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Search of human proteins with 144226225
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
(555 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 1133 0.0
gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens] 1122 0.0
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 1092 0.0
gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens] 1080 0.0
gi|123173752 synaptotagmin XIV-like [Homo sapiens] 436 e-122
gi|209447073 synaptotagmin I [Homo sapiens] 122 9e-28
gi|5032139 synaptotagmin I [Homo sapiens] 122 9e-28
gi|209447070 synaptotagmin I [Homo sapiens] 122 9e-28
gi|39752671 synaptotagmin X [Homo sapiens] 115 1e-25
gi|211059429 synaptotagmin II [Homo sapiens] 111 2e-24
gi|31543670 synaptotagmin II [Homo sapiens] 111 2e-24
gi|24308219 synaptotagmin IV [Homo sapiens] 110 3e-24
gi|216548478 synaptotagmin XI [Homo sapiens] 107 3e-23
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 105 1e-22
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 105 1e-22
gi|45504376 synaptotagmin VI [Homo sapiens] 105 1e-22
gi|38570146 synaptotagmin VII [Homo sapiens] 104 2e-22
gi|238550198 synaptotagmin III [Homo sapiens] 100 3e-21
gi|238550196 synaptotagmin III [Homo sapiens] 100 3e-21
gi|14150054 synaptotagmin III [Homo sapiens] 100 3e-21
gi|92859638 synaptotagmin V [Homo sapiens] 99 1e-20
gi|28376627 synaptotagmin IX [Homo sapiens] 94 4e-19
gi|6005997 double C2-like domains, beta [Homo sapiens] 92 2e-18
gi|40068038 B/K protein [Homo sapiens] 88 2e-17
gi|29366828 synaptotagmin XII [Homo sapiens] 88 2e-17
gi|47078261 double C2-like domains, alpha [Homo sapiens] 83 6e-16
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 83 8e-16
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 81 3e-15
gi|94536846 synaptotagmin VIII [Homo sapiens] 79 8e-15
gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 68 2e-11
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 1133 bits (2931), Expect = 0.0
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPD 60
MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPD
Sbjct: 1 MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPD 60
Query: 61 LGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRN 120
LGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRN
Sbjct: 61 LGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRN 120
Query: 121 YAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT 180
YAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT
Sbjct: 121 YAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT 180
Query: 181 PSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDM 240
PSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDM
Sbjct: 181 PSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDM 240
Query: 241 SAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQV 300
SAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQV
Sbjct: 241 SAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQV 300
Query: 301 HLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVG 360
HLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVG
Sbjct: 301 HLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVG 360
Query: 361 EKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEIL 420
EKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEIL
Sbjct: 361 EKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEIL 420
Query: 421 IGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPN 480
IGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPN
Sbjct: 421 IGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPN 480
Query: 481 PVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKE 540
PVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKE
Sbjct: 481 PVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKE 540
Query: 541 SKGQQVCRWHALLES 555
SKGQQVCRWHALLES
Sbjct: 541 SKGQQVCRWHALLES 555
>gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens]
Length = 574
Score = 1122 bits (2901), Expect = 0.0
Identities = 555/574 (96%), Positives = 555/574 (96%), Gaps = 19/574 (3%)
Query: 1 MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPD 60
MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPD
Sbjct: 1 MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPD 60
Query: 61 LGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRN 120
LGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRN
Sbjct: 61 LGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRN 120
Query: 121 YAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT 180
YAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT
Sbjct: 121 YAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT 180
Query: 181 PSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDM 240
PSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDM
Sbjct: 181 PSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDM 240
Query: 241 SAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQV 300
SAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQV
Sbjct: 241 SAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQV 300
Query: 301 HLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVG 360
HLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVG
Sbjct: 301 HLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVG 360
Query: 361 EKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEIL 420
EKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEIL
Sbjct: 361 EKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEIL 420
Query: 421 IGLLYNATTGRLSAEVIKGSHFKNLAANRPPN-------------------TYVKLTLLN 461
IGLLYNATTGRLSAEVIKGSHFKNLAANRPPN TYVKLTLLN
Sbjct: 421 IGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLN 480
Query: 462 SMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWIS 521
SMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWIS
Sbjct: 481 SMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWIS 540
Query: 522 LGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 555
LGLNSSGEEELNHWTEMKESKGQQVCRWHALLES
Sbjct: 541 LGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 574
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 1092 bits (2823), Expect = 0.0
Identities = 535/535 (100%), Positives = 535/535 (100%)
Query: 21 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80
VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM
Sbjct: 66 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125
Query: 81 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140
DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS
Sbjct: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185
Query: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200
SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC
Sbjct: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245
Query: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260
SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK
Sbjct: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305
Query: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320
YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP
Sbjct: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365
Query: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI
Sbjct: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
Query: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440
LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS
Sbjct: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
Query: 441 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 500
HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT
Sbjct: 486 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 545
Query: 501 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 555
LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES
Sbjct: 546 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600
>gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]
Length = 619
Score = 1080 bits (2793), Expect = 0.0
Identities = 535/554 (96%), Positives = 535/554 (96%), Gaps = 19/554 (3%)
Query: 21 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80
VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM
Sbjct: 66 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125
Query: 81 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140
DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS
Sbjct: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185
Query: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200
SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC
Sbjct: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245
Query: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260
SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK
Sbjct: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305
Query: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320
YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP
Sbjct: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365
Query: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI
Sbjct: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
Query: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440
LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS
Sbjct: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
Query: 441 HFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRRGQPNP 481
HFKNLAANRPPN TYVKLTLLNSMGQEMSKCKTSIRRGQPNP
Sbjct: 486 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 545
Query: 482 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 541
VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES
Sbjct: 546 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 605
Query: 542 KGQQVCRWHALLES 555
KGQQVCRWHALLES
Sbjct: 606 KGQQVCRWHALLES 619
>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
Length = 645
Score = 436 bits (1120), Expect = e-122
Identities = 244/485 (50%), Positives = 327/485 (67%), Gaps = 15/485 (3%)
Query: 74 KIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSP-- 131
K NS+ D +E +SS+S++E + ++ ++SR+ + R + + + E + K+S
Sbjct: 173 KQVNSFGDDEELSTSSDSDEEVIKQFEISVSRSQSFR-SVTSEKGKQTGLEQKPKFSRSL 231
Query: 132 LSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCE- 190
L+ DG A D QR R + L Y +D P S +P E GD+K
Sbjct: 232 LTHGEDGTEVSACEDLDGASQR-RYSENLS------YGEDDHIPAHSQSPCERGDAKHHG 284
Query: 191 FSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP 250
SH +S S + +EGS E +F+++G+E+ +DS+++ SPE+ ++ Q+P
Sbjct: 285 TSHQESSVVQSLRRQSTEGSLEMET-AFNSRGFEDSYATDSSSMWSPEEQDR--TNLQVP 341
Query: 251 KPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQ 310
EP +K G LDV F+Y + QKL VT+ +P +R+G NSWQVH+VLLP KK
Sbjct: 342 SGVS-EPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPGKKH 400
Query: 311 RAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLN 370
R +T+IQRGP PVF E F +E + AVRFRLY +M +E+++GEK+FYL+ L+
Sbjct: 401 RGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLH 460
Query: 371 LQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTG 430
+G+M + ++LEP N S S +S S +S S+STSS QSL HG PE+L+GL YNATTG
Sbjct: 461 PEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTG 520
Query: 431 RLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQ 490
RLS E+IKGSHF+NLA NR P+TY KL LLNS+GQEMS+CKTSIRRGQPNPVYKETFVFQ
Sbjct: 521 RLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQ 580
Query: 491 VALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWH 550
VALFQLSDVTL++SVYN+R+MKRKEMIGWI+LG NSSGEEE +HW EMKE+KGQQ+CRWH
Sbjct: 581 VALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWH 640
Query: 551 ALLES 555
LLES
Sbjct: 641 TLLES 645
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 122 bits (306), Expect = 9e-28
Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)
Query: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
Query: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
Query: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
Query: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
+ +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V
Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
Query: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L
Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Query: 397 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 456
+E ++ + E + ++ L Y+ +L +I+ + L + YVK
Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
Query: 457 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 516
+ LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++
Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 517 IGWISLGLNSSGEEELNHWTE 537
IG + +N+ + H TE
Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 122 bits (306), Expect = 9e-28
Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)
Query: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
Query: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
Query: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
Query: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
+ +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V
Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
Query: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L
Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Query: 397 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 456
+E ++ + E + ++ L Y+ +L +I+ + L + YVK
Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
Query: 457 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 516
+ LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++
Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 517 IGWISLGLNSSGEEELNHWTE 537
IG + +N+ + H TE
Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 122 bits (306), Expect = 9e-28
Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)
Query: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
Query: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
Query: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
Query: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
+ +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V
Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
Query: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L
Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Query: 397 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 456
+E ++ + E + ++ L Y+ +L +I+ + L + YVK
Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
Query: 457 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 516
+ LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++
Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 517 IGWISLGLNSSGEEELNHWTE 537
IG + +N+ + H TE
Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 115 bits (288), Expect = 1e-25
Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 33/297 (11%)
Query: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321
G L+ T YD + + L+V + D+P + TG + V + LLP +K++ +T + R
Sbjct: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTL 292
Query: 322 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
P+F ETF+F V + + N + F +Y R + ++GE I
Sbjct: 293 NPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL---------------- 335
Query: 381 LEPSYNHSGCDSQMSVSEMSCSESTSS---CQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
D+ VS++S + C + E + EI+ L Y T GR++ VI
Sbjct: 336 ----------DNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVI 385
Query: 438 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 497
K + K + + YVK++L+ G+ + K KT+ ++ NPVY E +F + +
Sbjct: 386 KCRNLKAMDITGSSDPYVKVSLMCE-GRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVD 444
Query: 498 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
V+L ++V + + E+IG GL++ G +HW EM + + WH LLE
Sbjct: 445 QVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITHWHPLLE 500
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 111 bits (278), Expect = 2e-24
Identities = 78/300 (26%), Positives = 142/300 (47%), Gaps = 29/300 (9%)
Query: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313
+ EPE G L + DYD Q +L V V ++P + G + V + LLP KK++ +
Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192
Query: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
T + R P F ETF F V + +G + +Y R K I+GE
Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240
Query: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
+ +P+ + D + E + E + +I L Y T G+L
Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287
Query: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
+ +++ + K + + YVK+ L+ + G+ + K KT++++ NP + E+F F++
Sbjct: 288 TVCILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTVKKKTLNPYFNESFSFEIP 346
Query: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Q+ V ++++V + + + E IG I +G N++G EL HW++M + + + +WH+L
Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSL 405
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 111 bits (278), Expect = 2e-24
Identities = 78/300 (26%), Positives = 142/300 (47%), Gaps = 29/300 (9%)
Query: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313
+ EPE G L + DYD Q +L V V ++P + G + V + LLP KK++ +
Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192
Query: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
T + R P F ETF F V + +G + +Y R K I+GE
Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240
Query: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
+ +P+ + D + E + E + +I L Y T G+L
Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287
Query: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
+ +++ + K + + YVK+ L+ + G+ + K KT++++ NP + E+F F++
Sbjct: 288 TVCILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTVKKKTLNPYFNESFSFEIP 346
Query: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Q+ V ++++V + + + E IG I +G N++G EL HW++M + + + +WH+L
Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSL 405
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 110 bits (276), Expect = 3e-24
Identities = 82/323 (25%), Positives = 146/323 (45%), Gaps = 35/323 (10%)
Query: 235 LSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTG 294
+SPE + + S + E + K GTL + +Y+ + + +V + +P +
Sbjct: 134 VSPESLKSSTSLTS------EEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
Query: 295 GNSWQ-VHLVLLPIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHR 352
S + + +LP KK + KT + R P F ETF F + I A+ F + R
Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
Query: 353 MKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSL 411
++ I+GE + L+ + L +GKM + + + + +S+
Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLM---------------NREIIKRNVRKSSGR---- 288
Query: 412 EHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK 471
E+LI L Y +TT L+ V+K H + + YVK+ L ++ + +SK K
Sbjct: 289 -----GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK-KRISKKK 342
Query: 472 TSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEE 531
T +++ PN V+ E FVF + L D+++ V + R E+IG + LG + G
Sbjct: 343 THVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGG 402
Query: 532 LNHWTEMKESKGQQVCRWHALLE 554
HW E+ + +Q+ +WH L +
Sbjct: 403 -EHWKEICDYPRRQIAKWHVLCD 424
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 107 bits (267), Expect = 3e-23
Identities = 85/358 (23%), Positives = 160/358 (44%), Gaps = 36/358 (10%)
Query: 201 SYNKCPSEGSTGHEIESFHNK-GYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEA 259
S +K P S+G I+ K Y E++ S T++ E S+ P PE +
Sbjct: 105 SRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGE--------SKTTSPSSPEEDV 156
Query: 260 KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYN-RTGGNSWQVHLVLLPIKKQRAKTSIQR 318
G+L + DY+ ++ L+VT+ +P + +T G+ + + +LP K+ R KT + R
Sbjct: 157 MLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLR 216
Query: 319 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 377
PVF ETF F + + + + F + R ++ ++GE + L +
Sbjct: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV-------- 268
Query: 378 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
+PS ++ ++ + C S E+ + L Y R++ V+
Sbjct: 269 ----DPS------TGKVQLTRDIIKRNIQKCISRG-----ELQVSLSYQPVAQRMTVVVL 313
Query: 438 KGSHFKNL-AANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQL 496
K H + N YVK+ + + ++K KT +++ NP++ E+F++ + L
Sbjct: 314 KARHLPKMDITGLSGNPYVKVNVYYGR-KRIAKKKTHVKKCTLNPIFNESFIYDIPTDLL 372
Query: 497 SDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
D+++ V + + E++G + LG +S HW E+ ES + V +WH+L E
Sbjct: 373 PDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 105 bits (262), Expect = 1e-22
Identities = 109/435 (25%), Positives = 177/435 (40%), Gaps = 27/435 (6%)
Query: 137 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 192
D S A + N +Q R P + PP G+P S P G D K E +
Sbjct: 259 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 318
Query: 193 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 250
P E TG + + G ED S + S +A ++ Q P
Sbjct: 319 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 373
Query: 251 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 301
P + E EA G L+ + YD L T+ + + G V
Sbjct: 374 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 433
Query: 302 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 357
L LLP K R KT ++ P++ ET ++ + E + +R + + +
Sbjct: 434 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 492
Query: 358 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 417
+GE F L KL + + + LE + S M+ E + +
Sbjct: 493 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 552
Query: 418 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRG 477
+IL+ L+Y+ G L +I+ H + AN + +VKL L MG++ +K KT I++
Sbjct: 553 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK-AKHKTQIKKK 611
Query: 478 QPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTE 537
NP + E F + + L+ +L +SV++ K + IG LG+++ G E L HW E
Sbjct: 612 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ERLKHWYE 670
Query: 538 MKESKGQQVCRWHAL 552
++K +++ RWH L
Sbjct: 671 CLKNKDKKIERWHQL 685
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 105 bits (262), Expect = 1e-22
Identities = 109/435 (25%), Positives = 177/435 (40%), Gaps = 27/435 (6%)
Query: 137 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 192
D S A + N +Q R P + PP G+P S P G D K E +
Sbjct: 255 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 314
Query: 193 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 250
P E TG + + G ED S + S +A ++ Q P
Sbjct: 315 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 369
Query: 251 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 301
P + E EA G L+ + YD L T+ + + G V
Sbjct: 370 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 429
Query: 302 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 357
L LLP K R KT ++ P++ ET ++ + E + +R + + +
Sbjct: 430 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 488
Query: 358 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 417
+GE F L KL + + + LE + S M+ E + +
Sbjct: 489 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 548
Query: 418 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRG 477
+IL+ L+Y+ G L +I+ H + AN + +VKL L MG++ +K KT I++
Sbjct: 549 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK-AKHKTQIKKK 607
Query: 478 QPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTE 537
NP + E F + + L+ +L +SV++ K + IG LG+++ G E L HW E
Sbjct: 608 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ERLKHWYE 666
Query: 538 MKESKGQQVCRWHAL 552
++K +++ RWH L
Sbjct: 667 CLKNKDKKIERWHQL 681
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 105 bits (262), Expect = 1e-22
Identities = 77/294 (26%), Positives = 139/294 (47%), Gaps = 27/294 (9%)
Query: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321
G ++ + YD + + L+V + D+P + G + V + LLP +K + +T + R
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTL 205
Query: 322 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
P F E F F V E + + + ++ R + ++GE VI
Sbjct: 206 NPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGE-----------------VI 247
Query: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440
L+ + S + S+ + ++ +S++ G EI+ L Y T GRL+ VIK
Sbjct: 248 LDNLFEASDLSRETSIWK---DIQYATSESVDLG---EIMFSLCYLPTAGRLTLTVIKCR 301
Query: 441 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 500
+ K + + YVK++LL G+ + K KT+I++ NPVY E +F + + V+
Sbjct: 302 NLKAMDITGYSDPYVKVSLLCD-GRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS 360
Query: 501 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
L++SV + + E+IG +G+ + G +HW EM + + WH+L+E
Sbjct: 361 LLISVMDYDRVGHNEIIGVCRVGITAEGLGR-DHWNEMLAYPRKPIAHWHSLVE 413
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 104 bits (259), Expect = 2e-22
Identities = 87/351 (24%), Positives = 149/351 (42%), Gaps = 31/351 (8%)
Query: 203 NKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG 262
N P G T H+ ES V ++ S M + GS + + G
Sbjct: 81 NTAPVPGQTPHD-ESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEED--EAHEGCSRENLG 137
Query: 263 TLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC- 321
+ + Y+ QE L V + ++P + +G + V + LLP KK + +T ++R
Sbjct: 138 RIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLN 197
Query: 322 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 381
P + ETF F E + + ++ R + +GE L K++L + L
Sbjct: 198 PHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDL 257
Query: 382 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 441
+P CS+ + GS E+L+ L YN + + +IK +
Sbjct: 258 KP-----------------CSDGS--------GSRGELLLSLCYNPSANSIIVNIIKARN 292
Query: 442 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 501
K + + YVK+ L+ + + K KT + NP++ E+F F + +L + T+
Sbjct: 293 LKAMDIGGTSDPYVKVWLMYK-DKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTI 351
Query: 502 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
I++V +K + R ++IG I L SG E+ HW +M Q V +WH L
Sbjct: 352 IITVMDKDKLSRNDVIGKIYLSW-KSGPGEVKHWKDMIARPRQPVAQWHQL 401
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 100 bits (249), Expect = 3e-21
Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 259 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 318
A G + Y +L+V + D+P + G + V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357
Query: 319 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 377
PVF ETF+F+ +E+ + F +Y R + ++G+ + L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403
Query: 378 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
+LE + + E E + E+ L Y T GRL+ +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453
Query: 438 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 497
K S+ K + + YVK +L+ S G+ + K KTSI++ NP Y E VF VA +
Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512
Query: 498 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
+V L ++V + + E+IG +G +++ HW EM + + V WH L+E
Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 100 bits (249), Expect = 3e-21
Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 259 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 318
A G + Y +L+V + D+P + G + V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357
Query: 319 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 377
PVF ETF+F+ +E+ + F +Y R + ++G+ + L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403
Query: 378 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
+LE + + E E + E+ L Y T GRL+ +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453
Query: 438 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 497
K S+ K + + YVK +L+ S G+ + K KTSI++ NP Y E VF VA +
Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512
Query: 498 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
+V L ++V + + E+IG +G +++ HW EM + + V WH L+E
Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 100 bits (249), Expect = 3e-21
Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 259 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 318
A G + Y +L+V + D+P + G + V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357
Query: 319 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 377
PVF ETF+F+ +E+ + F +Y R + ++G+ + L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403
Query: 378 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
+LE + + E E + E+ L Y T GRL+ +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453
Query: 438 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 497
K S+ K + + YVK +L+ S G+ + K KTSI++ NP Y E VF VA +
Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512
Query: 498 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
+V L ++V + + E+IG +G +++ HW EM + + V WH L+E
Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 98.6 bits (244), Expect = 1e-20
Identities = 79/308 (25%), Positives = 135/308 (43%), Gaps = 32/308 (10%)
Query: 250 PKPFDPEPEA----KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLL 305
P P P + + G L + DYD Q +LLV + + + G + V + LL
Sbjct: 94 PAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLL 153
Query: 306 PIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF 364
P K++R +T + R P F ETF F E+ G V +Y R + +GE
Sbjct: 154 PDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLV-MAVYDFDRFSRNDAIGEVRV 212
Query: 365 YLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLL 424
++ ++L PV + E + +I L
Sbjct: 213 PMSSVDL----GRPV--------------------QAWRELQAAPREEQEKLGDICFSLR 248
Query: 425 YNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYK 484
Y T G+L+ V++ + K + + YVK+ LL G+++ K KT+I++ NP Y
Sbjct: 249 YVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG-GKKVRKKKTTIKKNTLNPYYN 307
Query: 485 ETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQ 544
E F F+V Q+ V + L+V + + + E IG +++G ++G L HW +M + +
Sbjct: 308 EAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRR 366
Query: 545 QVCRWHAL 552
+ +WH+L
Sbjct: 367 PIAQWHSL 374
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Query: 393 QMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPN 452
Q V E+ + S Q + + + L Y+ +G+L +++ L +
Sbjct: 86 QPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSD 145
Query: 453 TYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMK 512
YV++ LL + + +T + R NP + ETF F+V +L L+++VY+
Sbjct: 146 PYVRVYLLPD---KRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFS 202
Query: 513 RKEMIGWISLGLNS 526
R + IG + + ++S
Sbjct: 203 RNDAIGEVRVPMSS 216
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 93.6 bits (231), Expect = 4e-19
Identities = 74/300 (24%), Positives = 133/300 (44%), Gaps = 39/300 (13%)
Query: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321
G L+ YD ++L+V + ++P + +G + V + LLP +K + +T + R
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
Query: 322 -PVFTETFKF----NHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF--YLTKLNLQGK 374
PVF E F F N +E+ + F +Y R + ++G+ + +L + +
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKL-----HFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRE 336
Query: 375 MSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSA 434
L +E N ++ + E++ L Y T GRL+
Sbjct: 337 CILWKDIEYVTN-------------------------DNVDLGELMFSLCYLPTAGRLTI 371
Query: 435 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALF 494
+IK + K + + YVK++L+ G+ + K KTS +R NPVY E VF V
Sbjct: 372 TIIKARNLKAMDITGASDPYVKVSLMCD-GRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430
Query: 495 QLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
+ + L ++V + + E+IG +G N + +HW+EM + + WH+L+E
Sbjct: 431 NIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 91.7 bits (226), Expect = 2e-18
Identities = 92/361 (25%), Positives = 156/361 (43%), Gaps = 35/361 (9%)
Query: 206 PSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP-KPFDPEPEAK---- 260
P+ G S + +EDV A S S S ++ P KP + EP+A
Sbjct: 62 PAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYES 121
Query: 261 -----YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLP----IKKQR 311
GTLD + YD + L T+T + + G V L LLP K R
Sbjct: 122 DDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLR 181
Query: 312 AKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL 371
KT ++ P + ET + + E + +R + + + + +GE L KL
Sbjct: 182 TKT-LRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKP 240
Query: 372 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 431
+ + LE Q+ V + + +SLE ILI L Y++
Sbjct: 241 NHTKTFNICLE---------KQLPVDK-------TEDKSLEERG--RILISLKYSSQKQG 282
Query: 432 LSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQV 491
L +++ +H + AN + YVK T L + SK KT++++ NP + E F +++
Sbjct: 283 LLVGIVRCAHLAAMDANGYSDPYVK-TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEI 341
Query: 492 ALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHA 551
L+ +L ++V++ K + IG + LG+++ G E L HW + ++K +++ RWH
Sbjct: 342 KHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKG-ERLKHWFDCLKNKDKRIERWHT 400
Query: 552 L 552
L
Sbjct: 401 L 401
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 88.2 bits (217), Expect = 2e-17
Identities = 84/338 (24%), Positives = 142/338 (42%), Gaps = 43/338 (12%)
Query: 228 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKY--GTLDVTFDYDSQEQKLLVTVTAVT 285
P D P S +S + D E +KY G L + YD L V V
Sbjct: 150 PDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEAR 209
Query: 286 DIPT-YNRTGGNSWQVH------LVLLPIKKQRAKTSIQRGPC-PVFTE--TFKFNHVES 335
D+P + G H + LLP +K +T ++R PVF E TF+ +E+
Sbjct: 210 DLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEA 269
Query: 336 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQM 394
+ + + + + ++G+ L +++L +G ++ S N
Sbjct: 270 Q---RRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNE------- 319
Query: 395 SVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTY 454
+E G E+L+ L Y + GRL+ +VI+ ++ + +
Sbjct: 320 ----------------VELG---ELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF 360
Query: 455 VKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRK 514
VK+ L++ + +K KTS RG +P Y E+F F+V +L + +L+ +V+
Sbjct: 361 VKIQLVHGLKLVKTK-KTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSN 419
Query: 515 EMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
+ IG I +G SSG E NHW M + V +WH+L
Sbjct: 420 DFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 87.8 bits (216), Expect = 2e-17
Identities = 72/291 (24%), Positives = 129/291 (44%), Gaps = 26/291 (8%)
Query: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321
G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR
Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213
Query: 322 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 381
+F + ++ + ++RF ++G+ ++ G L+ L+L L
Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265
Query: 382 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 441
+P Q ++ +V EIL+ L Y T RL+ V+K +
Sbjct: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKAKN 309
Query: 442 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 501
+ +VK+ LL G++MSK KT+++R PNPV+ E +F V L D++L
Sbjct: 310 LIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSL 368
Query: 502 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
++V S R + +G + +G ++SG HW +M + + V WHA+
Sbjct: 369 RVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWHAV 418
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 83.2 bits (204), Expect = 6e-16
Identities = 80/333 (24%), Positives = 137/333 (41%), Gaps = 18/333 (5%)
Query: 228 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI 287
P+ +PED + S +D + GTL+ YD L ++ +
Sbjct: 64 PAALLGATTPEDGAEVDS-------YDSDDATALGTLEFDLLYDRASCTLHCSILRAKGL 116
Query: 288 PTYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVR 344
+ G V L LLP K + KT QR PV+ E ++ + + I + +R
Sbjct: 117 KPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLR 176
Query: 345 FRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSES 404
+ ++ + +GE L +L K + LE + S MS + S
Sbjct: 177 IAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLAS-PSSMSAALRGISCY 235
Query: 405 TSSCQSLEHGSV-----PEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTL 459
+ E G IL+ L Y++ L +++ +H + N + YVK T
Sbjct: 236 LKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVK-TY 294
Query: 460 LNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGW 519
L + SK KT +++ NP + E F +++ L L+ TL ++V++ K + IG
Sbjct: 295 LRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGG 354
Query: 520 ISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
+SLG + GE HW++ + + RWH L
Sbjct: 355 VSLGPGARGEAR-KHWSDCLQQPDAALERWHTL 386
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 82.8 bits (203), Expect = 8e-16
Identities = 80/301 (26%), Positives = 133/301 (44%), Gaps = 34/301 (11%)
Query: 257 PEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSI 316
P+ G L + +Y+ + ++LLV + + + T S V L LLP +++ ++
Sbjct: 144 PDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC--SPLVKLYLLPDERRFLQSKT 201
Query: 317 QRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 375
+R P F E F F V S+ I ++F +Y V R +K +++G+ +F L L G
Sbjct: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDC 260
Query: 376 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGS-VPEILIGLLYNATTGRLSA 434
+ + +SLE S ++ L YN RL+
Sbjct: 261 RRVIWRD-----------------------LEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
Query: 435 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK-TSIRRGQPNPVYKETFVFQVAL 493
V++ + + +VK++L+N + KCK TS G NPVY ETF F+
Sbjct: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNH--NKFVKCKKTSAVLGSINPVYNETFSFKADA 355
Query: 494 FQLSDVTLILSVYNKRSMKRKEMIGWISLG--LNSSGEEELNHWTEMKESKGQQVCRWHA 551
+L +L L+V + + +G + +G + + G EL HW EM + V RWHA
Sbjct: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRG-RELEHWDEMLSKPKELVKRWHA 414
Query: 552 L 552
L
Sbjct: 415 L 415
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 80.9 bits (198), Expect = 3e-15
Identities = 90/337 (26%), Positives = 142/337 (42%), Gaps = 42/337 (12%)
Query: 235 LSPEDMSAQGSSSQLPKPFDPEPEAK------YGTLDVTFDYDSQEQKLLVTVTAVTDIP 288
L P SA S+ QL DPEPE GTL+ T +++ L T +
Sbjct: 109 LRPAAASAVRSAPQLQP--DPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 166
Query: 289 TYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGP-CPVFTETFKFNH----------VES 335
+G V LLP K + +T RG PV+ ET ++ + S
Sbjct: 167 PL-ASGSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRS 225
Query: 336 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMS 395
++ G+ AV R V R + +GE L KL S + LE +
Sbjct: 226 DLGGHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDICLE----------KRR 275
Query: 396 VSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYV 455
+ E+ + C +L+ L Y++ G L V++ +H + AN + +V
Sbjct: 276 LEEVETEVAWEECG--------HVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFV 327
Query: 456 KLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKE 515
+L L + G++ SK KTS+ R NP + E F + +L+ TL++SV++ +
Sbjct: 328 RLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADD 386
Query: 516 MIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
IG + LG ++SG E L HW E ++ WH L
Sbjct: 387 FIGGVQLGSHASG-ERLRHWLECLGHSDHRLKLWHPL 422
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 79.3 bits (194), Expect = 8e-15
Identities = 73/300 (24%), Positives = 134/300 (44%), Gaps = 37/300 (12%)
Query: 255 PEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKK-QRAK 313
P ++G L ++ ++D Q++ V + D+ R GG V + + R +
Sbjct: 112 PGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL----RPGGTVDPYARVSVSTQAGHRHE 167
Query: 314 TSIQRGP-CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
T + RG CPVF ET F+ ++E+ G ++ +L+ R + +GE L ++LQ
Sbjct: 168 TKVHRGTLCPVFDETCCFHIPQAELPGA-TLQVQLFNFKRFSGHEPLGELRLPLGTVDLQ 226
Query: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
+ +L P + + V E+ L Y ++GRL
Sbjct: 227 HVLEHWYLLGPP------------------------AATQPEQVGELCFSLRYVPSSGRL 262
Query: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
+ V++ + A YVK+ L+ + ++ K KT+ ++G P + E F F V
Sbjct: 263 TVVVLEARGLRPGLAE----PYVKVQLMLNQ-RKWKKRKTATKKGTAAPYFNEAFTFLVP 317
Query: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Q+ +V L+L+V+++ R E +G + LG +SG + L HW +M + + + H L
Sbjct: 318 FSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376
>gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/181 (27%), Positives = 86/181 (47%), Gaps = 15/181 (8%)
Query: 372 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 431
Q + +P +P +N S S+ E+ + C +L+ L Y++ G
Sbjct: 277 QRQPRVPSAPDPKHN-----SARSMEEVETEVAWEECG--------HVLLSLCYSSQQGG 323
Query: 432 LSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQV 491
L V++ +H + AN + +V+L L + G++ SK KTS+ R NP + E F +
Sbjct: 324 LLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSG 382
Query: 492 ALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHA 551
+L+ TL++SV++ + IG + LG ++SG E L HW E ++ WH
Sbjct: 383 PREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASG-ERLRHWLECLGHSDHRLELWHP 441
Query: 552 L 552
L
Sbjct: 442 L 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,838,517
Number of Sequences: 37866
Number of extensions: 1094750
Number of successful extensions: 2849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 2674
Number of HSP's gapped (non-prelim): 163
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.