BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|145580600 schlafen family member 5 [Homo sapiens] (891 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|145580600 schlafen family member 5 [Homo sapiens] 1806 0.0 gi|56119108 schlafen family member 13 [Homo sapiens] 852 0.0 gi|157388965 schlafen family member 11 [Homo sapiens] 851 0.0 gi|157388963 schlafen family member 11 [Homo sapiens] 851 0.0 gi|157388961 schlafen family member 11 [Homo sapiens] 851 0.0 gi|157388959 schlafen family member 11 [Homo sapiens] 851 0.0 gi|157388957 schlafen family member 11 [Homo sapiens] 851 0.0 gi|193788705 schlafen family member 14 [Homo sapiens] 683 0.0 gi|157388955 schlafen family member 12 [Homo sapiens] 453 e-127 gi|222537745 schlafen family member 12-like [Homo sapiens] 441 e-123 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 32 2.0 gi|115430219 lambda-crystallin [Homo sapiens] 32 2.0 gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 32 2.6 gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 31 4.5 gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 31 4.5 gi|29540551 trophinin isoform 2 [Homo sapiens] 30 7.6 gi|29540541 trophinin isoform 2 [Homo sapiens] 30 7.6 gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens] 30 7.6 gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 30 10.0 gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 30 10.0 >gi|145580600 schlafen family member 5 [Homo sapiens] Length = 891 Score = 1806 bits (4678), Expect = 0.0 Identities = 891/891 (100%), Positives = 891/891 (100%) Query: 1 MSLRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA 60 MSLRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA Sbjct: 1 MSLRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA 60 Query: 61 EIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHR 120 EIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHR Sbjct: 61 EIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHR 120 Query: 121 ERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVSAAALFDRKR 180 ERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVSAAALFDRKR Sbjct: 121 ERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVSAAALFDRKR 180 Query: 181 LQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIG 240 LQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIG Sbjct: 181 LQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIG 240 Query: 241 CEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEK 300 CEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEK Sbjct: 241 CEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEK 300 Query: 301 FCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKP 360 FCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKP Sbjct: 301 FCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKP 360 Query: 361 VCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINTEMRPFSQGILI 420 VCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINTEMRPFSQGILI Sbjct: 361 VCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINTEMRPFSQGILI 420 Query: 421 FSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVN 480 FSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVN Sbjct: 421 FSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVN 480 Query: 481 KGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGF 540 KGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGF Sbjct: 481 KGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGF 540 Query: 541 KSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNVFH 600 KSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNVFH Sbjct: 541 KSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNVFH 600 Query: 601 CEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGD 660 CEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGD Sbjct: 601 CEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGD 660 Query: 661 WYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIAN 720 WYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIAN Sbjct: 661 WYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIAN 720 Query: 721 YLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLNLEEILIYVANKCRFL 780 YLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLNLEEILIYVANKCRFL Sbjct: 721 YLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLNLEEILIYVANKCRFL 780 Query: 781 LRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHI 840 LRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHI Sbjct: 781 LRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHI 840 Query: 841 VLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLYILKASV 891 VLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLYILKASV Sbjct: 841 VLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLYILKASV 891 >gi|56119108 schlafen family member 13 [Homo sapiens] Length = 897 Score = 852 bits (2200), Expect = 0.0 Identities = 455/902 (50%), Positives = 609/902 (67%), Gaps = 34/902 (3%) Query: 5 IDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIEN 64 + V ++P+ V+D G+VTLG + R+++ R+++ ++RA CALLNSGGG+I+ E+ N Sbjct: 8 LGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGVIQMEMAN 67 Query: 65 KGYNYERHGVGLDVP-------PIFRSHLDKMQKENHFLIFVKSWNTEAGVP-------L 110 + G+ L+ P ++ + Q F IFVKSW+ + + + Sbjct: 68 RDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSFNSRI 127 Query: 111 ATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINV 170 +L S+LY R TS M+S++A FLK + + + N+ N P + Y+ NI+ Sbjct: 128 CSLSSSLYCRSGTSVLHMNSRQAFDFLKTK-ERQSKYNLINEGSPPSKIMKAVYQ-NISE 185 Query: 171 SAAA--LFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227 S A +F ++Y E L+ PES +EF FST + V++ +P+ +SAFANTEGGY+ Sbjct: 186 SNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGGYL 245 Query: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287 F GV D++ +V+GC KE++D SL+ I I KLP+ HFC+ +P ++Y +EV Sbjct: 246 FIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVEVFCGK 305 Query: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSR--CPEM 345 L GY+C IKV+ FCC VF++ P SW V++ +R L T EW MM+ADP+ Sbjct: 306 ELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPDFAEAF 365 Query: 346 VLQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRD 405 QLSLS + +PV K E + Q+ FPV + TPESL+KEL QH+GL++ Sbjct: 366 ESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQHEGLKE 425 Query: 406 LINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKG 465 LI+ +MRPFSQGI+I S+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA + Sbjct: 426 LIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQD 485 Query: 466 YSMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQ 524 Y A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ Q Sbjct: 486 YCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQ 545 Query: 525 HMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGK 584 HMEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGK Sbjct: 546 HMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGK 605 Query: 585 TILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQ 644 TI+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TR+TF++ FEHIQ Sbjct: 606 TIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRETFLREKFEHIQ 663 Query: 645 HIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYP 704 HI+ID+AQNFRTEDGDWY KAK ITQ +D PGVLWIFLDYFQT HL SGLPP S QYP Sbjct: 664 HIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHSGLPPLSAQYP 723 Query: 705 REEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDL 764 REE+ RVVRNA IA Y+QQ MQ +NPP N+P G L +L E KW GVPGN +II++ Sbjct: 724 REELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGVPGNTKIIKNF 783 Query: 765 NLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESD 824 LE+I+ YVA+ CR GYSPKD+AVL + +EVE+Y+ +LL AMRK+ Sbjct: 784 TLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK---------- 833 Query: 825 LLLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHL 884 +++Q+ DA D+L HIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HL Sbjct: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893 Query: 885 YI 886 YI Sbjct: 894 YI 895 >gi|157388965 schlafen family member 11 [Homo sapiens] Length = 901 Score = 851 bits (2198), Expect = 0.0 Identities = 463/901 (51%), Positives = 604/901 (67%), Gaps = 36/901 (3%) Query: 7 VDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA--EIEN 64 V+ ++P+ V++ G+VTLG + R+++ R+++ E ++RA CALLNSGGG+I+ ++E+ Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEH 69 Query: 65 K---GYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNT-------EAGVPLATLC 114 G + E+ L ++ + Q+ F IFVKSW++ L +L Sbjct: 70 PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLS 129 Query: 115 SNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS--- 171 S+LY R TS MDS+EA FLK + + + + +G Q N + + Sbjct: 130 SSLYRRSETSVRSMDSREAFCFLKTKRKPKI---LEEGPFHKIHKGVYQELPNSDPADPN 186 Query: 172 ---AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227 A +F + L+Y E L PES VEF FST VK +P+ V AFANT GGY+ Sbjct: 187 SDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYL 246 Query: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287 F GV D++ +V+GC KE +D SLR I+ I KLP HFC + I + L + V +G Sbjct: 247 FIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRG 306 Query: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPE-MV 346 L GY C I+V FCCAVF++ P+SW V+D V L T +W M + DPDL + E Sbjct: 307 ELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFE 366 Query: 347 LQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDL 406 QLSLSS P S+PV K E KE Q+ F V + YTPESL+++L S+H+GL +L Sbjct: 367 CQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEEL 426 Query: 407 INTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGY 466 IN +M+PF +GILIFS+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA + Y Sbjct: 427 INKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDY 486 Query: 467 SMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQH 525 A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ QH Sbjct: 487 CTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQH 546 Query: 526 MEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKT 585 MEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGKT Sbjct: 547 MEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKT 606 Query: 586 ILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQH 645 I+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TRKTF++ NFEHIQH Sbjct: 607 IMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRKTFLRENFEHIQH 664 Query: 646 IIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPR 705 I+ID+AQNFRTEDGDWYGKAK IT+ A+ GPG+LWIFLDYFQT HL CSGLPP SDQYPR Sbjct: 665 IVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPR 724 Query: 706 EEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLN 765 EE+ R+VRNA PIA YLQ+ MQ R NP N+P G L + E +W+QGV G L I + L Sbjct: 725 EELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLT 784 Query: 766 LEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDL 825 +E+I+ VA+ CR GYSPKD+AVL + A EVE YK LL AMRK++ Sbjct: 785 VEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKR---------- 834 Query: 826 LLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLY 885 ++Q+ DA D+L DHIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HLY Sbjct: 835 VVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLY 894 Query: 886 I 886 I Sbjct: 895 I 895 >gi|157388963 schlafen family member 11 [Homo sapiens] Length = 901 Score = 851 bits (2198), Expect = 0.0 Identities = 463/901 (51%), Positives = 604/901 (67%), Gaps = 36/901 (3%) Query: 7 VDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA--EIEN 64 V+ ++P+ V++ G+VTLG + R+++ R+++ E ++RA CALLNSGGG+I+ ++E+ Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEH 69 Query: 65 K---GYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNT-------EAGVPLATLC 114 G + E+ L ++ + Q+ F IFVKSW++ L +L Sbjct: 70 PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLS 129 Query: 115 SNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS--- 171 S+LY R TS MDS+EA FLK + + + + +G Q N + + Sbjct: 130 SSLYRRSETSVRSMDSREAFCFLKTKRKPKI---LEEGPFHKIHKGVYQELPNSDPADPN 186 Query: 172 ---AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227 A +F + L+Y E L PES VEF FST VK +P+ V AFANT GGY+ Sbjct: 187 SDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYL 246 Query: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287 F GV D++ +V+GC KE +D SLR I+ I KLP HFC + I + L + V +G Sbjct: 247 FIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRG 306 Query: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPE-MV 346 L GY C I+V FCCAVF++ P+SW V+D V L T +W M + DPDL + E Sbjct: 307 ELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFE 366 Query: 347 LQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDL 406 QLSLSS P S+PV K E KE Q+ F V + YTPESL+++L S+H+GL +L Sbjct: 367 CQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEEL 426 Query: 407 INTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGY 466 IN +M+PF +GILIFS+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA + Y Sbjct: 427 INKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDY 486 Query: 467 SMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQH 525 A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ QH Sbjct: 487 CTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQH 546 Query: 526 MEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKT 585 MEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGKT Sbjct: 547 MEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKT 606 Query: 586 ILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQH 645 I+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TRKTF++ NFEHIQH Sbjct: 607 IMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRKTFLRENFEHIQH 664 Query: 646 IIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPR 705 I+ID+AQNFRTEDGDWYGKAK IT+ A+ GPG+LWIFLDYFQT HL CSGLPP SDQYPR Sbjct: 665 IVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPR 724 Query: 706 EEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLN 765 EE+ R+VRNA PIA YLQ+ MQ R NP N+P G L + E +W+QGV G L I + L Sbjct: 725 EELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLT 784 Query: 766 LEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDL 825 +E+I+ VA+ CR GYSPKD+AVL + A EVE YK LL AMRK++ Sbjct: 785 VEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKR---------- 834 Query: 826 LLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLY 885 ++Q+ DA D+L DHIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HLY Sbjct: 835 VVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLY 894 Query: 886 I 886 I Sbjct: 895 I 895 >gi|157388961 schlafen family member 11 [Homo sapiens] Length = 901 Score = 851 bits (2198), Expect = 0.0 Identities = 463/901 (51%), Positives = 604/901 (67%), Gaps = 36/901 (3%) Query: 7 VDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA--EIEN 64 V+ ++P+ V++ G+VTLG + R+++ R+++ E ++RA CALLNSGGG+I+ ++E+ Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEH 69 Query: 65 K---GYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNT-------EAGVPLATLC 114 G + E+ L ++ + Q+ F IFVKSW++ L +L Sbjct: 70 PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLS 129 Query: 115 SNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS--- 171 S+LY R TS MDS+EA FLK + + + + +G Q N + + Sbjct: 130 SSLYRRSETSVRSMDSREAFCFLKTKRKPKI---LEEGPFHKIHKGVYQELPNSDPADPN 186 Query: 172 ---AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227 A +F + L+Y E L PES VEF FST VK +P+ V AFANT GGY+ Sbjct: 187 SDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYL 246 Query: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287 F GV D++ +V+GC KE +D SLR I+ I KLP HFC + I + L + V +G Sbjct: 247 FIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRG 306 Query: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPE-MV 346 L GY C I+V FCCAVF++ P+SW V+D V L T +W M + DPDL + E Sbjct: 307 ELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFE 366 Query: 347 LQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDL 406 QLSLSS P S+PV K E KE Q+ F V + YTPESL+++L S+H+GL +L Sbjct: 367 CQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEEL 426 Query: 407 INTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGY 466 IN +M+PF +GILIFS+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA + Y Sbjct: 427 INKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDY 486 Query: 467 SMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQH 525 A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ QH Sbjct: 487 CTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQH 546 Query: 526 MEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKT 585 MEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGKT Sbjct: 547 MEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKT 606 Query: 586 ILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQH 645 I+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TRKTF++ NFEHIQH Sbjct: 607 IMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRKTFLRENFEHIQH 664 Query: 646 IIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPR 705 I+ID+AQNFRTEDGDWYGKAK IT+ A+ GPG+LWIFLDYFQT HL CSGLPP SDQYPR Sbjct: 665 IVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPR 724 Query: 706 EEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLN 765 EE+ R+VRNA PIA YLQ+ MQ R NP N+P G L + E +W+QGV G L I + L Sbjct: 725 EELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLT 784 Query: 766 LEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDL 825 +E+I+ VA+ CR GYSPKD+AVL + A EVE YK LL AMRK++ Sbjct: 785 VEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKR---------- 834 Query: 826 LLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLY 885 ++Q+ DA D+L DHIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HLY Sbjct: 835 VVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLY 894 Query: 886 I 886 I Sbjct: 895 I 895 >gi|157388959 schlafen family member 11 [Homo sapiens] Length = 901 Score = 851 bits (2198), Expect = 0.0 Identities = 463/901 (51%), Positives = 604/901 (67%), Gaps = 36/901 (3%) Query: 7 VDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA--EIEN 64 V+ ++P+ V++ G+VTLG + R+++ R+++ E ++RA CALLNSGGG+I+ ++E+ Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEH 69 Query: 65 K---GYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNT-------EAGVPLATLC 114 G + E+ L ++ + Q+ F IFVKSW++ L +L Sbjct: 70 PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLS 129 Query: 115 SNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS--- 171 S+LY R TS MDS+EA FLK + + + + +G Q N + + Sbjct: 130 SSLYRRSETSVRSMDSREAFCFLKTKRKPKI---LEEGPFHKIHKGVYQELPNSDPADPN 186 Query: 172 ---AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227 A +F + L+Y E L PES VEF FST VK +P+ V AFANT GGY+ Sbjct: 187 SDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYL 246 Query: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287 F GV D++ +V+GC KE +D SLR I+ I KLP HFC + I + L + V +G Sbjct: 247 FIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRG 306 Query: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPE-MV 346 L GY C I+V FCCAVF++ P+SW V+D V L T +W M + DPDL + E Sbjct: 307 ELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFE 366 Query: 347 LQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDL 406 QLSLSS P S+PV K E KE Q+ F V + YTPESL+++L S+H+GL +L Sbjct: 367 CQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEEL 426 Query: 407 INTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGY 466 IN +M+PF +GILIFS+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA + Y Sbjct: 427 INKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDY 486 Query: 467 SMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQH 525 A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ QH Sbjct: 487 CTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQH 546 Query: 526 MEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKT 585 MEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGKT Sbjct: 547 MEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKT 606 Query: 586 ILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQH 645 I+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TRKTF++ NFEHIQH Sbjct: 607 IMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRKTFLRENFEHIQH 664 Query: 646 IIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPR 705 I+ID+AQNFRTEDGDWYGKAK IT+ A+ GPG+LWIFLDYFQT HL CSGLPP SDQYPR Sbjct: 665 IVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPR 724 Query: 706 EEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLN 765 EE+ R+VRNA PIA YLQ+ MQ R NP N+P G L + E +W+QGV G L I + L Sbjct: 725 EELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLT 784 Query: 766 LEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDL 825 +E+I+ VA+ CR GYSPKD+AVL + A EVE YK LL AMRK++ Sbjct: 785 VEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKR---------- 834 Query: 826 LLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLY 885 ++Q+ DA D+L DHIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HLY Sbjct: 835 VVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLY 894 Query: 886 I 886 I Sbjct: 895 I 895 >gi|157388957 schlafen family member 11 [Homo sapiens] Length = 901 Score = 851 bits (2198), Expect = 0.0 Identities = 463/901 (51%), Positives = 604/901 (67%), Gaps = 36/901 (3%) Query: 7 VDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKA--EIEN 64 V+ ++P+ V++ G+VTLG + R+++ R+++ E ++RA CALLNSGGG+I+ ++E+ Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEH 69 Query: 65 K---GYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNT-------EAGVPLATLC 114 G + E+ L ++ + Q+ F IFVKSW++ L +L Sbjct: 70 PVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLS 129 Query: 115 SNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS--- 171 S+LY R TS MDS+EA FLK + + + + +G Q N + + Sbjct: 130 SSLYRRSETSVRSMDSREAFCFLKTKRKPKI---LEEGPFHKIHKGVYQELPNSDPADPN 186 Query: 172 ---AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227 A +F + L+Y E L PES VEF FST VK +P+ V AFANT GGY+ Sbjct: 187 SDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYL 246 Query: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287 F GV D++ +V+GC KE +D SLR I+ I KLP HFC + I + L + V +G Sbjct: 247 FIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRG 306 Query: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPE-MV 346 L GY C I+V FCCAVF++ P+SW V+D V L T +W M + DPDL + E Sbjct: 307 ELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFE 366 Query: 347 LQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDL 406 QLSLSS P S+PV K E KE Q+ F V + YTPESL+++L S+H+GL +L Sbjct: 367 CQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEEL 426 Query: 407 INTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGY 466 IN +M+PF +GILIFS+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA + Y Sbjct: 427 INKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDY 486 Query: 467 SMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQH 525 A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ QH Sbjct: 487 CTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQH 546 Query: 526 MEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKT 585 MEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGKT Sbjct: 547 MEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKT 606 Query: 586 ILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQH 645 I+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TRKTF++ NFEHIQH Sbjct: 607 IMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRKTFLRENFEHIQH 664 Query: 646 IIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPR 705 I+ID+AQNFRTEDGDWYGKAK IT+ A+ GPG+LWIFLDYFQT HL CSGLPP SDQYPR Sbjct: 665 IVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPR 724 Query: 706 EEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLN 765 EE+ R+VRNA PIA YLQ+ MQ R NP N+P G L + E +W+QGV G L I + L Sbjct: 725 EELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLT 784 Query: 766 LEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDL 825 +E+I+ VA+ CR GYSPKD+AVL + A EVE YK LL AMRK++ Sbjct: 785 VEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKR---------- 834 Query: 826 LLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLY 885 ++Q+ DA D+L DHIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HLY Sbjct: 835 VVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLY 894 Query: 886 I 886 I Sbjct: 895 I 895 >gi|193788705 schlafen family member 14 [Homo sapiens] Length = 912 Score = 683 bits (1762), Expect = 0.0 Identities = 393/920 (42%), Positives = 559/920 (60%), Gaps = 51/920 (5%) Query: 2 SLRIDVDTNFPECVVDAGKVTLGTQQRQEM-DPRLREKQNEIILRAVCALLNSGGGIIKA 60 SL+ D + +PE +VD G+V G + R++M + L+ +N I+RA+CALLNSGGG+IKA Sbjct: 3 SLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKA 62 Query: 61 EIENKGYNYERHGVGLDVPPIFRS--------HLDKMQKENHFLIFVKSWNTEA-GVPL- 110 EI++K Y+Y+ HG+G D+ F+ +LD MQ+ ++ LIFVKSW+ + +PL Sbjct: 63 EIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLR 122 Query: 111 -ATLCSNLYHRERTSTDVMDSQEALAFLK---CRTQTPTNINVSNSLGPQAAQGSVQYEG 166 +L SNLY R+ TS + + AL L+ R Q V Q +Q E Sbjct: 123 ICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRP-RVKKLHPQQVLNRCIQEEE 181 Query: 167 NINVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGG 225 ++ + A+ F + +L Y EKLN ESTHVEF F+T V +K+ LP VSAFANT+GG Sbjct: 182 DMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGG 241 Query: 226 YVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHD 285 YV GV D++ +V+GC+ EK++ L+ I+ CI+KLP HFC ++P++ + L V+ Sbjct: 242 YVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQ 301 Query: 286 KGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMME---ADPDLSRC 342 K L GYVC I+VE FCC VFA+ P SW +KDN V +L +W M++ A P L Sbjct: 302 KDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTD 361 Query: 343 PEMVLQLSLSSATPR-SKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHK 401 L S SSA P+ +HK E L Q+ FPV + V + PESL K+LFS HK Sbjct: 362 YNSCLISSASSARKSPGYPIKVHKFKEAL---QRHLFPVTQEEVQFKPESLCKKLFSDHK 418 Query: 402 GLRDLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIF--SKW 459 L L+ T + P SQGI+IFS+SWA D+G +++Q V+CDALLI+ N+ +LYTI W Sbjct: 419 ELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNW 478 Query: 460 DAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQIYPESYN 519 G + Y+ A+ LKQKL GGYTG++CI P + L+S QS YP SY Sbjct: 479 PGGLE-YARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSS---TQSRPGEIPLRYPRSYR 534 Query: 520 FMTPQHMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGL 579 + ME LLQ+LV+V L +S LS+++G E NLL +Q +LLS++L+KTRELF++ Sbjct: 535 LADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCF 594 Query: 580 PGSGKTILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNN 639 PG KT LA++IMEKI+++FHC+P ILY+CE+ LK V +++ CQ VTRKTFM+ Sbjct: 595 PGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFV--TQQTTCQAVTRKTFMQGE 652 Query: 640 FEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARDGP-------GVLWIFLDYFQTYHLS 692 F I+HI++D+ +NF ++ G+WY KAK IT G G+LW+FLD FQ +H Sbjct: 653 FLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHAD 712 Query: 693 CSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKW-- 750 +GLPPPS Q+PR+ I + A IA +++ M+ ++NPP N+ P +L + E + Sbjct: 713 VNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEE 772 Query: 751 ---AQGVPGNLEIIEDLNLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRL 807 AQ +PG E +L E+I YVA KC L + GY PKDIA+L + + +Y+ L Sbjct: 773 ATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLAL 832 Query: 808 LTAMRKRKLSQLHEESDLLLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPA 867 L AM +L + H S+++ A+ V HIVLDS+ +FSGLER +VFG++P Sbjct: 833 LKAM---ELIETHRPSEVV--FSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSE 887 Query: 868 GAYNLLLCLASRAKRHLYIL 887 + LC ASRA +HLY+L Sbjct: 888 EFHK--LCFASRAIKHLYLL 905 >gi|157388955 schlafen family member 12 [Homo sapiens] Length = 578 Score = 453 bits (1166), Expect = e-127 Identities = 251/546 (45%), Positives = 351/546 (64%), Gaps = 21/546 (3%) Query: 1 MSLRIDVDTNFPECVVDAGKVTLGTQQRQEM-DPRLREKQNEIILRAVCALLNSGGGIIK 59 M++ +D++TN+ E V+D G+VTLG R++M D +LR+KQNE + RA+CALLNSGGG+IK Sbjct: 1 MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK 60 Query: 60 AEIENKGYNYERHGVGLDVPPIFRS-------HLDKMQKENHFLIFVKSWNTE-AGVPLA 111 AEIEN+ Y+Y + G+GLD+ F + +LD MQ N+FLIFVKSW+ +G+ + Sbjct: 61 AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT 120 Query: 112 TLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS 171 TL SNLY R+ TS VM++ AL FLK +T + + L + +Q E N+ Sbjct: 121 TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL 180 Query: 172 AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYVFFG 230 A FDR L EKL ESTHVE FST+ + +K+ LP+ VSAFANT+GGY+F G Sbjct: 181 AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG 240 Query: 231 VHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALR 290 ++++ ++IG + E DL L I+ I+K+PVHHFC ++ +I Y FL V+DKG+L Sbjct: 241 LNEDK-EIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLC 299 Query: 291 GYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRC-PEMVLQL 349 GYVCA++VE+FCCAVFAK P SW VKDNRV QL +EW +M+EA+P S E++ Q+ Sbjct: 300 GYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQI 359 Query: 350 SLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINT 409 + S P S P+ ++Q+ + P S R+ YTPE+L ++LF QH+GL+ LI Sbjct: 360 NTSLPAPHSWPLLEW-------QRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICE 412 Query: 410 EMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMI 469 EM +G LIFS+SW+VDLGLQE V+CDALLISQ++ P+LYT D KGYS Sbjct: 413 EMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQ 472 Query: 470 VAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQ-IYPESYNFMTPQH-ME 527 A +LKQKL GGYT ++C+ + L+ + Y Q IYPESY F ++ ++ Sbjct: 473 TALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLK 532 Query: 528 ALLQSL 533 AL ++L Sbjct: 533 ALFKAL 538 >gi|222537745 schlafen family member 12-like [Homo sapiens] Length = 617 Score = 441 bits (1134), Expect = e-123 Identities = 254/549 (46%), Positives = 346/549 (63%), Gaps = 19/549 (3%) Query: 1 MSLRIDVDTNFPECVVDAGKVTLGTQQRQEM-DPRLREKQNEIILRAVCALLNSGGGIIK 59 M++ ID+DTN+ E V++ G+VTLG R++M D +LR++QNE + RAVCALLNSGGG+IK Sbjct: 48 MNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIK 107 Query: 60 AEIENKGYNYERHGVGLDVP-------PIFRSHLDKMQKENHFLIFVKSWNTEAGVP-LA 111 AE+ENKGY+Y++ G+GLD+ P + LD MQ N+F IFVKSW+ E P +A Sbjct: 108 AEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIA 167 Query: 112 TLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS 171 TL S+LY R+ TS VM++ AL FLK +T + + A VQ E N+ Sbjct: 168 TLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEAL 227 Query: 172 AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYVFFG 230 AA F+R L Y EKL ESTHVE FST+ + + + LP+ VSAFANT+GGY+F G Sbjct: 228 AADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVG 287 Query: 231 VHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALR 290 ++++ +VIG + EK LT L I KLPVHHFC ++ I Y+ FL V+DKG L Sbjct: 288 LNEDK-EVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLC 346 Query: 291 GYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLS 350 GYV A++VE+FCCAVFAK P SW VKDNRV+QL +EW +M++++P C E+ S Sbjct: 347 GYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP---VCEELPSPAS 403 Query: 351 LSSATPRSKPVCIHKNSECLKEQQKRY-FPVFSDRVVYTPESLYKELFSQHKGLRDLINT 409 SS +S P+ + N K Q RY P S+++ P++ + LFSQH+GL+ LI Sbjct: 404 TSSPVSQSYPLREYIN---FKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICE 460 Query: 410 EMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMI 469 EM ++G LIFS+SW++DLGLQE V+CDALLISQ+ P+LYT D K YS Sbjct: 461 EMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQ 520 Query: 470 VAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQ-IYPESYNFMTPQHMEA 528 A +LKQKL GGYT ++C+ + L+ + K Y Q IYPESY + T Q M+ Sbjct: 521 TAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKD 580 Query: 529 LLQSLVIVL 537 L ++L +L Sbjct: 581 LEKALSNIL 589 Score = 50.4 bits (119), Expect = 7e-06 Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 12/53 (22%) Query: 587 LALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNN 639 +A++IMEKIRNVFHCE ILYICE+Q L+ + RK F++ N Sbjct: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI------------RKEFLRGN 41 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 32.3 bits (72), Expect = 2.0 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 9/69 (13%) Query: 776 KCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRK------LSQLHEESDLLLQI 829 K + LL++ + K++A T E +K KD L + KRK ++ L E++DL LQ+ Sbjct: 838 KIKPLLKSAETEKEMA---TMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQV 894 Query: 830 GDASDVLTD 838 +D L D Sbjct: 895 QSEADSLAD 903 >gi|115430219 lambda-crystallin [Homo sapiens] Length = 319 Score = 32.3 bits (72), Expect = 2.0 Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 674 DGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNP 733 +G G+ + F+ +T HL+ G+ D+Y E I V++ GPI + + ++ Q+ Sbjct: 226 EGLGMRYAFIGPLETMHLNAEGMLSYCDRY-SEGIKHVLQTFGPIPEFSRATAEKVNQDM 284 Query: 734 PPNLP 738 +P Sbjct: 285 CMKVP 289 >gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] Length = 980 Score = 32.0 bits (71), Expect = 2.6 Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 3/45 (6%) Query: 546 EELGSEVLNL--LTNKQYELLSKNLRKTRELFVHGLPGSGKTILA 588 +E+ E+L L + ELLS LR++ L +HG PG+GKT+LA Sbjct: 711 QEVKKEILETIQLPLEHPELLSLGLRRSG-LLLHGPPGTGKTLLA 754 >gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] Length = 562 Score = 31.2 bits (69), Expect = 4.5 Identities = 16/49 (32%), Positives = 27/49 (55%) Query: 546 EELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEK 594 E+ G + LN+ ++LRK + +F+ G PGSGK +++EK Sbjct: 351 EDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 399 >gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] Length = 536 Score = 31.2 bits (69), Expect = 4.5 Identities = 16/49 (32%), Positives = 27/49 (55%) Query: 546 EELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEK 594 E+ G + LN+ ++LRK + +F+ G PGSGK +++EK Sbjct: 325 EDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373 >gi|29540551 trophinin isoform 2 [Homo sapiens] Length = 706 Score = 30.4 bits (67), Expect = 7.6 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 6/132 (4%) Query: 251 LRASIDGCIKKLPVHHFCTQRP-EIKYVLNFL--EVHDKGALRGY--VCAIKVEKFCCAV 305 +R S+ G ++KL F Q+ E K V N E LR Y +KV KF C V Sbjct: 568 VRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRV 627 Query: 306 FAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKPVCIHK 365 K P W V+ ++ + + EA+ + LQ+ L + + S +H Sbjct: 628 QKKDPKDWAVQYREAVEMEVQAAAVAVAEAEA-RAEIYSPCLQIPLINCSSPSHGAKVHP 686 Query: 366 NSECLKEQQKRY 377 + C Q Y Sbjct: 687 WNLCPHSSQGSY 698 >gi|29540541 trophinin isoform 2 [Homo sapiens] Length = 706 Score = 30.4 bits (67), Expect = 7.6 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 6/132 (4%) Query: 251 LRASIDGCIKKLPVHHFCTQRP-EIKYVLNFL--EVHDKGALRGY--VCAIKVEKFCCAV 305 +R S+ G ++KL F Q+ E K V N E LR Y +KV KF C V Sbjct: 568 VRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRV 627 Query: 306 FAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKPVCIHK 365 K P W V+ ++ + + EA+ + LQ+ L + + S +H Sbjct: 628 QKKDPKDWAVQYREAVEMEVQAAAVAVAEAEA-RAEIYSPCLQIPLINCSSPSHGAKVHP 686 Query: 366 NSECLKEQQKRY 377 + C Q Y Sbjct: 687 WNLCPHSSQGSY 698 >gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens] Length = 1048 Score = 30.4 bits (67), Expect = 7.6 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 12/49 (24%) Query: 569 RKTRELFVHGLPGSGKTILALRIM-EKIRN-----------VFHCEPAN 605 R+ + + + G PG GKTILA ++M E RN FHC+ N Sbjct: 201 RQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVN 249 >gi|154354983 regulating synaptic membrane exocytosis 2 isoform a [Homo sapiens] Length = 1349 Score = 30.0 bits (66), Expect = 10.0 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 626 ICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDY 685 I PV R+ F + E I + D R E+ ++ G+ +TA W L Sbjct: 815 IYSPVHRREFRERMLE----ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKL-- 868 Query: 686 FQTYHLSCSGLPPPSDQYPREEIN 709 QT+ +S LP PS PR +++ Sbjct: 869 -QTHDVSSLPLPHPSPYMPRRQLH 891 >gi|154354981 regulating synaptic membrane exocytosis 2 isoform b [Homo sapiens] Length = 1163 Score = 30.0 bits (66), Expect = 10.0 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 626 ICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDY 685 I PV R+ F + E I + D R E+ ++ G+ +TA W L Sbjct: 607 IYSPVHRREFRERMLE----ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKL-- 660 Query: 686 FQTYHLSCSGLPPPSDQYPREEIN 709 QT+ +S LP PS PR +++ Sbjct: 661 -QTHDVSSLPLPHPSPYMPRRQLH 683 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,820,021 Number of Sequences: 37866 Number of extensions: 1669863 Number of successful extensions: 3644 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 3549 Number of HSP's gapped (non-prelim): 30 length of query: 891 length of database: 18,247,518 effective HSP length: 111 effective length of query: 780 effective length of database: 14,044,392 effective search space: 10954625760 effective search space used: 10954625760 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.