Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 14277677

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14277677 protocadherin gamma subfamily C, 3 isoform 2
precursor [Homo sapiens]
         (863 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...  1701   0.0  
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs...  1594   0.0  
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs...   629   e-180
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs...   629   e-180
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs...   624   e-178
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs...   623   e-178
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...   619   e-177
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs...   619   e-177
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs...   619   e-177
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   618   e-177
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur...   618   e-177
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs...   618   e-177
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs...   618   e-177
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur...   616   e-176
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]   614   e-176
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...   614   e-176
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...   610   e-174
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]   610   e-174
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   610   e-174
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...   607   e-173
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]   607   e-173
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur...   605   e-173
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...   603   e-172
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]   603   e-172
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs...   603   e-172
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso...   602   e-172
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   602   e-172
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs...   602   e-172
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]   601   e-172
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...   601   e-172

>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score = 1701 bits (4404), Expect = 0.0
 Identities = 863/863 (100%), Positives = 863/863 (100%)

Query: 1   MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
           MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
Sbjct: 1   MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60

Query: 61  LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
           LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
Sbjct: 61  LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120

Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
           VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
Sbjct: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180

Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
           ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
Sbjct: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240

Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
           APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
Sbjct: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300

Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
           TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
Sbjct: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360

Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
           VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
Sbjct: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420

Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
           PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
Sbjct: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480

Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
           VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
Sbjct: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540

Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
           DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
Sbjct: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600

Query: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
           GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
Sbjct: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660

Query: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
           TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
Sbjct: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720

Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
           KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780

Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFYSYIILRKEWSCFFSD 840
           PLASRQNTLRSCDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFYSYIILRKEWSCFFSD
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFYSYIILRKEWSCFFSD 840

Query: 841 EDVFLVMHSHFQLALPRSKLVPL 863
           EDVFLVMHSHFQLALPRSKLVPL
Sbjct: 841 EDVFLVMHSHFQLALPRSKLVPL 863


>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 934

 Score = 1594 bits (4128), Expect = 0.0
 Identities = 810/810 (100%), Positives = 810/810 (100%)

Query: 1   MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
           MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
Sbjct: 1   MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60

Query: 61  LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
           LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
Sbjct: 61  LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120

Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
           VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
Sbjct: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180

Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
           ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
Sbjct: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240

Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
           APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
Sbjct: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300

Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
           TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
Sbjct: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360

Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
           VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
Sbjct: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420

Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
           PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
Sbjct: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480

Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
           VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
Sbjct: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540

Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
           DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
Sbjct: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600

Query: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
           GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
Sbjct: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660

Query: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
           TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
Sbjct: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720

Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
           KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780

Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQ 810
           PLASRQNTLRSCDPVFYRQVLGAESAPPGQ
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQ 810


>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  629 bits (1622), Expect = e-180
 Identities = 360/816 (44%), Positives = 504/816 (61%), Gaps = 21/816 (2%)

Query: 15  RVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
           R++ + LLLG L +  +  I Y + EE+E+G  VGN+  +LGL    L+ R  R+VS   
Sbjct: 12  RLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGR 71

Query: 74  RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
            + F +N  +G +    R+DREELC   P+C   LE+++E+ +++  VEV I D+NDN P
Sbjct: 72  TQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPP 131

Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
           +F T++ +++++E   PG RFPL  A DPDVG NSLQ Y+L+ N YF+L VQ+  D  KY
Sbjct: 132 SFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKY 191

Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
            ELVLERALDRE E    LVLTA DGG P  S +  I I ++D NDNAPVF Q  Y   V
Sbjct: 192 PELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSV 251

Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
            E+ P GTR++ V ATD DEG NG++ YSF    R  + QLF L+ ++G +TI G LD+E
Sbjct: 252 RENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYE 310

Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
           D+  ++I ++A D       A  KVLV V+D NDNAPE+TVTS+ S V E +  GTVIAL
Sbjct: 311 DSGFYDIDVEAHD--GPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIAL 368

Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
            +V D D+G NGLVTC +P  LPF+L  +  NY+ L T   LDRE V EYN+++TA D G
Sbjct: 369 FNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQG 428

Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
           TP LS  T + +QV DINDNPP    +SY  YI ENN  GA IL+++  DPD+  NAR++
Sbjct: 429 TPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARIT 488

Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
           + L E   +   +  Y +IN + GI+ +L   DYE  R+ +L    SD G P L++N+S+
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSL 548

Query: 554 NIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
           ++FV D+NDN P++LY   P  G + VE+ PR   +G+LV++VV  D D+G NAWLSYSL
Sbjct: 549 SLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSL 608

Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
           L S    LFA+GLHTG++ TAR + D D+ +Q L V+++D+G+P LS T TLTV+V +  
Sbjct: 609 LKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSI 668

Query: 671 PEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRA 729
           P+  A+  S     +     LT YL++++  VS  F+  V  ++  K+ +W +SR L  A
Sbjct: 669 PDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSR-LLHA 727

Query: 730 PVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNT 788
             S L   P    +  D VR  L +    H+V LT DSR+S  +  +P  A  L SR++ 
Sbjct: 728 EGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFSQPSYADTLISRESC 785

Query: 789 LRSCDPVFYRQVL-------GAESAPPG-QVRFSKS 816
            +S +P+   Q L         + APP    RFS++
Sbjct: 786 EKS-EPLLITQDLLETKGDPNLQQAPPNTDWRFSQA 820


>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  629 bits (1621), Expect = e-180
 Identities = 355/803 (44%), Positives = 498/803 (62%), Gaps = 12/803 (1%)

Query: 15  RVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
           R++ + LLLG L +  +  I Y + EE+E+G  VGN+  +LGL    L+ R  R+VS   
Sbjct: 12  RLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGR 71

Query: 74  RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
            + F +N  +G +    R+DREELC   P+C   LE+++E+ +++  VEV I D+NDN P
Sbjct: 72  TQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPP 131

Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
           +F T++ +++++E   PG RFPL  A DPDVG NSLQ Y+L+ N YF+L VQ+  D  KY
Sbjct: 132 SFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKY 191

Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
            ELVLERALDRE E    LVLTA DGG P  S +  I I ++D NDNAPVF Q  Y   V
Sbjct: 192 PELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSV 251

Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
            E+ P GTR++ V ATD DEG NG++ YSF    R  + QLF L+ ++G +TI G LD+E
Sbjct: 252 RENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYE 310

Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
           D+  ++I ++A D       A  KVLV V+D NDNAPE+TVTS+ S V E +  GTVIAL
Sbjct: 311 DSGFYDIDVEAHD--GPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIAL 368

Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
            +V D D+G NGLVTC +P  LPF+L  +  NY+ L T   LDRE V EYN+++TA D G
Sbjct: 369 FNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQG 428

Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
           TP LS  T + +QV DINDNPP    +SY  YI ENN  GA IL+++  DPD+  NAR++
Sbjct: 429 TPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARIT 488

Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
           + L E   +   +  Y +IN + GI+ +L   DYE  R+ +L    SD G P L++N+S+
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSL 548

Query: 554 NIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
           ++FV D+NDN P++LY   P  G + VE+ PR   +G+LV++VV  D D+G NAWLSYSL
Sbjct: 549 SLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSL 608

Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
           L S    LFA+GLHTG++ TAR + D D+ +Q L V+++D+G+P LS T TLTV+V +  
Sbjct: 609 LKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSI 668

Query: 671 PEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRA 729
           P+  A+  S     +     LT YL++++  VS  F+  V  ++  K+ +W +SR L  A
Sbjct: 669 PDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSR-LLHA 727

Query: 730 PVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNT 788
             S L   P    +  D VR  L +    H+V LT DSR+S  +  +P  A  L SR++ 
Sbjct: 728 EGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFSQPSYADTLISRESC 785

Query: 789 LRSCDPVFYRQVLGAESAPPGQV 811
            +S   +  + +L  +  P  QV
Sbjct: 786 EKSEPLLITQDLLETKGDPNLQV 808


>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score =  624 bits (1609), Expect = e-178
 Identities = 347/802 (43%), Positives = 494/802 (61%), Gaps = 13/802 (1%)

Query: 19  VLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFF 77
           +L LLG L   A+  I Y IPEE EKG  VGN+V +LGL+   L+    R+VS    + F
Sbjct: 16  LLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLF 75

Query: 78  EVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPT 137
            +N   G +    R+DREELC   P C V+  ++VE+ L L+ VEV I DINDN P F  
Sbjct: 76  SLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLK 135

Query: 138 QEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELV 197
           +E++++I E  AP +RFPL   +DPDVG NSLQ ++LS N +F++ VQ+     KY ELV
Sbjct: 136 EELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELV 195

Query: 198 LERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDA 257
           LE  LDRE E   +LVLTA+DGG P  S+   I + VLD NDN P+F Q +YR  V E+ 
Sbjct: 196 LEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENL 255

Query: 258 PSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKL 317
           P GT V+ V ATD DEG +GE+ YSF       + Q+F L+++TG ++    LD+ED+  
Sbjct: 256 PVGTPVLAVTATDQDEGVHGEVTYSFVKITEK-ISQIFCLNVLTGEISTSANLDYEDSSF 314

Query: 318 HEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVT 377
           +E+ ++A+D     + A  KVL+ ++DVNDN PE+ VTS    + E AP GTVIAL  V 
Sbjct: 315 YELGVEARDGPGLRDRA--KVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVF 372

Query: 378 DLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSL 437
           D D+G NGLVTC +P  LPF L  S+ NY+ L T+A LDRE V  YN+++TA D GTP L
Sbjct: 373 DRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPL 432

Query: 438 SALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLL 497
           S  TI+ + V+D NDNPP    SSY VY+ ENN  GA I +++  DPD  QNA++S+ L 
Sbjct: 433 STETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLA 492

Query: 498 EQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFV 557
           E   +   +  Y +IN D GI+ +L   DYE  R+ +L    SD G P L++N+S+++FV
Sbjct: 493 EDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFV 552

Query: 558 TDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
            D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY LL + 
Sbjct: 553 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 612

Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
              LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +  P+  
Sbjct: 613 EPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDIL 672

Query: 675 AEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSS 733
           A+  S   + +    +LT YL++++  VS  F+  V  ++  ++ +W +SR L +A    
Sbjct: 673 ADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSR-LLQASGGG 731

Query: 734 LYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSC 792
           L   PG   +  + VR  L +    H+V LT DSR+S  +  +P  A  L ++++  +S 
Sbjct: 732 LASMPGSHFVGVEGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKS- 788

Query: 793 DPVFYRQVLGAESAPPGQVRFS 814
           +P+   Q L      P Q++ S
Sbjct: 789 EPLLITQDLLETKGEPRQLQVS 810


>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  623 bits (1606), Expect = e-178
 Identities = 346/800 (43%), Positives = 493/800 (61%), Gaps = 13/800 (1%)

Query: 19  VLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFF 77
           +L LLG L   A+  I Y IPEE EKG  VGN+V +LGL+   L+    R+VS    + F
Sbjct: 16  LLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLF 75

Query: 78  EVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPT 137
            +N   G +    R+DREELC   P C V+  ++VE+ L L+ VEV I DINDN P F  
Sbjct: 76  SLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLK 135

Query: 138 QEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELV 197
           +E++++I E  AP +RFPL   +DPDVG NSLQ ++LS N +F++ VQ+     KY ELV
Sbjct: 136 EELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELV 195

Query: 198 LERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDA 257
           LE  LDRE E   +LVLTA+DGG P  S+   I + VLD NDN P+F Q +YR  V E+ 
Sbjct: 196 LEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENL 255

Query: 258 PSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKL 317
           P GT V+ V ATD DEG +GE+ YSF       + Q+F L+++TG ++    LD+ED+  
Sbjct: 256 PVGTPVLAVTATDQDEGVHGEVTYSFVKITEK-ISQIFCLNVLTGEISTSANLDYEDSSF 314

Query: 318 HEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVT 377
           +E+ ++A+D     + A  KVL+ ++DVNDN PE+ VTS    + E AP GTVIAL  V 
Sbjct: 315 YELGVEARDGPGLRDRA--KVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVF 372

Query: 378 DLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSL 437
           D D+G NGLVTC +P  LPF L  S+ NY+ L T+A LDRE V  YN+++TA D GTP L
Sbjct: 373 DRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPL 432

Query: 438 SALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLL 497
           S  TI+ + V+D NDNPP    SSY VY+ ENN  GA I +++  DPD  QNA++S+ L 
Sbjct: 433 STETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLA 492

Query: 498 EQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFV 557
           E   +   +  Y +IN D GI+ +L   DYE  R+ +L    SD G P L++N+S+++FV
Sbjct: 493 EDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFV 552

Query: 558 TDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
            D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY LL + 
Sbjct: 553 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 612

Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
              LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +  P+  
Sbjct: 613 EPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDIL 672

Query: 675 AEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSS 733
           A+  S   + +    +LT YL++++  VS  F+  V  ++  ++ +W +SR L +A    
Sbjct: 673 ADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSR-LLQASGGG 731

Query: 734 LYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSC 792
           L   PG   +  + VR  L +    H+V LT DSR+S  +  +P  A  L ++++  +S 
Sbjct: 732 LASMPGSHFVGVEGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKS- 788

Query: 793 DPVFYRQVLGAESAPPGQVR 812
           +P+   Q L      P Q++
Sbjct: 789 EPLLITQDLLETKGEPRQLQ 808


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score =  619 bits (1595), Expect = e-177
 Identities = 344/790 (43%), Positives = 497/790 (62%), Gaps = 16/790 (2%)

Query: 33  IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
           I Y +PEE EKG  VGN+  +LGL+   L+ R  R+VS    + F VN  +G +    R+
Sbjct: 32  IRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRI 91

Query: 93  DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
           DREELC T+ SC + +EL+VE+ L+++ VEV I DINDN P+F   E+++++SE   PG 
Sbjct: 92  DREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGA 151

Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
           RF L +A DPDVG NSLQ+Y+LS N YF+L+++ R D  K  ELVLE +LDRE+E +  L
Sbjct: 152 RFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLL 211

Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
           +LTALDGG P    ++PI + VLD ND+ P+F QS+YR  V E+  SGTRV+ V ATD D
Sbjct: 212 LLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPD 271

Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
           EG NGE++YSF  +  +   ++F LD  TG + ++G LDFE  + +E+ IQ +D G    
Sbjct: 272 EGINGEVMYSF-RNMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGG--L 328

Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
                +L+ VVDVNDNAPEIT+TS  + + E++P GTVIALL+V D D+GENG V+C +P
Sbjct: 329 FTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIP 388

Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
             LPF L  +  NY+ L TS  LDRE V  YN+++TA D G+P LSA T V + V+D ND
Sbjct: 389 NHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDND 448

Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
           NPP    SSY  YI ENN  GA I +++  DPD+ QNA +++ L +   +   +  Y +I
Sbjct: 449 NPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI 508

Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
           N + G++ +L   DYE  R+ EL     D G P L++N+S+++FV D+NDNAP++LY   
Sbjct: 509 NSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 568

Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
           P  G + VE+ PR    G+LV++VV  D D+G NAWLSY LL +    LFA+G HTG++ 
Sbjct: 569 PTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 628

Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPS-GSAPREQKK 688
           TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +  PE  A+  S  S    +  
Sbjct: 629 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETS 688

Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTP-GPSLHADAV 747
           +L+ YL++++  VS  F+V V  ++  ++++W +SR L +A    L   P    +  D V
Sbjct: 689 DLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSR-LLQASEGGLAGMPTSHFVGVDGV 747

Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQ----VLGA 803
           +  L +    H+V L  DS++S  +  +P     L S+++  +S +P+   +    +LG 
Sbjct: 748 QAFLQT--YSHEVSLIADSQKSHLIFPQPNYGDTLISQESCEKS-EPLLIAEDSAIILGK 804

Query: 804 ESAPPGQVRF 813
                 QVRF
Sbjct: 805 CDPTSNQVRF 814


>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  619 bits (1595), Expect = e-177
 Identities = 334/781 (42%), Positives = 490/781 (62%), Gaps = 14/781 (1%)

Query: 14  GRVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
           GR+V +  LLG L +A ++ I Y +PEE EKG+ VGN+  +L L+   L+ RR R+VS  
Sbjct: 11  GRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRG 70

Query: 73  SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
             + F +N  +G +    R+DREELC   P C V  +++VE+ ++L+ +E+ + DIND+ 
Sbjct: 71  RTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130

Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
           P F  + ++++I+E   PG R+PL  A DPDVG NSLQ+Y+LS N +F+L VQT ++   
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190

Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
             ELVLERALDRE   +  LVLTA DGG P  S+++ IH+ VLD NDNAPVF Q +YR +
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250

Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
           VLE+ P GT ++   A+DLDEG NG++ Y F   N      LF L+  TG ++    LD+
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEK-QSLLFQLNENTGEISTAKSLDY 309

Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
           E+   +E+ IQA+D G        KVL+ V DVNDN PE+T+TS++SPV EDAP GTVI 
Sbjct: 310 EECSFYEMEIQAEDGGGLK--GWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367

Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
           L +  D D+G+NG V C +   L F+L +S ++Y+ L T+  LDRE   EYN+++TA D 
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427

Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
           GTP LS    + +QV+DINDNPP  SQ+SY VY+ ENN  G  I ++  +DPD+ +N+R+
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487

Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
            + L E   +   +  Y +IN D G++ +L   DYE  R+ ++    SD G+P L++N+S
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547

Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
           + +FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY 
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
           L  +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV++ + 
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667

Query: 670 SPEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
            P+  A+  S   P + +  +LT YL++++ +VS  F+  V  ++  ++  W  S  L R
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWHSSH-LLR 726

Query: 729 APVSSLYRTP-GPSLHADAVRGGLMSPHLYHQVY-LTTDSRRSDPLLKKPGAASPLASRQ 786
           A    L   P    +  D VR  L +   Y Q + LT DSR+S  +  +P  A  L S+Q
Sbjct: 727 ATSDGLAGVPTSHFVGVDGVRAFLQT---YSQEFSLTADSRKSHLIFPQPNYADTLISQQ 783

Query: 787 N 787
           +
Sbjct: 784 S 784


>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
           [Homo sapiens]
          Length = 828

 Score =  619 bits (1595), Expect = e-177
 Identities = 334/781 (42%), Positives = 490/781 (62%), Gaps = 14/781 (1%)

Query: 14  GRVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
           GR+V +  LLG L +A ++ I Y +PEE EKG+ VGN+  +L L+   L+ RR R+VS  
Sbjct: 11  GRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRG 70

Query: 73  SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
             + F +N  +G +    R+DREELC   P C V  +++VE+ ++L+ +E+ + DIND+ 
Sbjct: 71  RTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130

Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
           P F  + ++++I+E   PG R+PL  A DPDVG NSLQ+Y+LS N +F+L VQT ++   
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190

Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
             ELVLERALDRE   +  LVLTA DGG P  S+++ IH+ VLD NDNAPVF Q +YR +
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250

Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
           VLE+ P GT ++   A+DLDEG NG++ Y F   N      LF L+  TG ++    LD+
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEK-QSLLFQLNENTGEISTAKSLDY 309

Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
           E+   +E+ IQA+D G        KVL+ V DVNDN PE+T+TS++SPV EDAP GTVI 
Sbjct: 310 EECSFYEMEIQAEDGGGLK--GWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367

Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
           L +  D D+G+NG V C +   L F+L +S ++Y+ L T+  LDRE   EYN+++TA D 
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427

Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
           GTP LS    + +QV+DINDNPP  SQ+SY VY+ ENN  G  I ++  +DPD+ +N+R+
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487

Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
            + L E   +   +  Y +IN D G++ +L   DYE  R+ ++    SD G+P L++N+S
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547

Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
           + +FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY 
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
           L  +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV++ + 
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667

Query: 670 SPEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
            P+  A+  S   P + +  +LT YL++++ +VS  F+  V  ++  ++  W  S  L R
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWHSSH-LLR 726

Query: 729 APVSSLYRTP-GPSLHADAVRGGLMSPHLYHQVY-LTTDSRRSDPLLKKPGAASPLASRQ 786
           A    L   P    +  D VR  L +   Y Q + LT DSR+S  +  +P  A  L S+Q
Sbjct: 727 ATSDGLAGVPTSHFVGVDGVRAFLQT---YSQEFSLTADSRKSHLIFPQPNYADTLISQQ 783

Query: 787 N 787
           +
Sbjct: 784 S 784


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  618 bits (1594), Expect = e-177
 Identities = 340/768 (44%), Positives = 483/768 (62%), Gaps = 12/768 (1%)

Query: 33  IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
           I Y IPEE EKG  VGN+  +LGL    L+ R  R+VS    + F +N  +G +    R+
Sbjct: 35  ISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRI 94

Query: 93  DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
           DREELC     C V+  ++VE+ ++LF +E+ + DINDN P F  + + ++I+E VA G 
Sbjct: 95  DREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGM 154

Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
           RFPL  A DPDVG NSLQ+Y+LS N++F+LRVQ+R +  KY ELVLE +LDRE E    L
Sbjct: 155 RFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHL 214

Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
           VLTA DGG P  S ++ + + V DANDNAPVF    YR  V E+ P GT+++ V ATD D
Sbjct: 215 VLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRD 274

Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
           EG NGE+ YSF       + + F L+  TG + I   LD+E+T  +EI IQA+D GA   
Sbjct: 275 EGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYL- 332

Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
            A  KVL+ V DVNDN+PE+T+TS++SPV ED+PLGTV+ALL+V DLD+ +NG VTC + 
Sbjct: 333 -ATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL 391

Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
             LPF L  S+ +Y+ L     LDRE V  YN+++TA D G+P LS      +QV+DIND
Sbjct: 392 AYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADIND 451

Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
           NPP  SQ SY  YI ENN  GA I +++  DPD+ +NA++ + L E   +   +  Y +I
Sbjct: 452 NPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISI 511

Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
           N D G++ +L   DYE   E ++    SD G P L++N+S+++FV D+NDNAP++LY   
Sbjct: 512 NSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 571

Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
           P  G + VE+ PR    G+LV++VV  D D+G NAWLSY LL +    LFA+G HTG++ 
Sbjct: 572 PTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 631

Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAP-REQKK 688
           TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +  P+  A+  S  +P   +  
Sbjct: 632 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETS 691

Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADAV 747
           +LT YL++++  VS  F+  V  ++  ++ +W +SR L +A    L    G   +  D V
Sbjct: 692 DLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSR-LLQASGGGLTGVSGSHFVGVDGV 750

Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPV 795
           R  L +    H+V LT DSR+S  +  +P  A  L S+++  ++ DP+
Sbjct: 751 RAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKN-DPL 795


>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
           [Homo sapiens]
          Length = 850

 Score =  618 bits (1594), Expect = e-177
 Identities = 340/768 (44%), Positives = 483/768 (62%), Gaps = 12/768 (1%)

Query: 33  IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
           I Y IPEE EKG  VGN+  +LGL    L+ R  R+VS    + F +N  +G +    R+
Sbjct: 35  ISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRI 94

Query: 93  DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
           DREELC     C V+  ++VE+ ++LF +E+ + DINDN P F  + + ++I+E VA G 
Sbjct: 95  DREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGM 154

Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
           RFPL  A DPDVG NSLQ+Y+LS N++F+LRVQ+R +  KY ELVLE +LDRE E    L
Sbjct: 155 RFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHL 214

Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
           VLTA DGG P  S ++ + + V DANDNAPVF    YR  V E+ P GT+++ V ATD D
Sbjct: 215 VLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRD 274

Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
           EG NGE+ YSF       + + F L+  TG + I   LD+E+T  +EI IQA+D GA   
Sbjct: 275 EGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYL- 332

Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
            A  KVL+ V DVNDN+PE+T+TS++SPV ED+PLGTV+ALL+V DLD+ +NG VTC + 
Sbjct: 333 -ATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL 391

Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
             LPF L  S+ +Y+ L     LDRE V  YN+++TA D G+P LS      +QV+DIND
Sbjct: 392 AYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADIND 451

Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
           NPP  SQ SY  YI ENN  GA I +++  DPD+ +NA++ + L E   +   +  Y +I
Sbjct: 452 NPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISI 511

Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
           N D G++ +L   DYE   E ++    SD G P L++N+S+++FV D+NDNAP++LY   
Sbjct: 512 NSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 571

Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
           P  G + VE+ PR    G+LV++VV  D D+G NAWLSY LL +    LFA+G HTG++ 
Sbjct: 572 PTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 631

Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAP-REQKK 688
           TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +  P+  A+  S  +P   +  
Sbjct: 632 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETS 691

Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADAV 747
           +LT YL++++  VS  F+  V  ++  ++ +W +SR L +A    L    G   +  D V
Sbjct: 692 DLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSR-LLQASGGGLTGVSGSHFVGVDGV 750

Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPV 795
           R  L +    H+V LT DSR+S  +  +P  A  L S+++  ++ DP+
Sbjct: 751 RAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKN-DPL 795


>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  618 bits (1594), Expect = e-177
 Identities = 345/795 (43%), Positives = 497/795 (62%), Gaps = 14/795 (1%)

Query: 14  GRVVGVLL-LLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSG 71
           GR + +L  LLG L    S  I Y + EE +KG  VGN+  +LGL+   L+ R  R+VS 
Sbjct: 10  GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69

Query: 72  ASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDN 131
              + F +N ++G +   +R+DREELC  +P C V + ++VE+ L++F VE+ I+DINDN
Sbjct: 70  GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129

Query: 132 NPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDST 191
            P FPT+E++++I E   PGTRFP+++A DPDVG NSLQ Y+LS N+YF+L V +  +  
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189

Query: 192 KYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRA 251
           KY ELVLERALDRE++   QLVL A DGG P  S +L I + VLDANDN P+F Q  YR 
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249

Query: 252 RVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLD 311
            V E+ P GTR++ V ATD DEG N ++ Y         + ++F L+ V+G ++I   LD
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308

Query: 312 FEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVI 371
           +ED   +EI I+A+D       A  K+LV V+DVNDNAPEIT+TS+ S VPE+  +G  I
Sbjct: 309 YEDAMFYEIKIEAQDGPGLLSRA--KILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366

Query: 372 ALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARD 431
           AL+ V D D+G+NG V   V   LPF L  S+  Y+ L T+  LDRE + EYN+S+ A D
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426

Query: 432 AGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNAR 491
            G+P LS  T + + V DINDNPP     SY  YI ENN  GA I +++  DPD+  NAR
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486

Query: 492 LSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNI 551
           +++ L E   +   +  + +IN + G++ +L   DYE  R+ +L    SD G P L++N+
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546

Query: 552 SVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSY 608
           S+N+FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606

Query: 609 SLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE 668
            LL +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666

Query: 669 DSPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLY 727
             P+  A+  S   + +    +LT YL++++  VS  F+  V  ++  ++ +W +SR L 
Sbjct: 667 RIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSR-LL 725

Query: 728 RAPVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQ 786
           +A    L  TPG   + AD VR  L +    H+V LT DSR+S  +  +P  A  L S++
Sbjct: 726 QASGGGLASTPGSHFVGADGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQE 783

Query: 787 NTLRSCDPVFYRQVL 801
           +  +S +P+   Q L
Sbjct: 784 SCEKS-EPLLITQDL 797


>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 829

 Score =  618 bits (1594), Expect = e-177
 Identities = 345/795 (43%), Positives = 497/795 (62%), Gaps = 14/795 (1%)

Query: 14  GRVVGVLL-LLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSG 71
           GR + +L  LLG L    S  I Y + EE +KG  VGN+  +LGL+   L+ R  R+VS 
Sbjct: 10  GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69

Query: 72  ASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDN 131
              + F +N ++G +   +R+DREELC  +P C V + ++VE+ L++F VE+ I+DINDN
Sbjct: 70  GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129

Query: 132 NPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDST 191
            P FPT+E++++I E   PGTRFP+++A DPDVG NSLQ Y+LS N+YF+L V +  +  
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189

Query: 192 KYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRA 251
           KY ELVLERALDRE++   QLVL A DGG P  S +L I + VLDANDN P+F Q  YR 
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249

Query: 252 RVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLD 311
            V E+ P GTR++ V ATD DEG N ++ Y         + ++F L+ V+G ++I   LD
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308

Query: 312 FEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVI 371
           +ED   +EI I+A+D       A  K+LV V+DVNDNAPEIT+TS+ S VPE+  +G  I
Sbjct: 309 YEDAMFYEIKIEAQDGPGLLSRA--KILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366

Query: 372 ALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARD 431
           AL+ V D D+G+NG V   V   LPF L  S+  Y+ L T+  LDRE + EYN+S+ A D
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426

Query: 432 AGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNAR 491
            G+P LS  T + + V DINDNPP     SY  YI ENN  GA I +++  DPD+  NAR
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486

Query: 492 LSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNI 551
           +++ L E   +   +  + +IN + G++ +L   DYE  R+ +L    SD G P L++N+
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546

Query: 552 SVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSY 608
           S+N+FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606

Query: 609 SLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE 668
            LL +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666

Query: 669 DSPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLY 727
             P+  A+  S   + +    +LT YL++++  VS  F+  V  ++  ++ +W +SR L 
Sbjct: 667 RIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSR-LL 725

Query: 728 RAPVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQ 786
           +A    L  TPG   + AD VR  L +    H+V LT DSR+S  +  +P  A  L S++
Sbjct: 726 QASGGGLASTPGSHFVGADGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQE 783

Query: 787 NTLRSCDPVFYRQVL 801
           +  +S +P+   Q L
Sbjct: 784 SCEKS-EPLLITQDL 797


>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
           [Homo sapiens]
          Length = 935

 Score =  616 bits (1588), Expect = e-176
 Identities = 347/805 (43%), Positives = 499/805 (61%), Gaps = 33/805 (4%)

Query: 33  IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
           I Y +PEE EKG  VGN+  +LGL+   L+ R  R+VS    + F VN  +G +    R+
Sbjct: 32  IRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRI 91

Query: 93  DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
           DREELC T+ SC + +EL+VE+ L+++ VEV I DINDN P+F   E+++++SE   PG 
Sbjct: 92  DREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGA 151

Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
           RF L +A DPDVG NSLQ+Y+LS N YF+L+++ R D  K  ELVLE +LDRE+E +  L
Sbjct: 152 RFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLL 211

Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
           +LTALDGG P    ++PI + VLD ND+ P+F QS+YR  V E+  SGTRV+ V ATD D
Sbjct: 212 LLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPD 271

Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
           EG NGE++YSF  +  +   ++F LD  TG + ++G LDFE  + +E+ IQ +D G    
Sbjct: 272 EGINGEVMYSF-RNMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGG--L 328

Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
                +L+ VVDVNDNAPEIT+TS  + + E++P GTVIALL+V D D+GENG V+C +P
Sbjct: 329 FTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIP 388

Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
             LPF L  +  NY+ L TS  LDRE V  YN+++TA D G+P LSA T V + V+D ND
Sbjct: 389 NHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDND 448

Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
           NPP    SSY  YI ENN  GA I +++  DPD+ QNA +++ L +   +   +  Y +I
Sbjct: 449 NPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI 508

Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
           N + G++ +L   DYE  R+ EL     D G P L++N+S+++FV D+NDNAP++LY   
Sbjct: 509 NSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 568

Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
           P  G + VE+ PR    G+LV++VV  D D+G NAWLSY LL +    LFA+G HTG++ 
Sbjct: 569 PTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 628

Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPS-GSAPREQKK 688
           TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +  PE  A+  S  S    +  
Sbjct: 629 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETS 688

Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTP-GPSLHADAV 747
           +L+ YL++++  VS  F+V V  ++  ++++W +SR L +A    L   P    +  D V
Sbjct: 689 DLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSR-LLQASEGGLAGMPTSHFVGVDGV 747

Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS---------------C 792
           +  L +    H+V L  DS++S  +  +P     L S+++  +S               C
Sbjct: 748 QAFLQT--YSHEVSLIADSQKSHLIFPQPNYGDTLISQESCEKSEPLLIAEDSAIILGKC 805

Query: 793 DPVFYRQVLGAESAPPG-QVRFSKS 816
           DP   +Q      APP    RFS++
Sbjct: 806 DPTSNQQ------APPNTDWRFSQA 824


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  614 bits (1584), Expect = e-176
 Identities = 319/698 (45%), Positives = 453/698 (64%), Gaps = 8/698 (1%)

Query: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
           LLLL A    S  +HY + EE + G  VG +  +LGL+L  L  R FRV S       EV
Sbjct: 18  LLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEV 77

Query: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
           N + G +FVN R+DREELCG    C++ LE++V+ PL++F VEV ++DINDN P FP   
Sbjct: 78  NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAV 137

Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
             L ISE+  PG+RF LE A D D+G+NSL TY L   EYF L V+  ++  K   LVL+
Sbjct: 138 KNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLK 197

Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
           + L+RE  P   L++TA+DGG P L+ +  + I VLD NDNAP F +++Y+ R+LE+AP+
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257

Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
           GT VV V ATDLDEG N +I YSF +   A +   F LD V G +++KG +DFE++K +E
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317

Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
           I ++A DKG  P   HC VL+E+VD+NDN PE+ + S+  PV ED+PL TVIAL+SV+D 
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377

Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
           D+G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+PSL A
Sbjct: 378 DSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWA 437

Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
              V V+V+D+NDN P  SQS Y V+++ENN PG  I  +S  D DA +NA +S+ L+E+
Sbjct: 438 TASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497

Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557

Query: 560 RNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
            NDNAP +L PR    GG+  E++PR   AGH+V++V   DAD+G+NAWLSY L      
Sbjct: 558 ENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGG 617

Query: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
           +   F +GL+TG+IST R + + D+PR  L VL+KD+GEPSL+ TAT+ VS+ E   +P+
Sbjct: 618 ARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677

Query: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
           A ++  +G + P     ++  YL++++  VS   V+T+
Sbjct: 678 ASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTL 715


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score =  614 bits (1584), Expect = e-176
 Identities = 319/698 (45%), Positives = 453/698 (64%), Gaps = 8/698 (1%)

Query: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
           LLLL A    S  +HY + EE + G  VG +  +LGL+L  L  R FRV S       EV
Sbjct: 18  LLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEV 77

Query: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
           N + G +FVN R+DREELCG    C++ LE++V+ PL++F VEV ++DINDN P FP   
Sbjct: 78  NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAV 137

Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
             L ISE+  PG+RF LE A D D+G+NSL TY L   EYF L V+  ++  K   LVL+
Sbjct: 138 KNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLK 197

Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
           + L+RE  P   L++TA+DGG P L+ +  + I VLD NDNAP F +++Y+ R+LE+AP+
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257

Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
           GT VV V ATDLDEG N +I YSF +   A +   F LD V G +++KG +DFE++K +E
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317

Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
           I ++A DKG  P   HC VL+E+VD+NDN PE+ + S+  PV ED+PL TVIAL+SV+D 
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377

Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
           D+G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+PSL A
Sbjct: 378 DSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWA 437

Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
              V V+V+D+NDN P  SQS Y V+++ENN PG  I  +S  D DA +NA +S+ L+E+
Sbjct: 438 TASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497

Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557

Query: 560 RNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
            NDNAP +L PR    GG+  E++PR   AGH+V++V   DAD+G+NAWLSY L      
Sbjct: 558 ENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGG 617

Query: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
           +   F +GL+TG+IST R + + D+PR  L VL+KD+GEPSL+ TAT+ VS+ E   +P+
Sbjct: 618 ARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677

Query: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
           A ++  +G + P     ++  YL++++  VS   V+T+
Sbjct: 678 ASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTL 715


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score =  610 bits (1574), Expect = e-174
 Identities = 321/712 (45%), Positives = 457/712 (64%), Gaps = 9/712 (1%)

Query: 6   WRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARR 65
           WR G + + R++ +LLLL A    S  +HY +PEE + G  VG +  +LGL+L  L  R 
Sbjct: 5   WR-GELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63

Query: 66  FRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVI 125
           FRV S   R   EV+ + G +FVN R+DREELCG    C++ LE++V+ PL++F V+V +
Sbjct: 64  FRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV 123

Query: 126 QDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQ 185
           +D+NDN P F  ++ KL +SE+  P +RFPLE A D DVG+NS+ TY LS ++YF L V 
Sbjct: 124 KDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVN 183

Query: 186 TREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFN 245
           ++ D  K  ELVL ++LDRE  P+  L LTA DGG P L+ ++ + + VLD NDNAP F 
Sbjct: 184 SKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFE 243

Query: 246 QSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLT 305
           QS Y  R+ E+A +GT V+++ A+D DEG NG I YSF S     V   F++D  TG + 
Sbjct: 244 QSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIV 303

Query: 306 IKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDA 365
           I+G LDFE   L++I I A DKG  P   HC VLV ++D NDN PEI +TS+  PV EDA
Sbjct: 304 IRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDA 363

Query: 366 PLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNL 425
             GTVIAL+SV DLD+G NG VTC + P +PF L S+ KNY++L   + LDRE V  Y L
Sbjct: 364 QFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYEL 423

Query: 426 SITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPD 485
            +TARD G+PSL A   + V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D D
Sbjct: 424 VVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483

Query: 486 APQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTP 545
           A +NA +S+ L+E+      +  Y +++ ++G V +L PLD+E+    +      D G P
Sbjct: 484 AQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVP 543

Query: 546 VLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGH 602
            L +N+++ +FV D NDNAP +L PR    GG++ +++PR   AGH+V++V   DAD+G+
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGY 603

Query: 603 NAWLSYSL--LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
           NAWLSY L    S  +  F +GL+TG+IST R + + DSPR  L VL+KD+GEP+L+ TA
Sbjct: 604 NAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATA 663

Query: 661 TLTVSVTE--DSPEARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
           T+ VS+ E   +P+A +   +G   P     ++  YL++++  VS   V+T+
Sbjct: 664 TVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTL 715


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  610 bits (1574), Expect = e-174
 Identities = 321/712 (45%), Positives = 457/712 (64%), Gaps = 9/712 (1%)

Query: 6   WRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARR 65
           WR G + + R++ +LLLL A    S  +HY +PEE + G  VG +  +LGL+L  L  R 
Sbjct: 5   WR-GELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63

Query: 66  FRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVI 125
           FRV S   R   EV+ + G +FVN R+DREELCG    C++ LE++V+ PL++F V+V +
Sbjct: 64  FRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV 123

Query: 126 QDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQ 185
           +D+NDN P F  ++ KL +SE+  P +RFPLE A D DVG+NS+ TY LS ++YF L V 
Sbjct: 124 KDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVN 183

Query: 186 TREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFN 245
           ++ D  K  ELVL ++LDRE  P+  L LTA DGG P L+ ++ + + VLD NDNAP F 
Sbjct: 184 SKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFE 243

Query: 246 QSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLT 305
           QS Y  R+ E+A +GT V+++ A+D DEG NG I YSF S     V   F++D  TG + 
Sbjct: 244 QSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIV 303

Query: 306 IKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDA 365
           I+G LDFE   L++I I A DKG  P   HC VLV ++D NDN PEI +TS+  PV EDA
Sbjct: 304 IRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDA 363

Query: 366 PLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNL 425
             GTVIAL+SV DLD+G NG VTC + P +PF L S+ KNY++L   + LDRE V  Y L
Sbjct: 364 QFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYEL 423

Query: 426 SITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPD 485
            +TARD G+PSL A   + V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D D
Sbjct: 424 VVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483

Query: 486 APQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTP 545
           A +NA +S+ L+E+      +  Y +++ ++G V +L PLD+E+    +      D G P
Sbjct: 484 AQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVP 543

Query: 546 VLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGH 602
            L +N+++ +FV D NDNAP +L PR    GG++ +++PR   AGH+V++V   DAD+G+
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGY 603

Query: 603 NAWLSYSL--LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
           NAWLSY L    S  +  F +GL+TG+IST R + + DSPR  L VL+KD+GEP+L+ TA
Sbjct: 604 NAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATA 663

Query: 661 TLTVSVTE--DSPEARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
           T+ VS+ E   +P+A +   +G   P     ++  YL++++  VS   V+T+
Sbjct: 664 TVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTL 715


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  610 bits (1572), Expect = e-174
 Identities = 346/821 (42%), Positives = 501/821 (61%), Gaps = 24/821 (2%)

Query: 9   GLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV 68
           GLV  G ++G L   G      T I Y +PEE EKG  VG++  +LGL+   L+ R  R+
Sbjct: 12  GLVLLGILLGTLWETGC-----TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRI 66

Query: 69  VSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDI 128
           +     + F +N  +G +    R+DREELC     C + L++++E+ ++++ VEV ++DI
Sbjct: 67  IPRGRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDI 126

Query: 129 NDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTRE 188
           NDN P F   E++++ISE  A   RFPL  A DPD+G NSLQ+YELS N +F+L VQ   
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGA 186

Query: 189 DSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSL 248
           D +KY ELVL+RALDRE + +  LVLTA DGG P  + +  I + VLDANDNAP F Q  
Sbjct: 187 DGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPE 246

Query: 249 YRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKG 308
           YRA V E+   GT+++ V ATD DEG N E+ YSF  +      Q+F LD  +G ++  G
Sbjct: 247 YRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIG 305

Query: 309 RLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLG 368
            LD E++  +++ +QA D       A  KVL+ V+DVNDNAPE+ +TS+ S VPE++P G
Sbjct: 306 ELDHEESGFYQMEVQAMDNAG--YSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRG 363

Query: 369 TVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSIT 428
           T+IALL+V D D+ ENG V C +   LPF L  S  NY++L T   LDRE VP YN+++T
Sbjct: 364 TLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVT 423

Query: 429 ARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQ 488
           A D GTP LS  T + + V+D NDNPP   Q+SY  YI ENN  G  +++++  DPD  +
Sbjct: 424 ATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEE 483

Query: 489 NARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLA 548
           NA++++ L E   +   +  Y +IN D G++ +L   DYE  R+ ++     D G P L+
Sbjct: 484 NAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLS 543

Query: 549 TNISVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAW 605
           +N+S+++FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAW
Sbjct: 544 SNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAW 603

Query: 606 LSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVS 665
           LSY LL +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+
Sbjct: 604 LSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 663

Query: 666 VTEDSPEARAEFPSGSAP-REQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSR 724
           V +  P+  A+  S  +P   +  +LT YL++++  VS  F+  V  ++  ++ +W +SR
Sbjct: 664 VADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSR 723

Query: 725 DLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-HQVYLTTDSRRSDPLLKKPGAASPLA 783
            L +A    L  T  P+ H   V G       Y H+V LTTDSR+S  +  +P  A  L 
Sbjct: 724 -LLQASGGGL--TGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLV 780

Query: 784 SRQN------TLRSCDPVFYRQVLG-AESAPPG-QVRFSKS 816
           S+++       L S D VF +   G  E APP    RFS++
Sbjct: 781 SQESFEKSEPLLLSGDSVFSKDSHGLIEQAPPNTDWRFSQA 821


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score =  607 bits (1565), Expect = e-173
 Identities = 314/713 (44%), Positives = 460/713 (64%), Gaps = 9/713 (1%)

Query: 5   AWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSAR 64
           +W SG  S  R++ +LLLL A    +  +HY + EE + G  VG +  +LGL+L  L  R
Sbjct: 4   SWGSGQESR-RLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR 62

Query: 65  RFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVV 124
            FRV S       EVN + G +FVN R+DREELC     C++ LE++V+ PL++F V+V 
Sbjct: 63  LFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVE 122

Query: 125 IQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRV 184
           ++DINDN P FP  +  L I+E+    +RFPLE A D D+G N+L TY LS NEYF+L  
Sbjct: 123 VRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEK 182

Query: 185 QTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVF 244
              ++  K   L+L ++LDRE  P + LVLTA DGG P L+ ++ + I VLDANDNAP F
Sbjct: 183 PPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAF 242

Query: 245 NQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGML 304
           ++++Y+ R+LE+ P+GT V+++ A+DLDEG NG+I+YSF +     V+  F +D +TG +
Sbjct: 243 DRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQI 302

Query: 305 TIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPED 364
            +KG +DFE++K +EI ++  DKG  P   HC+V+VEV D NDN P++   S+  P+ ED
Sbjct: 303 IVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIRED 362

Query: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYN 424
           APLGTVIAL+SV+D D G NGLVTC +   +PF L S+ KNY++L   + LDRE+V  Y 
Sbjct: 363 APLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYE 422

Query: 425 LSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDP 484
           L +TARD G+PSL A   V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S WD 
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482

Query: 485 DAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGT 544
           DA +NA +S+ L+E+      +  Y +++ ++G V +L PLD+E+    +      D G 
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGV 542

Query: 545 PVLATNISVNIFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAG 601
           P L +N+++ +FV D NDNAP +L PR GG+     E++P     GH+V++V   DAD+G
Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSG 602

Query: 602 HNAWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTT 659
           +NAWLSY L      +   F +GL+TG+IST R + +TD+PR  L VL+KD+GEP+L+ T
Sbjct: 603 YNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTAT 662

Query: 660 ATLTVSVTE--DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
           AT+ VS+ E   +P+A +    G+  P     ++  YL++++  VS   V+T+
Sbjct: 663 ATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTL 715


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score =  607 bits (1565), Expect = e-173
 Identities = 314/713 (44%), Positives = 460/713 (64%), Gaps = 9/713 (1%)

Query: 5   AWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSAR 64
           +W SG  S  R++ +LLLL A    +  +HY + EE + G  VG +  +LGL+L  L  R
Sbjct: 4   SWGSGQESR-RLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR 62

Query: 65  RFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVV 124
            FRV S       EVN + G +FVN R+DREELC     C++ LE++V+ PL++F V+V 
Sbjct: 63  LFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVE 122

Query: 125 IQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRV 184
           ++DINDN P FP  +  L I+E+    +RFPLE A D D+G N+L TY LS NEYF+L  
Sbjct: 123 VRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEK 182

Query: 185 QTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVF 244
              ++  K   L+L ++LDRE  P + LVLTA DGG P L+ ++ + I VLDANDNAP F
Sbjct: 183 PPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAF 242

Query: 245 NQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGML 304
           ++++Y+ R+LE+ P+GT V+++ A+DLDEG NG+I+YSF +     V+  F +D +TG +
Sbjct: 243 DRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQI 302

Query: 305 TIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPED 364
            +KG +DFE++K +EI ++  DKG  P   HC+V+VEV D NDN P++   S+  P+ ED
Sbjct: 303 IVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIRED 362

Query: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYN 424
           APLGTVIAL+SV+D D G NGLVTC +   +PF L S+ KNY++L   + LDRE+V  Y 
Sbjct: 363 APLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYE 422

Query: 425 LSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDP 484
           L +TARD G+PSL A   V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S WD 
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482

Query: 485 DAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGT 544
           DA +NA +S+ L+E+      +  Y +++ ++G V +L PLD+E+    +      D G 
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGV 542

Query: 545 PVLATNISVNIFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAG 601
           P L +N+++ +FV D NDNAP +L PR GG+     E++P     GH+V++V   DAD+G
Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSG 602

Query: 602 HNAWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTT 659
           +NAWLSY L      +   F +GL+TG+IST R + +TD+PR  L VL+KD+GEP+L+ T
Sbjct: 603 YNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTAT 662

Query: 660 ATLTVSVTE--DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
           AT+ VS+ E   +P+A +    G+  P     ++  YL++++  VS   V+T+
Sbjct: 663 ATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTL 715


>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  605 bits (1560), Expect = e-173
 Identities = 334/788 (42%), Positives = 487/788 (61%), Gaps = 16/788 (2%)

Query: 9   GLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV 68
           GLV  G ++G L   G      T I Y +PEE EKG  VG++  +LGL+   L+ R  R+
Sbjct: 12  GLVLLGILLGTLWETGC-----TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRI 66

Query: 69  VSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDI 128
           +     + F +N  +G +    R+DREELC     C + L++++E+ ++++ VEV ++DI
Sbjct: 67  IPRGRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDI 126

Query: 129 NDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTRE 188
           NDN P F   E++++ISE  A   RFPL  A DPD+G NSLQ+YELS N +F+L VQ   
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGA 186

Query: 189 DSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSL 248
           D +KY ELVL+RALDRE + +  LVLTA DGG P  + +  I + VLDANDNAP F Q  
Sbjct: 187 DGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPE 246

Query: 249 YRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKG 308
           YRA V E+   GT+++ V ATD DEG N E+ YSF  +      Q+F LD  +G ++  G
Sbjct: 247 YRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIG 305

Query: 309 RLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLG 368
            LD E++  +++ +QA D       A  KVL+ V+DVNDNAPE+ +TS+ S VPE++P G
Sbjct: 306 ELDHEESGFYQMEVQAMDNAG--YSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRG 363

Query: 369 TVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSIT 428
           T+IALL+V D D+ ENG V C +   LPF L  S  NY++L T   LDRE VP YN+++T
Sbjct: 364 TLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVT 423

Query: 429 ARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQ 488
           A D GTP LS  T + + V+D NDNPP   Q+SY  YI ENN  G  +++++  DPD  +
Sbjct: 424 ATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEE 483

Query: 489 NARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLA 548
           NA++++ L E   +   +  Y +IN D G++ +L   DYE  R+ ++     D G P L+
Sbjct: 484 NAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLS 543

Query: 549 TNISVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAW 605
           +N+S+++FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAW
Sbjct: 544 SNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAW 603

Query: 606 LSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVS 665
           LSY LL +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+
Sbjct: 604 LSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 663

Query: 666 VTEDSPEARAEFPSGSAP-REQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSR 724
           V +  P+  A+  S  +P   +  +LT YL++++  VS  F+  V  ++  ++ +W +SR
Sbjct: 664 VADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSR 723

Query: 725 DLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-HQVYLTTDSRRSDPLLKKPGAASPLA 783
            L +A    L  T  P+ H   V G       Y H+V LTTDSR+S  +  +P  A  L 
Sbjct: 724 -LLQASGGGL--TGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLV 780

Query: 784 SRQNTLRS 791
           S+++  +S
Sbjct: 781 SQESFEKS 788


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score =  603 bits (1555), Expect = e-172
 Identities = 316/698 (45%), Positives = 448/698 (64%), Gaps = 8/698 (1%)

Query: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
           +++L A       +HY +PEE + G  VG +  +LGL+L  L  R FR V        EV
Sbjct: 18  IIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDLLEV 77

Query: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
           N + G +FVN R+DREELCG    C++ LE++VE PL++F V+V ++DINDN P FP  +
Sbjct: 78  NLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQ 137

Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
             L I+E+    +RFPLE A D D+G N+L TY LS NEYF L V T     K   LVL 
Sbjct: 138 RNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197

Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
           + LDRE  P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY  ++ E+   
Sbjct: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257

Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
           GT V+   A+DLDEG NG+IIYSF S     ++  F +D ++G +T+ G +DFE+++ H+
Sbjct: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317

Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
           I ++A DKG  P   HC VLVEVVDVNDNAP++T+TS+  P+PEDA  GTVI L+SV D 
Sbjct: 318 IPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDR 377

Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
           D G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+PSL A
Sbjct: 378 DFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437

Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
              V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D DA +NA +S+ L+E 
Sbjct: 438 TASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVEL 497

Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557

Query: 560 RNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL--LGSP 614
            NDNAP +L PR GG+     E++PR   AGH+V++V   DAD+G+NAWLSY L  + + 
Sbjct: 558 ENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAG 617

Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
               F +GL+TG+IST R + +TD+PR  L VL+KD+GEPSL+ TAT+ VS+ E   +P+
Sbjct: 618 ASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677

Query: 673 ARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTV 709
           A +    G A P  +  ++  YL++++  VS   V+T+
Sbjct: 678 ASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTL 715


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score =  603 bits (1555), Expect = e-172
 Identities = 316/698 (45%), Positives = 448/698 (64%), Gaps = 8/698 (1%)

Query: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
           +++L A       +HY +PEE + G  VG +  +LGL+L  L  R FR V        EV
Sbjct: 18  IIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDLLEV 77

Query: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
           N + G +FVN R+DREELCG    C++ LE++VE PL++F V+V ++DINDN P FP  +
Sbjct: 78  NLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQ 137

Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
             L I+E+    +RFPLE A D D+G N+L TY LS NEYF L V T     K   LVL 
Sbjct: 138 RNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197

Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
           + LDRE  P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY  ++ E+   
Sbjct: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257

Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
           GT V+   A+DLDEG NG+IIYSF S     ++  F +D ++G +T+ G +DFE+++ H+
Sbjct: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317

Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
           I ++A DKG  P   HC VLVEVVDVNDNAP++T+TS+  P+PEDA  GTVI L+SV D 
Sbjct: 318 IPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDR 377

Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
           D G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+PSL A
Sbjct: 378 DFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437

Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
              V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D DA +NA +S+ L+E 
Sbjct: 438 TASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVEL 497

Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557

Query: 560 RNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL--LGSP 614
            NDNAP +L PR GG+     E++PR   AGH+V++V   DAD+G+NAWLSY L  + + 
Sbjct: 558 ENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAG 617

Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
               F +GL+TG+IST R + +TD+PR  L VL+KD+GEPSL+ TAT+ VS+ E   +P+
Sbjct: 618 ASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677

Query: 673 ARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTV 709
           A +    G A P  +  ++  YL++++  VS   V+T+
Sbjct: 678 ASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTL 715


>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  603 bits (1555), Expect = e-172
 Identities = 346/818 (42%), Positives = 494/818 (60%), Gaps = 22/818 (2%)

Query: 14  GRVVGVLLLLGALNKAST-VIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
           G ++ +  LLG L +     I Y +PEE +KG  VGN+  +LGLD   L+    R+VS  
Sbjct: 11  GELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRG 70

Query: 73  SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
             + F +N  +G +    R+DREELC   P C + +  +VE+  +LF VE+ I DINDNN
Sbjct: 71  RTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130

Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
           P F  ++++++I+E   PG R+PL  A DPDVG NSLQ+Y+LS N +F+L VQT ++   
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190

Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
             ELVLERALDRE E +  LVLTA DGG P  S+++ IH+ VLD NDNAPVF   +YR +
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250

Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
           VLE+ P GTR++ V A+D DEG NG++ Y F   N      LF L+  TG ++I   LD+
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRKINEKQT-PLFQLNENTGEISIAKSLDY 309

Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
           E+   +E+ IQA+D GA       K+L+ V DVNDN PE+ +TS++SPV E++  GTVIA
Sbjct: 310 EECSFYEMEIQAEDVGALL--GRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367

Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
            LSV D D+G+NG V C     LPF L  S+ NY+ L T   LDRE V  YN+++ A D 
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427

Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
           GTP LS  T + + V+DINDNPP    +SY  YI ENNL GA I +L+  DPD+ +NA++
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487

Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
           ++ + E   +   +  Y +IN D G++ +L   DYE  R+ +L    SD G P L++N+S
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547

Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
           +++FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY 
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
           LL +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + 
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667

Query: 670 SPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
            PE   E  S   +      +LT YL++++  +S  F+  V  ++  ++ +W +SR L  
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQ- 726

Query: 729 APVSSLYRTPG-PSLHADAVRGGLMSPHLYHQ-VYLTTDSRRSDPLLKKPGAASPLASRQ 786
               S  R  G P+ H   V         Y Q V LT DSR+S  +  +P  A  L S++
Sbjct: 727 ---DSGGRLVGVPASHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLISQE 783

Query: 787 ------NTLRSCDPVFYRQVL--GAESAPPGQVRFSKS 816
                 + L S D   Y+     G ++ P    RFS++
Sbjct: 784 GCEKNDSLLTSVDFHEYKNEADHGQQAPPNTDWRFSQA 821


>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  602 bits (1553), Expect = e-172
 Identities = 337/780 (43%), Positives = 479/780 (61%), Gaps = 14/780 (1%)

Query: 14  GRVVGVLLLLGALNKAST-VIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
           G ++ +  LLG L +     I Y +PEE +KG  VGN+  +LGLD   L+    R+VS  
Sbjct: 11  GELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRG 70

Query: 73  SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
             + F +N  +G +    R+DREELC   P C + +  +VE+  +LF VE+ I DINDNN
Sbjct: 71  RTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130

Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
           P F  ++++++I+E   PG R+PL  A DPDVG NSLQ+Y+LS N +F+L VQT ++   
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190

Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
             ELVLERALDRE E +  LVLTA DGG P  S+++ IH+ VLD NDNAPVF   +YR +
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250

Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
           VLE+ P GTR++ V A+D DEG NG++ Y F   N      LF L+  TG ++I   LD+
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRKINEKQT-PLFQLNENTGEISIAKSLDY 309

Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
           E+   +E+ IQA+D GA       K+L+ V DVNDN PE+ +TS++SPV E++  GTVIA
Sbjct: 310 EECSFYEMEIQAEDVGALL--GRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367

Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
            LSV D D+G+NG V C     LPF L  S+ NY+ L T   LDRE V  YN+++ A D 
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427

Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
           GTP LS  T + + V+DINDNPP    +SY  YI ENNL GA I +L+  DPD+ +NA++
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487

Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
           ++ + E   +   +  Y +IN D G++ +L   DYE  R+ +L    SD G P L++N+S
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547

Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
           +++FV D+NDNAP++LY   P  G + VE+ PR    G+LV++VV  D D+G NAWLSY 
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
           LL +    LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + 
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667

Query: 670 SPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
            PE   E  S   +      +LT YL++++  +S  F+  V  ++  ++ +W +SR L  
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQ- 726

Query: 729 APVSSLYRTPG-PSLHADAVRGGLMSPHLYHQ-VYLTTDSRRSDPLLKKPGAASPLASRQ 786
               S  R  G P+ H   V         Y Q V LT DSR+S  +  +P  A  L S++
Sbjct: 727 ---DSGGRLVGVPASHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLISQE 783


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 1007

 Score =  602 bits (1552), Expect = e-172
 Identities = 311/706 (44%), Positives = 456/706 (64%), Gaps = 5/706 (0%)

Query: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76
           +LLLL     A++ + Y +PEE+  G  VGNV   LGL+L  L     R+  +   S R+
Sbjct: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89

Query: 77  FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136
            E++  +G +FVN+R+DRE LC   P C ++LE++  NP+ + +VEV I DINDN+P FP
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196
               +L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++  ++++K  EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209

Query: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256
           VL + LDRE+     LVLTA+DGG PA S +  I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269

Query: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316
           +P GT VV++ A+D DEG NGE+ YS  S+     RQLF++D  TG + + G LD+E+  
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329

Query: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376
            ++IY+QA D+G  P   HCKVLV++VDVNDNAPE+ +T +YSPVPE+A   T++A+LSV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389

Query: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436
            D D+G N  V+  +   LPF L +   N +TL  S  LDRE V  YN+++TA D G P 
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448

Query: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496
           L++L  ++V++SDINDNPP   + SY +YI+ENNLPG  +  +   DPD  +NA +++ L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508

Query: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556
           LE+  +   V  Y +IN  +G + ++   DYE  REF +T    D G+P L++ ++ N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568

Query: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
           V D ND+AP +LYP    SS   EM+PR   AG+LV++V+  D+D+G NAWL Y L  + 
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628

Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
           +  LF + LHTG+I T R + D       LTV+++DNGEPSLS +  +TV+V +   +  
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688

Query: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
            +             +T YL+++L  VS  F++T+  + I K Y++
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734


>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
           [Homo sapiens]
          Length = 884

 Score =  602 bits (1552), Expect = e-172
 Identities = 311/706 (44%), Positives = 456/706 (64%), Gaps = 5/706 (0%)

Query: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76
           +LLLL     A++ + Y +PEE+  G  VGNV   LGL+L  L     R+  +   S R+
Sbjct: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89

Query: 77  FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136
            E++  +G +FVN+R+DRE LC   P C ++LE++  NP+ + +VEV I DINDN+P FP
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196
               +L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++  ++++K  EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209

Query: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256
           VL + LDRE+     LVLTA+DGG PA S +  I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269

Query: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316
           +P GT VV++ A+D DEG NGE+ YS  S+     RQLF++D  TG + + G LD+E+  
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329

Query: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376
            ++IY+QA D+G  P   HCKVLV++VDVNDNAPE+ +T +YSPVPE+A   T++A+LSV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389

Query: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436
            D D+G N  V+  +   LPF L +   N +TL  S  LDRE V  YN+++TA D G P 
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448

Query: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496
           L++L  ++V++SDINDNPP   + SY +YI+ENNLPG  +  +   DPD  +NA +++ L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508

Query: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556
           LE+  +   V  Y +IN  +G + ++   DYE  REF +T    D G+P L++ ++ N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568

Query: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
           V D ND+AP +LYP    SS   EM+PR   AG+LV++V+  D+D+G NAWL Y L  + 
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628

Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
           +  LF + LHTG+I T R + D       LTV+++DNGEPSLS +  +TV+V +   +  
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688

Query: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
            +             +T YL+++L  VS  F++T+  + I K Y++
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score =  601 bits (1550), Expect = e-172
 Identities = 313/703 (44%), Positives = 455/703 (64%), Gaps = 8/703 (1%)

Query: 15  RVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASR 74
           R++ + LLL      S  +HY IPEE + G  VG +  +LGL+L  L  R FRV S    
Sbjct: 12  RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRG 71

Query: 75  RFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPA 134
              EVN + G +FVN R+DREELC     C++ LE++V+ PL++F VEV ++DINDN P 
Sbjct: 72  DLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPR 131

Query: 135 FPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYA 194
           F  QE +L I E+  P +RFPLE A D D+G+N+   Y L+ NEYF L V+T E+ T + 
Sbjct: 132 FSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFL 191

Query: 195 ELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVL 254
           ELVL ++LDRE     +L++ A DGG P L+ ++ + I VLDANDNAP F++S+Y  R+L
Sbjct: 192 ELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLL 251

Query: 255 EDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFED 314
           E+APSGT V+++ A+D DEG N EI+Y F +     V+  F ++  TG + + G LD+ED
Sbjct: 252 ENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYED 311

Query: 315 TKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALL 374
              +EI I A DK   P   HCKV+V+++DVNDN PE+ +T+++ PV EDAPL TVIAL+
Sbjct: 312 YNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALI 371

Query: 375 SVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGT 434
           SV+D D+G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+
Sbjct: 372 SVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGS 431

Query: 435 PSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSF 494
           PSL A   V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D DA +NA +S+
Sbjct: 432 PSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSY 491

Query: 495 FLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVN 554
            L+E+      +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ 
Sbjct: 492 SLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQ 551

Query: 555 IFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL 611
           +FV D NDNAP +L PR GG+     E++PR   AGH+V++V   D D+G+NAWLSY L 
Sbjct: 552 VFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQ 611

Query: 612 GSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE- 668
            +P  +   F +GL+TG+IST R + +T++PR  L VL+KD+GEP L+ TAT+ VS+ E 
Sbjct: 612 PAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES 671

Query: 669 -DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
             +P+A +   +G+  P     ++  YL++++  VS   V+T+
Sbjct: 672 GQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTL 714


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score =  601 bits (1550), Expect = e-172
 Identities = 313/703 (44%), Positives = 455/703 (64%), Gaps = 8/703 (1%)

Query: 15  RVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASR 74
           R++ + LLL      S  +HY IPEE + G  VG +  +LGL+L  L  R FRV S    
Sbjct: 12  RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRG 71

Query: 75  RFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPA 134
              EVN + G +FVN R+DREELC     C++ LE++V+ PL++F VEV ++DINDN P 
Sbjct: 72  DLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPR 131

Query: 135 FPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYA 194
           F  QE +L I E+  P +RFPLE A D D+G+N+   Y L+ NEYF L V+T E+ T + 
Sbjct: 132 FSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFL 191

Query: 195 ELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVL 254
           ELVL ++LDRE     +L++ A DGG P L+ ++ + I VLDANDNAP F++S+Y  R+L
Sbjct: 192 ELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLL 251

Query: 255 EDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFED 314
           E+APSGT V+++ A+D DEG N EI+Y F +     V+  F ++  TG + + G LD+ED
Sbjct: 252 ENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYED 311

Query: 315 TKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALL 374
              +EI I A DK   P   HCKV+V+++DVNDN PE+ +T+++ PV EDAPL TVIAL+
Sbjct: 312 YNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALI 371

Query: 375 SVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGT 434
           SV+D D+G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+
Sbjct: 372 SVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGS 431

Query: 435 PSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSF 494
           PSL A   V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D DA +NA +S+
Sbjct: 432 PSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSY 491

Query: 495 FLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVN 554
            L+E+      +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ 
Sbjct: 492 SLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQ 551

Query: 555 IFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL 611
           +FV D NDNAP +L PR GG+     E++PR   AGH+V++V   D D+G+NAWLSY L 
Sbjct: 552 VFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQ 611

Query: 612 GSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE- 668
            +P  +   F +GL+TG+IST R + +T++PR  L VL+KD+GEP L+ TAT+ VS+ E 
Sbjct: 612 PAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES 671

Query: 669 -DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
             +P+A +   +G+  P     ++  YL++++  VS   V+T+
Sbjct: 672 GQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTL 714


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,398,928
Number of Sequences: 37866
Number of extensions: 1555611
Number of successful extensions: 10538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3511
Number of HSP's gapped (non-prelim): 707
length of query: 863
length of database: 18,247,518
effective HSP length: 111
effective length of query: 752
effective length of database: 14,044,392
effective search space: 10561382784
effective search space used: 10561382784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press