLTVNNYIESADLTSLNYLLSWKESR 434
             ++  D + EL +   + + ++  G++   +  +++ N  I+S+ L  +   L  + S 
Sbjct: 351 ISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSS-LNGVRPKLGRRHSM 409

Query: 435 GNIEPDPVTEE 445
            N+E   +T E
Sbjct: 410 ENMELMKLTPE 420



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 30/191 (15%)

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGS 268
           H LT  R   D+ G +    A  +L  T ++L +       + +AI    +  +I++E +
Sbjct: 87  HDLTLARTIGDQLGEAK---ASGNLGNTLKVLGN-------FDEAIVCCQRHLDISRELN 136

Query: 269 DKKMEAEASYYLGLAHLAA----------------EEYETAL-TVLDTY---CKISTDLD 308
           DK  EA A Y LG  + A                 EE   AL   +D Y     + T L 
Sbjct: 137 DKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALG 196

Query: 309 DDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKG 368
           D  + GR +  +       G   +A+   ++ + IA+         RA + LG+ Y   G
Sbjct: 197 DRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLG 256

Query: 369 YYNKASECFQQ 379
            +  ASE +++
Sbjct: 257 EFETASEYYKK 267



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 27/130 (20%), Positives = 54/130 (41%), Gaps = 2/130 (1%)

Query: 239 LLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLD 298
           L  +++ ++ + +  +     A ++  E  D K  +     LG A+    +Y  AL    
Sbjct: 29  LEGERLCKSGDCRAGVSFFEAAVQVGTE--DLKTLSAIYSQLGNAYFYLHDYAKALEYHH 86

Query: 299 TYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRAST 358
               ++  + D L   +    +   L+  G   EAI   ++ + I+R     +   RA  
Sbjct: 87  HDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALY 146

Query: 359 MLGDIYNEKG 368
            LG++Y+ KG
Sbjct: 147 NLGNVYHAKG 156



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 24/105 (22%), Positives = 39/105 (37%)

Query: 269 DKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQG 328
           D+  +  A   LG  H     +  A+   +    I+ +  D  +  R Y  +       G
Sbjct: 197 DRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLG 256

Query: 329 EMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKA 373
           E   A +Y KK + +AR         ++   LG+ Y     Y KA
Sbjct: 257 EFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKA 301


>gi|224548927 G-protein signaling modulator 1 (AGS3-like, C.
           elegans) isoform a [Homo sapiens]
          Length = 675

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 26/111 (23%), Positives = 54/111 (48%)

Query: 235 RTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETAL 294
           R Y  L +  +    +  A +   K  +++++  D+ +EA+A Y LG  +   ++YE A 
Sbjct: 250 RAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAA 309

Query: 295 TVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIAR 345
                +  I+ +L D +  GR   ++     S G   +A+ + KK ++I++
Sbjct: 310 EYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQ 360



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 54/238 (22%), Positives = 92/238 (38%), Gaps = 40/238 (16%)

Query: 208 FHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENK---EYKQAIKILIKASE-- 262
           + QL     +  E GR+L     + LL   R + D+M E K        +K+L +  E  
Sbjct: 69  YSQLGNAYFYLKEHGRALEYHKHDLLLA--RTIGDRMGEAKASGNLGNTLKVLGRFDEAA 126

Query: 263 --------IAKEGSDKKMEAEASYYLG-------------LAHLAAEEYETALTVLDTYC 301
                   IA+E  DK  EA A Y +G              A+   +       V +T C
Sbjct: 127 VCCQRHLSIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAANATQDPGHLPPDVRETLC 186

Query: 302 KIST----------DLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSL 351
           K S           +L D  + GR Y  +       G  TEA  + K+ + IA+      
Sbjct: 187 KASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKA 246

Query: 352 DLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMM 409
              RA + LG+ +   G ++ A+E +++    + +L    +  E +  Y +   + ++
Sbjct: 247 AERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAV--EAQACYSLGNTYTLL 302



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 7/126 (5%)

Query: 257 LIKASE-------IAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDD 309
           L KASE       + KE  D+  +  A   LG  H     +  A T       I+ +  D
Sbjct: 185 LCKASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGD 244

Query: 310 DLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGY 369
             +  R Y  +       G    A +Y KK ++++R         +A   LG+ Y     
Sbjct: 245 KAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQD 304

Query: 370 YNKASE 375
           Y +A+E
Sbjct: 305 YERAAE 310



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 26/106 (24%), Positives = 41/106 (38%)

Query: 263 IAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAK 322
           IAKE  DK  E  A   LG AH+    ++ A        ++S  L D     +   ++  
Sbjct: 238 IAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGN 297

Query: 323 VLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKG 368
                 +   A +Y  + + IA+     +   RA   LG+ Y   G
Sbjct: 298 TYTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMG 343


>gi|224548925 G-protein signaling modulator 1 (AGS3-like, C.
           elegans) isoform b [Homo sapiens]
          Length = 457

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 26/111 (23%), Positives = 54/111 (48%)

Query: 235 RTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETAL 294
           R Y  L +  +    +  A +   K  +++++  D+ +EA+A Y LG  +   ++YE A 
Sbjct: 250 RAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAA 309

Query: 295 TVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIAR 345
                +  I+ +L D +  GR   ++     S G   +A+ + KK ++I++
Sbjct: 310 EYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQ 360



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 54/238 (22%), Positives = 92/238 (38%), Gaps = 40/238 (16%)

Query: 208 FHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENK---EYKQAIKILIKASE-- 262
           + QL     +  E GR+L     + LL   R + D+M E K        +K+L +  E  
Sbjct: 69  YSQLGNAYFYLKEHGRALEYHKHDLLLA--RTIGDRMGEAKASGNLGNTLKVLGRFDEAA 126

Query: 263 --------IAKEGSDKKMEAEASYYLG-------------LAHLAAEEYETALTVLDTYC 301
                   IA+E  DK  EA A Y +G              A+   +       V +T C
Sbjct: 127 VCCQRHLSIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAANATQDPGHLPPDVRETLC 186

Query: 302 KIST----------DLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSL 351
           K S           +L D  + GR Y  +       G  TEA  + K+ + IA+      
Sbjct: 187 KASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKA 246

Query: 352 DLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMM 409
              RA + LG+ +   G ++ A+E +++    + +L    +  E +  Y +   + ++
Sbjct: 247 AERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAV--EAQACYSLGNTYTLL 302



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 7/126 (5%)

Query: 257 LIKASE-------IAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDD 309
           L KASE       + KE  D+  +  A   LG  H     +  A T       I+ +  D
Sbjct: 185 LCKASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGD 244

Query: 310 DLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGY 369
             +  R Y  +       G    A +Y KK ++++R         +A   LG+ Y     
Sbjct: 245 KAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQD 304

Query: 370 YNKASE 375
           Y +A+E
Sbjct: 305 YERAAE 310



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 26/106 (24%), Positives = 41/106 (38%)

Query: 263 IAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAK 322
           IAKE  DK  E  A   LG AH+    ++ A        ++S  L D     +   ++  
Sbjct: 238 IAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGN 297

Query: 323 VLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKG 368
                 +   A +Y  + + IA+     +   RA   LG+ Y   G
Sbjct: 298 TYTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMG 343


>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 52/223 (23%), Positives = 89/223 (39%), Gaps = 39/223 (17%)

Query: 167  FKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLN 226
            F I Q+ ++D G  E    M   L+Y          E+++   ++  G  W         
Sbjct: 1104 FTIYQIAEMDKGLSELSP-MQQALIYS-------FCENHDKAIEVLDGISWN-------- 1147

Query: 227  LLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDK-----KMEAEASYYLG 281
                 + +    LL+   ++ K  K+A+++L KA + A   SDK      + A+  Y LG
Sbjct: 1148 ----RAEMTMCALLAKVQMKAKRTKEAVEVLKKALD-ASSHSDKGPDATTISADCLYNLG 1202

Query: 282  LAHLAAEEYETA--LTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKK 339
            L ++     +    L + D    IS D +  ++         K+ + Q  +T+    L  
Sbjct: 1203 LCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLL- 1261

Query: 340  FVKIARNNFQSLDLVRASTML--GDIYNEKGYYNKASECFQQA 380
                      + + V+ +T L  G IY E G Y  A E F+QA
Sbjct: 1262 --------LDATETVKLNTFLNRGLIYVELGQYGFALEDFKQA 1296


>gi|98961156 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|98961154 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|98961152 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|98961150 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|98961148 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|98961143 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|98961146 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 150 FNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLY-EEDGQLLEAAEHYEAF 208
           ++NS +     H   RC  + ++   D   K AEAH+++   Y +  G  L+A +H E  
Sbjct: 55  YSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKA 114

Query: 209 HQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKE 266
            Q+    I       S N    +  +  +  +   +L  +++K+A + L KA  ++KE
Sbjct: 115 RQILANSI---VPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKE 169


>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
          Length = 1749

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 47/218 (21%), Positives = 89/218 (40%), Gaps = 30/218 (13%)

Query: 13   KLTALARQKLPCSSRKIPRS---QLIKEKD---DIDHYLEVNFKGLSKEEVAAYRNSYKK 66
            K   LAR   P    K+  +    L+++K     I+HY+E     +   E A     +KK
Sbjct: 840  KAVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCS-IKAIEAALGARQWKK 898

Query: 67   NICVDMLRDG-----YHKSFTELFALMERWDALRE----AARVRSLF--WLQKPLEEQPD 115
             I +  L+D      Y+    + +A ++ ++   E      R +     + Q    EQ  
Sbjct: 899  AIYILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAH 958

Query: 116  KL--------DYLYHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCF 167
            KL        D    Y+T+A++ E++  + +    LY      + +   + ++  Y+   
Sbjct: 959  KLAMKCMRPEDVSVLYITQAQEMEKQGKYREAER-LYVTVQEPDLAITMYKKHKLYDDMI 1017

Query: 168  KIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHY 205
            ++      D     ++ H+H+G   E +G+L EA  HY
Sbjct: 1018 RLVGKHHPDL---LSDTHLHLGKELEAEGRLQEAEYHY 1052


>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
           sapiens]
          Length = 807

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 20/158 (12%)

Query: 231 ESLLRTYRLLSDKMLEN--KEYKQAIKILIKASEIAKEGSD--KKMEAEASYYL----GL 282
           E L   Y L+   + +   + +   ++IL     I +  +D  K ++ + S  L    G 
Sbjct: 145 EELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGT 204

Query: 283 AHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVK 342
            +  +E+Y TA          S +L+ +  +   Y+ +      +G + EAI+  K+ +K
Sbjct: 205 LYFISEDYATAHEDFQQ----SLELNKNQPIAMLYKGLT--FFHRGLLKEAIESFKEALK 258

Query: 343 IARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
                 Q +D + A   LG  Y E G +  A+E FQ+A
Sbjct: 259 ------QKVDFIDAYKSLGQAYRELGNFEAATESFQKA 290


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 69/344 (20%), Positives = 128/344 (37%), Gaps = 58/344 (16%)

Query: 43  HYLEVNF---KGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAAR 99
           HY   NF   +G +KE +  YR + K       L   +  +   L  L       R+ A 
Sbjct: 378 HYNYANFLKDQGRNKEAIYHYRTALK-------LYPRHASALNNLGTLT------RDTAE 424

Query: 100 VRSLFWLQKPLEEQPDKLDYLYHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVR 159
            +  +  Q+ L+  P     L++     +  E+KE    +  +       F ++      
Sbjct: 425 AKMYY--QRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLAS 482

Query: 160 NHFYERCFKIAQLIK---IDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRI 216
               +  FK A+ I    I      ++ H + G+   + G   +A  HY+   +L+    
Sbjct: 483 LLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPS-- 540

Query: 217 WKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEA 276
                    + +A  +L R YR L +  +  + YK+A+++  KA  ++            
Sbjct: 541 ---------HHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSP----------- 580

Query: 277 SYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKY 336
              LG  +     YE AL +      +      +L L     A+A+VL   G+  EA K 
Sbjct: 581 ---LGALYYNTGRYEEALQIYQEAAALQPS-QRELRL-----ALAQVLAVMGQTKEAEKM 631

Query: 337 LKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
               V       +    +    +L  IY+++  ++KA +   +A
Sbjct: 632 TNHIVS------EETGCLECYRLLSAIYSKQENHDKALDAIDKA 669


>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 52/223 (23%), Positives = 89/223 (39%), Gaps = 39/223 (17%)

Query: 167  FKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLN 226
            F I Q+ ++D G  E    M   L+Y          E+++   ++  G  W         
Sbjct: 1104 FTIYQIAEMDKGLSELSP-MQQALIYS-------FCENHDKAIEVLDGISWN-------- 1147

Query: 227  LLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDK-----KMEAEASYYLG 281
                 + +    LL+   ++ K  K+A+++L KA + A   SDK      + A+  Y LG
Sbjct: 1148 ----RAEMTMCALLAKVQMKAKRTKEAVEVLKKALD-AISHSDKGPDATAISADCLYNLG 1202

Query: 282  LAHLAAEEYETA--LTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKK 339
            L ++     +    L + D    IS D +  ++         K+ + Q  +T+    L  
Sbjct: 1203 LCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLL- 1261

Query: 340  FVKIARNNFQSLDLVRASTML--GDIYNEKGYYNKASECFQQA 380
                      + + V+ +T L  G IY E G Y  A E F+QA
Sbjct: 1262 --------LDATETVKLNTFLNRGLIYVELGQYGFALEDFKQA 1296


>gi|187761311 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 61/252 (24%), Positives = 92/252 (36%), Gaps = 33/252 (13%)

Query: 174 KIDCGKKEAEAHMHMG----LLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLA 229
           K + G  E E  M M     LL E   +  + AE+ +      +G I K+     L  LA
Sbjct: 16  KKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKE-----LFKLA 70

Query: 230 CESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKME--------------AE 275
             +L  TY  L ++M  NK++     +        KE   K ME                
Sbjct: 71  TTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKA 130

Query: 276 ASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMT---- 331
           A  Y+   H   +  E  L V   Y +   DL     L +  +   K L S GE T    
Sbjct: 131 AQKYVERIHYIGQN-EPELLVAHAYTRYMGDLSGGQVLKKVAQRALK-LPSTGEGTQFYL 188

Query: 332 -EAIKYLKKFVKIARNNFQSLDL-VRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMS 389
            E +   ++F ++ R    +LDL ++    + +  N+   YN   + F +       L  
Sbjct: 189 FENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYN--MQIFNELDQAGSTLAR 246

Query: 390 MPLMDETKVHYG 401
             L D   VH G
Sbjct: 247 ETLEDGFPVHDG 258


>gi|187761309 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 61/252 (24%), Positives = 92/252 (36%), Gaps = 33/252 (13%)

Query: 174 KIDCGKKEAEAHMHMG----LLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLA 229
           K + G  E E  M M     LL E   +  + AE+ +      +G I K+     L  LA
Sbjct: 16  KKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKE-----LFKLA 70

Query: 230 CESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKME--------------AE 275
             +L  TY  L ++M  NK++     +        KE   K ME                
Sbjct: 71  TTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKA 130

Query: 276 ASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMT---- 331
           A  Y+   H   +  E  L V   Y +   DL     L +  +   K L S GE T    
Sbjct: 131 AQKYVERIHYIGQN-EPELLVAHAYTRYMGDLSGGQVLKKVAQRALK-LPSTGEGTQFYL 188

Query: 332 -EAIKYLKKFVKIARNNFQSLDL-VRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMS 389
            E +   ++F ++ R    +LDL ++    + +  N+   YN   + F +       L  
Sbjct: 189 FENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYN--MQIFNELDQAGSTLAR 246

Query: 390 MPLMDETKVHYG 401
             L D   VH G
Sbjct: 247 ETLEDGFPVHDG 258


>gi|187761307 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 61/252 (24%), Positives = 92/252 (36%), Gaps = 33/252 (13%)

Query: 174 KIDCGKKEAEAHMHMG----LLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLA 229
           K + G  E E  M M     LL E   +  + AE+ +      +G I K+     L  LA
Sbjct: 16  KKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKE-----LFKLA 70

Query: 230 CESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKME--------------AE 275
             +L  TY  L ++M  NK++     +        KE   K ME                
Sbjct: 71  TTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKA 130

Query: 276 ASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMT---- 331
           A  Y+   H   +  E  L V   Y +   DL     L +  +   K L S GE T    
Sbjct: 131 AQKYVERIHYIGQN-EPELLVAHAYTRYMGDLSGGQVLKKVAQRALK-LPSTGEGTQFYL 188

Query: 332 -EAIKYLKKFVKIARNNFQSLDL-VRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMS 389
            E +   ++F ++ R    +LDL ++    + +  N+   YN   + F +       L  
Sbjct: 189 FENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYN--MQIFNELDQAGSTLAR 246

Query: 390 MPLMDETKVHYG 401
             L D   VH G
Sbjct: 247 ETLEDGFPVHDG 258


>gi|8051608 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 61/252 (24%), Positives = 92/252 (36%), Gaps = 33/252 (13%)

Query: 174 KIDCGKKEAEAHMHMG----LLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLA 229
           K + G  E E  M M     LL E   +  + AE+ +      +G I K+     L  LA
Sbjct: 16  KKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKE-----LFKLA 70

Query: 230 CESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKME--------------AE 275
             +L  TY  L ++M  NK++     +        KE   K ME                
Sbjct: 71  TTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKA 130

Query: 276 ASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMT---- 331
           A  Y+   H   +  E  L V   Y +   DL     L +  +   K L S GE T    
Sbjct: 131 AQKYVERIHYIGQN-EPELLVAHAYTRYMGDLSGGQVLKKVAQRALK-LPSTGEGTQFYL 188

Query: 332 -EAIKYLKKFVKIARNNFQSLDL-VRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMS 389
            E +   ++F ++ R    +LDL ++    + +  N+   YN   + F +       L  
Sbjct: 189 FENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYN--MQIFNELDQAGSTLAR 246

Query: 390 MPLMDETKVHYG 401
             L D   VH G
Sbjct: 247 ETLEDGFPVHDG 258


>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
          Length = 1378

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 47/202 (23%), Positives = 78/202 (38%), Gaps = 46/202 (22%)

Query: 276 ASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIK 335
           A Y LG  H  A ++  A+  L+   + +  +            IA+VLQ  G+   A +
Sbjct: 204 ARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKRFMESECCVVIAQVLQDLGDFLAAKR 263

Query: 336 YLKKFVK-----------IARNNFQSLDLVRAS------------------TMLGDIYNE 366
            LKK  +           I +N    L +VR                      LGD++++
Sbjct: 264 ALKKAYRLGSQKPVQRAAICQNLQHVLAVVRLQQQLEEAEGRDPQGAMVICEQLGDLFSK 323

Query: 367 KGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIA------KAH---------QMMLT 411
            G + +A+E +Q+      EL+  P  +   +H  +A      K H         ++ L 
Sbjct: 324 AGDFPRAAEAYQKQL-RFAELLDRPGAERAIIHVSLATTLGDMKDHHGAVRHYEEELRLR 382

Query: 412 VNNYIESADLTSLNYLLSWKES 433
             N +E A  T LN  LS +E+
Sbjct: 383 SGNVLEEAK-TWLNIALSREEA 403


>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
           sapiens]
          Length = 860

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 12/94 (12%)

Query: 292 TALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQS-----QGEMTEAIKYLKKFVKIARN 346
           T   + + Y     D    L L +  + IA + +      +G + EAI+  K+ +K    
Sbjct: 257 TLYFISEDYATAHEDFQQSLELNKN-QPIAMLYKGLTFFHRGLLKEAIESFKEALK---- 311

Query: 347 NFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
             Q +D + A   LG  Y E G +  A+E FQ+A
Sbjct: 312 --QKVDFIDAYKSLGQAYRELGNFEAATESFQKA 343


>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
            sapiens]
          Length = 1614

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 52/223 (23%), Positives = 88/223 (39%), Gaps = 39/223 (17%)

Query: 167  FKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLN 226
            F I Q+ ++D G  E    M   L+Y          E+++   ++  G  W         
Sbjct: 1104 FTIYQIAEMDKGLSELSP-MQQALIYS-------FCENHDKAIEVLDGISWN-------- 1147

Query: 227  LLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDK-----KMEAEASYYLG 281
                 + +    LL+   ++ K  K+A+++L KA + A   SDK      + A+  Y LG
Sbjct: 1148 ----RAEMTMCALLAKVQMKAKRTKEAVEVLKKALD-AISHSDKGPDATAISADCLYNLG 1202

Query: 282  LAHLAAEEYETA--LTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKK 339
            L ++     +    L + D    IS D +   +         K+ + Q  +T+    L  
Sbjct: 1203 LCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLL- 1261

Query: 340  FVKIARNNFQSLDLVRASTML--GDIYNEKGYYNKASECFQQA 380
                      + + V+ +T L  G IY E G Y  A E F+QA
Sbjct: 1262 --------LDATETVKLNTFLNRGLIYVELGQYGFALEDFKQA 1296


>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
          Length = 1036

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 14/24 (58%), Positives = 19/24 (79%)

Query: 182 AEAHMHMGLLYEEDGQLLEAAEHY 205
           AEA+ ++G +Y+E GQL EA EHY
Sbjct: 79  AEAYSNLGNVYKERGQLQEAIEHY 102



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/235 (17%), Positives = 88/235 (37%), Gaps = 46/235 (19%)

Query: 168 KIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNL 227
           K   L  I+     A A  ++G ++   G++  A  H+E    L                
Sbjct: 167 KACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP-------------- 212

Query: 228 LACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYY-LGLAHLA 286
               + L  Y  L + + E + + +A+   ++A  ++   +         YY  GL  LA
Sbjct: 213 ----NFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLA 268

Query: 287 AEEYETALTVL----DTYCKISTDLDDDLSLGRGYEA-----------------IAKVLQ 325
            + Y  A+ +     D YC ++  L +  S+    +                  +A + +
Sbjct: 269 IDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKR 328

Query: 326 SQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
            QG + EA++  +K +++        +   A + L  +  ++G   +A   +++A
Sbjct: 329 EQGNIEEAVRLYRKALEVFP------EFAAAHSNLASVLQQQGKLQEALMHYKEA 377


>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
          Length = 1046

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 14/24 (58%), Positives = 19/24 (79%)

Query: 182 AEAHMHMGLLYEEDGQLLEAAEHY 205
           AEA+ ++G +Y+E GQL EA EHY
Sbjct: 89  AEAYSNLGNVYKERGQLQEAIEHY 112



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/235 (17%), Positives = 88/235 (37%), Gaps = 46/235 (19%)

Query: 168 KIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNL 227
           K   L  I+     A A  ++G ++   G++  A  H+E    L                
Sbjct: 177 KACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP-------------- 222

Query: 228 LACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYY-LGLAHLA 286
               + L  Y  L + + E + + +A+   ++A  ++   +         YY  GL  LA
Sbjct: 223 ----NFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLA 278

Query: 287 AEEYETALTVL----DTYCKISTDLDDDLSLGRGYEA-----------------IAKVLQ 325
            + Y  A+ +     D YC ++  L +  S+    +                  +A + +
Sbjct: 279 IDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKR 338

Query: 326 SQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
            QG + EA++  +K +++        +   A + L  +  ++G   +A   +++A
Sbjct: 339 EQGNIEEAVRLYRKALEVFP------EFAAAHSNLASVLQQQGKLQEALMHYKEA 387


>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
           sapiens]
          Length = 639

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 45/220 (20%), Positives = 83/220 (37%), Gaps = 17/220 (7%)

Query: 176 DCGKKEAEAHMHM-------------GLLYEEDGQLLEAAEHYE-AFHQLTQGRIWKDET 221
           +  K++AEAH  +             G  +EE+  L +  + +E    +L +G +     
Sbjct: 297 EMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVL 356

Query: 222 GRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYL- 280
                +      +  ++ L     EN++   AI  L +  E+  +     M    S+   
Sbjct: 357 LFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNE 416

Query: 281 GLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKF 340
            L   A E     L     Y  + T  ++    G G     ++L S    +  ++  + F
Sbjct: 417 SLQRQACETLRDWLRYTPAYAHLVTPAEEGAG-GAGLGPSKRILGSLLSDSLFLEVKELF 475

Query: 341 VKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
           +   R +  S+D       LG ++N  G Y+KA +CF  A
Sbjct: 476 LAAVRLDPTSID-PDVQCGLGVLFNLSGEYDKAVDCFTAA 514


>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
           sapiens]
          Length = 639

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 45/220 (20%), Positives = 83/220 (37%), Gaps = 17/220 (7%)

Query: 176 DCGKKEAEAHMHM-------------GLLYEEDGQLLEAAEHYE-AFHQLTQGRIWKDET 221
           +  K++AEAH  +             G  +EE+  L +  + +E    +L +G +     
Sbjct: 297 EMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVL 356

Query: 222 GRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYL- 280
                +      +  ++ L     EN++   AI  L +  E+  +     M    S+   
Sbjct: 357 LFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNE 416

Query: 281 GLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKF 340
            L   A E     L     Y  + T  ++    G G     ++L S    +  ++  + F
Sbjct: 417 SLQRQACETLRDWLRYTPAYAHLVTPAEEGAG-GAGLGPSKRILGSLLSDSLFLEVKELF 475

Query: 341 VKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
           +   R +  S+D       LG ++N  G Y+KA +CF  A
Sbjct: 476 LAAVRLDPTSID-PDVQCGLGVLFNLSGEYDKAVDCFTAA 514


>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo
           sapiens]
          Length = 602

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 45/220 (20%), Positives = 83/220 (37%), Gaps = 17/220 (7%)

Query: 176 DCGKKEAEAHMHM-------------GLLYEEDGQLLEAAEHYE-AFHQLTQGRIWKDET 221
           +  K++AEAH  +             G  +EE+  L +  + +E    +L +G +     
Sbjct: 260 EMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVL 319

Query: 222 GRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYL- 280
                +      +  ++ L     EN++   AI  L +  E+  +     M    S+   
Sbjct: 320 LFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNE 379

Query: 281 GLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKF 340
            L   A E     L     Y  + T  ++    G G     ++L S    +  ++  + F
Sbjct: 380 SLQRQACETLRDWLRYTPAYAHLVTPAEEGAG-GAGLGPSKRILGSLLSDSLFLEVKELF 438

Query: 341 VKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
           +   R +  S+D       LG ++N  G Y+KA +CF  A
Sbjct: 439 LAAVRLDPTSID-PDVQCGLGVLFNLSGEYDKAVDCFTAA 477


>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo
           sapiens]
          Length = 654

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 45/220 (20%), Positives = 83/220 (37%), Gaps = 17/220 (7%)

Query: 176 DCGKKEAEAHMHM-------------GLLYEEDGQLLEAAEHYE-AFHQLTQGRIWKDET 221
           +  K++AEAH  +             G  +EE+  L +  + +E    +L +G +     
Sbjct: 312 EMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVL 371

Query: 222 GRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYL- 280
                +      +  ++ L     EN++   AI  L +  E+  +     M    S+   
Sbjct: 372 LFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNE 431

Query: 281 GLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKF 340
            L   A E     L     Y  + T  ++    G G     ++L S    +  ++  + F
Sbjct: 432 SLQRQACETLRDWLRYTPAYAHLVTPAEEGAG-GAGLGPSKRILGSLLSDSLFLEVKELF 490

Query: 341 VKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQA 380
           +   R +  S+D       LG ++N  G Y+KA +CF  A
Sbjct: 491 LAAVRLDPTSID-PDVQCGLGVLFNLSGEYDKAVDCFTAA 529


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,731,296
Number of Sequences: 37866
Number of extensions: 689129
Number of successful extensions: 2118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 2040
Number of HSP's gapped (non-prelim): 122
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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