Guide to the Human Genome
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Search of human proteins with 148491057

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148491057 crystallin, gamma A [Homo sapiens]
         (174 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148491057 crystallin, gamma A [Homo sapiens]                       385   e-107
gi|148491074 crystallin, gamma B [Homo sapiens]                       291   2e-79
gi|10518338 crystallin, gamma C [Homo sapiens]                        290   3e-79
gi|13377002 crystallin, gamma D [Homo sapiens]                        278   2e-75
gi|8922120 crystallin, gamma S [Homo sapiens]                         203   7e-53
gi|4758074 crystallin, beta B3 [Homo sapiens]                         112   2e-25
gi|4503063 crystallin, beta B2 [Homo sapiens]                         110   6e-25
gi|89886227 absent in melanoma 1-like [Homo sapiens]                  110   8e-25
gi|4503061 crystallin, beta B1 [Homo sapiens]                         108   2e-24
gi|12056461 crystallin, beta A3 [Homo sapiens]                        105   2e-23
gi|16936542 crystallin, beta A2 [Homo sapiens]                        103   8e-23
gi|16936540 crystallin, beta A2 [Homo sapiens]                        103   8e-23
gi|7019357 crystallin, beta A2 [Homo sapiens]                         103   8e-23
gi|4503059 crystallin, beta A4 [Homo sapiens]                         102   2e-22
gi|62988361 absent in melanoma 1 [Homo sapiens]                        97   5e-21
gi|21389517 gammaN-crystallin [Homo sapiens]                           83   1e-16
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi...    82   2e-16
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform...    29   2.3  
gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]          27   6.8  
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]           27   6.8  
gi|7706113 protocadherin 12 precursor [Homo sapiens]                   27   6.8  
gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]       27   8.9  

>gi|148491057 crystallin, gamma A [Homo sapiens]
          Length = 174

 Score =  385 bits (989), Expect = e-107
 Identities = 174/174 (100%), Positives = 174/174 (100%)

Query: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60
           MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR
Sbjct: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60

Query: 61  GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120
           GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE
Sbjct: 61  GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120

Query: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY 174
           IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY
Sbjct: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY 174


>gi|148491074 crystallin, gamma B [Homo sapiens]
          Length = 175

 Score =  291 bits (745), Expect = 2e-79
 Identities = 129/175 (73%), Positives = 153/175 (87%), Gaps = 1/175 (0%)

Query: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60
           MGKITFYEDR FQGR Y C +DCPNL+ YFSRCNSIRV+SGCWM+YERPNYQGHQYFLRR
Sbjct: 1   MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR 60

Query: 61  GKYPDYQHWMGLSDSVQSCRII-PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLP 119
           G+YPDYQ WMGLSDS++SC +I PH+ ++++++Y+RD+ RG MSELTDDC  V + F L 
Sbjct: 61  GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT 120

Query: 120 EIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY 174
           EI+SL+VLEG W+LYEMPNYRGRQYLLRPG+YRR+ DWG  +AKVGSLRRV DLY
Sbjct: 121 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY 175


>gi|10518338 crystallin, gamma C [Homo sapiens]
          Length = 174

 Score =  290 bits (743), Expect = 3e-79
 Identities = 130/174 (74%), Positives = 147/174 (84%)

Query: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60
           MGKITFYEDR FQGR Y   +DCPNL+ YFSRCNSIRV+SGCWMLYERPNYQG QY LRR
Sbjct: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60

Query: 61  GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120
           G+YPDYQ WMGLSDS++SC +IP T SH+LRLYER+D++GLM EL++DC  + + F L E
Sbjct: 61  GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120

Query: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY 174
           I SLHVLEGCWVLYE+PNYRGRQYLLRP +YRR  DWG  DAK GSLRRV DLY
Sbjct: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY 174


>gi|13377002 crystallin, gamma D [Homo sapiens]
          Length = 174

 Score =  278 bits (711), Expect = 2e-75
 Identities = 125/172 (72%), Positives = 143/172 (83%)

Query: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60
           MGKIT YEDR FQGR Y C SD PNL+ Y SRCNS RVDSGCWMLYE+PNY G QYFLRR
Sbjct: 1   MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60

Query: 61  GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120
           G Y D+Q WMGLSDSV+SCR+IPH+ SH++RLYER+DYRG M E T+DC+C+ + FR  E
Sbjct: 61  GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120

Query: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172
           I+SL+VLEG WVLYE+ NYRGRQYLL PGDYRRY DWG  +A+VGSLRRV D
Sbjct: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172


>gi|8922120 crystallin, gamma S [Homo sapiens]
          Length = 178

 Score =  203 bits (516), Expect = 7e-53
 Identities = 88/172 (51%), Positives = 120/172 (69%), Gaps = 2/172 (1%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGK 62
           KITFYED++FQGR Y+C  DC +   Y SRCNSI+V+ G W +YERPN+ G+ Y L +G+
Sbjct: 7   KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66

Query: 63  YPDYQHWMGLSDSVQSCRII--PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120
           YP+YQ WMGL+D + SCR +  P    +K++++E+ D+ G M E T+DC  + E F + E
Sbjct: 67  YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126

Query: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172
           I+S  VLEG W+ YE+PNYRGRQYLL   +YR+  DWG A   V S RR+ +
Sbjct: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178


>gi|4758074 crystallin, beta B3 [Homo sapiens]
          Length = 211

 Score =  112 bits (280), Expect = 2e-25
 Identities = 63/180 (35%), Positives = 98/180 (54%), Gaps = 15/180 (8%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLR-VYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           K+  YE  +FQG+     ++CP+L      +  SI+V+SG W+ +E   ++G Q+ L +G
Sbjct: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84

Query: 62  KYPDYQHWMGL--SDSVQSCRII----PHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115
            YP +  W     SDS+ S R +    PH   HKL L+E   + G   E+ DD   VP L
Sbjct: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPH---HKLHLFENPAFSGRKMEIVDDD--VPSL 139

Query: 116 FR---LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172
           +       + S+  + G WV YE P YRGRQY+   G+YR +++W  +  ++ S+RR+ D
Sbjct: 140 WAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 1/74 (1%)

Query: 87  SHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL 146
           S+K+ LYE ++++G   EL+ +C  + +   L ++ S+ V  G W+ +E   +RG Q++L
Sbjct: 23  SYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFVL 81

Query: 147 RPGDYRRYHDWGGA 160
             GDY R+  W  +
Sbjct: 82  EKGDYPRWDAWSNS 95



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 3   KITFYEDRDFQGRCYNCISD-CPNLRV--YFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           K+  +E+  F GR    + D  P+L    +  R  S+R  +G W+ YE P Y+G QY   
Sbjct: 115 KLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174

Query: 60  RGKYPDYQHWMGLSDSVQSCRIIPHTSSHK 89
           RG+Y  +  W      +QS R I     HK
Sbjct: 175 RGEYRHWNEWDASQPQLQSVRRIRDQKWHK 204


>gi|4503063 crystallin, beta B2 [Homo sapiens]
          Length = 205

 Score =  110 bits (275), Expect = 6e-25
 Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLR-VYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           KI  +E  +FQG  +     CPNL+     +  S+ V +G W+ YE+ N +G Q+   +G
Sbjct: 18  KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77

Query: 62  KYPDYQHWMGL--SDSVQSCRIIPHTSS-HKLRLYERDDYRGLMSELTDDCACVPELFR- 117
           +YP +  W     +DS+ S R I   S  HK+ LYE  ++ G   E+ DD   VP     
Sbjct: 78  EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDD--VPSFHAH 135

Query: 118 --LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDL 173
               ++ S+ V  G WV Y+ P YRG QYLL  GDY+   D+G    +V S+RR+ D+
Sbjct: 136 GYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDM 193



 Score = 54.3 bits (129), Expect = 5e-08
 Identities = 32/90 (35%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 3   KITFYEDRDFQGRCYNCISD-CPNLRV--YFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           KI  YE+ +F G+    I D  P+     Y  + +S+RV SG W+ Y+ P Y+G QY L 
Sbjct: 108 KIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLE 167

Query: 60  RGKYPDYQHWMGLSDSVQSCRIIPHTSSHK 89
           +G Y D   +      VQS R I     H+
Sbjct: 168 KGDYKDSSDFGAPHPQVQSVRRIRDMQWHQ 197


>gi|89886227 absent in melanoma 1-like [Homo sapiens]
          Length = 616

 Score =  110 bits (274), Expect = 8e-25
 Identities = 59/172 (34%), Positives = 88/172 (51%), Gaps = 8/172 (4%)

Query: 7   YEDRDFQGRCYNCISDCPNLRV-------YFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           YE   FQGR +    D  NL+        + +   S+RV  GCW+ YE+  ++GHQY L 
Sbjct: 128 YEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLE 187

Query: 60  RGKYPDYQHWMGLSDSVQSCRII-PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRL 118
            G+YPD+ HW G  + + S R+I        + L+E  D+ G   E++     V  +   
Sbjct: 188 EGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEVSKALPDVELVQHG 247

Query: 119 PEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRV 170
           P   ++HVL G WV Y+   + G QY+L  G YR   DWG  ++ + SL+ V
Sbjct: 248 PSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPV 299



 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 50/146 (34%), Positives = 71/146 (48%), Gaps = 12/146 (8%)

Query: 35  SIRVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMGLSDSVQS-------CRIIPHTSS 87
           S  V +G W+LY +P ++   Y L  G+YP  + W     SV S       C  +     
Sbjct: 63  SATVSAGLWLLYPKPLFEDTPYILEPGEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGE 122

Query: 88  HKLRLYERDDYRGLMSELTDDCACV--PELFRLP---EIYSLHVLEGCWVLYEMPNYRGR 142
            +  +YE   ++G   E++ D   +  PE  + P    + SL VL GCWV YE   +RG 
Sbjct: 123 PRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGH 182

Query: 143 QYLLRPGDYRRYHDWGGADAKVGSLR 168
           QYLL  G+Y  +  WGG D  + SLR
Sbjct: 183 QYLLEEGEYPDWSHWGGYDELLTSLR 208



 Score = 74.3 bits (181), Expect = 5e-14
 Identities = 48/177 (27%), Positives = 85/177 (48%), Gaps = 12/177 (6%)

Query: 4   ITFYEDRDFQGRCYNCISDCPNLRV--YFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           +  +E  DF+G         P++ +  +     +I V SG W+ Y+   + G QY L +G
Sbjct: 219 VVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKG 278

Query: 62  KYPDYQHWMGLSDSVQSCRIIPHTSSH------KLRLYERDDYRGLMSELTDDCACVPEL 115
            Y + + W   + ++ S + +     H      K++L+ R D+ G      DD A +P  
Sbjct: 279 VYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPAS 338

Query: 116 FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGG-ADAKVGSLRRVT 171
           FR P+  S  V  G W+L++  N+ G Q++L  G++      G  A   +GSL++V+
Sbjct: 339 FR-PQ--SCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKVS 392



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 4/169 (2%)

Query: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60
           + KI  +   DF G  ++   D   L   F R  S RV  G W+L++  N++G Q+ L  
Sbjct: 310 VSKIQLFSRPDFLGDHFSFEDDQAALPASF-RPQSCRVHGGSWILFDETNFEGDQHILSE 368

Query: 61  GKYPDYQHWMGLSDSVQSC--RIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRL 118
           G++P       L+ +V     ++  H S   + LY  + + G   EL+ +   +      
Sbjct: 369 GEFPTLTAMGCLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGFN 428

Query: 119 PEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSL 167
             + S+ +  G WVL E  ++RGRQ+L+   +   +  + G   +VGSL
Sbjct: 429 NHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTYSGTQ-RVGSL 476



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 26/89 (29%), Positives = 45/89 (50%)

Query: 80  RIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNY 139
           R++   S+ ++ L+  +  +G   +LT+       L +  ++ S  V  G W+LY  P +
Sbjct: 20  RVVWDYSTPEISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLF 79

Query: 140 RGRQYLLRPGDYRRYHDWGGADAKVGSLR 168
               Y+L PG+Y     WG +D  VGSL+
Sbjct: 80  EDTPYILEPGEYPTSEAWGTSDPSVGSLK 108


>gi|4503061 crystallin, beta B1 [Homo sapiens]
          Length = 252

 Score =  108 bits (271), Expect = 2e-24
 Identities = 61/175 (34%), Positives = 96/175 (54%), Gaps = 5/175 (2%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLRVY-FSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           ++  +E  +FQGR      +C NL    F R  SI V +G W+ +E+ N++G  + L +G
Sbjct: 60  RLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKG 119

Query: 62  KYPDYQHWMGL--SDSVQSCRIIP-HTSSHKLRLYERDDYRGLMSELTDDCACVPELFRL 118
           +YP +  W     SD + S R I      HK+ L+E  +++G   E+  D A    ++  
Sbjct: 120 EYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGF 179

Query: 119 PE-IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172
            + + S+ V  G WV Y+ P YRG QYLL PGD+R +++WG    ++ SLRR+ D
Sbjct: 180 SDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRD 234


>gi|12056461 crystallin, beta A3 [Homo sapiens]
          Length = 215

 Score =  105 bits (263), Expect = 2e-23
 Identities = 58/182 (31%), Positives = 100/182 (54%), Gaps = 14/182 (7%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLRVY-FSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           KIT Y+  +FQG+     S CPN+    F    S++V+SG W+ YE  ++ G Q+ L RG
Sbjct: 32  KITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERG 91

Query: 62  KYPDYQHWMGLS----DSVQSCRII--PHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115
           +YP +  W G +    + + S R I   +    K+ ++E++++ G   E++DD   +  +
Sbjct: 92  EYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQAM 151

Query: 116 -FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWG--GADAKVGSLR 168
            +   E+ S+ +  G WV Y+ P YRG QY+L      GDY+ + +WG     +++ S+R
Sbjct: 152 GWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIR 211

Query: 169 RV 170
           R+
Sbjct: 212 RI 213


>gi|16936542 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  103 bits (257), Expect = 8e-23
 Identities = 58/180 (32%), Positives = 99/180 (55%), Gaps = 14/180 (7%)

Query: 4   ITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           +T +++ DFQGR    +SDC N+  R    R  S++V++G W+ +E P++QG Q+ L +G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 62  KYPDYQHWMGL----SDSVQSCR--IIPHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115
            YP +  W G     S+ + S R  +  + +  ++ L+E D+++G   +L DD   +P +
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133

Query: 116 -FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWGGADAKVGSLRRV 170
            +   ++ SL V  G WV Y+ P YRG QY+L      G++  Y +  G  A  G L+ +
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL-GTQAHTGQLQSI 192



 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 29/80 (36%), Positives = 47/80 (58%)

Query: 83  PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGR 142
           P  +   L L++ +D++G    L  DCA V E   LP + S+ V  G WV +E P+++G+
Sbjct: 7   PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66

Query: 143 QYLLRPGDYRRYHDWGGADA 162
           Q++L  GDY R+  W G+ +
Sbjct: 67  QFILEKGDYPRWSAWSGSSS 86



 Score = 47.4 bits (111), Expect = 6e-06
 Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLRVY---FSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           ++T +E  +FQG  ++ + D P+L           S++V SG W+ Y+ P Y+G+QY L 
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 60  RGKY 63
           R ++
Sbjct: 167 RDRH 170


>gi|16936540 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  103 bits (257), Expect = 8e-23
 Identities = 58/180 (32%), Positives = 99/180 (55%), Gaps = 14/180 (7%)

Query: 4   ITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           +T +++ DFQGR    +SDC N+  R    R  S++V++G W+ +E P++QG Q+ L +G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 62  KYPDYQHWMGL----SDSVQSCR--IIPHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115
            YP +  W G     S+ + S R  +  + +  ++ L+E D+++G   +L DD   +P +
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133

Query: 116 -FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWGGADAKVGSLRRV 170
            +   ++ SL V  G WV Y+ P YRG QY+L      G++  Y +  G  A  G L+ +
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL-GTQAHTGQLQSI 192



 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 29/80 (36%), Positives = 47/80 (58%)

Query: 83  PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGR 142
           P  +   L L++ +D++G    L  DCA V E   LP + S+ V  G WV +E P+++G+
Sbjct: 7   PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66

Query: 143 QYLLRPGDYRRYHDWGGADA 162
           Q++L  GDY R+  W G+ +
Sbjct: 67  QFILEKGDYPRWSAWSGSSS 86



 Score = 47.4 bits (111), Expect = 6e-06
 Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLRVY---FSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           ++T +E  +FQG  ++ + D P+L           S++V SG W+ Y+ P Y+G+QY L 
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 60  RGKY 63
           R ++
Sbjct: 167 RDRH 170


>gi|7019357 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  103 bits (257), Expect = 8e-23
 Identities = 58/180 (32%), Positives = 99/180 (55%), Gaps = 14/180 (7%)

Query: 4   ITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           +T +++ DFQGR    +SDC N+  R    R  S++V++G W+ +E P++QG Q+ L +G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 62  KYPDYQHWMGL----SDSVQSCR--IIPHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115
            YP +  W G     S+ + S R  +  + +  ++ L+E D+++G   +L DD   +P +
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133

Query: 116 -FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWGGADAKVGSLRRV 170
            +   ++ SL V  G WV Y+ P YRG QY+L      G++  Y +  G  A  G L+ +
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL-GTQAHTGQLQSI 192



 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 29/80 (36%), Positives = 47/80 (58%)

Query: 83  PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGR 142
           P  +   L L++ +D++G    L  DCA V E   LP + S+ V  G WV +E P+++G+
Sbjct: 7   PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66

Query: 143 QYLLRPGDYRRYHDWGGADA 162
           Q++L  GDY R+  W G+ +
Sbjct: 67  QFILEKGDYPRWSAWSGSSS 86



 Score = 47.4 bits (111), Expect = 6e-06
 Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 3   KITFYEDRDFQGRCYNCISDCPNLRVY---FSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           ++T +E  +FQG  ++ + D P+L           S++V SG W+ Y+ P Y+G+QY L 
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 60  RGKY 63
           R ++
Sbjct: 167 RDRH 170


>gi|4503059 crystallin, beta A4 [Homo sapiens]
          Length = 196

 Score =  102 bits (253), Expect = 2e-22
 Identities = 59/183 (32%), Positives = 97/183 (53%), Gaps = 16/183 (8%)

Query: 3   KITFYEDRDFQGRCYNCISDCPN-LRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
           K+  +++  FQGR +   ++CP+ L + F    S++V SG W+ +E   +QG QY L RG
Sbjct: 13  KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72

Query: 62  KYPDYQHWMGLS-------DSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPE 114
           +YP +  W G +        S +      H  S +L ++E++++ G   EL+DD   +  
Sbjct: 73  EYPSWDAWGGNTAYPAERLTSFRPAACANHRDS-RLTIFEQENFLGKKGELSDDYPSLQA 131

Query: 115 L-FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWG--GADAKVGSL 167
           + +   E+ S HV  G WV  + P YRG QY+L      GDY+ + +WG      +V S+
Sbjct: 132 MGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSI 191

Query: 168 RRV 170
           RR+
Sbjct: 192 RRI 194


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 97.4 bits (241), Expect = 5e-21
 Identities = 54/185 (29%), Positives = 93/185 (50%), Gaps = 17/185 (9%)

Query: 3    KITFYEDRDFQGRCYNCISDCPNL--------------RVYFSRCNSIRVDSGCWMLYER 48
            K+  YE   F+G+C    +   +                + F+   S++V  G W+ YE+
Sbjct: 1219 KVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEK 1278

Query: 49   PNYQGHQYFLRRGKYPDYQHWMGLSDSVQSCR-IIPHTSSHKLRLYERDDY--RGLMSEL 105
            P + GHQY L  G+Y D++ W G +  +QS R I+   S+  + +Y   ++  +G   ++
Sbjct: 1279 PGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPILGDFSNAHMIMYSEKNFGSKGSSIDV 1338

Query: 106  TDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVG 165
                A + E     +  S++VL G WV YE P++ G QY+L  G Y  + DWGG + K+ 
Sbjct: 1339 LGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNCKIS 1398

Query: 166  SLRRV 170
            S++ +
Sbjct: 1399 SVQPI 1403



 Score = 84.7 bits (208), Expect = 4e-17
 Identities = 51/155 (32%), Positives = 76/155 (49%), Gaps = 19/155 (12%)

Query: 35   SIRVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMGLSDSVQSCRI-------IPHTSS 87
            S++V  G W++YE P +QG  + L  G+YPD   W   +  + S R        +   + 
Sbjct: 1158 SMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIGSMRPLKMGGRKVEFPTD 1217

Query: 88   HKLRLYERDDYRGLMSEL-TDDCACVPELFRLPE-----------IYSLHVLEGCWVLYE 135
             K+ +YE+  + G   EL T  C+ V E     E           + S+ VL G WV YE
Sbjct: 1218 PKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYE 1277

Query: 136  MPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRV 170
             P + G QYLL  G+YR +  WGG + ++ SLR +
Sbjct: 1278 KPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPI 1312



 Score = 83.2 bits (204), Expect = 1e-16
 Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 6/169 (3%)

Query: 3    KITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGK 62
            +I  + +  FQG   +       +   FS   S RV  G W++Y+  N+ G+QY L  G 
Sbjct: 1416 QIHLFSEPQFQGHSQSFEETTSQIDDSFST-KSCRVSGGSWVVYDGENFTGNQYVLEEGH 1474

Query: 63   YPDYQHWMGLSDSV--QSCRIIP-HTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLP 119
            YP     MG       +S R I    S   + L+ER+D++G   EL  +   +  L    
Sbjct: 1475 YPCLSA-MGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETVNLRSLGFNT 1533

Query: 120  EIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLR 168
            +I S+ V+ G WV YE  +YRGRQ+LL P +   ++++ G   ++GSLR
Sbjct: 1534 QIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGC-RQIGSLR 1581



 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 17/183 (9%)

Query: 2    GKITFYEDRDFQGRCYNCISDCPNLRVY-FSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60
            GK+  Y + D   +C    SD  +   +  S    I+V  GCW+LYE+PN++GH   L  
Sbjct: 1022 GKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLEE 1081

Query: 61   GKYPDYQHWMGLSDSVQ--------------SCR-IIPHTSSHKLRLYERDDYRGLMSEL 105
            G+      W G+ D ++              S R ++       + L+   +  G++S  
Sbjct: 1082 GELELSGLW-GIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGILSSY 1140

Query: 106  TDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVG 165
             DD   +     + +  S+ V  G W++YE P ++G  ++L PG+Y     W    A +G
Sbjct: 1141 FDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIG 1200

Query: 166  SLR 168
            S+R
Sbjct: 1201 SMR 1203



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 13/70 (18%)

Query: 118  LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGAD-------------AKV 164
            L  +  + V+ GCW+LYE PN+ G    L  G+      WG  D               +
Sbjct: 1051 LSPVILIKVVRGCWILYEQPNFEGHSIPLEEGELELSGLWGIEDILERHEEAESDKPVVI 1110

Query: 165  GSLRRVTDLY 174
            GS+R V   Y
Sbjct: 1111 GSIRHVVQDY 1120


>gi|21389517 gammaN-crystallin [Homo sapiens]
          Length = 182

 Score = 83.2 bits (204), Expect = 1e-16
 Identities = 40/110 (36%), Positives = 60/110 (54%), Gaps = 3/110 (2%)

Query: 2   GKITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
           GKIT YE + F G+      DC N   R + +R NSI V+SG W+ +  P+++G Q+ L 
Sbjct: 6   GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65

Query: 60  RGKYPDYQHWMGLSDSVQSCRII-PHTSSHKLRLYERDDYRGLMSELTDD 108
            G YPD+  W   SD + SCR +  H    +L ++E  ++ G   E  +D
Sbjct: 66  HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLED 115



 Score = 57.8 bits (138), Expect = 5e-09
 Identities = 28/84 (33%), Positives = 43/84 (51%)

Query: 87  SHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL 146
           S K+ LYE   + G   E+  DC    +   +  + S+HV  G WV +  P++RG+Q++L
Sbjct: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64

Query: 147 RPGDYRRYHDWGGADAKVGSLRRV 170
             GDY  +  W      +GS R V
Sbjct: 65  EHGDYPDFFRWNSHSDHMGSCRPV 88


>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
           sapiens]
          Length = 1022

 Score = 82.0 bits (201), Expect = 2e-16
 Identities = 52/176 (29%), Positives = 85/176 (48%), Gaps = 8/176 (4%)

Query: 3   KITFYEDRDFQGRCYNC---ISDCPNLRVY---FSRCNSIRVDSGCWMLYERPNYQGHQY 56
           K+  YE   F G+       I   PN       F R  SIRV  G W+ YE+ +++G Q+
Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591

Query: 57  FLRRGKYPDYQHWMGLSDSVQSCRIIP-HTSSHKLRLYERDDYRGLMSELTD-DCACVPE 114
            L  G + D      LS  + S R +  +     + L+E D   G   ++T+ + + + E
Sbjct: 592 LLEEGDFEDSNACGALSSPILSFRYLQANFIESSVTLFESDLESGKFIDITNQEISDLEE 651

Query: 115 LFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRV 170
           +    +  S+HV  G WV Y+   + G QY+L  G Y+ + DWGG++  + S+R +
Sbjct: 652 IGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPI 707



 Score = 65.1 bits (157), Expect = 3e-11
 Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 10/146 (6%)

Query: 31  SRCNSIRVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMGLSDSVQSCRIIP------H 84
           S+  SI V SG W+ Y++  + G QY L +GKY  +  W G ++ + S R I       +
Sbjct: 656 SKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPIQLEPLGIN 715

Query: 85  TSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQY 144
              H L+ + +  ++G   + T++ + +  L       S  VL GCW+LY   +      
Sbjct: 716 EPPHLLKAFSKPGFQGECIDFTEETSDLTSLMPC----SFKVLRGCWLLYYQEDMFVNHC 771

Query: 145 LLRPGDYRRYHDWGGADAKVGSLRRV 170
           +L  G Y      G   +KV SL+ +
Sbjct: 772 VLEEGLYADLTSCGCPASKVKSLKPI 797



 Score = 47.0 bits (110), Expect = 8e-06
 Identities = 43/161 (26%), Positives = 66/161 (40%), Gaps = 10/161 (6%)

Query: 12  FQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMG 71
           FQG C +   +  +L      C S +V  GCW+LY + +   +   L  G Y D      
Sbjct: 729 FQGECIDFTEETSDLTSLMP-C-SFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGC 786

Query: 72  LSDSVQSCRIIPHTSSH-KLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGC 130
            +  V+S + I +      + L+  +   G    L +    V          S+ V  G 
Sbjct: 787 PASKVKSLKPIDYVFEEPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGL 846

Query: 131 WVLYEMPNYRGRQYLLRPGD---YRRYHDWGGADAKVGSLR 168
           W+ YE  N+ GRQ LLRP +   +  +  W      +GSLR
Sbjct: 847 WIAYEGSNFLGRQILLRPNEIPNWTAFSRW----KTIGSLR 883



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 7/54 (12%)

Query: 124 LHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAK-------VGSLRRV 170
           + V+ GCW+LYE P++RG++ +L  G+     DW   + +       +GSL+RV
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRV 434



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 30/131 (22%), Positives = 56/131 (42%), Gaps = 33/131 (25%)

Query: 36  IRVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWM----------GLSDSVQSCRIIPHT 85
           I+V  GCW+LYE+P+++G +  L  G+    + W+           +  S++  R++   
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLK--RVLKDC 438

Query: 86  SSHKLRLYERDDYRGLMSELTDDCACVP----------ELFRLPEIYSLHVLEGCWVLYE 135
           S  ++ L+ +            D AC P          E   + +  S  V  G W+ Y 
Sbjct: 439 SIPEIELFPQ-----------SDPACCPVYIQRAVPNLEELNISKSVSFTVKSGVWLAYP 487

Query: 136 MPNYRGRQYLL 146
             N++G+  +L
Sbjct: 488 DINFKGQATVL 498


>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
            [Homo sapiens]
          Length = 1045

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 12/40 (30%), Positives = 19/40 (47%)

Query: 50   NYQGHQYFLRRGKYPDYQHWMGLSDSVQSCRIIPHTSSHK 89
            +++ H Y+ R      ++ WM +  S  S    PH  SHK
Sbjct: 1001 HFKSHVYYFRAESEYTFERWMEVIRSATSSASRPHVLSHK 1040


>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 16/63 (25%), Positives = 28/63 (44%), Gaps = 12/63 (19%)

Query: 20  ISDCPNLRVYFSRCN----SIRVDSGC------WMLYERPNYQGHQYFLRRGKY--PDYQ 67
           + + P LR +F  C      + +  GC      W+++ RP    H Y +RR  +   D+ 
Sbjct: 394 MGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHP 453

Query: 68  HWM 70
            W+
Sbjct: 454 RWI 456


>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 16/63 (25%), Positives = 28/63 (44%), Gaps = 12/63 (19%)

Query: 20  ISDCPNLRVYFSRCN----SIRVDSGC------WMLYERPNYQGHQYFLRRGKY--PDYQ 67
           + + P LR +F  C      + +  GC      W+++ RP    H Y +RR  +   D+ 
Sbjct: 394 MGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHP 453

Query: 68  HWM 70
            W+
Sbjct: 454 RWI 456


>gi|7706113 protocadherin 12 precursor [Homo sapiens]
          Length = 1184

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 7/68 (10%)

Query: 99   RGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYR-RYHDW 157
            R  + ELT D   V ++ +L  +  LH  +        PN+RG +YL +PG  R    D 
Sbjct: 946  RNPVEELTVDSPPVQQISQLLSL--LHQGQ----FQPKPNHRGNKYLAKPGGSRSAIPDT 999

Query: 158  GGADAKVG 165
             G  A+ G
Sbjct: 1000 DGPSARAG 1007


>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 1064

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 14/33 (42%), Positives = 15/33 (45%), Gaps = 2/33 (6%)

Query: 5   TFYEDRDFQGRCYN--CISDCPNLRVYFSRCNS 35
           T Y  RD  G CY   C  DC  +R   S C S
Sbjct: 270 TIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPS 302


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.144    0.493 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,323,182
Number of Sequences: 37866
Number of extensions: 322940
Number of successful extensions: 755
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 638
Number of HSP's gapped (non-prelim): 45
length of query: 174
length of database: 18,247,518
effective HSP length: 95
effective length of query: 79
effective length of database: 14,650,248
effective search space: 1157369592
effective search space used: 1157369592
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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