BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precursor [Homo sapiens] (818 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precurs... 1619 0.0 gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precurs... 1605 0.0 gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 595 e-170 gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 595 e-170 gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 595 e-170 gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 595 e-170 gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 587 e-167 gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 587 e-167 gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 583 e-166 gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 583 e-166 gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 579 e-165 gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 579 e-165 gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 575 e-164 gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs... 575 e-164 gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 574 e-163 gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 574 e-163 gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 572 e-163 gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso... 572 e-163 gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 571 e-163 gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs... 571 e-163 gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 570 e-162 gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 570 e-162 gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precurs... 567 e-161 gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 567 e-161 gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 563 e-160 gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs... 563 e-160 gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs... 563 e-160 gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 563 e-160 gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 562 e-160 gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 562 e-160 >gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precursor [Homo sapiens] Length = 818 Score = 1619 bits (4193), Expect = 0.0 Identities = 818/818 (100%), Positives = 818/818 (100%) Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS Sbjct: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN Sbjct: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS Sbjct: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT Sbjct: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG Sbjct: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 Query: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA Sbjct: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360 Query: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS Sbjct: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420 Query: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV Sbjct: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480 Query: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT Sbjct: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540 Query: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI Sbjct: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600 Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV Sbjct: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660 Query: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR Sbjct: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720 Query: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL Sbjct: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 Query: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAMVSKFYGI 818 RNLATGVGLNLPISCIQIRNRKGDHANVNAMVSKFYGI Sbjct: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAMVSKFYGI 818 >gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precursor [Homo sapiens] Length = 963 Score = 1605 bits (4157), Expect = 0.0 Identities = 811/811 (100%), Positives = 811/811 (100%) Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS Sbjct: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN Sbjct: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS Sbjct: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT Sbjct: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG Sbjct: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 Query: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA Sbjct: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360 Query: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS Sbjct: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420 Query: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV Sbjct: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480 Query: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT Sbjct: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540 Query: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI Sbjct: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600 Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV Sbjct: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660 Query: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR Sbjct: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720 Query: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL Sbjct: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 Query: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAM 811 RNLATGVGLNLPISCIQIRNRKGDHANVNAM Sbjct: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAM 811 >gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor [Homo sapiens] Length = 936 Score = 595 bits (1535), Expect = e-170 Identities = 323/710 (45%), Positives = 449/710 (63%), Gaps = 8/710 (1%) Query: 5 GVAVLCLW--VSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHR 62 G+ +LCL+ + A A Q+ YS+PEE E+G VGN+S DL L ++ R R +S R Sbjct: 16 GLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75 Query: 63 ELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSP 122 F ++ SG+L+ DRE+LC A CV+++++++ED ++L I I V D NDN+P Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135 Query: 123 LFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEY 182 F A ++ + I E + G RF LP A D D G N + SY LSP++HF L + SR +G +Y Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195 Query: 183 PELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKV 242 PELVLE +LDRE+ A H LVLTA DGG P RSG V++ V D NDNAPVF YR V Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255 Query: 243 PETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPP 302 PE P GT L V A D DEG+NGEV YS +L +F ++ +GE++++ +L Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLL-KFQLNKYTGEIKISENLDYE 314 Query: 303 ET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIAL 361 ET E I+A D G + +TAK+L+ V DVND++PEL +L +PV ED+ GTV+AL Sbjct: 315 ETGFYEIEIQAEDGGAY--LATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372 Query: 362 FSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSG 421 +V D D + NG+V C + + PF+L S D+YY L+I LDREQ+S Y + +TA+D G Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432 Query: 422 SPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVS 481 SPPLST + VAD+NDN P F Q ++ ENN GAS+ V A DPD +N + Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492 Query: 482 YELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTI 541 Y L + +G SS +++ S +G + A SFD+EQ QV D G PP S+ V++ Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552 Query: 542 NLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600 +LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612 Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660 +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+ Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672 Query: 661 PQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ 709 PQ+L D P + S LYLV+A+A +S +FL ++ + +L + Sbjct: 673 PQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRR 722 >gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor [Homo sapiens] Length = 850 Score = 595 bits (1535), Expect = e-170 Identities = 323/710 (45%), Positives = 449/710 (63%), Gaps = 8/710 (1%) Query: 5 GVAVLCLW--VSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHR 62 G+ +LCL+ + A A Q+ YS+PEE E+G VGN+S DL L ++ R R +S R Sbjct: 16 GLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75 Query: 63 ELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSP 122 F ++ SG+L+ DRE+LC A CV+++++++ED ++L I I V D NDN+P Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135 Query: 123 LFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEY 182 F A ++ + I E + G RF LP A D D G N + SY LSP++HF L + SR +G +Y Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195 Query: 183 PELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKV 242 PELVLE +LDRE+ A H LVLTA DGG P RSG V++ V D NDNAPVF YR V Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255 Query: 243 PETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPP 302 PE P GT L V A D DEG+NGEV YS +L +F ++ +GE++++ +L Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLL-KFQLNKYTGEIKISENLDYE 314 Query: 303 ET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIAL 361 ET E I+A D G + +TAK+L+ V DVND++PEL +L +PV ED+ GTV+AL Sbjct: 315 ETGFYEIEIQAEDGGAY--LATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372 Query: 362 FSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSG 421 +V D D + NG+V C + + PF+L S D+YY L+I LDREQ+S Y + +TA+D G Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432 Query: 422 SPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVS 481 SPPLST + VAD+NDN P F Q ++ ENN GAS+ V A DPD +N + Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492 Query: 482 YELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTI 541 Y L + +G SS +++ S +G + A SFD+EQ QV D G PP S+ V++ Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552 Query: 542 NLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600 +LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612 Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660 +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+ Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672 Query: 661 PQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ 709 PQ+L D P + S LYLV+A+A +S +FL ++ + +L + Sbjct: 673 PQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRR 722 >gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor [Homo sapiens] Length = 837 Score = 595 bits (1534), Expect = e-170 Identities = 328/771 (42%), Positives = 473/771 (61%), Gaps = 24/771 (3%) Query: 8 VLCLWVSC--GAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELY 65 +LC+++ G A Q+ YSVPEETE+G VGN+S DL L ++ R R +S + Sbjct: 16 LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75 Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125 F V+ SG+L+ DRE+LC ++C L +L++ED L+++ + + ++D NDN+P F Sbjct: 76 FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135 Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185 +V++ + E PGARF LPNA+D D G N + SY LSP+ +F L + R DG++ PEL Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195 Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245 VLE +LDRE+ A HLL+LTA DGG P R G + ++V+D ND+ P+F +SVYR VPE Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255 Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPET 304 +GT + V A DPDEG NGEV YS N +++ F + ++GEVQV SL Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRN-MESKASEIFQLDSQTGEVQVRGSLDFEKYR 314 Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364 E I+ +D G GL +T +L+ V DVND+APE+ + N + E++ PGTVIAL +V Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372 Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424 +D+D NG+V C + + PF+L ++ NYY L+ LDRE + Y + +TA+D GSPP Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432 Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484 LS + ++VAD NDN P FP ++ ENN GAS+ V A DPD +N LV+Y L Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492 Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544 D +G SS +++ S++G + A SFD+EQ R +V RD G PP S+ V+++LF Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552 Query: 545 VVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603 V+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +A Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKA 612 Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663 S+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++ Sbjct: 613 SEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEV 672 Query: 664 LPDFEDVWE-PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCC 719 L D + + S +LYLV+A+A +S +FL ++ + +L H+S Sbjct: 673 LADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKS--------- 723 Query: 720 RSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 L S+ TS + V V+ QTY + SL S + L+ Sbjct: 724 ----RLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLI 770 >gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor [Homo sapiens] Length = 935 Score = 595 bits (1534), Expect = e-170 Identities = 328/771 (42%), Positives = 473/771 (61%), Gaps = 24/771 (3%) Query: 8 VLCLWVSC--GAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELY 65 +LC+++ G A Q+ YSVPEETE+G VGN+S DL L ++ R R +S + Sbjct: 16 LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75 Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125 F V+ SG+L+ DRE+LC ++C L +L++ED L+++ + + ++D NDN+P F Sbjct: 76 FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135 Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185 +V++ + E PGARF LPNA+D D G N + SY LSP+ +F L + R DG++ PEL Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195 Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245 VLE +LDRE+ A HLL+LTA DGG P R G + ++V+D ND+ P+F +SVYR VPE Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255 Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPET 304 +GT + V A DPDEG NGEV YS N +++ F + ++GEVQV SL Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRN-MESKASEIFQLDSQTGEVQVRGSLDFEKYR 314 Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364 E I+ +D G GL +T +L+ V DVND+APE+ + N + E++ PGTVIAL +V Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372 Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424 +D+D NG+V C + + PF+L ++ NYY L+ LDRE + Y + +TA+D GSPP Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432 Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484 LS + ++VAD NDN P FP ++ ENN GAS+ V A DPD +N LV+Y L Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492 Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544 D +G SS +++ S++G + A SFD+EQ R +V RD G PP S+ V+++LF Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552 Query: 545 VVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603 V+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +A Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKA 612 Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663 S+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++ Sbjct: 613 SEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEV 672 Query: 664 LPDFEDVWE-PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCC 719 L D + + S +LYLV+A+A +S +FL ++ + +L H+S Sbjct: 673 LADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKS--------- 723 Query: 720 RSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 L S+ TS + V V+ QTY + SL S + L+ Sbjct: 724 ----RLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLI 770 >gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor [Homo sapiens] Length = 1007 Score = 587 bits (1512), Expect = e-167 Identities = 320/779 (41%), Positives = 476/779 (61%), Gaps = 17/779 (2%) Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRF--LSSHRELY 65 +L L + G AA QL YSVPEE G VGN++ L L + R L + Y Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89 Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125 +DL SG L V E DRE LC + C+L+ +++ +P+ + + + +LD NDNSP FP Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149 Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185 + QL + E + PGARF + +AQD D G+N + +Y LSPS+HF LD+ + S+ EL Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209 Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245 VL K LDREQ A H LVLTA DGG+PARSG AQ+++ V+DTNDN+P F++S YR ++ E Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269 Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPE-T 304 +P GT++ ++ A DPDEGSNGE++YSLS+ T R F + +GEV+V L E + Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329 Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364 + Y++A D G +A K+LV++ DVND+APE+ L +PVPE+A P T++A+ SV Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389 Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424 D+D N +V G+ + PF+L F N Y+L++ GPLDRE+++ Y + +TA+D G P Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRLNG-FGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448 Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484 L++ RT+ V ++D+NDN P+F + +++ ENN PG L V A DPD +N V+Y L Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508 Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544 L+ +G +S +++ S+SG++ A SFD+E+ R F VE +D G PP S+TVT N++ Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568 Query: 545 VVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRAS 604 VVD ND+ P IL+P N S E+VPR+A G+LVTKV+A D+DSG NAWL YH+++ S Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628 Query: 605 DSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLL 664 D LF++ + GE+RT R + + VVVRD+G+P LS+SV + V + + V ++L Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688 Query: 665 PDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ----SPGCCAQSCC- 719 PD + + S LYL+IAL+ +SF+FL ++ K ++ CC C Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748 Query: 720 --RSTEDL------RYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 RS +L +++ + I+V L++TY Y+A L GS +++ + Sbjct: 749 RERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807 >gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor [Homo sapiens] Length = 884 Score = 587 bits (1512), Expect = e-167 Identities = 320/779 (41%), Positives = 476/779 (61%), Gaps = 17/779 (2%) Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRF--LSSHRELY 65 +L L + G AA QL YSVPEE G VGN++ L L + R L + Y Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89 Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125 +DL SG L V E DRE LC + C+L+ +++ +P+ + + + +LD NDNSP FP Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149 Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185 + QL + E + PGARF + +AQD D G+N + +Y LSPS+HF LD+ + S+ EL Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209 Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245 VL K LDREQ A H LVLTA DGG+PARSG AQ+++ V+DTNDN+P F++S YR ++ E Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269 Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPE-T 304 +P GT++ ++ A DPDEGSNGE++YSLS+ T R F + +GEV+V L E + Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329 Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364 + Y++A D G +A K+LV++ DVND+APE+ L +PVPE+A P T++A+ SV Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389 Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424 D+D N +V G+ + PF+L F N Y+L++ GPLDRE+++ Y + +TA+D G P Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRLNG-FGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448 Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484 L++ RT+ V ++D+NDN P+F + +++ ENN PG L V A DPD +N V+Y L Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508 Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544 L+ +G +S +++ S+SG++ A SFD+E+ R F VE +D G PP S+TVT N++ Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568 Query: 545 VVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRAS 604 VVD ND+ P IL+P N S E+VPR+A G+LVTKV+A D+DSG NAWL YH+++ S Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628 Query: 605 DSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLL 664 D LF++ + GE+RT R + + VVVRD+G+P LS+SV + V + + V ++L Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688 Query: 665 PDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ----SPGCCAQSCC- 719 PD + + S LYL+IAL+ +SF+FL ++ K ++ CC C Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748 Query: 720 --RSTEDL------RYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 RS +L +++ + I+V L++TY Y+A L GS +++ + Sbjct: 749 RERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807 >gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor [Homo sapiens] Length = 932 Score = 583 bits (1503), Expect = e-166 Identities = 330/786 (41%), Positives = 472/786 (60%), Gaps = 26/786 (3%) Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 +V G+ + LW + Q+ YSVPEE E+G VG++S DL L ++ R R + Sbjct: 13 LVLLGILLGTLWET---GCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPR 69 Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 R F ++ SG+LV DRE+LC C L D+++ED ++++ + + V D NDN Sbjct: 70 GRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDN 129 Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 +P F ++++ I E RF LP+A D D G N + SY LSP+ HF L + + DGS Sbjct: 130 APYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGS 189 Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 +YPELVL++ALDRE++A H LVLTA DGG P R+G A++ ++V+D NDNAP F + YR Sbjct: 190 KYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRA 249 Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 VPE GT L V A DPDEG N EV+YS + F + SG + L Sbjct: 250 SVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELD 308 Query: 301 PPET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359 E+ + ++A D G ++ AK+L+ V DVND+APE+ +L++ VPE++ GT+I Sbjct: 309 HEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLI 366 Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419 AL +V D+D + NG+VIC + PF+L S+ NYYSL+ D LDREQ+ Y + +TA+D Sbjct: 367 ALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATD 426 Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479 G+PPLST I+++VAD NDN P FPQ ++ ENN G SL V A DPD +N Sbjct: 427 RGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQ 486 Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539 ++Y L + +G S SS +++ S +G + A +SFD+EQ R +V RD G PP S+ V Sbjct: 487 ITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNV 546 Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598 +++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY Sbjct: 547 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606 Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658 + +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666 Query: 659 SVPQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCC 714 S+PQ+L D + P + S LYLV+A+A +S +FL ++ + +L H+S Sbjct: 667 SIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQ 726 Query: 715 AQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGE 774 A G + P S + V V+ QTY + SL S S L+ + Sbjct: 727 AS-----------GGGLTGAP--ASHFVGVDGVQAFLQTYSHEVSLTTDS-RKSHLIFPQ 772 Query: 775 YNAADL 780 N AD+ Sbjct: 773 PNYADM 778 >gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor [Homo sapiens] Length = 820 Score = 583 bits (1503), Expect = e-166 Identities = 330/786 (41%), Positives = 472/786 (60%), Gaps = 26/786 (3%) Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 +V G+ + LW + Q+ YSVPEE E+G VG++S DL L ++ R R + Sbjct: 13 LVLLGILLGTLWET---GCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPR 69 Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 R F ++ SG+LV DRE+LC C L D+++ED ++++ + + V D NDN Sbjct: 70 GRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDN 129 Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 +P F ++++ I E RF LP+A D D G N + SY LSP+ HF L + + DGS Sbjct: 130 APYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGS 189 Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 +YPELVL++ALDRE++A H LVLTA DGG P R+G A++ ++V+D NDNAP F + YR Sbjct: 190 KYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRA 249 Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 VPE GT L V A DPDEG N EV+YS + F + SG + L Sbjct: 250 SVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELD 308 Query: 301 PPET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359 E+ + ++A D G ++ AK+L+ V DVND+APE+ +L++ VPE++ GT+I Sbjct: 309 HEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLI 366 Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419 AL +V D+D + NG+VIC + PF+L S+ NYYSL+ D LDREQ+ Y + +TA+D Sbjct: 367 ALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATD 426 Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479 G+PPLST I+++VAD NDN P FPQ ++ ENN G SL V A DPD +N Sbjct: 427 RGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQ 486 Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539 ++Y L + +G S SS +++ S +G + A +SFD+EQ R +V RD G PP S+ V Sbjct: 487 ITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNV 546 Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598 +++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY Sbjct: 547 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606 Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658 + +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666 Query: 659 SVPQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCC 714 S+PQ+L D + P + S LYLV+A+A +S +FL ++ + +L H+S Sbjct: 667 SIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQ 726 Query: 715 AQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGE 774 A G + P S + V V+ QTY + SL S S L+ + Sbjct: 727 AS-----------GGGLTGAP--ASHFVGVDGVQAFLQTYSHEVSLTTDS-RKSHLIFPQ 772 Query: 775 YNAADL 780 N AD+ Sbjct: 773 PNYADM 778 >gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor [Homo sapiens] Length = 871 Score = 579 bits (1492), Expect = e-165 Identities = 318/720 (44%), Positives = 437/720 (60%), Gaps = 16/720 (2%) Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67 +L L+ G GQ+ Y VPEE++ G VGN++ D L ++S+R + + +F Sbjct: 17 LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76 Query: 68 VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127 VDL SG L+++ P DRE LC A+C++ + V E PLE+++ + ++D ND++P FP Sbjct: 77 VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136 Query: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187 + L I E PG RF L AQD D GSN I SY LS ++HF LD+ R DGS PEL+L Sbjct: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196 Query: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247 EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR V E+AP Sbjct: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256 Query: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307 G VL ++ A DPD G +G V + S T +R+ F +HP +G++ + LGP + E Sbjct: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313 Query: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363 Y E ARD G + L V++ DVND+AP + + +PE A PGTV+AL S Sbjct: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373 Query: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423 V+D D SNG V + PF L ++F N +SL+ GPLDRE S Y +++TASD+G+P Sbjct: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433 Query: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483 PLST RTI ++++DVNDN P+F Q E+FV ENN PG L + A DPD G N L+SY Sbjct: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493 Query: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543 LL+ + SASS +++ +GA+ A SFD+EQ + F+V+ RD G PP S+TVT+ L Sbjct: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553 Query: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603 FV+D NDN P +L P R GS+ + +P S GHL+TKV A D DSG NAW+SY + A Sbjct: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613 Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663 D SLF +S GE+RTA + +P D Q++V+VV+D G PPLS+SVTL V L + Sbjct: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672 Query: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLG--------CLLFFVCTKLHQSPGCCA 715 +PD + P S LYL ++L I F+ G CL C G CA Sbjct: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCA 732 >gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor [Homo sapiens] Length = 938 Score = 579 bits (1492), Expect = e-165 Identities = 318/720 (44%), Positives = 437/720 (60%), Gaps = 16/720 (2%) Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67 +L L+ G GQ+ Y VPEE++ G VGN++ D L ++S+R + + +F Sbjct: 17 LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76 Query: 68 VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127 VDL SG L+++ P DRE LC A+C++ + V E PLE+++ + ++D ND++P FP Sbjct: 77 VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136 Query: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187 + L I E PG RF L AQD D GSN I SY LS ++HF LD+ R DGS PEL+L Sbjct: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196 Query: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247 EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR V E+AP Sbjct: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256 Query: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307 G VL ++ A DPD G +G V + S T +R+ F +HP +G++ + LGP + E Sbjct: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313 Query: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363 Y E ARD G + L V++ DVND+AP + + +PE A PGTV+AL S Sbjct: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373 Query: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423 V+D D SNG V + PF L ++F N +SL+ GPLDRE S Y +++TASD+G+P Sbjct: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433 Query: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483 PLST RTI ++++DVNDN P+F Q E+FV ENN PG L + A DPD G N L+SY Sbjct: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493 Query: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543 LL+ + SASS +++ +GA+ A SFD+EQ + F+V+ RD G PP S+TVT+ L Sbjct: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553 Query: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603 FV+D NDN P +L P R GS+ + +P S GHL+TKV A D DSG NAW+SY + A Sbjct: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613 Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663 D SLF +S GE+RTA + +P D Q++V+VV+D G PPLS+SVTL V L + Sbjct: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672 Query: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLG--------CLLFFVCTKLHQSPGCCA 715 +PD + P S LYL ++L I F+ G CL C G CA Sbjct: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCA 732 >gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor [Homo sapiens] Length = 932 Score = 575 bits (1483), Expect = e-164 Identities = 330/777 (42%), Positives = 460/777 (59%), Gaps = 26/777 (3%) Query: 3 GCGVAVLC--LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 G G+A+LC L C +GQ+ YSV EE ++G VGN++ DL L ++ R R +S Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69 Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 R F ++ SG+LV E DRE+LC C++ ++++ED L++ ++ I + D NDN Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129 Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 +P FP ++++ I E PG RF + A D D G N + +Y LSP+ +F L + S +G+ Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189 Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 +YPELVLE+ALDRE++ H LVL A DGG P SG+ + +IV+D NDN P+F + YR Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249 Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 V E P GT L V A DPDEG N +V Y L + ++ FH++ SGEV + SL Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308 Query: 301 PPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359 + + E IEA+D GL S AK+LV V DVND+APE+ +L++ VPE+ G I Sbjct: 309 YEDAMFYEIKIEAQDGP--GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366 Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419 AL V D D NG+V + PF+L S D YY L+ LDREQISEY + + ASD Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426 Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479 GSPPLST IT+ V D+NDN P FP ++ ENN GAS+ V AQDPD N Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486 Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539 ++Y L + +G SS +++ S++G + A SFD+EQ R V D G PP S+ V Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546 Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598 ++NLFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606 Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658 + +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666 Query: 659 SVPQLLPDFEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGC 713 +P +L D + EP + S LYLV+A+A +S +FL ++ + +L H+S Sbjct: 667 RIPDILADLGSL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLL 725 Query: 714 CAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 A G + S P S + V QTY + SL S + L+ Sbjct: 726 QAS-----------GGGLASTP--GSHFVGADGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor [Homo sapiens] Length = 829 Score = 575 bits (1483), Expect = e-164 Identities = 330/777 (42%), Positives = 460/777 (59%), Gaps = 26/777 (3%) Query: 3 GCGVAVLC--LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60 G G+A+LC L C +GQ+ YSV EE ++G VGN++ DL L ++ R R +S Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69 Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120 R F ++ SG+LV E DRE+LC C++ ++++ED L++ ++ I + D NDN Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129 Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180 +P FP ++++ I E PG RF + A D D G N + +Y LSP+ +F L + S +G+ Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189 Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240 +YPELVLE+ALDRE++ H LVL A DGG P SG+ + +IV+D NDN P+F + YR Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249 Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300 V E P GT L V A DPDEG N +V Y L + ++ FH++ SGEV + SL Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308 Query: 301 PPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359 + + E IEA+D GL S AK+LV V DVND+APE+ +L++ VPE+ G I Sbjct: 309 YEDAMFYEIKIEAQDGP--GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366 Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419 AL V D D NG+V + PF+L S D YY L+ LDREQISEY + + ASD Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426 Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479 GSPPLST IT+ V D+NDN P FP ++ ENN GAS+ V AQDPD N Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486 Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539 ++Y L + +G SS +++ S++G + A SFD+EQ R V D G PP S+ V Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546 Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598 ++NLFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606 Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658 + +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666 Query: 659 SVPQLLPDFEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGC 713 +P +L D + EP + S LYLV+A+A +S +FL ++ + +L H+S Sbjct: 667 RIPDILADLGSL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLL 725 Query: 714 CAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 A G + S P S + V QTY + SL S + L+ Sbjct: 726 QAS-----------GGGLASTP--GSHFVGADGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor [Homo sapiens] Length = 820 Score = 574 bits (1480), Expect = e-163 Identities = 326/769 (42%), Positives = 460/769 (59%), Gaps = 24/769 (3%) Query: 9 LCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGV 68 L L V A Q+ YSV EE E G VGN++ DL L ++ R R +S R F + Sbjct: 18 LLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFAL 77 Query: 69 DLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGD 128 + SG LV DRE+LC CV +++LED +++ ++ + ++D NDN P F Sbjct: 78 NPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQ 137 Query: 129 VQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLE 188 ++ + E PGARF LP A D D G N + Y L+ + +F LD+ S DG +YPELVLE Sbjct: 138 REIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLE 197 Query: 189 KALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPN 248 +ALDRE+ A H LVLTA DGG P RSG A++ II+VDTNDNAPVF + Y V E P Sbjct: 198 RALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPV 257 Query: 249 GTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLE 307 GT L V+A DPDEG+NG+V YS + ++ F ++ SG++ + L ++ + Sbjct: 258 GTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYD 316 Query: 308 AYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDE 367 +EA D GL + +K+LV V D ND+APE+ +L++ V E ++PGTVIALF+V D Sbjct: 317 IDVEAHDGP--GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDS 374 Query: 368 DLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLST 427 D NG V C + PF L ++ NYY LL LDRE++SEY + +TA+D G+PPLST Sbjct: 375 DSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLST 434 Query: 428 RRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDV 487 I++ V D+NDN P FP ++ ENN GAS+ + AQDPD G N ++Y L + Sbjct: 435 ETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAED 494 Query: 488 ISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVD 547 +G SS +++ S++G + A SFD+EQ R + D G PP S+ V+++LFV+D Sbjct: 495 TFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLD 554 Query: 548 RNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDS 606 +NDN P IL+P P +GS VE+ PRSA +G+LVTKVVA D DSG NAWLSY + ++S+ Sbjct: 555 QNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEP 614 Query: 607 SLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPD 666 LF + + GE+RTAR +L DA+KQR+VVVV+DHG PPLS++VTL V +++S+P +L D Sbjct: 615 GLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLAD 674 Query: 667 FEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRS 721 + +P S LYLV+A+A +S +FL + + KL H+S A+ Sbjct: 675 LGSL-KPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAE----- 728 Query: 722 TEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 GS++ P S + V V QTY + SL S + L+ Sbjct: 729 ------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor [Homo sapiens] Length = 931 Score = 574 bits (1480), Expect = e-163 Identities = 326/769 (42%), Positives = 460/769 (59%), Gaps = 24/769 (3%) Query: 9 LCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGV 68 L L V A Q+ YSV EE E G VGN++ DL L ++ R R +S R F + Sbjct: 18 LLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFAL 77 Query: 69 DLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGD 128 + SG LV DRE+LC CV +++LED +++ ++ + ++D NDN P F Sbjct: 78 NPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQ 137 Query: 129 VQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLE 188 ++ + E PGARF LP A D D G N + Y L+ + +F LD+ S DG +YPELVLE Sbjct: 138 REIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLE 197 Query: 189 KALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPN 248 +ALDRE+ A H LVLTA DGG P RSG A++ II+VDTNDNAPVF + Y V E P Sbjct: 198 RALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPV 257 Query: 249 GTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLE 307 GT L V+A DPDEG+NG+V YS + ++ F ++ SG++ + L ++ + Sbjct: 258 GTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYD 316 Query: 308 AYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDE 367 +EA D GL + +K+LV V D ND+APE+ +L++ V E ++PGTVIALF+V D Sbjct: 317 IDVEAHDGP--GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDS 374 Query: 368 DLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLST 427 D NG V C + PF L ++ NYY LL LDRE++SEY + +TA+D G+PPLST Sbjct: 375 DSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLST 434 Query: 428 RRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDV 487 I++ V D+NDN P FP ++ ENN GAS+ + AQDPD G N ++Y L + Sbjct: 435 ETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAED 494 Query: 488 ISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVD 547 +G SS +++ S++G + A SFD+EQ R + D G PP S+ V+++LFV+D Sbjct: 495 TFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLD 554 Query: 548 RNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDS 606 +NDN P IL+P P +GS VE+ PRSA +G+LVTKVVA D DSG NAWLSY + ++S+ Sbjct: 555 QNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEP 614 Query: 607 SLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPD 666 LF + + GE+RTAR +L DA+KQR+VVVV+DHG PPLS++VTL V +++S+P +L D Sbjct: 615 GLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLAD 674 Query: 667 FEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRS 721 + +P S LYLV+A+A +S +FL + + KL H+S A+ Sbjct: 675 LGSL-KPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAE----- 728 Query: 722 TEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 GS++ P S + V V QTY + SL S + L+ Sbjct: 729 ------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor [Homo sapiens] Length = 932 Score = 572 bits (1473), Expect = e-163 Identities = 331/771 (42%), Positives = 460/771 (59%), Gaps = 31/771 (4%) Query: 20 GQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVRE 79 GQ+ YSVPEET++G VGN+S DL L ++ R +S R F ++ SG+L+ Sbjct: 29 GQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAG 88 Query: 80 PADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTP 139 DRE+LC C++ + ++ED +L + I ++D NDN+P F D+++ I E P Sbjct: 89 RIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVP 148 Query: 140 GARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATH 199 GAR+ LP A D D G N + SY LSP+ HF LD+ + +G+ PELVLE+ALDRE+ A H Sbjct: 149 GARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208 Query: 200 LLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALD 259 LVLTA DGG P RS ++ + V+DTNDNAPVF +YR KV E P GT L V A D Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLTVTASD 268 Query: 260 PDEGSNGEVQYSLS--NSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEARDEG 316 PDEG NG+V Y N Q L F ++ +GE+ +A SL E + E I+A D G Sbjct: 269 PDEGINGKVAYKFRKINEKQTPL---FQLNENTGEISIAKSLDYEECSFYEMEIQAEDVG 325 Query: 317 VFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVI 376 L KLL+ V DVND+ PE+ +L +PV E++ PGTVIA SV D+D NG+V+ Sbjct: 326 --ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVV 383 Query: 377 CGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVA 436 C PF+L S NYY L+ LDRE +S Y + + ASD G+PPLST I + VA Sbjct: 384 CYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVA 443 Query: 437 DVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASS 496 D+NDN P FP ++ ENN GAS+ + A DPD +N V+Y + + +G SS Sbjct: 444 DINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSS 503 Query: 497 LLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVIL 556 +++ S +G + A SFD+EQ+R V D G PP S+ ++++LFV+D+NDN P IL Sbjct: 504 YISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEIL 563 Query: 557 FP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANI 615 +P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + + Sbjct: 564 YPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHT 623 Query: 616 GELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDV---WE 672 GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L + + + Sbjct: 624 GEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVD 683 Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRSTEDLRYGS 729 P S+ LYLV+A+A IS +FL + + +L H+S R +D G Sbjct: 684 PND--SSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKS---------RLLQD--SGG 730 Query: 730 KMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 ++V P S + V V+ QTY SL S S L+ + N AD+ Sbjct: 731 RLVGVP--ASHFVGVEEVQAFLQTYSQEVSLTADS-RKSHLIFPQPNYADM 778 >gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor [Homo sapiens] Length = 820 Score = 572 bits (1473), Expect = e-163 Identities = 331/771 (42%), Positives = 460/771 (59%), Gaps = 31/771 (4%) Query: 20 GQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVRE 79 GQ+ YSVPEET++G VGN+S DL L ++ R +S R F ++ SG+L+ Sbjct: 29 GQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAG 88 Query: 80 PADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTP 139 DRE+LC C++ + ++ED +L + I ++D NDN+P F D+++ I E P Sbjct: 89 RIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVP 148 Query: 140 GARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATH 199 GAR+ LP A D D G N + SY LSP+ HF LD+ + +G+ PELVLE+ALDRE+ A H Sbjct: 149 GARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208 Query: 200 LLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALD 259 LVLTA DGG P RS ++ + V+DTNDNAPVF +YR KV E P GT L V A D Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLTVTASD 268 Query: 260 PDEGSNGEVQYSLS--NSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEARDEG 316 PDEG NG+V Y N Q L F ++ +GE+ +A SL E + E I+A D G Sbjct: 269 PDEGINGKVAYKFRKINEKQTPL---FQLNENTGEISIAKSLDYEECSFYEMEIQAEDVG 325 Query: 317 VFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVI 376 L KLL+ V DVND+ PE+ +L +PV E++ PGTVIA SV D+D NG+V+ Sbjct: 326 --ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVV 383 Query: 377 CGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVA 436 C PF+L S NYY L+ LDRE +S Y + + ASD G+PPLST I + VA Sbjct: 384 CYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVA 443 Query: 437 DVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASS 496 D+NDN P FP ++ ENN GAS+ + A DPD +N V+Y + + +G SS Sbjct: 444 DINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSS 503 Query: 497 LLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVIL 556 +++ S +G + A SFD+EQ+R V D G PP S+ ++++LFV+D+NDN P IL Sbjct: 504 YISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEIL 563 Query: 557 FP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANI 615 +P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + + Sbjct: 564 YPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHT 623 Query: 616 GELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDV---WE 672 GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L + + + Sbjct: 624 GEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVD 683 Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRSTEDLRYGS 729 P S+ LYLV+A+A IS +FL + + +L H+S R +D G Sbjct: 684 PND--SSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKS---------RLLQD--SGG 730 Query: 730 KMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 ++V P S + V V+ QTY SL S S L+ + N AD+ Sbjct: 731 RLVGVP--ASHFVGVEEVQAFLQTYSQEVSLTADS-RKSHLIFPQPNYADM 778 >gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor [Homo sapiens] Length = 932 Score = 571 bits (1472), Expect = e-163 Identities = 328/759 (43%), Positives = 449/759 (59%), Gaps = 20/759 (2%) Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76 A A Q+ YSVPEETE+G VGN+S DL L ++ R R +S R F ++ SG LV Sbjct: 26 ARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRTQLFSLNPRSGTLV 85 Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136 DRE+LC C++ + +++ED ++L+ I I V D ND++P F A +++ I E Sbjct: 86 TAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEI 145 Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196 PGAR+ LP A D D G N + SY LSP+ HF L++ + +G+ PELVLE+ALDRE+ Sbjct: 146 AVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEA 205 Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256 H LVLTA DGG P RS ++ + V+DTNDNAPVF + +YR KV E P GT L Sbjct: 206 TAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTAT 265 Query: 257 ALDPDEGSNGEVQYSL--SNSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEAR 313 A D DEG NG+V Y N Q+ L F ++ +GE+ A SL E + E I+A Sbjct: 266 ASDLDEGINGKVAYKFWKINEKQSLL---FQLNENTGEISTAKSLDYEECSFYEMEIQAE 322 Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373 D G GL K+L+ V DVND+ PE+ +L +PV EDA GTVI LF+ D D NG Sbjct: 323 DGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDSGKNG 380 Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433 +V+C + F L S ++YY LL LDRE+ SEY + +TA+D G+PPLST IT+ Sbjct: 381 QVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITL 440 Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493 V D+NDN P F Q +++ ENN G S+ V A DPD +N V Y L + +G Sbjct: 441 QVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSP 500 Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553 S+ +++ S +G + A SFD+EQ R QV D G PP S+ V++ LFV+D+NDN P Sbjct: 501 LSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVSLRLFVLDQNDNAP 560 Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612 IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVG 620 Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672 + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P +L D + Sbjct: 621 LHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADSIPDILADLGSLQI 680 Query: 673 PGG-QLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKM 731 P + S LYLV+A+A +S +FL ++ + +L + R+T D G Sbjct: 681 PADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRH---WHSSHLLRATSDGLAG--- 734 Query: 732 VSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 TS + V V QTY SL S + L+ Sbjct: 735 ----VPTSHFVGVDGVRAFLQTYSQEFSLTADSRKSHLI 769 >gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor [Homo sapiens] Length = 828 Score = 571 bits (1472), Expect = e-163 Identities = 328/759 (43%), Positives = 449/759 (59%), Gaps = 20/759 (2%) Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76 A A Q+ YSVPEETE+G VGN+S DL L ++ R R +S R F ++ SG LV Sbjct: 26 ARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRTQLFSLNPRSGTLV 85 Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136 DRE+LC C++ + +++ED ++L+ I I V D ND++P F A +++ I E Sbjct: 86 TAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEI 145 Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196 PGAR+ LP A D D G N + SY LSP+ HF L++ + +G+ PELVLE+ALDRE+ Sbjct: 146 AVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEA 205 Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256 H LVLTA DGG P RS ++ + V+DTNDNAPVF + +YR KV E P GT L Sbjct: 206 TAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTAT 265 Query: 257 ALDPDEGSNGEVQYSL--SNSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEAR 313 A D DEG NG+V Y N Q+ L F ++ +GE+ A SL E + E I+A Sbjct: 266 ASDLDEGINGKVAYKFWKINEKQSLL---FQLNENTGEISTAKSLDYEECSFYEMEIQAE 322 Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373 D G GL K+L+ V DVND+ PE+ +L +PV EDA GTVI LF+ D D NG Sbjct: 323 DGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDSGKNG 380 Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433 +V+C + F L S ++YY LL LDRE+ SEY + +TA+D G+PPLST IT+ Sbjct: 381 QVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITL 440 Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493 V D+NDN P F Q +++ ENN G S+ V A DPD +N V Y L + +G Sbjct: 441 QVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSP 500 Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553 S+ +++ S +G + A SFD+EQ R QV D G PP S+ V++ LFV+D+NDN P Sbjct: 501 LSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVSLRLFVLDQNDNAP 560 Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612 IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVG 620 Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672 + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P +L D + Sbjct: 621 LHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADSIPDILADLGSLQI 680 Query: 673 PGG-QLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKM 731 P + S LYLV+A+A +S +FL ++ + +L + R+T D G Sbjct: 681 PADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRH---WHSSHLLRATSDGLAG--- 734 Query: 732 VSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 TS + V V QTY SL S + L+ Sbjct: 735 ----VPTSHFVGVDGVRAFLQTYSQEFSLTADSRKSHLI 769 >gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor [Homo sapiens] Length = 813 Score = 570 bits (1469), Expect = e-162 Identities = 324/779 (41%), Positives = 456/779 (58%), Gaps = 29/779 (3%) Query: 3 GCGVAVL---CLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLS 59 GCG +L L C +GQ+ YS+PEE ++G VGN++ DL L ++ R R +S Sbjct: 9 GCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVS 68 Query: 60 SHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTND 119 R F ++ SG+LV DRE+LC CV+ +++++E+ ++++ + + ++D ND Sbjct: 69 RGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIND 128 Query: 120 NSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDG 179 N P F ++++ + E G R LP A+D D G N + SY LS + HF LD+ S DG Sbjct: 129 NFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDG 188 Query: 180 SEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYR 239 +YPELVLE+ LDRE+ H L+LTA DGG P SG + + V+D NDNAP+F S Y Sbjct: 189 QKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYS 248 Query: 240 TKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASL 299 VPE P GT L + A DPDEG NG++ YS N + ++ F + GE+ SL Sbjct: 249 VSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEE-KISETFQLDSNLGEISTLQSL 307 Query: 300 GPPET---LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPG 356 E+ L+E + A+D G L ++AK++V V DVND+APE+ +L++ + ED PG Sbjct: 308 DYEESRFYLME--VVAQDGGA--LVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPG 363 Query: 357 TVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLIT 416 TVIALFSV D D NG + C + PF+L S DNYY LL LDRE+ S+Y + +T Sbjct: 364 TVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLT 423 Query: 417 ASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGK 476 D G+PPLST I + VADVNDN PNFPQ V ENN G S+ V A DPD G Sbjct: 424 VMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGD 483 Query: 477 NGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRS 536 N V+Y L + +G SS +++ S +G + A SFD+EQLR V D G PP S Sbjct: 484 NARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLS 543 Query: 537 ATVTINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAW 595 + V+++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAW Sbjct: 544 SNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAW 603 Query: 596 LSYHISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVL 655 LSY + +AS+ LF + + GE+RTAR +L DA+KQ +VV V DHG PPLS++ T+ V Sbjct: 604 LSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVA 663 Query: 656 LSNSVPQLLPDFEDVWEPGGQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKL---HQSP 711 +++ +P +L D + P LYLV+A+A +S +FL ++ + +L H+S Sbjct: 664 VADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSR 723 Query: 712 GCCAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 A+ GS++ P S + V V QTY + SL S + L+ Sbjct: 724 LLQAE-----------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor [Homo sapiens] Length = 931 Score = 570 bits (1469), Expect = e-162 Identities = 324/779 (41%), Positives = 456/779 (58%), Gaps = 29/779 (3%) Query: 3 GCGVAVL---CLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLS 59 GCG +L L C +GQ+ YS+PEE ++G VGN++ DL L ++ R R +S Sbjct: 9 GCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVS 68 Query: 60 SHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTND 119 R F ++ SG+LV DRE+LC CV+ +++++E+ ++++ + + ++D ND Sbjct: 69 RGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIND 128 Query: 120 NSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDG 179 N P F ++++ + E G R LP A+D D G N + SY LS + HF LD+ S DG Sbjct: 129 NFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDG 188 Query: 180 SEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYR 239 +YPELVLE+ LDRE+ H L+LTA DGG P SG + + V+D NDNAP+F S Y Sbjct: 189 QKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYS 248 Query: 240 TKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASL 299 VPE P GT L + A DPDEG NG++ YS N + ++ F + GE+ SL Sbjct: 249 VSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEE-KISETFQLDSNLGEISTLQSL 307 Query: 300 GPPET---LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPG 356 E+ L+E + A+D G L ++AK++V V DVND+APE+ +L++ + ED PG Sbjct: 308 DYEESRFYLME--VVAQDGGA--LVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPG 363 Query: 357 TVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLIT 416 TVIALFSV D D NG + C + PF+L S DNYY LL LDRE+ S+Y + +T Sbjct: 364 TVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLT 423 Query: 417 ASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGK 476 D G+PPLST I + VADVNDN PNFPQ V ENN G S+ V A DPD G Sbjct: 424 VMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGD 483 Query: 477 NGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRS 536 N V+Y L + +G SS +++ S +G + A SFD+EQLR V D G PP S Sbjct: 484 NARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLS 543 Query: 537 ATVTINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAW 595 + V+++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAW Sbjct: 544 SNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAW 603 Query: 596 LSYHISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVL 655 LSY + +AS+ LF + + GE+RTAR +L DA+KQ +VV V DHG PPLS++ T+ V Sbjct: 604 LSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVA 663 Query: 656 LSNSVPQLLPDFEDVWEPGGQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKL---HQSP 711 +++ +P +L D + P LYLV+A+A +S +FL ++ + +L H+S Sbjct: 664 VADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSR 723 Query: 712 GCCAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 A+ GS++ P S + V V QTY + SL S + L+ Sbjct: 724 LLQAE-----------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precursor [Homo sapiens] Length = 808 Score = 567 bits (1462), Expect = e-161 Identities = 309/704 (43%), Positives = 435/704 (61%), Gaps = 11/704 (1%) Query: 22 LEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPA 81 + YS+PEE +G VGNL+ DL L +S+R R S +L+F VD SG+L+V++ Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRV--SAEKLHFSVDAQSGDLLVKDRI 90 Query: 82 DREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGA 141 DREQ+C+ + C L + V+E+PL + + + + D ND++P F ++ L I E ++ G Sbjct: 91 DREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLGM 150 Query: 142 RFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLL 201 L +A+D D N + Y LSP+++F L DG +YPELVL+K LDRE ++ H L Sbjct: 151 GTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHL 210 Query: 202 VLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPD 261 VLTA DGG P RSG AQ+ I+V+D NDN PVF + VYR + E P GT + RV+A D D Sbjct: 211 VLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQD 270 Query: 262 EGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAY---IEARDEGVF 318 EG N E+ YS + +H F + +G + L E +E Y IEA+D G Sbjct: 271 EGINSEITYSFFGVAD-KAQHVFSLDYTTGNILTQQPLDFEE--VERYTINIEAKDRG-- 325 Query: 319 GLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICG 378 L++ K++VEV D ND++PE+ +LS+ + ED+ PG V+ALF +D+D NG V C Sbjct: 326 SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCS 385 Query: 379 MSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADV 438 +S PF++ +S +NYY L+ D LDREQ EY V I A+D G PPLS+ +TIT+ + DV Sbjct: 386 LSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDV 445 Query: 439 NDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLL 498 NDN P F Q + V ENN PGAS+ +V A DPD G NG VSY L+ E + SS + Sbjct: 446 NDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYV 505 Query: 499 AVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFP 558 +V + SG + A+ +FD EQLR F ++ RD G P SA V++ + V DRNDN P +L+P Sbjct: 506 SVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYP 565 Query: 559 -LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGE 617 L +GS + VPR+A+ G+LVTKVVA DADSG NAWLSYH+ +AS+ LF + GE Sbjct: 566 ALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGE 625 Query: 618 LRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPGGQL 677 +R R + D+V+QR++V VRD G PPLS++ TL ++ ++S+ ++LPDF D P Sbjct: 626 VRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQ 685 Query: 678 SAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRS 721 + YLV+ALA IS LFL ++ + +L QS A C S Sbjct: 686 AEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFES 729 >gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor [Homo sapiens] Length = 929 Score = 567 bits (1462), Expect = e-161 Identities = 309/704 (43%), Positives = 435/704 (61%), Gaps = 11/704 (1%) Query: 22 LEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPA 81 + YS+PEE +G VGNL+ DL L +S+R R S +L+F VD SG+L+V++ Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRV--SAEKLHFSVDAQSGDLLVKDRI 90 Query: 82 DREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGA 141 DREQ+C+ + C L + V+E+PL + + + + D ND++P F ++ L I E ++ G Sbjct: 91 DREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLGM 150 Query: 142 RFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLL 201 L +A+D D N + Y LSP+++F L DG +YPELVL+K LDRE ++ H L Sbjct: 151 GTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHL 210 Query: 202 VLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPD 261 VLTA DGG P RSG AQ+ I+V+D NDN PVF + VYR + E P GT + RV+A D D Sbjct: 211 VLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQD 270 Query: 262 EGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAY---IEARDEGVF 318 EG N E+ YS + +H F + +G + L E +E Y IEA+D G Sbjct: 271 EGINSEITYSFFGVAD-KAQHVFSLDYTTGNILTQQPLDFEE--VERYTINIEAKDRG-- 325 Query: 319 GLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICG 378 L++ K++VEV D ND++PE+ +LS+ + ED+ PG V+ALF +D+D NG V C Sbjct: 326 SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCS 385 Query: 379 MSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADV 438 +S PF++ +S +NYY L+ D LDREQ EY V I A+D G PPLS+ +TIT+ + DV Sbjct: 386 LSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDV 445 Query: 439 NDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLL 498 NDN P F Q + V ENN PGAS+ +V A DPD G NG VSY L+ E + SS + Sbjct: 446 NDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYV 505 Query: 499 AVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFP 558 +V + SG + A+ +FD EQLR F ++ RD G P SA V++ + V DRNDN P +L+P Sbjct: 506 SVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYP 565 Query: 559 -LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGE 617 L +GS + VPR+A+ G+LVTKVVA DADSG NAWLSYH+ +AS+ LF + GE Sbjct: 566 ALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGE 625 Query: 618 LRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPGGQL 677 +R R + D+V+QR++V VRD G PPLS++ TL ++ ++S+ ++LPDF D P Sbjct: 626 VRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQ 685 Query: 678 SAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRS 721 + YLV+ALA IS LFL ++ + +L QS A C S Sbjct: 686 AEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFES 729 >gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor [Homo sapiens] Length = 932 Score = 563 bits (1451), Expect = e-160 Identities = 317/757 (41%), Positives = 452/757 (59%), Gaps = 16/757 (2%) Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76 A AG++ YSV EET++G VG+++ DL L ++ R R +S R F ++ SG+LV Sbjct: 26 AWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLV 85 Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136 DRE++C A C++ +++++ED + L+ I + ++D NDN P F ++ + I E Sbjct: 86 TAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMEN 145 Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196 PG RF L A D D G+N + SY LSP++HF L + S D ++YPELVLE+ LDRE+ Sbjct: 146 TAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEE 205 Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256 H LVLTA DGG P RS A + + VVD ND+ PVF Y+ VPE P GT L V Sbjct: 206 RVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVH 265 Query: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLEAYIEARDE 315 A+D DEG NGEV YS T +L FH++ +GE+ L ET E ++A+D Sbjct: 266 AIDLDEGVNGEVTYSFRKIT-PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG 324 Query: 316 GVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRV 375 G + AK+L+ V DVND+APE+ +LS+ +PED GTVIALF ++D D NG V Sbjct: 325 P--GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEV 382 Query: 376 ICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSV 435 C + PF+L S DNYY L+ LDRE +S Y + + A+D G+PPLS I + V Sbjct: 383 TCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQV 442 Query: 436 ADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSAS 495 AD NDN P FP +++AENN GAS+ V AQD D N ++Y L + +G S Sbjct: 443 ADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVS 502 Query: 496 SLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVI 555 S +++ S +G + A SFD+EQLR +V D G PP S+ ++++LFV+D+NDN P I Sbjct: 503 SYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEI 562 Query: 556 LFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISAN 614 L+P LP +GS +E+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + Sbjct: 563 LYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLY 622 Query: 615 IGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPG 674 GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L D + Sbjct: 623 TGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSD 682 Query: 675 GQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMVS 733 G + LYLV+A+A +S +FL +L + +L + + L+ ++ Sbjct: 683 GPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRR---------WHKSRLLQASEGGLA 733 Query: 734 NPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 N TS + + V+ QTY + SL S + L+ Sbjct: 734 N-VPTSHFVGMDGVQAFLQTYSHEVSLTADSRKSHLI 769 >gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor [Homo sapiens] Length = 817 Score = 563 bits (1451), Expect = e-160 Identities = 317/757 (41%), Positives = 452/757 (59%), Gaps = 16/757 (2%) Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76 A AG++ YSV EET++G VG+++ DL L ++ R R +S R F ++ SG+LV Sbjct: 26 AWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLV 85 Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136 DRE++C A C++ +++++ED + L+ I + ++D NDN P F ++ + I E Sbjct: 86 TAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMEN 145 Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196 PG RF L A D D G+N + SY LSP++HF L + S D ++YPELVLE+ LDRE+ Sbjct: 146 TAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEE 205 Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256 H LVLTA DGG P RS A + + VVD ND+ PVF Y+ VPE P GT L V Sbjct: 206 RVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVH 265 Query: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLEAYIEARDE 315 A+D DEG NGEV YS T +L FH++ +GE+ L ET E ++A+D Sbjct: 266 AIDLDEGVNGEVTYSFRKIT-PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG 324 Query: 316 GVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRV 375 G + AK+L+ V DVND+APE+ +LS+ +PED GTVIALF ++D D NG V Sbjct: 325 P--GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEV 382 Query: 376 ICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSV 435 C + PF+L S DNYY L+ LDRE +S Y + + A+D G+PPLS I + V Sbjct: 383 TCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQV 442 Query: 436 ADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSAS 495 AD NDN P FP +++AENN GAS+ V AQD D N ++Y L + +G S Sbjct: 443 ADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVS 502 Query: 496 SLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVI 555 S +++ S +G + A SFD+EQLR +V D G PP S+ ++++LFV+D+NDN P I Sbjct: 503 SYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEI 562 Query: 556 LFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISAN 614 L+P LP +GS +E+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + Sbjct: 563 LYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLY 622 Query: 615 IGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPG 674 GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L D + Sbjct: 623 TGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSD 682 Query: 675 GQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMVS 733 G + LYLV+A+A +S +FL +L + +L + + L+ ++ Sbjct: 683 GPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRR---------WHKSRLLQASEGGLA 733 Query: 734 NPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 N TS + + V+ QTY + SL S + L+ Sbjct: 734 N-VPTSHFVGMDGVQAFLQTYSHEVSLTADSRKSHLI 769 >gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor [Homo sapiens] Length = 810 Score = 563 bits (1450), Expect = e-160 Identities = 304/706 (43%), Positives = 431/706 (61%), Gaps = 9/706 (1%) Query: 15 CGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGN 74 CGA + Q+ Y++PEE G VG L+ DL L + +R R + E YF V L SG+ Sbjct: 24 CGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSA---EDYFNVSLESGD 80 Query: 75 LVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIP 134 L+V DRE++C K C L ++ V E+P+ + + + + D NDN+P F A + L I Sbjct: 81 LLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEIC 140 Query: 135 EFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDRE 194 E PG +F+L +AQD D N + Y+++P+Q+F L DGS+YP L+LEK LDRE Sbjct: 141 ESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDRE 200 Query: 195 QRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFR 254 +++H L+LTA DGG P SG + I V D NDNAPVF + VYR + E P GT + R Sbjct: 201 HQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR 260 Query: 255 VQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAY-IEAR 313 V A D DEG N E+ Y+ NS + F+++P +G++ +L ET +EA+ Sbjct: 261 VMATDQDEGINAEITYAFLNSPIST--SLFNLNPNTGDITTNGTLDFEETSRYVLSVEAK 318 Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373 D GV + + +E+ D ND+APE+ F++ SN +PED+ GTVIAL V+D+D NG Sbjct: 319 DGGVH--TAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQNG 376 Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433 V C PF+L ++ NYY L+I G L+REQ ++Y V I A+D G P LS+R +IT+ Sbjct: 377 MVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSITL 436 Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493 ++D+NDN P F Q + V+ENN PGAS+ +V A DPDLG NG VSY +L E Sbjct: 437 HISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEPRE 496 Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553 S ++V SG + A+ +FD EQLR F ++ RD G P SA V++ + V D NDN P Sbjct: 497 LLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAP 556 Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612 +L+P L +GS ++VPR+A G+LVTKVVA DADSG NAWLSYH+ +AS+ LF + Sbjct: 557 RVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLG 616 Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672 GE+RTAR + DA +QR++V VRD G PPLS++ TL ++ ++S+ ++LPD D E Sbjct: 617 LRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRPE 676 Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSC 718 P + YLV+ALA IS LFL ++ + +L +S + C Sbjct: 677 PSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGC 722 >gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor [Homo sapiens] Length = 927 Score = 563 bits (1450), Expect = e-160 Identities = 304/706 (43%), Positives = 431/706 (61%), Gaps = 9/706 (1%) Query: 15 CGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGN 74 CGA + Q+ Y++PEE G VG L+ DL L + +R R + E YF V L SG+ Sbjct: 24 CGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSA---EDYFNVSLESGD 80 Query: 75 LVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIP 134 L+V DRE++C K C L ++ V E+P+ + + + + D NDN+P F A + L I Sbjct: 81 LLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEIC 140 Query: 135 EFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDRE 194 E PG +F+L +AQD D N + Y+++P+Q+F L DGS+YP L+LEK LDRE Sbjct: 141 ESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDRE 200 Query: 195 QRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFR 254 +++H L+LTA DGG P SG + I V D NDNAPVF + VYR + E P GT + R Sbjct: 201 HQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR 260 Query: 255 VQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAY-IEAR 313 V A D DEG N E+ Y+ NS + F+++P +G++ +L ET +EA+ Sbjct: 261 VMATDQDEGINAEITYAFLNSPIST--SLFNLNPNTGDITTNGTLDFEETSRYVLSVEAK 318 Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373 D GV + + +E+ D ND+APE+ F++ SN +PED+ GTVIAL V+D+D NG Sbjct: 319 DGGVH--TAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQNG 376 Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433 V C PF+L ++ NYY L+I G L+REQ ++Y V I A+D G P LS+R +IT+ Sbjct: 377 MVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSITL 436 Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493 ++D+NDN P F Q + V+ENN PGAS+ +V A DPDLG NG VSY +L E Sbjct: 437 HISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEPRE 496 Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553 S ++V SG + A+ +FD EQLR F ++ RD G P SA V++ + V D NDN P Sbjct: 497 LLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAP 556 Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612 +L+P L +GS ++VPR+A G+LVTKVVA DADSG NAWLSYH+ +AS+ LF + Sbjct: 557 RVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLG 616 Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672 GE+RTAR + DA +QR++V VRD G PPLS++ TL ++ ++S+ ++LPD D E Sbjct: 617 LRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRPE 676 Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSC 718 P + YLV+ALA IS LFL ++ + +L +S + C Sbjct: 677 PSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGC 722 >gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor [Homo sapiens] Length = 932 Score = 562 bits (1448), Expect = e-160 Identities = 320/764 (41%), Positives = 453/764 (59%), Gaps = 21/764 (2%) Query: 11 LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDL 70 LW GAAA Q+ YS+PEE E+G VGN+ DL L ++ R +S R F ++ Sbjct: 23 LW---GAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNP 79 Query: 71 PSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQ 130 +G+LV DRE+LC C++++++++ED L L+ + + ++D NDN+P F +++ Sbjct: 80 RNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELE 139 Query: 131 LHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKA 190 + I E P +RF L D D G N + + LS + HF +D+ S G +YPELVLE Sbjct: 140 VKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGT 199 Query: 191 LDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGT 250 LDRE A + LVLTA DGG P RS AQ+ + V+D NDN P+F + VYR VPE P GT Sbjct: 200 LDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGT 259 Query: 251 VLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPETLLEAY 309 + V A D DEG +GEV YS T+ ++ F ++ +GE+ +A+L + E Sbjct: 260 PVLAVTATDQDEGVHGEVTYSFVKITE-KISQIFCLNVLTGEISTSANLDYEDSSFYELG 318 Query: 310 IEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDL 369 +EARD GL AK+L+ + DVND+ PE+ + S + E A PGTVIALF V D D Sbjct: 319 VEARDGP--GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDS 376 Query: 370 DSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRR 429 NG V C + + PF+L S NYY L+ + LDRE++ Y + +TA+D G+PPLST Sbjct: 377 GLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTET 436 Query: 430 TITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVIS 489 I+++VAD NDN P FP ++V ENN GAS+ V A DPD+ +N VSY L + Sbjct: 437 IISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTL 496 Query: 490 EGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRN 549 +G SS +++ S +G + A SFD+EQLR V D G PP S+ V+++LFV+D+N Sbjct: 497 QGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQN 556 Query: 550 DNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSL 608 DN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ L Sbjct: 557 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 616 Query: 609 FRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFE 668 F + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ +P +L D Sbjct: 617 FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLG 676 Query: 669 DVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLR 726 + EP + S LYLV+A+A +S +FL ++ + +L Q +S Sbjct: 677 SL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRL--------QRWHKSRLLQA 727 Query: 727 YGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 G + S P S + V V QTY + SL S + L+ Sbjct: 728 SGGGLASMP--GSHFVGVEGVRAFLQTYSHEVSLTADSRKSHLI 769 >gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor [Homo sapiens] Length = 818 Score = 562 bits (1448), Expect = e-160 Identities = 320/764 (41%), Positives = 453/764 (59%), Gaps = 21/764 (2%) Query: 11 LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDL 70 LW GAAA Q+ YS+PEE E+G VGN+ DL L ++ R +S R F ++ Sbjct: 23 LW---GAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNP 79 Query: 71 PSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQ 130 +G+LV DRE+LC C++++++++ED L L+ + + ++D NDN+P F +++ Sbjct: 80 RNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELE 139 Query: 131 LHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKA 190 + I E P +RF L D D G N + + LS + HF +D+ S G +YPELVLE Sbjct: 140 VKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGT 199 Query: 191 LDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGT 250 LDRE A + LVLTA DGG P RS AQ+ + V+D NDN P+F + VYR VPE P GT Sbjct: 200 LDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGT 259 Query: 251 VLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPETLLEAY 309 + V A D DEG +GEV YS T+ ++ F ++ +GE+ +A+L + E Sbjct: 260 PVLAVTATDQDEGVHGEVTYSFVKITE-KISQIFCLNVLTGEISTSANLDYEDSSFYELG 318 Query: 310 IEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDL 369 +EARD GL AK+L+ + DVND+ PE+ + S + E A PGTVIALF V D D Sbjct: 319 VEARDGP--GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDS 376 Query: 370 DSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRR 429 NG V C + + PF+L S NYY L+ + LDRE++ Y + +TA+D G+PPLST Sbjct: 377 GLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTET 436 Query: 430 TITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVIS 489 I+++VAD NDN P FP ++V ENN GAS+ V A DPD+ +N VSY L + Sbjct: 437 IISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTL 496 Query: 490 EGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRN 549 +G SS +++ S +G + A SFD+EQLR V D G PP S+ V+++LFV+D+N Sbjct: 497 QGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQN 556 Query: 550 DNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSL 608 DN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ L Sbjct: 557 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 616 Query: 609 FRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFE 668 F + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ +P +L D Sbjct: 617 FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLG 676 Query: 669 DVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLR 726 + EP + S LYLV+A+A +S +FL ++ + +L Q +S Sbjct: 677 SL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRL--------QRWHKSRLLQA 727 Query: 727 YGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770 G + S P S + V V QTY + SL S + L+ Sbjct: 728 SGGGLASMP--GSHFVGVEGVRAFLQTYSHEVSLTADSRKSHLI 769 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,142,844 Number of Sequences: 37866 Number of extensions: 1510585 Number of successful extensions: 10003 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 185 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 3519 Number of HSP's gapped (non-prelim): 573 length of query: 818 length of database: 18,247,518 effective HSP length: 111 effective length of query: 707 effective length of database: 14,044,392 effective search space: 9929385144 effective search space used: 9929385144 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.