Guide to the Human Genome
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Search of human proteins with 145309315

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145309315 G protein-coupled receptor 62 [Homo sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145309315 G protein-coupled receptor 62 [Homo sapiens]             733   0.0  
gi|57165371 G protein-coupled receptor 61 [Homo sapiens]              155   4e-38
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    89   8e-18
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]                76   4e-14
gi|62865887 G protein-coupled receptor 54 [Homo sapiens]               72   1e-12
gi|28875799 cholecystokinin B receptor [Homo sapiens]                  67   3e-11
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 64   2e-10
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]            64   3e-10
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]             64   3e-10
gi|36951034 G protein-coupled receptor 78 [Homo sapiens]               64   3e-10
gi|23463303 purinergic receptor P2Y11 [Homo sapiens]                   62   8e-10
gi|99028871 PPAN-P2RY11 protein [Homo sapiens]                         62   8e-10
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                 60   2e-09
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]     59   5e-09
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]     59   5e-09
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     59   5e-09
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]     59   5e-09
gi|32261309 G protein-coupled receptor 135 [Homo sapiens]              57   2e-08
gi|4758474 G protein-coupled receptor 10 [Homo sapiens]                56   4e-08
gi|9506745 urotensin 2 receptor [Homo sapiens]                         54   2e-07
gi|149944554 somatostatin receptor 4 [Homo sapiens]                    53   4e-07
gi|4557861 somatostatin receptor 3 [Homo sapiens]                      52   6e-07
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap...    52   8e-07
gi|5174595 melatonin receptor 1B [Homo sapiens]                        52   1e-06
gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo s...    52   1e-06
gi|32483397 dopamine receptor D4 [Homo sapiens]                        51   1e-06
gi|4503907 galanin receptor 3 [Homo sapiens]                           51   1e-06
gi|4503905 galanin receptor 2 [Homo sapiens]                           49   5e-06
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa...    49   5e-06
gi|28173558 trace amine associated receptor 6 [Homo sapiens]           48   1e-05

>gi|145309315 G protein-coupled receptor 62 [Homo sapiens]
          Length = 368

 Score =  733 bits (1892), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLL 60
           MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLL
Sbjct: 1   MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLL 60

Query: 61  AAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHP 120
           AAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHP
Sbjct: 61  AAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHP 120

Query: 121 LRPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALLA 180
           LRPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALLA
Sbjct: 121 LRPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALLA 180

Query: 181 FALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAA 240
           FALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAA
Sbjct: 181 FALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAA 240

Query: 241 LAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLA 300
           LAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLA
Sbjct: 241 LAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLA 300

Query: 301 LGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQ 360
           LGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQ
Sbjct: 301 LGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQ 360

Query: 361 GPPESSLS 368
           GPPESSLS
Sbjct: 361 GPPESSLS 368


>gi|57165371 G protein-coupled receptor 61 [Homo sapiens]
          Length = 451

 Score =  155 bits (393), Expect = 4e-38
 Identities = 123/377 (32%), Positives = 180/377 (47%), Gaps = 38/377 (10%)

Query: 15  SLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLLAAASIMPLGLLAAP 74
           S+ L    ++++ A+ GN A++ V+ +TP LR  +++ HLC+VDLLAA ++MPL +L++ 
Sbjct: 43  SVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSS 102

Query: 75  PPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGSRPPPVL--- 131
                    G   CR   FLS   +    L V+A+ + RY  +VHP+R   R    L   
Sbjct: 103 AL-FDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVAS 161

Query: 132 VLTAVWAAAGLLGALSLLGT---PPAPPPAPARCSVL---AGGLGPFRPLWALLAFALPA 185
           VL  VW  A  + ++ +LG        P  P  CS+    +     F  ++A+L F LP 
Sbjct: 162 VLVGVWVKALAMASVPVLGRVSWEEGAPSVPPGCSLQWSHSAYCQLFVVVFAVLYFLLPL 221

Query: 186 LLLLGAYGGIFVVARRAALRP---PRPARGSRLHSDSLDSRLSIL-----PPLRPR--LP 235
           LL+L  Y  +F VAR AA++    P      R  S+SL SR +++     P   P     
Sbjct: 222 LLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFG 281

Query: 236 GGKAALAPALAVGQFAACWLPY-----GCACLAPAARAAEAEAAVTWVAYSAFAAHPFLY 290
           GGKAA+      GQF  CWLPY       A  A      + E+ VTW+ Y  F ++PF Y
Sbjct: 282 GGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISTGQVESVVTWIGYFCFTSNPFFY 341

Query: 291 GLLQRPVRLALGRLSRRAL----PGP---VRACTPQAWHPRALLQCLQR---PPEGPAVG 340
           G L R +R   G LS++ +    P P   +R  + +       LQ LQ    P E     
Sbjct: 342 GCLNRQIR---GELSKQFVCFFKPAPEEELRLPSREGSIEENFLQFLQGTGCPSESWVSR 398

Query: 341 PSEAPEQTPELAGGRSP 357
           P  +P+Q P     R P
Sbjct: 399 PLPSPKQEPPAVDFRIP 415


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 99/344 (28%), Positives = 135/344 (39%), Gaps = 61/344 (17%)

Query: 2   ANST---GLNASEVAGSLGLILAAVVEVGALLG--NGALLVVVLRTPGLRDA--LYLAHL 54
           ANST   G       G  G + AA+  V AL    N  L+ ++   P LR+    +L  L
Sbjct: 9   ANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSL 68

Query: 55  CVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARY 114
              DL+    +MP  +L A     GR  L    C            A  L +  + L RY
Sbjct: 69  FTSDLMVGLVVMPPAMLNAL---YGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRY 125

Query: 115 RLIVHPLRPGSRPPPVLVLTAV---WAAAGLLGALSLL----GTPPAPPPAPARCSVLAG 167
            LI+ PLR   R  P+  L  V   W+ A L   L LL        A PP P +C +LA 
Sbjct: 126 LLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLAS 185

Query: 168 GLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAAL--------------------RPP 207
              PF  + + L F LP+  +   Y  I + AR+ A+                    R P
Sbjct: 186 L--PFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTP 243

Query: 208 RPARGSRLHSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYG--------C 259
           RP        +S DSR       R  L   KA+L   + +G F   WLP+         C
Sbjct: 244 RPG------VESADSRRLATKHSRKAL---KASLTLGILLGMFFVTWLPFFVANIVQAVC 294

Query: 260 ACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLALGR 303
            C++P          +TW+ Y     +P +Y L  R  + ALGR
Sbjct: 295 DCISPGLFDV-----LTWLGYCNSTMNPIIYPLFMRDFKRALGR 333


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 99/363 (27%), Positives = 146/363 (40%), Gaps = 56/363 (15%)

Query: 2   ANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLLA 61
           AN++GL       +L   L A+  +  + GN  ++V +  TP L+    + ++ V  L A
Sbjct: 25  ANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQT---MTNVFVTSLAA 81

Query: 62  AASIMPLGLLAAPPPGL----GRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLI 117
           A  +M  GLL  PP       G   LG   C     +    + A    + AL + RY  +
Sbjct: 82  ADLVM--GLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAV 139

Query: 118 VHPLRPGSRPPPVLVLTAV---W---AAAGLLGALSLLGTPPAPPPAPA-----RCSVLA 166
            +PLR G+        TAV   W   AA      +S      A   A       RC   A
Sbjct: 140 TNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFA 199

Query: 167 GGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAA--LR-----------PPRPAR-- 211
             + P+  L + ++F LP L++L  Y  +FVVA R    LR           PP P+R  
Sbjct: 200 SNM-PYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSL 258

Query: 212 -----GSRLHSDSLDS---RLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACL- 262
                G+    + + +   R + L PLR      +A     L +G F  CWLP+  A + 
Sbjct: 259 APAPVGTCAPPEGVPACGRRPARLLPLREH----RALCTLGLIMGTFTLCWLPFFLANVL 314

Query: 263 ----APAARAAEAEAAVTWVAYSAFAAHPFLYGL---LQRPVRLALGRLSRRALPGPVRA 315
                P+     A  A+ W+ Y+  A +P +Y      +   R  L R  RR  P P  A
Sbjct: 315 RALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCGRRLPPEPCAA 374

Query: 316 CTP 318
             P
Sbjct: 375 ARP 377


>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
          Length = 398

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 100/356 (28%), Positives = 141/356 (39%), Gaps = 34/356 (9%)

Query: 18  LILAAVVEVGALLGNGALLVVVLRTPGLRDA--LYLAHLCVVDLLAAASIMPLGLLAAPP 75
           L  AA++ +G L+GN  ++ V+ R   +R     Y+A+L   D+      +P   L  P 
Sbjct: 47  LFFAALMLLG-LVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPL 105

Query: 76  PGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGSRPPPVLVLT- 134
           PG     LG   C+   ++    + A    + A+ + R+ + V PLR   R  P L L  
Sbjct: 106 PGWV---LGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAV 162

Query: 135 --AVWAAAGLLGALSLLGTPPAPPPAPARCSVL--AGGLGPFRPLWALLA-FALPALLLL 189
             ++W  +  + A  L     +P P  A CS    +  L     L+ LLA + LP L   
Sbjct: 163 SLSIWVGSAAVSAPVLALHRLSPGPR-AYCSEAFPSRALERAFALYNLLALYLLPLLATC 221

Query: 190 GAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQ 249
             Y  +     R A+RP  PA  S L    L  R   +          K +   A  V  
Sbjct: 222 ACYAAMLRHLGRVAVRPA-PA-DSALQGQVLAERAGAVR--------AKVSRLVAAVVLL 271

Query: 250 FAACWLPYGC----ACLAPAA----RAAEAEAAVTW---VAYSAFAAHPFLYGLLQRPVR 298
           FAACW P         L PA     R+  A A  TW   ++YS  A +P LY  L    R
Sbjct: 272 FAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFR 331

Query: 299 LALGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGG 354
            A  R+   A   P R   P    P A    L R    PA   ++ P  +   A G
Sbjct: 332 QAFRRVCPCAPRRPRRPRRPGPSDPAAPHAELLRLGSHPAPARAQKPGSSGLAARG 387


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 98/389 (25%), Positives = 142/389 (36%), Gaps = 82/389 (21%)

Query: 6   GLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAA 63
           G    E+  ++ + L AV+ + ++ GN  ++VV+  +  LR     +L  L V DLL A 
Sbjct: 46  GAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAV 105

Query: 64  SIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRP 123
           + MP  LL   P  +G    G   C+A  +L    +   TL + A+ L RY  I  PL+ 
Sbjct: 106 ACMPFTLL---PNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQA 162

Query: 124 ---GSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWA--- 177
               +R     V+ A W  +GLL     + T   P        V        R  W+   
Sbjct: 163 RVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLL 222

Query: 178 -LLAFALPALLLLGAYGGIF-----------------------------VVARRAALRPP 207
            LL F +P +++  AYG I                               V +    RP 
Sbjct: 223 LLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPE 282

Query: 208 RPARGSRLHSDSLDSRLSILPPLRPRL-------PGGKAALAPALA-------------- 246
             A G     +  D     LP  RP L       PG  +   P  A              
Sbjct: 283 TGAVG-----EDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLV 337

Query: 247 -VGQFAACWLPYGCACL-----APAARAAEAEAAVTWV---AYSAFAAHPFLYGLLQRPV 297
            V  F  CWLP   A        P A  A + A ++++   +Y++   +P +Y  + R  
Sbjct: 338 IVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRF 397

Query: 298 RLALGRLSRRALPGPVRACTPQAWHPRAL 326
           R A      R  P P RA       PRAL
Sbjct: 398 RQACLETCARCCPRPPRA------RPRAL 420


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 80/326 (24%), Positives = 132/326 (40%), Gaps = 46/326 (14%)

Query: 15  SLGLILAAVVEVGALLGNGALLVVV-----LRTPGLRDALYLAHLCVVDLLAAASIMPLG 69
           S+GL+L A + + A++GN  +++ V     LRTP      ++ +L + DLL + +++P  
Sbjct: 47  SVGLVLGAFI-LFAIVGNILVILSVACNRHLRTP---TNYFIVNLAMADLLLSFTVLPF- 101

Query: 70  LLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGS---R 126
             +A    LG   LG   C     +      A  L + A+ + RY  + + L+  +   R
Sbjct: 102 --SAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTR 159

Query: 127 PPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALL-AFALPA 185
              +L L +VW  + ++    LLG     P     C V      PF  L++ L +F +P 
Sbjct: 160 RKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEE---PFYALFSSLGSFYIPL 216

Query: 186 LLLLGAYGGIFVVARRAALRPPRPA--------------RGSRLHSDSLDS--------R 223
            ++L  Y  +++VA+R                            H D+L S        R
Sbjct: 217 AVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPR 276

Query: 224 LSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCA----CLAPAARAAEAE-AAVTWV 278
            SI   L       KAA    + VG F  CWLP+  A     L    +  +A    V W+
Sbjct: 277 SSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWL 336

Query: 279 AYSAFAAHPFLYGLLQRPVRLALGRL 304
            Y     +P +Y    +  + A  R+
Sbjct: 337 GYFNSCLNPIIYPCSSKEFKRAFVRI 362


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 85/321 (26%), Positives = 129/321 (40%), Gaps = 43/321 (13%)

Query: 2   ANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLLA 61
           A+S  L+++    ++ ++LA ++ +  + GN    VVV    GL   L     C +  LA
Sbjct: 7   ASSFCLDSTACKITITVVLAVLILI-TVAGN----VVVCLAVGLNRRLRNLTNCFIVSLA 61

Query: 62  AASIMPLGLLAAPPPGLGRVR----LGPAPCRAARFLSAALLPACTLGVAALGLARYRLI 117
              ++ LGLL  P   + ++      G   C     L   L  A  L +  + L RY  +
Sbjct: 62  ITDLL-LGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV 120

Query: 118 VHPLRPGSRPPPVLV---LTAVWAAAGLLGALSL-LGTPPAPPPAP-----ARCSVLAGG 168
           + PLR      PV V   L  +W  +  L  LS+ LG       +      ++C V    
Sbjct: 121 MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE 180

Query: 169 LGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILP 228
           +  +  +  L+ F LP L++   Y  IF VAR  A R          H  S  +      
Sbjct: 181 V--YGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRIN--------HISSWKAAT---- 226

Query: 229 PLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEA-----EAAVTWVAYSAF 283
                +   KA +  A  +G F  CW PY  A +    R  +A     EA V W+ Y+  
Sbjct: 227 -----IREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANS 281

Query: 284 AAHPFLYGLLQRPVRLALGRL 304
           A +P LY  L R  R    +L
Sbjct: 282 ALNPILYAALNRDFRTGYQQL 302


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 85/321 (26%), Positives = 129/321 (40%), Gaps = 43/321 (13%)

Query: 2   ANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLLA 61
           A+S  L+++    ++ ++LA ++ +  + GN    VVV    GL   L     C +  LA
Sbjct: 7   ASSFCLDSTACKITITVVLAVLILI-TVAGN----VVVCLAVGLNRRLRNLTNCFIVSLA 61

Query: 62  AASIMPLGLLAAPPPGLGRVR----LGPAPCRAARFLSAALLPACTLGVAALGLARYRLI 117
              ++ LGLL  P   + ++      G   C     L   L  A  L +  + L RY  +
Sbjct: 62  ITDLL-LGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV 120

Query: 118 VHPLRPGSRPPPVLV---LTAVWAAAGLLGALSL-LGTPPAPPPAP-----ARCSVLAGG 168
           + PLR      PV V   L  +W  +  L  LS+ LG       +      ++C V    
Sbjct: 121 MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE 180

Query: 169 LGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILP 228
           +  +  +  L+ F LP L++   Y  IF VAR  A R          H  S  +      
Sbjct: 181 V--YGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRIN--------HISSWKAAT---- 226

Query: 229 PLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEA-----EAAVTWVAYSAF 283
                +   KA +  A  +G F  CW PY  A +    R  +A     EA V W+ Y+  
Sbjct: 227 -----IREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANS 281

Query: 284 AAHPFLYGLLQRPVRLALGRL 304
           A +P LY  L R  R    +L
Sbjct: 282 ALNPILYAALNRDFRTGYQQL 302


>gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
          Length = 363

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 92/338 (27%), Positives = 124/338 (36%), Gaps = 41/338 (12%)

Query: 12  VAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLR---DALYLAHLCVVDLLAAASIMPL 68
           +AG L ++LA      ALL N  +L+    +  LR     + L +L +  LL AA  MP 
Sbjct: 8   LAGLLVMVLAV-----ALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPF 62

Query: 69  GLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGSRPP 128
            LL       GR    P  C+   FL   L     L VAAL   ++  +  PLR   R  
Sbjct: 63  TLLGVMR---GRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLR 119

Query: 129 P---VLVLTAVW----AAAGLLGALSLLGTPPA-------PPPAPARCSVLAGGLGPFRP 174
           P    L+L   W    A +G     S LG   A        PP P R    A     F  
Sbjct: 120 PRYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA-----FTA 174

Query: 175 LWALLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRL 234
               + F LP  +L      +  VARR   R       +      L   +     ++ + 
Sbjct: 175 TLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKR 234

Query: 235 PGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTW------VAYSAFAAHPF 288
              +A     +A+  F  C+ PY    LA         A   W      + YS   A PF
Sbjct: 235 RRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNA--QWGILSKCLTYSKAVADPF 292

Query: 289 LYGLLQRPVRLALGRLSRRALPGPVRACTPQAWHPRAL 326
            Y LL+RP R  L  +  R L    R   P + H  +L
Sbjct: 293 TYSLLRRPFRQVLAGMVHRLLK---RTPRPASTHDSSL 327


>gi|23463303 purinergic receptor P2Y11 [Homo sapiens]
          Length = 374

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 94/347 (27%), Positives = 123/347 (35%), Gaps = 82/347 (23%)

Query: 49  LYLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAA 108
           ++   L V DLL A ++ PL     PP      R G A CR  RFL    L    + +  
Sbjct: 66  VFSVQLAVSDLLCALTLPPLAAYLYPPK---HWRYGEAACRLERFLFTCNLLGSVIFITC 122

Query: 109 LGLARYRLIVHPL--RPGSRPPPVLVLTAV-WAAAGLLG----ALSLLGTPP-------- 153
           + L RY  IVHP   R   RP     ++A  W  A LL     + S L  P         
Sbjct: 123 ISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSV 182

Query: 154 APPPAPARCSVLAG-GLGPFRPLWALLA---FALPALLLLGAYGGIFVVARRAALRPPRP 209
           A P A  +C   A  GL  +R    +LA     LP LL L AYG +     RA LR P  
Sbjct: 183 ARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGAL----GRAVLRSPGM 238

Query: 210 ARGSRLHSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPY------------ 257
               +L                      + A   A  V  +A+ ++PY            
Sbjct: 239 TVAEKL----------------------RVAALVASGVALYASSYVPYHIMRVLNVDARR 276

Query: 258 ----GCACLAPAARAAEAEAAVTWVAYS--------AFAAHPFLYGLLQRPVRLALGRLS 305
                C   A  A+A  A     +V Y         AF  HP LY +   P   +LG   
Sbjct: 277 RWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLY-MAAVP---SLGCCC 332

Query: 306 RRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELA 352
           R   PG        +W+P       Q  P      P  +  Q+ EL+
Sbjct: 333 RHC-PG-----YRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELS 373


>gi|99028871 PPAN-P2RY11 protein [Homo sapiens]
          Length = 794

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 94/347 (27%), Positives = 123/347 (35%), Gaps = 82/347 (23%)

Query: 49  LYLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAA 108
           ++   L V DLL A ++ PL     PP      R G A CR  RFL    L    + +  
Sbjct: 486 VFSVQLAVSDLLCALTLPPLAAYLYPPK---HWRYGEAACRLERFLFTCNLLGSVIFITC 542

Query: 109 LGLARYRLIVHPL--RPGSRPPPVLVLTAV-WAAAGLLG----ALSLLGTPP-------- 153
           + L RY  IVHP   R   RP     ++A  W  A LL     + S L  P         
Sbjct: 543 ISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSV 602

Query: 154 APPPAPARCSVLAG-GLGPFRPLWALLA---FALPALLLLGAYGGIFVVARRAALRPPRP 209
           A P A  +C   A  GL  +R    +LA     LP LL L AYG +     RA LR P  
Sbjct: 603 ARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGAL----GRAVLRSPGM 658

Query: 210 ARGSRLHSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPY------------ 257
               +L                      + A   A  V  +A+ ++PY            
Sbjct: 659 TVAEKL----------------------RVAALVASGVALYASSYVPYHIMRVLNVDARR 696

Query: 258 ----GCACLAPAARAAEAEAAVTWVAYS--------AFAAHPFLYGLLQRPVRLALGRLS 305
                C   A  A+A  A     +V Y         AF  HP LY +   P   +LG   
Sbjct: 697 RWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLY-MAAVP---SLGCCC 752

Query: 306 RRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELA 352
           R   PG        +W+P       Q  P      P  +  Q+ EL+
Sbjct: 753 RHC-PG-----YRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELS 793


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 97/409 (23%), Positives = 155/409 (37%), Gaps = 60/409 (14%)

Query: 6   GLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAA 63
           GL  S     +G+ LAA + + A+ GN  +++ V     L+     ++ +L V DLL +A
Sbjct: 89  GLVVSAQGVGVGVFLAAFILM-AVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSA 147

Query: 64  SIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLR- 122
           +++P    +A    LG    G A C     +      A  L +  + + RY  + H L+ 
Sbjct: 148 TVLP---FSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKY 204

Query: 123 PG--SRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVL-AGGLGPFRPLWALL 179
           P   +      +L  +W  A ++    LLG     PP    C +    G   F    ++ 
Sbjct: 205 PAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFS---SVC 261

Query: 180 AFALPALLLLGAYGGIFVVAR------RAALRPPR----------PARGSRLHSDSLDS- 222
           +F LP  +++  Y  ++VVAR       A ++  R            RG+   +D     
Sbjct: 262 SFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGM 321

Query: 223 --------RLSILPPLRPRLPGGKAALAPALAVGQFAACWLPY----GCACLAPAARAAE 270
                   R S+   L       KAA   A+ VG F  CW P+        L P  + +E
Sbjct: 322 RSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSE 381

Query: 271 AE-AAVTWVAYSAFAAHPFLYGLLQRPVRLALGRL-----SRRALPGPVRACTPQAWHPR 324
                + W+ Y     +P +Y    R  + A  RL      RR    P+       W  R
Sbjct: 382 GVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHW--R 439

Query: 325 ALLQCLQR--------PPEGPAVGPSEAPEQTPELAGGRSPAYQGPPES 365
           A    L++         P G  +  +  P+  PE  G  +P  Q P  S
Sbjct: 440 ASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPG--TPEMQAPVAS 486


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 75/312 (24%), Positives = 123/312 (39%), Gaps = 51/312 (16%)

Query: 16  LGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA 73
           LG+IL  ++  G +LGN  +++ V     L      Y+ +L V DLL  ++++P   +  
Sbjct: 29  LGVILGGLILFG-VLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87

Query: 74  PPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGS---RPPPV 130
               LG    G   C     +      A  +G+  + + RY  + +PLR  +   +   +
Sbjct: 88  V---LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGL 144

Query: 131 LVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALL-AFALPALLLL 189
           + L  VWA + ++    L G     P     C +      P   L++ L +F LP  ++L
Sbjct: 145 MALLCVWALSLVISIGPLFGWRQPAPEDETICQI---NEEPGYVLFSALGSFYLPLAIIL 201

Query: 190 GAYGGIFVVARRAALRPPRPARG--SRLHSDSLDSRLSILPPLRPRLPGGKAALAPA--- 244
             Y  ++VVA+R +       RG  S L +D  DS    L   R   P G + +A A   
Sbjct: 202 VMYCRVYVVAKRES-------RGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTK 254

Query: 245 ---------------------LAVGQFAACWLPY----GCACLAPAARAAEAE-AAVTWV 278
                                + VG F  CWLP+          P  + +E     V W+
Sbjct: 255 THFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWL 314

Query: 279 AYSAFAAHPFLY 290
            Y     +P +Y
Sbjct: 315 GYLNSCINPIIY 326


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 75/312 (24%), Positives = 123/312 (39%), Gaps = 51/312 (16%)

Query: 16  LGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA 73
           LG+IL  ++  G +LGN  +++ V     L      Y+ +L V DLL  ++++P   +  
Sbjct: 29  LGVILGGLILFG-VLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87

Query: 74  PPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGS---RPPPV 130
               LG    G   C     +      A  +G+  + + RY  + +PLR  +   +   +
Sbjct: 88  V---LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGL 144

Query: 131 LVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALL-AFALPALLLL 189
           + L  VWA + ++    L G     P     C +      P   L++ L +F LP  ++L
Sbjct: 145 MALLCVWALSLVISIGPLFGWRQPAPEDETICQI---NEEPGYVLFSALGSFYLPLAIIL 201

Query: 190 GAYGGIFVVARRAALRPPRPARG--SRLHSDSLDSRLSILPPLRPRLPGGKAALAPA--- 244
             Y  ++VVA+R +       RG  S L +D  DS    L   R   P G + +A A   
Sbjct: 202 VMYCRVYVVAKRES-------RGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTK 254

Query: 245 ---------------------LAVGQFAACWLPY----GCACLAPAARAAEAE-AAVTWV 278
                                + VG F  CWLP+          P  + +E     V W+
Sbjct: 255 THFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWL 314

Query: 279 AYSAFAAHPFLY 290
            Y     +P +Y
Sbjct: 315 GYLNSCINPIIY 326


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 75/312 (24%), Positives = 123/312 (39%), Gaps = 51/312 (16%)

Query: 16  LGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA 73
           LG+IL  ++  G +LGN  +++ V     L      Y+ +L V DLL  ++++P   +  
Sbjct: 29  LGVILGGLILFG-VLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87

Query: 74  PPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGS---RPPPV 130
               LG    G   C     +      A  +G+  + + RY  + +PLR  +   +   +
Sbjct: 88  V---LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGL 144

Query: 131 LVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALL-AFALPALLLL 189
           + L  VWA + ++    L G     P     C +      P   L++ L +F LP  ++L
Sbjct: 145 MALLCVWALSLVISIGPLFGWRQPAPEDETICQI---NEEPGYVLFSALGSFYLPLAIIL 201

Query: 190 GAYGGIFVVARRAALRPPRPARG--SRLHSDSLDSRLSILPPLRPRLPGGKAALAPA--- 244
             Y  ++VVA+R +       RG  S L +D  DS    L   R   P G + +A A   
Sbjct: 202 VMYCRVYVVAKRES-------RGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTK 254

Query: 245 ---------------------LAVGQFAACWLPY----GCACLAPAARAAEAE-AAVTWV 278
                                + VG F  CWLP+          P  + +E     V W+
Sbjct: 255 THFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWL 314

Query: 279 AYSAFAAHPFLY 290
            Y     +P +Y
Sbjct: 315 GYLNSCINPIIY 326


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 75/312 (24%), Positives = 123/312 (39%), Gaps = 51/312 (16%)

Query: 16  LGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA 73
           LG+IL  ++  G +LGN  +++ V     L      Y+ +L V DLL  ++++P   +  
Sbjct: 29  LGVILGGLILFG-VLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE 87

Query: 74  PPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGS---RPPPV 130
               LG    G   C     +      A  +G+  + + RY  + +PLR  +   +   +
Sbjct: 88  V---LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGL 144

Query: 131 LVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALL-AFALPALLLL 189
           + L  VWA + ++    L G     P     C +      P   L++ L +F LP  ++L
Sbjct: 145 MALLCVWALSLVISIGPLFGWRQPAPEDETICQI---NEEPGYVLFSALGSFYLPLAIIL 201

Query: 190 GAYGGIFVVARRAALRPPRPARG--SRLHSDSLDSRLSILPPLRPRLPGGKAALAPA--- 244
             Y  ++VVA+R +       RG  S L +D  DS    L   R   P G + +A A   
Sbjct: 202 VMYCRVYVVAKRES-------RGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTK 254

Query: 245 ---------------------LAVGQFAACWLPY----GCACLAPAARAAEAE-AAVTWV 278
                                + VG F  CWLP+          P  + +E     V W+
Sbjct: 255 THFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWL 314

Query: 279 AYSAFAAHPFLY 290
            Y     +P +Y
Sbjct: 315 GYLNSCINPIIY 326


>gi|32261309 G protein-coupled receptor 135 [Homo sapiens]
          Length = 494

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 86/322 (26%), Positives = 127/322 (39%), Gaps = 49/322 (15%)

Query: 9   ASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDAL--YLAHLCVVDLLAAASIM 66
           A+  A +L L+L  ++   + LGN A++ V+++   LR     ++  L + DLL A   +
Sbjct: 101 AAVAAQALVLLLIFLL---SSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCL 157

Query: 67  PLGLLAA-PPPGLGRVRLGPAP----CRAARFLSAALLPACTLGVAALGLARYRLIVHPL 121
           P   L    PPG         P    C A+RF S+      TL VA + L RY  IV P 
Sbjct: 158 PAAFLDLFTPPGGSAPAAAAGPWRGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPP 217

Query: 122 RP--GSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPA------RCSVLAGGLGPFR 173
           R   G R    L+  A   A G      LLG P     A +      R S     LG   
Sbjct: 218 REKIGRRRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAF 277

Query: 174 PLWALLA-FALPALLLLGAYGGIFVVARRAALRPPRP----ARGSRLHSDSLDSRLSILP 228
            +  ++A + LP LL+   +  I    R + +R  RP    AR  R  S+          
Sbjct: 278 SVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRV-RPVNTYARVLRFFSEV--------- 327

Query: 229 PLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEAEAA-------VTWVAYS 281
                    + A    + +     CW PY    L  AAR A+   A         W+ ++
Sbjct: 328 ---------RTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLTWA 378

Query: 282 AFAAHPFLYGLLQRPVRLALGR 303
             A +P +Y +    + + LGR
Sbjct: 379 NGAINPVIYAIRNPNISMLLGR 400


>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
          Length = 370

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 80/311 (25%), Positives = 124/311 (39%), Gaps = 36/311 (11%)

Query: 11  EVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDA--LYLAHLCVVDLLAAASIMPL 68
           ++ G + L+ + VV VG L+GN  L++V+ R   L +     + +L + D+L   + +PL
Sbjct: 58  QLKGLIVLLYSVVVVVG-LVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPL 116

Query: 69  GLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPG-SRP 127
            L  A  P  G V  G   C    FL    +      +  + + RY ++VHPLR   S  
Sbjct: 117 TLAYAFEPR-GWV-FGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLR 174

Query: 128 PPVLVLTAVWAAAGLLGALSLLGT--PPAPPPAPARCSVLAGGLGPFRPLWA----LLAF 181
                + A+WA + +L   + + T      P     C    G     R L+A    L+ +
Sbjct: 175 LSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTY 234

Query: 182 ALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAAL 241
            LP L++L +Y  + V  R   +  P     S+   D    R              +   
Sbjct: 235 LLPLLVILLSYVRVSVKLRNRVV--PGCVTQSQADWDRARRR--------------RTFC 278

Query: 242 APALAVGQFAACWLPYG----CACLAPAARAAEAEAAVT----WVAYSAFAAHPFLYGLL 293
              + V  FA CWLP         L P A    A   V     W+A S+   +PF+Y  L
Sbjct: 279 LLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWL 338

Query: 294 QRPVRLALGRL 304
               R  L +L
Sbjct: 339 HDSFREELRKL 349


>gi|9506745 urotensin 2 receptor [Homo sapiens]
          Length = 389

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 101/371 (27%), Positives = 141/371 (38%), Gaps = 59/371 (15%)

Query: 14  GSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDA----LYLAHLCVVDLLAAASIMPLG 69
           G++G +L+A+  VG ++GN   LVV  R+  LR      +Y+ +L + DLL   SI  + 
Sbjct: 52  GTIGTLLSAMGVVG-VVGNAYTLVVTCRS--LRAVASMYVYVVNLALADLLYLLSIPFIV 108

Query: 70  LLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGSRPPP 129
                         G   CR    L    + A    +  +   RY  ++ PL    RP  
Sbjct: 109 ATYVTKEW----HFGDVGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKG 164

Query: 130 VLVLTAV--WAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALL---AFALP 184
              L A+  W  A LL  L ++         P    + A G    R    LL   + A P
Sbjct: 165 YRKLLALGTWLLALLL-TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGP 223

Query: 185 ALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAALAPA 244
            LL+    G ++    RA  R  R +                    R R PG +A     
Sbjct: 224 GLLI----GLLYARLARAYRRSQRASFK------------------RARRPGARALRLVL 261

Query: 245 LAVGQFAACWLP---------YGCACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQR 295
             V  F AC+LP         Y  A LAP   A       T + Y    A+PFLY LL R
Sbjct: 262 GIVLLFWACFLPFWLWQLLAQYHQAPLAPRT-ARIVNYLTTCLTYGNSCANPFLYTLLTR 320

Query: 296 PVRLAL-GRL---SRRALPGPVRACTPQA----WHPRALLQCLQRPPEGPAVGPSEAPEQ 347
             R  L GR+         GPV +  P+A       R+L  C  +P +   + P+     
Sbjct: 321 NYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLSSCSPQPTDSLVLAPAAPARP 380

Query: 348 TPELAGGRSPA 358
            PE  G R+PA
Sbjct: 381 APE--GPRAPA 389


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 88/311 (28%), Positives = 121/311 (38%), Gaps = 57/311 (18%)

Query: 6   GLNASEVAGSLGL--ILAAVVEVGALLGNGALLVVVLRTPGLRDA--LYLAHLCVVDLLA 61
           G   +  AG + +  I A V  VG L+GN  ++ V+LR   ++ A  +YL +L V D L 
Sbjct: 38  GPGDARAAGMVAIQCIYALVCLVG-LVGNALVIFVILRYAKMKTATNIYLLNLAVADELF 96

Query: 62  AASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPL 121
             S+  +   AA    L     G   CRA   +    +      +  L + RY  +VHPL
Sbjct: 97  MLSVPFVASSAA----LRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPL 152

Query: 122 RPGS-RPPPV--LVLTAVWAAAGLLGALSLLGTPPA---PPPAPAR-CSVLAGGLGPFRP 174
           R  + R P V  L+   VW A       SLL T P        PAR    +A  L    P
Sbjct: 153 RAATYRRPSVAKLINLGVWLA-------SLLVTLPIAIFADTRPARGGQAVACNLQWPHP 205

Query: 175 LWA--------LLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSI 226
            W+        LL F LP L +   Y  I    R  AL   R     R  S+   +RL +
Sbjct: 206 AWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVAL---RAGWQQRRRSEKKITRLVL 262

Query: 227 LPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWV----AYSA 282
                             + V  F  CW+P+    L         +A V  V    +Y+ 
Sbjct: 263 ------------------MVVVVFVLCWMPFYVVQLLNLF-VTSLDATVNHVSLILSYAN 303

Query: 283 FAAHPFLYGLL 293
             A+P LYG L
Sbjct: 304 SCANPILYGFL 314


>gi|4557861 somatostatin receptor 3 [Homo sapiens]
          Length = 418

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 89/358 (24%), Positives = 125/358 (34%), Gaps = 65/358 (18%)

Query: 12  VAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLLAAASIMPLGL- 70
           V+G L  ++  VV V  LLGN  ++ VVLR      +  + ++ +++L  A  +  LGL 
Sbjct: 42  VSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA---SPSVTNVYILNLALADELFMLGLP 98

Query: 71  LAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGS-RPPP 129
             A    L     G   CR    +           +  + + RY  +VHP R    R  P
Sbjct: 99  FLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP 158

Query: 130 V--LVLTAVWAAAG--LLGALSLLGTPPAPP------PAPARCSVLAGGLGPFRPLWALL 179
           V   V  AVW A+   +L  +   G P          P PA     A     F    A L
Sbjct: 159 VARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPA-----AAWRAGFIIYTAAL 213

Query: 180 AFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKA 239
            F  P L++   Y  I V  R A  R   P+   R  S+   +R+ +             
Sbjct: 214 GFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVV------------- 260

Query: 240 ALAPALAVGQFAACWLPYGCACLAPAARAAEAEAA-------VTWVAYSAFAAHPFLYGL 292
                  V  F  CW+P+    +         E A       V  + Y+   A+P LYG 
Sbjct: 261 -----AVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGF 315

Query: 293 LQRPVRLALGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPE 350
           L    +       RR L  P R    Q                 P VGP E  E+  E
Sbjct: 316 LSYRFKQGF----RRVLLRPSRRVRSQE----------------PTVGPPEKTEEEDE 353



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 10/102 (9%)

Query: 57  VDLLAAASIM----PLGLLAAPPPG--LGRVRLGPAPCRAARFLSAALLPACTLGVAALG 110
           +D+L  +S+     P    +A PP   LG V  GP+P   A  +S  L+P   L V  +G
Sbjct: 1   MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLA--VSGVLIPLVYLVVCVVG 58

Query: 111 LARYRLIVHPLRPGSRPPPVLVLTAVWAAAGLLGALSLLGTP 152
           L    L+++ +   +  P V  +  +  A  L   L +LG P
Sbjct: 59  LLGNSLVIYVVLRHTASPSVTNVYILNLA--LADELFMLGLP 98


>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
           sapiens]
          Length = 390

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 77/337 (22%), Positives = 124/337 (36%), Gaps = 52/337 (15%)

Query: 18  LILAAVVEVGALLGNGALLVVVLRTPGLRD-ALYL-AHLCVVDLLAAASIMPLGLLAAPP 75
           ++L A++ +   L N  ++  V RT  L   A YL A L V DLL +  +MP+  +    
Sbjct: 53  VMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVT 112

Query: 76  PGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGSRPPP---VLV 132
              GR  LG   C            A  L +  + L RY  I   +   ++  P    ++
Sbjct: 113 ---GRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVM 169

Query: 133 LTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAY 192
           +  VW  +  +                + C V    +  +     + AF  P LLL+  Y
Sbjct: 170 IALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHI-LYTVYSTVGAFYFPTLLLIALY 228

Query: 193 GGIFVVARRAALR--PPRPAR------------GSRLHSDSLDSRLSILP---------- 228
           G I+V AR   L+  P R  +            GS     S++SR+  +P          
Sbjct: 229 GRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVN 288

Query: 229 PLRPRLPGG-------------KAALAPALAVGQFAACWLPYGCACLA-PAAR-AAEAEA 273
            ++ R+                KA     + +G F  CWLP+    L  P  + A     
Sbjct: 289 QVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHL 348

Query: 274 AV----TWVAYSAFAAHPFLYGLLQRPVRLALGRLSR 306
           A+    TW+ Y     +P +Y +     + A  +L R
Sbjct: 349 AIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIR 385


>gi|5174595 melatonin receptor 1B [Homo sapiens]
          Length = 362

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 83/351 (23%), Positives = 134/351 (38%), Gaps = 58/351 (16%)

Query: 12  VAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDA--LYLAHLCVVDLLAAASIMPLG 69
           VA +L  +L     V  ++GN  +++ VLR   LR+A  L+L  L + DL+ A    PL 
Sbjct: 39  VAPALSAVLIVTTAVD-VVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLI 97

Query: 70  LLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPL---RPGSR 126
           L+A    G     LG   C+A+ F+    +      + A+ + RY  I H +   R   R
Sbjct: 98  LVAIFYDGWA---LGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRR 154

Query: 127 PPPVLVLTAVWAAAGLLGALSLLGT----PPAPPPAPARCSVLAGGLGPFRPLWALLAFA 182
               L +  +W    LL  ++LL           P    C+ +      +     ++ F 
Sbjct: 155 WHTPLHICLIW----LLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFL 210

Query: 183 LPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAALA 242
           LP  ++   Y  I+V+  +A  R  +P           +SRL + P         ++ L 
Sbjct: 211 LPIAVVSFCYLRIWVLVLQAR-RKAKP-----------ESRLCLKPS------DLRSFLT 252

Query: 243 PALAVGQFAACWLPYGCACLAPAARAAEAEAAVT--------WVAYSAFAAHPFLYGLLQ 294
             +    FA CW P  C  LA A    E    +          +AY     +  +YGLL 
Sbjct: 253 MFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLN 312

Query: 295 RPVRLALGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAP 345
           +  R    R+                W+PR    C+Q   +G      ++P
Sbjct: 313 QNFRREYKRI------------LLALWNPR---HCIQDASKGSHAEGLQSP 348


>gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
           sapiens]
          Length = 386

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 77/293 (26%), Positives = 110/293 (37%), Gaps = 23/293 (7%)

Query: 8   NASEVAGSLGLILAAVVEVGALLGNG-ALLVVVLRTPGLRDA--LYLAHLCVVDLLAAAS 64
           N + V GS+G   + ++ V  ++GNG AL ++  R P    A  + +  L   DLL  + 
Sbjct: 7   NLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSF 66

Query: 65  IMPLGLLAAPPPG--LGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLR 122
           + P   +A       LG  R GPA C A  F       A  L + A+ + R   + HP  
Sbjct: 67  LSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYL 126

Query: 123 PGSRPPP---VLVLTAVWAAAGLLGALSLLGTPPAPPPAPAR-CSVLAGGLGPFRPLWAL 178
                 P    L L A++A   L  AL LLG        P   C +      P    ++L
Sbjct: 127 YAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSL 186

Query: 179 LAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGK 238
               L ALL+      IF+      L   R  R  + H  SL          RPR    +
Sbjct: 187 AYAGLVALLV----AAIFLCNGSVTLSLCRMYRQQKRHQGSLGP--------RPRTGEDE 234

Query: 239 A--ALAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWVAYSAFAAHPFL 289
               +  AL     A C LP    C   A     +      +A+  +A +P L
Sbjct: 235 VDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPIL 287


>gi|32483397 dopamine receptor D4 [Homo sapiens]
          Length = 419

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 64/268 (23%), Positives = 102/268 (38%), Gaps = 30/268 (11%)

Query: 4   STGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDA---LYLAHLCVVDLL 60
           S G +A         ++  V+ +GA+L   +L+ V + T          ++  L   DLL
Sbjct: 23  SAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLL 82

Query: 61  AAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHP 120
            A  ++PL + +    G     L P  C A   +   L  A    + A+ + R+  +  P
Sbjct: 83  LALLVLPLFVYSEVQGGAWL--LSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVP 140

Query: 121 L---RPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWA 177
           L   R G     +L++ A W  +  + A  L G        PA C +       +    +
Sbjct: 141 LRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYS---S 197

Query: 178 LLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGG 237
           + +F LP  L+L  Y   F       L+    AR ++LH  +         P RP  PG 
Sbjct: 198 VCSFFLPCPLMLLLYWATF-----RGLQRWEVARRAKLHGRA---------PRRPSGPGP 243

Query: 238 KAALAPALAVGQFAACWLPYGCACLAPA 265
            +   PA  + Q      P G  C  PA
Sbjct: 244 PSPTPPAPRLPQD-----PCGPDCAPPA 266



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 56/188 (29%), Positives = 73/188 (38%), Gaps = 38/188 (20%)

Query: 151 TPPAP----PPAPARCSVLAGGL--GPFRPLWALLAFALPALLLLGAYGGIFVVARRAAL 204
           TPPAP     P    C+  A GL  GP  P  A  A +LP        G     A  A  
Sbjct: 247 TPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQ----DPCGPD--CAPPAPG 300

Query: 205 RPPRPARGSRLHSDSLDSRLSILPPLRP---------RLPGG--KAALAPALAVGQFAAC 253
            PP P   +    D++  R + LPP  P         ++ G   KA     + VG F  C
Sbjct: 301 LPPDPCGSNCAPPDAV--RAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLC 358

Query: 254 WLPYGCA----CLAPAARAA-EAEAAVTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRA 308
           W P+        L PA        +AVTW+ Y   A +P +Y +     R     + R+A
Sbjct: 359 WTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFR----NVFRKA 414

Query: 309 LPGPVRAC 316
           L    RAC
Sbjct: 415 L----RAC 418


>gi|4503907 galanin receptor 3 [Homo sapiens]
          Length = 368

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 99/387 (25%), Positives = 135/387 (34%), Gaps = 86/387 (22%)

Query: 14  GSLGLILAAVVEVGALL----GNGALLVVVLRT-------PGLRDALYLAHLCVVDLLAA 62
           GS+G +   VV     L    GNG +L V+L+        PG    L++ +L V DL   
Sbjct: 13  GSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFI 72

Query: 63  ASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLR 122
              +P     A    L     G   C+A   L    + A +  +AA+ + RY  + HPLR
Sbjct: 73  LCCVPF---QATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLR 129

Query: 123 PGSRPPPVLVLTA---VWAAAGLLGA--LSLLGTPPAPPPAPARCSVLAGGLGPFRPLWA 177
             +   P     A   VW  A L  A  LS  GT            V  G L    P W 
Sbjct: 130 SRALRTPRNARAAVGLVWLLAALFSAPYLSYYGT------------VRYGALELCVPAWE 177

Query: 178 ------------LLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLS 225
                          + LP  ++  AYG        AA+ P   A        + ++R  
Sbjct: 178 DARRRALDVATFAAGYLLPVAVVSLAYGRTLRFL-WAAVGPAGAA--------AAEAR-- 226

Query: 226 ILPPLRPRLPGGKAALAPALAVGQFAACWLP---------YGCACLAPAARAAEAEAAVT 276
                  R   G+A  A       +A CW P         YG    +PA  A     A  
Sbjct: 227 -------RRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYA--CRLASH 277

Query: 277 WVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQAWH-PRALLQCLQRPPE 335
            +AY+    +P +Y L  R  R    RL           C  +  H  R  L+ ++    
Sbjct: 278 CLAYANSCLNPLVYALASRHFRARFRRL---------WPCGRRRRHRARRALRRVRPASS 328

Query: 336 GPAVGPSEAPEQTPELAGGRSPAYQGP 362
           GP   P +A      LAGG     QGP
Sbjct: 329 GPPGCPGDARPSGRLLAGGG----QGP 351


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 97/396 (24%), Positives = 144/396 (36%), Gaps = 72/396 (18%)

Query: 8   NASEVAGSLG---------LILAAVVEVGALLGNGALLVVVLRTPGLRDA--LYLAHLCV 56
           NAS+  G  G         L+ A +  VG + GN  +L V+LR         L++ +L V
Sbjct: 11  NASQAGGGGGWHPEAVIVPLLFALIFLVGTV-GNTLVLAVLLRGGQAVSTTNLFILNLGV 69

Query: 57  VDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRL 116
            DL      +P         G      G   C+A  FL    + A +  +AA+ L RY  
Sbjct: 70  ADLCFILCCVPFQATIYTLDGWV---FGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLA 126

Query: 117 IVHPLRPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLW 176
           I +PL       P   L    AA GL+  LSLL +   P  +  R S LA  L    P W
Sbjct: 127 IRYPLHSRELRTPRNAL----AAIGLIWGLSLLFS--GPYLSYYRQSQLA-NLTVCHPAW 179

Query: 177 A------------LLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRL 224
           +            + ++ LP L+L   Y        R A+ P     G+R     +   +
Sbjct: 180 SAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWR-AVDPVAAGSGARRAKRKVTRMI 238

Query: 225 SILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLA------PAARAAEAEAAVT-W 277
            I+  L                   F  CW+P+    L       P  RA  A   ++  
Sbjct: 239 LIVAAL-------------------FCLCWMPHHALILCVWFGQFPLTRATYALRILSHL 279

Query: 278 VAYSAFAAHPFLYGLLQRPVR-----LALGRLSRRALPGPVRAC-TPQAWHPRALLQ--- 328
           V+Y+    +P +Y L+ +  R     +  G L R       R C   +  H  ++L+   
Sbjct: 280 VSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERES 339

Query: 329 --CLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGP 362
              L       A+ P     Q   L     P++QGP
Sbjct: 340 SDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGP 375


>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
           sapiens]
          Length = 384

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 57/204 (27%), Positives = 81/204 (39%), Gaps = 13/204 (6%)

Query: 14  GSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALY----LAHLCVVDLLAAASIMPLG 69
           G LG +    V    L+    LLV+   T  +R   +    L ++ + DLL  A+ +   
Sbjct: 44  GGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANV 103

Query: 70  LLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGSRPPP 129
           LL+    G    RL PA       L    L A T  +      R+  +V P+        
Sbjct: 104 LLS----GARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKT 159

Query: 130 VLVLTAV---WAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPAL 186
             V   +   W  A LLG L LLG       A  RCS L         L+ L+ FA    
Sbjct: 160 SRVYGFIGLCWLLAALLGMLPLLGWNCLC--AFDRCSSLLPLYSKRYILFCLVIFAGVLA 217

Query: 187 LLLGAYGGIFVVARRAALRPPRPA 210
            ++G YG IF + + +  + PRPA
Sbjct: 218 TIMGLYGAIFRLVQASGQKAPRPA 241


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 40/133 (30%), Positives = 57/133 (42%), Gaps = 15/133 (11%)

Query: 176 WAL---LAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRP 232
           W L   L+F +P  +++  YG IF+VARR A +       +   S+S  +R++     R 
Sbjct: 198 WVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVA----RRE 253

Query: 233 RLPGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEAEAAV----TWVAYSAFAAHPF 288
           R    KAA    + V  F   WLPY    L  A       A +     W AY   A +P 
Sbjct: 254 R----KAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPL 309

Query: 289 LYGLLQRPVRLAL 301
           +Y L     R A+
Sbjct: 310 IYALFYPWFRKAI 322


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,265,862
Number of Sequences: 37866
Number of extensions: 1074931
Number of successful extensions: 7354
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 379
Number of HSP's that attempted gapping in prelim test: 6764
Number of HSP's gapped (non-prelim): 827
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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