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Search of human proteins with 14277675
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14277675 protocadherin gamma subfamily C, 3 isoform 1
precursor [Homo sapiens]
(934 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs... 1848 0.0
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 1594 0.0
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 881 0.0
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 871 0.0
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 867 0.0
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 866 0.0
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 866 0.0
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 865 0.0
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 853 0.0
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 853 0.0
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 849 0.0
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 848 0.0
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 845 0.0
gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs... 843 0.0
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs... 829 0.0
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 828 0.0
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 824 0.0
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 823 0.0
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 820 0.0
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs... 814 0.0
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 812 0.0
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs... 803 0.0
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 631 e-180
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 629 e-180
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 627 e-179
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 626 e-179
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 626 e-179
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 622 e-178
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 620 e-177
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 620 e-177
>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
[Homo sapiens]
Length = 934
Score = 1848 bits (4788), Expect = 0.0
Identities = 934/934 (100%), Positives = 934/934 (100%)
Query: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
Sbjct: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
Query: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
Sbjct: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
Sbjct: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
Sbjct: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
Sbjct: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
Sbjct: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
Sbjct: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
Sbjct: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
Sbjct: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
Sbjct: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
Query: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
Sbjct: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
Query: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
Sbjct: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 840
PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 840
Query: 841 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 900
PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
Sbjct: 841 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 900
Query: 901 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 901 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
[Homo sapiens]
Length = 863
Score = 1594 bits (4128), Expect = 0.0
Identities = 810/810 (100%), Positives = 810/810 (100%)
Query: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
Sbjct: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
Query: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
Sbjct: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
Sbjct: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
Sbjct: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
Sbjct: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
Sbjct: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
Sbjct: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
Sbjct: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
Sbjct: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
Sbjct: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA 600
Query: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
Sbjct: 601 GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
Query: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
Sbjct: 661 TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720
Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQ 810
PLASRQNTLRSCDPVFYRQVLGAESAPPGQ
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQ 810
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 881 bits (2277), Expect = 0.0
Identities = 478/926 (51%), Positives = 621/926 (67%), Gaps = 12/926 (1%)
Query: 15 RVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
R++ + LLLG L + + I Y + EE+E+G VGN+ +LGL L+ R R+VS
Sbjct: 12 RLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGR 71
Query: 74 RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
+ F +N +G + R+DREELC P+C LE+++E+ +++ VEV I D+NDN P
Sbjct: 72 TQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPP 131
Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
+F T++ +++++E PG RFPL A DPDVG NSLQ Y+L+ N YF+L VQ+ D KY
Sbjct: 132 SFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKY 191
Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
ELVLERALDRE E LVLTA DGG P S + I I ++D NDNAPVF Q Y V
Sbjct: 192 PELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSV 251
Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
E+ P GTR++ V ATD DEG NG++ YSF R + QLF L+ ++G +TI G LD+E
Sbjct: 252 RENVPVGTRLLTVKATDPDEGANGDVTYSFRKV-RDKISQLFQLNSLSGDITILGGLDYE 310
Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
D+ ++I ++A D A KVLV V+D NDNAPE+TVTS+ S V E + GTVIAL
Sbjct: 311 DSGFYDIDVEAHDGPGLR--ARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIAL 368
Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
+V D D+G NGLVTC +P LPF+L + NY+ L T LDRE V EYN+++TA D G
Sbjct: 369 FNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQG 428
Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
TP LS T + +QV DINDNPP +SY YI ENN GA IL+++ DPD+ NAR++
Sbjct: 429 TPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARIT 488
Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
+ L E + + Y +IN + GI+ +L DYE R+ +L SD G P L++N+S+
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSL 548
Query: 554 NIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
++FV D+NDN P++LYP G + VE+ PR +G+LV++VV D D+G NAWLSYSL
Sbjct: 549 SLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSL 608
Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
L S LFA+GLHTG++ TAR + D D+ +Q L V+++D+G+P LS T TLTV+V +
Sbjct: 609 LKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSI 668
Query: 671 PEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRA 729
P+ A+ S + LT YL++++ VS F+ V ++ K+ +W +SR L A
Sbjct: 669 PDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSR-LLHA 727
Query: 730 PVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNT 788
S L P + D VR L + H+V LT DSR+S + +P A L SR++
Sbjct: 728 EGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFSQPSYADTLISRESC 785
Query: 789 LRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE 848
+S + + +L + P QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE
Sbjct: 786 EKSEPLLITQDLLETKGDPNLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE 845
Query: 849 MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN 908
MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN
Sbjct: 846 MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN 905
Query: 909 AAGKRDGKAPAGGNGNKKKSGKKEKK 934
AAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 906 AAGKRDGKAPAGGNGNKKKSGKKEKK 931
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 871 bits (2251), Expect = 0.0
Identities = 470/924 (50%), Positives = 615/924 (66%), Gaps = 15/924 (1%)
Query: 19 VLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFF 77
+L LLG L A+ I Y IPEE EKG VGN+V +LGL+ L+ R+VS + F
Sbjct: 16 LLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLF 75
Query: 78 EVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPT 137
+N G + R+DREELC P C V+ ++VE+ L L+ VEV I DINDN P F
Sbjct: 76 SLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLK 135
Query: 138 QEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELV 197
+E++++I E AP +RFPL +DPDVG NSLQ ++LS N +F++ VQ+ KY ELV
Sbjct: 136 EELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELV 195
Query: 198 LERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDA 257
LE LDRE E +LVLTA+DGG P S+ I + VLD NDN P+F Q +YR V E+
Sbjct: 196 LEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENL 255
Query: 258 PSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKL 317
P GT V+ V ATD DEG +GE+ YSF + Q+F L+++TG ++ LD+ED+
Sbjct: 256 PVGTPVLAVTATDQDEGVHGEVTYSFVKITEK-ISQIFCLNVLTGEISTSANLDYEDSSF 314
Query: 318 HEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVT 377
+E+ ++A+D + A KVL+ ++DVNDN PE+ VTS + E AP GTVIAL V
Sbjct: 315 YELGVEARDGPGLRDRA--KVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVF 372
Query: 378 DLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSL 437
D D+G NGLVTC +P LPF L S+ NY+ L T+A LDRE V YN+++TA D GTP L
Sbjct: 373 DRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPL 432
Query: 438 SALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLL 497
S TI+ + V+D NDNPP SSY VY+ ENN GA I +++ DPD QNA++S+ L
Sbjct: 433 STETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLA 492
Query: 498 EQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFV 557
E + + Y +IN D GI+ +L DYE R+ +L SD G P L++N+S+++FV
Sbjct: 493 EDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFV 552
Query: 558 TDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
D+NDNAP++LYP G + VE+ PR G+LV++VV D D+G NAWLSY LL +
Sbjct: 553 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 612
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+
Sbjct: 613 EPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDIL 672
Query: 675 AEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSS 733
A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L +A
Sbjct: 673 ADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSR-LLQASGGG 731
Query: 734 LYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSC 792
L PG + + VR L + H+V LT DSR+S + +P A L ++++ +S
Sbjct: 732 LASMPGSHFVGVEGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKS- 788
Query: 793 DPVFYRQVLGAESAPPGQ--QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEML 850
+P+ Q L P Q QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEML
Sbjct: 789 EPLLITQDLLETKGEPRQLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEML 848
Query: 851 QAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAA 910
QAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAA
Sbjct: 849 QAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAA 908
Query: 911 GKRDGKAPAGGNGNKKKSGKKEKK 934
GKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 909 GKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 867 bits (2240), Expect = 0.0
Identities = 465/911 (51%), Positives = 618/911 (67%), Gaps = 16/911 (1%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y +PEE EKG VGN+ +LGL+ L+ R R+VS + F VN +G + R+
Sbjct: 32 IRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRI 91
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREELC T+ SC + +EL+VE+ L+++ VEV I DINDN P+F E+++++SE PG
Sbjct: 92 DREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGA 151
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RF L +A DPDVG NSLQ+Y+LS N YF+L+++ R D K ELVLE +LDRE+E + L
Sbjct: 152 RFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLL 211
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
+LTALDGG P ++PI + VLD ND+ P+F QS+YR V E+ SGTRV+ V ATD D
Sbjct: 212 LLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPD 271
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE++YSF + + ++F LD TG + ++G LDFE + +E+ IQ +D G
Sbjct: 272 EGINGEVMYSF-RNMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGGL-- 328
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
+L+ VVDVNDNAPEIT+TS + + E++P GTVIALL+V D D+GENG V+C +P
Sbjct: 329 FTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIP 388
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L + NY+ L TS LDRE V YN+++TA D G+P LSA T V + V+D ND
Sbjct: 389 NHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDND 448
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SSY YI ENN GA I +++ DPD+ QNA +++ L + + + Y +I
Sbjct: 449 NPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI 508
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPR- 571
N + G++ +L DYE R+ EL D G P L++N+S+++FV D+NDNAP++LYP
Sbjct: 509 NSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 568
Query: 572 --PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
G + VE+ PR G+LV++VV D D+G NAWLSY LL + LFA+G HTG++
Sbjct: 569 PTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 628
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPS-GSAPREQKK 688
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + PE A+ S S +
Sbjct: 629 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETS 688
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADAV 747
+L+ YL++++ VS F+V V ++ ++++W +SR L +A L P + D V
Sbjct: 689 DLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSR-LLQASEGGLAGMPTSHFVGVDGV 747
Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQ----VLGA 803
+ L + H+V L DS++S + +P L S+++ +S +P+ + +LG
Sbjct: 748 QAFLQT--YSHEVSLIADSQKSHLIFPQPNYGDTLISQESCEKS-EPLLIAEDSAIILGK 804
Query: 804 ESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAAD 863
QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAAD
Sbjct: 805 CDPTSNQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAAD 864
Query: 864 GSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNG 923
GSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNG
Sbjct: 865 GSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNG 924
Query: 924 NKKKSGKKEKK 934
NKKKSGKKEKK
Sbjct: 925 NKKKSGKKEKK 935
>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 866 bits (2237), Expect = 0.0
Identities = 462/930 (49%), Positives = 621/930 (66%), Gaps = 17/930 (1%)
Query: 14 GRVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
GR+V + LLG L +A ++ I Y +PEE EKG+ VGN+ +L L+ L+ RR R+VS
Sbjct: 11 GRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRG 70
Query: 73 SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
+ F +N +G + R+DREELC P C V +++VE+ ++L+ +E+ + DIND+
Sbjct: 71 RTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130
Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
P F + ++++I+E PG R+PL A DPDVG NSLQ+Y+LS N +F+L VQT ++
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190
Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
ELVLERALDRE + LVLTA DGG P S+++ IH+ VLD NDNAPVF Q +YR +
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250
Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
VLE+ P GT ++ A+DLDEG NG++ Y F N LF L+ TG ++ LD+
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEKQ-SLLFQLNENTGEISTAKSLDY 309
Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
E+ +E+ IQA+D G KVL+ V DVNDN PE+T+TS++SPV EDAP GTVI
Sbjct: 310 EECSFYEMEIQAEDGGGLK--GWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367
Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
L + D D+G+NG V C + L F+L +S ++Y+ L T+ LDRE EYN+++TA D
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427
Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
GTP LS + +QV+DINDNPP SQ+SY VY+ ENN G I ++ +DPD+ +N+R+
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487
Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
+ L E + + Y +IN D G++ +L DYE R+ ++ SD G+P L++N+S
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547
Query: 553 VNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
+ +FV D+NDNAP++LYP G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
L + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV++ +
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667
Query: 670 SPEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
P+ A+ S P + + +LT YL++++ +VS F+ V ++ ++ W S L R
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWHSSH-LLR 726
Query: 729 APVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVY-LTTDSRRSDPLLKKPGAASPLASRQ 786
A L P + D VR L + Y Q + LT DSR+S + +P A L S+Q
Sbjct: 727 ATSDGLAGVPTSHFVGVDGVRAFLQT---YSQEFSLTADSRKSHLIFPQPNYADTLISQQ 783
Query: 787 NTLRSCDP--VFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 844
+ ++ +P V E P QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ
Sbjct: 784 SCEKN-EPLCVSVDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 842
Query: 845 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 904
FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA
Sbjct: 843 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 902
Query: 905 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 903 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 866 bits (2237), Expect = 0.0
Identities = 470/930 (50%), Positives = 622/930 (66%), Gaps = 16/930 (1%)
Query: 14 GRVVGVLL-LLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSG 71
GR + +L LLG L S I Y + EE +KG VGN+ +LGL+ L+ R R+VS
Sbjct: 10 GRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSR 69
Query: 72 ASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDN 131
+ F +N ++G + +R+DREELC +P C V + ++VE+ L++F VE+ I+DINDN
Sbjct: 70 GRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDN 129
Query: 132 NPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDST 191
P FPT+E++++I E PGTRFP+++A DPDVG NSLQ Y+LS N+YF+L V + +
Sbjct: 130 APNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGA 189
Query: 192 KYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRA 251
KY ELVLERALDRE++ QLVL A DGG P S +L I + VLDANDN P+F Q YR
Sbjct: 190 KYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRV 249
Query: 252 RVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLD 311
V E+ P GTR++ V ATD DEG N ++ Y + ++F L+ V+G ++I LD
Sbjct: 250 SVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMP-GKIAEIFHLNSVSGEVSILKSLD 308
Query: 312 FEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVI 371
+ED +EI I+A+D A K+LV V+DVNDNAPEIT+TS+ S VPE+ +G I
Sbjct: 309 YEDAMFYEIKIEAQDGPGLLSRA--KILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366
Query: 372 ALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARD 431
AL+ V D D+G+NG V V LPF L S+ Y+ L T+ LDRE + EYN+S+ A D
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASD 426
Query: 432 AGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNAR 491
G+P LS T + + V DINDNPP SY YI ENN GA I +++ DPD+ NAR
Sbjct: 427 GGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNAR 486
Query: 492 LSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNI 551
+++ L E + + + +IN + G++ +L DYE R+ +L SD G P L++N+
Sbjct: 487 ITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Query: 552 SVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSY 608
S+N+FV D+NDNAP++LYP G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 547 SLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSY 606
Query: 609 SLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE 668
LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Query: 669 DSPEARAEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLY 727
P+ A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L
Sbjct: 667 RIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSR-LL 725
Query: 728 RAPVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQ 786
+A L TPG + AD VR L + H+V LT DSR+S + +P A L S++
Sbjct: 726 QASGGGLASTPGSHFVGADGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQE 783
Query: 787 NTLRSCDPVFYRQVLGAESAPPG--QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 844
+ +S +P+ Q L QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ
Sbjct: 784 SCEKS-EPLLITQDLLEMKGDSNLLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 842
Query: 845 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 904
FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA
Sbjct: 843 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 902
Query: 905 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 903 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 865 bits (2236), Expect = 0.0
Identities = 466/909 (51%), Positives = 609/909 (66%), Gaps = 14/909 (1%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y IPEE EKG VGN+ +LGL L+ R R+VS + F +N +G + R+
Sbjct: 35 ISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRI 94
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREELC C V+ ++VE+ ++LF +E+ + DINDN P F + + ++I+E VA G
Sbjct: 95 DREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGM 154
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RFPL A DPDVG NSLQ+Y+LS N++F+LRVQ+R + KY ELVLE +LDRE E L
Sbjct: 155 RFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHL 214
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTA DGG P S ++ + + V DANDNAPVF YR V E+ P GT+++ V ATD D
Sbjct: 215 VLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRD 274
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE+ YSF + + F L+ TG + I LD+E+T +EI IQA+D GA
Sbjct: 275 EGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYL- 332
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
A KVL+ V DVNDN+PE+T+TS++SPV ED+PLGTV+ALL+V DLD+ +NG VTC +
Sbjct: 333 -ATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL 391
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L S+ +Y+ L LDRE V YN+++TA D G+P LS +QV+DIND
Sbjct: 392 AYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADIND 451
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SQ SY YI ENN GA I +++ DPD+ +NA++ + L E + + Y +I
Sbjct: 452 NPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISI 511
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPR- 571
N D G++ +L DYE E ++ SD G P L++N+S+++FV D+NDNAP++LYP
Sbjct: 512 NSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPAL 571
Query: 572 --PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
G + VE+ PR G+LV++VV D D+G NAWLSY LL + LFA+G HTG++
Sbjct: 572 PTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVR 631
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAP-REQKK 688
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+ A+ S +P +
Sbjct: 632 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETS 691
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADAV 747
+LT YL++++ VS F+ V ++ ++ +W +SR L +A L G + D V
Sbjct: 692 DLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSR-LLQASGGGLTGVSGSHFVGVDGV 750
Query: 748 RGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQ--VLGAES 805
R L + H+V LT DSR+S + +P A L S+++ ++ DP+ E
Sbjct: 751 RAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKN-DPLSLLDDSKFPIED 807
Query: 806 APPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGS 865
P QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGS
Sbjct: 808 TPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGS 867
Query: 866 STLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK 925
STLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK
Sbjct: 868 STLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK 927
Query: 926 KKSGKKEKK 934
KKSGKKEKK
Sbjct: 928 KKSGKKEKK 936
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 853 bits (2203), Expect = 0.0
Identities = 461/933 (49%), Positives = 618/933 (66%), Gaps = 19/933 (2%)
Query: 9 GLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV 68
GLV G ++G L G T I Y +PEE EKG VG++ +LGL+ L+ R R+
Sbjct: 12 GLVLLGILLGTLWETGC-----TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRI 66
Query: 69 VSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDI 128
+ + F +N +G + R+DREELC C + L++++E+ ++++ VEV ++DI
Sbjct: 67 IPRGRTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDI 126
Query: 129 NDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTRE 188
NDN P F E++++ISE A RFPL A DPD+G NSLQ+YELS N +F+L VQ
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGA 186
Query: 189 DSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSL 248
D +KY ELVL+RALDRE + + LVLTA DGG P + + I + VLDANDNAP F Q
Sbjct: 187 DGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPE 246
Query: 249 YRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKG 308
YRA V E+ GT+++ V ATD DEG N E+ YSF + Q+F LD +G ++ G
Sbjct: 247 YRASVPENLALGTQLLVVNATDPDEGVNAEVRYSFRYVDDKAA-QVFKLDCNSGTISTIG 305
Query: 309 RLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLG 368
LD E++ +++ +QA D A KVL+ V+DVNDNAPE+ +TS+ S VPE++P G
Sbjct: 306 ELDHEESGFYQMEVQAMDNAGY--SARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRG 363
Query: 369 TVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSIT 428
T+IALL+V D D+ ENG V C + LPF L S NY++L T LDRE VP YN+++T
Sbjct: 364 TLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVT 423
Query: 429 ARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQ 488
A D GTP LS T + + V+D NDNPP Q+SY YI ENN G +++++ DPD +
Sbjct: 424 ATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEE 483
Query: 489 NARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLA 548
NA++++ L E + + Y +IN D G++ +L DYE R+ ++ D G P L+
Sbjct: 484 NAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLS 543
Query: 549 TNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAW 605
+N+S+++FV D+NDNAP++LYP G + VE+ PR G+LV++VV D D+G NAW
Sbjct: 544 SNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAW 603
Query: 606 LSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVS 665
LSY LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+
Sbjct: 604 LSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 663
Query: 666 VTEDSPEARAEFPSGSAP-REQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSR 724
V + P+ A+ S +P + +LT YL++++ VS F+ V ++ ++ +W +SR
Sbjct: 664 VADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSR 723
Query: 725 DLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-HQVYLTTDSRRSDPLLKKPGAASPLA 783
L +A L T P+ H V G Y H+V LTTDSR+S + +P A L
Sbjct: 724 -LLQASGGGL--TGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLV 780
Query: 784 SRQNTLRSCDPVFYR--QVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWP 841
S+++ +S +P+ V +S +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWP
Sbjct: 781 SQESFEKS-EPLLLSGDSVFSKDSHGLIEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWP 839
Query: 842 NNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPG 901
NNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPG
Sbjct: 840 NNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPG 899
Query: 902 SNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
SNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 900 SNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 853 bits (2203), Expect = 0.0
Identities = 468/934 (50%), Positives = 612/934 (65%), Gaps = 25/934 (2%)
Query: 14 GRVVGVLLLLGALNKAST-VIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGA 72
G ++ + LLG L + I Y +PEE +KG VGN+ +LGLD L+ R+VS
Sbjct: 11 GELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRG 70
Query: 73 SRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNN 132
+ F +N +G + R+DREELC P C + + +VE+ +LF VE+ I DINDNN
Sbjct: 71 RTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130
Query: 133 PAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTK 192
P F ++++++I+E PG R+PL A DPDVG NSLQ+Y+LS N +F+L VQT ++
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190
Query: 193 YAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRAR 252
ELVLERALDRE E + LVLTA DGG P S+++ IH+ VLD NDNAPVF +YR +
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250
Query: 253 VLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDF 312
VLE+ P GTR++ V A+D DEG NG++ Y F N LF L+ TG ++I LD+
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRKINEKQT-PLFQLNENTGEISIAKSLDY 309
Query: 313 EDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIA 372
E+ +E+ IQA+D GA K+L+ V DVNDN PE+ +TS++SPV E++ GTVIA
Sbjct: 310 EECSFYEMEIQAEDVGALL--GRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367
Query: 373 LLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDA 432
LSV D D+G+NG V C LPF L S+ NY+ L T LDRE V YN+++ A D
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427
Query: 433 GTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARL 492
GTP LS T + + V+DINDNPP +SY YI ENNL GA I +L+ DPD+ +NA++
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487
Query: 493 SFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNIS 552
++ + E + + Y +IN D G++ +L DYE R+ +L SD G P L++N+S
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547
Query: 553 VNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYS 609
+++FV D+NDNAP++LYP G + VE+ PR G+LV++VV D D+G NAWLSY
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607
Query: 610 LLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTED 669
LL + LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V +
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667
Query: 670 SPEARAEFPSGSAPREQK-KNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYR 728
PE E S + +LT YL++++ +S F+ V ++ ++ +W +SR L
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQ- 726
Query: 729 APVSSLYRTPG-PSLHADAVRGGLMSPHLYHQ-VYLTTDSRRSDPLLKKPGAASPLASRQ 786
S R G P+ H V Y Q V LT DSR+S + +P A L S++
Sbjct: 727 ---DSGGRLVGVPASHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLISQE 783
Query: 787 ------NTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 840
+ L S D Y+ A GQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
Sbjct: 784 GCEKNDSLLTSVDFHEYKN-----EADHGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 838
Query: 841 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 900
PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
Sbjct: 839 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 898
Query: 901 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 899 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 849 bits (2194), Expect = 0.0
Identities = 456/911 (50%), Positives = 611/911 (67%), Gaps = 18/911 (1%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y + EE +KG VG++ +LGL+ L+ R R++S + F +N+ +G + R+
Sbjct: 31 ILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAGRI 90
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREE+C C V +++E+ + L+ ++V I DINDN P F T+E+ ++I E APG
Sbjct: 91 DREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGV 150
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RFPL A DPDVG+NSLQ+Y+LS N +F+L VQ+ +D TKY ELVLER LDRE E L
Sbjct: 151 RFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHL 210
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTA DGG P S++ I + V+D ND+ PVF+ Y+ V E+ P GTR++ V A DLD
Sbjct: 211 VLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLD 270
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NGE+ YSF + ++F L+ +TG ++ LD+E+T +E+ +QA+D +
Sbjct: 271 EGVNGEVTYSFRKITPK-LPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLT 329
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
A KVL+ V+DVNDNAPE+T+TS+ S +PED PLGTVIAL + D D+G+NG VTC +P
Sbjct: 330 KA--KVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIP 387
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
LPF L S+ NY+ L T+ +LDRET+ YN+++ A D GTP LS T + +QV+D ND
Sbjct: 388 ENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTND 447
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
NPP SSY VYI ENN GA I ++ D D+ NA++++ L E + V Y +I
Sbjct: 448 NPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSI 507
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPR- 571
N D G++ +L DYE RE +L D G P L++N+S+++FV D+NDN P++LYP
Sbjct: 508 NSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPAL 567
Query: 572 --PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
G + +E+ PR G+LV++VV D D+G NAWLSY LL + LFA+GL+TG++
Sbjct: 568 PTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVR 627
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKN 689
TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + PE A+ S P + N
Sbjct: 628 TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGS-LEPSDGPYN 686
Query: 690 --LTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPS-LHADA 746
LT YL++++ VS F+ V ++ ++ +W +SR L +A L P + D
Sbjct: 687 YDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHKSR-LLQASEGGLANVPTSHFVGMDG 745
Query: 747 VRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS---CDPVFYRQVLGA 803
V+ L + H+V LT DSR+S + +P L S+++ ++ V +++
Sbjct: 746 VQAFLQT--YSHEVSLTADSRKSHLIFPQPNYVDMLISQESCEKNDSLLTSVDFQEC--K 801
Query: 804 ESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAAD 863
E+ P QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAAD
Sbjct: 802 ENLPSIQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAAD 861
Query: 864 GSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNG 923
GSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNG
Sbjct: 862 GSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNG 921
Query: 924 NKKKSGKKEKK 934
NKKKSGKKEKK
Sbjct: 922 NKKKSGKKEKK 932
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 848 bits (2191), Expect = 0.0
Identities = 459/938 (48%), Positives = 615/938 (65%), Gaps = 17/938 (1%)
Query: 3 PEAWRSGLVSTGRVVGVLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSL 61
P W G ++ +LLG L S I Y +PEE +KG VGN+ +LGL+ L
Sbjct: 5 PRGW-----GCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQEL 59
Query: 62 SARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSV 121
+ R R+VS + F +N +G + R+DREELC P C V ++VEN ++++ V
Sbjct: 60 AERGVRIVSRGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGV 119
Query: 122 EVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFA 181
EV I DINDN P F +E+K++++E A GTR L A D DVG NSL++Y+LS N +F+
Sbjct: 120 EVEIIDINDNFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFS 179
Query: 182 LRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNA 241
L V + D KY ELVLE+ LDRE+E L+LTALDGG P LS + I + VLDANDNA
Sbjct: 180 LDVVSGTDGQKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNA 239
Query: 242 PVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVT 301
P+F S Y V E+ P GTR++ + ATD DEG NG++ YSF + + + F LD
Sbjct: 240 PLFTPSEYSVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEEK-ISETFQLDSNL 298
Query: 302 GMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPV 361
G ++ LD+E+++ + + + A+D GA A KV+V V DVNDNAPE+ +TS+ S +
Sbjct: 299 GEISTLQSLDYEESRFYLMEVVAQDGGALVASA--KVVVTVQDVNDNAPEVILTSLTSSI 356
Query: 362 PEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVP 421
ED GTVIAL SV D D+GENG + C +P LPF L S+ NY+ L T+ DLDRE
Sbjct: 357 SEDCLPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETS 416
Query: 422 EYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSV 481
+YN+++T D GTP LS + + ++V+D+NDNPP Q+SY + ENN G I +++
Sbjct: 417 DYNITLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTA 476
Query: 482 WDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISD 541
DPD+ NAR+++ L E + + Y +IN D G++ +L DYE R+ +L SD
Sbjct: 477 HDPDSGDNARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASD 536
Query: 542 GGTPVLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDA 598
G P L++N+S+++FV D+NDN P++LYP G + VE+ PR G+LV++VV D
Sbjct: 537 SGNPPLSSNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDK 596
Query: 599 DAGHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLST 658
D+G NAWLSY LL + LFA+GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSA 656
Query: 659 TATLTVSVTEDSPEARAEFPSGSAPREQKK-NLTFYLLLSLILVSVGFVVTVFGVIIFKV 717
T T+TV+V + P+ A+ S P + + +LT YL++++ VS F+ V +++ ++
Sbjct: 657 TFTVTVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRL 716
Query: 718 YKWKQSRDLYRAPVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKP 776
+W +SR L +A S L P + D VR L + H+V LT DSR+S + +P
Sbjct: 717 RRWHKSR-LLQAEGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFPQP 773
Query: 777 GAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDD 836
A L S ++ +S + +V + QQAPPNTDWRFSQAQRPGTSGSQNGDD
Sbjct: 774 NYADTLLSEESCEKSEPLLMSDKVDANKEERRVQQAPPNTDWRFSQAQRPGTSGSQNGDD 833
Query: 837 TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN 896
TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN
Sbjct: 834 TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN 893
Query: 897 VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 894 VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 931
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 845 bits (2182), Expect = 0.0
Identities = 458/921 (49%), Positives = 609/921 (66%), Gaps = 16/921 (1%)
Query: 19 VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFE 78
+LL GA N IHY +PEE +KG VGN+ +LGL L+ R+VS F
Sbjct: 22 LLLEAGAGN-----IHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFA 76
Query: 79 VNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQ 138
+N +G + R+DREELC C V+ ++VE+ ++LF VEV I DINDN P F +
Sbjct: 77 LNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLE 136
Query: 139 EMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVL 198
E++ +++E PGTR L D DVG NSLQ+Y+LS N +F+L VQ D ++ E+VL
Sbjct: 137 ELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVL 196
Query: 199 ERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAP 258
+ LDRE E L+LTA DGG P S +L I+I+V+DANDN P F Q+ Y V E+ P
Sbjct: 197 QSPLDREEEAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVP 256
Query: 259 SGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLH 318
GT+++ V ATD DEG NGE+ YSF + + V Q+F LD TG ++ K LDFE+ K++
Sbjct: 257 LGTQLLMVNATDPDEGANGEVTYSFHNVDHR-VAQIFRLDSYTGEISNKEPLDFEEYKMY 315
Query: 319 EIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTD 378
+ +QA+D GA A KVL++V+DVNDNAPE+T+TSV + VPE+ P GT+IAL+SV D
Sbjct: 316 SMEVQAQD-GAGLM-AKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHD 373
Query: 379 LDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLS 438
D+G+NG TC +P LPF L + NY+ L T LDRE + YN++ITA D GTP+LS
Sbjct: 374 QDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALS 433
Query: 439 ALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLE 498
T + + V+DINDN P Q SY YI ENN GA I ++ D D+ +NA++++ L+E
Sbjct: 434 TETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIE 493
Query: 499 QGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVT 558
+ + Y +IN D G++ +L DYE R+ +L D G P L++N+S+++F+
Sbjct: 494 DTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLL 553
Query: 559 DRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPN 615
D+NDNAP++LYP G + VE+ P G+LV++VV D D+G NAWLSY LL +
Sbjct: 554 DQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASE 613
Query: 616 QSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARA 675
LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + + A
Sbjct: 614 PGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILA 673
Query: 676 EFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSL 734
+ S + + +LT YL+++ VS F+ V ++ ++ +W +SR L +A L
Sbjct: 674 DLGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHKSR-LLQASGGGL 732
Query: 735 YRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCD 793
PG + D VR L + H+V LT DSR+S + +P A L S+++ +
Sbjct: 733 ASMPGSHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKKGF 790
Query: 794 PVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAM 853
+ +L + P QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAM
Sbjct: 791 LSAPQSLLEDKKEPFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAM 850
Query: 854 ILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKR 913
ILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKR
Sbjct: 851 ILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKR 910
Query: 914 DGKAPAGGNGNKKKSGKKEKK 934
DGKAPAGGNGNKKKSGKKEKK
Sbjct: 911 DGKAPAGGNGNKKKSGKKEKK 931
>gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 843 bits (2178), Expect = 0.0
Identities = 468/944 (49%), Positives = 600/944 (63%), Gaps = 23/944 (2%)
Query: 1 MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS 60
M + R GLV +V+ LL I Y IPEE K VGN+ +LGL +
Sbjct: 1 MKASSGRCGLVRWLQVLLPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRD 60
Query: 61 LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS 120
L AR+ RV A + +F VN E+G++ V+DR+DRE++CG P C + + V ENPL +F
Sbjct: 61 LPARKLRV--SAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFY 118
Query: 121 VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF 180
+ V++QDINDN P F ++ L+I E+ PGT FPL+ A D DVG NSLQ Y L+ NEYF
Sbjct: 119 IAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYF 178
Query: 181 ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN 240
L + D KY EL+L+ +LDRE QLVLTA+DGG P S + I IKV DANDN
Sbjct: 179 DLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDN 238
Query: 241 APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV 300
PVF+Q +YR + ED P G V+QV ATD DEG N EI YSF + + V+ F L+
Sbjct: 239 PPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQ-VKHFFNLNEK 297
Query: 301 TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP 360
TG +T K LDFE + + I+AKD G AHC + VE++D ND APE+ VTSV +P
Sbjct: 298 TGEITTKDDLDFEIASSYTLSIEAKDPG--DLAAHCSIQVEILDDNDCAPEVIVTSVSTP 355
Query: 361 VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV 420
+PED+P GTVIAL+ D D+GENG V C+V F L SS KNY+ L T LDRE +
Sbjct: 356 LPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEI 415
Query: 421 PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS 480
PEYNL+ITA D G P LS+ IV + +SD+NDN P Q+SY V++ ENN PGA I +S
Sbjct: 416 PEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQIS 475
Query: 481 VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS 540
DPD + ++S+ ++ + + Y +++ +G+V + D+E R FELT
Sbjct: 476 ASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQAR 535
Query: 541 DGGTPVLATNISVNIFVTDRNDNAPQVLYPR--PGGSSV-EMLPRGTSAGHLVSRVVGWD 597
D G+P L+ N+S+ + V D NDNAP+VLYP P GS++ +M+PR G+LV++VV D
Sbjct: 536 DQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVD 595
Query: 598 ADAGHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLS 657
AD+GHNAWLSY +L + LF++GL TG++ TAR + D D+ RQ L V ++D G+P LS
Sbjct: 596 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLS 655
Query: 658 TTATLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKV 717
TATL + + E + P + + L FYL+++L L+SV F + V I ++
Sbjct: 656 ATATLHLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVILAISLRL 715
Query: 718 YKWKQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPG 777
+S D + L PGP + + G L P+ Y+ + ++ L
Sbjct: 716 RLSSRS-DAWDCFQPGLSSKPGPGVLPNYSEGTL--PYSYNLCVASQSAKTEFNFLN--- 769
Query: 778 AASPLASRQNTLRSCDPVFYRQVL--GAESAPPG-----QQAPPNTDWRFSQAQRPGTSG 830
L Q+ + CD + Q GA P +QAPPNTDWRFSQAQRPGTSG
Sbjct: 770 ITPELVPAQDLV--CDNASWEQNTNHGAAGVPFASDTILKQAPPNTDWRFSQAQRPGTSG 827
Query: 831 SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV 890
SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV
Sbjct: 828 SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV 887
Query: 891 PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 888 PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 931
>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 829 bits (2141), Expect = 0.0
Identities = 452/928 (48%), Positives = 604/928 (65%), Gaps = 15/928 (1%)
Query: 15 RVVGVLLLLGALNKAST-VIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
++V + LL L +A I Y + EE ++G VGN+ +LGL+ +L+ + R+VS
Sbjct: 12 KLVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGR 71
Query: 74 RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
+ F +N +G + +R+DREELC C + +++E+ L ++SVEV I DINDN P
Sbjct: 72 SQLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAP 131
Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
F +E++L+ISE PG R PL++AHD DVG N+LQ Y L+ N++F+L V+ D KY
Sbjct: 132 RFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKY 191
Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
ELVLER+LDRE E LVL A DGG P LS + I +KVLDANDNAPVF Q YR +
Sbjct: 192 PELVLERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISI 251
Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
E+ GTR++ V ATD DEG +++Y F + ++F L +G LTI LD+E
Sbjct: 252 PENTLVGTRILTVTATDADEGYYAQVVY-FLEKSPGETSEVFELKSTSGELTIIKDLDYE 310
Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
D HEI I+A+D A KV+V V+DVNDNAPE +TS S V ED+ GT+I L
Sbjct: 311 DATFHEIDIEAQDGPGLLTRA--KVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGL 368
Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
+V D D+G+N TC +P LPF L S+ NY+ L T+ LDRE YN+++TA+D G
Sbjct: 369 FNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGG 428
Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
PSLS + +QV+DINDN P S++SY YI ENN GA + +++ DPD+ NA ++
Sbjct: 429 NPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488
Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
+ E + + Y +IN D G++ +L DYE R+ ++ D G P L++N+S+
Sbjct: 489 YSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSL 548
Query: 554 NIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
++FV D+NDNAP++LYP G + VE+ PR G+LV++VV D D+G NAWLSY L
Sbjct: 549 SLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHL 608
Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
L + LF++GLHTG++ TAR + D D+ +Q+L V I+D+G+P LS T TLTV+V +
Sbjct: 609 LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLTVAVADRI 668
Query: 671 PEARAEFPS---GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLY 727
P+ A+ S + P + +LT YL++++ VS F+ V ++ ++ +W +SR L
Sbjct: 669 PDILADLGSLEPSAIPNDS--DLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQ 726
Query: 728 RAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQN 787
+ S + D VR L + H+V LT DSR+S + +P A L S+++
Sbjct: 727 ASGGSLTGMQSSHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLISQES 784
Query: 788 TLRSCDPVFYRQVLGAESAPP-GQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD 846
+ + +L E QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD
Sbjct: 785 CEKKDFLSAPQSLLEEEREETFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD 844
Query: 847 TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL 906
TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL
Sbjct: 845 TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL 904
Query: 907 TNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
TNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 905 TNAAGKRDGKAPAGGNGNKKKSGKKEKK 932
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 828 bits (2138), Expect = 0.0
Identities = 452/934 (48%), Positives = 585/934 (62%), Gaps = 30/934 (3%)
Query: 19 VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFE 78
+L L L I Y +PEE ++G VGNV + LD SLSARR +V ++R F
Sbjct: 17 LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
Query: 79 VNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQ 138
V+ ++G + + + +DRE LCG SC V LE V E PLE++ EV I D+ND+ P FP Q
Sbjct: 77 VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
Query: 139 EMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVL 198
++ LEI EA PG RFPLE A D DVGSNS+ +Y LS NE+FAL V+ R D + EL+L
Sbjct: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
Query: 199 ERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAP 258
E+ LDRE++ +LVLTA+DGG P S + + + VLD NDNAP F QS YR VLE AP
Sbjct: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
Query: 259 SGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLH 318
+G ++Q+ A+D D GP+G + + F H VR LF+L TG LT+ G LDFE +
Sbjct: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
Query: 319 EIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTD 378
E ++A+D G+ HC + V+++DVNDNAP ITVTS +PE A GTV+AL+SV D
Sbjct: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
Query: 379 LDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLS 438
D+G NG V+ +P LPF+L S+ +N F+L T+ LDRE Y++ +TA DAG P LS
Sbjct: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
Query: 439 ALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLE 498
+ + +SD+NDNPP Q S++V++ ENN PG + +L+ DPD+ NA +S+ LLE
Sbjct: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
Query: 499 QGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVT 558
+ ++N G V + DYE + + D G P L++ ++V +FV
Sbjct: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
Query: 559 DRNDNAPQVLYP--RPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
D NDNAP VL P RPG + LP AGHL+++V D D+G+NAW+SY LL +P+
Sbjct: 557 DLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
Query: 617 SLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAE 676
SLFA+ + G++ TA P+ D P Q L +++KD+G P LST+ TL VS+ ED+ +
Sbjct: 617 SLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
Query: 677 FPSGSAPREQKKNLTFYLLLSLI---LVSVGFVVTVF---------GVIIFK----VYKW 720
SAPRE + LT YL +SL+ VS G V + GV F
Sbjct: 676 LRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLT 735
Query: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780
+ R P + + R S D ++ + H + L + RSD + ++
Sbjct: 736 RSRRREGLPPSNGILRIQLGS--DDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPSA 793
Query: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 840
P+A + SC P L +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
Sbjct: 794 PMAG-EPVRPSCPPSDLLYGL--------EQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 844
Query: 841 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 900
PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
Sbjct: 845 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 904
Query: 901 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 905 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
[Homo sapiens]
Length = 929
Score = 824 bits (2129), Expect = 0.0
Identities = 448/912 (49%), Positives = 591/912 (64%), Gaps = 25/912 (2%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y IPEE KG VGN+ +LGL + +SAR RV A + F V+ ++G++ V DR+
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRV--SAEKLHFSVDAQSGDLLVKDRI 90
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DRE++C C + LE VVENPL +F V VVI+D+ND+ P F E+ LEISE+V+ G
Sbjct: 91 DREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLGM 150
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
LESA DPD+ NSL Y+LS NEYF+L + D KY ELVL++ LDRE + + L
Sbjct: 151 GTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHL 210
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTALDGG P S + I I V+DANDN PVF+Q +YR + ED P GT +++V ATD D
Sbjct: 211 VLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQD 270
Query: 273 EGPNGEIIYSF-GSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANP 331
EG N EI YSF G ++A + +F+LD TG + + LDFE+ + + I I+AKD+G+
Sbjct: 271 EGINSEITYSFFGVADKA--QHVFSLDYTTGNILTQQPLDFEEVERYTINIEAKDRGSL- 327
Query: 332 EGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEV 391
CKV+VEVVD NDN+PEI +TS+ + ED+P G V+AL D D+GENG V C +
Sbjct: 328 -STRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCSL 386
Query: 392 PPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIN 451
G+PF + SS NY+ L T LDRE PEYN++I A D G P LS+ + + ++D+N
Sbjct: 387 SRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVN 446
Query: 452 DNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFT 511
DN P QS+Y V++ ENN PGA I +S DPD N R+S+ L+ E+ + Y +
Sbjct: 447 DNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVS 506
Query: 512 INRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPR 571
++ +G+V + D+E R FELT D G+P L+ N+S+ + V DRNDNAP+VLYP
Sbjct: 507 VSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPA 566
Query: 572 --PGGSSV-EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQI 628
P GS++ + +PR G+LV++VV DAD+GHNAWLSY ++ + LF++GL TG++
Sbjct: 567 LGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEV 626
Query: 629 STARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKK 688
R + D DS RQ L V ++D G+P LS TATL + + E +F P + +
Sbjct: 627 RMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQA 686
Query: 689 NLTFYLLLSLILVSVGFVVTVFGVIIFKVYK--WKQSRDLYRAPVSSLYRTPGPSLHADA 746
+ FYL+++L L+SV F++ V I ++ + + D + + + S GP +++
Sbjct: 687 EMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFESVLCSKSGPVGPPNYSEG 746
Query: 747 VRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVL----G 802
P+ Y+ + +P + + Q+ L D + +L
Sbjct: 747 T-----LPYAYN---FCVPGDQMNPEFNFFTSVDHCPATQDNLNK-DSMLLASILTPSVE 797
Query: 803 AESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAA 862
A+ QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAA
Sbjct: 798 ADKKILKQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAA 857
Query: 863 DGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGN 922
DGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGN
Sbjct: 858 DGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGN 917
Query: 923 GNKKKSGKKEKK 934
GNKKKSGKKEKK
Sbjct: 918 GNKKKSGKKEKK 929
>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
[Homo sapiens]
Length = 927
Score = 823 bits (2125), Expect = 0.0
Identities = 451/930 (48%), Positives = 595/930 (63%), Gaps = 40/930 (4%)
Query: 21 LLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVN 80
L GA+++ I Y IPEE G VG + +LGL + L R+ RV ++ +F V+
Sbjct: 22 LFCGAISQQ---IRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRV---SAEDYFNVS 75
Query: 81 RETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEM 140
E+G++ VN R+DRE++CG C + E V ENP+ +F V VVIQDINDN P F + +
Sbjct: 76 LESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGI 135
Query: 141 KLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLER 200
LEI E+ PG +F L+SA D DV NSL+ Y ++ N+YF+L + D +KY L+LE+
Sbjct: 136 DLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEK 195
Query: 201 ALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSG 260
LDRE + S +L+LTA+DGG P LS + I I+V DANDNAPVF+Q +YR + E+ P G
Sbjct: 196 PLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPWG 255
Query: 261 TRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEI 320
T V++V+ATD DEG N EI Y+F N LF L+ TG +T G LDFE+T + +
Sbjct: 256 TSVLRVMATDQDEGINAEITYAF--LNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVL 313
Query: 321 YIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLD 380
++AKD G + AHC V +E+VD NDNAPE+T S + +PED+ LGTVIAL+ V D D
Sbjct: 314 SVEAKDGGVHT--AHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKD 371
Query: 381 AGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSAL 440
+G+NG+VTC +PF L S+ KNY+ L + L+RE +YN++I A D G P+LS+
Sbjct: 372 SGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSR 431
Query: 441 TIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQG 500
T + + +SDINDN P Q+SY V++ ENN PGA I +S DPD N R+S+ +L
Sbjct: 432 TSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASD 491
Query: 501 AETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDR 560
E + Y +++ +G+V + D+E R FELT D G+P L+ N+S+ + V D
Sbjct: 492 LEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDL 551
Query: 561 NDNAPQVLYPR--PGGSSV-EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQS 617
NDNAP+VLYP P GS++ +M+PR G+LV++VV DAD+GHNAWLSY +L +
Sbjct: 552 NDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPG 611
Query: 618 LFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEF 677
LF++GL TG++ TAR + D D+ RQ L V ++D G+P LS TATL + + E +
Sbjct: 612 LFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDL 671
Query: 678 PSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRT 737
P + + L FYL+++L L+SV F++ V I ++ + S D + L
Sbjct: 672 SDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRR-SSSLDTEGCFQTGLCSK 730
Query: 738 PGPSLHADAVRGGLMSPHLYH-------------QVYLTTDSRRSDPLLKKPGAASPLAS 784
GP + + G L P+ Y+ + LT + LL + AS
Sbjct: 731 SGPGVPPNHSEGTL--PYSYNLCIASHSAKTEFNSLNLTPEMAPPQDLLCDDPSMVVCAS 788
Query: 785 RQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 844
++ + DP QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ
Sbjct: 789 NEDHKIAYDPSL-----------SSHQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 837
Query: 845 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 904
FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA
Sbjct: 838 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 897
Query: 905 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 898 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 927
>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 820 bits (2117), Expect = 0.0
Identities = 447/909 (49%), Positives = 588/909 (64%), Gaps = 25/909 (2%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y IPEE KG VGN+ +LG + L R+ RV S + +F V+ E+GE+ V+ RL
Sbjct: 33 IRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSS--EKPYFTVSAESGELLVSSRL 90
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREE+CG P+C + E V ENPL + V V I+DIND+ P F +L+ISE+ PGT
Sbjct: 91 DREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGT 150
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RF L SAHD D+GSN+LQ Y+LS +++F+L + + D +KY E+VL+ LDRE++ S L
Sbjct: 151 RFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHL 210
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
LTALD G P LS++ IH+ V DANDNAPVF+Q +YR + E+ GT V+QV ATD D
Sbjct: 211 TLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQD 270
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG N EI +SF + A F L+ TG +T+ LDFE+ K + I ++A+D G
Sbjct: 271 EGVNAEITFSF---SEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMI- 326
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
A C V VEV+D NDNAPE+ S+ + + EDA LGT IALL V D D+ NG VTC++
Sbjct: 327 -AQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKLE 385
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
+PF + +S +N + L T A LDRE PEYN+++TA D G P LS+ + + + + D+ND
Sbjct: 386 GDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVND 445
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
N P SQSSY V++ ENN PGA I + DPD N ++S+ ++ E + Y +I
Sbjct: 446 NAPVFSQSSYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSI 505
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPR- 571
+ ++G+V + D+E R FELT D G+P L+ N+S+ + V DRNDNAP+VLYP
Sbjct: 506 SAESGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPAL 565
Query: 572 -PGGSSV-EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
P GS++ +M+P G+LV++VV DAD+GHNAWLSY +L + LF++GL TG++
Sbjct: 566 GPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVR 625
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKN 689
TAR + D D+ RQ L V ++D G+P LS TATL + + E + P + +
Sbjct: 626 TARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSDLQAE 685
Query: 690 LTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADAVRG 749
L FYL+++L L+SV F+V + I ++ + +P S PG + +++V
Sbjct: 686 LQFYLVVALALISVLFLVAMILAIALRLRRSS-------SPASWSCFQPGLCVKSESVVP 738
Query: 750 GLMS----PHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAES 805
S P+ Y+ T + L + L+S Q+ L + +
Sbjct: 739 PNYSEGTLPYSYNLCVAHTGKTEFNFLK----CSEQLSSGQDILCGDSSGALFPLCNSSE 794
Query: 806 APPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGS 865
QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGS
Sbjct: 795 LTSHQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGS 854
Query: 866 STLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK 925
STLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK
Sbjct: 855 STLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK 914
Query: 926 KKSGKKEKK 934
KKSGKKEKK
Sbjct: 915 KKSGKKEKK 923
>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 814 bits (2102), Expect = 0.0
Identities = 445/907 (49%), Positives = 587/907 (64%), Gaps = 21/907 (2%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
I Y IPEE KG VGN+ +LG + L R+ RV S + +F V+ E+GE+ V+ RL
Sbjct: 33 IRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSS--EKPYFTVSAESGELLVSSRL 90
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DREE+CG P+C + E V ENPL + V V I+DIND+ P F +L+ISE+ PGT
Sbjct: 91 DREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGT 150
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RF LE A D D+G NSLQ Y+LS N F+L ++ ++D +KY EL LE+ LDRE++ +L
Sbjct: 151 RFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRL 210
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTALDGG P LS + + I+V DANDN PVFN+ +YR + E+ P GT V+QV ATD D
Sbjct: 211 VLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQD 270
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG N EI YSF R G Q+F+L+ +G +T + +LDFE+TK + + ++ +D G
Sbjct: 271 EGINSEITYSF---YRTG--QIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGGLV- 324
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
A C V + + D NDN+PE+T S+ + E+A GT+IAL+ + D D+GENG V C++
Sbjct: 325 -AQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQ 383
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
+PF + SS KN + L T LDRE PEYN++ITA D G P LS+ V + + D+ND
Sbjct: 384 GEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVND 443
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
N P Q+SY V + ENN PGA I + D D N ++S+ ++ E + Y ++
Sbjct: 444 NAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSM 503
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPR- 571
+ +G+V + DYE R FELT D G+P L+ N+S+ + V DRNDNAP+VLYP
Sbjct: 504 SAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPAL 563
Query: 572 -PGGSSV-EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQIS 629
P GS++ +M+PR G+LV++VV DAD+GHNAWLSY +L + LF++GL TG++
Sbjct: 564 GPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVR 623
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKN 689
TAR + D D+ RQ L V ++D G+P LS TATL + + E + P + +
Sbjct: 624 TARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSDPQAE 683
Query: 690 LTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADAVRG 749
L FYL+++L L+SV F++ V + ++ + S + L GP + + +G
Sbjct: 684 LQFYLVVALALISVLFLLAVILAVALRLRR-SSSPAAWSCFQPGLCVKSGPVVPPNYSQG 742
Query: 750 GLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTL--RSCDPVFYRQVLGAESAP 807
L P+ Y+ T + L + L+S Q+ L S +F ++
Sbjct: 743 TL--PYSYNLCVAHTGKTEFNFLK----CSEQLSSGQDILCGDSSGALFPLCNSSESTSH 796
Query: 808 PGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSST 867
P QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSST
Sbjct: 797 PELQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSST 856
Query: 868 LGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKK 927
LGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKK
Sbjct: 857 LGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKK 916
Query: 928 SGKKEKK 934
SGKKEKK
Sbjct: 917 SGKKEKK 923
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 812 bits (2097), Expect = 0.0
Identities = 438/932 (46%), Positives = 587/932 (62%), Gaps = 48/932 (5%)
Query: 33 IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92
+ Y + EE E G VGNV +LGL + L +RR ++ S + R+F ++ +G + VN ++
Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKI 90
Query: 93 DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152
DRE LCG SC + +++V E+PLEL VEV I D+NDN+P+F T E ++ ISE+ A G
Sbjct: 91 DRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASGA 150
Query: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212
RFPL+SA DPDVG+N++ Y LS N +F+L V+T +D + ELVLE+ LDRE + QL
Sbjct: 151 RFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQL 210
Query: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272
VLTA+DGGTPA S + I + VLD NDNAP F S+ R + E+AP GT ++++ ATD D
Sbjct: 211 VLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPD 270
Query: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332
EG NG++ YSFG H VR LF LD +G + + G +DFE+++ +EI+ +A+D+G
Sbjct: 271 EGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAM 330
Query: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392
HC + V+V DVNDNAPE+ + S+ +PV E P+GTV+ L +V D D+G NG V+ ++
Sbjct: 331 EGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDIS 390
Query: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452
P LPF + S +N+++L TS LDRE Y + + A DAG+PSL +R+ +SD+ND
Sbjct: 391 PDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVND 449
Query: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512
N P+ +Q Y YI EN PG+ + ++ DPD NARL++ ++ + + +
Sbjct: 450 NAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYV 509
Query: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPRP 572
N ++G + + DYE + ++ + D G+P L N S+++FV D NDNAP VL+PRP
Sbjct: 510 NPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRP 569
Query: 573 G--GSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL-GSPNQSLFAIGLHTGQIS 629
S+ + LPR G LV++V DADAGHNAWLSYSLL S LF + HTG++
Sbjct: 570 DWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVR 629
Query: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKN 689
TAR + + DS Q + VL++DNG+PSLS+TAT+ + + ++ PE + ++ +
Sbjct: 630 TARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIHPPERSD 689
Query: 690 LTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRD--------LYRAPVSSLYRTPGPS 741
LT YL+++L VS+ +VT F + K + D +P Y+ P+
Sbjct: 690 LTLYLIVALATVSLLSLVT-FTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDFYKQSSPN 748
Query: 742 LHADA----------VRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLA-------- 783
L + +R H Y + L+ P A
Sbjct: 749 LQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALALEPDAI 808
Query: 784 -SRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 842
SR NTLR QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
Sbjct: 809 RSRSNTLRE----------------RSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 852
Query: 843 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 902
NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
Sbjct: 853 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 912
Query: 903 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934
NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 913 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
[Homo sapiens]
Length = 930
Score = 803 bits (2074), Expect = 0.0
Identities = 441/913 (48%), Positives = 581/913 (63%), Gaps = 20/913 (2%)
Query: 30 STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVN 89
S I Y IPEE KG VGN+ +LGL + +SAR+ RV A + F V+ E+G++ V
Sbjct: 30 SEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRV--SAEKLHFSVDAESGDLLVK 87
Query: 90 DRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVA 149
+R+DRE++C C + LE VVENPL +F V VVI+D+ND+ P F +E+ LEI E+ +
Sbjct: 88 NRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKKEIHLEIFESAS 147
Query: 150 PGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPS 209
GTR L+ A DPD+ NS++ Y+++ N YF+L V+ D KY EL LE+ LDRE + S
Sbjct: 148 AGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRS 207
Query: 210 LQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLAT 269
L+LTALDGG P SA+ I I V D NDN PVF++ YR + E+ P G+ V+QV AT
Sbjct: 208 HSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRISLSENLPPGSPVLQVTAT 267
Query: 270 DLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGA 329
D DEG N EI Y F S ++ + +F+LD TGM+ DFED + + + ++AKD G
Sbjct: 268 DQDEGVNAEINYYFRSTAQS-TKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGG 326
Query: 330 NPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTC 389
CKV++E++D NDN+PEI +TS+ + E++P G V+AL DLD G NG V C
Sbjct: 327 L--STQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRC 384
Query: 390 EVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSD 449
+ +PF + SS NY+ L T LDRE PEYN++I A D G P LS+ + + V+D
Sbjct: 385 NIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVAD 444
Query: 450 INDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRY 509
INDN P Q+SY V++ ENN PGA I +S DPD N +S+ ++ E V Y
Sbjct: 445 INDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSY 504
Query: 510 FTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLY 569
+++ +G+V + D+E R F LT D G+P L+ N+S+ + V DRNDNAP+VLY
Sbjct: 505 VSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLY 564
Query: 570 PR--PGGSSV-EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTG 626
P P GS+ +M+PR G+LV++VV DAD+GHNAWLSY +L + LF++GL TG
Sbjct: 565 PALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTG 624
Query: 627 QISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQ 686
++ TAR + D D+ RQ L V ++D G+P LS TATL + ++ E + +
Sbjct: 625 EVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADNLQEILPDLSDRPVLSDP 684
Query: 687 KKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADA 746
+ L FYL+++L L+SV F++ V I ++ + S + L GP + +
Sbjct: 685 QAELQFYLVVALALISVLFLLAVILAIALRLRR-SLSPATWDCFHPGLCVKSGPVVPPNY 743
Query: 747 VRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESA 806
G L P+ Y+ T ++ + L + PL S ++ + S P G E
Sbjct: 744 SEGTL--PYSYNLCIAHTGTKEFNFLK----CSVPLHSNEDMVCSVSPGALIPPHGGEDL 797
Query: 807 PPG-----QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEA 861
QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEA
Sbjct: 798 TSHPETLTSQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEA 857
Query: 862 ADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGG 921
ADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGG
Sbjct: 858 ADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGG 917
Query: 922 NGNKKKSGKKEKK 934
NGNKKKSGKKEKK
Sbjct: 918 NGNKKKSGKKEKK 930
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 631 bits (1627), Expect = e-180
Identities = 377/943 (39%), Positives = 543/943 (57%), Gaps = 60/943 (6%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
LLLL A S +HY + EE + G VG + +LGL+L L R FRV S EV
Sbjct: 18 LLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ LE++V+ PL++F VEV ++DINDN P FP
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAV 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
L ISE+ PG+RF LE A D D+G+NSL TY L EYF L V+ ++ K LVL+
Sbjct: 138 KNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLK 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
+ L+RE P L++TA+DGG P L+ + + I VLD NDNAP F +++Y+ R+LE+AP+
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT VV V ATDLDEG N +I YSF + A + F LD V G +++KG +DFE++K +E
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I ++A DKG P HC VL+E+VD+NDN PE+ + S+ PV ED+PL TVIAL+SV+D
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
V V+V+D+NDN P SQS Y V+++ENN PG I +S D DA +NA +S+ L+E+
Sbjct: 438 TASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
NDNAP +L PR GG+ E++PR AGH+V++V DAD+G+NAWLSY L
Sbjct: 558 ENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGG 617
Query: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
+ F +GL+TG+IST R + + D+PR L VL+KD+GEPSL+ TAT+ VS+ E +P+
Sbjct: 618 ARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPV 731
A ++ +G + P ++ YL++++ VS V+T+ LY A
Sbjct: 678 ASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLL---------------LYTALR 722
Query: 732 SSLYRTPG------PSL-HADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLAS 784
S T G P+L + AV S +V ++D + P S
Sbjct: 723 CSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPIS 782
Query: 785 RQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT----- 839
R + + V SA P Q PN DWR+S + R G S + ++ G
Sbjct: 783 RDREEK-------QDVDVDLSAKPRQ---PNPDWRYSASLRAGMHSSVHLEEAGILRAGP 832
Query: 840 -WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYR 894
P+ Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 833 GGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELP 885
Query: 895 QNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 886 DKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 629 bits (1622), Expect = e-180
Identities = 356/803 (44%), Positives = 497/803 (61%), Gaps = 13/803 (1%)
Query: 15 RVVGVLLLLGALNKA-STVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGAS 73
R++ + LLLG L + + I Y + EE+E+G VGN+ +LGL L+ R R+VS
Sbjct: 12 RLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGR 71
Query: 74 RRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNP 133
+ F +N +G + R+DREELC P+C LE+++E+ +++ VEV I D+NDN P
Sbjct: 72 TQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPP 131
Query: 134 AFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKY 193
+F T++ +++++E PG RFPL A DPDVG NSLQ Y+L+ N YF+L VQ+ D KY
Sbjct: 132 SFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKY 191
Query: 194 AELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARV 253
ELVLERALDRE E LVLTA DGG P S + I I ++D NDNAPVF Q Y V
Sbjct: 192 PELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSV 251
Query: 254 LEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE 313
E+ P GTR++ V ATD DEG NG++ YSF R + QLF L+ ++G +TI G LD+E
Sbjct: 252 RENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITILGGLDYE 310
Query: 314 DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIAL 373
D+ ++I ++A D A KVLV V+D NDNAPE+TVTS+ S V E + GTVIAL
Sbjct: 311 DSGFYDIDVEAHD--GPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIAL 368
Query: 374 LSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAG 433
+V D D+G NGLVTC +P LPF+L + NY+ L T LDRE V EYN+++TA D G
Sbjct: 369 FNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQG 428
Query: 434 TPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLS 493
TP LS T + +QV DINDNPP +SY YI ENN GA IL+++ DPD+ NAR++
Sbjct: 429 TPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARIT 488
Query: 494 FFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISV 553
+ L E + + Y +IN + GI+ +L DYE R+ +L SD G P L++N+S+
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSL 548
Query: 554 NIFVTDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL 610
++FV D+NDN P++LY P G + VE+ PR +G+LV++VV D D+G NAWLSYSL
Sbjct: 549 SLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSL 608
Query: 611 LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS 670
L S LFA+GLHTG++ TAR + D D+ +Q L V+++D+G+P LS T TLTV+V +
Sbjct: 609 LKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSI 668
Query: 671 PEARAEFPSGSAPRE-QKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRA 729
P+ A+ S + LT YL++++ VS F+ V ++ K+ +W +SR L A
Sbjct: 669 PDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSR-LLHA 727
Query: 730 PVSSLYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNT 788
S L P + D VR L + H+V LT DSR+S + +P A L SR++
Sbjct: 728 EGSRLAGVPASHFVGVDGVRAFLQT--YSHEVSLTADSRKSHLIFSQPSYADTLISRESC 785
Query: 789 LRSCDPVFYRQVLGAESAPPGQQ 811
+S +P+ Q L P Q
Sbjct: 786 EKS-EPLLITQDLLETKGDPNLQ 807
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 627 bits (1616), Expect = e-179
Identities = 373/950 (39%), Positives = 544/950 (57%), Gaps = 47/950 (4%)
Query: 6 WRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARR 65
WR G + + R++ +LLLL A S +HY +PEE + G VG + +LGL+L L R
Sbjct: 5 WR-GELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
Query: 66 FRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVI 125
FRV S R EV+ + G +FVN R+DREELCG C++ LE++V+ PL++F V+V +
Sbjct: 64 FRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV 123
Query: 126 QDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQ 185
+D+NDN P F ++ KL +SE+ P +RFPLE A D DVG+NS+ TY LS ++YF L V
Sbjct: 124 KDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVN 183
Query: 186 TREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFN 245
++ D K ELVL ++LDRE P+ L LTA DGG P L+ ++ + + VLD NDNAP F
Sbjct: 184 SKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFE 243
Query: 246 QSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLT 305
QS Y R+ E+A +GT V+++ A+D DEG NG I YSF S V F++D TG +
Sbjct: 244 QSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIV 303
Query: 306 IKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDA 365
I+G LDFE L++I I A DKG P HC VLV ++D NDN PEI +TS+ PV EDA
Sbjct: 304 IRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDA 363
Query: 366 PLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNL 425
GTVIAL+SV DLD+G NG VTC + P +PF L S+ KNY++L + LDRE V Y L
Sbjct: 364 QFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYEL 423
Query: 426 SITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPD 485
+TARD G+PSL A + V+V+D+NDN P +Q Y V+++ENN PG I +S D D
Sbjct: 424 VVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
Query: 486 APQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTP 545
A +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G P
Sbjct: 484 AQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVP 543
Query: 546 VLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGH 602
L +N+++ +FV D NDNAP +L PR GG++ +++PR AGH+V++V DAD+G+
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGY 603
Query: 603 NAWLSYSL--LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660
NAWLSY L S + F +GL+TG+IST R + + DSPR L VL+KD+GEP+L+ TA
Sbjct: 604 NAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATA 663
Query: 661 TLTVSVTE--DSPEARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKV 717
T+ VS+ E +P+A + +G P ++ YL++++ VS V+T ++++
Sbjct: 664 TVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLT---LLLYTA 720
Query: 718 YKWKQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPG 777
+ P R P+L + G Q + + L+
Sbjct: 721 LRCS------ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSP 774
Query: 778 AASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDT 837
P L S D V Q L + +Q PN DWR+S + R G S + ++
Sbjct: 775 CLPP------DLGSVD-VGEEQDLNVDHGLKPRQ--PNPDWRYSASLRAGMHSSVHLEEA 825
Query: 838 GT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQ 888
G P+ Q+ T ++SA+ EA + S +G G + + +YGP Q
Sbjct: 826 GILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQ 878
Query: 889 HVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934
P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 879 SGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 626 bits (1614), Expect = e-179
Identities = 368/965 (38%), Positives = 551/965 (57%), Gaps = 58/965 (6%)
Query: 19 VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76
+LLLL A++ + Y +PEE+ G VGNV LGL+L L R+ + S R+
Sbjct: 30 LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
Query: 77 FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136
E++ +G +FVN+R+DRE LC P C ++LE++ NP+ + +VEV I DINDN+P FP
Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
Query: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196
+L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++ ++++K EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
Query: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256
VL + LDRE+ LVLTA+DGG PA S + I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
Query: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316
+P GT VV++ A+D DEG NGE+ YS S+ RQLF++D TG + + G LD+E+
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
Query: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376
++IY+QA D+G P HCKVLV++VDVNDNAPE+ +T +YSPVPE+A T++A+LSV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
Query: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436
D D+G N V+ + LPF L + N +TL S LDRE V YN+++TA D G P
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
Query: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496
L++L ++V++SDINDNPP + SY +YI+ENNLPG + + DPD +NA +++ L
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
Query: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556
LE+ + V Y +IN +G + ++ DYE REF +T D G+P L++ ++ N++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
Query: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
V D ND+AP +LYP SS EM+PR AG+LV++V+ D+D+G NAWL Y L +
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
+ LF + LHTG+I T R + D LTV+++DNGEPSLS + +TV+V + +
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
Query: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDL-------- 726
+ +T YL+++L VS F++T+ + I K Y++
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFCGV 748
Query: 727 -YRAPVSSLYRTPGPSLHADAVRGGLMSPHLY-------------HQVYLTTDSRRSDPL 772
R+P + LY+ ++ A G + PH ++ LT S +
Sbjct: 749 RERSP-AELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807
Query: 773 LKKPGA----------ASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQ 822
GA A+ SR T +S +L E+ + PN DWR+S
Sbjct: 808 FYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPDWRYSA 867
Query: 823 AQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAG 873
+ R G S + ++ G P+ Q+ T ++SA+ EA + S +G G
Sbjct: 868 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVN 920
Query: 874 TMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSG 929
+ + +YGP Q P + IPGS A ++ + K+ G K+++
Sbjct: 921 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 980
Query: 930 KKEKK 934
KK+KK
Sbjct: 981 KKKKK 985
>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
Length = 947
Score = 626 bits (1614), Expect = e-179
Identities = 367/957 (38%), Positives = 548/957 (57%), Gaps = 62/957 (6%)
Query: 5 AWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSAR 64
+W SG S R++ +LLLL A + +HY + EE + G VG + +LGL+L L R
Sbjct: 4 SWGSGQESR-RLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR 62
Query: 65 RFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVV 124
FRV S EVN + G +FVN R+DREELC C++ LE++V+ PL++F V+V
Sbjct: 63 LFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVE 122
Query: 125 IQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRV 184
++DINDN P FP + L I+E+ +RFPLE A D D+G N+L TY LS NEYF+L
Sbjct: 123 VRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEK 182
Query: 185 QTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVF 244
++ K L+L ++LDRE P + LVLTA DGG P L+ ++ + I VLDANDNAP F
Sbjct: 183 PPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAF 242
Query: 245 NQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGML 304
++++Y+ R+LE+ P+GT V+++ A+DLDEG NG+I+YSF + V+ F +D +TG +
Sbjct: 243 DRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQI 302
Query: 305 TIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPED 364
+KG +DFE++K +EI ++ DKG P HC+V+VEV D NDN P++ S+ P+ ED
Sbjct: 303 IVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIRED 362
Query: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYN 424
APLGTVIAL+SV+D D G NGLVTC + +PF L S+ KNY++L + LDRE+V Y
Sbjct: 363 APLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYE 422
Query: 425 LSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDP 484
L +TARD G+PSL A V V+V+D+NDN P +Q Y V+++ENN PG I +S WD
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482
Query: 485 DAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGT 544
DA +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGV 542
Query: 545 PVLATNISVNIFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAG 601
P L +N+++ +FV D NDNAP +L PR GG+ E++P GH+V++V DAD+G
Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSG 602
Query: 602 HNAWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTT 659
+NAWLSY L + F +GL+TG+IST R + +TD+PR L VL+KD+GEP+L+ T
Sbjct: 603 YNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTAT 662
Query: 660 ATLTVSVTE--DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFK 716
AT+ VS+ E +P+A + G+ P ++ YL++++ VS V+T+
Sbjct: 663 ATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLL------ 716
Query: 717 VYKWKQSRDLYRAPVSSLYRTPG------PSLHADAVRGGLMSPHLYHQVYLTTDSRRSD 770
LY A S T G P+L + G + +
Sbjct: 717 ---------LYTALRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKT 767
Query: 771 PLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSG 830
L+ + R++ L++ + F A P Q PN DWR+S + R G
Sbjct: 768 DLMAFSPSLPDSRDREDQLQTTEESF---------AKPRQ---PNPDWRYSASLRAGMHS 815
Query: 831 SQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARY 881
S + ++ G P+ Q+ T ++SA+ EA + S +G G + + +Y
Sbjct: 816 SVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKY 868
Query: 882 GPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934
GP Q P + IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 869 GPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 925
>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 622 bits (1604), Expect = e-178
Identities = 346/798 (43%), Positives = 491/798 (61%), Gaps = 13/798 (1%)
Query: 19 VLLLLGAL-NKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFF 77
+L LLG L A+ I Y IPEE EKG VGN+V +LGL+ L+ R+VS + F
Sbjct: 16 LLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLF 75
Query: 78 EVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPT 137
+N G + R+DREELC P C V+ ++VE+ L L+ VEV I DINDN P F
Sbjct: 76 SLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLK 135
Query: 138 QEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELV 197
+E++++I E AP +RFPL +DPDVG NSLQ ++LS N +F++ VQ+ KY ELV
Sbjct: 136 EELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELV 195
Query: 198 LERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDA 257
LE LDRE E +LVLTA+DGG P S+ I + VLD NDN P+F Q +YR V E+
Sbjct: 196 LEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENL 255
Query: 258 PSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKL 317
P GT V+ V ATD DEG +GE+ YSF + Q+F L+++TG ++ LD+ED+
Sbjct: 256 PVGTPVLAVTATDQDEGVHGEVTYSFVKITEK-ISQIFCLNVLTGEISTSANLDYEDSSF 314
Query: 318 HEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVT 377
+E+ ++A+D + A KVL+ ++DVNDN PE+ VTS + E AP GTVIAL V
Sbjct: 315 YELGVEARDGPGLRDRA--KVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVF 372
Query: 378 DLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSL 437
D D+G NGLVTC +P LPF L S+ NY+ L T+A LDRE V YN+++TA D GTP L
Sbjct: 373 DRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPL 432
Query: 438 SALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLL 497
S TI+ + V+D NDNPP SSY VY+ ENN GA I +++ DPD QNA++S+ L
Sbjct: 433 STETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLA 492
Query: 498 EQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFV 557
E + + Y +IN D GI+ +L DYE R+ +L SD G P L++N+S+++FV
Sbjct: 493 EDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFV 552
Query: 558 TDRNDNAPQVLY---PRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614
D+NDNAP++LY P G + VE+ PR G+LV++VV D D+G NAWLSY LL +
Sbjct: 553 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 612
Query: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674
LF++GLHTG++ TAR + D D+ +Q+L V ++D+G+P LS T TLTV+V + P+
Sbjct: 613 EPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDIL 672
Query: 675 AEFPS-GSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSS 733
A+ S + + +LT YL++++ VS F+ V ++ ++ +W +SR L +A
Sbjct: 673 ADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSR-LLQASGGG 731
Query: 734 LYRTPGPS-LHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSC 792
L PG + + VR L + H+V LT DSR+S + +P A L ++++ +S
Sbjct: 732 LASMPGSHFVGVEGVRAFLQT--YSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKS- 788
Query: 793 DPVFYRQVLGAESAPPGQ 810
+P+ Q L P Q
Sbjct: 789 EPLLITQDLLETKGEPRQ 806
>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
sapiens]
Length = 950
Score = 620 bits (1598), Expect = e-177
Identities = 367/936 (39%), Positives = 538/936 (57%), Gaps = 46/936 (4%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
LL+L S +HY +PEE E G VG + +LGL+L L R F++ S EV
Sbjct: 18 LLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ LE++V+ PL++F V+V ++DINDN P FP +
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQ 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
L I+E+ +RFPLE A D D+G N+L TY LS NEYF L V T K LVL
Sbjct: 138 KNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
+ LDRE P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY ++ E+
Sbjct: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT V+ A+DLDEG NG+IIYSF S ++ F +D ++G +T+ G +DFE+++ H+
Sbjct: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I ++A DKG P HC +LVEVVDVNDNAP++T+ ++ PV EDA LGTVIAL+SV DL
Sbjct: 318 IPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDL 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
DA NG VTC + P +PF L S+ KNY++L LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
V V+V+D+NDN P +QS Y V+++ENN PG I +S D DA +NA +S+ L+E+
Sbjct: 438 TARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616
NDNAP +L PR G+ EM+ R AG +V +V DAD+G+NAWLSY L
Sbjct: 558 ENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETAS 617
Query: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
+ F +GL+TG+IST R + +TD+PRQ L VL+KD+GEP+L+ TAT+ VS+ E +P+
Sbjct: 618 ASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPV 731
+ + G + P ++ YL++++ VS V+T ++++ V + P
Sbjct: 678 SSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLT---LLLYTVLRCS------AMPT 728
Query: 732 SSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS 791
P+L + G Q + + ++ L+ SP A +T R+
Sbjct: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAG--STERT 786
Query: 792 CDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQF 845
+P A S G+ PN DWR+S + R G S + ++ G P+ Q+
Sbjct: 787 GEP-------SASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQW 839
Query: 846 DTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPG 901
T ++SA+ EA + S +G G + + +YGP Q P + IPG
Sbjct: 840 PT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPG 892
Query: 902 SNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934
S A ++ + K+ G K+++ KK+KK
Sbjct: 893 SPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928
>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
Length = 948
Score = 620 bits (1598), Expect = e-177
Identities = 361/939 (38%), Positives = 551/939 (58%), Gaps = 54/939 (5%)
Query: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
LLLL A S + Y +PEE + G VG + +LGL+L L R FRV S EV
Sbjct: 18 LLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEV 77
Query: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
N + G +FVN R+DREELCG C++ +E++V+ PL++F VEV ++DINDN P FP
Sbjct: 78 NLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFPMTV 137
Query: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
+ E+ +RFPLE A D D+G N+L +Y+LS +E+F L +Q ++ ++ LVL
Sbjct: 138 KTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSLVLG 197
Query: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
++LDRE + L+L A DGG P L+ ++ I IKVLD NDN P F QS+Y+ ++LE+ +
Sbjct: 198 KSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTAN 257
Query: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
GT VV++ A+D DEGPN EI+YS GS + ++ F +D ++G + KG+LD+E+ K +E
Sbjct: 258 GTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYE 317
Query: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
I + A DKG HCK+ +++VD+NDN PE+++TS+ P+ E+A LGTVIAL++V+D
Sbjct: 318 IQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDR 377
Query: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A
Sbjct: 378 DSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437
Query: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
T V ++V+D+NDN P +Q Y V+++ENN PG I +S WD DA +NA +S+ L+E+
Sbjct: 438 TTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVER 497
Query: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
+ Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D
Sbjct: 498 RVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
Query: 560 RNDNAPQVLYPRPG---GSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL-LGSPN 615
NDNAP +L PR G G+ E++P AGH+V++V DAD+G+NAWLSY L LG+ +
Sbjct: 558 ENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGS 617
Query: 616 QSL-FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672
+ F +GL+TG+IST R + + DSPR L VL+KD+GEP+L+ TAT+ VS+ E +P+
Sbjct: 618 ARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
Query: 673 ARAEFPSGSAPREQK-KNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPV 731
A + G+A E ++ YL++++ VS V+T V+++ + P
Sbjct: 678 ASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLT---VLLYTALRCS-------VPP 727
Query: 732 SSLYRTPG-PSL-HADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPG-AASPLASRQNT 788
+ R PG P+L + AV S +V D ++D + P + P ++ +
Sbjct: 728 TEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQ 787
Query: 789 LRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPN 842
L +ES G+ PN DWR+S + R G S + ++ G P+
Sbjct: 788 L-------------SESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPD 834
Query: 843 NQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVY 898
Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 835 QQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFI 887
Query: 899 IPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 888 IPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 926
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,975,061
Number of Sequences: 37866
Number of extensions: 1767372
Number of successful extensions: 10620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 3736
Number of HSP's gapped (non-prelim): 728
length of query: 934
length of database: 18,247,518
effective HSP length: 112
effective length of query: 822
effective length of database: 14,006,526
effective search space: 11513364372
effective search space used: 11513364372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.