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Search of human proteins with 148596926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148596926 cyclin-dependent kinase 10 isoform a [Homo
sapiens]
(360 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 737 0.0
gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens] 593 e-170
gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens] 573 e-164
gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens] 523 e-148
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 362 e-100
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 362 e-100
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 362 e-100
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 362 e-100
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 362 e-100
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 362 e-100
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 361 e-100
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 361 e-100
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 259 3e-69
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 258 6e-69
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 250 1e-66
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 250 1e-66
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 249 4e-66
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 249 4e-66
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 240 2e-63
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 239 2e-63
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 239 4e-63
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 238 6e-63
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 236 2e-62
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 232 4e-61
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 229 2e-60
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 229 2e-60
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 229 2e-60
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 226 3e-59
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 226 3e-59
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 215 6e-56
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 737 bits (1902), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MAEPDLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQ 60
MAEPDLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQ
Sbjct: 1 MAEPDLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQ 60
Query: 61 TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYC 120
TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYC
Sbjct: 61 TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYC 120
Query: 121 EQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTA 180
EQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTA
Sbjct: 121 EQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTA 180
Query: 181 DFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLP 240
DFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLP
Sbjct: 181 DFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLP 240
Query: 241 GTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLL 300
GTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLL
Sbjct: 241 GTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLL 300
Query: 301 HFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP 360
HFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP
Sbjct: 301 HFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP 360
>gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens]
Length = 289
Score = 593 bits (1529), Expect = e-170
Identities = 289/289 (100%), Positives = 289/289 (100%)
Query: 72 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 131
MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 132 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 191
PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 192 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 251
VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 252 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR 311
VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR 240
Query: 312 ATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP 360
ATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP
Sbjct: 241 ATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP 289
>gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens]
Length = 283
Score = 573 bits (1477), Expect = e-164
Identities = 283/289 (97%), Positives = 283/289 (97%), Gaps = 6/289 (2%)
Query: 72 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 131
MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 132 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 191
PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 192 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 251
VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 252 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR 311
VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFM
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFM------ 234
Query: 312 ATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP 360
ATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP
Sbjct: 235 ATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP 283
>gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens]
Length = 272
Score = 523 bits (1346), Expect = e-148
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 72 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 131
MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 132 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 191
PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 192 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 251
VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 252 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR 311
VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKR 240
Query: 312 ATAGDCLESSYFKEKPL 328
ATAGDCLESSYFKEKPL
Sbjct: 241 ATAGDCLESSYFKEKPL 257
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 362 bits (928), Expect = e-100
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 408 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 467
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 468 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 527
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 528 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 587
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 588 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 647
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 648 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 707
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 708 PSMFPTWPAKSEQQRVKRGTSPRPPEG 734
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 362 bits (928), Expect = e-100
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 596
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 597 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 656
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 657 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 716
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 717 PSMFPTWPAKSEQQRVKRGTSPRPPEG 743
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 362 bits (928), Expect = e-100
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 385 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 444
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 445 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 504
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 505 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 564
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 565 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 624
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 625 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 684
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 685 PSMFPTWPAKSEQQRVKRGTSPRPPEG 711
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 362 bits (928), Expect = e-100
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 374 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 433
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 434 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 493
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 494 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 553
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 554 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 613
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 614 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 673
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 674 PSMFPTWPAKSEQQRVKRGTSPRPPEG 700
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 362 bits (928), Expect = e-100
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 163 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 222
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 223 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 282
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 283 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 342
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 343 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 402
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 403 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 462
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 463 PSMFPTWPAKSEQQRVKRGTSPRPPEG 489
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 362 bits (928), Expect = e-100
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 419 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 478
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 479 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 538
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 539 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 598
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 599 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 658
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 659 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 718
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 719 PSMFPTWPAKSEQQRVKRGTSPRPPEG 745
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 361 bits (926), Expect = e-100
Identities = 175/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 407 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 466
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 467 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 526
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVT WYRAPELLLG
Sbjct: 527 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 586
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP+V
Sbjct: 587 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVV 646
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 647 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 706
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 707 PSMFPTWPAKSEQQRVKRGTSPRPPEG 733
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 361 bits (926), Expect = e-100
Identities = 175/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
Query: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVT WYRAPELLLG
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 596
Query: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP+V
Sbjct: 597 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVV 656
Query: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 657 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 716
Query: 332 PELMPTFP----HHRNKR-AAPATSEG 353
P + PT+P R KR +P EG
Sbjct: 717 PSMFPTWPAKSEQQRVKRGTSPRPPEG 743
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 259 bits (662), Expect = 3e-69
Identities = 135/295 (45%), Positives = 198/295 (67%), Gaps = 9/295 (3%)
Query: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98
F+K+ +IGEGTYG+VY+A++ +T ++VALKK+R+D E +G+P +++REI+LL L+HPNI
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 99 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQ---VKCIVLQVLRGLQYLH 155
V L +VV ++ ++LV + QDL +++ TP SE +K + Q+L+G+ + H
Sbjct: 64 VRLLDVV--HNERKLYLVFEFLSQDLKKYMDS--TPGSELPLHLIKSYLFQLLQGVSFCH 119
Query: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
+ +IHRDLK NLL+ + G +K ADFGLARA+GVP++ T +VVTLWYRAPE+LLG+
Sbjct: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179
Query: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
TT++D+W++GCI AE++ + L PG SEI Q+ I ++LGTPSE+ WPG ++LP +
Sbjct: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY-KG 238
Query: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE-KPLP 329
S K L+ P L G LL L YDP +R TA L YF +P P
Sbjct: 239 SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSP 293
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 258 bits (659), Expect = 6e-69
Identities = 137/302 (45%), Positives = 198/302 (65%), Gaps = 16/302 (5%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++ F+K+ +IGEGTYG+VY+AR+ T E+VALKK+R+D E +G+P +++REI+LL L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 96 PNIVELKEVVVGNHLES-IFLVMGYCEQDL-----ASLLENMPTPFSEAQVKCIVLQVLR 149
PNIV+L +V+ H E+ ++LV + QDL AS L +P P +K + Q+L+
Sbjct: 61 PNIVKLLDVI---HTENKLYLVFEFLHQDLKKFMDASALTGIPLPL----IKSYLFQLLQ 113
Query: 150 GLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPEL 209
GL + H + ++HRDLK NLL+ +G +K ADFGLARA+GVPV+ T +VVTLWYRAPE+
Sbjct: 114 GLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEI 173
Query: 210 LLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKL 269
LLG +T++D+W++GCI AE++ R L PG SEI Q+ I + LGTP E +WPG + +
Sbjct: 174 LLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSM 233
Query: 270 PLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE--KP 327
P + S K + P L E G LL + YDP KR +A L +F++ KP
Sbjct: 234 PDY-KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 292
Query: 328 LP 329
+P
Sbjct: 293 VP 294
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 250 bits (639), Expect = 1e-66
Identities = 132/316 (41%), Positives = 187/316 (59%), Gaps = 11/316 (3%)
Query: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93
R V +F+ + IGEGTYG VY+A+D T E+VALKKVR+D EK+G PI+++REI +L +L
Sbjct: 722 RCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL 781
Query: 94 RHPNIVELKEVVVGNH--------LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVL 145
H ++V +KE+V + +LV Y + DL LLE+ FSE +K +
Sbjct: 782 IHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMK 841
Query: 146 QVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPV-KPMTPKVVTLWY 204
Q++ GL+Y H+ +HRD+K SN+L+ + G +K ADFGLAR Y +P T KV+TLWY
Sbjct: 842 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWY 901
Query: 205 RAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWP 264
R PELLLG T +ID+W+ GCIL EL +P+ E+ Q++LI +L G+P +WP
Sbjct: 902 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWP 961
Query: 265 GFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFK 324
KLP +KQ L+ +F ++ A L LL + DP KR TA L+S + K
Sbjct: 962 DVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLK 1021
Query: 325 EKPLPCEPELMPTFPH 340
+ L P PH
Sbjct: 1022 DVEL--SKMAPPDLPH 1035
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 250 bits (639), Expect = 1e-66
Identities = 132/316 (41%), Positives = 187/316 (59%), Gaps = 11/316 (3%)
Query: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93
R V +F+ + IGEGTYG VY+A+D T E+VALKKVR+D EK+G PI+++REI +L +L
Sbjct: 722 RCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL 781
Query: 94 RHPNIVELKEVVVGNH--------LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVL 145
H ++V +KE+V + +LV Y + DL LLE+ FSE +K +
Sbjct: 782 IHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMK 841
Query: 146 QVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPV-KPMTPKVVTLWY 204
Q++ GL+Y H+ +HRD+K SN+L+ + G +K ADFGLAR Y +P T KV+TLWY
Sbjct: 842 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWY 901
Query: 205 RAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWP 264
R PELLLG T +ID+W+ GCIL EL +P+ E+ Q++LI +L G+P +WP
Sbjct: 902 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWP 961
Query: 265 GFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFK 324
KLP +KQ L+ +F ++ A L LL + DP KR TA L+S + K
Sbjct: 962 DVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLK 1021
Query: 325 EKPLPCEPELMPTFPH 340
+ L P PH
Sbjct: 1022 DVEL--SKMAPPDLPH 1035
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 249 bits (635), Expect = 4e-66
Identities = 128/312 (41%), Positives = 186/312 (59%), Gaps = 13/312 (4%)
Query: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93
R V +F+ + IGEGTYG VY+ARD T E+VALKKVR+D EK+G PI+++REI +L +L
Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759
Query: 94 RHPNIVELKEVVVGNH--------LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVL 145
H +I+ +KE+V + +LV Y + DL LLE+ F+E +K +
Sbjct: 760 THQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 146 QVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPV-KPMTPKVVTLWY 204
Q++ GL Y H+ +HRD+K SN+L+ ++G +K ADFGLAR Y +P T KV+TLWY
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 879
Query: 205 RAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWP 264
R PELLLG T +ID+W+ GCIL EL +P+ E+ Q++LI ++ G+P +WP
Sbjct: 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWP 939
Query: 265 GFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFK 324
KLP +KQ L+ +F ++ A L L ++ DP KR TA L+ + +
Sbjct: 940 DVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999
Query: 325 EKPLPCEPELMP 336
+ EP MP
Sbjct: 1000 D----VEPSKMP 1007
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 249 bits (635), Expect = 4e-66
Identities = 128/312 (41%), Positives = 186/312 (59%), Gaps = 13/312 (4%)
Query: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93
R V +F+ + IGEGTYG VY+ARD T E+VALKKVR+D EK+G PI+++REI +L +L
Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759
Query: 94 RHPNIVELKEVVVGNH--------LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVL 145
H +I+ +KE+V + +LV Y + DL LLE+ F+E +K +
Sbjct: 760 THQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 146 QVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPV-KPMTPKVVTLWY 204
Q++ GL Y H+ +HRD+K SN+L+ ++G +K ADFGLAR Y +P T KV+TLWY
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 879
Query: 205 RAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWP 264
R PELLLG T +ID+W+ GCIL EL +P+ E+ Q++LI ++ G+P +WP
Sbjct: 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWP 939
Query: 265 GFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFK 324
KLP +KQ L+ +F ++ A L L ++ DP KR TA L+ + +
Sbjct: 940 DVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999
Query: 325 EKPLPCEPELMP 336
+ EP MP
Sbjct: 1000 D----VEPSKMP 1007
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 240 bits (612), Expect = 2e-63
Identities = 119/292 (40%), Positives = 187/292 (64%), Gaps = 5/292 (1%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++++ K+ +IGEGTYG+VY+ R T ++VA+KK+R++ E++G+P +++REI+LL LRH
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTP--FSEAQVKCIVLQVLRGLQY 153
PNIV L++V++ + ++L+ + DL L+++P + VK + Q+L+G+ +
Sbjct: 61 PNIVSLQDVLMQD--SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
Query: 154 LHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGT 213
H ++HRDLK NLL+ DKG +K ADFGLARA+G+P++ T +VVTLWYR+PE+LLG+
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGS 178
Query: 214 TTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVG 273
+T +D+W++G I AEL +PL G SEI Q+ I + LGTP+ +WP L
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
Query: 274 QYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 325
+ +P +L L E GL LL + +YDP KR + L YF +
Sbjct: 239 NTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 239 bits (611), Expect = 2e-63
Identities = 127/296 (42%), Positives = 183/296 (61%), Gaps = 7/296 (2%)
Query: 37 KEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRM---DKEKDGIPISSLREITLLLRL 93
K +EKL+ +GEG + VY+ARD T++IVA+KK+++ + KDGI ++LREI LL L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 94 RHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQY 153
HPNI+ L + H +I LV + E DL ++++ + + +K +L L+GL+Y
Sbjct: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
Query: 154 LHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGT 213
LH+++I+HRDLK +NLL+ + G +K ADFGLA+++G P + T +VVT WYRAPELL G
Sbjct: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
Query: 214 TTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVG 273
+DMWAVGCILAELL P LPG S++ Q+ I + LGTP+E WP LP
Sbjct: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
Query: 274 QYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLP 329
+ + P L H F + L L+ LF+++P R TA L+ YF +P P
Sbjct: 246 YVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGP 301
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 239 bits (609), Expect = 4e-63
Identities = 127/291 (43%), Positives = 184/291 (63%), Gaps = 4/291 (1%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++++EKL +IGEGTYG V++A++ +T EIVALK+VR+D + +G+P S+LREI LL L+H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 155
NIV L +V+ + + + LV +C+QDL ++ VK + Q+L+GL + H
Sbjct: 61 KNIVRLHDVLHSD--KKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
Query: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
++HRDLK NLL+ G +K ADFGLARA+G+PV+ + +VVTLWYR P++L G
Sbjct: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
Query: 216 QTTSIDMWAVGCILAELL-AHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQ 274
+TSIDMW+ GCI AEL A RPL PG Q+ I +LLGTP+E WP +KLP
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP 238
Query: 275 YSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 325
Y + +L + P L+ G LL L +P +R +A + L+ YF +
Sbjct: 239 YPMYPAT-TSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 238 bits (607), Expect = 6e-63
Identities = 117/292 (40%), Positives = 186/292 (63%), Gaps = 5/292 (1%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++++ K+ +IGEGTYG+VY+ R T ++VA+KK+R++ E++G+P +++REI+LL LRH
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTP--FSEAQVKCIVLQVLRGLQY 153
PNIV L++V++ + ++L+ + DL L+++P + VK + Q+L+G+ +
Sbjct: 61 PNIVSLQDVLMQD--SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
Query: 154 LHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGT 213
H ++HRDLK NLL+ DKG +K ADFGLARA+G+P++ T + +TLWYR+PE+LLG+
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGS 178
Query: 214 TTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVG 273
+T +D+W++G I AEL +PL G SEI Q+ I + LGTP+ +WP L
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
Query: 274 QYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 325
+ +P +L L E GL LL + +YDP KR + L YF +
Sbjct: 239 NTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 236 bits (603), Expect = 2e-62
Identities = 131/334 (39%), Positives = 198/334 (59%), Gaps = 16/334 (4%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++ + KL ++GEGTY VY+ R T+ +VALK++R++ E +G P +++RE++LL L+H
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 247
Query: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 155
NIV L ++V + +S+ LV Y ++DL +++ S VK + Q+LRGL Y H
Sbjct: 248 ANIVTLHDIVHTD--KSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCH 305
Query: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
R ++HRDLK NLL+ +KG +K ADFGLARA VP K + +VVTLWYR P++LLG++
Sbjct: 306 RRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSE 365
Query: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
+T IDMW VGCI E+ + RPL PG++ ++ LI +LLGTPS+ WPG S Y
Sbjct: 366 YSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNY 425
Query: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE--KPLPCEPE 333
+ K L + P L G+ L+ Y+ KKR +A + ++ YF+ + PE
Sbjct: 426 NFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPE 485
Query: 334 LMPTF----------PHHRNKRAAPATSEGQSKR 357
+ F P RN + P T G+++R
Sbjct: 486 SVSIFSLKEIQLQKDPGFRNS-SYPETGHGKNRR 518
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 232 bits (591), Expect = 4e-61
Identities = 125/311 (40%), Positives = 182/311 (58%), Gaps = 12/311 (3%)
Query: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
C V ++EKL +IG+GT+G V++AR +T + VALKKV M+ EK+G PI++LREI +L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 93 LRHPNIVELKEVV------VGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQ 146
L+H N+V L E+ SI+LV +CE DLA LL N+ F+ +++K ++
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 147 VLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM----TPKVVTL 202
+L GL Y+HRN I+HRD+K +N+L+T G +K ADFGLARA+ + T +VVTL
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTL 192
Query: 203 WYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENI 262
WYR PELLLG ID+W GCI+AE+ P++ G +E HQ+ LI QL G+ + +
Sbjct: 193 WYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEV 252
Query: 263 WPGFSKLPLVGQYSLRKQPYNNLKHKFPWL--SEAGLRLLHFLFMYDPKKRATAGDCLES 320
WP L + L K +K + L L+ L + DP +R + D L
Sbjct: 253 WPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNH 312
Query: 321 SYFKEKPLPCE 331
+F P+P +
Sbjct: 313 DFFWSDPMPSD 323
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 229 bits (585), Expect = 2e-60
Identities = 130/328 (39%), Positives = 191/328 (58%), Gaps = 11/328 (3%)
Query: 5 DLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKE--------FEKLNRIGEGTYGIVYRA 56
D+ Q L+ ++ E P R+ R S+ + + KL+++GEGTY V++
Sbjct: 132 DIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKG 191
Query: 57 RDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLV 116
R T+ +VALK++R++ E +G P +++RE++LL L+H NIV L +++ + S+ LV
Sbjct: 192 RSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDR--SLTLV 248
Query: 117 MGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGC 176
Y + DL L++ S VK + Q+LRGL Y H I+HRDLK NLL+ ++G
Sbjct: 249 FEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGE 308
Query: 177 VKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHR 236
+K ADFGLARA VP K + +VVTLWYR P++LLG+T +T IDMW VGCI E+ R
Sbjct: 309 LKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGR 368
Query: 237 PLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAG 296
PL PG++ ++ LI +LLGTP+E WPG + YS L + P L G
Sbjct: 369 PLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDG 428
Query: 297 LRLLHFLFMYDPKKRATAGDCLESSYFK 324
+ LL L +Y+ K R +A L SYF+
Sbjct: 429 IHLLSSLLLYESKSRMSAEAALSHSYFR 456
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 229 bits (585), Expect = 2e-60
Identities = 130/328 (39%), Positives = 191/328 (58%), Gaps = 11/328 (3%)
Query: 5 DLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKE--------FEKLNRIGEGTYGIVYRA 56
D+ Q L+ ++ E P R+ R S+ + + KL+++GEGTY V++
Sbjct: 102 DIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKG 161
Query: 57 RDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLV 116
R T+ +VALK++R++ E +G P +++RE++LL L+H NIV L +++ + S+ LV
Sbjct: 162 RSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDR--SLTLV 218
Query: 117 MGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGC 176
Y + DL L++ S VK + Q+LRGL Y H I+HRDLK NLL+ ++G
Sbjct: 219 FEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGE 278
Query: 177 VKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHR 236
+K ADFGLARA VP K + +VVTLWYR P++LLG+T +T IDMW VGCI E+ R
Sbjct: 279 LKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGR 338
Query: 237 PLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAG 296
PL PG++ ++ LI +LLGTP+E WPG + YS L + P L G
Sbjct: 339 PLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDG 398
Query: 297 LRLLHFLFMYDPKKRATAGDCLESSYFK 324
+ LL L +Y+ K R +A L SYF+
Sbjct: 399 IHLLSSLLLYESKSRMSAEAALSHSYFR 426
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 229 bits (585), Expect = 2e-60
Identities = 130/328 (39%), Positives = 191/328 (58%), Gaps = 11/328 (3%)
Query: 5 DLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKE--------FEKLNRIGEGTYGIVYRA 56
D+ Q L+ ++ E P R+ R S+ + + KL+++GEGTY V++
Sbjct: 102 DIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKG 161
Query: 57 RDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLV 116
R T+ +VALK++R++ E +G P +++RE++LL L+H NIV L +++ + S+ LV
Sbjct: 162 RSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDR--SLTLV 218
Query: 117 MGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGC 176
Y + DL L++ S VK + Q+LRGL Y H I+HRDLK NLL+ ++G
Sbjct: 219 FEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGE 278
Query: 177 VKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHR 236
+K ADFGLARA VP K + +VVTLWYR P++LLG+T +T IDMW VGCI E+ R
Sbjct: 279 LKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGR 338
Query: 237 PLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAG 296
PL PG++ ++ LI +LLGTP+E WPG + YS L + P L G
Sbjct: 339 PLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDG 398
Query: 297 LRLLHFLFMYDPKKRATAGDCLESSYFK 324
+ LL L +Y+ K R +A L SYF+
Sbjct: 399 IHLLSSLLLYESKSRMSAEAALSHSYFR 426
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 226 bits (575), Expect = 3e-59
Identities = 118/289 (40%), Positives = 177/289 (61%), Gaps = 5/289 (1%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++ + KL+++GEGTY VY+ + TD +VALK++R++ E +G P +++RE++LL L+H
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 226
Query: 96 PNIVELKEVVVGNHLE-SIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 154
NIV L +++ H E S+ LV Y ++DL L++ + VK + Q+LRGL Y
Sbjct: 227 ANIVTLHDII---HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYC 283
Query: 155 HRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTT 214
HR ++HRDLK NLL+ ++G +K ADFGLARA +P K + +VVTLWYR P++LLG+T
Sbjct: 284 HRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGST 343
Query: 215 TQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQ 274
+T IDMW VGCI E+ RPL PG++ Q+ I ++LGTP+E WPG
Sbjct: 344 DYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKT 403
Query: 275 YSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYF 323
Y+ K L P L G LL L ++ + R +A D ++ +F
Sbjct: 404 YNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 452
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 226 bits (575), Expect = 3e-59
Identities = 118/289 (40%), Positives = 177/289 (61%), Gaps = 5/289 (1%)
Query: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
++ + KL+++GEGTY VY+ + TD +VALK++R++ E +G P +++RE++LL L+H
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 220
Query: 96 PNIVELKEVVVGNHLE-SIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 154
NIV L +++ H E S+ LV Y ++DL L++ + VK + Q+LRGL Y
Sbjct: 221 ANIVTLHDII---HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYC 277
Query: 155 HRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTT 214
HR ++HRDLK NLL+ ++G +K ADFGLARA +P K + +VVTLWYR P++LLG+T
Sbjct: 278 HRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGST 337
Query: 215 TQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQ 274
+T IDMW VGCI E+ RPL PG++ Q+ I ++LGTP+E WPG
Sbjct: 338 DYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKT 397
Query: 275 YSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYF 323
Y+ K L P L G LL L ++ + R +A D ++ +F
Sbjct: 398 YNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 215 bits (547), Expect = 6e-56
Identities = 118/297 (39%), Positives = 173/297 (58%), Gaps = 4/297 (1%)
Query: 42 LNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLR-HPNIVE 100
L RIGEG +GIV++A+ +T EIVALKKV + + +DG P +LREI L + + +V+
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 101 LKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFII 160
LK V H L + DLA ++ + P ++AQVK + +L+G+ + H N I+
Sbjct: 67 LKAVFP--HGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIV 124
Query: 161 HRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM-TPKVVTLWYRAPELLLGTTTQTTS 219
HRDLK +NLL++ G +K ADFGLAR + + T +V T WYRAPELL G
Sbjct: 125 HRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQG 184
Query: 220 IDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRK 279
+D+W+VGCI+ ELL PL PG ++I Q+ ++++LGTP+ +WP ++LP + S ++
Sbjct: 185 VDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKE 244
Query: 280 QPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMP 336
Q L+ P +S L LL +Y P +R A L YF PLP P +P
Sbjct: 245 QVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELP 301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,480,261
Number of Sequences: 37866
Number of extensions: 651044
Number of successful extensions: 3226
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 736
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 1280
Number of HSP's gapped (non-prelim): 920
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.