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Search of human proteins with 14277677
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14277677 protocadherin gamma subfamily C, 3 isoform 2
precursor [Homo sapiens]
(863 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 1701 0.0
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs... 1594 0.0
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 629 e-180
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 629 e-180
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 624 e-178
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 623 e-178
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 619 e-177
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 619 e-177
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs... 619 e-177
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 618 e-177
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 618 e-177
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 618 e-177
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs... 618 e-177
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 616 e-176
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 614 e-176
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 614 e-176
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 610 e-174
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 610 e-174
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 610 e-174
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 607 e-173
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 607 e-173
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 605 e-173
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 603 e-172
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 603 e-172
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 603 e-172
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso... 602 e-172
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 602 e-172
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 602 e-172
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 601 e-172
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 601 e-172
>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
[Homo sapiens]
Length = 863
Score = 1701 bits (4404), Expect = 0.0
Identities = 863/863 (100%), Positives = 863/863 (100%)
Query: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
Sbjct: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
Query: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
Sbjct: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
Sbjct: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
Sbjct: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
Sbjct: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
Sbjct: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
Sbjct: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
Sbjct: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
Sbjct: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
Sbjct: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
Query: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
Sbjct: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
Query: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
Sbjct: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFYSYIILRKEWSCFFSD 840
PLASRQNTLRSCDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFYSYIILRKEWSCFFSD
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFYSYIILRKEWSCFFSD 840
Query: 841 EDVFLVMHSHFQLALPRSKLVPL 863
EDVFLVMHSHFQLALPRSKLVPL
Sbjct: 841 EDVFLVMHSHFQLALPRSKLVPL 863
>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
[Homo sapiens]
Length = 934
Score = 1594 bits (4128), Expect = 0.0
Identities = 810/810 (100%), Positives = 810/810 (100%)
Query: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
Sbjct: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
Query: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
Sbjct: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
Sbjct: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
Sbjct: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
Sbjct: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
Sbjct: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
Sbjct: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
Sbjct: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
Sbjct: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
Sbjct: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
Query: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
Sbjct: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
Query: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
Sbjct: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQ 810
PLASRQNTLRSCDPVFYRQVLGAESAPPGQ
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQ 810
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 629 bits (1622), Expect = e-180
Identities = 360/816 (44%), Positives = 504/816 (61%), Gaps = 21/816 (2%)
Query: 15 RVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
R++ + LLLG L + + I Y + EE+E+G VGN+ +LGL L+ R R+VS
Sbjct: 12 RLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGR 71
Query: 74 RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
+ F +N +G + R+DREELC P+C LE+++E+ +++ VEV I D+NDN P
Sbjct: 72 TQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPP 131
Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
+F T++ +++++E PG RFPL A DPDVG NSLQ Y+L+ N YF+L VQ+ D KY
Sbjct: 132 SFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKY 191
Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
ELVLERALDRE E LVLTA DGG P S + I I ++D NDNAPVF Q Y V
Sbjct: 192 PELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSV 251
Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
E+ P GTR++ V ATD DEG NG++ YSF R + QLF L+ ++G +TI G LD+E
Sbjct: 252 RENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYE 310
Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
D+ ++I ++A D A KVLV V+D NDNAPE+TVTS+ S V E + GTVIAL
Sbjct: 311 DSGFYDIDVEAHD--GPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIAL 368
Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
+V D D+G NGLVTC +P LPF+L + NY+ L T LDRE V EYN+++TA D G
Sbjct: 369 FNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQG 428
Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
TP LS T + +QV DINDNPP +SY YI ENN GA IL+++ DPD+ NAR++
Sbjct: 429 TPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARIT 488
Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
+ L E + + Y +IN + GI+ +L DYE R+ +L SD G P L++N+S+
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSL 548
Query: 554 NIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
++FV D+NDN P++LY P G + VE+ PR +G+LV++VV D D+G NAWLSYSL
Sbjct: 549 SLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSL 608
Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
L S LFA+GLHTG++ TAR + D D+ +Q L V+++D+G+P LS T TLTV+V +
Sbjct: 609 LKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSI 668
Query: 671 PEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRA 729
P+ A+ S + LT YL++++ VS F+ V ++ K+ +W +SR L A
Sbjct: 669 PDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSR-LLHA 727
Query: 730 PVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNT 788
S L P + D VR L + H+V LT DSR+S + +P A L SR++
Sbjct: 728 EGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFSQPSYADTLISRESC 785
Query: 789 LRSCDPVFYRQVL-------GAESAPPG-QVRFSKS 816
+S +P+ Q L + APP RFS++
Sbjct: 786 EKS-EPLLITQDLLETKGDPNLQQAPPNTDWRFSQA 820
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 629 bits (1621), Expect = e-180
Identities = 355/803 (44%), Positives = 498/803 (62%), Gaps = 12/803 (1%)
Query: 15 RVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
R++ + LLLG L + + I Y + EE+E+G VGN+ +LGL L+ R R+VS
Sbjct: 12 RLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGR 71
Query: 74 RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
+ F +N +G + R+DREELC P+C LE+++E+ +++ VEV I D+NDN P
Sbjct: 72 TQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPP 131
Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
+F T++ +++++E PG RFPL A DPDVG NSLQ Y+L+ N YF+L VQ+ D KY
Sbjct: 132 SFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKY 191
Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
ELVLERALDRE E LVLTA DGG P S + I I ++D NDNAPVF Q Y V
Sbjct: 192 PELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSV 251
Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
E+ P GTR++ V ATD DEG NG++ YSF R + QLF L+ ++G +TI G LD+E
Sbjct: 252 RENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYE 310
Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
D+ ++I ++A D A KVLV V+D NDNAPE+TVTS+ S V E + GTVIAL
Sbjct: 311 DSGFYDIDVEAHD--GPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIAL 368
Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
+V D D+G NGLVTC +P LPF+L + NY+ L T LDRE V EYN+++TA D G
Sbjct: 369 FNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQG 428
Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
TP LS T + +QV DINDNPP +SY YI ENN GA IL+++ DPD+ NAR++
Sbjct: 429 TPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARIT 488
Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
+ L E + + Y +IN + GI+ +L DYE R+ +L SD G P L++N+S+
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSL 548
Query: 554 NIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
++FV D+NDN P++LY P G + VE+ PR +G+LV++VV D D+G NAWLSYSL
Sbjct: 549 SLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSL 608
Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
L S LFA+GLHTG++ TAR + D D+ +Q L V+++D+G+P LS T TLTV+V +
Sbjct: 609 LKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSI 668
Query: 671 PEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRA 729
P+ A+ S + LT YL++++ VS F+ V ++ K+ +W +SR L A
Sbjct: 669 PDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSR-LLHA 727
Query: 730 PVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNT 788
S L P + D VR L + H+V LT DSR+S + +P A L SR++
Sbjct: 728 EGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFSQPSYADTLISRESC 785
Query: 789 LRSCDPVFYRQVLGAESAPPGQV 811
+S + + +L + P QV
Sbjct: 786 EKSEPLLITQDLLETKGDPNLQV 808
>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 624 bits (1609), Expect = e-178
Identities = 347/802 (43%), Positives = 494/802 (61%), Gaps = 13/802 (1%)
Query: 19 VLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFF 77
+L LLG L A+ I Y IPEE EKG VGN+V +LGL+ L+ R+VS + F
Sbjct: 16 LLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLF 75
Query: 78 EVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPT 137
+N G + R+DREELC P C V+ ++VE+ L L+ VEV I DINDN P F
Sbjct: 76 SLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLK 135
Query: 138 QEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELV 197
+E++++I E AP +RFPL +DPDVG NSLQ ++LS N +F++ VQ+ KY ELV
Sbjct: 136 EELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELV 195
Query: 198 LERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDA 257
LE LDRE E +LVLTA+DGG P S+ I + VLD NDN P+F Q +YR V E+
Sbjct: 196 LEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENL 255
Query: 258 PSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKL 317
P GT V+ V ATD DEG +GE+ YSF + Q+F L+++TG ++ LD+ED+
Sbjct: 256 PVGTPVLAVTATDQDEGVHGEVTYSFVKITEK-ISQIFCLNVLTGEISTSANLDYEDSSF 314
Query: 318 HEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVT 377
+E+ ++A+D + A KVL+ ++DVNDN PE+ VTS + E AP GTVIAL V
Sbjct: 315 YELGVEARDGPGLRDRA--KVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVF 372
Query: 378 DLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSL 437
D D+G NGLVTC +P LPF L S+ NY+ L T+A LDRE V YN+++TA D GTP L
Sbjct: 373 DRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPL 432
Query: 438 SALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLL 497
S TI+ + V+D NDNPP SSY VY+ ENN GA I +++ DPD QNA++S+ L
Sbjct: 433 STETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLA 492
Query: 498 EQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFV 557
E + + Y +IN D GI+ +L DYE R+ +L SD G P L++N+S+++FV
Sbjct: 493 EDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFV 552
Query: 558 TDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY LL +
Sbjct: 553 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 612
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+
Sbjct: 613 EPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDIL 672
Query: 675 AEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSS 733
A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L +A
Sbjct: 673 ADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSR-LLQASGGG 731
Query: 734 LYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSC 792
L PG + + VR L + H+V LT DSR+S + +P A L ++++ +S
Sbjct: 732 LASMPGSHFVGVEGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKS- 788
Query: 793 DPVFYRQVLGAESAPPGQVRFS 814
+P+ Q L P Q++ S
Sbjct: 789 EPLLITQDLLETKGEPRQLQVS 810
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 623 bits (1606), Expect = e-178
Identities = 346/800 (43%), Positives = 493/800 (61%), Gaps = 13/800 (1%)
Query: 19 VLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFF 77
+L LLG L A+ I Y IPEE EKG VGN+V +LGL+ L+ R+VS + F
Sbjct: 16 LLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLF 75
Query: 78 EVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPT 137
+N G + R+DREELC P C V+ ++VE+ L L+ VEV I DINDN P F
Sbjct: 76 SLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLK 135
Query: 138 QEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELV 197
+E++++I E AP +RFPL +DPDVG NSLQ ++LS N +F++ VQ+ KY ELV
Sbjct: 136 EELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELV 195
Query: 198 LERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDA 257
LE LDRE E +LVLTA+DGG P S+ I + VLD NDN P+F Q +YR V E+
Sbjct: 196 LEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENL 255
Query: 258 PSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKL 317
P GT V+ V ATD DEG +GE+ YSF + Q+F L+++TG ++ LD+ED+
Sbjct: 256 PVGTPVLAVTATDQDEGVHGEVTYSFVKITEK-ISQIFCLNVLTGEISTSANLDYEDSSF 314
Query: 318 HEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVT 377
+E+ ++A+D + A KVL+ ++DVNDN PE+ VTS + E AP GTVIAL V
Sbjct: 315 YELGVEARDGPGLRDRA--KVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVF 372
Query: 378 DLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSL 437
D D+G NGLVTC +P LPF L S+ NY+ L T+A LDRE V YN+++TA D GTP L
Sbjct: 373 DRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPL 432
Query: 438 SALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLL 497
S TI+ + V+D NDNPP SSY VY+ ENN GA I +++ DPD QNA++S+ L
Sbjct: 433 STETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLA 492
Query: 498 EQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFV 557
E + + Y +IN D GI+ +L DYE R+ +L SD G P L++N+S+++FV
Sbjct: 493 EDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFV 552
Query: 558 TDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY LL +
Sbjct: 553 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 612
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+
Sbjct: 613 EPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDIL 672
Query: 675 AEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSS 733
A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L +A
Sbjct: 673 ADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSR-LLQASGGG 731
Query: 734 LYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSC 792
L PG + + VR L + H+V LT DSR+S + +P A L ++++ +S
Sbjct: 732 LASMPGSHFVGVEGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKS- 788
Query: 793 DPVFYRQVLGAESAPPGQVR 812
+P+ Q L P Q++
Sbjct: 789 EPLLITQDLLETKGEPRQLQ 808
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 619 bits (1595), Expect = e-177
Identities = 344/790 (43%), Positives = 497/790 (62%), Gaps = 16/790 (2%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y +PEE EKG VGN+ +LGL+ L+ R R+VS + F VN +G + R+
Sbjct: 32 IRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRI 91
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREELC T+ SC + +EL+VE+ L+++ VEV I DINDN P+F E+++++SE PG
Sbjct: 92 DREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGA 151
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RF L +A DPDVG NSLQ+Y+LS N YF+L+++ R D K ELVLE +LDRE+E + L
Sbjct: 152 RFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLL 211
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
+LTALDGG P ++PI + VLD ND+ P+F QS+YR V E+ SGTRV+ V ATD D
Sbjct: 212 LLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPD 271
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE++YSF + + ++F LD TG + ++G LDFE + +E+ IQ +D G
Sbjct: 272 EGINGEVMYSF-RNMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGG--L 328
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
+L+ VVDVNDNAPEIT+TS + + E++P GTVIALL+V D D+GENG V+C +P
Sbjct: 329 FTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIP 388
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L + NY+ L TS LDRE V YN+++TA D G+P LSA T V + V+D ND
Sbjct: 389 NHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDND 448
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SSY YI ENN GA I +++ DPD+ QNA +++ L + + + Y +I
Sbjct: 449 NPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI 508
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
N + G++ +L DYE R+ EL D G P L++N+S+++FV D+NDNAP++LY
Sbjct: 509 NSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 568
Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
P G + VE+ PR G+LV++VV D D+G NAWLSY LL + LFA+G HTG++
Sbjct: 569 PTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 628
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPS-GSAPREQKK 688
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + PE A+ S S +
Sbjct: 629 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETS 688
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTP-GPSLHADAV 747
+L+ YL++++ VS F+V V ++ ++++W +SR L +A L P + D V
Sbjct: 689 DLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSR-LLQASEGGLAGMPTSHFVGVDGV 747
Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQ----VLGA 803
+ L + H+V L DS++S + +P L S+++ +S +P+ + +LG
Sbjct: 748 QAFLQT--YSHEVSLIADSQKSHLIFPQPNYGDTLISQESCEKS-EPLLIAEDSAIILGK 804
Query: 804 ESAPPGQVRF 813
QVRF
Sbjct: 805 CDPTSNQVRF 814
>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 619 bits (1595), Expect = e-177
Identities = 334/781 (42%), Positives = 490/781 (62%), Gaps = 14/781 (1%)
Query: 14 GRVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
GR+V + LLG L +A ++ I Y +PEE EKG+ VGN+ +L L+ L+ RR R+VS
Sbjct: 11 GRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRG 70
Query: 73 SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
+ F +N +G + R+DREELC P C V +++VE+ ++L+ +E+ + DIND+
Sbjct: 71 RTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130
Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
P F + ++++I+E PG R+PL A DPDVG NSLQ+Y+LS N +F+L VQT ++
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190
Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
ELVLERALDRE + LVLTA DGG P S+++ IH+ VLD NDNAPVF Q +YR +
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250
Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
VLE+ P GT ++ A+DLDEG NG++ Y F N LF L+ TG ++ LD+
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEK-QSLLFQLNENTGEISTAKSLDY 309
Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
E+ +E+ IQA+D G KVL+ V DVNDN PE+T+TS++SPV EDAP GTVI
Sbjct: 310 EECSFYEMEIQAEDGGGLK--GWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367
Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
L + D D+G+NG V C + L F+L +S ++Y+ L T+ LDRE EYN+++TA D
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427
Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
GTP LS + +QV+DINDNPP SQ+SY VY+ ENN G I ++ +DPD+ +N+R+
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487
Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
+ L E + + Y +IN D G++ +L DYE R+ ++ SD G+P L++N+S
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547
Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
+ +FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
L + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV++ +
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667
Query: 670 SPEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
P+ A+ S P + + +LT YL++++ +VS F+ V ++ ++ W S L R
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWHSSH-LLR 726
Query: 729 APVSSLYRTP-GPSLHADAVRGGLMSPHLYHQVY-LTTDSRRSDPLLKKPGAASPLASRQ 786
A L P + D VR L + Y Q + LT DSR+S + +P A L S+Q
Sbjct: 727 ATSDGLAGVPTSHFVGVDGVRAFLQT---YSQEFSLTADSRKSHLIFPQPNYADTLISQQ 783
Query: 787 N 787
+
Sbjct: 784 S 784
>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
[Homo sapiens]
Length = 828
Score = 619 bits (1595), Expect = e-177
Identities = 334/781 (42%), Positives = 490/781 (62%), Gaps = 14/781 (1%)
Query: 14 GRVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
GR+V + LLG L +A ++ I Y +PEE EKG+ VGN+ +L L+ L+ RR R+VS
Sbjct: 11 GRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRG 70
Query: 73 SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
+ F +N +G + R+DREELC P C V +++VE+ ++L+ +E+ + DIND+
Sbjct: 71 RTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130
Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
P F + ++++I+E PG R+PL A DPDVG NSLQ+Y+LS N +F+L VQT ++
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190
Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
ELVLERALDRE + LVLTA DGG P S+++ IH+ VLD NDNAPVF Q +YR +
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250
Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
VLE+ P GT ++ A+DLDEG NG++ Y F N LF L+ TG ++ LD+
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEK-QSLLFQLNENTGEISTAKSLDY 309
Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
E+ +E+ IQA+D G KVL+ V DVNDN PE+T+TS++SPV EDAP GTVI
Sbjct: 310 EECSFYEMEIQAEDGGGLK--GWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367
Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
L + D D+G+NG V C + L F+L +S ++Y+ L T+ LDRE EYN+++TA D
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427
Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
GTP LS + +QV+DINDNPP SQ+SY VY+ ENN G I ++ +DPD+ +N+R+
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487
Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
+ L E + + Y +IN D G++ +L DYE R+ ++ SD G+P L++N+S
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547
Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
+ +FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
L + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV++ +
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667
Query: 670 SPEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
P+ A+ S P + + +LT YL++++ +VS F+ V ++ ++ W S L R
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWHSSH-LLR 726
Query: 729 APVSSLYRTP-GPSLHADAVRGGLMSPHLYHQVY-LTTDSRRSDPLLKKPGAASPLASRQ 786
A L P + D VR L + Y Q + LT DSR+S + +P A L S+Q
Sbjct: 727 ATSDGLAGVPTSHFVGVDGVRAFLQT---YSQEFSLTADSRKSHLIFPQPNYADTLISQQ 783
Query: 787 N 787
+
Sbjct: 784 S 784
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 618 bits (1594), Expect = e-177
Identities = 340/768 (44%), Positives = 483/768 (62%), Gaps = 12/768 (1%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y IPEE EKG VGN+ +LGL L+ R R+VS + F +N +G + R+
Sbjct: 35 ISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRI 94
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREELC C V+ ++VE+ ++LF +E+ + DINDN P F + + ++I+E VA G
Sbjct: 95 DREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGM 154
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RFPL A DPDVG NSLQ+Y+LS N++F+LRVQ+R + KY ELVLE +LDRE E L
Sbjct: 155 RFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHL 214
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTA DGG P S ++ + + V DANDNAPVF YR V E+ P GT+++ V ATD D
Sbjct: 215 VLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRD 274
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE+ YSF + + F L+ TG + I LD+E+T +EI IQA+D GA
Sbjct: 275 EGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYL- 332
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
A KVL+ V DVNDN+PE+T+TS++SPV ED+PLGTV+ALL+V DLD+ +NG VTC +
Sbjct: 333 -ATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL 391
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L S+ +Y+ L LDRE V YN+++TA D G+P LS +QV+DIND
Sbjct: 392 AYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADIND 451
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SQ SY YI ENN GA I +++ DPD+ +NA++ + L E + + Y +I
Sbjct: 452 NPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISI 511
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
N D G++ +L DYE E ++ SD G P L++N+S+++FV D+NDNAP++LY
Sbjct: 512 NSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 571
Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
P G + VE+ PR G+LV++VV D D+G NAWLSY LL + LFA+G HTG++
Sbjct: 572 PTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 631
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAP-REQKK 688
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+ A+ S +P +
Sbjct: 632 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETS 691
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADAV 747
+LT YL++++ VS F+ V ++ ++ +W +SR L +A L G + D V
Sbjct: 692 DLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSR-LLQASGGGLTGVSGSHFVGVDGV 750
Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPV 795
R L + H+V LT DSR+S + +P A L S+++ ++ DP+
Sbjct: 751 RAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKN-DPL 795
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 618 bits (1594), Expect = e-177
Identities = 340/768 (44%), Positives = 483/768 (62%), Gaps = 12/768 (1%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y IPEE EKG VGN+ +LGL L+ R R+VS + F +N +G + R+
Sbjct: 35 ISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRI 94
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREELC C V+ ++VE+ ++LF +E+ + DINDN P F + + ++I+E VA G
Sbjct: 95 DREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGM 154
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RFPL A DPDVG NSLQ+Y+LS N++F+LRVQ+R + KY ELVLE +LDRE E L
Sbjct: 155 RFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHL 214
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTA DGG P S ++ + + V DANDNAPVF YR V E+ P GT+++ V ATD D
Sbjct: 215 VLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRD 274
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE+ YSF + + F L+ TG + I LD+E+T +EI IQA+D GA
Sbjct: 275 EGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYL- 332
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
A KVL+ V DVNDN+PE+T+TS++SPV ED+PLGTV+ALL+V DLD+ +NG VTC +
Sbjct: 333 -ATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL 391
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L S+ +Y+ L LDRE V YN+++TA D G+P LS +QV+DIND
Sbjct: 392 AYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADIND 451
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SQ SY YI ENN GA I +++ DPD+ +NA++ + L E + + Y +I
Sbjct: 452 NPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISI 511
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
N D G++ +L DYE E ++ SD G P L++N+S+++FV D+NDNAP++LY
Sbjct: 512 NSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 571
Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
P G + VE+ PR G+LV++VV D D+G NAWLSY LL + LFA+G HTG++
Sbjct: 572 PTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 631
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAP-REQKK 688
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+ A+ S +P +
Sbjct: 632 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETS 691
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADAV 747
+LT YL++++ VS F+ V ++ ++ +W +SR L +A L G + D V
Sbjct: 692 DLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSR-LLQASGGGLTGVSGSHFVGVDGV 750
Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPV 795
R L + H+V LT DSR+S + +P A L S+++ ++ DP+
Sbjct: 751 RAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKN-DPL 795
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 618 bits (1594), Expect = e-177
Identities = 345/795 (43%), Positives = 497/795 (62%), Gaps = 14/795 (1%)
Query: 14 GRVVGVLL-LLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSG 71
GR + +L LLG L S I Y + EE +KG VGN+ +LGL+ L+ R R+VS
Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69
Query: 72 ASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDN 131
+ F +N ++G + +R+DREELC +P C V + ++VE+ L++F VE+ I+DINDN
Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129
Query: 132 NPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDST 191
P FPT+E++++I E PGTRFP+++A DPDVG NSLQ Y+LS N+YF+L V + +
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189
Query: 192 KYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRA 251
KY ELVLERALDRE++ QLVL A DGG P S +L I + VLDANDN P+F Q YR
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249
Query: 252 RVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLD 311
V E+ P GTR++ V ATD DEG N ++ Y + ++F L+ V+G ++I LD
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308
Query: 312 FEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVI 371
+ED +EI I+A+D A K+LV V+DVNDNAPEIT+TS+ S VPE+ +G I
Sbjct: 309 YEDAMFYEIKIEAQDGPGLLSRA--KILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366
Query: 372 ALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARD 431
AL+ V D D+G+NG V V LPF L S+ Y+ L T+ LDRE + EYN+S+ A D
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426
Query: 432 AGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNAR 491
G+P LS T + + V DINDNPP SY YI ENN GA I +++ DPD+ NAR
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486
Query: 492 LSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNI 551
+++ L E + + + +IN + G++ +L DYE R+ +L SD G P L++N+
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Query: 552 SVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSY 608
S+N+FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 609 SLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE 668
LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 669 DSPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLY 727
P+ A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L
Sbjct: 667 RIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSR-LL 725
Query: 728 RAPVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQ 786
+A L TPG + AD VR L + H+V LT DSR+S + +P A L S++
Sbjct: 726 QASGGGLASTPGSHFVGADGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQE 783
Query: 787 NTLRSCDPVFYRQVL 801
+ +S +P+ Q L
Sbjct: 784 SCEKS-EPLLITQDL 797
>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
[Homo sapiens]
Length = 829
Score = 618 bits (1594), Expect = e-177
Identities = 345/795 (43%), Positives = 497/795 (62%), Gaps = 14/795 (1%)
Query: 14 GRVVGVLL-LLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSG 71
GR + +L LLG L S I Y + EE +KG VGN+ +LGL+ L+ R R+VS
Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69
Query: 72 ASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDN 131
+ F +N ++G + +R+DREELC +P C V + ++VE+ L++F VE+ I+DINDN
Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129
Query: 132 NPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDST 191
P FPT+E++++I E PGTRFP+++A DPDVG NSLQ Y+LS N+YF+L V + +
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189
Query: 192 KYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRA 251
KY ELVLERALDRE++ QLVL A DGG P S +L I + VLDANDN P+F Q YR
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249
Query: 252 RVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLD 311
V E+ P GTR++ V ATD DEG N ++ Y + ++F L+ V+G ++I LD
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLD 308
Query: 312 FEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVI 371
+ED +EI I+A+D A K+LV V+DVNDNAPEIT+TS+ S VPE+ +G I
Sbjct: 309 YEDAMFYEIKIEAQDGPGLLSRA--KILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366
Query: 372 ALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARD 431
AL+ V D D+G+NG V V LPF L S+ Y+ L T+ LDRE + EYN+S+ A D
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426
Query: 432 AGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNAR 491
G+P LS T + + V DINDNPP SY YI ENN GA I +++ DPD+ NAR
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486
Query: 492 LSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNI 551
+++ L E + + + +IN + G++ +L DYE R+ +L SD G P L++N+
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Query: 552 SVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSY 608
S+N+FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 609 SLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE 668
LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 669 DSPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLY 727
P+ A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L
Sbjct: 667 RIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSR-LL 725
Query: 728 RAPVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQ 786
+A L TPG + AD VR L + H+V LT DSR+S + +P A L S++
Sbjct: 726 QASGGGLASTPGSHFVGADGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQE 783
Query: 787 NTLRSCDPVFYRQVL 801
+ +S +P+ Q L
Sbjct: 784 SCEKS-EPLLITQDL 797
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 616 bits (1588), Expect = e-176
Identities = 347/805 (43%), Positives = 499/805 (61%), Gaps = 33/805 (4%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y +PEE EKG VGN+ +LGL+ L+ R R+VS + F VN +G + R+
Sbjct: 32 IRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRI 91
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREELC T+ SC + +EL+VE+ L+++ VEV I DINDN P+F E+++++SE PG
Sbjct: 92 DREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGA 151
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RF L +A DPDVG NSLQ+Y+LS N YF+L+++ R D K ELVLE +LDRE+E + L
Sbjct: 152 RFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLL 211
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
+LTALDGG P ++PI + VLD ND+ P+F QS+YR V E+ SGTRV+ V ATD D
Sbjct: 212 LLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPD 271
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE++YSF + + ++F LD TG + ++G LDFE + +E+ IQ +D G
Sbjct: 272 EGINGEVMYSF-RNMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGG--L 328
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
+L+ VVDVNDNAPEIT+TS + + E++P GTVIALL+V D D+GENG V+C +P
Sbjct: 329 FTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIP 388
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L + NY+ L TS LDRE V YN+++TA D G+P LSA T V + V+D ND
Sbjct: 389 NHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDND 448
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SSY YI ENN GA I +++ DPD+ QNA +++ L + + + Y +I
Sbjct: 449 NPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI 508
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY--- 569
N + G++ +L DYE R+ EL D G P L++N+S+++FV D+NDNAP++LY
Sbjct: 509 NSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 568
Query: 570 PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
P G + VE+ PR G+LV++VV D D+G NAWLSY LL + LFA+G HTG++
Sbjct: 569 PTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 628
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPS-GSAPREQKK 688
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + PE A+ S S +
Sbjct: 629 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETS 688
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTP-GPSLHADAV 747
+L+ YL++++ VS F+V V ++ ++++W +SR L +A L P + D V
Sbjct: 689 DLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSR-LLQASEGGLAGMPTSHFVGVDGV 747
Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS---------------C 792
+ L + H+V L DS++S + +P L S+++ +S C
Sbjct: 748 QAFLQT--YSHEVSLIADSQKSHLIFPQPNYGDTLISQESCEKSEPLLIAEDSAIILGKC 805
Query: 793 DPVFYRQVLGAESAPPG-QVRFSKS 816
DP +Q APP RFS++
Sbjct: 806 DPTSNQQ------APPNTDWRFSQA 824
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 614 bits (1584), Expect = e-176
Identities = 319/698 (45%), Positives = 453/698 (64%), Gaps = 8/698 (1%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
LLLL A S +HY + EE + G VG + +LGL+L L R FRV S EV
Sbjct: 18 LLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ LE++V+ PL++F VEV ++DINDN P FP
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAV 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
L ISE+ PG+RF LE A D D+G+NSL TY L EYF L V+ ++ K LVL+
Sbjct: 138 KNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLK 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
+ L+RE P L++TA+DGG P L+ + + I VLD NDNAP F +++Y+ R+LE+AP+
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT VV V ATDLDEG N +I YSF + A + F LD V G +++KG +DFE++K +E
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I ++A DKG P HC VL+E+VD+NDN PE+ + S+ PV ED+PL TVIAL+SV+D
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
V V+V+D+NDN P SQS Y V+++ENN PG I +S D DA +NA +S+ L+E+
Sbjct: 438 TASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
NDNAP +L PR GG+ E++PR AGH+V++V DAD+G+NAWLSY L
Sbjct: 558 ENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGG 617
Query: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
+ F +GL+TG+IST R + + D+PR L VL+KD+GEPSL+ TAT+ VS+ E +P+
Sbjct: 618 ARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
A ++ +G + P ++ YL++++ VS V+T+
Sbjct: 678 ASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTL 715
>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 614 bits (1584), Expect = e-176
Identities = 319/698 (45%), Positives = 453/698 (64%), Gaps = 8/698 (1%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
LLLL A S +HY + EE + G VG + +LGL+L L R FRV S EV
Sbjct: 18 LLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ LE++V+ PL++F VEV ++DINDN P FP
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAV 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
L ISE+ PG+RF LE A D D+G+NSL TY L EYF L V+ ++ K LVL+
Sbjct: 138 KNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLK 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
+ L+RE P L++TA+DGG P L+ + + I VLD NDNAP F +++Y+ R+LE+AP+
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT VV V ATDLDEG N +I YSF + A + F LD V G +++KG +DFE++K +E
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I ++A DKG P HC VL+E+VD+NDN PE+ + S+ PV ED+PL TVIAL+SV+D
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
V V+V+D+NDN P SQS Y V+++ENN PG I +S D DA +NA +S+ L+E+
Sbjct: 438 TASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
NDNAP +L PR GG+ E++PR AGH+V++V DAD+G+NAWLSY L
Sbjct: 558 ENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGG 617
Query: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
+ F +GL+TG+IST R + + D+PR L VL+KD+GEPSL+ TAT+ VS+ E +P+
Sbjct: 618 ARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
A ++ +G + P ++ YL++++ VS V+T+
Sbjct: 678 ASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTL 715
>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
sapiens]
Length = 814
Score = 610 bits (1574), Expect = e-174
Identities = 321/712 (45%), Positives = 457/712 (64%), Gaps = 9/712 (1%)
Query: 6 WRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARR 65
WR G + + R++ +LLLL A S +HY +PEE + G VG + +LGL+L L R
Sbjct: 5 WR-GELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
Query: 66 FRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVI 125
FRV S R EV+ + G +FVN R+DREELCG C++ LE++V+ PL++F V+V +
Sbjct: 64 FRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV 123
Query: 126 QDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQ 185
+D+NDN P F ++ KL +SE+ P +RFPLE A D DVG+NS+ TY LS ++YF L V
Sbjct: 124 KDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVN 183
Query: 186 TREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFN 245
++ D K ELVL ++LDRE P+ L LTA DGG P L+ ++ + + VLD NDNAP F
Sbjct: 184 SKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFE 243
Query: 246 QSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLT 305
QS Y R+ E+A +GT V+++ A+D DEG NG I YSF S V F++D TG +
Sbjct: 244 QSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIV 303
Query: 306 IKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDA 365
I+G LDFE L++I I A DKG P HC VLV ++D NDN PEI +TS+ PV EDA
Sbjct: 304 IRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDA 363
Query: 366 PLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNL 425
GTVIAL+SV DLD+G NG VTC + P +PF L S+ KNY++L + LDRE V Y L
Sbjct: 364 QFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYEL 423
Query: 426 SITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPD 485
+TARD G+PSL A + V+V+D+NDN P +Q Y V+++ENN PG I +S D D
Sbjct: 424 VVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
Query: 486 APQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTP 545
A +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G P
Sbjct: 484 AQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVP 543
Query: 546 VLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGH 602
L +N+++ +FV D NDNAP +L PR GG++ +++PR AGH+V++V DAD+G+
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGY 603
Query: 603 NAWLSYSL--LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
NAWLSY L S + F +GL+TG+IST R + + DSPR L VL+KD+GEP+L+ TA
Sbjct: 604 NAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATA 663
Query: 661 TLTVSVTE--DSPEARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
T+ VS+ E +P+A + +G P ++ YL++++ VS V+T+
Sbjct: 664 TVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTL 715
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 610 bits (1574), Expect = e-174
Identities = 321/712 (45%), Positives = 457/712 (64%), Gaps = 9/712 (1%)
Query: 6 WRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARR 65
WR G + + R++ +LLLL A S +HY +PEE + G VG + +LGL+L L R
Sbjct: 5 WR-GELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
Query: 66 FRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVI 125
FRV S R EV+ + G +FVN R+DREELCG C++ LE++V+ PL++F V+V +
Sbjct: 64 FRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV 123
Query: 126 QDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQ 185
+D+NDN P F ++ KL +SE+ P +RFPLE A D DVG+NS+ TY LS ++YF L V
Sbjct: 124 KDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVN 183
Query: 186 TREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFN 245
++ D K ELVL ++LDRE P+ L LTA DGG P L+ ++ + + VLD NDNAP F
Sbjct: 184 SKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFE 243
Query: 246 QSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLT 305
QS Y R+ E+A +GT V+++ A+D DEG NG I YSF S V F++D TG +
Sbjct: 244 QSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIV 303
Query: 306 IKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDA 365
I+G LDFE L++I I A DKG P HC VLV ++D NDN PEI +TS+ PV EDA
Sbjct: 304 IRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDA 363
Query: 366 PLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNL 425
GTVIAL+SV DLD+G NG VTC + P +PF L S+ KNY++L + LDRE V Y L
Sbjct: 364 QFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYEL 423
Query: 426 SITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPD 485
+TARD G+PSL A + V+V+D+NDN P +Q Y V+++ENN PG I +S D D
Sbjct: 424 VVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
Query: 486 APQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTP 545
A +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G P
Sbjct: 484 AQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVP 543
Query: 546 VLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGH 602
L +N+++ +FV D NDNAP +L PR GG++ +++PR AGH+V++V DAD+G+
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGY 603
Query: 603 NAWLSYSL--LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
NAWLSY L S + F +GL+TG+IST R + + DSPR L VL+KD+GEP+L+ TA
Sbjct: 604 NAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATA 663
Query: 661 TLTVSVTE--DSPEARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709
T+ VS+ E +P+A + +G P ++ YL++++ VS V+T+
Sbjct: 664 TVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTL 715
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 610 bits (1572), Expect = e-174
Identities = 346/821 (42%), Positives = 501/821 (61%), Gaps = 24/821 (2%)
Query: 9 GLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV 68
GLV G ++G L G T I Y +PEE EKG VG++ +LGL+ L+ R R+
Sbjct: 12 GLVLLGILLGTLWETGC-----TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRI 66
Query: 69 VSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDI 128
+ + F +N +G + R+DREELC C + L++++E+ ++++ VEV ++DI
Sbjct: 67 IPRGRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDI 126
Query: 129 NDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTRE 188
NDN P F E++++ISE A RFPL A DPD+G NSLQ+YELS N +F+L VQ
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGA 186
Query: 189 DSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSL 248
D +KY ELVL+RALDRE + + LVLTA DGG P + + I + VLDANDNAP F Q
Sbjct: 187 DGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPE 246
Query: 249 YRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKG 308
YRA V E+ GT+++ V ATD DEG N E+ YSF + Q+F LD +G ++ G
Sbjct: 247 YRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIG 305
Query: 309 RLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLG 368
LD E++ +++ +QA D A KVL+ V+DVNDNAPE+ +TS+ S VPE++P G
Sbjct: 306 ELDHEESGFYQMEVQAMDNAG--YSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRG 363
Query: 369 TVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSIT 428
T+IALL+V D D+ ENG V C + LPF L S NY++L T LDRE VP YN+++T
Sbjct: 364 TLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVT 423
Query: 429 ARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQ 488
A D GTP LS T + + V+D NDNPP Q+SY YI ENN G +++++ DPD +
Sbjct: 424 ATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEE 483
Query: 489 NARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLA 548
NA++++ L E + + Y +IN D G++ +L DYE R+ ++ D G P L+
Sbjct: 484 NAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLS 543
Query: 549 TNISVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAW 605
+N+S+++FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAW
Sbjct: 544 SNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAW 603
Query: 606 LSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVS 665
LSY LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+
Sbjct: 604 LSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 663
Query: 666 VTEDSPEARAEFPSGSAP-REQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSR 724
V + P+ A+ S +P + +LT YL++++ VS F+ V ++ ++ +W +SR
Sbjct: 664 VADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSR 723
Query: 725 DLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-HQVYLTTDSRRSDPLLKKPGAASPLA 783
L +A L T P+ H V G Y H+V LTTDSR+S + +P A L
Sbjct: 724 -LLQASGGGL--TGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLV 780
Query: 784 SRQN------TLRSCDPVFYRQVLG-AESAPPG-QVRFSKS 816
S+++ L S D VF + G E APP RFS++
Sbjct: 781 SQESFEKSEPLLLSGDSVFSKDSHGLIEQAPPNTDWRFSQA 821
>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
sapiens]
Length = 798
Score = 607 bits (1565), Expect = e-173
Identities = 314/713 (44%), Positives = 460/713 (64%), Gaps = 9/713 (1%)
Query: 5 AWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSAR 64
+W SG S R++ +LLLL A + +HY + EE + G VG + +LGL+L L R
Sbjct: 4 SWGSGQESR-RLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR 62
Query: 65 RFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVV 124
FRV S EVN + G +FVN R+DREELC C++ LE++V+ PL++F V+V
Sbjct: 63 LFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVE 122
Query: 125 IQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRV 184
++DINDN P FP + L I+E+ +RFPLE A D D+G N+L TY LS NEYF+L
Sbjct: 123 VRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEK 182
Query: 185 QTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVF 244
++ K L+L ++LDRE P + LVLTA DGG P L+ ++ + I VLDANDNAP F
Sbjct: 183 PPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAF 242
Query: 245 NQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGML 304
++++Y+ R+LE+ P+GT V+++ A+DLDEG NG+I+YSF + V+ F +D +TG +
Sbjct: 243 DRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQI 302
Query: 305 TIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPED 364
+KG +DFE++K +EI ++ DKG P HC+V+VEV D NDN P++ S+ P+ ED
Sbjct: 303 IVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIRED 362
Query: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYN 424
APLGTVIAL+SV+D D G NGLVTC + +PF L S+ KNY++L + LDRE+V Y
Sbjct: 363 APLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYE 422
Query: 425 LSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDP 484
L +TARD G+PSL A V V+V+D+NDN P +Q Y V+++ENN PG I +S WD
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482
Query: 485 DAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGT 544
DA +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGV 542
Query: 545 PVLATNISVNIFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAG 601
P L +N+++ +FV D NDNAP +L PR GG+ E++P GH+V++V DAD+G
Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSG 602
Query: 602 HNAWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTT 659
+NAWLSY L + F +GL+TG+IST R + +TD+PR L VL+KD+GEP+L+ T
Sbjct: 603 YNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTAT 662
Query: 660 ATLTVSVTE--DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
AT+ VS+ E +P+A + G+ P ++ YL++++ VS V+T+
Sbjct: 663 ATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTL 715
>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
Length = 947
Score = 607 bits (1565), Expect = e-173
Identities = 314/713 (44%), Positives = 460/713 (64%), Gaps = 9/713 (1%)
Query: 5 AWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSAR 64
+W SG S R++ +LLLL A + +HY + EE + G VG + +LGL+L L R
Sbjct: 4 SWGSGQESR-RLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR 62
Query: 65 RFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVV 124
FRV S EVN + G +FVN R+DREELC C++ LE++V+ PL++F V+V
Sbjct: 63 LFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVE 122
Query: 125 IQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRV 184
++DINDN P FP + L I+E+ +RFPLE A D D+G N+L TY LS NEYF+L
Sbjct: 123 VRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEK 182
Query: 185 QTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVF 244
++ K L+L ++LDRE P + LVLTA DGG P L+ ++ + I VLDANDNAP F
Sbjct: 183 PPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAF 242
Query: 245 NQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGML 304
++++Y+ R+LE+ P+GT V+++ A+DLDEG NG+I+YSF + V+ F +D +TG +
Sbjct: 243 DRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQI 302
Query: 305 TIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPED 364
+KG +DFE++K +EI ++ DKG P HC+V+VEV D NDN P++ S+ P+ ED
Sbjct: 303 IVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIRED 362
Query: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYN 424
APLGTVIAL+SV+D D G NGLVTC + +PF L S+ KNY++L + LDRE+V Y
Sbjct: 363 APLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYE 422
Query: 425 LSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDP 484
L +TARD G+PSL A V V+V+D+NDN P +Q Y V+++ENN PG I +S WD
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482
Query: 485 DAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGT 544
DA +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGV 542
Query: 545 PVLATNISVNIFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAG 601
P L +N+++ +FV D NDNAP +L PR GG+ E++P GH+V++V DAD+G
Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSG 602
Query: 602 HNAWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTT 659
+NAWLSY L + F +GL+TG+IST R + +TD+PR L VL+KD+GEP+L+ T
Sbjct: 603 YNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTAT 662
Query: 660 ATLTVSVTE--DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
AT+ VS+ E +P+A + G+ P ++ YL++++ VS V+T+
Sbjct: 663 ATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTL 715
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 605 bits (1560), Expect = e-173
Identities = 334/788 (42%), Positives = 487/788 (61%), Gaps = 16/788 (2%)
Query: 9 GLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV 68
GLV G ++G L G T I Y +PEE EKG VG++ +LGL+ L+ R R+
Sbjct: 12 GLVLLGILLGTLWETGC-----TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRI 66
Query: 69 VSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDI 128
+ + F +N +G + R+DREELC C + L++++E+ ++++ VEV ++DI
Sbjct: 67 IPRGRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDI 126
Query: 129 NDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTRE 188
NDN P F E++++ISE A RFPL A DPD+G NSLQ+YELS N +F+L VQ
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGA 186
Query: 189 DSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSL 248
D +KY ELVL+RALDRE + + LVLTA DGG P + + I + VLDANDNAP F Q
Sbjct: 187 DGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPE 246
Query: 249 YRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKG 308
YRA V E+ GT+++ V ATD DEG N E+ YSF + Q+F LD +G ++ G
Sbjct: 247 YRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIG 305
Query: 309 RLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLG 368
LD E++ +++ +QA D A KVL+ V+DVNDNAPE+ +TS+ S VPE++P G
Sbjct: 306 ELDHEESGFYQMEVQAMDNAG--YSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRG 363
Query: 369 TVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSIT 428
T+IALL+V D D+ ENG V C + LPF L S NY++L T LDRE VP YN+++T
Sbjct: 364 TLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVT 423
Query: 429 ARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQ 488
A D GTP LS T + + V+D NDNPP Q+SY YI ENN G +++++ DPD +
Sbjct: 424 ATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEE 483
Query: 489 NARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLA 548
NA++++ L E + + Y +IN D G++ +L DYE R+ ++ D G P L+
Sbjct: 484 NAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLS 543
Query: 549 TNISVNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAW 605
+N+S+++FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAW
Sbjct: 544 SNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAW 603
Query: 606 LSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVS 665
LSY LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+
Sbjct: 604 LSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 663
Query: 666 VTEDSPEARAEFPSGSAP-REQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSR 724
V + P+ A+ S +P + +LT YL++++ VS F+ V ++ ++ +W +SR
Sbjct: 664 VADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSR 723
Query: 725 DLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-HQVYLTTDSRRSDPLLKKPGAASPLA 783
L +A L T P+ H V G Y H+V LTTDSR+S + +P A L
Sbjct: 724 -LLQASGGGL--TGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLV 780
Query: 784 SRQNTLRS 791
S+++ +S
Sbjct: 781 SQESFEKS 788
>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
sapiens]
Length = 789
Score = 603 bits (1555), Expect = e-172
Identities = 316/698 (45%), Positives = 448/698 (64%), Gaps = 8/698 (1%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
+++L A +HY +PEE + G VG + +LGL+L L R FR V EV
Sbjct: 18 IIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ LE++VE PL++F V+V ++DINDN P FP +
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQ 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
L I+E+ +RFPLE A D D+G N+L TY LS NEYF L V T K LVL
Sbjct: 138 RNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
+ LDRE P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY ++ E+
Sbjct: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT V+ A+DLDEG NG+IIYSF S ++ F +D ++G +T+ G +DFE+++ H+
Sbjct: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I ++A DKG P HC VLVEVVDVNDNAP++T+TS+ P+PEDA GTVI L+SV D
Sbjct: 318 IPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDR 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
D G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
V V+V+D+NDN P +Q Y V+++ENN PG I +S D DA +NA +S+ L+E
Sbjct: 438 TASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVEL 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL--LGSP 614
NDNAP +L PR GG+ E++PR AGH+V++V DAD+G+NAWLSY L + +
Sbjct: 558 ENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAG 617
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
F +GL+TG+IST R + +TD+PR L VL+KD+GEPSL+ TAT+ VS+ E +P+
Sbjct: 618 ASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTV 709
A + G A P + ++ YL++++ VS V+T+
Sbjct: 678 ASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTL 715
>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 937
Score = 603 bits (1555), Expect = e-172
Identities = 316/698 (45%), Positives = 448/698 (64%), Gaps = 8/698 (1%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
+++L A +HY +PEE + G VG + +LGL+L L R FR V EV
Sbjct: 18 IIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ LE++VE PL++F V+V ++DINDN P FP +
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQ 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
L I+E+ +RFPLE A D D+G N+L TY LS NEYF L V T K LVL
Sbjct: 138 RNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
+ LDRE P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY ++ E+
Sbjct: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT V+ A+DLDEG NG+IIYSF S ++ F +D ++G +T+ G +DFE+++ H+
Sbjct: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I ++A DKG P HC VLVEVVDVNDNAP++T+TS+ P+PEDA GTVI L+SV D
Sbjct: 318 IPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDR 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
D G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
V V+V+D+NDN P +Q Y V+++ENN PG I +S D DA +NA +S+ L+E
Sbjct: 438 TASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVEL 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL--LGSP 614
NDNAP +L PR GG+ E++PR AGH+V++V DAD+G+NAWLSY L + +
Sbjct: 558 ENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAG 617
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
F +GL+TG+IST R + +TD+PR L VL+KD+GEPSL+ TAT+ VS+ E +P+
Sbjct: 618 ASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTV 709
A + G A P + ++ YL++++ VS V+T+
Sbjct: 678 ASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTL 715
>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 603 bits (1555), Expect = e-172
Identities = 346/818 (42%), Positives = 494/818 (60%), Gaps = 22/818 (2%)
Query: 14 GRVVGVLLLLGALNKAST-VIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
G ++ + LLG L + I Y +PEE +KG VGN+ +LGLD L+ R+VS
Sbjct: 11 GELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRG 70
Query: 73 SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
+ F +N +G + R+DREELC P C + + +VE+ +LF VE+ I DINDNN
Sbjct: 71 RTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130
Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
P F ++++++I+E PG R+PL A DPDVG NSLQ+Y+LS N +F+L VQT ++
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190
Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
ELVLERALDRE E + LVLTA DGG P S+++ IH+ VLD NDNAPVF +YR +
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250
Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
VLE+ P GTR++ V A+D DEG NG++ Y F N LF L+ TG ++I LD+
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRKINEKQT-PLFQLNENTGEISIAKSLDY 309
Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
E+ +E+ IQA+D GA K+L+ V DVNDN PE+ +TS++SPV E++ GTVIA
Sbjct: 310 EECSFYEMEIQAEDVGALL--GRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367
Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
LSV D D+G+NG V C LPF L S+ NY+ L T LDRE V YN+++ A D
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427
Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
GTP LS T + + V+DINDNPP +SY YI ENNL GA I +L+ DPD+ +NA++
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487
Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
++ + E + + Y +IN D G++ +L DYE R+ +L SD G P L++N+S
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547
Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
+++FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667
Query: 670 SPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
PE E S + +LT YL++++ +S F+ V ++ ++ +W +SR L
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQ- 726
Query: 729 APVSSLYRTPG-PSLHADAVRGGLMSPHLYHQ-VYLTTDSRRSDPLLKKPGAASPLASRQ 786
S R G P+ H V Y Q V LT DSR+S + +P A L S++
Sbjct: 727 ---DSGGRLVGVPASHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLISQE 783
Query: 787 ------NTLRSCDPVFYRQVL--GAESAPPGQVRFSKS 816
+ L S D Y+ G ++ P RFS++
Sbjct: 784 GCEKNDSLLTSVDFHEYKNEADHGQQAPPNTDWRFSQA 821
>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 602 bits (1553), Expect = e-172
Identities = 337/780 (43%), Positives = 479/780 (61%), Gaps = 14/780 (1%)
Query: 14 GRVVGVLLLLGALNKAST-VIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
G ++ + LLG L + I Y +PEE +KG VGN+ +LGLD L+ R+VS
Sbjct: 11 GELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRG 70
Query: 73 SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
+ F +N +G + R+DREELC P C + + +VE+ +LF VE+ I DINDNN
Sbjct: 71 RTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130
Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
P F ++++++I+E PG R+PL A DPDVG NSLQ+Y+LS N +F+L VQT ++
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190
Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
ELVLERALDRE E + LVLTA DGG P S+++ IH+ VLD NDNAPVF +YR +
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250
Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
VLE+ P GTR++ V A+D DEG NG++ Y F N LF L+ TG ++I LD+
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRKINEKQT-PLFQLNENTGEISIAKSLDY 309
Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
E+ +E+ IQA+D GA K+L+ V DVNDN PE+ +TS++SPV E++ GTVIA
Sbjct: 310 EECSFYEMEIQAEDVGALL--GRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367
Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
LSV D D+G+NG V C LPF L S+ NY+ L T LDRE V YN+++ A D
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427
Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
GTP LS T + + V+DINDNPP +SY YI ENNL GA I +L+ DPD+ +NA++
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487
Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
++ + E + + Y +IN D G++ +L DYE R+ +L SD G P L++N+S
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547
Query: 553 VNIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
+++FV D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667
Query: 670 SPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
PE E S + +LT YL++++ +S F+ V ++ ++ +W +SR L
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQ- 726
Query: 729 APVSSLYRTPG-PSLHADAVRGGLMSPHLYHQ-VYLTTDSRRSDPLLKKPGAASPLASRQ 786
S R G P+ H V Y Q V LT DSR+S + +P A L S++
Sbjct: 727 ---DSGGRLVGVPASHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLISQE 783
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 602 bits (1552), Expect = e-172
Identities = 311/706 (44%), Positives = 456/706 (64%), Gaps = 5/706 (0%)
Query: 19 VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76
+LLLL A++ + Y +PEE+ G VGNV LGL+L L R+ + S R+
Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
Query: 77 FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136
E++ +G +FVN+R+DRE LC P C ++LE++ NP+ + +VEV I DINDN+P FP
Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
Query: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196
+L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++ ++++K EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
Query: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256
VL + LDRE+ LVLTA+DGG PA S + I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
Query: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316
+P GT VV++ A+D DEG NGE+ YS S+ RQLF++D TG + + G LD+E+
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
Query: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376
++IY+QA D+G P HCKVLV++VDVNDNAPE+ +T +YSPVPE+A T++A+LSV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
Query: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436
D D+G N V+ + LPF L + N +TL S LDRE V YN+++TA D G P
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
Query: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496
L++L ++V++SDINDNPP + SY +YI+ENNLPG + + DPD +NA +++ L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
Query: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556
LE+ + V Y +IN +G + ++ DYE REF +T D G+P L++ ++ N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
Query: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
V D ND+AP +LYP SS EM+PR AG+LV++V+ D+D+G NAWL Y L +
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
+ LF + LHTG+I T R + D LTV+++DNGEPSLS + +TV+V + +
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
Query: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
+ +T YL+++L VS F++T+ + I K Y++
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 602 bits (1552), Expect = e-172
Identities = 311/706 (44%), Positives = 456/706 (64%), Gaps = 5/706 (0%)
Query: 19 VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76
+LLLL A++ + Y +PEE+ G VGNV LGL+L L R+ + S R+
Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
Query: 77 FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136
E++ +G +FVN+R+DRE LC P C ++LE++ NP+ + +VEV I DINDN+P FP
Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
Query: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196
+L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++ ++++K EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
Query: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256
VL + LDRE+ LVLTA+DGG PA S + I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
Query: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316
+P GT VV++ A+D DEG NGE+ YS S+ RQLF++D TG + + G LD+E+
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
Query: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376
++IY+QA D+G P HCKVLV++VDVNDNAPE+ +T +YSPVPE+A T++A+LSV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
Query: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436
D D+G N V+ + LPF L + N +TL S LDRE V YN+++TA D G P
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
Query: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496
L++L ++V++SDINDNPP + SY +YI+ENNLPG + + DPD +NA +++ L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
Query: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556
LE+ + V Y +IN +G + ++ DYE REF +T D G+P L++ ++ N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
Query: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
V D ND+AP +LYP SS EM+PR AG+LV++V+ D+D+G NAWL Y L +
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
+ LF + LHTG+I T R + D LTV+++DNGEPSLS + +TV+V + +
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
Query: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
+ +T YL+++L VS F++T+ + I K Y++
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 601 bits (1550), Expect = e-172
Identities = 313/703 (44%), Positives = 455/703 (64%), Gaps = 8/703 (1%)
Query: 15 RVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASR 74
R++ + LLL S +HY IPEE + G VG + +LGL+L L R FRV S
Sbjct: 12 RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRG 71
Query: 75 RFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPA 134
EVN + G +FVN R+DREELC C++ LE++V+ PL++F VEV ++DINDN P
Sbjct: 72 DLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPR 131
Query: 135 FPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYA 194
F QE +L I E+ P +RFPLE A D D+G+N+ Y L+ NEYF L V+T E+ T +
Sbjct: 132 FSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFL 191
Query: 195 ELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVL 254
ELVL ++LDRE +L++ A DGG P L+ ++ + I VLDANDNAP F++S+Y R+L
Sbjct: 192 ELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLL 251
Query: 255 EDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFED 314
E+APSGT V+++ A+D DEG N EI+Y F + V+ F ++ TG + + G LD+ED
Sbjct: 252 ENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYED 311
Query: 315 TKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALL 374
+EI I A DK P HCKV+V+++DVNDN PE+ +T+++ PV EDAPL TVIAL+
Sbjct: 312 YNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALI 371
Query: 375 SVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGT 434
SV+D D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+
Sbjct: 372 SVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGS 431
Query: 435 PSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSF 494
PSL A V V+V+D+NDN P +Q Y V+++ENN PG I +S D DA +NA +S+
Sbjct: 432 PSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSY 491
Query: 495 FLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVN 554
L+E+ + Y +++ ++G V +L PLD+E+ + D G P L +N+++
Sbjct: 492 SLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQ 551
Query: 555 IFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL 611
+FV D NDNAP +L PR GG+ E++PR AGH+V++V D D+G+NAWLSY L
Sbjct: 552 VFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQ 611
Query: 612 GSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE- 668
+P + F +GL+TG+IST R + +T++PR L VL+KD+GEP L+ TAT+ VS+ E
Sbjct: 612 PAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES 671
Query: 669 -DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
+P+A + +G+ P ++ YL++++ VS V+T+
Sbjct: 672 GQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTL 714
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 601 bits (1550), Expect = e-172
Identities = 313/703 (44%), Positives = 455/703 (64%), Gaps = 8/703 (1%)
Query: 15 RVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASR 74
R++ + LLL S +HY IPEE + G VG + +LGL+L L R FRV S
Sbjct: 12 RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRG 71
Query: 75 RFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPA 134
EVN + G +FVN R+DREELC C++ LE++V+ PL++F VEV ++DINDN P
Sbjct: 72 DLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPR 131
Query: 135 FPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYA 194
F QE +L I E+ P +RFPLE A D D+G+N+ Y L+ NEYF L V+T E+ T +
Sbjct: 132 FSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFL 191
Query: 195 ELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVL 254
ELVL ++LDRE +L++ A DGG P L+ ++ + I VLDANDNAP F++S+Y R+L
Sbjct: 192 ELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLL 251
Query: 255 EDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFED 314
E+APSGT V+++ A+D DEG N EI+Y F + V+ F ++ TG + + G LD+ED
Sbjct: 252 ENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYED 311
Query: 315 TKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALL 374
+EI I A DK P HCKV+V+++DVNDN PE+ +T+++ PV EDAPL TVIAL+
Sbjct: 312 YNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALI 371
Query: 375 SVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGT 434
SV+D D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+
Sbjct: 372 SVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGS 431
Query: 435 PSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSF 494
PSL A V V+V+D+NDN P +Q Y V+++ENN PG I +S D DA +NA +S+
Sbjct: 432 PSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSY 491
Query: 495 FLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVN 554
L+E+ + Y +++ ++G V +L PLD+E+ + D G P L +N+++
Sbjct: 492 SLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQ 551
Query: 555 IFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL 611
+FV D NDNAP +L PR GG+ E++PR AGH+V++V D D+G+NAWLSY L
Sbjct: 552 VFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQ 611
Query: 612 GSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE- 668
+P + F +GL+TG+IST R + +T++PR L VL+KD+GEP L+ TAT+ VS+ E
Sbjct: 612 PAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES 671
Query: 669 -DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709
+P+A + +G+ P ++ YL++++ VS V+T+
Sbjct: 672 GQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTL 714
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,398,928
Number of Sequences: 37866
Number of extensions: 1555611
Number of successful extensions: 10538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3511
Number of HSP's gapped (non-prelim): 707
length of query: 863
length of database: 18,247,518
effective HSP length: 111
effective length of query: 752
effective length of database: 14,044,392
effective search space: 10561382784
effective search space used: 10561382784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.