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Search of human proteins with 14717407
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14717407 TATA box-binding protein-associated factor 2F [Homo
sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14717407 TATA box-binding protein-associated factor 2F [Homo ... 690 0.0
gi|51477718 TATA box binding protein-associated factor, RNA poly... 394 e-110
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 52 6e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 52 1e-06
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 51 1e-06
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 51 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 51 2e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 49 5e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 49 5e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 49 5e-06
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 49 9e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 9e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 1e-05
gi|38044112 restin isoform b [Homo sapiens] 47 3e-05
gi|4506751 restin isoform a [Homo sapiens] 47 3e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 47 3e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 46 6e-05
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 46 6e-05
gi|38569484 kinesin family member 21A [Homo sapiens] 46 6e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 7e-05
gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens] 45 7e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 45 1e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 45 1e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 1e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 1e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 1e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 1e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 1e-04
gi|56550043 sarcolemma associated protein [Homo sapiens] 45 1e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 45 1e-04
>gi|14717407 TATA box-binding protein-associated factor 2F [Homo
sapiens]
Length = 349
Score = 690 bits (1780), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MSKSKDDAPHELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDR 60
MSKSKDDAPHELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDR
Sbjct: 1 MSKSKDDAPHELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDR 60
Query: 61 VPLASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASK 120
VPLASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASK
Sbjct: 61 VPLASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASK 120
Query: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTR 180
KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTR
Sbjct: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTR 180
Query: 181 WEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQD 240
WEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQD
Sbjct: 181 WEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQD 240
Query: 241 EEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAK 300
EEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAK
Sbjct: 241 EEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAK 300
Query: 301 RQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
RQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK
Sbjct: 301 RQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
>gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
Length = 462
Score = 394 bits (1011), Expect = e-110
Identities = 212/377 (56%), Positives = 276/377 (73%), Gaps = 29/377 (7%)
Query: 1 MSKSKDDAPHELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDR 60
MS+S+D+ P E+E+QFILRLP E+A TVR +S V +KD+L I+L PDGRH +V V+
Sbjct: 87 MSESQDEVPDEVENQFILRLPLEHACTVRNLARSQSVKMKDKLKIDLLPDGRHAVVEVED 146
Query: 61 VPLASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASK 120
VPLA+KLVDLPCV+ESL+T+DKKTFYKTADI QMLV T DGD++ EEP ASTDP +
Sbjct: 147 VPLAAKLVDLPCVIESLRTLDKKTFYKTADISQMLVCTADGDIHLSPEEPAASTDPNIVR 206
Query: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKK-------------KYIESPDVEKEVK 167
KK++ +E+K +W HGIT PLKNVRK+RFRKT KK +YIESPDVE EVK
Sbjct: 207 KKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK 266
Query: 168 RLLSTDAEAVSTRWEIIAEDETKEAENQGL---DISSPGMSGHRQGHDSLEHDELREIFN 224
RLL +DAEAVSTRWE+IAED TKE E+QG + S GMS H+QGH S E+D LRE+F+
Sbjct: 267 RLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFS 326
Query: 225 DLSSSS------------EDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENE 272
D S++ EDEDE + +D+E+ +EE LERQLQ + ES Q++ NE
Sbjct: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESG-QYRANE 385
Query: 273 GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDRE 332
GT+ +VM IQKQI+ + KL + Q++A+RQ+DLIMKVENL LKN FQ+VL++L+ +E ++
Sbjct: 386 GTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQK 445
Query: 333 KEQLSSLQEELESLLEK 349
E+L SLQE+L+ L+K
Sbjct: 446 NEKLISLQEQLQRFLKK 462
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 52.4 bits (124), Expect = 6e-07
Identities = 52/216 (24%), Positives = 106/216 (49%), Gaps = 31/216 (14%)
Query: 164 KEVKRLLSTDAEAVSTRWE--IIAEDETKEAEN---QGLDISSPGMSGHRQGHDSLEH-- 216
+E K+ L DAEA+S R E +A D+ ++ +N Q LD + + RQ +LE
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450
Query: 217 ---DELREIFNDLSSS-SEDED----ETQHQDEEDINI-------IDTEEDLERQ----- 256
D+L +S+ +E+ D E + ++ + +++ ++ +E+ ERQ
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510
Query: 257 --LQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQED--LIMKVENL 312
++D ++ D+ + + +++Q++ M+ +L+E +D + ED L ++V
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 313 ALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLE 348
A+K +F+ L ++ + +K L ELE+ LE
Sbjct: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELE 1606
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 10/140 (7%)
Query: 215 EHDELREIFNDLSSSSEDEDETQHQDEE-DINIIDTEEDLERQLQD---KLNESDEQHQ- 269
+H +L E N L+ + E E + EE + +++LE L D ++ E +E++Q
Sbjct: 881 KHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQI 940
Query: 270 ---ENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVEN--LALKNRFQAVLDE 324
E + + +++Q+D +G Q+ Q E I K+E L L+++ + E
Sbjct: 941 LQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE 1000
Query: 325 LKQKEDREKEQLSSLQEELE 344
K EDR E S L EE E
Sbjct: 1001 KKLMEDRIAECSSQLAEEEE 1020
Score = 40.0 bits (92), Expect = 0.003
Identities = 49/213 (23%), Positives = 89/213 (41%), Gaps = 41/213 (19%)
Query: 150 KTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDIS------SPG 203
K +K + D ++E++ EA ++R EI A+ + E + + L+
Sbjct: 1645 KQLRKLQAQMKDYQRELE-------EARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 1697
Query: 204 MSGHRQGHDSLEHDELR-EIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLN 262
S + H E DEL EI N S S ++D + LE ++
Sbjct: 1698 SSERARRHAEQERDELADEITNSASGKSA--------------LLDEKRRLEARIAQLEE 1743
Query: 263 ESDEQHQENEGTNQLVMGIQKQIDNMKGKLQ------ETQDRAKRQ-----EDLIMKVEN 311
E +E+ E N Q+D + +L + D A++Q ++L K++
Sbjct: 1744 ELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQE 1803
Query: 312 L--ALKNRFQAVLDELKQKEDREKEQLSSLQEE 342
L A+K++F+A + L+ K + +EQL +E
Sbjct: 1804 LEGAVKSKFKATISALEAKIGQLEEQLEQEAKE 1836
Score = 38.5 bits (88), Expect = 0.009
Identities = 70/351 (19%), Positives = 146/351 (41%), Gaps = 60/351 (17%)
Query: 47 LHPDGRHGIVRVDRVPLASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPP 106
LH + +VR L +++ +L ES K K + D+ + L + +L
Sbjct: 1104 LHKNNALKVVR----ELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL-EALKTELEDT 1158
Query: 107 VEEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEV 166
++ A + + ++++ + KK + + R+ TA ++ E + K
Sbjct: 1159 LDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 167 KRLLSTDAEAVSTRWEIIA-------------EDETKEAENQGLDISSPGMSGHRQGHDS 213
K L + + + T + +A E + K+ + Q ++ + G R +
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVEL 1278
Query: 214 LEH-DELREIFNDLSSSSEDEDETQHQDEEDI-----NIIDTEEDLERQLQDKLNES--- 264
E +L+ +++S+ E+ ++ + +D + DT+E L+ + + KLN S
Sbjct: 1279 AEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI 1338
Query: 265 -----------DEQHQENEGTNQL---VMGIQKQIDNMKGKLQ------ETQDRAKRQ-- 302
++Q +E E L V+ +Q Q+ + K K+ E+ + AK++
Sbjct: 1339 RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398
Query: 303 ---EDLIMKVENLAL--------KNRFQAVLDELKQKEDREKEQLSSLQEE 342
E L ++E AL KNR Q LD+L D +++ S+L+++
Sbjct: 1399 KDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK 1449
Score = 34.7 bits (78), Expect = 0.13
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 16/127 (12%)
Query: 230 SEDEDETQHQDEEDINIIDTE-------EDLERQLQDKLNESDEQHQENEGTNQLVMGIQ 282
+ E+E Q +DEE + + + + E++ER+ Q L E + ++ + +L +
Sbjct: 848 TRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAE 907
Query: 283 KQIDNMKGKLQETQD-------RAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQ 335
+ + K QE ++ R + +E+ ++N K + QA + +L+++ D E+
Sbjct: 908 EMRARLAAKKQELEEILHDLESRVEEEEERNQILQN--EKKKMQAHIQDLEEQLDEEEGA 965
Query: 336 LSSLQEE 342
LQ E
Sbjct: 966 RQKLQLE 972
Score = 30.8 bits (68), Expect = 1.9
Identities = 58/284 (20%), Positives = 124/284 (43%), Gaps = 46/284 (16%)
Query: 78 KTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASKKKDKDKEKKFIWNH--- 134
+T+ K K Q ++ + D E AS + +K+D +E + +
Sbjct: 1102 ETLHKNNALKVVRELQAQIAELQEDF----ESEKASRNKAEKQKRDLSEELEALKTELED 1157
Query: 135 --GITLPLKNVRKRRFRKTAKKKYI---ESPDVEKEVKRLLSTDAEAVSTRWEIIAEDET 189
T + +R +R ++ A+ K E+ + E +++ + A A+ E + + +
Sbjct: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
Query: 190 KEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDT 249
+A + ++QG LE D +E+ ++ + + E++H+ ++ +D
Sbjct: 1218 FKAN----------LEKNKQG---LETDN-KELACEVKVLQQVKAESEHKRKK----LDA 1259
Query: 250 EEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKV 309
+ ++L K++E D E + +Q ++DN+ L+E + + +
Sbjct: 1260 QV---QELHAKVSEGDRLRVE---LAEKASKLQNELDNVSTLLEEAEKKGIK-----FAK 1308
Query: 310 ENLALKNRFQAVLDELKQKEDREKEQLSS----LQEELESLLEK 349
+ +L+++ Q EL Q+E R+K LSS L+EE SL E+
Sbjct: 1309 DAASLESQLQDT-QELLQEETRQKLNLSSRIRQLEEEKNSLQEQ 1351
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 51.6 bits (122), Expect = 1e-06
Identities = 58/230 (25%), Positives = 112/230 (48%), Gaps = 34/230 (14%)
Query: 153 KKKYIESP---DVEKEVKRLLSTDAEAVSTRWE--IIAEDE---TKEAENQGLDISSPGM 204
KKK +S + +EVKR L D E +S R E + A D+ TK Q LD +
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Query: 205 SGHRQGHDSLEH-----DELREIFNDLSSS-SEDED----ETQHQDEEDINI-------I 247
RQ +LE D+L +S+ +E+ D E + ++ + +++ +
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 248 DTEEDLER-------QLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAK 300
+ + +LER +++D ++ D+ + + +++Q++ MK +L+E +D +
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 301 RQEDLIMKVE-NL-ALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLE 348
ED +++E NL A+K +F+ L ++ + +K+QL E+E+ LE
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/142 (24%), Positives = 70/142 (49%), Gaps = 13/142 (9%)
Query: 218 ELREIFNDLSSSSEDEDET-QHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQ 276
EL EI +DL + E+E+E QH E + ++LE QL+++ + + E T
Sbjct: 912 ELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIM-----------KVENLA-LKNRFQAVLDE 324
+ ++++ ++ + + K ED I K ++LA LKN+ +A++ +
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD 1031
Query: 325 LKQKEDREKEQLSSLQEELESL 346
L+++ RE++Q L++ L
Sbjct: 1032 LEERLRREEKQRQELEKTRRKL 1053
Score = 38.5 bits (88), Expect = 0.009
Identities = 52/233 (22%), Positives = 102/233 (43%), Gaps = 16/233 (6%)
Query: 119 SKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVS 178
S K++D+ K + + +K+ + A ++ I + E E K+L S +AE +
Sbjct: 1628 SANKNRDEAIKQL--RKLQAQMKDCMRELDDTRASREEILAQAKENE-KKLKSMEAEMIQ 1684
Query: 179 TRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQH 238
+ E+ A + K Q D + ++ + G +L +E R + ++ E+ +E Q
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIA-NSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
Query: 239 QDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDR 298
E + + Q+ LN Q+NE Q +++Q +K KLQE +
Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQ---QLERQNKELKVKLQEMEGT 1800
Query: 299 AKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKE----QLSSLQEELESLL 347
K + K AL+ + A L+E E +E++ Q+ +++L+ +L
Sbjct: 1801 VKSK----YKASITALEAKI-AQLEEQLDNETKERQAACKQVRRTEKKLKDVL 1848
Score = 37.7 bits (86), Expect = 0.015
Identities = 55/248 (22%), Positives = 111/248 (44%), Gaps = 32/248 (12%)
Query: 102 DLYPPVEEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPD 161
+L +E AS + +K+D +E + LK + TA ++ + S
Sbjct: 1115 ELQEDLESERASRNKAEKQKRDLGEELE---------ALKTELEDTLDSTAAQQELRSKR 1165
Query: 162 VEKEVKRLLSTDAEAVSTRWEIIAEDETKEAEN-----QGLDISSPGMSGHRQGHDSLEH 216
E+EV L T E T I E K ++ + L+ + + + +LE+
Sbjct: 1166 -EQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 217 DELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQ 276
E E+ N++ + + +++H+ ++ E L+ +LQ K NE + E
Sbjct: 1225 -ERGELANEVKVLLQGKGDSEHKRKK------VEAQLQ-ELQVKFNEGERVRTE---LAD 1273
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQL 336
V +Q ++DN+ G L ++ ++ + + + AL+++ Q EL Q+E+R+K L
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSK-----LTKDFSALESQLQDT-QELLQEENRQKLSL 1327
Query: 337 SSLQEELE 344
S+ +++E
Sbjct: 1328 STKLKQVE 1335
Score = 31.6 bits (70), Expect = 1.1
Identities = 59/327 (18%), Positives = 134/327 (40%), Gaps = 51/327 (15%)
Query: 63 LASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASKKK 122
L S++ +L +ES + K + D+ + L + +L ++ A + ++ +++
Sbjct: 1109 LESQISELQEDLESERASRNKAEKQKRDLGEEL-EALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 123 DKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWE 182
+ + KK + T + R+ A ++ E + K VK L + +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL----- 1222
Query: 183 IIAEDETKEAENQ-GLDISSPGMSGHRQGHDSLEHDELREIFND---LSSSSEDEDETQH 238
E+E E N+ + + G S H++ + EL+ FN+ + + D+
Sbjct: 1223 ---ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
Query: 239 QDEEDINIIDTEED------------LERQLQDKLNESDEQHQENEGTNQLVMGIQKQID 286
+ +++ + ++ D LE QLQD E++++ + + ++ + +
Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 287 NMKGKLQETQ------------------DRAKRQEDLIMKVENL-ALKNRFQAVLDELKQ 327
+ + +L+E + D K+ ED + +E +K + Q L+ L Q
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 328 KE-------DREKEQLSSLQEELESLL 347
+ D+ ++ + LQ+EL+ LL
Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Score = 31.2 bits (69), Expect = 1.4
Identities = 19/90 (21%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 254 ERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLA 313
E++L+D L + D++ + E ++ +K +L+E ++ A+R A
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRAN---------A 1891
Query: 314 LKNRFQAVLDELKQKEDREKEQLSSLQEEL 343
+ + Q L++ + D ++SSL+ +L
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 30.0 bits (66), Expect = 3.2
Identities = 27/132 (20%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 226 LSSSSEDEDETQHQDEEDINI---IDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQ 282
L+ + E+E + + + E I + + E +RQ Q + +E ++ + G L + +
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
Query: 283 KQIDNMKGKLQETQDRAKRQEDLI---MKVENLALK--NRFQAVLDELKQKEDREKEQLS 337
++++ +L+E + + +LI +K NL + N + QK + ++QL
Sbjct: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLE 1784
Query: 338 SLQEELESLLEK 349
+EL+ L++
Sbjct: 1785 RQNKELKVKLQE 1796
Score = 28.5 bits (62), Expect = 9.4
Identities = 19/96 (19%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 253 LERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENL 312
LE QL ++ E ++ T + + + Q+D+ + ++ +D+A + + +++
Sbjct: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKR- 1877
Query: 313 ALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLE 348
L+E +++ R LQ ELE E
Sbjct: 1878 --------QLEEAEEEAQRANASRRKLQRELEDATE 1905
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 51.2 bits (121), Expect = 1e-06
Identities = 60/250 (24%), Positives = 111/250 (44%), Gaps = 35/250 (14%)
Query: 105 PPVEEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEK 164
PPV +P AS+D + S D+ W G KN +K + RK KK
Sbjct: 84 PPVSQPAASSDSETSDSDDE-------WTFGSN---KNKKKGKARKIEKK---------G 124
Query: 165 EVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIF- 223
+K+ + A + S+ + AE E E + D S S S E +E + +
Sbjct: 125 TMKKQANKTASSGSSDKDSSAESSAPE-EGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYG 183
Query: 224 NDLSSSSED----EDETQHQDEEDI-NIIDTEEDLER--QLQDKLNESDEQHQENEGTNQ 276
DL ED E T+ + E+++ N I+ E L+R +++ KL + ++ ++ + Q
Sbjct: 184 EDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQ 243
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQL 336
++Q ++QE+Q + +E + E L K++ ++ELK + ++ K +
Sbjct: 244 ----EEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQ---AMEELKAEREKRKNRT 296
Query: 337 SSLQEELESL 346
+ L + + L
Sbjct: 297 AELLAKKQPL 306
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/242 (19%), Positives = 118/242 (48%), Gaps = 22/242 (9%)
Query: 120 KKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST-DAEAVS 178
+KK +D K+ N L K R + + K E+ + +E+ +L ++ +
Sbjct: 333 EKKLRDANKELEKNTNKIKQLSQ-EKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIK 391
Query: 179 TRW---EIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDE 235
+W ++ AE ++ + L ++ ++ ++ E D++R+ D+ + ++ +E
Sbjct: 392 VKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKE-----EADQIRKNCQDMIKTYQESEE 446
Query: 236 TQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQID---NMKGKL 292
+ +E D + T+ +LE+Q+Q+K ++ + H + + L ++ +D ++ K+
Sbjct: 447 IK-SNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 293 QETQDRAKRQEDLIMKVENLALKNRFQ--------AVLDELKQKEDREKEQLSSLQEELE 344
+ +D R ED + K + + + + + D+L+++ R K+++ +L+EE+E
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE 565
Query: 345 SL 346
SL
Sbjct: 566 SL 567
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/131 (24%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 217 DELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQ 276
DE ++LS E + + + + ++ + T + L+ QLQ E + +E E N
Sbjct: 510 DERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNS 569
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKN-RFQAVLDELKQKEDREKEQ 335
L+ +QK I+ + KR+ +L++ E L KN + Q+ + L+ + D+
Sbjct: 570 LINDLQKDIEGSR----------KRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCS 619
Query: 336 LSSLQEELESL 346
S LQ + E +
Sbjct: 620 ESQLQSQCEQM 630
Score = 30.4 bits (67), Expect = 2.5
Identities = 30/143 (20%), Positives = 67/143 (46%), Gaps = 9/143 (6%)
Query: 213 SLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESD----EQH 268
S D L EI ++L S+ E + + + + E+ +QDK + + +
Sbjct: 157 SASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVL---FEKCVQDKYLQQEHIIKKLI 213
Query: 269 QENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENL--ALKNRFQAVLDELK 326
+EN+ +L + I + DN++ +L++ + K+ + I ++E+ L +A D+L
Sbjct: 214 KENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLI 273
Query: 327 QKEDREKEQLSSLQEELESLLEK 349
++ K + L +E+ +E+
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQ 296
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 50.8 bits (120), Expect = 2e-06
Identities = 47/244 (19%), Positives = 115/244 (47%), Gaps = 15/244 (6%)
Query: 108 EEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVK 167
EE + D + +K+++ +E+K +W + +R+ + + +KK + + +E +
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQE-----EKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 168 RLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLS 227
R+ + + + E++ E E K E + + Q E +E +
Sbjct: 561 RMREREKK-MREEEEMMREQEEKMQEQEE-KMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
Query: 228 SSSEDEDETQHQDE---EDINIIDTEEDLERQLQDKLNESDEQHQENE----GTNQLVMG 280
E+ED+ Q Q+E E + +E+ + ++K+ E +E+ +E E G + +
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678
Query: 281 IQKQIDNMKGKLQETQDRAKRQEDLIM-KVENLALKNRFQAVLDELKQKEDREKEQLSSL 339
++++ + K++E +++ + QE+ + + E + + +E+++KE+R ++Q +
Sbjct: 679 QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738
Query: 340 QEEL 343
QE L
Sbjct: 739 QERL 742
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/237 (18%), Positives = 105/237 (44%), Gaps = 18/237 (7%)
Query: 120 KKKDKDKEKKFIWNHG----ITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL---LST 172
KKK+ + ++K I L +K ++++ R +++ +++E+ R L
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
+ + + E + E + E +G ++ + ELRE +L +
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
++ + E++ + + EE + Q ++K+ +E+ E E KQ+ + K+
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQ-EEKMWRQEERLWEQE----------KQMREQEQKM 354
Query: 293 QETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
++ ++R Q++ + + E + +E Q+E+R +E+ ++EE E++ E+
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Score = 37.4 bits (85), Expect = 0.020
Identities = 34/242 (14%), Positives = 110/242 (45%), Gaps = 28/242 (11%)
Query: 108 EEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVK 167
+E + + K ++++K ++++ +W K R+ + R+ + + + + + +
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQ----EKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 168 RLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLS 227
++ + WE ++ +E E + + + + ++ ++ ++
Sbjct: 501 KMWDQEERM----WE--QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
Query: 228 SSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDN 287
E+E + + + + EE++ R+ ++K+ E +E+ +E E +++
Sbjct: 555 KMREEERMREREKK-----MREEEEMMREQEEKMQEQEEKMREQE----------EKMWE 599
Query: 288 MKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLL 347
+ K+QE +++ QE+ + + E +++ Q + + ++E++ +EQ + E+ E +
Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEE---EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 348 EK 349
E+
Sbjct: 657 EQ 658
Score = 37.0 bits (84), Expect = 0.026
Identities = 54/267 (20%), Positives = 116/267 (43%), Gaps = 26/267 (9%)
Query: 108 EEPVASTDPKASKKKDK--DKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKE 165
EE + + K K+++K +E++ G + + + RR K +++ E + EKE
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEG-KMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 166 VK--RLLSTDAEAVSTRWEIIAEDETKEAEN-------------QGLDISSPGMSGHRQG 210
++ + L E + + E + E E K E Q + Q
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 211 HDSLEHDE-LREIFNDLSSSSED-EDETQHQDEEDINIIDT----EEDLERQLQDKLNES 264
E DE LRE + + E E + Q+EE I + EE+ R+ ++K+ +
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 265 DEQHQENEGTNQLVMGIQKQIDNM--KGKLQETQDRAKRQEDLIMKVENLALKNRFQAVL 322
+E E E + +Q + + + K+QE +++ QE+ I E + + +
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Query: 323 DELKQKEDREKEQLSSLQEELESLLEK 349
++++++ED+ EQ ++++ + + ++
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQ 505
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/254 (21%), Positives = 115/254 (45%), Gaps = 25/254 (9%)
Query: 108 EEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVK 167
EE + + K ++++K E++ L ++ ++ +R+ K E E+E K
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQE--------LKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 168 RLLSTDAEAVSTRWEIIAEDETK------EAENQGLDISSPGMSGHRQGHDSLEHDELRE 221
+ E + + E I E E K + Q I RQ E +E R+
Sbjct: 348 --MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 222 --IFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQD---KLNESDEQHQENEGTNQ 276
++ E +++ + Q+EE + +LE +QD KL E +E+ QE E +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE---E 462
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENL-ALKNRFQAVLDELKQKEDREKEQ 335
+ +++I + K+QE +++ RQE L+ + E + + + +++ ++E++ +EQ
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 336 LSSLQEELESLLEK 349
+Q + E + E+
Sbjct: 523 EEKMQRQEEKMREQ 536
Score = 31.2 bits (69), Expect = 1.4
Identities = 53/254 (20%), Positives = 105/254 (41%), Gaps = 38/254 (14%)
Query: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAV--- 177
KK+ D+ K + KN R+ R KK ++ +V + + S E +
Sbjct: 125 KKNSDEVKSSFKKRQEKMNEKNYTFRK-RVVIKKPWLRLGEVTAQKRPENSLLEETLHFD 183
Query: 178 -STRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDET 236
+ R E TKE + L++ +++ +EL+E +L +
Sbjct: 184 HAVRMGTYIEKLTKERDAPSLELY----------RNTITDEELKEKNAELQEKLRLVES- 232
Query: 237 QHQDEEDINIIDTEEDLER--------QLQ---DKLNES--------DEQHQENEGTNQL 277
+ E +N+ D + LER QLQ D+L + Q +ENE N L
Sbjct: 233 -EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLL 291
Query: 278 VMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALK--NRFQAVLDELKQKEDREKEQ 335
++++ + K+QE +++ QE I + E + + ++++++ED+ Q
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 336 LSSLQEELESLLEK 349
++E+ E + E+
Sbjct: 352 EEKIREQEEKIREQ 365
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/254 (21%), Positives = 115/254 (45%), Gaps = 25/254 (9%)
Query: 108 EEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVK 167
EE + + K ++++K E++ L ++ ++ +R+ K E E+E K
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQE--------LKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 168 RLLSTDAEAVSTRWEIIAEDETK------EAENQGLDISSPGMSGHRQGHDSLEHDELRE 221
+ E + + E I E E K + Q I RQ E +E R+
Sbjct: 348 --MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 222 --IFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQD---KLNESDEQHQENEGTNQ 276
++ E +++ + Q+EE + +LE +QD KL E +E+ QE E +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE---E 462
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENL-ALKNRFQAVLDELKQKEDREKEQ 335
+ +++I + K+QE +++ RQE L+ + E + + + +++ ++E++ +EQ
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 336 LSSLQEELESLLEK 349
+Q + E + E+
Sbjct: 523 EEKMQRQEEKMREQ 536
Score = 30.8 bits (68), Expect = 1.9
Identities = 22/99 (22%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 253 LERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENL 312
L ++LQ + Q +ENE N L ++++ + K+QE +++ QE I + E
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 313 ALK--NRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
+ + ++++++ED+ Q ++E+ E + E+
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 49.3 bits (116), Expect = 5e-06
Identities = 46/194 (23%), Positives = 96/194 (49%), Gaps = 16/194 (8%)
Query: 163 EKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHD-SLEHDELRE 221
++E K++L D E +S +I E+ + ++ M + S D+L +
Sbjct: 805 QEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSK 864
Query: 222 IFNDLSSS-SEDEDETQHQDEEDINIIDTEEDLERQLQ----DKLNESDEQHQENEGTNQ 276
+ + L +S SE E E Q +++ T ++L+ QLQ + L E E + E +
Sbjct: 865 VSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQL 336
++ ++++M+ +L + Q+ K+ E + + Q ++ELKQ +++K+Q+
Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKE---------EQQLQGNINELKQSSEQKKKQI 975
Query: 337 SSLQEELE-SLLEK 349
+LQ EL+ ++L+K
Sbjct: 976 EALQGELKIAVLQK 989
Score = 42.0 bits (97), Expect = 8e-04
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 17/127 (13%)
Query: 225 DLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQ-- 282
+L S E E E HQ + ++N + E+ ++ Q K NE +EQ + N+L +
Sbjct: 914 ELKKSLEKEKEASHQLKLELNSMQ-EQLIQAQNTLKQNEKEEQQLQGN-INELKQSSEQK 971
Query: 283 -KQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQE 341
KQI+ ++G+L+ I ++ L+N+ Q L + Q+ EKE++S LQ
Sbjct: 972 KKQIEALQGELK------------IAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQN 1019
Query: 342 ELESLLE 348
E E
Sbjct: 1020 NYEKSQE 1026
Score = 40.4 bits (93), Expect = 0.002
Identities = 67/282 (23%), Positives = 122/282 (43%), Gaps = 59/282 (20%)
Query: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIES--PDVEKEVKRL---LSTDAE 175
KK++D K ++ ++ KN++ +K + ++S E + R+ LS E
Sbjct: 313 KKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372
Query: 176 AVSTRWEIIAEDETK----------------EAENQGLDISSPGMSGHRQGHDSLE---- 215
A E ++E ETK E E GL + S H + ++
Sbjct: 373 ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGE 432
Query: 216 -HDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLER------QLQDKLNESDEQH 268
H L+E LSS + E Q D + + + EE L+ +LQ +L+++ +QH
Sbjct: 433 AHGRLKEQ-RQLSSEKLMDKEQQVADLQ-LKLSRLEEQLKEKVTNSTELQHQLDKTKQQH 490
Query: 269 QEN------------EGTNQLVMGIQK------QIDNMKGKLQETQDRA----KRQEDLI 306
QE E N L +++ +I N++ LQ++++ K +EDL
Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLY 550
Query: 307 MKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLE 348
K++ AVL++L++K +EQ++ L E+L++ E
Sbjct: 551 AKIQ---AGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSE 589
Score = 34.3 bits (77), Expect = 0.17
Identities = 35/167 (20%), Positives = 70/167 (41%), Gaps = 25/167 (14%)
Query: 207 HRQGHDSLEHDELRE-----------------IFNDLSSSSEDEDETQHQDEEDIN---- 245
H+Q ++L HD+++E N+L+S + E Q + I
Sbjct: 591 HKQAQENL-HDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTE 649
Query: 246 -IIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQED 304
++ E Q D N D + Q + I Q+D + KLQ+ Q+ + E
Sbjct: 650 LLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLES 709
Query: 305 LI--MKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
+ K + L+L+ + + + ++K+ E E +S ++ L+ L ++
Sbjct: 710 HLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQ 756
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 48.5 bits (114), Expect = 9e-06
Identities = 53/215 (24%), Positives = 100/215 (46%), Gaps = 36/215 (16%)
Query: 148 FRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSG- 206
F+ + + Y+E+ +EKE +R D E + ED + + GL S SG
Sbjct: 205 FKLSEMEAYLEN--IEKEEERKDDNDEEEEDIDF---FEDIDSDEDEGGLFGSKKLKSGK 259
Query: 207 ------HRQGHDSLEHDE-LREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQD 259
++ D +E DE + + +D S++++DE ++ E+++I +T+ED + Q
Sbjct: 260 SSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQ--- 316
Query: 260 KLNESDEQHQEN------------EGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIM 307
NE ++QH+E+ E + V+ ++K D +K + KRQE +
Sbjct: 317 -ENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFE------KRQEKMNE 369
Query: 308 KVENLALKNRFQAVLDELKQKEDREKEQLSSLQEE 342
K+ +L K + +L+ + +K +SL EE
Sbjct: 370 KIASLE-KELLEKKPWQLQGEVTAQKRPENSLLEE 403
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 48.5 bits (114), Expect = 9e-06
Identities = 51/219 (23%), Positives = 97/219 (44%), Gaps = 23/219 (10%)
Query: 140 LKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDI 199
+K + + K K E E+E+ + L T + ++ E +++++ L I
Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE----KSQSEYLKI 525
Query: 200 SSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDIN--IIDTEEDLERQL 257
S ++ +SL +EL + + SE++ Q+ E I++ E LE+ L
Sbjct: 526 SQ-----EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSL 580
Query: 258 QDKLNESDEQ--HQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALK 315
Q+ N+S + H E E K+I M K + + K Q+D + + LK
Sbjct: 581 QENKNQSKDLAVHLEAEKNKH-----NKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 635
Query: 316 NRFQAVLDELKQKEDREKEQLSS-----LQEELESLLEK 349
++Q +++L++K ++EKE L Q +E + EK
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEK 674
Score = 37.0 bits (84), Expect = 0.026
Identities = 30/139 (21%), Positives = 67/139 (48%), Gaps = 15/139 (10%)
Query: 226 LSSSSEDEDETQHQDEEDINII-DTEEDLERQLQDKLNESDEQHQENEGT--NQLVMGIQ 282
LSS + + +H+ EE+++++ D + ++++L+ K++E HQ+ + + + IQ
Sbjct: 689 LSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQ 748
Query: 283 KQIDNMKGKLQETQ----DRAKRQEDLIMKVENLALK--------NRFQAVLDELKQKED 330
+ +K ++ + + +R K ++ VENL + A LD + +
Sbjct: 749 RTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQS 808
Query: 331 REKEQLSSLQEELESLLEK 349
EQ + +E+L L +K
Sbjct: 809 ATHEQTKAYEEQLAQLQQK 827
Score = 34.3 bits (77), Expect = 0.17
Identities = 45/209 (21%), Positives = 92/209 (44%), Gaps = 36/209 (17%)
Query: 162 VEKEVKRLLSTDAEAV---STRWEIIAEDETKEAENQGL--------------DISSPGM 204
+E+++K + S+ +E + + + A E +EA++QG +++
Sbjct: 1691 LEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEK 1750
Query: 205 SGHRQGHDSLE----HDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDK 260
R G + E H E+R + + E + QH+D+ I + +E+LE + K
Sbjct: 1751 LLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHL--QEELEEK-NKK 1807
Query: 261 LNESDEQHQENEGTN---QLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNR 317
+ QH E EG Q ++ D+++ LQE + + E I ++++ ++
Sbjct: 1808 YSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQ- 1866
Query: 318 FQAVLDELKQKEDREKEQLSSLQEELESL 346
K+ E E+L+S E+L++L
Sbjct: 1867 --------KEVHRVEMEELTSKYEKLQAL 1887
Score = 33.9 bits (76), Expect = 0.22
Identities = 38/206 (18%), Positives = 87/206 (42%), Gaps = 24/206 (11%)
Query: 150 KTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQ 209
K KK+ +++ + R++ + EI + +E + NQ DI
Sbjct: 1508 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDI---------- 1557
Query: 210 GHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEE-DLERQLQDKLNESDEQH 268
EH EL + E++D + EE I ++ + ++ +L+ K E + +
Sbjct: 1558 -----EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVN 1612
Query: 269 QENEGTNQLVMGIQKQIDNMKG-KLQETQDRAKRQEDLI-------MKVENLALKNRFQA 320
+ + + ++ ++++ KL E + +A+++ I M+ + K ++
Sbjct: 1613 LSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1672
Query: 321 VLDELKQKEDREKEQLSSLQEELESL 346
L EL K + ++ L+E+L+S+
Sbjct: 1673 HLSELNTKLQEREREVHILEEKLKSV 1698
Score = 32.3 bits (72), Expect = 0.65
Identities = 57/305 (18%), Positives = 134/305 (43%), Gaps = 64/305 (20%)
Query: 100 DGDLYPPVEEPVASTDPKA---SKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAK--K 154
+G + V +P+ +P+A +K+++ + + + + G ++ ++R ++ K
Sbjct: 237 NGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLK 296
Query: 155 KYIESPDVEKEVKRLLSTDAEAVSTRWEIIAED-----------------ETKEAEN--- 194
+ E+ KE LL+++ EA+ + + ++ + ++A+N
Sbjct: 297 RCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIE 356
Query: 195 -----QGLDISSPGMSGHRQGHDSLEHDE-----LREIFNDLSSSSEDEDETQHQDE--- 241
+G+ I+ RQ H++LE E LR +++ E+ E + + E
Sbjct: 357 QLEQDKGMVIAET----KRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAA 412
Query: 242 -----EDINIIDTEEDLERQLQDKLNE--------SDEQH----QENEGTNQLVMGIQKQ 284
+ ++ E+ R+L+ +++E S+E+ QE Q V+ + K+
Sbjct: 413 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK 472
Query: 285 IDNMK-GKLQETQDR--AKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQE 341
+ KLQ+ ++ A+++++L K++ + FQ + +K E ++S +E
Sbjct: 473 SSEEQIAKLQKLHEKELARKEQELTKKLQTR--EREFQEQMKVALEKSQSEYLKISQEKE 530
Query: 342 ELESL 346
+ ESL
Sbjct: 531 QQESL 535
Score = 30.4 bits (67), Expect = 2.5
Identities = 27/124 (21%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Query: 234 DETQHQDEEDINIIDTE-EDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
+E + E +++ TE E L +L + L +H+ E + L K ++ K+
Sbjct: 669 EEMNEKTLEKLDVKQTELESLSSELSEVLKA---RHKLEEELSVLKDQTDKMKQELEAKM 725
Query: 293 QETQDRAKRQEDLIMKVENLALKNRFQAVLDE-------LKQKEDREKEQLSSLQEELES 345
E ++ ++Q D I+K ++++ +A+ D+ LK+++ KE + + E LE+
Sbjct: 726 DEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHV-ENLEA 784
Query: 346 LLEK 349
+++
Sbjct: 785 DIKR 788
Score = 30.0 bits (66), Expect = 3.2
Identities = 28/116 (24%), Positives = 60/116 (51%), Gaps = 15/116 (12%)
Query: 233 EDETQHQDEEDINIIDTEEDLER-QLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGK 291
E E Q +D + TE D + Q+QD + + ++Q+ E E Q V + + ++ K
Sbjct: 844 EVEAQKKD------VCTELDAHKIQVQDLMQQLEKQNSEME---QKVKSLTQVYES---K 891
Query: 292 LQETQDRAKRQEDLIMKVENLALKNR--FQAVLDELKQKEDREKEQLSSLQEELES 345
L++ ++ + ++++ EN+ L+ R + ++ L QK +++ + L EE E+
Sbjct: 892 LEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 947
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/239 (20%), Positives = 115/239 (48%), Gaps = 36/239 (15%)
Query: 108 EEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVK 167
EE + ++++K E++ IW + + ++ + RK +K + + + ++ +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM---HEQEEKIRKQEEKVWRQEEKIREQEE 524
Query: 168 RLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLS 227
++ + E + + E I E E E + + H Q + + +E R+
Sbjct: 525 KIREQE-EKMWRQEEKIREQEEMWREEEKM---------HEQ--EKIWEEEKRQ------ 566
Query: 228 SSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDN 287
E ED+ Q+E+ I + EE + RQ ++K+ E +E+ QE E + + +++I
Sbjct: 567 ---EQEDKMWRQEEK---IREQEEKVWRQ-EEKIREQEEKRQEQE---EKMWKQEEKIRE 616
Query: 288 MKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESL 346
+ K+QE +++ + QE+ I + E + Q +++ ++E++ EQ +QE+ E++
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEEMT-----QEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Score = 40.0 bits (92), Expect = 0.003
Identities = 36/191 (18%), Positives = 91/191 (47%), Gaps = 29/191 (15%)
Query: 120 KKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVST 179
++K +++E+K +W ++ + R+ +K+ + + K+ +++ + E +
Sbjct: 576 EEKIREQEEK-VWR----------QEEKIREQEEKRQEQEEKMWKQEEKIREQE-EKIQE 623
Query: 180 RWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQ 239
+ E I E E K E + + G ++ + ++++E ++ET +
Sbjct: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE-----------QEETMWR 672
Query: 240 DEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRA 299
EE I +E R+ ++K+ E +E QE E + + ++++ + K+QE +++
Sbjct: 673 QEEKIR---EQEKKIREQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQEQEEKM 726
Query: 300 KRQEDLIMKVE 310
+RQE+ + + E
Sbjct: 727 RRQEEKMWEQE 737
Score = 35.4 bits (80), Expect = 0.077
Identities = 30/138 (21%), Positives = 66/138 (47%), Gaps = 19/138 (13%)
Query: 231 EDEDETQHQDEEDINIIDTEEDLERQL--QDKLNESDEQHQENEGTNQL---------VM 279
E E++ + Q+E + +LE ++ Q+K+ E +E+ QE E + +
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 280 GIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED--------R 331
+++I + K++E + + RQE+ I + E + + + Q + +Q+E R
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 332 EKEQLSSLQEELESLLEK 349
+KE++ +E++ EK
Sbjct: 494 QKEKMHEQEEKIRKQEEK 511
Score = 33.1 bits (74), Expect = 0.38
Identities = 23/95 (24%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query: 251 EDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVE 310
+ L ++LQ + Q +ENE N+L ++++ + K+QE +++ + QE+ I + E
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 311 NLALKNRFQAVLDELKQKEDR--EKEQLSSLQEEL 343
+ + ++++++E+ EKE+ QEE+
Sbjct: 328 -----EKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 30/191 (15%)
Query: 186 EDETKEAENQGLDISSPGMSGHRQGHD---------SLEHDELREIFNDLSSSSED-EDE 235
E+E KE E + D+ + H Q + S + EI +L + D ED+
Sbjct: 952 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1011
Query: 236 TQHQDEEDINIIDTEEDLERQ----------------LQDKLNESDEQHQENEGTNQLVM 279
+ EE+ ++ E+L +Q ++ E E E T Q
Sbjct: 1012 LKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA 1071
Query: 280 GIQKQIDNMK-GKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSS 338
+Q ++D +K L+ ++ K +E ++ VEN ++ F+ ++ LKQ ++ +QLS+
Sbjct: 1072 KLQNELDTLKENNLKNVEELNKSKE--LLTVENQKMEE-FRKEIETLKQAAAQKSQQLSA 1128
Query: 339 LQEELESLLEK 349
LQEE L E+
Sbjct: 1129 LQEENVKLAEE 1139
Score = 37.0 bits (84), Expect = 0.026
Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 13/162 (8%)
Query: 185 AEDETKEAENQGLDISSPGMSGHR--QGHDSLEHDELREIFNDLSSSSED-EDETQHQDE 241
AE + K E + SS S R QG + L+ L+E +++S E E E Q E
Sbjct: 754 AEKQIKHLEIEKNAESSKASSITRELQGRE-LKLTNLQENLSEVSQVKETLEKELQILKE 812
Query: 242 EDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKR 301
+ + ++R +Q+ +N+ HQ+ E N L ++K +N+ + +++ +R
Sbjct: 813 KFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 869
Query: 302 QEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEEL 343
+E LI K + + + E+ + QL+ + +EL
Sbjct: 870 EEQLI------KAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 905
Score = 32.0 bits (71), Expect = 0.85
Identities = 45/190 (23%), Positives = 82/190 (43%), Gaps = 8/190 (4%)
Query: 159 SPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISS-PGMSGHRQGHDSLEHD 217
S D+EK + L D EA + E K E DI+ MSG + +D
Sbjct: 846 SSDLEKLRENL--ADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 903
Query: 218 ELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGT-NQ 276
ELR D+ E + + +E + + ED+ + + E+ ++H+E + +
Sbjct: 904 ELRLKERDVE---ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELER 960
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQL 336
+ ++K+++ + QE + R +R L+N + +LD + K +E+
Sbjct: 961 KLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLD-TEDKLKGAREEN 1019
Query: 337 SSLQEELESL 346
S L +ELE L
Sbjct: 1020 SGLLQELEEL 1029
Score = 30.4 bits (67), Expect = 2.5
Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 24/143 (16%)
Query: 214 LEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLE--------RQLQDKLNESD 265
L+ D LR+ ++ S + + E+ I ++ E++ E R+LQ + +
Sbjct: 728 LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLT 787
Query: 266 EQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDEL 325
+ +Q+ ++K++ +K K E + A ++++ Q +++L
Sbjct: 788 NLQENLSEVSQVKETLEKELQILKEKFAEASEEA------------VSVQRSMQETVNKL 835
Query: 326 KQKEDREKEQLSSLQEELESLLE 348
QKE EQ + L +LE L E
Sbjct: 836 HQKE----EQFNMLSSDLEKLRE 854
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 30/191 (15%)
Query: 186 EDETKEAENQGLDISSPGMSGHRQGHD---------SLEHDELREIFNDLSSSSED-EDE 235
E+E KE E + D+ + H Q + S + EI +L + D ED+
Sbjct: 987 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1046
Query: 236 TQHQDEEDINIIDTEEDLERQ----------------LQDKLNESDEQHQENEGTNQLVM 279
+ EE+ ++ E+L +Q ++ E E E T Q
Sbjct: 1047 LKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA 1106
Query: 280 GIQKQIDNMK-GKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSS 338
+Q ++D +K L+ ++ K +E ++ VEN ++ F+ ++ LKQ ++ +QLS+
Sbjct: 1107 KLQNELDTLKENNLKNVEELNKSKE--LLTVENQKMEE-FRKEIETLKQAAAQKSQQLSA 1163
Query: 339 LQEELESLLEK 349
LQEE L E+
Sbjct: 1164 LQEENVKLAEE 1174
Score = 37.0 bits (84), Expect = 0.026
Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 13/162 (8%)
Query: 185 AEDETKEAENQGLDISSPGMSGHR--QGHDSLEHDELREIFNDLSSSSED-EDETQHQDE 241
AE + K E + SS S R QG + L+ L+E +++S E E E Q E
Sbjct: 789 AEKQIKHLEIEKNAESSKASSITRELQGRE-LKLTNLQENLSEVSQVKETLEKELQILKE 847
Query: 242 EDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKR 301
+ + ++R +Q+ +N+ HQ+ E N L ++K +N+ + +++ +R
Sbjct: 848 KFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 904
Query: 302 QEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEEL 343
+E LI K + + + E+ + QL+ + +EL
Sbjct: 905 EEQLI------KAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 940
Score = 32.0 bits (71), Expect = 0.85
Identities = 45/190 (23%), Positives = 82/190 (43%), Gaps = 8/190 (4%)
Query: 159 SPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISS-PGMSGHRQGHDSLEHD 217
S D+EK + L D EA + E K E DI+ MSG + +D
Sbjct: 881 SSDLEKLRENL--ADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 938
Query: 218 ELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGT-NQ 276
ELR D+ E + + +E + + ED+ + + E+ ++H+E + +
Sbjct: 939 ELRLKERDVE---ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELER 995
Query: 277 LVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQL 336
+ ++K+++ + QE + R +R L+N + +LD + K +E+
Sbjct: 996 KLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLD-TEDKLKGAREEN 1054
Query: 337 SSLQEELESL 346
S L +ELE L
Sbjct: 1055 SGLLQELEEL 1064
Score = 30.4 bits (67), Expect = 2.5
Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 24/143 (16%)
Query: 214 LEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLE--------RQLQDKLNESD 265
L+ D LR+ ++ S + + E+ I ++ E++ E R+LQ + +
Sbjct: 763 LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLT 822
Query: 266 EQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDEL 325
+ +Q+ ++K++ +K K E + A ++++ Q +++L
Sbjct: 823 NLQENLSEVSQVKETLEKELQILKEKFAEASEEA------------VSVQRSMQETVNKL 870
Query: 326 KQKEDREKEQLSSLQEELESLLE 348
QKE EQ + L +LE L E
Sbjct: 871 HQKE----EQFNMLSSDLEKLRE 889
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 46.6 bits (109), Expect = 3e-05
Identities = 59/251 (23%), Positives = 102/251 (40%), Gaps = 32/251 (12%)
Query: 125 DKEKKFIWNHGITLPLKNVRKRRFRKTA----KKKYIESPDVEKEVKRLLSTDAEAVSTR 180
+KEK FI H PL ++ R R+ K +SP V+ + + E +
Sbjct: 897 EKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENL 956
Query: 181 WEIIAEDETKEAE--------NQGLDISSPGMSGHRQGHDSL--EHDELREIFNDLSSSS 230
+ E E K + + LD S ++ +SL E D+L DL +
Sbjct: 957 EKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGA 1016
Query: 231 EDEDETQHQDEEDINIIDTE-----------EDLERQLQDKLNESDEQHQENEGTNQLVM 279
E + E+ +D E EDL RQL++ + + + +NE +
Sbjct: 1017 ESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIE 1076
Query: 280 GIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQA------VLDELKQKEDREK 333
+Q ++ ++ E Q RAK D ++ E L + + + L+EL+ + +EK
Sbjct: 1077 TLQSNAKLLEVQILEVQ-RAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEK 1135
Query: 334 EQLSSLQEELE 344
+QL +ELE
Sbjct: 1136 KQLQKTMQELE 1146
Score = 35.8 bits (81), Expect = 0.059
Identities = 23/112 (20%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 235 ETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQE 294
E +++ +++ ++++++D + + + H+E E ++ + K+I+N+K +L
Sbjct: 84 EKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSH---INYVKEIENLKNELMA 140
Query: 295 TQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESL 346
R+K ED + L Q L E + ++ ++ + LQEE+E +
Sbjct: 141 V--RSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKI 190
Score = 35.8 bits (81), Expect = 0.059
Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 257 LQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQD--RAKRQEDLIMKVENLAL 314
L+ + N+S Q E EG Q ++ ID +K KLQ++Q+ + E ++ E+ L
Sbjct: 1331 LKQQKNKSMSQ-AETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTL 1389
Query: 315 KNRFQAVLDELKQKEDREKEQLSSLQEE 342
R +L E KE +E+L S+Q E
Sbjct: 1390 LERHNKMLQETVSKEAELREKLCSIQSE 1417
Score = 33.1 bits (74), Expect = 0.38
Identities = 54/280 (19%), Positives = 130/280 (46%), Gaps = 42/280 (15%)
Query: 109 EPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKR 168
+P++S K ++ +KE K + L V+ ++ +++K E+ V++E++
Sbjct: 941 DPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRK---ETQTVKEELES 997
Query: 169 LLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEH---DELREIFND 225
L S + ++ ++I E+ + + S + ++ ++ EH D R++ N
Sbjct: 998 LRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNS 1057
Query: 226 L----SSSSEDED-----ETQHQDEE--DINIIDTEED---LERQLQDKLNESDEQHQEN 271
+ +S++ED ET + + ++ I++ + ++++L+ + + +++ +E+
Sbjct: 1058 TLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEH 1117
Query: 272 EGTNQLVMGIQKQIDNMKGKLQETQDRAK-----RQEDLIMKVE-----------NLALK 315
T + +Q Q+ K +LQ+T + Q+ +M +E N L
Sbjct: 1118 ATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLT 1177
Query: 316 NRFQAVLD---ELK---QKEDREKEQLSSLQEELESLLEK 349
N+ + D E+K QK++ +E+++SLQ ++ EK
Sbjct: 1178 NKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK 1217
Score = 29.6 bits (65), Expect = 4.2
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 11/147 (7%)
Query: 207 HRQGHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDE 266
H + SL+ +EI S +E ++E + ++ + L+ Q ++ E E
Sbjct: 422 HNREVQSLKEQHQKEI------SELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQE 475
Query: 267 QHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRF--QAVLDE 324
E +++ +Q ++ GK+ + + K+Q+ + L+ F + L E
Sbjct: 476 AILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLE 535
Query: 325 LKQKEDREKEQLSSLQE---ELESLLE 348
+ E E+L S QE ELE+ ++
Sbjct: 536 TVNRLQGENEKLLSQQELVPELENTIK 562
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 45.8 bits (107), Expect = 6e-05
Identities = 33/123 (26%), Positives = 65/123 (52%), Gaps = 20/123 (16%)
Query: 231 EDEDETQHQDEE---DINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQK-QID 286
E E+E Q Q+E+ I +E R+ ++K+ E +E QE E MG Q+ ++
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK----MGEQEGKMC 477
Query: 287 NMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESL 346
+ K+QE +++ +RQE+ I + E +++++E++ +EQ +QE+ E +
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEK------------KIREQEEKIREQEEMMQEQEEKM 525
Query: 347 LEK 349
E+
Sbjct: 526 WEQ 528
Score = 43.5 bits (101), Expect = 3e-04
Identities = 43/218 (19%), Positives = 107/218 (49%), Gaps = 14/218 (6%)
Query: 137 TLPLKNVRKRRFRKTAKKKYIESPDVE-----KEVKRLLSTDAEAVSTRWEIIAEDETKE 191
T+ + ++++ + K + +ES E KE+KR L A+ + + ++ AE +
Sbjct: 201 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER-AKLLLPQQQLQAEADHLG 259
Query: 192 AENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEE 251
E Q + + + L + +++ E E++ Q Q+E+ I + EE
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK---IREQEE 316
Query: 252 DLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVEN 311
+ RQ ++ + E +E+ + E +++ +++I ++ K+ E Q++ + QE+ + E
Sbjct: 317 KMRRQ-EEMMWEKEEKMRRQE---EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEK 371
Query: 312 LALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
+ + + Q ++ ++E++ +EQ ++E+ E + E+
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/242 (19%), Positives = 105/242 (43%), Gaps = 31/242 (12%)
Query: 108 EEPVASTDPKASKKKDK-DKEKKFIWNHGITLPLKNV----RKRRFRKTAKKKYIESPDV 162
EE + + K ++++K ++++ +W + + ++ + R+ +K + +
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 163 EKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREI 222
E+E KR R E A+ +E + + + Q + ++ ++
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 223 FNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQ 282
+ E E++ + Q+E+ I +E R+ ++K+ E +E QE E MG Q
Sbjct: 421 WEQEEEMQEQEEKMRRQEEK----IREQEKKIREQEEKIREQEEMMQEQEEK----MGEQ 472
Query: 283 K-QIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQE 341
+ ++ + K+QE +++ +RQE+ I + E K+ RE+E+ QE
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQE-----------------KKIREQEEKIREQE 515
Query: 342 EL 343
E+
Sbjct: 516 EM 517
Score = 38.5 bits (88), Expect = 0.009
Identities = 38/182 (20%), Positives = 83/182 (45%), Gaps = 29/182 (15%)
Query: 153 KKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHD 212
++K E + +E + + E + + + I E E K E + + G ++G
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG-- 474
Query: 213 SLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENE 272
++ + E E++ + Q+E+ I +E R+ ++K+ E +E QE E
Sbjct: 475 --------KMCEQEAKMQEQEEKMRRQEEK----IREQEKKIREQEEKIREQEEMMQEQE 522
Query: 273 GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDRE 332
+ + ++++ + K+QE +++ +RQE+ K R Q V L+Q+E++
Sbjct: 523 ---EKMWEQEEKMCEQEEKMQEQEEKMRRQEE----------KMREQEV--RLRQQEEKM 567
Query: 333 KE 334
+E
Sbjct: 568 QE 569
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 45.8 bits (107), Expect = 6e-05
Identities = 34/170 (20%), Positives = 84/170 (49%), Gaps = 20/170 (11%)
Query: 200 SSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTE----EDLER 255
S ++G +Q HD + +EL++ ++L++++ ++ + ++N + E E+ R
Sbjct: 1345 SCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKAR 1404
Query: 256 QLQDKLNES-----------DEQHQENEGTNQLVMGIQKQIDNMKGK----LQETQDRAK 300
L+DKL+E+ + + Q +G +Q + + +Q++ GK +QE D K
Sbjct: 1405 LLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKK 1464
Query: 301 RQEDLIMKVENL-ALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
+ + +++E+L K + Q +D + + ++ + L ++ S ++
Sbjct: 1465 IKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDE 1514
Score = 37.7 bits (86), Expect = 0.015
Identities = 31/142 (21%), Positives = 70/142 (49%), Gaps = 16/142 (11%)
Query: 215 EHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLE-----RQLQDKLNESDEQHQ 269
+ + E + ++E+E Q ++ EDI++ + E R+L+ + E + +
Sbjct: 1153 QKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAER 1212
Query: 270 ENEGTNQLVM-------GIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQA-- 320
E E QL + +++ + N + +L+E + ED + K ++L+L + Q
Sbjct: 1213 ELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHL-KRKDLSLNDLEQQKN 1271
Query: 321 -VLDELKQKEDREKEQLSSLQE 341
+++EL++K D E+E L +++
Sbjct: 1272 KLMEELRRKRDNEEELLKLIKQ 1293
Score = 37.0 bits (84), Expect = 0.026
Identities = 46/206 (22%), Positives = 90/206 (43%), Gaps = 26/206 (12%)
Query: 154 KKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSG------- 206
K+ +E + +L+ +A S I+ E +T + + L I + G
Sbjct: 1573 KQKVEELTRQNNETKLMMQRIQAESEN--IVLEKQTIQQRCEALKIQADGFKDQLRSTNE 1630
Query: 207 HRQGHDSLEHDELREIF---NDLSSSSEDEDETQHQ-DEEDINIIDTEEDLERQLQDKLN 262
H E D R+I DL+ S E + + D+++I I +T++++ R L +LN
Sbjct: 1631 HLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEV-RNLNAELN 1689
Query: 263 ESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVL 322
S E+ + E QL Q Q+ + +L++ QD +L +K + +R +
Sbjct: 1690 ASKEEKRRGEQKVQLQ---QAQVQELNNRLKKVQD------ELHLKTIEEQMTHRKMVLF 1740
Query: 323 DELKQKEDREKEQLSSLQEELESLLE 348
E + + K+ ++++E L+E
Sbjct: 1741 QE---ESGKFKQSAEEFRKKMEKLME 1763
Score = 36.6 bits (83), Expect = 0.034
Identities = 26/119 (21%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Query: 231 EDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKG 290
ED E+Q DI ++ E ++ +Q +L +S E+ ++ E L + ++ N++
Sbjct: 695 EDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYI---SEVRNIRL 751
Query: 291 KLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK 349
+L+ +DR RQ ++ ++L ++LK++ +R K+ L ++ + E +
Sbjct: 752 RLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITNKCEEFFSQ 810
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 45.8 bits (107), Expect = 6e-05
Identities = 53/243 (21%), Positives = 106/243 (43%), Gaps = 28/243 (11%)
Query: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKY----------IESPDVEK-EVKRL 169
K+ +D K + + + +N+RK R TA+ Y I S D E E+ L
Sbjct: 484 KEIEDLRAKLLESEAVN---ENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 540
Query: 170 LSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSG-HRQGHDSLEHDELREIFNDLSS 228
D E + + + + + +N D G + ++ LE +E +E+ S
Sbjct: 541 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEV-----S 595
Query: 229 SSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGI-QKQIDN 287
EDE+E + ++E+DI+ ++ ++ + + +K N +Q + + I QK ID
Sbjct: 596 DHEDEEEEEEEEEDDIDGGESSDESDSESDEKAN-----YQADLANITCEIAIKQKLIDE 650
Query: 288 MKGKLQETQDRAKRQEDLIMKVENLALKNRFQ--AVLDELKQKEDREKEQLSSLQEELES 345
++ + Q K+ E+ +M +++ + + VL L E +E+ ++ E E
Sbjct: 651 LENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEK 710
Query: 346 LLE 348
L+
Sbjct: 711 KLQ 713
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 45.4 bits (106), Expect = 7e-05
Identities = 46/213 (21%), Positives = 89/213 (41%), Gaps = 28/213 (13%)
Query: 140 LKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIA--------EDETKE 191
L N +R K K ES K + +L + E E+I E K
Sbjct: 2146 LANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKR 2205
Query: 192 AENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEE 251
+ SS + H S E + L + S S +E+E + EE
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEER------------EE 2253
Query: 252 DLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVEN 311
+ ER+ ++ E +E+ +E EG + V +++ + K K ++ ++ + +E++ + E
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVE--KEEEEKKKKKKEKKKEEVQEKEEVFEEKEE 2311
Query: 312 LALKNRFQAVLDELKQKEDREKEQLSSLQEELE 344
+ + +++ DE E+E+ SL+EE++
Sbjct: 2312 IMSEEETESLSDE------EEEEESCSLEEEVD 2338
Score = 36.6 bits (83), Expect = 0.034
Identities = 31/139 (22%), Positives = 62/139 (44%), Gaps = 5/139 (3%)
Query: 158 ESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHD 217
ES E+E +R + E R E E +E E + ++ ++ E
Sbjct: 2241 ESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300
Query: 218 ELREIFNDLSS-SSEDEDETQHQDEEDINIIDTEEDLERQLQ----DKLNESDEQHQENE 272
E E+F + SE+E E+ +EE+ EE+++R+ + +K + EQ +++
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSL 2360
Query: 273 GTNQLVMGIQKQIDNMKGK 291
+ V+ I + + + KG+
Sbjct: 2361 RGRERVLSILRGVPHGKGR 2379
Score = 32.0 bits (71), Expect = 0.85
Identities = 45/193 (23%), Positives = 71/193 (36%), Gaps = 30/193 (15%)
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D E V+ E+ E E KE + Q H EH R + +
Sbjct: 1540 DEEEVTLEEEVSREGEEKEQQVT-----------EEQRHIQEEHKWARIHRKRARAEKKR 1588
Query: 233 EDETQHQDEEDINIIDTEEDL---ERQLQD---KLNESDEQHQENEGT------------ 274
E + +E+ + E L ER+L K+ + D + + EG
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648
Query: 275 NQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLA-LKNRFQAVLDELKQKEDREK 333
+L +K K ++ + A+ +E L K LA +KN ++EL Q+E
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708
Query: 334 EQLSSLQEELESL 346
Q L +ELE L
Sbjct: 1709 WQEKELAQELEEL 1721
>gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens]
Length = 348
Score = 45.4 bits (106), Expect = 7e-05
Identities = 54/242 (22%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Query: 123 DKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWE 182
DK E + +++ L N+R TAK + ++ ++E++R + + + W+
Sbjct: 16 DKTNESALVKEKELSIELANIRDEVAFHTAKCEKLQKE--KEELERRFEDEVKRLG--WQ 71
Query: 183 IIAEDETKEAENQGLDISSPGMSGHRQGHDSL-----EHDELREIFNDLSSSSEDEDETQ 237
AE + E Q L + + D L +H E E DL++S D +
Sbjct: 72 QQAELQELEERLQ-LQFEAEMARLQEEHGDQLLSIRCQHQEQVE---DLTAS-HDAALLE 126
Query: 238 HQDEEDINIIDTEEDLERQLQDKLNESDEQHQE-NEGTNQLVMGIQKQIDNMKGKLQETQ 296
++ + I ++D + ++Q+ ++ + + +E E +L + +Q Q+D + + Q +
Sbjct: 127 MENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLR 186
Query: 297 DRAKRQEDLIMKVEN------LALKNRFQAVLDELKQKEDREKEQLSSLQE---ELESLL 347
DRA+R E+ + K LA + + LKQ + + +Q+ ++ ELE L
Sbjct: 187 DRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLA 246
Query: 348 EK 349
EK
Sbjct: 247 EK 248
Score = 33.9 bits (76), Expect = 0.22
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 28/156 (17%)
Query: 214 LEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDE------Q 267
LE EL E F L S +D+ +T + + D E L+ E E Q
Sbjct: 155 LEKKELEENFEKLRLSLQDQVDTLTFQSQSLR--DRARRFEEALRKNTEEQLEIALAPYQ 212
Query: 268 HQENE--GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDL-----IMKVENLALKNRFQ- 319
H E + Q++ +QI + K+ E + A++ L +++ +N LK R
Sbjct: 213 HLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQ 272
Query: 320 ------------AVLDELKQKEDREKEQLSSLQEEL 343
A L E +KE +EK++LS EEL
Sbjct: 273 NTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 308
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 200 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 252
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 253 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 299
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 300 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 359
Query: 293 QETQD 297
+E ++
Sbjct: 360 EEAEE 364
Score = 34.7 bits (78), Expect = 0.13
Identities = 48/254 (18%), Positives = 102/254 (40%), Gaps = 35/254 (13%)
Query: 117 KASKKKDKDKEKKFIWNHGIT-------LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL 169
KA ++ ++ K ++ H L K R+R+ R+ K++ + + +R
Sbjct: 131 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERR 190
Query: 170 LSTDAEA-VSTRWEIIAEDETKEAENQGLDISSPGMSGHR----QGHDSLEHDEL--REI 222
+A VS + ED + + + S P R G ++ +++ R++
Sbjct: 191 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 250
Query: 223 FNDLSSSSEDEDETQH------------QDEEDINIIDTEEDLERQLQDKLNESDEQHQE 270
+DL S+ E +T ++EE+ + EE + ++ E +E+ +E
Sbjct: 251 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 310
Query: 271 NEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED 330
G+N Q + + ++ E ++R L++ ++RF E ++ E+
Sbjct: 311 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP------ESRFDRDSGESEEAEE 364
Query: 331 REKE---QLSSLQE 341
E Q S+L E
Sbjct: 365 EVGEGTPQSSALTE 378
Score = 30.4 bits (67), Expect = 2.5
Identities = 37/250 (14%), Positives = 94/250 (37%), Gaps = 26/250 (10%)
Query: 108 EEPVASTDPKASKKKDK-----DKEKKFIWNHGITLPLKNVRKRRFR----------KTA 152
++ +A P+ +K+K D+++K W H ++ R++R R +
Sbjct: 80 DDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQ 139
Query: 153 KKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHD 212
K++ + +E RL + + R + E +E + + +
Sbjct: 140 KRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREV 199
Query: 213 SLEHDELREIFNDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENE 272
S H +RE ++D +S E + D + ++ + ++ + + ++
Sbjct: 200 SAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 259
Query: 273 GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDRE 332
+ ++ G +E ++ + +E+ E+ +E +++E+ E
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-----------EEEEEEEEEE 308
Query: 333 KEQLSSLQEE 342
+E+ S EE
Sbjct: 309 EEETGSNSEE 318
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 210 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 262
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 263 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 309
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 310 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 369
Query: 293 QETQD 297
+E ++
Sbjct: 370 EEAEE 374
Score = 34.7 bits (78), Expect = 0.13
Identities = 48/254 (18%), Positives = 102/254 (40%), Gaps = 35/254 (13%)
Query: 117 KASKKKDKDKEKKFIWNHGIT-------LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL 169
KA ++ ++ K ++ H L K R+R+ R+ K++ + + +R
Sbjct: 141 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERR 200
Query: 170 LSTDAEA-VSTRWEIIAEDETKEAENQGLDISSPGMSGHR----QGHDSLEHDEL--REI 222
+A VS + ED + + + S P R G ++ +++ R++
Sbjct: 201 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 260
Query: 223 FNDLSSSSEDEDETQH------------QDEEDINIIDTEEDLERQLQDKLNESDEQHQE 270
+DL S+ E +T ++EE+ + EE + ++ E +E+ +E
Sbjct: 261 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 320
Query: 271 NEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED 330
G+N Q + + ++ E ++R L++ ++RF E ++ E+
Sbjct: 321 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP------ESRFDRDSGESEEAEE 374
Query: 331 REKE---QLSSLQE 341
E Q S+L E
Sbjct: 375 EVGEGTPQSSALTE 388
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 201 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 253
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 254 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 300
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 301 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 360
Query: 293 QETQD 297
+E ++
Sbjct: 361 EEAEE 365
Score = 34.7 bits (78), Expect = 0.13
Identities = 48/254 (18%), Positives = 102/254 (40%), Gaps = 35/254 (13%)
Query: 117 KASKKKDKDKEKKFIWNHGIT-------LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL 169
KA ++ ++ K ++ H L K R+R+ R+ K++ + + +R
Sbjct: 132 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERR 191
Query: 170 LSTDAEA-VSTRWEIIAEDETKEAENQGLDISSPGMSGHR----QGHDSLEHDEL--REI 222
+A VS + ED + + + S P R G ++ +++ R++
Sbjct: 192 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 251
Query: 223 FNDLSSSSEDEDETQH------------QDEEDINIIDTEEDLERQLQDKLNESDEQHQE 270
+DL S+ E +T ++EE+ + EE + ++ E +E+ +E
Sbjct: 252 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 311
Query: 271 NEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED 330
G+N Q + + ++ E ++R L++ ++RF E ++ E+
Sbjct: 312 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP------ESRFDRDSGESEEAEE 365
Query: 331 REKE---QLSSLQE 341
E Q S+L E
Sbjct: 366 EVGEGTPQSSALTE 379
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 210 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 262
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 263 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 309
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 310 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 369
Query: 293 QETQD 297
+E ++
Sbjct: 370 EEAEE 374
Score = 33.9 bits (76), Expect = 0.22
Identities = 44/226 (19%), Positives = 92/226 (40%), Gaps = 28/226 (12%)
Query: 138 LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEA-VSTRWEIIAEDETKEAENQG 196
L K R+R+ R+ K++ + + +R +A VS + ED + + +
Sbjct: 169 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASH 228
Query: 197 LDISSPGMSGHR----QGHDSLEHDEL--REIFNDLSSSSEDEDETQH------------ 238
S P R G ++ +++ R++ +DL S+ E +T
Sbjct: 229 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288
Query: 239 QDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDR 298
++EE+ + EE + ++ E +E+ +E G+N Q + + ++ E ++R
Sbjct: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348
Query: 299 AKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKE---QLSSLQE 341
L++ ++RF E ++ E+ E Q S+L E
Sbjct: 349 ENENHLLVVP------ESRFDRDSGESEEAEEEVGEGTPQSSALTE 388
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 178 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 230
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 231 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 277
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 278 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 337
Query: 293 QETQD 297
+E ++
Sbjct: 338 EEAEE 342
Score = 34.7 bits (78), Expect = 0.13
Identities = 48/254 (18%), Positives = 102/254 (40%), Gaps = 35/254 (13%)
Query: 117 KASKKKDKDKEKKFIWNHGIT-------LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL 169
KA ++ ++ K ++ H L K R+R+ R+ K++ + + +R
Sbjct: 109 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERR 168
Query: 170 LSTDAEA-VSTRWEIIAEDETKEAENQGLDISSPGMSGHR----QGHDSLEHDEL--REI 222
+A VS + ED + + + S P R G ++ +++ R++
Sbjct: 169 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 228
Query: 223 FNDLSSSSEDEDETQH------------QDEEDINIIDTEEDLERQLQDKLNESDEQHQE 270
+DL S+ E +T ++EE+ + EE + ++ E +E+ +E
Sbjct: 229 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 288
Query: 271 NEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED 330
G+N Q + + ++ E ++R L++ ++RF E ++ E+
Sbjct: 289 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP------ESRFDRDSGESEEAEE 342
Query: 331 REKE---QLSSLQE 341
E Q S+L E
Sbjct: 343 EVGEGTPQSSALTE 356
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 167 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 219
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 220 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 266
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 267 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 326
Query: 293 QETQD 297
+E ++
Sbjct: 327 EEAEE 331
Score = 34.7 bits (78), Expect = 0.13
Identities = 48/254 (18%), Positives = 102/254 (40%), Gaps = 35/254 (13%)
Query: 117 KASKKKDKDKEKKFIWNHGIT-------LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL 169
KA ++ ++ K ++ H L K R+R+ R+ K++ + + +R
Sbjct: 98 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERR 157
Query: 170 LSTDAEA-VSTRWEIIAEDETKEAENQGLDISSPGMSGHR----QGHDSLEHDEL--REI 222
+A VS + ED + + + S P R G ++ +++ R++
Sbjct: 158 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 217
Query: 223 FNDLSSSSEDEDETQH------------QDEEDINIIDTEEDLERQLQDKLNESDEQHQE 270
+DL S+ E +T ++EE+ + EE + ++ E +E+ +E
Sbjct: 218 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 277
Query: 271 NEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED 330
G+N Q + + ++ E ++R L++ ++RF E ++ E+
Sbjct: 278 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP------ESRFDRDSGESEEAEE 331
Query: 331 REKE---QLSSLQE 341
E Q S+L E
Sbjct: 332 EVGEGTPQSSALTE 345
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 113 STDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLST 172
S + ++ DK K W+ P + RF +K ++ EK +R L +
Sbjct: 212 SAHHRTMREDYSDKVKASHWSRSPPRP----PRERFELGDGRKPVKE---EKMEERDLLS 264
Query: 173 DAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSED 232
D + +S +E +T AE+ + S G + E +E E +S +
Sbjct: 265 DLQDISD-----SERKTSSAESSSAESGS--------GSEEEEEEEEEEEEEGSTSEESE 311
Query: 233 EDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKL 292
E+E + ++EE+ ++EE E+ ++ E + +E E N L++ + + D G+
Sbjct: 312 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 371
Query: 293 QETQD 297
+E ++
Sbjct: 372 EEAEE 376
Score = 34.7 bits (78), Expect = 0.13
Identities = 48/254 (18%), Positives = 102/254 (40%), Gaps = 35/254 (13%)
Query: 117 KASKKKDKDKEKKFIWNHGIT-------LPLKNVRKRRFRKTAKKKYIESPDVEKEVKRL 169
KA ++ ++ K ++ H L K R+R+ R+ K++ + + +R
Sbjct: 143 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERR 202
Query: 170 LSTDAEA-VSTRWEIIAEDETKEAENQGLDISSPGMSGHR----QGHDSLEHDEL--REI 222
+A VS + ED + + + S P R G ++ +++ R++
Sbjct: 203 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 262
Query: 223 FNDLSSSSEDEDETQH------------QDEEDINIIDTEEDLERQLQDKLNESDEQHQE 270
+DL S+ E +T ++EE+ + EE + ++ E +E+ +E
Sbjct: 263 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 322
Query: 271 NEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKED 330
G+N Q + + ++ E ++R L++ ++RF E ++ E+
Sbjct: 323 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP------ESRFDRDSGESEEAEE 376
Query: 331 REKE---QLSSLQE 341
E Q S+L E
Sbjct: 377 EVGEGTPQSSALTE 390
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/183 (19%), Positives = 85/183 (46%), Gaps = 11/183 (6%)
Query: 166 VKRLLSTDAEAVSTRWEIIAEDET--KEAENQGLDISSPGMSGHRQGHDSLEHDELREIF 223
++RLL+ EA T W+ + +++ E G + + Q DSL + +
Sbjct: 189 LQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQA---CSKNQTEDSLRKELIALQE 245
Query: 224 NDLSSSSEDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQK 283
+ + + ++ + +E I ++ ++ER L + +E + NE T + + +
Sbjct: 246 DKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELAN 305
Query: 284 QIDNMKGKLQETQDRAK----RQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSL 339
+ + ++++ D+ K +QE++ K + A K Q +DE+++KE + ++ +L
Sbjct: 306 KYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQ--AEKKELQHKIDEMEEKEQELQAKIEAL 363
Query: 340 QEE 342
Q +
Sbjct: 364 QAD 366
Score = 38.1 bits (87), Expect = 0.012
Identities = 54/221 (24%), Positives = 95/221 (42%), Gaps = 40/221 (18%)
Query: 163 EKEVKRLLSTDAEAVSTRWEIIA--EDETKEAENQGLDISS---------PGMSGHRQGH 211
E++ + ST E +S R EI+ + K A + DI+S + R+
Sbjct: 547 EEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAA 606
Query: 212 DSLEHD--ELREIFNDLSSSSED---EDETQHQDE-----EDINIIDTE----------- 250
E + L+ F ED E+ T+ Q E ++ N ++TE
Sbjct: 607 SEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLL 666
Query: 251 -EDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQ-EDLIMK 308
+L+RQ + +L+ S +Q E ++ +K+++N G L+E R + L+ K
Sbjct: 667 SSELQRQ-EKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSK 725
Query: 309 VENLALK-----NRFQAVLDELKQKEDREKEQLSSLQEELE 344
EN A + Q VL ELK K + +++ S+ +EL+
Sbjct: 726 AENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELK 766
Score = 32.7 bits (73), Expect = 0.50
Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 234 DETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQ 293
D ++E+D I T ++L + L + + + +Q+++ ++ +L+
Sbjct: 541 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE 600
Query: 294 ETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESL 346
+ A E E +L+N FQ +Q ED+++E+ + LQ ELE L
Sbjct: 601 RWRKAASEYEK-----EITSLQNSFQL---RCQQCEDQQREEATRLQGELEKL 645
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 44.7 bits (104), Expect = 1e-04
Identities = 51/233 (21%), Positives = 104/233 (44%), Gaps = 41/233 (17%)
Query: 126 KEKKFIWNHGITLPLKNVRKRRFRKTA-------KKKYIESPDVEKEVKRLLSTDAEAVS 178
+EK+ +T LKN RK R A +K+ +ES ++++E + L +AE
Sbjct: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
Query: 179 TR--WEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEDET 236
R E E KE E + + Q H+ ++ +RE + +
Sbjct: 604 VRKAEEERLRQEAKEREKERI----------LQEHEQIKKKTVRERLEQIKKTELGAKAF 653
Query: 237 QHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQ 296
+ D ED+ +D + + +Q++ E E +Q+++ N + K+ +
Sbjct: 654 KDIDIEDLEELDPDFIMAKQVEQLEKEKKE--------------LQERLKNQEKKI-DYF 698
Query: 297 DRAKRQEDLIMKVENLALKNRFQAV-LDELKQKEDREKEQLSSLQEELESLLE 348
+RAKR E++ + +K+ ++ + ++ E +E+E+++++Q E E LE
Sbjct: 699 ERAKRLEEIPL------IKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALE 745
Score = 32.3 bits (72), Expect = 0.65
Identities = 44/256 (17%), Positives = 107/256 (41%), Gaps = 25/256 (9%)
Query: 109 EPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKR 168
+ V + + +++ K++EK+ I + K VR+R + K + + +++
Sbjct: 602 QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRER-LEQIKKTELGAKAFKDIDIED 660
Query: 169 LLSTDAEAVSTRWEIIAEDETKEAENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSS 228
L D + + + E E KE + + + + D E + E + S
Sbjct: 661 LEELDPDFIMAKQVEQLEKEKKELQER--------LKNQEKKIDYFERAKRLEEIPLIKS 712
Query: 229 SSEDE-----DETQHQDEEDINIIDTEEDLERQLQDKLNESDEQH----------QENEG 273
+ E++ D + Q+EE I + E + + +++++ E +++
Sbjct: 713 AYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY 772
Query: 274 TNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREK 333
+L ++ + +L+E + R +++E I + + +A LK++E+RE+
Sbjct: 773 EEKLKQFEERLAEERHNRLEERK-RQRKEERRITYYREKEEEEQRRAEEQMLKEREERER 831
Query: 334 EQLSSLQEELESLLEK 349
+ + +EEL E+
Sbjct: 832 AERAKREEELREYQER 847
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,108,774
Number of Sequences: 37866
Number of extensions: 612780
Number of successful extensions: 8236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 847
Number of HSP's that attempted gapping in prelim test: 4549
Number of HSP's gapped (non-prelim): 3033
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.