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Search of human proteins with 14717401
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14717401 protocadherin alpha subfamily C, 1 isoform 1
precursor [Homo sapiens]
(963 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precurs... 1920 0.0
gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precurs... 1605 0.0
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 890 0.0
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 818 0.0
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 622 e-178
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 617 e-176
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 608 e-173
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 605 e-173
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 602 e-172
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 599 e-171
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 598 e-171
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 596 e-170
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 595 e-170
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 595 e-170
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 590 e-168
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 590 e-168
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 588 e-167
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 587 e-167
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 583 e-166
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 583 e-166
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs... 581 e-165
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 581 e-165
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 580 e-165
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 579 e-165
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 577 e-164
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs... 575 e-164
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 574 e-163
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso... 572 e-163
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs... 571 e-162
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 570 e-162
>gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precursor
[Homo sapiens]
Length = 963
Score = 1920 bits (4973), Expect = 0.0
Identities = 963/963 (100%), Positives = 963/963 (100%)
Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS
Sbjct: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN
Sbjct: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS
Sbjct: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT
Sbjct: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG
Sbjct: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
Query: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360
PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA
Sbjct: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360
Query: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420
LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS
Sbjct: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420
Query: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480
GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV
Sbjct: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480
Query: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540
SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT
Sbjct: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540
Query: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600
INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI
Sbjct: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600
Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660
SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV
Sbjct: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660
Query: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720
PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR
Sbjct: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720
Query: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780
STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL
Sbjct: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780
Query: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI 840
RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI
Sbjct: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI 840
Query: 841 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK 900
LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK
Sbjct: 841 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK 900
Query: 901 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN 960
FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN
Sbjct: 901 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN 960
Query: 961 SDQ 963
SDQ
Sbjct: 961 SDQ 963
>gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 1605 bits (4157), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS
Sbjct: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN
Sbjct: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS
Sbjct: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT
Sbjct: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG
Sbjct: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
Query: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360
PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA
Sbjct: 301 PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA 360
Query: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420
LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS
Sbjct: 361 LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS 420
Query: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480
GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV
Sbjct: 421 GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV 480
Query: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540
SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT
Sbjct: 481 SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT 540
Query: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600
INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI
Sbjct: 541 INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600
Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660
SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV
Sbjct: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660
Query: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720
PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR
Sbjct: 661 PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720
Query: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780
STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL
Sbjct: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780
Query: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAM 811
RNLATGVGLNLPISCIQIRNRKGDHANVNAM
Sbjct: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAM 811
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 890 bits (2300), Expect = 0.0
Identities = 481/984 (48%), Positives = 641/984 (65%), Gaps = 34/984 (3%)
Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRF--LSSHRELY 65
+L L + G AA QL YSVPEE G VGN++ L L + R L + Y
Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125
+DL SG L V E DRE LC + C+L+ +++ +P+ + + + +LD NDNSP FP
Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185
+ QL + E + PGARF + +AQD D G+N + +Y LSPS+HF LD+ + S+ EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245
VL K LDREQ A H LVLTA DGG+PARSG AQ+++ V+DTNDN+P F++S YR ++ E
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPE-T 304
+P GT++ ++ A DPDEGSNGE++YSLS+ T R F + +GEV+V L E +
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364
+ Y++A D G +A K+LV++ DVND+APE+ L +PVPE+A P T++A+ SV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424
D+D N +V G+ + PF+L F N Y+L++ GPLDRE+++ Y + +TA+D G P
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRLNG-FGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484
L++ RT+ V ++D+NDN P+F + +++ ENN PG L V A DPD +N V+Y L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544
L+ +G +S +++ S+SG++ A SFD+E+ R F VE +D G PP S+TVT N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
Query: 545 VVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRAS 604
VVD ND+ P IL+P N S E+VPR+A G+LVTKV+A D+DSG NAWL YH+++ S
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
Query: 605 DSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLL 664
D LF++ + GE+RT R + + VVVRD+G+P LS+SV + V + + V ++L
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
Query: 665 PDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ----SPGCCAQSCC- 719
PD + + S LYL+IAL+ +SF+FL ++ K ++ CC C
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748
Query: 720 --RSTEDL------RYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLL 771
RS +L +++ + I+V L++TY Y+A L GS +++ +
Sbjct: 749 RERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFMF 808
Query: 772 RG------------EYNAADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDW 819
+ D RNL G N + I ++N A PRQPNPDW
Sbjct: 809 YNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAG-NLIILKNE----AVSQNEPRQPNPDW 863
Query: 820 RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNS 879
RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNS
Sbjct: 864 RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNS 923
Query: 880 WTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKK 939
WTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKK
Sbjct: 924 WTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKK 983
Query: 940 KKKKGNKTQEKKEKGNSTTDNSDQ 963
KKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 984 KKKKGNKTQEKKEKGNSTTDNSDQ 1007
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 818 bits (2112), Expect = 0.0
Identities = 455/963 (47%), Positives = 590/963 (61%), Gaps = 36/963 (3%)
Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67
+L L + +GQL YSVPEE + G VG ++ DL L A + R FR S
Sbjct: 17 LLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHRDLLE 76
Query: 68 VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127
V L +G L V DRE+LC A C + +++++ PL++ + + V D NDN P+F
Sbjct: 77 VSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVK 136
Query: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187
D +L + E P +RF L A D D G+N +L+Y LS +F LD+ S+ D ++ ELVL
Sbjct: 137 DQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKLVELVL 196
Query: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247
K+LDRE H L LTA DGG P +G Q+ + V+D NDNAP FE+S Y ++ E A
Sbjct: 197 RKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENAD 256
Query: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPETLL 306
NGT + ++ A DPDEG+NG + YS ++ + + F + +GE+ + +L E L
Sbjct: 257 NGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 307 EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKD 366
+ I+A D+G +A +LV + D ND+ PE+ +LS PV EDA GTVIAL SV D
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVND 376
Query: 367 EDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLS 426
D +NG+V C + PF+L ++F NYYSL++D LDRE++S Y++++TA D GSP L
Sbjct: 377 LDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLW 436
Query: 427 TRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLD 486
+++V VADVNDN P F QP+ +FV ENN PG + V A+D D +N LVSY L++
Sbjct: 437 ATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVE 496
Query: 487 VISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVV 546
S SS ++V + SG + A D E+L FQV RD G+PP + VT+ +FV+
Sbjct: 497 RRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVL 556
Query: 547 DRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASD 605
D NDN P +L P + G ++VPRS GH+V KV A DADSG NAWLSY + A+
Sbjct: 557 DENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAS 616
Query: 606 SSL--FRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLL--SNSVP 661
S FR+ GE+ T R++ D+ + R++V+V+DHG+P L+++ T+ V L S P
Sbjct: 617 SPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAP 676
Query: 662 QLLP-DFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720
+ V P L N+YL+IA+ +S L + LL + + P + CR
Sbjct: 677 KASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP---TEGGCR 733
Query: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780
+ + S V + SQ R G G L+ DL
Sbjct: 734 AGKPTLVCSSAVGS-------------WSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
Query: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI 840
++ G +L + DH PRQPNPDWRYSASLRAGMHSSVHLEEAGI
Sbjct: 781 GSVDVGEEQDLNV----------DHG---LKPRQPNPDWRYSASLRAGMHSSVHLEEAGI 827
Query: 841 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK 900
LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK
Sbjct: 828 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK 887
Query: 901 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN 960
FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN
Sbjct: 888 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN 947
Query: 961 SDQ 963
SDQ
Sbjct: 948 SDQ 950
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 622 bits (1605), Expect = e-178
Identities = 385/953 (40%), Positives = 546/953 (57%), Gaps = 48/953 (5%)
Query: 5 GVAVLCLW--VSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHR 62
G+ +LCL+ + A A Q+ YS+PEE E+G VGN+S DL L ++ R R +S R
Sbjct: 16 GLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75
Query: 63 ELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSP 122
F ++ SG+L+ DRE+LC A CV+++++++ED ++L I I V D NDN+P
Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135
Query: 123 LFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEY 182
F A ++ + I E + G RF LP A D D G N + SY LSP++HF L + SR +G +Y
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195
Query: 183 PELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKV 242
PELVLE +LDRE+ A H LVLTA DGG P RSG V++ V D NDNAPVF YR V
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255
Query: 243 PETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPP 302
PE P GT L V A D DEG+NGEV YS +L +F ++ +GE++++ +L
Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLL-KFQLNKYTGEIKISENLDYE 314
Query: 303 ET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIAL 361
ET E I+A D G + +TAK+L+ V DVND++PEL +L +PV ED+ GTV+AL
Sbjct: 315 ETGFYEIEIQAEDGGAY--LATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372
Query: 362 FSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSG 421
+V D D + NG+V C + + PF+L S D+YY L+I LDREQ+S Y + +TA+D G
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432
Query: 422 SPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVS 481
SPPLST + VAD+NDN P F Q ++ ENN GAS+ V A DPD +N +
Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492
Query: 482 YELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTI 541
Y L + +G SS +++ S +G + A SFD+EQ QV D G PP S+ V++
Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552
Query: 542 NLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600
+LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY +
Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612
Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660
+AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+
Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672
Query: 661 PQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQ 716
PQ+L D P + S LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 673 PQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKS------ 726
Query: 717 SCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYN 776
R + G VS S + V V QTY + SL S S L+ + N
Sbjct: 727 ---RLLQASGGGLTGVSG----SHFVGVDGVRAFLQTYSHEVSLTADS-RKSHLIFPQPN 778
Query: 777 AADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPR-QPNPDWRYSASLRAGMHSSVHL 835
AD N P+S + + K + +P+ PN DWR+S + R G S +
Sbjct: 779 YADTLISQESCEKNDPLSLLD--DSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNG 836
Query: 836 EEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGN 888
++ G P+ Q+ T ++SA+ EA + S +G G + + +YGP
Sbjct: 837 DDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQF 887
Query: 889 PKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 888 TLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 936
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 617 bits (1592), Expect = e-176
Identities = 372/952 (39%), Positives = 546/952 (57%), Gaps = 50/952 (5%)
Query: 8 VLCLWVSC--GAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELY 65
+LC+++ G A Q+ YSVPEETE+G VGN+S DL L ++ R R +S +
Sbjct: 16 LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75
Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125
F V+ SG+L+ DRE+LC ++C L +L++ED L+++ + + ++D NDN+P F
Sbjct: 76 FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135
Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185
+V++ + E PGARF LPNA+D D G N + SY LSP+ +F L + R DG++ PEL
Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195
Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245
VLE +LDRE+ A HLL+LTA DGG P R G + ++V+D ND+ P+F +SVYR VPE
Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255
Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPET 304
+GT + V A DPDEG NGEV YS N +++ F + ++GEVQV SL
Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRN-MESKASEIFQLDSQTGEVQVRGSLDFEKYR 314
Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364
E I+ +D G GL +T +L+ V DVND+APE+ + N + E++ PGTVIAL +V
Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372
Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424
+D+D NG+V C + + PF+L ++ NYY L+ LDRE + Y + +TA+D GSPP
Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432
Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484
LS + ++VAD NDN P FP ++ ENN GAS+ V A DPD +N LV+Y L
Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492
Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544
D +G SS +++ S++G + A SFD+EQ R +V RD G PP S+ V+++LF
Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552
Query: 545 VVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603
V+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +A
Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKA 612
Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663
S+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++
Sbjct: 613 SEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEV 672
Query: 664 LPDFEDVWE-PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCC 719
L D + + S +LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 673 LADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKS--------- 723
Query: 720 RSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAAD 779
L S+ TS + V V+ QTY + SL + S L+ + N D
Sbjct: 724 ----RLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSL-IADSQKSHLIFPQPNYGD 778
Query: 780 LRNLATGVGLNLPISCIQ---IRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLE 836
+ P+ + I K D + P PN DWR+S + R G S + +
Sbjct: 779 TLISQESCEKSEPLLIAEDSAIILGKCDPTSNQQAP--PNTDWRFSQAQRPGTSGSQNGD 836
Query: 837 EAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNP 889
+ G P+ Q+ T ++SA+ EA + S +G G + + +YGP
Sbjct: 837 DTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFT 887
Query: 890 KQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 888 LQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 935
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 608 bits (1567), Expect = e-173
Identities = 371/955 (38%), Positives = 540/955 (56%), Gaps = 49/955 (5%)
Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
+V G+ + LW + Q+ YSVPEE E+G VG++S DL L ++ R R +
Sbjct: 13 LVLLGILLGTLWET---GCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPR 69
Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
R F ++ SG+LV DRE+LC C L D+++ED ++++ + + V D NDN
Sbjct: 70 GRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDN 129
Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
+P F ++++ I E RF LP+A D D G N + SY LSP+ HF L + + DGS
Sbjct: 130 APYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGS 189
Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
+YPELVL++ALDRE++A H LVLTA DGG P R+G A++ ++V+D NDNAP F + YR
Sbjct: 190 KYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRA 249
Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
VPE GT L V A DPDEG N EV+YS + F + SG + L
Sbjct: 250 SVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELD 308
Query: 301 PPET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359
E+ + ++A D G ++ AK+L+ V DVND+APE+ +L++ VPE++ GT+I
Sbjct: 309 HEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLI 366
Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419
AL +V D+D + NG+VIC + PF+L S+ NYYSL+ D LDREQ+ Y + +TA+D
Sbjct: 367 ALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATD 426
Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479
G+PPLST I+++VAD NDN P FPQ ++ ENN G SL V A DPD +N
Sbjct: 427 RGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQ 486
Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539
++Y L + +G S SS +++ S +G + A +SFD+EQ R +V RD G PP S+ V
Sbjct: 487 ITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNV 546
Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598
+++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY
Sbjct: 547 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658
+ +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 659 SVPQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCC 714
S+PQ+L D + P + S LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 667 SIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQ 726
Query: 715 AQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGE 774
A G + P S + V V+ QTY + SL S S L+ +
Sbjct: 727 AS-----------GGGLTGAP--ASHFVGVDGVQAFLQTYSHEVSLTTDS-RKSHLIFPQ 772
Query: 775 YNAADLRNLATGVGLNLPISCI-QIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSV 833
N AD+ + P+ K H + P PN DWR+S + R G S
Sbjct: 773 PNYADMLVSQESFEKSEPLLLSGDSVFSKDSHGLIEQAP--PNTDWRFSQAQRPGTSGSQ 830
Query: 834 HLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGP 886
+ ++ G P+ Q+ T ++SA+ EA + S +G G + + +YGP
Sbjct: 831 NGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGP 881
Query: 887 GNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 882 QFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 605 bits (1559), Expect = e-173
Identities = 377/956 (39%), Positives = 535/956 (55%), Gaps = 50/956 (5%)
Query: 3 GCGVAVLC--LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
G G+A+LC L C +GQ+ YSV EE ++G VGN++ DL L ++ R R +S
Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69
Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
R F ++ SG+LV E DRE+LC C++ ++++ED L++ ++ I + D NDN
Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129
Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
+P FP ++++ I E PG RF + A D D G N + +Y LSP+ +F L + S +G+
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189
Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
+YPELVLE+ALDRE++ H LVL A DGG P SG+ + +IV+D NDN P+F + YR
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249
Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
V E P GT L V A DPDEG N +V Y L + ++ FH++ SGEV + SL
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308
Query: 301 PPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359
+ + E IEA+D GL S AK+LV V DVND+APE+ +L++ VPE+ G I
Sbjct: 309 YEDAMFYEIKIEAQDGP--GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366
Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419
AL V D D NG+V + PF+L S D YY L+ LDREQISEY + + ASD
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426
Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479
GSPPLST IT+ V D+NDN P FP ++ ENN GAS+ V AQDPD N
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486
Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539
++Y L + +G SS +++ S++G + A SFD+EQ R V D G PP S+ V
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598
++NLFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658
+ +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 659 SVPQLLPDFEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGC 713
+P +L D + EP + S LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 667 RIPDILADLGSL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLL 725
Query: 714 CAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRG 773
A G + S P S + V QTY + SL S S L+
Sbjct: 726 QAS-----------GGGLASTP--GSHFVGADGVRAFLQTYSHEVSLTADS-RKSHLIFP 771
Query: 774 EYNAADLRNLATGVGLNLPISCIQ-IRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSS 832
+ N AD + P+ Q + KGD + P PN DWR+S + R G S
Sbjct: 772 QPNYADTLISQESCEKSEPLLITQDLLEMKGDSNLLQQAP--PNTDWRFSQAQRPGTSGS 829
Query: 833 VHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYG 885
+ ++ G P+ Q+ T ++SA+ EA + S +G G + + +YG
Sbjct: 830 QNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYG 880
Query: 886 PGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
P Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 881 PQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 602 bits (1552), Expect = e-172
Identities = 372/948 (39%), Positives = 534/948 (56%), Gaps = 49/948 (5%)
Query: 9 LCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGV 68
L L V A Q+ YSV EE E G VGN++ DL L ++ R R +S R F +
Sbjct: 18 LLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFAL 77
Query: 69 DLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGD 128
+ SG LV DRE+LC CV +++LED +++ ++ + ++D NDN P F
Sbjct: 78 NPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQ 137
Query: 129 VQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLE 188
++ + E PGARF LP A D D G N + Y L+ + +F LD+ S DG +YPELVLE
Sbjct: 138 REIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLE 197
Query: 189 KALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPN 248
+ALDRE+ A H LVLTA DGG P RSG A++ II+VDTNDNAPVF + Y V E P
Sbjct: 198 RALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPV 257
Query: 249 GTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLE 307
GT L V+A DPDEG+NG+V YS + ++ F ++ SG++ + L ++ +
Sbjct: 258 GTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYD 316
Query: 308 AYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDE 367
+EA D GL + +K+LV V D ND+APE+ +L++ V E ++PGTVIALF+V D
Sbjct: 317 IDVEAHDGP--GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDS 374
Query: 368 DLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLST 427
D NG V C + PF L ++ NYY LL LDRE++SEY + +TA+D G+PPLST
Sbjct: 375 DSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLST 434
Query: 428 RRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDV 487
I++ V D+NDN P FP ++ ENN GAS+ + AQDPD G N ++Y L +
Sbjct: 435 ETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAED 494
Query: 488 ISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVD 547
+G SS +++ S++G + A SFD+EQ R + D G PP S+ V+++LFV+D
Sbjct: 495 TFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLD 554
Query: 548 RNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDS 606
+NDN P IL+P P +GS VE+ PRSA +G+LVTKVVA D DSG NAWLSY + ++S+
Sbjct: 555 QNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEP 614
Query: 607 SLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPD 666
LF + + GE+RTAR +L DA+KQR+VVVV+DHG PPLS++VTL V +++S+P +L D
Sbjct: 615 GLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLAD 674
Query: 667 FEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRS 721
+ +P S LYLV+A+A +S +FL + + KL H+S A+
Sbjct: 675 LGSL-KPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAE----- 728
Query: 722 TEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLR 781
GS++ P S + V V QTY + SL S S L+ + + AD
Sbjct: 729 ------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADS-RKSHLIFSQPSYADTL 779
Query: 782 NLATGVGLNLPISCIQ-IRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI 840
+ P+ Q + KGD N PN DWR+S + R G S + ++ G
Sbjct: 780 ISRESCEKSEPLLITQDLLETKGD---PNLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT 836
Query: 841 LRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSG 893
P+ Q+ T ++SA+ EA + S +G G + + +YGP Q
Sbjct: 837 ------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHV 887
Query: 894 PGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 888 P-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 931
>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 599 bits (1545), Expect = e-171
Identities = 372/937 (39%), Positives = 522/937 (55%), Gaps = 42/937 (4%)
Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76
A A Q+ YSVPEETE+G VGN+S DL L ++ R R +S R F ++ SG LV
Sbjct: 26 ARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRTQLFSLNPRSGTLV 85
Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136
DRE+LC C++ + +++ED ++L+ I I V D ND++P F A +++ I E
Sbjct: 86 TAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEI 145
Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196
PGAR+ LP A D D G N + SY LSP+ HF L++ + +G+ PELVLE+ALDRE+
Sbjct: 146 AVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEA 205
Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256
H LVLTA DGG P RS ++ + V+DTNDNAPVF + +YR KV E P GT L
Sbjct: 206 TAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTAT 265
Query: 257 ALDPDEGSNGEVQYSL--SNSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEAR 313
A D DEG NG+V Y N Q+ L F ++ +GE+ A SL E + E I+A
Sbjct: 266 ASDLDEGINGKVAYKFWKINEKQSLL---FQLNENTGEISTAKSLDYEECSFYEMEIQAE 322
Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373
D G GL K+L+ V DVND+ PE+ +L +PV EDA GTVI LF+ D D NG
Sbjct: 323 DGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDSGKNG 380
Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433
+V+C + F L S ++YY LL LDRE+ SEY + +TA+D G+PPLST IT+
Sbjct: 381 QVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITL 440
Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493
V D+NDN P F Q +++ ENN G S+ V A DPD +N V Y L + +G
Sbjct: 441 QVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSP 500
Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553
S+ +++ S +G + A SFD+EQ R QV D G PP S+ V++ LFV+D+NDN P
Sbjct: 501 LSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVSLRLFVLDQNDNAP 560
Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612
IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF +
Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVG 620
Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672
+ GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P +L D +
Sbjct: 621 LHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADSIPDILADLGSLQI 680
Query: 673 PGG-QLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKM 731
P + S LYLV+A+A +S +FL ++ + +L + R+T D G
Sbjct: 681 PADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRH---WHSSHLLRATSDGLAG--- 734
Query: 732 VSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLRNLATGVGLNL 791
TS + V V QTY SL S S L+ + N AD N
Sbjct: 735 ----VPTSHFVGVDGVRAFLQTYSQEFSLTADS-RKSHLIFPQPNYADTLISQQSCEKNE 789
Query: 792 PISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQ 851
P+ C+ + ++ PN DWR+S + R G S + ++ G P+ Q
Sbjct: 790 PL-CVSVDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQ 842
Query: 852 WPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIP 904
+ T ++SA+ EA + S +G G + + +YGP Q P + IP
Sbjct: 843 FDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIP 898
Query: 905 GSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
GS A ++ + K+ G K+++ KK+KK
Sbjct: 899 GSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 598 bits (1543), Expect = e-171
Identities = 372/940 (39%), Positives = 530/940 (56%), Gaps = 54/940 (5%)
Query: 20 GQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVRE 79
GQ+ YSVPEET++G VGN+S DL L ++ R +S R F ++ SG+L+
Sbjct: 29 GQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAG 88
Query: 80 PADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTP 139
DRE+LC C++ + ++ED +L + I ++D NDN+P F D+++ I E P
Sbjct: 89 RIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVP 148
Query: 140 GARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATH 199
GAR+ LP A D D G N + SY LSP+ HF LD+ + +G+ PELVLE+ALDRE+ A H
Sbjct: 149 GARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208
Query: 200 LLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALD 259
LVLTA DGG P RS ++ + V+DTNDNAPVF +YR KV E P GT L V A D
Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLTVTASD 268
Query: 260 PDEGSNGEVQYSLS--NSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEARDEG 316
PDEG NG+V Y N Q L F ++ +GE+ +A SL E + E I+A D G
Sbjct: 269 PDEGINGKVAYKFRKINEKQTPL---FQLNENTGEISIAKSLDYEECSFYEMEIQAEDVG 325
Query: 317 VFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVI 376
L KLL+ V DVND+ PE+ +L +PV E++ PGTVIA SV D+D NG+V+
Sbjct: 326 --ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVV 383
Query: 377 CGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVA 436
C PF+L S NYY L+ LDRE +S Y + + ASD G+PPLST I + VA
Sbjct: 384 CYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVA 443
Query: 437 DVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASS 496
D+NDN P FP ++ ENN GAS+ + A DPD +N V+Y + + +G SS
Sbjct: 444 DINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSS 503
Query: 497 LLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVIL 556
+++ S +G + A SFD+EQ+R V D G PP S+ ++++LFV+D+NDN P IL
Sbjct: 504 YISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEIL 563
Query: 557 FP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANI 615
+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + +
Sbjct: 564 YPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHT 623
Query: 616 GELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDV---WE 672
GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L + + +
Sbjct: 624 GEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVD 683
Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRSTEDLRYGS 729
P S+ LYLV+A+A IS +FL + + +L H+S R +D G
Sbjct: 684 PND--SSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKS---------RLLQD--SGG 730
Query: 730 KMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLRNLATGVGL 789
++V P S + V V+ QTY SL S S L+ + N AD+ G
Sbjct: 731 RLVGVP--ASHFVGVEEVQAFLQTYSQEVSLTADS-RKSHLIFPQPNYADMLISQEGCEK 787
Query: 790 N-LPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP 848
N ++ + K + + P PN DWR+S + R G S + ++ G P
Sbjct: 788 NDSLLTSVDFHEYKNEADHGQQAP--PNTDWRFSQAQRPGTSGSQNGDDTGT------WP 839
Query: 849 DQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKF 901
+ Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 840 NNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNV 895
Query: 902 IIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 896 YIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 596 bits (1537), Expect = e-170
Identities = 368/957 (38%), Positives = 528/957 (55%), Gaps = 52/957 (5%)
Query: 3 GCGVAVL---CLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLS 59
GCG +L L C +GQ+ YS+PEE ++G VGN++ DL L ++ R R +S
Sbjct: 9 GCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVS 68
Query: 60 SHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTND 119
R F ++ SG+LV DRE+LC CV+ +++++E+ ++++ + + ++D ND
Sbjct: 69 RGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIND 128
Query: 120 NSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDG 179
N P F ++++ + E G R LP A+D D G N + SY LS + HF LD+ S DG
Sbjct: 129 NFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDG 188
Query: 180 SEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYR 239
+YPELVLE+ LDRE+ H L+LTA DGG P SG + + V+D NDNAP+F S Y
Sbjct: 189 QKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYS 248
Query: 240 TKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASL 299
VPE P GT L + A DPDEG NG++ YS N + ++ F + GE+ SL
Sbjct: 249 VSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEE-KISETFQLDSNLGEISTLQSL 307
Query: 300 GPPET---LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPG 356
E+ L+E + A+D G L ++AK++V V DVND+APE+ +L++ + ED PG
Sbjct: 308 DYEESRFYLME--VVAQDGGA--LVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPG 363
Query: 357 TVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLIT 416
TVIALFSV D D NG + C + PF+L S DNYY LL LDRE+ S+Y + +T
Sbjct: 364 TVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLT 423
Query: 417 ASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGK 476
D G+PPLST I + VADVNDN PNFPQ V ENN G S+ V A DPD G
Sbjct: 424 VMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGD 483
Query: 477 NGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRS 536
N V+Y L + +G SS +++ S +G + A SFD+EQLR V D G PP S
Sbjct: 484 NARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLS 543
Query: 537 ATVTINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAW 595
+ V+++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAW
Sbjct: 544 SNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAW 603
Query: 596 LSYHISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVL 655
LSY + +AS+ LF + + GE+RTAR +L DA+KQ +VV V DHG PPLS++ T+ V
Sbjct: 604 LSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVA 663
Query: 656 LSNSVPQLLPDFEDVWEPGGQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKL---HQSP 711
+++ +P +L D + P LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 664 VADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSR 723
Query: 712 GCCAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLL 771
A+ GS++ P S + V V QTY + SL S S L+
Sbjct: 724 LLQAE-----------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADS-RKSHLI 769
Query: 772 RGEYNAADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHS 831
+ N AD + P+ + + V P PN DWR+S + R G
Sbjct: 770 FPQPNYADTLLSEESCEKSEPLLMSDKVDANKEERRVQQAP--PNTDWRFSQAQRPGTSG 827
Query: 832 SVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKY 884
S + ++ G P+ Q+ T ++SA+ EA + S +G G + + +Y
Sbjct: 828 SQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARY 878
Query: 885 GPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
GP Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 879 GPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 931
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 595 bits (1535), Expect = e-170
Identities = 323/710 (45%), Positives = 449/710 (63%), Gaps = 8/710 (1%)
Query: 5 GVAVLCLW--VSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHR 62
G+ +LCL+ + A A Q+ YS+PEE E+G VGN+S DL L ++ R R +S R
Sbjct: 16 GLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75
Query: 63 ELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSP 122
F ++ SG+L+ DRE+LC A CV+++++++ED ++L I I V D NDN+P
Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135
Query: 123 LFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEY 182
F A ++ + I E + G RF LP A D D G N + SY LSP++HF L + SR +G +Y
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195
Query: 183 PELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKV 242
PELVLE +LDRE+ A H LVLTA DGG P RSG V++ V D NDNAPVF YR V
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255
Query: 243 PETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPP 302
PE P GT L V A D DEG+NGEV YS +L +F ++ +GE++++ +L
Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLL-KFQLNKYTGEIKISENLDYE 314
Query: 303 ET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIAL 361
ET E I+A D G + +TAK+L+ V DVND++PEL +L +PV ED+ GTV+AL
Sbjct: 315 ETGFYEIEIQAEDGGAY--LATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372
Query: 362 FSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSG 421
+V D D + NG+V C + + PF+L S D+YY L+I LDREQ+S Y + +TA+D G
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432
Query: 422 SPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVS 481
SPPLST + VAD+NDN P F Q ++ ENN GAS+ V A DPD +N +
Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492
Query: 482 YELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTI 541
Y L + +G SS +++ S +G + A SFD+EQ QV D G PP S+ V++
Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552
Query: 542 NLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI 600
+LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY +
Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612
Query: 601 SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV 660
+AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+
Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672
Query: 661 PQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ 709
PQ+L D P + S LYLV+A+A +S +FL ++ + +L +
Sbjct: 673 PQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRR 722
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 595 bits (1534), Expect = e-170
Identities = 328/771 (42%), Positives = 473/771 (61%), Gaps = 24/771 (3%)
Query: 8 VLCLWVSC--GAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELY 65
+LC+++ G A Q+ YSVPEETE+G VGN+S DL L ++ R R +S +
Sbjct: 16 LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75
Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125
F V+ SG+L+ DRE+LC ++C L +L++ED L+++ + + ++D NDN+P F
Sbjct: 76 FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135
Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185
+V++ + E PGARF LPNA+D D G N + SY LSP+ +F L + R DG++ PEL
Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195
Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245
VLE +LDRE+ A HLL+LTA DGG P R G + ++V+D ND+ P+F +SVYR VPE
Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255
Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPET 304
+GT + V A DPDEG NGEV YS N +++ F + ++GEVQV SL
Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRN-MESKASEIFQLDSQTGEVQVRGSLDFEKYR 314
Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364
E I+ +D G GL +T +L+ V DVND+APE+ + N + E++ PGTVIAL +V
Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372
Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424
+D+D NG+V C + + PF+L ++ NYY L+ LDRE + Y + +TA+D GSPP
Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432
Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484
LS + ++VAD NDN P FP ++ ENN GAS+ V A DPD +N LV+Y L
Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492
Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544
D +G SS +++ S++G + A SFD+EQ R +V RD G PP S+ V+++LF
Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552
Query: 545 VVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603
V+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +A
Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKA 612
Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663
S+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++
Sbjct: 613 SEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEV 672
Query: 664 LPDFEDVWE-PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCC 719
L D + + S +LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 673 LADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKS--------- 723
Query: 720 RSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770
L S+ TS + V V+ QTY + SL S + L+
Sbjct: 724 ----RLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLI 770
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 590 bits (1522), Expect = e-168
Identities = 371/954 (38%), Positives = 524/954 (54%), Gaps = 52/954 (5%)
Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67
+L L+ G GQ+ Y VPEE++ G VGN++ D L ++S+R + + +F
Sbjct: 17 LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
Query: 68 VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127
VDL SG L+++ P DRE LC A+C++ + V E PLE+++ + ++D ND++P FP
Sbjct: 77 VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
Query: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187
+ L I E PG RF L AQD D GSN I SY LS ++HF LD+ R DGS PEL+L
Sbjct: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
Query: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247
EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR V E+AP
Sbjct: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
Query: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307
G VL ++ A DPD G +G V + S T +R+ F +HP +G++ + LGP + E
Sbjct: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313
Query: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363
Y E ARD G + L V++ DVND+AP + + +PE A PGTV+AL S
Sbjct: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373
Query: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423
V+D D SNG V + PF L ++F N +SL+ GPLDRE S Y +++TASD+G+P
Sbjct: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433
Query: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483
PLST RTI ++++DVNDN P+F Q E+FV ENN PG L + A DPD G N L+SY
Sbjct: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493
Query: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543
LL+ + SASS +++ +GA+ A SFD+EQ + F+V+ RD G PP S+TVT+ L
Sbjct: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553
Query: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603
FV+D NDN P +L P R GS+ + +P S GHL+TKV A D DSG NAW+SY + A
Sbjct: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663
D SLF +S GE+RTA + +P D Q++V+VV+D G PPLS+SVTL V L +
Sbjct: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
Query: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLG--------CLLFFVCTKLHQSPGCCA 715
+PD + P S LYL ++L I F+ G CL C G CA
Sbjct: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCA 732
Query: 716 -QSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGE 774
+ R E L + ++ + I V S AS SD+ ++
Sbjct: 733 CLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPS 792
Query: 775 YNAADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVH 834
A G + SC G + P PN DWR+S + R G S +
Sbjct: 793 ---------APMAGEPVRPSCPPSDLLYG----LEQAP--PNTDWRFSQAQRPGTSGSQN 837
Query: 835 LEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG 887
++ G P+ Q+ T ++SA+ EA + S +G G + + +YGP
Sbjct: 838 GDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQ 888
Query: 888 NPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 889 FTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 938
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 590 bits (1522), Expect = e-168
Identities = 366/943 (38%), Positives = 528/943 (55%), Gaps = 45/943 (4%)
Query: 11 LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDL 70
LW GAAA Q+ YS+PEE E+G VGN+ DL L ++ R +S R F ++
Sbjct: 23 LW---GAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNP 79
Query: 71 PSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQ 130
+G+LV DRE+LC C++++++++ED L L+ + + ++D NDN+P F +++
Sbjct: 80 RNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELE 139
Query: 131 LHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKA 190
+ I E P +RF L D D G N + + LS + HF +D+ S G +YPELVLE
Sbjct: 140 VKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGT 199
Query: 191 LDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGT 250
LDRE A + LVLTA DGG P RS AQ+ + V+D NDN P+F + VYR VPE P GT
Sbjct: 200 LDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGT 259
Query: 251 VLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPETLLEAY 309
+ V A D DEG +GEV YS T+ ++ F ++ +GE+ +A+L + E
Sbjct: 260 PVLAVTATDQDEGVHGEVTYSFVKITE-KISQIFCLNVLTGEISTSANLDYEDSSFYELG 318
Query: 310 IEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDL 369
+EARD GL AK+L+ + DVND+ PE+ + S + E A PGTVIALF V D D
Sbjct: 319 VEARDGP--GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDS 376
Query: 370 DSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRR 429
NG V C + + PF+L S NYY L+ + LDRE++ Y + +TA+D G+PPLST
Sbjct: 377 GLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTET 436
Query: 430 TITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVIS 489
I+++VAD NDN P FP ++V ENN GAS+ V A DPD+ +N VSY L +
Sbjct: 437 IISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTL 496
Query: 490 EGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRN 549
+G SS +++ S +G + A SFD+EQLR V D G PP S+ V+++LFV+D+N
Sbjct: 497 QGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQN 556
Query: 550 DNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSL 608
DN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ L
Sbjct: 557 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 616
Query: 609 FRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFE 668
F + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++ +P +L D
Sbjct: 617 FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLG 676
Query: 669 DVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLR 726
+ EP + S LYLV+A+A +S +FL ++ + +L Q +S
Sbjct: 677 SL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRL--------QRWHKSRLLQA 727
Query: 727 YGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLRNLATG 786
G + S P S + V V QTY + SL S S L+ + N AD
Sbjct: 728 SGGGLASMP--GSHFVGVEGVRAFLQTYSHEVSLTADS-RKSHLIFPQPNYADTLINQES 784
Query: 787 VGLNLPISCIQ-IRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGP 845
+ P+ Q + KG+ + P PN DWR+S + R G S + ++ G
Sbjct: 785 YEKSEPLLITQDLLETKGEPRQLQQAP--PNTDWRFSQAQRPGTSGSQNGDDTGT----- 837
Query: 846 GGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELP 898
P+ Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 838 -WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYR 892
Query: 899 DKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 893 QNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 588 bits (1515), Expect = e-167
Identities = 357/935 (38%), Positives = 526/935 (56%), Gaps = 38/935 (4%)
Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76
A AG++ YSV EET++G VG+++ DL L ++ R R +S R F ++ SG+LV
Sbjct: 26 AWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLV 85
Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136
DRE++C A C++ +++++ED + L+ I + ++D NDN P F ++ + I E
Sbjct: 86 TAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMEN 145
Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196
PG RF L A D D G+N + SY LSP++HF L + S D ++YPELVLE+ LDRE+
Sbjct: 146 TAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEE 205
Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256
H LVLTA DGG P RS A + + VVD ND+ PVF Y+ VPE P GT L V
Sbjct: 206 RVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVH 265
Query: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLEAYIEARDE 315
A+D DEG NGEV YS T +L FH++ +GE+ L ET E ++A+D
Sbjct: 266 AIDLDEGVNGEVTYSFRKIT-PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG 324
Query: 316 GVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRV 375
G + AK+L+ V DVND+APE+ +LS+ +PED GTVIALF ++D D NG V
Sbjct: 325 P--GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEV 382
Query: 376 ICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSV 435
C + PF+L S DNYY L+ LDRE +S Y + + A+D G+PPLS I + V
Sbjct: 383 TCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQV 442
Query: 436 ADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSAS 495
AD NDN P FP +++AENN GAS+ V AQD D N ++Y L + +G S
Sbjct: 443 ADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVS 502
Query: 496 SLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVI 555
S +++ S +G + A SFD+EQLR +V D G PP S+ ++++LFV+D+NDN P I
Sbjct: 503 SYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEI 562
Query: 556 LFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISAN 614
L+P LP +GS +E+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF +
Sbjct: 563 LYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLY 622
Query: 615 IGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPG 674
GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L D +
Sbjct: 623 TGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSD 682
Query: 675 GQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMVS 733
G + LYLV+A+A +S +FL +L + +L + + L+ ++
Sbjct: 683 GPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRR---------WHKSRLLQASEGGLA 733
Query: 734 NPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLRNLATGVGLNLPI 793
N TS + + V+ QTY + SL S + L+ L + + + +
Sbjct: 734 N-VPTSHFVGMDGVQAFLQTYSHEVSLTADSRKSHLIFPQPNYVDMLISQESCEKNDSLL 792
Query: 794 SCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 853
+ + + K + ++ P PN DWR+S + R G S + ++ G P+ Q+
Sbjct: 793 TSVDFQECKENLPSIQQAP--PNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFD 844
Query: 854 T-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGS 906
T ++SA+ EA + S +G G + + +YGP Q P + IPGS
Sbjct: 845 TEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGS 900
Query: 907 PAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
A ++ + K+ G K+++ KK+KK
Sbjct: 901 NATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 587 bits (1512), Expect = e-167
Identities = 320/779 (41%), Positives = 476/779 (61%), Gaps = 17/779 (2%)
Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRF--LSSHRELY 65
+L L + G AA QL YSVPEE G VGN++ L L + R L + Y
Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
Query: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFP 125
+DL SG L V E DRE LC + C+L+ +++ +P+ + + + +LD NDNSP FP
Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
Query: 126 AGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPEL 185
+ QL + E + PGARF + +AQD D G+N + +Y LSPS+HF LD+ + S+ EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
Query: 186 VLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPET 245
VL K LDREQ A H LVLTA DGG+PARSG AQ+++ V+DTNDN+P F++S YR ++ E
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
Query: 246 APNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPE-T 304
+P GT++ ++ A DPDEGSNGE++YSLS+ T R F + +GEV+V L E +
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
Query: 305 LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSV 364
+ Y++A D G +A K+LV++ DVND+APE+ L +PVPE+A P T++A+ SV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
Query: 365 KDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPP 424
D+D N +V G+ + PF+L F N Y+L++ GPLDRE+++ Y + +TA+D G P
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRLNG-FGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
Query: 425 LSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYEL 484
L++ RT+ V ++D+NDN P+F + +++ ENN PG L V A DPD +N V+Y L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
Query: 485 LDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLF 544
L+ +G +S +++ S+SG++ A SFD+E+ R F VE +D G PP S+TVT N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
Query: 545 VVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRAS 604
VVD ND+ P IL+P N S E+VPR+A G+LVTKV+A D+DSG NAWL YH+++ S
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
Query: 605 DSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLL 664
D LF++ + GE+RT R + + VVVRD+G+P LS+SV + V + + V ++L
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
Query: 665 PDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQ----SPGCCAQSCC- 719
PD + + S LYL+IAL+ +SF+FL ++ K ++ CC C
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748
Query: 720 --RSTEDL------RYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770
RS +L +++ + I+V L++TY Y+A L GS +++ +
Sbjct: 749 RERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 583 bits (1503), Expect = e-166
Identities = 330/786 (41%), Positives = 472/786 (60%), Gaps = 26/786 (3%)
Query: 1 MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
+V G+ + LW + Q+ YSVPEE E+G VG++S DL L ++ R R +
Sbjct: 13 LVLLGILLGTLWET---GCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPR 69
Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
R F ++ SG+LV DRE+LC C L D+++ED ++++ + + V D NDN
Sbjct: 70 GRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDN 129
Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
+P F ++++ I E RF LP+A D D G N + SY LSP+ HF L + + DGS
Sbjct: 130 APYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGS 189
Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
+YPELVL++ALDRE++A H LVLTA DGG P R+G A++ ++V+D NDNAP F + YR
Sbjct: 190 KYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRA 249
Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
VPE GT L V A DPDEG N EV+YS + F + SG + L
Sbjct: 250 SVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELD 308
Query: 301 PPET-LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359
E+ + ++A D G ++ AK+L+ V DVND+APE+ +L++ VPE++ GT+I
Sbjct: 309 HEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLI 366
Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419
AL +V D+D + NG+VIC + PF+L S+ NYYSL+ D LDREQ+ Y + +TA+D
Sbjct: 367 ALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATD 426
Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479
G+PPLST I+++VAD NDN P FPQ ++ ENN G SL V A DPD +N
Sbjct: 427 RGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQ 486
Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539
++Y L + +G S SS +++ S +G + A +SFD+EQ R +V RD G PP S+ V
Sbjct: 487 ITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNV 546
Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598
+++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY
Sbjct: 547 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658
+ +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 659 SVPQLLPDFEDVWEP-GGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCC 714
S+PQ+L D + P + S LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 667 SIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQ 726
Query: 715 AQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGE 774
A G + P S + V V+ QTY + SL S S L+ +
Sbjct: 727 AS-----------GGGLTGAP--ASHFVGVDGVQAFLQTYSHEVSLTTDS-RKSHLIFPQ 772
Query: 775 YNAADL 780
N AD+
Sbjct: 773 PNYADM 778
>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
[Homo sapiens]
Length = 929
Score = 583 bits (1502), Expect = e-166
Identities = 358/934 (38%), Positives = 516/934 (55%), Gaps = 51/934 (5%)
Query: 22 LEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPA 81
+ YS+PEE +G VGNL+ DL L +S+R R S +L+F VD SG+L+V++
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRV--SAEKLHFSVDAQSGDLLVKDRI 90
Query: 82 DREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGA 141
DREQ+C+ + C L + V+E+PL + + + + D ND++P F ++ L I E ++ G
Sbjct: 91 DREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLGM 150
Query: 142 RFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLL 201
L +A+D D N + Y LSP+++F L DG +YPELVL+K LDRE ++ H L
Sbjct: 151 GTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHL 210
Query: 202 VLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPD 261
VLTA DGG P RSG AQ+ I+V+D NDN PVF + VYR + E P GT + RV+A D D
Sbjct: 211 VLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQD 270
Query: 262 EGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAY---IEARDEGVF 318
EG N E+ YS + +H F + +G + L E +E Y IEA+D G
Sbjct: 271 EGINSEITYSFFGVAD-KAQHVFSLDYTTGNILTQQPLDFEE--VERYTINIEAKDRG-- 325
Query: 319 GLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICG 378
L++ K++VEV D ND++PE+ +LS+ + ED+ PG V+ALF +D+D NG V C
Sbjct: 326 SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCS 385
Query: 379 MSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADV 438
+S PF++ +S +NYY L+ D LDREQ EY V I A+D G PPLS+ +TIT+ + DV
Sbjct: 386 LSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDV 445
Query: 439 NDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLL 498
NDN P F Q + V ENN PGAS+ +V A DPD G NG VSY L+ E + SS +
Sbjct: 446 NDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYV 505
Query: 499 AVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFP 558
+V + SG + A+ +FD EQLR F ++ RD G P SA V++ + V DRNDN P +L+P
Sbjct: 506 SVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYP 565
Query: 559 -LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGE 617
L +GS + VPR+A+ G+LVTKVVA DADSG NAWLSYH+ +AS+ LF + GE
Sbjct: 566 ALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGE 625
Query: 618 LRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPGGQL 677
+R R + D+V+QR++V VRD G PPLS++ TL ++ ++S+ ++LPDF D P
Sbjct: 626 VRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQ 685
Query: 678 SAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMVSNPCM 737
+ YLV+ALA IS LFL ++ + +L QS A C S C
Sbjct: 686 AEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFESV------------LCS 733
Query: 738 TSATIDVTTVERLSQTYLYRASLGLGSDNN---SLLLRGEYNAADLRNLATGVGLNLPIS 794
S + + Y Y + G N + ++ A NL L I
Sbjct: 734 KSGPVGPPNYSEGTLPYAYNFCVP-GDQMNPEFNFFTSVDHCPATQDNLNKDSMLLASIL 792
Query: 795 CIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT 854
+ K + PN DWR+S + R G S + ++ G P+ Q+ T
Sbjct: 793 TPSVEADK----KILKQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQFDT 842
Query: 855 -------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSP 907
++SA+ EA + S +G G + + +YGP Q P + IPGS
Sbjct: 843 EMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSN 898
Query: 908 AIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
A ++ + K+ G K+++ KK+KK
Sbjct: 899 ATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 929
>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 581 bits (1498), Expect = e-165
Identities = 361/940 (38%), Positives = 515/940 (54%), Gaps = 48/940 (5%)
Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76
A AGQ+ YSV EE +RG VGN++ DL L A++ + R +S R F ++ SG+LV
Sbjct: 26 ARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRSQLFALNPRSGSLV 85
Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136
DRE+LC A C+L ++++LED L ++ + + + D NDN+P F +++L I E
Sbjct: 86 TANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPRFGVEELELKISET 145
Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196
TPG R L NA D D G N + Y+L+P+ HF LD+ DG++YPELVLE++LDRE+
Sbjct: 146 TTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKYPELVLERSLDREEE 205
Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256
A H LVL A DGG P SG +++ + V+D NDNAPVF + YR +PE GT + V
Sbjct: 206 AVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILTVT 265
Query: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEARDE 315
A D DEG +V Y L S E F + SGE+ + L + T E IEA+D
Sbjct: 266 ATDADEGYYAQVVYFLEKS-PGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDG 324
Query: 316 GVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRV 375
GL + AK++V V DVND+APE + ++ V ED+ PGT+I LF+V D D N
Sbjct: 325 P--GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSGQNAFT 382
Query: 376 ICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSV 435
C + PF+L S DNYY L+ LDREQ S Y + +TA D G+P LST I + V
Sbjct: 383 TCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQV 442
Query: 436 ADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSAS 495
AD+NDN P F + ++ ENN GAS+ V A DPD N V+Y + +G S
Sbjct: 443 ADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLS 502
Query: 496 SLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVI 555
S +++ S +G + A SFD+EQLR V RD G PP S+ V+++LFV+D+NDN P I
Sbjct: 503 SYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSLSLFVLDQNDNAPEI 562
Query: 556 LFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISAN 614
L+P P +GS VE+ PRSA G+LVTKVVA D DSG NAWLSYH+ +AS+ LF + +
Sbjct: 563 LYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLH 622
Query: 615 IGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPG 674
GE+RTAR +L DA+KQ +VV ++DHG PPLS++VTL V +++ +P +L D + EP
Sbjct: 623 TGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLTVAVADRIPDILADLGSL-EPS 681
Query: 675 G--QLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMV 732
S LYLV+A+A +S +FL ++ + +L + L S
Sbjct: 682 AIPNDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRR----------WHKSRLLQASGGS 731
Query: 733 SNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL----RNLATGVG 788
+S + V V QTY + SL S S L+ + N AD +
Sbjct: 732 LTGMQSSHFVGVDGVRAFLQTYSHEVSLTADS-RKSHLIFPQPNYADTLISQESCEKKDF 790
Query: 789 LNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP 848
L+ P S ++ + + PN DWR+S + R G S + ++ G P
Sbjct: 791 LSAPQSLLE-----EEREETFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WP 839
Query: 849 DQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKF 901
+ Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 840 NNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNV 895
Query: 902 IIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 896 YIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
[Homo sapiens]
Length = 927
Score = 581 bits (1498), Expect = e-165
Identities = 354/942 (37%), Positives = 523/942 (55%), Gaps = 53/942 (5%)
Query: 15 CGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGN 74
CGA + Q+ Y++PEE G VG L+ DL L + +R R + E YF V L SG+
Sbjct: 24 CGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSA---EDYFNVSLESGD 80
Query: 75 LVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIP 134
L+V DRE++C K C L ++ V E+P+ + + + + D NDN+P F A + L I
Sbjct: 81 LLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEIC 140
Query: 135 EFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDRE 194
E PG +F+L +AQD D N + Y+++P+Q+F L DGS+YP L+LEK LDRE
Sbjct: 141 ESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDRE 200
Query: 195 QRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFR 254
+++H L+LTA DGG P SG + I V D NDNAPVF + VYR + E P GT + R
Sbjct: 201 HQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR 260
Query: 255 VQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAY-IEAR 313
V A D DEG N E+ Y+ NS + F+++P +G++ +L ET +EA+
Sbjct: 261 VMATDQDEGINAEITYAFLNSPIST--SLFNLNPNTGDITTNGTLDFEETSRYVLSVEAK 318
Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373
D GV + + +E+ D ND+APE+ F++ SN +PED+ GTVIAL V+D+D NG
Sbjct: 319 DGGVH--TAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQNG 376
Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433
V C PF+L ++ NYY L+I G L+REQ ++Y V I A+D G P LS+R +IT+
Sbjct: 377 MVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSITL 436
Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493
++D+NDN P F Q + V+ENN PGAS+ +V A DPDLG NG VSY +L E
Sbjct: 437 HISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEPRE 496
Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553
S ++V SG + A+ +FD EQLR F ++ RD G P SA V++ + V D NDN P
Sbjct: 497 LLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAP 556
Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612
+L+P L +GS ++VPR+A G+LVTKVVA DADSG NAWLSYH+ +AS+ LF +
Sbjct: 557 RVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLG 616
Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672
GE+RTAR + DA +QR++V VRD G PPLS++ TL ++ ++S+ ++LPD D E
Sbjct: 617 LRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRPE 676
Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMV 732
P + YLV+ALA IS LFL ++ + +L +S + C ++ + G +
Sbjct: 677 PSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLCSKSGPGVP 736
Query: 733 SNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLR-NLATGVGLNL 791
N T Y +L + S + + E+N+ +L +A L
Sbjct: 737 PN--------------HSEGTLPYSYNLCIASHS----AKTEFNSLNLTPEMAPPQDLLC 778
Query: 792 PISCIQIRNRKGDH-----ANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPG 846
+ + DH ++++ PN DWR+S + R G S + ++ G
Sbjct: 779 DDPSMVVCASNEDHKIAYDPSLSSHQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------ 832
Query: 847 GPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPD 899
P+ Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 833 WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQ 888
Query: 900 KFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 889 NVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 927
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 580 bits (1494), Expect = e-165
Identities = 363/950 (38%), Positives = 517/950 (54%), Gaps = 43/950 (4%)
Query: 9 LCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGV 68
LC W G +GQL YSV EE+E G VGN++ DL L + SR + S YF +
Sbjct: 21 LCCW---GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSL 77
Query: 69 DLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGD 128
L SG L V + DRE LC A +C+L +V E PLEL ++ + +LD NDNSP F +
Sbjct: 78 SLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPE 137
Query: 129 VQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLE 188
++ I E GARF L +AQD D G+N + Y+LSP+ HF L++ + DG +PELVLE
Sbjct: 138 REMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLE 197
Query: 189 KALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPN 248
+ LDRE +A H LVLTA DGG PARSG +++IV+D NDNAP F+ SV R +PE AP
Sbjct: 198 QQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPI 257
Query: 249 GTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLE 307
GT+L R+ A DPDEG+NG++ YS + T +R+ F + P SG + V + E+ E
Sbjct: 258 GTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYE 317
Query: 308 AYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDE 367
+ ARD+G + + V+V DVND+APE+ +L+NPV E GTV+ LF+V+D
Sbjct: 318 IHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDR 377
Query: 368 DLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLST 427
D NG V +S PFQ+ S +N+YSLL PLDRE S Y + + ASD+GSP L
Sbjct: 378 DSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
Query: 428 RRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDV 487
TI ++++DVNDN P F Q ++ EN PG+ L V A DPD G N ++Y ++
Sbjct: 437 HLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGN 496
Query: 488 ISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVD 547
+G ASS + V G I A+ +FD+E L+ V RD G PP A ++++FV+D
Sbjct: 497 QVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLD 556
Query: 548 RNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYH-ISRASDS 606
NDN P +L P P + +PRSA G LVTKV A DAD+G NAWLSY + +++
Sbjct: 557 ENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAP 616
Query: 607 SLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPD 666
LF +S + GE+RTAR +L D+ Q+VVV+VRD+GDP LSS+ T+ ++L + P+ +P
Sbjct: 617 GLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPK 676
Query: 667 FEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFF--VCTKLHQSPGCCAQSCCRSTED 724
D + S LYL++ALA +S L L F C + + CCR +
Sbjct: 677 SSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRRQDS 736
Query: 725 LRYGSKMVSNPCM------TSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAA 778
S+P + T ++VT SQ++ YR SD +
Sbjct: 737 PSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTF------- 789
Query: 779 DLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEA 838
LR L+ L + IR+R + + PN DWR+S + R G S + ++
Sbjct: 790 -LRPLSVQQPTALALEPDAIRSR-SNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDT 847
Query: 839 GILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQ 891
G P+ Q+ T ++SA+ EA + S +G G + + +YGP Q
Sbjct: 848 GT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQ 898
Query: 892 SGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941
P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 899 HVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 944
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 579 bits (1492), Expect = e-165
Identities = 318/720 (44%), Positives = 437/720 (60%), Gaps = 16/720 (2%)
Query: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67
+L L+ G GQ+ Y VPEE++ G VGN++ D L ++S+R + + +F
Sbjct: 17 LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
Query: 68 VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127
VDL SG L+++ P DRE LC A+C++ + V E PLE+++ + ++D ND++P FP
Sbjct: 77 VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
Query: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187
+ L I E PG RF L AQD D GSN I SY LS ++HF LD+ R DGS PEL+L
Sbjct: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
Query: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247
EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR V E+AP
Sbjct: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
Query: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307
G VL ++ A DPD G +G V + S T +R+ F +HP +G++ + LGP + E
Sbjct: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313
Query: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363
Y E ARD G + L V++ DVND+AP + + +PE A PGTV+AL S
Sbjct: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373
Query: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423
V+D D SNG V + PF L ++F N +SL+ GPLDRE S Y +++TASD+G+P
Sbjct: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433
Query: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483
PLST RTI ++++DVNDN P+F Q E+FV ENN PG L + A DPD G N L+SY
Sbjct: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493
Query: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543
LL+ + SASS +++ +GA+ A SFD+EQ + F+V+ RD G PP S+TVT+ L
Sbjct: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553
Query: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603
FV+D NDN P +L P R GS+ + +P S GHL+TKV A D DSG NAW+SY + A
Sbjct: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
Query: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663
D SLF +S GE+RTA + +P D Q++V+VV+D G PPLS+SVTL V L +
Sbjct: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
Query: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLG--------CLLFFVCTKLHQSPGCCA 715
+PD + P S LYL ++L I F+ G CL C G CA
Sbjct: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCA 732
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 577 bits (1486), Expect = e-164
Identities = 360/961 (37%), Positives = 530/961 (55%), Gaps = 56/961 (5%)
Query: 1 MVGCG-VAVLCLWVSC--GAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRF 57
+ GC + +LCL + A AG + YSVPEET++G VGN++ DL L ++ R
Sbjct: 7 LTGCSRLMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRI 66
Query: 58 LSSHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDT 117
+S R F ++ SG+L+ DRE+LC C++++++++ED ++L + + ++D
Sbjct: 67 VSRGRMPLFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDI 126
Query: 118 NDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRV 177
NDN+P F +++ + E TPG R +LP QD D G N + SY LS + HF LD+
Sbjct: 127 NDNTPQFQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGA 186
Query: 178 DGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSV 237
DG ++PE+VL+ LDRE+ A H L+LTA DGG P RSG ++ I VVD NDN P F ++
Sbjct: 187 DGPQHPEMVLQSPLDREEEAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQ 246
Query: 238 YRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAA 297
Y VPE P GT L V A DPDEG+NGEV YS N + F + +GE+
Sbjct: 247 YHINVPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIFRLDSYTGEISNKE 305
Query: 298 SLGPPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGT 357
L E + + +E + + GL + K+L++V DVND+APE+ +++ VPE+ PGT
Sbjct: 306 PLDFEEYKMYS-MEVQAQDGAGLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGT 364
Query: 358 VIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITA 417
+IAL SV D+D NG C + PF+L DNYY L+ + LDRE IS Y + ITA
Sbjct: 365 IIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITA 424
Query: 418 SDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKN 477
D G+P LST I++ V D+NDN+P F Q ++ ENN GAS+ V A D D +N
Sbjct: 425 IDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNEN 484
Query: 478 GLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSA 537
++Y L++ +G S+ L++ S +G + A SFD+EQ R +V RD G PP S+
Sbjct: 485 AQITYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSS 544
Query: 538 TVTINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWL 596
V+++LF++D+NDN P IL+P LP +GS VE+ P SA G+LVTKVVA D DSG NAWL
Sbjct: 545 NVSLSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWL 604
Query: 597 SYHISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLL 656
SY + +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +
Sbjct: 605 SYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAV 664
Query: 657 SNSVPQLLPDFEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSP 711
++ + +L D + EP + S LYLV+A A +S +FL ++ + +L H+S
Sbjct: 665 ADRISDILADLGSL-EPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHKSR 723
Query: 712 GCCAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLL 771
A G + S P S + V V QTY + SL S S L+
Sbjct: 724 LLQAS-----------GGGLASMP--GSHFVGVDGVRAFLQTYSHEVSLTADS-RKSHLI 769
Query: 772 RGEYNAADL----RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRA 827
+ N AD + L+ P S ++ D + PN DWR+S + R
Sbjct: 770 FPQPNYADTLISQESCEKKGFLSAPQSLLE------DKKEPFSQQAPPNTDWRFSQAQRP 823
Query: 828 GMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSW 880
G S + ++ G P+ Q+ T ++SA+ EA + S +G G +
Sbjct: 824 GTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGL 874
Query: 881 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK 940
+ +YGP Q P + IPGS A ++ + K+ G K+++ KK+K
Sbjct: 875 SARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEK 930
Query: 941 K 941
K
Sbjct: 931 K 931
>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
[Homo sapiens]
Length = 829
Score = 575 bits (1483), Expect = e-164
Identities = 330/777 (42%), Positives = 460/777 (59%), Gaps = 26/777 (3%)
Query: 3 GCGVAVLC--LWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS 60
G G+A+LC L C +GQ+ YSV EE ++G VGN++ DL L ++ R R +S
Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69
Query: 61 HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN 120
R F ++ SG+LV E DRE+LC C++ ++++ED L++ ++ I + D NDN
Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129
Query: 121 SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS 180
+P FP ++++ I E PG RF + A D D G N + +Y LSP+ +F L + S +G+
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189
Query: 181 EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT 240
+YPELVLE+ALDRE++ H LVL A DGG P SG+ + +IV+D NDN P+F + YR
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249
Query: 241 KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG 300
V E P GT L V A DPDEG N +V Y L + ++ FH++ SGEV + SL
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308
Query: 301 PPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359
+ + E IEA+D GL S AK+LV V DVND+APE+ +L++ VPE+ G I
Sbjct: 309 YEDAMFYEIKIEAQDGP--GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366
Query: 360 ALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASD 419
AL V D D NG+V + PF+L S D YY L+ LDREQISEY + + ASD
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426
Query: 420 SGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGL 479
GSPPLST IT+ V D+NDN P FP ++ ENN GAS+ V AQDPD N
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486
Query: 480 VSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATV 539
++Y L + +G SS +++ S++G + A SFD+EQ R V D G PP S+ V
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Query: 540 TINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598
++NLFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 599 HISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSN 658
+ +AS+ LF + + GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 659 SVPQLLPDFEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGC 713
+P +L D + EP + S LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 667 RIPDILADLGSL-EPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLL 725
Query: 714 CAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770
A G + S P S + V QTY + SL S + L+
Sbjct: 726 QAS-----------GGGLASTP--GSHFVGADGVRAFLQTYSHEVSLTADSRKSHLI 769
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 574 bits (1480), Expect = e-163
Identities = 326/769 (42%), Positives = 460/769 (59%), Gaps = 24/769 (3%)
Query: 9 LCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGV 68
L L V A Q+ YSV EE E G VGN++ DL L ++ R R +S R F +
Sbjct: 18 LLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFAL 77
Query: 69 DLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGD 128
+ SG LV DRE+LC CV +++LED +++ ++ + ++D NDN P F
Sbjct: 78 NPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQ 137
Query: 129 VQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLE 188
++ + E PGARF LP A D D G N + Y L+ + +F LD+ S DG +YPELVLE
Sbjct: 138 REIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLE 197
Query: 189 KALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPN 248
+ALDRE+ A H LVLTA DGG P RSG A++ II+VDTNDNAPVF + Y V E P
Sbjct: 198 RALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPV 257
Query: 249 GTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLE 307
GT L V+A DPDEG+NG+V YS + ++ F ++ SG++ + L ++ +
Sbjct: 258 GTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYD 316
Query: 308 AYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDE 367
+EA D GL + +K+LV V D ND+APE+ +L++ V E ++PGTVIALF+V D
Sbjct: 317 IDVEAHDGP--GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDS 374
Query: 368 DLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLST 427
D NG V C + PF L ++ NYY LL LDRE++SEY + +TA+D G+PPLST
Sbjct: 375 DSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLST 434
Query: 428 RRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDV 487
I++ V D+NDN P FP ++ ENN GAS+ + AQDPD G N ++Y L +
Sbjct: 435 ETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAED 494
Query: 488 ISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVD 547
+G SS +++ S++G + A SFD+EQ R + D G PP S+ V+++LFV+D
Sbjct: 495 TFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLD 554
Query: 548 RNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDS 606
+NDN P IL+P P +GS VE+ PRSA +G+LVTKVVA D DSG NAWLSY + ++S+
Sbjct: 555 QNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEP 614
Query: 607 SLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPD 666
LF + + GE+RTAR +L DA+KQR+VVVV+DHG PPLS++VTL V +++S+P +L D
Sbjct: 615 GLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLAD 674
Query: 667 FEDVWEPGGQL--SAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRS 721
+ +P S LYLV+A+A +S +FL + + KL H+S A+
Sbjct: 675 LGSL-KPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAE----- 728
Query: 722 TEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770
GS++ P S + V V QTY + SL S + L+
Sbjct: 729 ------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 769
>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 572 bits (1473), Expect = e-163
Identities = 331/771 (42%), Positives = 460/771 (59%), Gaps = 31/771 (4%)
Query: 20 GQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVRE 79
GQ+ YSVPEET++G VGN+S DL L ++ R +S R F ++ SG+L+
Sbjct: 29 GQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAG 88
Query: 80 PADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTP 139
DRE+LC C++ + ++ED +L + I ++D NDN+P F D+++ I E P
Sbjct: 89 RIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVP 148
Query: 140 GARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATH 199
GAR+ LP A D D G N + SY LSP+ HF LD+ + +G+ PELVLE+ALDRE+ A H
Sbjct: 149 GARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208
Query: 200 LLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALD 259
LVLTA DGG P RS ++ + V+DTNDNAPVF +YR KV E P GT L V A D
Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLTVTASD 268
Query: 260 PDEGSNGEVQYSLS--NSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEARDEG 316
PDEG NG+V Y N Q L F ++ +GE+ +A SL E + E I+A D G
Sbjct: 269 PDEGINGKVAYKFRKINEKQTPL---FQLNENTGEISIAKSLDYEECSFYEMEIQAEDVG 325
Query: 317 VFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVI 376
L KLL+ V DVND+ PE+ +L +PV E++ PGTVIA SV D+D NG+V+
Sbjct: 326 --ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVV 383
Query: 377 CGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVA 436
C PF+L S NYY L+ LDRE +S Y + + ASD G+PPLST I + VA
Sbjct: 384 CYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVA 443
Query: 437 DVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASS 496
D+NDN P FP ++ ENN GAS+ + A DPD +N V+Y + + +G SS
Sbjct: 444 DINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSS 503
Query: 497 LLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVIL 556
+++ S +G + A SFD+EQ+R V D G PP S+ ++++LFV+D+NDN P IL
Sbjct: 504 YISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEIL 563
Query: 557 FP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANI 615
+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF + +
Sbjct: 564 YPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHT 623
Query: 616 GELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDV---WE 672
GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P++L + + +
Sbjct: 624 GEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVD 683
Query: 673 PGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKL---HQSPGCCAQSCCRSTEDLRYGS 729
P S+ LYLV+A+A IS +FL + + +L H+S R +D G
Sbjct: 684 PND--SSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKS---------RLLQD--SGG 730
Query: 730 KMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780
++V P S + V V+ QTY SL S S L+ + N AD+
Sbjct: 731 RLVGVP--ASHFVGVEEVQAFLQTYSQEVSLTADS-RKSHLIFPQPNYADM 778
>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
[Homo sapiens]
Length = 828
Score = 571 bits (1472), Expect = e-162
Identities = 328/759 (43%), Positives = 449/759 (59%), Gaps = 20/759 (2%)
Query: 17 AAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLV 76
A A Q+ YSVPEETE+G VGN+S DL L ++ R R +S R F ++ SG LV
Sbjct: 26 ARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRTQLFSLNPRSGTLV 85
Query: 77 VREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEF 136
DRE+LC C++ + +++ED ++L+ I I V D ND++P F A +++ I E
Sbjct: 86 TAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEI 145
Query: 137 LTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQR 196
PGAR+ LP A D D G N + SY LSP+ HF L++ + +G+ PELVLE+ALDRE+
Sbjct: 146 AVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEA 205
Query: 197 ATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQ 256
H LVLTA DGG P RS ++ + V+DTNDNAPVF + +YR KV E P GT L
Sbjct: 206 TAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTAT 265
Query: 257 ALDPDEGSNGEVQYSL--SNSTQAELRHRFHVHPKSGEVQVAASLGPPE-TLLEAYIEAR 313
A D DEG NG+V Y N Q+ L F ++ +GE+ A SL E + E I+A
Sbjct: 266 ASDLDEGINGKVAYKFWKINEKQSLL---FQLNENTGEISTAKSLDYEECSFYEMEIQAE 322
Query: 314 DEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNG 373
D G GL K+L+ V DVND+ PE+ +L +PV EDA GTVI LF+ D D NG
Sbjct: 323 DGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDSGKNG 380
Query: 374 RVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433
+V+C + F L S ++YY LL LDRE+ SEY + +TA+D G+PPLST IT+
Sbjct: 381 QVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITL 440
Query: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPS 493
V D+NDN P F Q +++ ENN G S+ V A DPD +N V Y L + +G
Sbjct: 441 QVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSP 500
Query: 494 ASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYP 553
S+ +++ S +G + A SFD+EQ R QV D G PP S+ V++ LFV+D+NDN P
Sbjct: 501 LSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVSLRLFVLDQNDNAP 560
Query: 554 VILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRIS 612
IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAWLSY + +AS+ LF +
Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVG 620
Query: 613 ANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672
+ GE+RTAR +L DA+KQ +VV V+DHG PPLS++VTL V +++S+P +L D +
Sbjct: 621 LHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADSIPDILADLGSLQI 680
Query: 673 PGG-QLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKM 731
P + S LYLV+A+A +S +FL ++ + +L + R+T D G
Sbjct: 681 PADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRH---WHSSHLLRATSDGLAG--- 734
Query: 732 VSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770
TS + V V QTY SL S + L+
Sbjct: 735 ----VPTSHFVGVDGVRAFLQTYSQEFSLTADSRKSHLI 769
>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
[Homo sapiens]
Length = 813
Score = 570 bits (1469), Expect = e-162
Identities = 324/779 (41%), Positives = 456/779 (58%), Gaps = 29/779 (3%)
Query: 3 GCGVAVL---CLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLS 59
GCG +L L C +GQ+ YS+PEE ++G VGN++ DL L ++ R R +S
Sbjct: 9 GCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVS 68
Query: 60 SHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTND 119
R F ++ SG+LV DRE+LC CV+ +++++E+ ++++ + + ++D ND
Sbjct: 69 RGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIND 128
Query: 120 NSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDG 179
N P F ++++ + E G R LP A+D D G N + SY LS + HF LD+ S DG
Sbjct: 129 NFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDG 188
Query: 180 SEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYR 239
+YPELVLE+ LDRE+ H L+LTA DGG P SG + + V+D NDNAP+F S Y
Sbjct: 189 QKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYS 248
Query: 240 TKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASL 299
VPE P GT L + A DPDEG NG++ YS N + ++ F + GE+ SL
Sbjct: 249 VSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEE-KISETFQLDSNLGEISTLQSL 307
Query: 300 GPPET---LLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPG 356
E+ L+E + A+D G L ++AK++V V DVND+APE+ +L++ + ED PG
Sbjct: 308 DYEESRFYLME--VVAQDGGA--LVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPG 363
Query: 357 TVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLIT 416
TVIALFSV D D NG + C + PF+L S DNYY LL LDRE+ S+Y + +T
Sbjct: 364 TVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLT 423
Query: 417 ASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGK 476
D G+PPLST I + VADVNDN PNFPQ V ENN G S+ V A DPD G
Sbjct: 424 VMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGD 483
Query: 477 NGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRS 536
N V+Y L + +G SS +++ S +G + A SFD+EQLR V D G PP S
Sbjct: 484 NARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLS 543
Query: 537 ATVTINLFVVDRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAW 595
+ V+++LFV+D+NDN P IL+P LP +GS VE+ PRSA G+LVTKVVA D DSG NAW
Sbjct: 544 SNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAW 603
Query: 596 LSYHISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVL 655
LSY + +AS+ LF + + GE+RTAR +L DA+KQ +VV V DHG PPLS++ T+ V
Sbjct: 604 LSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVA 663
Query: 656 LSNSVPQLLPDFEDVWEPGGQLSAQ-NLYLVIALACISFLFLGCLLFFVCTKL---HQSP 711
+++ +P +L D + P LYLV+A+A +S +FL ++ + +L H+S
Sbjct: 664 VADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSR 723
Query: 712 GCCAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLL 770
A+ GS++ P S + V V QTY + SL S + L+
Sbjct: 724 LLQAE-----------GSRLAGVP--ASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 769
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,390,614
Number of Sequences: 37866
Number of extensions: 2062360
Number of successful extensions: 14193
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 7176
Number of HSP's gapped (non-prelim): 1056
length of query: 963
length of database: 18,247,518
effective HSP length: 112
effective length of query: 851
effective length of database: 14,006,526
effective search space: 11919553626
effective search space used: 11919553626
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.