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Search of human proteins with 14277685
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14277685 protocadherin gamma subfamily C, 5 isoform 2
precursor [Homo sapiens]
(878 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 1750 0.0
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 1634 0.0
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 678 0.0
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 678 0.0
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 664 0.0
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 664 0.0
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 629 e-180
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 629 e-180
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 612 e-175
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 612 e-175
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 610 e-174
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 610 e-174
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 608 e-174
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 608 e-174
gi|11036656 protocadherin beta 7 precursor [Homo sapiens] 608 e-174
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 604 e-172
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs... 604 e-172
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 600 e-171
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs... 600 e-171
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 599 e-171
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 599 e-171
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs... 599 e-171
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 599 e-171
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs... 598 e-171
gi|14196462 protocadherin gamma subfamily A, 2 isoform 2 precurs... 598 e-171
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 595 e-170
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 595 e-170
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 595 e-170
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 595 e-170
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 594 e-169
>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
[Homo sapiens]
Length = 878
Score = 1750 bits (4532), Expect = 0.0
Identities = 878/878 (100%), Positives = 878/878 (100%)
Query: 1 MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL
Sbjct: 1 MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
Query: 61 SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE
Sbjct: 61 SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL
Sbjct: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP
Sbjct: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420
ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY
Sbjct: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420
Query: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480
IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD
Sbjct: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480
Query: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540
PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG
Sbjct: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540
Query: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600
SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG
Sbjct: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600
Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA
Sbjct: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
Query: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720
TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN
Sbjct: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720
Query: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780
ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP
Sbjct: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780
Query: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQVRGSAPPRATPGGGTGEAAR 840
ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQVRGSAPPRATPGGGTGEAAR
Sbjct: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQVRGSAPPRATPGGGTGEAAR 840
Query: 841 PHKGLNLHPLLSGRLGRWLRSTRFSGSLDRLRETRVAD 878
PHKGLNLHPLLSGRLGRWLRSTRFSGSLDRLRETRVAD
Sbjct: 841 PHKGLNLHPLLSGRLGRWLRSTRFSGSLDRLRETRVAD 878
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 1634 bits (4231), Expect = 0.0
Identities = 823/827 (99%), Positives = 823/827 (99%), Gaps = 3/827 (0%)
Query: 1 MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL
Sbjct: 1 MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
Query: 61 SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE
Sbjct: 61 SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL
Sbjct: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP
Sbjct: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420
ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY
Sbjct: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420
Query: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480
IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD
Sbjct: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480
Query: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540
PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG
Sbjct: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540
Query: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600
SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG
Sbjct: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600
Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA
Sbjct: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
Query: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720
TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN
Sbjct: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720
Query: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780
ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP
Sbjct: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780
Query: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQVRGSAPP 827
ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQ APP
Sbjct: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQ---QAPP 824
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 678 bits (1750), Expect = 0.0
Identities = 365/746 (48%), Positives = 492/746 (65%), Gaps = 13/746 (1%)
Query: 25 GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84
G+V GQ+RY V EES+ GT VGNVAQD L L +RRLQ+ E N R+F + L SGAL
Sbjct: 25 GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
Query: 85 AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144
+ IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F + ++ I E
Sbjct: 85 LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
Query: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204
+A G RFPL+ AQD DVG+N++S Y LS N HF+L+VK DG PEL+LE+ LDRE
Sbjct: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
Query: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264
Q+ ++LVLTAVDGG P RSGT + V VLD+NDNAP FQ S R+ + E+AP G +L++L
Sbjct: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
Query: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324
NA+DPD G +G + + F HT + VRNLF L P++G + +LGP+DFE +YE RARD
Sbjct: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
Query: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384
G PAME HC ++VD+ DVNDNAP + + S + ES GTVV L +V+D DSG NG+
Sbjct: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
Query: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443
VSL I LPF +K + N +SL+T+ PLDREA S Y I + ASDAG+P L H TI LN
Sbjct: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
Query: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503
ISDVNDN P F Q+ + ++ EN PG LLC++AASDPD+G NA ++YS++ + + A
Sbjct: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
Query: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563
SSF+ +NP+ G + A R+FDYE Q LQ V RD G+PPL + ++ +FVLD NDNAPA
Sbjct: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
Query: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623
VL PR PQ LP S G L+TKVTAVD D+G+NAW+SY LL ++ P LF VS
Sbjct: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623
Query: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683
+ GEVRTA + D Q++V++V+D+G P LS++ T+L+ LE++ +P +
Sbjct: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682
Query: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736
S LTLYL V+L + +S +F L +KCL+G A G G C RR++
Sbjct: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742
Query: 737 PSPDFYKQSSPNLQVSSDGTLKYMEV 762
P +Q+ SD +K+++V
Sbjct: 743 LPP---SNGILRIQLGSDDPIKFVDV 765
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 678 bits (1750), Expect = 0.0
Identities = 365/746 (48%), Positives = 492/746 (65%), Gaps = 13/746 (1%)
Query: 25 GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84
G+V GQ+RY V EES+ GT VGNVAQD L L +RRLQ+ E N R+F + L SGAL
Sbjct: 25 GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
Query: 85 AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144
+ IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F + ++ I E
Sbjct: 85 LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
Query: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204
+A G RFPL+ AQD DVG+N++S Y LS N HF+L+VK DG PEL+LE+ LDRE
Sbjct: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
Query: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264
Q+ ++LVLTAVDGG P RSGT + V VLD+NDNAP FQ S R+ + E+AP G +L++L
Sbjct: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
Query: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324
NA+DPD G +G + + F HT + VRNLF L P++G + +LGP+DFE +YE RARD
Sbjct: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
Query: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384
G PAME HC ++VD+ DVNDNAP + + S + ES GTVV L +V+D DSG NG+
Sbjct: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
Query: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443
VSL I LPF +K + N +SL+T+ PLDREA S Y I + ASDAG+P L H TI LN
Sbjct: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
Query: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503
ISDVNDN P F Q+ + ++ EN PG LLC++AASDPD+G NA ++YS++ + + A
Sbjct: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
Query: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563
SSF+ +NP+ G + A R+FDYE Q LQ V RD G+PPL + ++ +FVLD NDNAPA
Sbjct: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
Query: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623
VL PR PQ LP S G L+TKVTAVD D+G+NAW+SY LL ++ P LF VS
Sbjct: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623
Query: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683
+ GEVRTA + D Q++V++V+D+G P LS++ T+L+ LE++ +P +
Sbjct: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682
Query: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736
S LTLYL V+L + +S +F L +KCL+G A G G C RR++
Sbjct: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742
Query: 737 PSPDFYKQSSPNLQVSSDGTLKYMEV 762
P +Q+ SD +K+++V
Sbjct: 743 LPP---SNGILRIQLGSDDPIKFVDV 765
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 664 bits (1712), Expect = 0.0
Identities = 355/783 (45%), Positives = 505/783 (64%), Gaps = 10/783 (1%)
Query: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72
+L +L L G + QLRYSV EE PG LVGNVA+ LGL++ L L++ +
Sbjct: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
Query: 73 RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
RY L L SGAL VN++IDRE+LC CLL ++V+ +P+ + VEVEILD+NDNSP
Sbjct: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
F P ++++SES A GARF ++SAQDPDVG N+V Y LSP+ HF L++K L++
Sbjct: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
ELVL + LDRE A H LVLTAVDGG PARSGT ISV VLD NDN+P F S RV +
Sbjct: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
E++P GTL+++LNA+DPDEG+NG+L YS +TS+ R LF +D S+G + V+G +D+EE
Sbjct: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
+ Y+I+ +A D+G M GHC + VD+ DVNDNAPEV+L L +PV E+ T+V +
Sbjct: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432
+V D+DSG N +VSL + LPF++ N Y+L+ S PLDRE + Y I + A+D G P
Sbjct: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447
Query: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492
L T+++ ISD+NDN P F + Y+ YI EN PG LLCTV A+DPD +NA +TYS
Sbjct: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507
Query: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552
++ ++QG P +S+V +N G ++A +FDYE + + V +D GSPPL + + +V
Sbjct: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567
Query: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
+V+D ND+AP +L+P +A + +PR+AP G LVTKV A+D+D+G NAWL Y L Q
Sbjct: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626
Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
++ LF V HTGE+RT R + ++ T + V+VRDNG+PSLS++ + + + D +
Sbjct: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686
Query: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730
+P + + P S++TLYLI+AL+TVS + L+T LS KC + A G GG C
Sbjct: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746
Query: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786
R+ SP+ + YKQ++ N+ LK ++EV + ++++CY+ C + S
Sbjct: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805
Query: 787 FTF 789
F F
Sbjct: 806 FMF 808
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 664 bits (1712), Expect = 0.0
Identities = 355/783 (45%), Positives = 505/783 (64%), Gaps = 10/783 (1%)
Query: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72
+L +L L G + QLRYSV EE PG LVGNVA+ LGL++ L L++ +
Sbjct: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
Query: 73 RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
RY L L SGAL VN++IDRE+LC CLL ++V+ +P+ + VEVEILD+NDNSP
Sbjct: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
F P ++++SES A GARF ++SAQDPDVG N+V Y LSP+ HF L++K L++
Sbjct: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
ELVL + LDRE A H LVLTAVDGG PARSGT ISV VLD NDN+P F S RV +
Sbjct: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
E++P GTL+++LNA+DPDEG+NG+L YS +TS+ R LF +D S+G + V+G +D+EE
Sbjct: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
+ Y+I+ +A D+G M GHC + VD+ DVNDNAPEV+L L +PV E+ T+V +
Sbjct: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432
+V D+DSG N +VSL + LPF++ N Y+L+ S PLDRE + Y I + A+D G P
Sbjct: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447
Query: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492
L T+++ ISD+NDN P F + Y+ YI EN PG LLCTV A+DPD +NA +TYS
Sbjct: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507
Query: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552
++ ++QG P +S+V +N G ++A +FDYE + + V +D GSPPL + + +V
Sbjct: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567
Query: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
+V+D ND+AP +L+P +A + +PR+AP G LVTKV A+D+D+G NAWL Y L Q
Sbjct: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626
Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
++ LF V HTGE+RT R + ++ T + V+VRDNG+PSLS++ + + + D +
Sbjct: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686
Query: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730
+P + + P S++TLYLI+AL+TVS + L+T LS KC + A G GG C
Sbjct: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746
Query: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786
R+ SP+ + YKQ++ N+ LK ++EV + ++++CY+ C + S
Sbjct: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805
Query: 787 FTF 789
F F
Sbjct: 806 FMF 808
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 629 bits (1622), Expect = e-180
Identities = 358/833 (42%), Positives = 498/833 (59%), Gaps = 62/833 (7%)
Query: 27 VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
V QL Y+V EE E GT VGN+A+DLGL +T L +R Q Y L+L +G L V
Sbjct: 16 VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75
Query: 87 NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
N+KIDRE +C S SC+L ++V E+PLEL +VE+E+LD+NDN PSF P+ + ISESA
Sbjct: 76 NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135
Query: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
G RFPL+SA DPDVGTN++ Y ++PNS+FSL+V+T DG F ELVLE+ LDRE QA
Sbjct: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195
Query: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247
H+ VLTAVDGG R+GT L+++ VLD NDN P F V
Sbjct: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255
Query: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307
V +PEN+P GTL+++LNATDPDEG NG++ YSF H S R LFGL P +G + V G
Sbjct: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315
Query: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367
+D+EES Y+++ +A+D G A+ HC + V V D NDNAPE+ +++ V E GT
Sbjct: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375
Query: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426
VV LF+V DRDS NG+V ++ D+PF++K S +N+Y+++T PLDREA Y + ++A
Sbjct: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435
Query: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486
D G P+L +I++ +SDVNDNAPRF+Q +Y Y+ EN PG+ + V+A+D D G N
Sbjct: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495
Query: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545
A+L YSI+ Q+QG ++V +N E+G ++A R+FDYE L+ V RD+GSP L
Sbjct: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555
Query: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603
N ++++ ++D+NDNAPA++ P P + P R LPRSA PG L+T+V AVDAD G NA
Sbjct: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614
Query: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661
L+YS++ + LF + TGE+RTAR + D ++V+ VRD+G P LSSTAT
Sbjct: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673
Query: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709
+++ L D E P RS DLTL LI+AL +VS + L+
Sbjct: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733
Query: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753
L+ +C + GGG CC RQ +S L SS
Sbjct: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793
Query: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799
+ +V + + +Q++CY+ C +P S +D FL+P S + T
Sbjct: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRST 846
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 629 bits (1622), Expect = e-180
Identities = 358/833 (42%), Positives = 498/833 (59%), Gaps = 62/833 (7%)
Query: 27 VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
V QL Y+V EE E GT VGN+A+DLGL +T L +R Q Y L+L +G L V
Sbjct: 16 VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75
Query: 87 NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
N+KIDRE +C S SC+L ++V E+PLEL +VE+E+LD+NDN PSF P+ + ISESA
Sbjct: 76 NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135
Query: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
G RFPL+SA DPDVGTN++ Y ++PNS+FSL+V+T DG F ELVLE+ LDRE QA
Sbjct: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195
Query: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247
H+ VLTAVDGG R+GT L+++ VLD NDN P F V
Sbjct: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255
Query: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307
V +PEN+P GTL+++LNATDPDEG NG++ YSF H S R LFGL P +G + V G
Sbjct: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315
Query: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367
+D+EES Y+++ +A+D G A+ HC + V V D NDNAPE+ +++ V E GT
Sbjct: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375
Query: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426
VV LF+V DRDS NG+V ++ D+PF++K S +N+Y+++T PLDREA Y + ++A
Sbjct: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435
Query: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486
D G P+L +I++ +SDVNDNAPRF+Q +Y Y+ EN PG+ + V+A+D D G N
Sbjct: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495
Query: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545
A+L YSI+ Q+QG ++V +N E+G ++A R+FDYE L+ V RD+GSP L
Sbjct: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555
Query: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603
N ++++ ++D+NDNAPA++ P P + P R LPRSA PG L+T+V AVDAD G NA
Sbjct: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614
Query: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661
L+YS++ + LF + TGE+RTAR + D ++V+ VRD+G P LSSTAT
Sbjct: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673
Query: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709
+++ L D E P RS DLTL LI+AL +VS + L+
Sbjct: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733
Query: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753
L+ +C + GGG CC RQ +S L SS
Sbjct: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793
Query: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799
+ +V + + +Q++CY+ C +P S +D FL+P S + T
Sbjct: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRST 846
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 612 bits (1578), Expect = e-175
Identities = 335/703 (47%), Positives = 461/703 (65%), Gaps = 7/703 (0%)
Query: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
+LC+ G+ + Q+RYSV EE+E G+ VGN+++DLGL+ +L R +++ S +
Sbjct: 16 LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75
Query: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
F+++ SG+L +IDRE LC +SC L ++++ E L++ VEVEI+D+NDN+PSF
Sbjct: 76 FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135
Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
E E+++SE A GARF L +A+DPDVG N++ Y LSPN++FSL ++ DG PEL
Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195
Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
VLE LDRE +A H L+LTA+DGG P R G I V+VLD+ND+ P F SV RV +PEN
Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255
Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
GT +L +NATDPDEG NG++ YSF + S+A +F LD +G + V G +DFE+ R
Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRNMESKA-SEIFQLDSQTGEVQVRGSLDFEKYR 314
Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
FYE+ + +D G + + + V DVNDNAPE+ + S N +LE++P GTV+ L NV
Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372
Query: 375 RDRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
+D+DSG NG+VS I LPF++ K N+Y L+TS+ LDRE Y I L A+D GSP
Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432
Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
L + LN++D NDN P F Y+AYI EN P G+ + +V A DPD+ NA +TYS+
Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492
Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
+ VQG P SS+V +N G ++A ++FDYE + L++ V RDSG PPL +N SL +F
Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552
Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
VLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D+G NAWLSY LL +
Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLL-K 611
Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T T+ + + D PE
Sbjct: 612 ASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPE 671
Query: 673 EMPKSSDF-LIHPPERSDLTLYLIVALATVSLLSLVTFTFLSA 714
+ + E SDL+LYL+VA+A VS + LV L A
Sbjct: 672 VLADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLA 714
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 612 bits (1578), Expect = e-175
Identities = 335/703 (47%), Positives = 461/703 (65%), Gaps = 7/703 (0%)
Query: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
+LC+ G+ + Q+RYSV EE+E G+ VGN+++DLGL+ +L R +++ S +
Sbjct: 16 LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75
Query: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
F+++ SG+L +IDRE LC +SC L ++++ E L++ VEVEI+D+NDN+PSF
Sbjct: 76 FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135
Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
E E+++SE A GARF L +A+DPDVG N++ Y LSPN++FSL ++ DG PEL
Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195
Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
VLE LDRE +A H L+LTA+DGG P R G I V+VLD+ND+ P F SV RV +PEN
Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255
Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
GT +L +NATDPDEG NG++ YSF + S+A +F LD +G + V G +DFE+ R
Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRNMESKA-SEIFQLDSQTGEVQVRGSLDFEKYR 314
Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
FYE+ + +D G + + + V DVNDNAPE+ + S N +LE++P GTV+ L NV
Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372
Query: 375 RDRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
+D+DSG NG+VS I LPF++ K N+Y L+TS+ LDRE Y I L A+D GSP
Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432
Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
L + LN++D NDN P F Y+AYI EN P G+ + +V A DPD+ NA +TYS+
Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492
Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
+ VQG P SS+V +N G ++A ++FDYE + L++ V RDSG PPL +N SL +F
Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552
Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
VLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D+G NAWLSY LL +
Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLL-K 611
Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T T+ + + D PE
Sbjct: 612 ASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPE 671
Query: 673 EMPKSSDF-LIHPPERSDLTLYLIVALATVSLLSLVTFTFLSA 714
+ + E SDL+LYL+VA+A VS + LV L A
Sbjct: 672 VLADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLA 714
>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
[Homo sapiens]
Length = 813
Score = 610 bits (1574), Expect = e-174
Identities = 335/682 (49%), Positives = 447/682 (65%), Gaps = 7/682 (1%)
Query: 28 SGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVN 87
SGQ+RYS+ EE + G+ VGN+A+DLGL+ +L R +++ S + F+L+ SG+L
Sbjct: 28 SGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTA 87
Query: 88 QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147
+IDRE LC S C++ ++ E+ +++ VEVEI+D+NDN P F E +++++E+AA
Sbjct: 88 GRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147
Query: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
+G R L A+D DVG N++ Y LS N HFSL+V + DG+ +PELVLEQ LDRE +
Sbjct: 148 AGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKETV 207
Query: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNAT 267
H L+LTA+DGG P SGTT I V VLD NDNAP F S V +PEN P+GT LL L AT
Sbjct: 208 HDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTAT 267
Query: 268 DPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQ 327
DPDEG NG+L YSF + E + F LD + G I L +D+EESRFY + A+D G
Sbjct: 268 DPDEGINGKLTYSFRNE-EEKISETFQLDSNLGEISTLQSLDYEESRFYLMEVVAQDGG- 325
Query: 328 PAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSL 387
A+ + V V DVNDNAPEV+L SL + + E GTV+ LF+V D DSG NGE++
Sbjct: 326 -ALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGTVIALFSVHDGDSGENGEIAC 384
Query: 388 DISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISD 446
I +LPF+++ S +N+Y LLT++ LDRE TS Y I L D G+P L I L ++D
Sbjct: 385 SIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLSTESHIPLKVAD 444
Query: 447 VNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSF 506
VNDN P F Q Y+ + EN P G + +V A DPD+GDNAR+TYS+ + QGAP SS+
Sbjct: 445 VNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSLAEDTFQGAPLSSY 504
Query: 507 VYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLH 566
V +N + G ++A R+FDYE L+ LQ+ V DSG+PPL +N SL +FVLD+NDN P +L+
Sbjct: 505 VSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY 564
Query: 567 PRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHT 625
P + S L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V HT
Sbjct: 565 PALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLL-KASEPGLFAVGLHT 623
Query: 626 GEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH-P 684
GEVRTARALL+ D+ Q +VV V D+G P LS+T TV + + D P+ +
Sbjct: 624 GEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVADRIPDILADLGSIKTPID 683
Query: 685 PERSDLTLYLIVALATVSLLSL 706
PE DLTLYL+VA+A VS + L
Sbjct: 684 PEDLDLTLYLVVAVAAVSCVFL 705
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 610 bits (1574), Expect = e-174
Identities = 335/682 (49%), Positives = 447/682 (65%), Gaps = 7/682 (1%)
Query: 28 SGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVN 87
SGQ+RYS+ EE + G+ VGN+A+DLGL+ +L R +++ S + F+L+ SG+L
Sbjct: 28 SGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTA 87
Query: 88 QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147
+IDRE LC S C++ ++ E+ +++ VEVEI+D+NDN P F E +++++E+AA
Sbjct: 88 GRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147
Query: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
+G R L A+D DVG N++ Y LS N HFSL+V + DG+ +PELVLEQ LDRE +
Sbjct: 148 AGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKETV 207
Query: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNAT 267
H L+LTA+DGG P SGTT I V VLD NDNAP F S V +PEN P+GT LL L AT
Sbjct: 208 HDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTAT 267
Query: 268 DPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQ 327
DPDEG NG+L YSF + E + F LD + G I L +D+EESRFY + A+D G
Sbjct: 268 DPDEGINGKLTYSFRNE-EEKISETFQLDSNLGEISTLQSLDYEESRFYLMEVVAQDGG- 325
Query: 328 PAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSL 387
A+ + V V DVNDNAPEV+L SL + + E GTV+ LF+V D DSG NGE++
Sbjct: 326 -ALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGTVIALFSVHDGDSGENGEIAC 384
Query: 388 DISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISD 446
I +LPF+++ S +N+Y LLT++ LDRE TS Y I L D G+P L I L ++D
Sbjct: 385 SIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLSTESHIPLKVAD 444
Query: 447 VNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSF 506
VNDN P F Q Y+ + EN P G + +V A DPD+GDNAR+TYS+ + QGAP SS+
Sbjct: 445 VNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSLAEDTFQGAPLSSY 504
Query: 507 VYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLH 566
V +N + G ++A R+FDYE L+ LQ+ V DSG+PPL +N SL +FVLD+NDN P +L+
Sbjct: 505 VSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY 564
Query: 567 PRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHT 625
P + S L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V HT
Sbjct: 565 PALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLL-KASEPGLFAVGLHT 623
Query: 626 GEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH-P 684
GEVRTARALL+ D+ Q +VV V D+G P LS+T TV + + D P+ +
Sbjct: 624 GEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVADRIPDILADLGSIKTPID 683
Query: 685 PERSDLTLYLIVALATVSLLSL 706
PE DLTLYL+VA+A VS + L
Sbjct: 684 PEDLDLTLYLVVAVAAVSCVFL 705
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 608 bits (1569), Expect = e-174
Identities = 332/693 (47%), Positives = 450/693 (64%), Gaps = 17/693 (2%)
Query: 30 QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK 89
Q+ YSV EE E G++VGN+A+DLGL +L R +++ S + F+L+ SG L +
Sbjct: 30 QILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGR 89
Query: 90 IDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
IDRE LC S +C+ ++++ E ++++RVEVEI+D+NDN PSF T +RE++++E+ G
Sbjct: 90 IDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPG 149
Query: 150 ARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQ 209
ARFPL A DPDVG N++ Y L+ N +FSL+V++ DG +PELVLE+ LDRE +A H
Sbjct: 150 ARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHH 209
Query: 210 LVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDP 269
LVLTA DGG P RSGT I +I++D NDNAP F V + EN P+GT LL + ATDP
Sbjct: 210 LVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDP 269
Query: 270 DEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPA 329
DEG NG + YSF + + LF L+ SG I +LG +D+E+S FY+I A D P
Sbjct: 270 DEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHD--GPG 326
Query: 330 MEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDI 389
+ + V V D NDNAPEV + SL + V ES+ GTV+ LFNV D DSG NG V+ I
Sbjct: 327 LRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSI 386
Query: 390 SPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVN 448
+LPF + K N+Y LLT + LDRE S Y I + A+D G+P L I L + D+N
Sbjct: 387 PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDIN 446
Query: 449 DNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVY 508
DN P F Y+AYI EN P G+ + ++ A DPD+GDNAR+TYS+ + QGAP SS+V
Sbjct: 447 DNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVS 506
Query: 509 VNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPR 568
+N G ++A +FDYE + LQ+++ DSG PPL +N SL +FVLD+NDN P +L+P
Sbjct: 507 INSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPT 566
Query: 569 -PDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGE 627
P + + PRSA G LVTKV AVD D+G NAWLSYSLL +S+ PGLF V HTGE
Sbjct: 567 FPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLL-KSSEPGLFAVGLHTGE 625
Query: 628 VRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------EMPKSSDFL 681
VRTARALL+ D+ Q++VV+V+D+G P LS+T T+ + + D P+ + S+D
Sbjct: 626 VRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSAD-- 683
Query: 682 IHPPERSDLTLYLIVALATVSLLSLVTFTFLSA 714
P+ S LTLYL+VA+A VS + L T L A
Sbjct: 684 ---PDDSGLTLYLVVAVAAVSCVFLAFVTVLLA 713
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 608 bits (1569), Expect = e-174
Identities = 332/693 (47%), Positives = 450/693 (64%), Gaps = 17/693 (2%)
Query: 30 QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK 89
Q+ YSV EE E G++VGN+A+DLGL +L R +++ S + F+L+ SG L +
Sbjct: 30 QILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGR 89
Query: 90 IDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
IDRE LC S +C+ ++++ E ++++RVEVEI+D+NDN PSF T +RE++++E+ G
Sbjct: 90 IDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPG 149
Query: 150 ARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQ 209
ARFPL A DPDVG N++ Y L+ N +FSL+V++ DG +PELVLE+ LDRE +A H
Sbjct: 150 ARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHH 209
Query: 210 LVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDP 269
LVLTA DGG P RSGT I +I++D NDNAP F V + EN P+GT LL + ATDP
Sbjct: 210 LVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDP 269
Query: 270 DEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPA 329
DEG NG + YSF + + LF L+ SG I +LG +D+E+S FY+I A D P
Sbjct: 270 DEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHD--GPG 326
Query: 330 MEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDI 389
+ + V V D NDNAPEV + SL + V ES+ GTV+ LFNV D DSG NG V+ I
Sbjct: 327 LRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSI 386
Query: 390 SPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVN 448
+LPF + K N+Y LLT + LDRE S Y I + A+D G+P L I L + D+N
Sbjct: 387 PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDIN 446
Query: 449 DNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVY 508
DN P F Y+AYI EN P G+ + ++ A DPD+GDNAR+TYS+ + QGAP SS+V
Sbjct: 447 DNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVS 506
Query: 509 VNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPR 568
+N G ++A +FDYE + LQ+++ DSG PPL +N SL +FVLD+NDN P +L+P
Sbjct: 507 INSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPT 566
Query: 569 -PDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGE 627
P + + PRSA G LVTKV AVD D+G NAWLSYSLL +S+ PGLF V HTGE
Sbjct: 567 FPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLL-KSSEPGLFAVGLHTGE 625
Query: 628 VRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------EMPKSSDFL 681
VRTARALL+ D+ Q++VV+V+D+G P LS+T T+ + + D P+ + S+D
Sbjct: 626 VRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSAD-- 683
Query: 682 IHPPERSDLTLYLIVALATVSLLSLVTFTFLSA 714
P+ S LTLYL+VA+A VS + L T L A
Sbjct: 684 ---PDDSGLTLYLVVAVAAVSCVFLAFVTVLLA 713
>gi|11036656 protocadherin beta 7 precursor [Homo sapiens]
Length = 793
Score = 608 bits (1568), Expect = e-174
Identities = 336/789 (42%), Positives = 495/789 (62%), Gaps = 38/789 (4%)
Query: 12 KWQVLCMLSLCCWGWVSGQ-LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEE 70
K QVL + W + LRY V EE+E GT + N+A+DLGL + +L +R ++ S++
Sbjct: 11 KRQVLFLCVFLGMSWAGAEPLRYFVAEETERGTFLTNLAKDLGLGVGELRARGTRIVSDQ 70
Query: 71 NGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNS 130
N + LS ++G L +N+K+DRE LCG C+LP Q++ E P ++ R E+ + D+ND++
Sbjct: 71 NMQILLLSSLTGDLLLNEKLDREELCGPREPCVLPFQLLLEKPFQIFRAELWVRDINDHA 130
Query: 131 PSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKP 190
P F E ++I ES GA F L+SAQD DVGTN++S YT+SPN++F +NV +G
Sbjct: 131 PVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTISPNAYFHINVHDSGEGNI 190
Query: 191 FPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVG 250
+PELVL Q LDRE L LTA+DGG+P RSGT L+ ++VLD+NDNAP F S+ +V
Sbjct: 191 YPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQ 250
Query: 251 IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDF 310
+PEN+P+G++++ ++A D D G+NG++ Y+F + +E + F ++P+SG++H+ +D+
Sbjct: 251 VPENSPVGSMVVSVSARDLDTGSNGEIAYAF-SYATERILKTFQINPTSGSLHLKAQLDY 309
Query: 311 EESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVG 370
E + Y + +A+D G + G C + VDV D+NDN PE+LL+SL +P+ E++P TVV
Sbjct: 310 EAIQTYTLTIQAKDGG--GLSGKCTVVVDVTDINDNRPELLLSSLTSPIAENSP-ETVVA 366
Query: 371 LFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDA 429
+F +RDRDSG NG+ I D+PF +KPS EN Y+L+T +PLDRE + Y I + +D
Sbjct: 367 VFRIRDRDSGNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDL 426
Query: 430 GSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARL 489
G+P L I + +SDVNDNAP F Q YT ++ EN P + +V+A+D D+G NA++
Sbjct: 427 GTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDSGTNAQV 486
Query: 490 TYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTS 549
YS++ +Q P +S V +N ++G +FA R+ DYE LQ + VG D GSP L +
Sbjct: 487 IYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEAL 546
Query: 550 LHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSL 609
+ V VLD NDN+P VL+P + + LPR+A PG LVTKV AVD D+G NAWLSY L
Sbjct: 547 VRVLVLDANDNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQL 606
Query: 610 LPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDE 669
L ++T PGLF V H GEVRTAR L E D+ Q++VVLV+DNG+P S+TAT+ ++L D
Sbjct: 607 L-KATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATLHVLLVDG 665
Query: 670 DPE---EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSA--KCLQGNADGD 724
+ +P+++ P + + LT+YL+VALA+VS L L++ A C + A
Sbjct: 666 FSQPYLRLPEAA-----PDQANSLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAAPV 720
Query: 725 GGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDG 784
G C + P P + +S GTL SQS+ Y C + S
Sbjct: 721 GR----CSVPEGPFPRHL------VDLSGTGTL-----------SQSYQYEVCLTGGSGT 759
Query: 785 SDFTFLRPL 793
++F FL+P+
Sbjct: 760 NEFKFLKPI 768
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 604 bits (1557), Expect = e-172
Identities = 334/707 (47%), Positives = 454/707 (64%), Gaps = 15/707 (2%)
Query: 15 VLCML--SLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENG 72
+LC L +LC G SGQ+RYSV EE + G+ VGN+A DLGL+ +L R +++ S
Sbjct: 15 LLCALLGTLCETG--SGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRT 72
Query: 73 RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
+ FSL+ SG+L ++IDRE LC CL+ + ++ E L++ VE+EI D+NDN+P+
Sbjct: 73 QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPN 132
Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
F T E E++I E G RFP+ +A DPDVG N++ Y LSPN +FSL V ++ +G +P
Sbjct: 133 FPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYP 192
Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
ELVLE+ LDRE + HQLVL A DGG P SG I VIVLD NDN P F RV +
Sbjct: 193 ELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVW 252
Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
EN P+GT LL +NATDPDEG N Q+ Y D + +F L+ SG + +L +D+E+
Sbjct: 253 ENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLDYED 311
Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
+ FYEI A+D P + I V V DVNDNAPE+ + SL + V E VG + L
Sbjct: 312 AMFYEIKIEAQD--GPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALI 369
Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGS 431
+V DRDSG+NG+V + + +LPF+++ S + +Y L+T+ LDRE S Y I L ASD GS
Sbjct: 370 DVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGS 429
Query: 432 PSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTY 491
P L I L++ D+NDN P F Y+AYI EN P G+ + +V A DPD+ +NAR+TY
Sbjct: 430 PPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITY 489
Query: 492 SIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLH 551
++ + +QGAP SSFV +N G ++A R+FDYE + L+++V DSG+PPL +N SL+
Sbjct: 490 ALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLN 549
Query: 552 VFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLL 610
+FVLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D+G NAWLSY LL
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 611 PQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDED 670
+++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T T+ + + D
Sbjct: 610 -KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRI 668
Query: 671 PEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSA 714
P+ + + P P SDLTLYL+VA+A VS + L L A
Sbjct: 669 PDILADLGS--LEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLA 713
>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
[Homo sapiens]
Length = 829
Score = 604 bits (1557), Expect = e-172
Identities = 334/707 (47%), Positives = 454/707 (64%), Gaps = 15/707 (2%)
Query: 15 VLCML--SLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENG 72
+LC L +LC G SGQ+RYSV EE + G+ VGN+A DLGL+ +L R +++ S
Sbjct: 15 LLCALLGTLCETG--SGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRT 72
Query: 73 RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
+ FSL+ SG+L ++IDRE LC CL+ + ++ E L++ VE+EI D+NDN+P+
Sbjct: 73 QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPN 132
Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
F T E E++I E G RFP+ +A DPDVG N++ Y LSPN +FSL V ++ +G +P
Sbjct: 133 FPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYP 192
Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
ELVLE+ LDRE + HQLVL A DGG P SG I VIVLD NDN P F RV +
Sbjct: 193 ELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVW 252
Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
EN P+GT LL +NATDPDEG N Q+ Y D + +F L+ SG + +L +D+E+
Sbjct: 253 ENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLDYED 311
Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
+ FYEI A+D P + I V V DVNDNAPE+ + SL + V E VG + L
Sbjct: 312 AMFYEIKIEAQD--GPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALI 369
Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGS 431
+V DRDSG+NG+V + + +LPF+++ S + +Y L+T+ LDRE S Y I L ASD GS
Sbjct: 370 DVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGS 429
Query: 432 PSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTY 491
P L I L++ D+NDN P F Y+AYI EN P G+ + +V A DPD+ +NAR+TY
Sbjct: 430 PPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITY 489
Query: 492 SIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLH 551
++ + +QGAP SSFV +N G ++A R+FDYE + L+++V DSG+PPL +N SL+
Sbjct: 490 ALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLN 549
Query: 552 VFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLL 610
+FVLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D+G NAWLSY LL
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 611 PQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDED 670
+++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T T+ + + D
Sbjct: 610 -KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRI 668
Query: 671 PEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSA 714
P+ + + P P SDLTLYL+VA+A VS + L L A
Sbjct: 669 PDILADLGS--LEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLA 713
>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 600 bits (1546), Expect = e-171
Identities = 338/738 (45%), Positives = 461/738 (62%), Gaps = 16/738 (2%)
Query: 1 MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
M T QL G+ +LC L W + Q+RYSV EE+E G +VGN+++DL L+ +L
Sbjct: 1 MAAPTKCQLRGRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELA 60
Query: 61 SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
RR+++ S + FSL+ SG L +IDRE LC S CL+ +V+ E ++L +E
Sbjct: 61 ERRVRIVSRGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIE 120
Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
+E+ D+ND++P F E++I+E A GAR+PL A DPDVG N++ Y LSPN HFSL
Sbjct: 121 IEVTDINDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSL 180
Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
NV+T +G PELVLE+ LDRE H LVLTA DGG P RS T I V VLD NDNAP
Sbjct: 181 NVQTGDNGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAP 240
Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
F + RV + EN P GT LL A+D DEG NG++ Y F +E LF L+ ++G
Sbjct: 241 VFAQRIYRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFW-KINEKQSLLFQLNENTG 299
Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
I +D+EE FYE+ +A D G ++G + + V DVNDN PEV + SL +PV
Sbjct: 300 EISTAKSLDYEECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVR 357
Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSH 419
E P GTV+ LFN DRDSG+NG+V I +L F ++ S E++Y LLT+Q LDRE S
Sbjct: 358 EDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASE 417
Query: 420 YIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAAS 479
Y I + A+D G+P L + I L ++D+NDN P F+Q Y+ Y+ EN G+ + +V A
Sbjct: 418 YNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAY 477
Query: 480 DPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDS 539
DPD+ +N+R+ YS+ + +QG+P S++V +N + G ++A +FDYE + LQ+ V DS
Sbjct: 478 DPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDS 537
Query: 540 GSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDAD 598
GSPPL +N SL +FVLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D
Sbjct: 538 GSPPLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRD 597
Query: 599 AGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSS 658
+G NAWLSY L +++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+
Sbjct: 598 SGQNAWLSYRLF-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656
Query: 659 TATVLLVLEDEDPEEMPKSSDFLIHPP-ERSDLTLYLIVALATVS---------LLSLVT 708
T T+ + + D P+ + I E SDLTLYL+VA+A VS LL+L
Sbjct: 657 TVTLTVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRL 716
Query: 709 FTFLSAKCLQGNADGDGG 726
+ S+ L+ +DG G
Sbjct: 717 RHWHSSHLLRATSDGLAG 734
>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
[Homo sapiens]
Length = 828
Score = 600 bits (1546), Expect = e-171
Identities = 338/738 (45%), Positives = 461/738 (62%), Gaps = 16/738 (2%)
Query: 1 MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
M T QL G+ +LC L W + Q+RYSV EE+E G +VGN+++DL L+ +L
Sbjct: 1 MAAPTKCQLRGRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELA 60
Query: 61 SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
RR+++ S + FSL+ SG L +IDRE LC S CL+ +V+ E ++L +E
Sbjct: 61 ERRVRIVSRGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIE 120
Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
+E+ D+ND++P F E++I+E A GAR+PL A DPDVG N++ Y LSPN HFSL
Sbjct: 121 IEVTDINDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSL 180
Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
NV+T +G PELVLE+ LDRE H LVLTA DGG P RS T I V VLD NDNAP
Sbjct: 181 NVQTGDNGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAP 240
Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
F + RV + EN P GT LL A+D DEG NG++ Y F +E LF L+ ++G
Sbjct: 241 VFAQRIYRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFW-KINEKQSLLFQLNENTG 299
Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
I +D+EE FYE+ +A D G ++G + + V DVNDN PEV + SL +PV
Sbjct: 300 EISTAKSLDYEECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVR 357
Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSH 419
E P GTV+ LFN DRDSG+NG+V I +L F ++ S E++Y LLT+Q LDRE S
Sbjct: 358 EDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASE 417
Query: 420 YIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAAS 479
Y I + A+D G+P L + I L ++D+NDN P F+Q Y+ Y+ EN G+ + +V A
Sbjct: 418 YNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAY 477
Query: 480 DPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDS 539
DPD+ +N+R+ YS+ + +QG+P S++V +N + G ++A +FDYE + LQ+ V DS
Sbjct: 478 DPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDS 537
Query: 540 GSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDAD 598
GSPPL +N SL +FVLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D
Sbjct: 538 GSPPLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRD 597
Query: 599 AGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSS 658
+G NAWLSY L +++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+
Sbjct: 598 SGQNAWLSYRLF-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656
Query: 659 TATVLLVLEDEDPEEMPKSSDFLIHPP-ERSDLTLYLIVALATVS---------LLSLVT 708
T T+ + + D P+ + I E SDLTLYL+VA+A VS LL+L
Sbjct: 657 TVTLTVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRL 716
Query: 709 FTFLSAKCLQGNADGDGG 726
+ S+ L+ +DG G
Sbjct: 717 RHWHSSHLLRATSDGLAG 734
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 599 bits (1544), Expect = e-171
Identities = 320/722 (44%), Positives = 466/722 (64%), Gaps = 7/722 (0%)
Query: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
+L +L L SGQL YSV EE++ GT VG +AQDLGL++ +L+ R ++ S+ +G
Sbjct: 15 LLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74
Query: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
++L +G L VN +IDRE LCG S C + ++V+ + PL++ VEVE+ D+NDN+P F
Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFP 134
Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
+ + ISES G+RF L+ A D D+GTN++ Y+L +F+L+VK + L
Sbjct: 135 MAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGL 194
Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
VL++ L+RE +H L++TA+DGG P +GTT + + VLD+NDNAP F+ ++ +V + EN
Sbjct: 195 VLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLEN 254
Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
AP GTL++ +NATD DEG N + YSF S + + F LDP +G I V G IDFEES+
Sbjct: 255 APNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESK 314
Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
YEI A D+G P M HC + +++ D+NDN PE+++ SL+ PVLE +P+ TV+ L +V
Sbjct: 315 SYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISV 374
Query: 375 RDRDSGRNGEVSLDISPDLPFQ-IKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
DRDSG NG+V+ ++P +PF+ + +N+YSL+ PLDRE+ S Y + + A D GSPS
Sbjct: 375 SDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPS 434
Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
L ++ + ++DVNDNAP F+Q YT ++ EN PPG + TV+A D D +NA ++YS+
Sbjct: 435 LWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
V +V SS+V V+ E G+++A + D+E L++LQ V RD+G PPL +N +L VF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
VLDENDNAPA+L PR A L PRS G +V KV AVDAD+G+NAWLSY L P
Sbjct: 555 VLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPG 614
Query: 613 STAPGL-FLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVL--LVLEDE 669
+ + F V +TGE+ T RAL E D+ +++VLV+D+G+PSL++TATVL LV +
Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674
Query: 670 DPEEMPKSSDFLIHPPER-SDLTLYLIVALATV-SLLSLVTFTFLSAKCLQGNADGDGGG 727
P+ ++S P D+ +YLIVA+ V SLL L + + +C +GD G
Sbjct: 675 APKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGP 734
Query: 728 GQ 729
G+
Sbjct: 735 GK 736
>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 599 bits (1544), Expect = e-171
Identities = 320/722 (44%), Positives = 466/722 (64%), Gaps = 7/722 (0%)
Query: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
+L +L L SGQL YSV EE++ GT VG +AQDLGL++ +L+ R ++ S+ +G
Sbjct: 15 LLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74
Query: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
++L +G L VN +IDRE LCG S C + ++V+ + PL++ VEVE+ D+NDN+P F
Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFP 134
Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
+ + ISES G+RF L+ A D D+GTN++ Y+L +F+L+VK + L
Sbjct: 135 MAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGL 194
Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
VL++ L+RE +H L++TA+DGG P +GTT + + VLD+NDNAP F+ ++ +V + EN
Sbjct: 195 VLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLEN 254
Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
AP GTL++ +NATD DEG N + YSF S + + F LDP +G I V G IDFEES+
Sbjct: 255 APNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESK 314
Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
YEI A D+G P M HC + +++ D+NDN PE+++ SL+ PVLE +P+ TV+ L +V
Sbjct: 315 SYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISV 374
Query: 375 RDRDSGRNGEVSLDISPDLPFQ-IKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
DRDSG NG+V+ ++P +PF+ + +N+YSL+ PLDRE+ S Y + + A D GSPS
Sbjct: 375 SDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPS 434
Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
L ++ + ++DVNDNAP F+Q YT ++ EN PPG + TV+A D D +NA ++YS+
Sbjct: 435 LWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
V +V SS+V V+ E G+++A + D+E L++LQ V RD+G PPL +N +L VF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
VLDENDNAPA+L PR A L PRS G +V KV AVDAD+G+NAWLSY L P
Sbjct: 555 VLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPG 614
Query: 613 STAPGL-FLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVL--LVLEDE 669
+ + F V +TGE+ T RAL E D+ +++VLV+D+G+PSL++TATVL LV +
Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674
Query: 670 DPEEMPKSSDFLIHPPER-SDLTLYLIVALATV-SLLSLVTFTFLSAKCLQGNADGDGGG 727
P+ ++S P D+ +YLIVA+ V SLL L + + +C +GD G
Sbjct: 675 APKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGP 734
Query: 728 GQ 729
G+
Sbjct: 735 GK 736
>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
[Homo sapiens]
Length = 810
Score = 599 bits (1544), Expect = e-171
Identities = 332/748 (44%), Positives = 472/748 (63%), Gaps = 26/748 (3%)
Query: 18 MLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSL 77
+LSL C G +S Q+RY++ EE G+ VG +A+DLGL + +L +R+L++ +E+ YF++
Sbjct: 19 LLSLFC-GAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAED---YFNV 74
Query: 78 SLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPE 137
SL SG L VN +IDRE +CG C L + V E+P+ + V V I D+NDN+P F
Sbjct: 75 SLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKG 134
Query: 138 REMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLE 197
++ I ESA G +F LDSAQD DV N++ YT++PN +FSL+ K DG +P L+LE
Sbjct: 135 IDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLE 194
Query: 198 QQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPI 257
+ LDRE Q+ H+L+LTA+DGG P SGTT I + V D NDNAP F V RV + EN P
Sbjct: 195 KPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPW 254
Query: 258 GTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYE 317
GT +LR+ ATD DEG N ++ Y+F S +LF L+P++G I G +DFEE+ Y
Sbjct: 255 GTSVLRVMATDQDEGINAEITYAF--LNSPISTSLFNLNPNTGDITTNGTLDFEETSRYV 312
Query: 318 IHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDR 377
+ A+D G HC +Q+++ D NDNAPEV S +N + E + +GTV+ L VRD+
Sbjct: 313 LSVEAKDGG--VHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDK 370
Query: 378 DSGRNGEVSLDISPDLPFQIK-PSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
DSG+NG V+ ++PF+++ S+N+Y L+ + L+RE T+ Y + ++A+D G P+L
Sbjct: 371 DSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSS 430
Query: 437 HLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGN 496
+I L+ISD+NDNAP F+Q Y ++ EN PPG+ + V+ASDPD G N R++YSI+ +
Sbjct: 431 RTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILAS 490
Query: 497 QVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLD 556
++ S+V V+P+ G +FAQR FD+E L+ ++ + RD GSP L AN SL V V D
Sbjct: 491 DLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGD 550
Query: 557 ENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTA 615
NDNAP VL+P + SA +PR+A PG LVTKV AVDAD+GHNAWLSY +L Q++
Sbjct: 551 LNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVL-QASE 609
Query: 616 PGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMP 675
PGLF + TGEVRTARAL + D+ Q+++V VRD G P LS+TAT+ L+ D E +P
Sbjct: 610 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 669
Query: 676 KSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG----GQCC 731
SD +++L YL+VALA +S+L L+ A L+ ++ D G G C
Sbjct: 670 DLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLCS 729
Query: 732 RRQDSPSPDFYKQSSPNLQVSSDGTLKY 759
+ P+ S+GTL Y
Sbjct: 730 KSGPGVPPN-----------HSEGTLPY 746
>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
[Homo sapiens]
Length = 927
Score = 599 bits (1544), Expect = e-171
Identities = 332/748 (44%), Positives = 472/748 (63%), Gaps = 26/748 (3%)
Query: 18 MLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSL 77
+LSL C G +S Q+RY++ EE G+ VG +A+DLGL + +L +R+L++ +E+ YF++
Sbjct: 19 LLSLFC-GAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAED---YFNV 74
Query: 78 SLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPE 137
SL SG L VN +IDRE +CG C L + V E+P+ + V V I D+NDN+P F
Sbjct: 75 SLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKG 134
Query: 138 REMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLE 197
++ I ESA G +F LDSAQD DV N++ YT++PN +FSL+ K DG +P L+LE
Sbjct: 135 IDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLE 194
Query: 198 QQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPI 257
+ LDRE Q+ H+L+LTA+DGG P SGTT I + V D NDNAP F V RV + EN P
Sbjct: 195 KPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPW 254
Query: 258 GTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYE 317
GT +LR+ ATD DEG N ++ Y+F S +LF L+P++G I G +DFEE+ Y
Sbjct: 255 GTSVLRVMATDQDEGINAEITYAF--LNSPISTSLFNLNPNTGDITTNGTLDFEETSRYV 312
Query: 318 IHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDR 377
+ A+D G HC +Q+++ D NDNAPEV S +N + E + +GTV+ L VRD+
Sbjct: 313 LSVEAKDGG--VHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDK 370
Query: 378 DSGRNGEVSLDISPDLPFQIK-PSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
DSG+NG V+ ++PF+++ S+N+Y L+ + L+RE T+ Y + ++A+D G P+L
Sbjct: 371 DSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSS 430
Query: 437 HLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGN 496
+I L+ISD+NDNAP F+Q Y ++ EN PPG+ + V+ASDPD G N R++YSI+ +
Sbjct: 431 RTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILAS 490
Query: 497 QVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLD 556
++ S+V V+P+ G +FAQR FD+E L+ ++ + RD GSP L AN SL V V D
Sbjct: 491 DLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGD 550
Query: 557 ENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTA 615
NDNAP VL+P + SA +PR+A PG LVTKV AVDAD+GHNAWLSY +L Q++
Sbjct: 551 LNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVL-QASE 609
Query: 616 PGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMP 675
PGLF + TGEVRTARAL + D+ Q+++V VRD G P LS+TAT+ L+ D E +P
Sbjct: 610 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 669
Query: 676 KSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG----GQCC 731
SD +++L YL+VALA +S+L L+ A L+ ++ D G G C
Sbjct: 670 DLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLCS 729
Query: 732 RRQDSPSPDFYKQSSPNLQVSSDGTLKY 759
+ P+ S+GTL Y
Sbjct: 730 KSGPGVPPN-----------HSEGTLPY 746
>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 598 bits (1541), Expect = e-171
Identities = 330/712 (46%), Positives = 451/712 (63%), Gaps = 11/712 (1%)
Query: 12 KWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEEN 71
K +LC L W +GQ+RYSV EE + G+ VGN+A+DLGL+ L + +++ S
Sbjct: 12 KLVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGR 71
Query: 72 GRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSP 131
+ F+L+ SG+L +IDRE LC S CLL ++ E L + VEVEI D+NDN+P
Sbjct: 72 SQLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAP 131
Query: 132 SFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPF 191
F E E++ISE+ G R PL +A D DVG N + Y L+PN HFSL+V+ DG +
Sbjct: 132 RFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKY 191
Query: 192 PELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGI 251
PELVLE+ LDRE +A H LVL A DGG P SGT+ I V VLD NDNAP F R+ I
Sbjct: 192 PELVLERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISI 251
Query: 252 PENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFE 311
PEN +GT +L + ATD DEG Q+ Y F + + +F L +SG + ++ +D+E
Sbjct: 252 PENTLVGTRILTVTATDADEGYYAQVVY-FLEKSPGETSEVFELKSTSGELTIIKDLDYE 310
Query: 312 ESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGL 371
++ F+EI A+D P + + V V DVNDNAPE + S + V E + GT++GL
Sbjct: 311 DATFHEIDIEAQD--GPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGL 368
Query: 372 FNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAG 430
FNV DRDSG+N + + DLPF+++ S +N+Y L+T++ LDRE S Y I L A D G
Sbjct: 369 FNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGG 428
Query: 431 SPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLT 490
+PSL I L ++D+NDNAP F++ Y+ YI EN P G+ + +V A DPD+ DNA +T
Sbjct: 429 NPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488
Query: 491 YSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSL 550
YS + VQGAP SS++ +N + G ++A R+FDYE L+ LQ+ V RDSG+PPL +N SL
Sbjct: 489 YSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSL 548
Query: 551 HVFVLDENDNAPAVLHPR-PDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSL 609
+FVLD+NDNAP +L+P P + + PRSA PG LVTKV AVD D+G NAWLSY L
Sbjct: 549 SLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHL 608
Query: 610 LPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDE 669
L +++ PGLF V HTGEVRTARALL+ D+ Q +VV ++D+G P LS+T T+ + + D
Sbjct: 609 L-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLTVAVADR 667
Query: 670 DPEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQ 718
P+ + + P P SDLTLYL+VA+A VS + L L A L+
Sbjct: 668 IPDILADLGS--LEPSAIPNDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLR 717
>gi|14196462 protocadherin gamma subfamily A, 2 isoform 2 precursor
[Homo sapiens]
Length = 823
Score = 598 bits (1541), Expect = e-171
Identities = 330/712 (46%), Positives = 451/712 (63%), Gaps = 11/712 (1%)
Query: 12 KWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEEN 71
K +LC L W +GQ+RYSV EE + G+ VGN+A+DLGL+ L + +++ S
Sbjct: 12 KLVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGR 71
Query: 72 GRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSP 131
+ F+L+ SG+L +IDRE LC S CLL ++ E L + VEVEI D+NDN+P
Sbjct: 72 SQLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAP 131
Query: 132 SFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPF 191
F E E++ISE+ G R PL +A D DVG N + Y L+PN HFSL+V+ DG +
Sbjct: 132 RFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKY 191
Query: 192 PELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGI 251
PELVLE+ LDRE +A H LVL A DGG P SGT+ I V VLD NDNAP F R+ I
Sbjct: 192 PELVLERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISI 251
Query: 252 PENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFE 311
PEN +GT +L + ATD DEG Q+ Y F + + +F L +SG + ++ +D+E
Sbjct: 252 PENTLVGTRILTVTATDADEGYYAQVVY-FLEKSPGETSEVFELKSTSGELTIIKDLDYE 310
Query: 312 ESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGL 371
++ F+EI A+D P + + V V DVNDNAPE + S + V E + GT++GL
Sbjct: 311 DATFHEIDIEAQD--GPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGL 368
Query: 372 FNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAG 430
FNV DRDSG+N + + DLPF+++ S +N+Y L+T++ LDRE S Y I L A D G
Sbjct: 369 FNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGG 428
Query: 431 SPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLT 490
+PSL I L ++D+NDNAP F++ Y+ YI EN P G+ + +V A DPD+ DNA +T
Sbjct: 429 NPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488
Query: 491 YSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSL 550
YS + VQGAP SS++ +N + G ++A R+FDYE L+ LQ+ V RDSG+PPL +N SL
Sbjct: 489 YSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSL 548
Query: 551 HVFVLDENDNAPAVLHPR-PDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSL 609
+FVLD+NDNAP +L+P P + + PRSA PG LVTKV AVD D+G NAWLSY L
Sbjct: 549 SLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHL 608
Query: 610 LPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDE 669
L +++ PGLF V HTGEVRTARALL+ D+ Q +VV ++D+G P LS+T T+ + + D
Sbjct: 609 L-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLTVAVADR 667
Query: 670 DPEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQ 718
P+ + + P P SDLTLYL+VA+A VS + L L A L+
Sbjct: 668 IPDILADLGS--LEPSAIPNDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLR 717
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 595 bits (1534), Expect = e-170
Identities = 332/701 (47%), Positives = 449/701 (64%), Gaps = 23/701 (3%)
Query: 26 WVSG--QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGA 83
W +G Q+RYSV EE E G+ VG++++DLGL+ +L R +++ + F+L+ SG+
Sbjct: 24 WETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGS 83
Query: 84 LAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRIS 143
L +IDRE LC + C L + ++ E +++ VEVE+ D+NDN+P F E E++IS
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 144 ESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDRE 203
E+AA+ RFPL A DPD+G N++ Y LSPN+HFSL V+ DG +PELVL++ LDRE
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDRE 203
Query: 204 AQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR 263
+A H LVLTA DGG P R+GT I V+VLD NDNAP F R +PEN +GT LL
Sbjct: 204 EKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV 263
Query: 264 LNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
+NATDPDEG N ++ YSF + + +F LD +SG I +G +D EES FY++ +A
Sbjct: 264 VNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAM 322
Query: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNG 383
D + + V DVNDNAPEV+L SLA+ V E++P GT++ L NV D+DS NG
Sbjct: 323 DNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENG 380
Query: 384 EVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRL 442
+V I +LPF+++ S N+YSL+T LDRE Y I + A+D G+P L I L
Sbjct: 381 QVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISL 440
Query: 443 NISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAP 502
N++D NDN P F Q Y+AYI EN P G L +V A DPD +NA++TYS+ N +QGA
Sbjct: 441 NVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGAS 500
Query: 503 ASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAP 562
SS+V +N + G ++A +FDYE + LQ+ V RD+G PPL +N SL +FVLD+NDNAP
Sbjct: 501 LSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAP 560
Query: 563 AVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLV 621
+L+P + S L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V
Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL-KASEPGLFSV 619
Query: 622 STHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE--------E 673
HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T T+ + + D P+ E
Sbjct: 620 GLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLE 679
Query: 674 MPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSA 714
P +S E SDLTLYL+VA+A VS + L L A
Sbjct: 680 SPANS-------ETSDLTLYLVVAVAAVSCVFLAFVILLLA 713
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 595 bits (1534), Expect = e-170
Identities = 332/701 (47%), Positives = 449/701 (64%), Gaps = 23/701 (3%)
Query: 26 WVSG--QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGA 83
W +G Q+RYSV EE E G+ VG++++DLGL+ +L R +++ + F+L+ SG+
Sbjct: 24 WETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGS 83
Query: 84 LAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRIS 143
L +IDRE LC + C L + ++ E +++ VEVE+ D+NDN+P F E E++IS
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 144 ESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDRE 203
E+AA+ RFPL A DPD+G N++ Y LSPN+HFSL V+ DG +PELVL++ LDRE
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDRE 203
Query: 204 AQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR 263
+A H LVLTA DGG P R+GT I V+VLD NDNAP F R +PEN +GT LL
Sbjct: 204 EKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV 263
Query: 264 LNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
+NATDPDEG N ++ YSF + + +F LD +SG I +G +D EES FY++ +A
Sbjct: 264 VNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAM 322
Query: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNG 383
D + + V DVNDNAPEV+L SLA+ V E++P GT++ L NV D+DS NG
Sbjct: 323 DNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENG 380
Query: 384 EVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRL 442
+V I +LPF+++ S N+YSL+T LDRE Y I + A+D G+P L I L
Sbjct: 381 QVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISL 440
Query: 443 NISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAP 502
N++D NDN P F Q Y+AYI EN P G L +V A DPD +NA++TYS+ N +QGA
Sbjct: 441 NVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGAS 500
Query: 503 ASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAP 562
SS+V +N + G ++A +FDYE + LQ+ V RD+G PPL +N SL +FVLD+NDNAP
Sbjct: 501 LSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAP 560
Query: 563 AVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLV 621
+L+P + S L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V
Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL-KASEPGLFSV 619
Query: 622 STHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE--------E 673
HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T T+ + + D P+ E
Sbjct: 620 GLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLE 679
Query: 674 MPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSA 714
P +S E SDLTLYL+VA+A VS + L L A
Sbjct: 680 SPANS-------ETSDLTLYLVVAVAAVSCVFLAFVILLLA 713
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 595 bits (1533), Expect = e-170
Identities = 331/721 (45%), Positives = 455/721 (63%), Gaps = 12/721 (1%)
Query: 3 PKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSR 62
P+ PQ + + +L +L WG + Q+RYS+ EE E G+ VGN+ +DLGL+ +L
Sbjct: 4 PQRHPQRSEQVLLLTLLGTL-WGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEH 62
Query: 63 RLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
+++ S + FSL+ +G+L +IDRE LC S CL+ ++ E L L VEVE
Sbjct: 63 GVRIVSRGRMQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVE 122
Query: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNV 182
I+D+NDN+P F E E++I E+AA +RFPL DPDVG N++ + LS NSHFS++V
Sbjct: 123 IVDINDNTPRFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDV 182
Query: 183 KTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTF 242
++ G +PELVLE LDRE +A ++LVLTA+DGG P RS I V VLD+NDN P F
Sbjct: 183 QSEAHGPKYPELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMF 242
Query: 243 QSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAI 302
V RV +PEN P+GT +L + ATD DEG +G++ YSF T E + +F L+ +G I
Sbjct: 243 TQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEI 301
Query: 303 HVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLES 362
+D+E+S FYE+ ARD P + + + + DVNDN PEV++ S + + ES
Sbjct: 302 STSANLDYEDSSFYELGVEARD--GPGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAES 359
Query: 363 TPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYI 421
P GTV+ LF V DRDSG NG V+ I LPF+++ S N+Y L+T+ LDRE Y
Sbjct: 360 APPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYN 419
Query: 422 IELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDP 481
I + A+D G+P L I LN++D NDN P F Y+ Y+LEN P G+ + +V A DP
Sbjct: 420 ITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDP 479
Query: 482 DTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGS 541
D NA+++YS+ + +QGAP SS+V +N + G ++A R+FDYE L+ LQ+ V DSG
Sbjct: 480 DVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGD 539
Query: 542 PPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAG 600
PPL +N SL +FVLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D+G
Sbjct: 540 PPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSG 599
Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
NAWLSY LL +++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T
Sbjct: 600 QNAWLSYRLL-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 658
Query: 661 TVLLVLEDEDPEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCL 717
T+ + + D P+ + + P P SDLTLYL+VA+A VS + L L A L
Sbjct: 659 TLTVAVADRIPDILADLGS--LEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRL 716
Query: 718 Q 718
Q
Sbjct: 717 Q 717
>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 595 bits (1533), Expect = e-170
Identities = 331/721 (45%), Positives = 455/721 (63%), Gaps = 12/721 (1%)
Query: 3 PKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSR 62
P+ PQ + + +L +L WG + Q+RYS+ EE E G+ VGN+ +DLGL+ +L
Sbjct: 4 PQRHPQRSEQVLLLTLLGTL-WGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEH 62
Query: 63 RLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
+++ S + FSL+ +G+L +IDRE LC S CL+ ++ E L L VEVE
Sbjct: 63 GVRIVSRGRMQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVE 122
Query: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNV 182
I+D+NDN+P F E E++I E+AA +RFPL DPDVG N++ + LS NSHFS++V
Sbjct: 123 IVDINDNTPRFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDV 182
Query: 183 KTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTF 242
++ G +PELVLE LDRE +A ++LVLTA+DGG P RS I V VLD+NDN P F
Sbjct: 183 QSEAHGPKYPELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMF 242
Query: 243 QSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAI 302
V RV +PEN P+GT +L + ATD DEG +G++ YSF T E + +F L+ +G I
Sbjct: 243 TQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEI 301
Query: 303 HVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLES 362
+D+E+S FYE+ ARD P + + + + DVNDN PEV++ S + + ES
Sbjct: 302 STSANLDYEDSSFYELGVEARD--GPGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAES 359
Query: 363 TPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYI 421
P GTV+ LF V DRDSG NG V+ I LPF+++ S N+Y L+T+ LDRE Y
Sbjct: 360 APPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYN 419
Query: 422 IELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDP 481
I + A+D G+P L I LN++D NDN P F Y+ Y+LEN P G+ + +V A DP
Sbjct: 420 ITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDP 479
Query: 482 DTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGS 541
D NA+++YS+ + +QGAP SS+V +N + G ++A R+FDYE L+ LQ+ V DSG
Sbjct: 480 DVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGD 539
Query: 542 PPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAG 600
PPL +N SL +FVLD+NDNAP +L+P + S L PRSA PG LVTKV AVD D+G
Sbjct: 540 PPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSG 599
Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
NAWLSY LL +++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T
Sbjct: 600 QNAWLSYRLL-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 658
Query: 661 TVLLVLEDEDPEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCL 717
T+ + + D P+ + + P P SDLTLYL+VA+A VS + L L A L
Sbjct: 659 TLTVAVADRIPDILADLGS--LEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRL 716
Query: 718 Q 718
Q
Sbjct: 717 Q 717
>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 594 bits (1531), Expect = e-169
Identities = 327/707 (46%), Positives = 458/707 (64%), Gaps = 8/707 (1%)
Query: 3 PKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSR 62
P++ P+ G+ +LC L W GQ+RYSV EE++ G+ VGN+++DLGL L
Sbjct: 4 PQSRPR-RGELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKH 62
Query: 63 RLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
+++ S + F+L+ SG+L +IDRE LC S CL+ + + E +L VE+E
Sbjct: 63 GVRIVSRGRTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIE 122
Query: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNV 182
I+D+NDN+P F + E++I+E A GAR+PL A DPDVG N++ Y LSPN HFSL+V
Sbjct: 123 IIDINDNNPKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDV 182
Query: 183 KTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTF 242
+T +G PELVLE+ LDRE +A H LVLTA DGG P RS T I V VLD NDNAP F
Sbjct: 183 QTGDNGAINPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVF 242
Query: 243 QSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAI 302
+ RV + EN P GT LL + A+DPDEG NG++ Y F +E LF L+ ++G I
Sbjct: 243 PHPIYRVKVLENMPPGTRLLTVTASDPDEGINGKVAYKF-RKINEKQTPLFQLNENTGEI 301
Query: 303 HVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLES 362
+ +D+EE FYE+ +A D G A+ G + + V DVNDN PEV++ SL +PVLE+
Sbjct: 302 SIAKSLDYEECSFYEMEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLEN 359
Query: 363 TPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYI 421
+ GTV+ +V D+DSG+NG+V +LPF+++ S N+Y L+T + LDRE S Y
Sbjct: 360 SLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYN 419
Query: 422 IELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDP 481
I ++ASD G+P L I L+++D+NDN P F Y+AYILEN G+ + ++ A DP
Sbjct: 420 ITVMASDLGTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDP 479
Query: 482 DTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGS 541
D+ +NA++TYS+ + +QGAP SS++ +N + G ++A ++FDYE ++ LQ++V DSG
Sbjct: 480 DSQENAQVTYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGD 539
Query: 542 PPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAG 600
PPL +N SL +FVLD+NDNAP +L+P + S L PRSA G LVTKV AVD D+G
Sbjct: 540 PPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSG 599
Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
NAWLSY LL +++ PGLF V HTGEVRTARALL+ D+ Q +VV V+D+G P LS+T
Sbjct: 600 QNAWLSYRLL-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 658
Query: 661 TVLLVLEDEDPEEMPKSSDFLIH-PPERSDLTLYLIVALATVSLLSL 706
T+ + + D PE + + P S LTLYL+VA+A +S + L
Sbjct: 659 TLTVAVADSIPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFL 705
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,803,167
Number of Sequences: 37866
Number of extensions: 1826549
Number of successful extensions: 12060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 4675
Number of HSP's gapped (non-prelim): 700
length of query: 878
length of database: 18,247,518
effective HSP length: 111
effective length of query: 767
effective length of database: 14,044,392
effective search space: 10772048664
effective search space used: 10772048664
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.