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Search of human proteins with 14589856
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589856 protein tyrosine phosphatase type IVA, member 3
isoform 1 [Homo sapiens]
(173 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589856 protein tyrosine phosphatase type IVA, member 3 isof... 360 e-100
gi|14589854 protein tyrosine phosphatase type IVA, member 3 isof... 300 4e-82
gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo... 292 1e-79
gi|18104971 protein tyrosine phosphatase type IVA, member 2 isof... 280 3e-76
gi|169162376 PREDICTED: similar to protein tyrosine phosphatase ... 251 2e-67
gi|239753025 PREDICTED: similar to protein tyrosine phosphatase ... 191 2e-49
gi|18104973 protein tyrosine phosphatase type IVA, member 2 isof... 105 1e-23
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens] 59 2e-09
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens] 59 2e-09
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens] 59 2e-09
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens] 55 3e-08
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens] 55 3e-08
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens] 55 3e-08
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 42 2e-04
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 42 2e-04
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 42 2e-04
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 42 2e-04
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 42 2e-04
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 42 3e-04
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 42 3e-04
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 42 3e-04
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 42 3e-04
gi|56786144 dual specificity phosphatase 23 [Homo sapiens] 42 3e-04
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 42 3e-04
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 42 3e-04
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 42 3e-04
gi|30089952 protein tyrosine phosphatase domain containing 1 pro... 41 5e-04
gi|30089950 protein tyrosine phosphatase domain containing 1 pro... 41 5e-04
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 37 0.007
gi|5729993 protein tyrosine phosphatase, receptor type, E isofor... 36 0.015
>gi|14589856 protein tyrosine phosphatase type IVA, member 3 isoform
1 [Homo sapiens]
Length = 173
Score = 360 bits (923), Expect = e-100
Identities = 173/173 (100%), Positives = 173/173 (100%)
Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
Sbjct: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
Sbjct: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173
ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173
>gi|14589854 protein tyrosine phosphatase type IVA, member 3 isoform
2 [Homo sapiens]
Length = 148
Score = 300 bits (768), Expect = 4e-82
Identities = 148/173 (85%), Positives = 148/173 (85%), Gaps = 25/173 (14%)
Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
Sbjct: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGR
Sbjct: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGR---------- 110
Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173
KRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
Sbjct: 111 ---------------KRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 148
>gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo
sapiens]
Length = 173
Score = 292 bits (747), Expect = 1e-79
Identities = 136/172 (79%), Positives = 152/172 (88%)
Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60
Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
+GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI
Sbjct: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120
Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+
Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172
>gi|18104971 protein tyrosine phosphatase type IVA, member 2 isoform
1 [Homo sapiens]
Length = 167
Score = 280 bits (717), Expect = 3e-76
Identities = 131/169 (77%), Positives = 149/169 (88%), Gaps = 3/169 (1%)
Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+GI
Sbjct: 1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 60
Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
V+DWPFDDGAPPP ++V+DWL+L+K KF E PG CVAVHCVAGLGRAPVLVALALIE G
Sbjct: 61 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 120
Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
MKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H CCV
Sbjct: 121 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCV 166
>gi|169162376 PREDICTED: similar to protein tyrosine phosphatase 4a1
isoform 1 [Homo sapiens]
Length = 170
Score = 251 bits (641), Expect = 2e-67
Identities = 115/169 (68%), Positives = 137/169 (81%)
Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
MN PAPV+V+YK+MRF ITHNPTN TL+ FIE+LKKYGATT+VRVCE TYD T +EK+GI
Sbjct: 1 MNHPAPVKVTYKNMRFPITHNPTNVTLNKFIEELKKYGATTIVRVCEATYDTTLVEKEGI 60
Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
V++WPF DGAPP ++V DWL VK KFCE PG +AV+C+ GLG+APVLVALA +E G
Sbjct: 61 HVLNWPFGDGAPPSNQIVADWLHFVKIKFCEEPGCYIAVNCIVGLGKAPVLVALASVEGG 120
Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
MK+EDA+QFI QKR GA SKQL YLEKY PK RLRFKD ++H CC+
Sbjct: 121 MKHEDAVQFIGQKRSGAFKSKQLLYLEKYHPKMRLRFKDSNSHINNCCI 169
>gi|239753025 PREDICTED: similar to protein tyrosine phosphatase 4a1
isoform 2 [Homo sapiens]
Length = 139
Score = 191 bits (486), Expect = 2e-49
Identities = 94/169 (55%), Positives = 110/169 (65%), Gaps = 31/169 (18%)
Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
MN PAPV+V+YK+MRF ITHNPTN TL+ FIED
Sbjct: 1 MNHPAPVKVTYKNMRFPITHNPTNVTLNKFIED--------------------------- 33
Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
WPF DGAPP ++V DWL VK KFCE PG +AV+C+ GLG+APVLVALA +E G
Sbjct: 34 ----WPFGDGAPPSNQIVADWLHFVKIKFCEEPGCYIAVNCIVGLGKAPVLVALASVEGG 89
Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
MK+EDA+QFI QKR GA SKQL YLEKY PK RLRFKD ++H CC+
Sbjct: 90 MKHEDAVQFIGQKRSGAFKSKQLLYLEKYHPKMRLRFKDSNSHINNCCI 138
>gi|18104973 protein tyrosine phosphatase type IVA, member 2
isoform 2 [Homo sapiens]
Length = 82
Score = 105 bits (263), Expect = 1e-23
Identities = 47/63 (74%), Positives = 57/63 (90%)
Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+GI
Sbjct: 1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 60
Query: 64 TVV 66
V+
Sbjct: 61 HVL 63
>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
Length = 461
Score = 58.9 bits (141), Expect = 2e-09
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 32 TFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91
T+I+ K + TT++R+ + YD G D F DG+ P +V+++L +
Sbjct: 210 TYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI---- 265
Query: 92 FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149
CE +AVHC AGLGR L+A +++ M + I ++R R G++ Q +L
Sbjct: 266 -CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 323
>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
Length = 459
Score = 58.9 bits (141), Expect = 2e-09
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 32 TFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91
T+I+ K + TT++R+ + YD G D F DG+ P +V+++L +
Sbjct: 247 TYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI---- 302
Query: 92 FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149
CE +AVHC AGLGR L+A +++ M + I ++R R G++ Q +L
Sbjct: 303 -CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 360
>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
Length = 498
Score = 58.9 bits (141), Expect = 2e-09
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 32 TFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91
T+I+ K + TT++R+ + YD G D F DG+ P +V+++L +
Sbjct: 247 TYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI---- 302
Query: 92 FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149
CE +AVHC AGLGR L+A +++ M + I ++R R G++ Q +L
Sbjct: 303 -CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 360
>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
Length = 383
Score = 55.1 bits (131), Expect = 3e-08
Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 38 KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97
KK+ T VVR+ + Y+ G D F DG+ P +V +L++ CE
Sbjct: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
Query: 98 SCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYLEK 151
+AVHC AGLGR L+A +++ + + I +IR R G+I Q +LE+
Sbjct: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
Length = 594
Score = 55.1 bits (131), Expect = 3e-08
Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 38 KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97
KK+ T VVR+ + Y+ G D F DG+ P +V +L++ CE
Sbjct: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
Query: 98 SCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYLEK 151
+AVHC AGLGR L+A +++ + + I +IR R G+I Q +LE+
Sbjct: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
Length = 623
Score = 55.1 bits (131), Expect = 3e-08
Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 38 KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97
KK+ T VVR+ + Y+ G D F DG+ P +V +L++ CE
Sbjct: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
Query: 98 SCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYLEK 151
+AVHC AGLGR L+A +++ + + I +IR R G+I Q +LE+
Sbjct: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 42.4 bits (98), Expect = 2e-04
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1397 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1455
Query: 126 YE---DAIQFIRQKR--RGAINSKQLTYLEKYR 153
YE D Q ++ R R A+ + Y YR
Sbjct: 1456 YEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1488
Score = 28.9 bits (63), Expect = 2.3
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 22 THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
TH TL +E L Y T + +K + + T WP D G P
Sbjct: 1066 THGLVQVTLLDTVE-LATYCVRTFALYKNGSSEKREVRQFQFTA--WP-DHGVPEHPTPF 1121
Query: 82 EDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKYEDAI 130
+L VK C P + + VHC AG+GR + + + +K+E +
Sbjct: 1122 LAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTV 1169
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 42.4 bits (98), Expect = 2e-04
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1807 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1865
Query: 126 YE---DAIQFIRQKR--RGAINSKQLTYLEKYR 153
YE D Q ++ R R A+ + Y YR
Sbjct: 1866 YEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1898
Score = 28.9 bits (63), Expect = 2.3
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 22 THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
TH TL +E L Y T + +K + + T WP D G P
Sbjct: 1476 THGLVQVTLLDTVE-LATYCVRTFALYKNGSSEKREVRQFQFTA--WP-DHGVPEHPTPF 1531
Query: 82 EDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKYEDAI 130
+L VK C P + + VHC AG+GR + + + +K+E +
Sbjct: 1532 LAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTV 1579
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 42.4 bits (98), Expect = 2e-04
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1794 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1852
Query: 126 YE---DAIQFIRQKR--RGAINSKQLTYLEKYR 153
YE D Q ++ R R A+ + Y YR
Sbjct: 1853 YEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1885
Score = 28.9 bits (63), Expect = 2.3
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 22 THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
TH TL +E L Y T + +K + + T WP D G P
Sbjct: 1463 THGLVQVTLLDTVE-LATYCVRTFALYKNGSSEKREVRQFQFTA--WP-DHGVPEHPTPF 1518
Query: 82 EDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKYEDAI 130
+L VK C P + + VHC AG+GR + + + +K+E +
Sbjct: 1519 LAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTV 1566
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 42.4 bits (98), Expect = 2e-04
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1798 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1856
Query: 126 YE---DAIQFIRQKR--RGAINSKQLTYLEKYR 153
YE D Q ++ R R A+ + Y YR
Sbjct: 1857 YEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1889
Score = 28.9 bits (63), Expect = 2.3
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 22 THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
TH TL +E L Y T + +K + + T WP D G P
Sbjct: 1467 THGLVQVTLLDTVE-LATYCVRTFALYKNGSSEKREVRQFQFTA--WP-DHGVPEHPTPF 1522
Query: 82 EDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKYEDAI 130
+L VK C P + + VHC AG+GR + + + +K+E +
Sbjct: 1523 LAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTV 1570
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 42.4 bits (98), Expect = 2e-04
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1396 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1454
Query: 126 YE---DAIQFIRQKR--RGAINSKQLTYLEKYR 153
YE D Q ++ R R A+ + Y YR
Sbjct: 1455 YEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1487
Score = 28.9 bits (63), Expect = 2.3
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 22 THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
TH TL +E L Y T + +K + + T WP D G P
Sbjct: 1065 THGLVQVTLLDTVE-LATYCVRTFALYKNGSSEKREVRQFQFTA--WP-DHGVPEHPTPF 1120
Query: 82 EDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKYEDAI 130
+L VK C P + + VHC AG+GR + + + +K+E +
Sbjct: 1121 LAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTV 1168
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 42.0 bits (97), Expect = 3e-04
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1400 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1458
Query: 126 YEDAIQFIR 134
YE + +
Sbjct: 1459 YEGVVDIFQ 1467
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 42.0 bits (97), Expect = 3e-04
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1805 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1863
Query: 126 YEDAIQFIR 134
YE + +
Sbjct: 1864 YEGVVDIFQ 1872
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 42.0 bits (97), Expect = 3e-04
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1396 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1454
Query: 126 YEDAIQFIR 134
YE + +
Sbjct: 1455 YEGVVDIFQ 1463
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 42.0 bits (97), Expect = 3e-04
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+
Sbjct: 1843 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 1901
Query: 126 YEDAIQFIR 134
YE + +
Sbjct: 1902 YEGVVDIFQ 1910
>gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
Length = 150
Score = 42.0 bits (97), Expect = 3e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI- 120
G+T+ D PP ++ ++ +V A G V VHC G GR ++A L+
Sbjct: 55 GLTLHRLRIPDFCPPAPDQIDRFVQIVDE--ANARGEAVGVHCALGFGRTGTMLACYLVK 112
Query: 121 ESGMKYEDAIQFIRQKRRGAINS 143
E G+ DAI IR+ R G+I +
Sbjct: 113 ERGLAAGDAIAEIRRLRPGSIET 135
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 41.6 bits (96), Expect = 3e-04
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 65 VVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG- 123
V +PF+D PP ++++ + + E A+HC AG GR V++ L+ G
Sbjct: 85 VAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGK 144
Query: 124 -MKYEDAIQF-----IRQKRRGAINS-KQLTYLEKYRPKQRLRFK 161
+K ++A+ F R K+ I S ++ Y Y K L ++
Sbjct: 145 FLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYR 189
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 41.6 bits (96), Expect = 3e-04
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K + VHC AG+GR V + L+++ M+
Sbjct: 1802 DWP-EQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR 1860
Query: 126 YEDAIQFIR 134
YE + +
Sbjct: 1861 YEGVVDMFQ 1869
Score = 29.3 bits (64), Expect = 1.8
Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
WP D G P + +L VKA G V VHC AG+GR + + + MK+E
Sbjct: 1514 WP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVIDAMLERMKHE 1571
Query: 128 DAI 130
+
Sbjct: 1572 KTV 1574
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 41.6 bits (96), Expect = 3e-04
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
DWP + G P G+ D++ V K K + VHC AG+GR V + L+++ M+
Sbjct: 1793 DWP-EQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR 1851
Query: 126 YEDAIQFIR 134
YE + +
Sbjct: 1852 YEGVVDMFQ 1860
Score = 29.3 bits (64), Expect = 1.8
Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
WP D G P + +L VKA G V VHC AG+GR + + + MK+E
Sbjct: 1505 WP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVIDAMLERMKHE 1562
Query: 128 DAI 130
+
Sbjct: 1563 KTV 1565
>gi|30089952 protein tyrosine phosphatase domain containing 1
protein isoform 1 [Homo sapiens]
Length = 806
Score = 41.2 bits (95), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINS 143
L +VK VA+HC AGLGR VL+A L+ + M + AI F+R KR +I +
Sbjct: 223 LDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQT 282
Query: 144 K-QLTYLEKYRPKQRLRFKDPHTHKTRCC 171
+ QL + ++ +F P + CC
Sbjct: 283 RGQLLCVREF-----TQFLTPLRNIFSCC 306
>gi|30089950 protein tyrosine phosphatase domain containing 1
protein isoform 2 [Homo sapiens]
Length = 754
Score = 41.2 bits (95), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINS 143
L +VK VA+HC AGLGR VL+A L+ + M + AI F+R KR +I +
Sbjct: 171 LDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQT 230
Query: 144 K-QLTYLEKYRPKQRLRFKDPHTHKTRCC 171
+ QL + ++ +F P + CC
Sbjct: 231 RGQLLCVREF-----TQFLTPLRNIFSCC 254
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 37.4 bits (85), Expect = 0.007
Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 94 EAPGSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137
+A CV VHC+AG+ R A + +A + M ++A +F+++KR
Sbjct: 234 KASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKR 278
>gi|5729993 protein tyrosine phosphatase, receptor type, E isoform 1
precursor [Homo sapiens]
Length = 700
Score = 36.2 bits (82), Expect = 0.015
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
WP + G P GK + D ++ V+ + + + VHC AG GR +AL+ I +K E
Sbjct: 595 WP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAE 653
Query: 128 ---DAIQFIRQKR 137
D Q ++ R
Sbjct: 654 GLLDVFQAVKSLR 666
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,350,568
Number of Sequences: 37866
Number of extensions: 309946
Number of successful extensions: 811
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 742
Number of HSP's gapped (non-prelim): 142
length of query: 173
length of database: 18,247,518
effective HSP length: 95
effective length of query: 78
effective length of database: 14,650,248
effective search space: 1142719344
effective search space used: 1142719344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.