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Search of human proteins with 9966903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo
sapiens]
(630 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens] 1290 0.0
gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens] 661 0.0
gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens] 632 0.0
gi|218749883 alpha 1,2-mannosidase [Homo sapiens] 319 4e-87
gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 i... 190 3e-48
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [... 174 2e-43
gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 i... 166 5e-41
gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Ho... 157 2e-38
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 41 0.003
gi|169173182 PREDICTED: hypothetical protein [Homo sapiens] 40 0.008
gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo ... 38 0.032
gi|4885185 distal-less homeobox 3 [Homo sapiens] 37 0.042
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 37 0.055
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 36 0.094
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 36 0.094
gi|47132519 Ras association and pleckstrin homology domains 1 is... 36 0.094
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 36 0.094
gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens] 36 0.094
gi|68800230 zinc finger protein 197 isoform 2 [Homo sapiens] 36 0.094
gi|18860857 menin isoform 1 [Homo sapiens] 36 0.12
gi|18860855 menin isoform 1 [Homo sapiens] 36 0.12
gi|18860851 menin isoform 1 [Homo sapiens] 36 0.12
gi|18860849 menin isoform 1 [Homo sapiens] 36 0.12
gi|18860853 menin isoform 1 [Homo sapiens] 36 0.12
gi|18860839 menin isoform 1 [Homo sapiens] 36 0.12
gi|18860847 menin isoform 2 [Homo sapiens] 36 0.12
gi|24307909 ral guanine nucleotide dissociation stimulator isofo... 36 0.12
gi|108796058 ral guanine nucleotide dissociation stimulator isof... 36 0.12
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 36 0.12
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 36 0.12
>gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens]
Length = 630
Score = 1290 bits (3337), Expect = 0.0
Identities = 630/630 (100%), Positives = 630/630 (100%)
Query: 1 MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQ 60
MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQ
Sbjct: 1 MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQ 60
Query: 61 PGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREE 120
PGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREE
Sbjct: 61 PGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREE 120
Query: 121 ATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKE 180
ATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKE
Sbjct: 121 ATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKE 180
Query: 181 MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK 240
MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK
Sbjct: 181 MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK 240
Query: 241 AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTG 300
AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTG
Sbjct: 241 AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTG 300
Query: 301 IPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI 360
IPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI
Sbjct: 301 IPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI 360
Query: 361 EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA 420
EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA
Sbjct: 361 EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA 420
Query: 421 IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ 480
IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ
Sbjct: 421 IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ 480
Query: 481 ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI 540
ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI
Sbjct: 481 ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI 540
Query: 541 YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL 600
YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL
Sbjct: 541 YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL 600
Query: 601 LSLEDWVFNTEAHPLPVNHSDSSGRAWGRH 630
LSLEDWVFNTEAHPLPVNHSDSSGRAWGRH
Sbjct: 601 LSLEDWVFNTEAHPLPVNHSDSSGRAWGRH 630
>gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]
Length = 653
Score = 661 bits (1705), Expect = 0.0
Identities = 337/622 (54%), Positives = 438/622 (70%), Gaps = 20/622 (3%)
Query: 12 ASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFL---APRTQ-----QPGL 63
+ P LRL +KF+ LL S +TLCFGA+F LP SS+L L +P Q +PG
Sbjct: 31 SGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPGP 90
Query: 64 EVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATA 123
AE A AR +E AP P +D + + LR + T +
Sbjct: 91 GARAEDAAEGRARRRE---EGAPGDPEAALEDNLARIRENHERA-LREAKETLQKLPEEI 146
Query: 124 ARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEP-QSQVRAQREKIKEMM 182
R + + + + + F P +G ES+EP + +R +R KIKEMM
Sbjct: 147 QRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGV---ESREPADAAIREKRAKIKEMM 203
Query: 183 QFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAKAW 242
+ AW +YK YA G NEL+P++K G+ ++FG + GAT++D+LDTL++ME+K EF+EAK+W
Sbjct: 204 KHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAKSW 263
Query: 243 VGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIP 302
V E+ NV+ E S+FEVNIR++GGLLSA+YL+GEE+FR KA+ LG KLLPAF+TP+GIP
Sbjct: 264 VEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIP 323
Query: 303 KGVVSFKSG---NWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRK 359
+++ KSG NW WA+ GSS ILAEFG+LHLEF+HL+ LSGN +FAEKV NIR VL K
Sbjct: 324 WALLNMKSGIGRNWPWASGGSS-ILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNK 382
Query: 360 IEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALE 419
+EKP GLYPN+L+P SG W QHHVSVGGLGDSFYEYL+K+WLMS KTD+EAK MY++A++
Sbjct: 383 LEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQ 442
Query: 420 AIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAA 479
AIET+L+ S GLTYIAEW+GG+L+HKMGHL CF+GGM ALGA+ A E HY EL A
Sbjct: 443 AIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGA 502
Query: 480 QITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNP 539
+I +TCHESY R+ KLGPEAF F+ G EA+AT+ +E YYILRPEV+E+YMY+WR TH+P
Sbjct: 503 EIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDP 562
Query: 540 IYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDD 599
YR+W WE V ALE +CR G+SG++DVY ++D+ QQSFFLAETLKYLYL+FS+DD
Sbjct: 563 KYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDD 622
Query: 600 LLSLEDWVFNTEAHPLPVNHSD 621
LL LE W+FN+EAH LP+ D
Sbjct: 623 LLPLEHWIFNSEAHLLPILPKD 644
>gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]
Length = 641
Score = 632 bits (1631), Expect = 0.0
Identities = 324/619 (52%), Positives = 428/619 (69%), Gaps = 37/619 (5%)
Query: 17 LRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPR------------TQQPGLE 64
LRL +KF+ LL LS +TLCFGA F LP SS+ KR L + PG+
Sbjct: 31 LRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF 90
Query: 65 VVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAA 124
++ H E+E N A ++ A + RK R E+
Sbjct: 91 LIHGPDEHRHREEEERLRNKIRADHEKALEE----AKEKLRKSR-EEIRAEIQTEKNKVV 145
Query: 125 RGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQF 184
+ I ++P VP ++G R + ++ + +R +REKIKEMM+
Sbjct: 146 QEMKIKENKPLPP-VPIP------------NLVGIRGGDPED--NDIREKREKIKEMMKH 190
Query: 185 AWQSYKRYAMGKNELRPLTKDGYEGNMFGGLS-GATVIDSLDTLYLMELKEEFQEAKAWV 243
AW +Y+ Y G NELRP+ + G+ N+FG GAT++D+LDTLY+M L +EF + + W+
Sbjct: 191 AWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWI 250
Query: 244 GESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIPK 303
++ +V+ E S+FEVNIR+IGGLL+A+YL+GEE+F+IKA++L EKLLPAFNTPTGIP
Sbjct: 251 EDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPW 310
Query: 304 GVVSFKSG---NWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI 360
+V+ KSG NWGWA+AGSS ILAEFG+LH+EF+HL+ L+G+ + +KV +IRK+L+K+
Sbjct: 311 AMVNLKSGVGRNWGWASAGSS-ILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKM 369
Query: 361 EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA 420
++P GLYPN+L+P +G W Q+H SVGGLGDSFYEYL+K+WLMS KTD EA+ MY +A+EA
Sbjct: 370 DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEA 429
Query: 421 IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ 480
IE +L+ S GGLT+I EW+ G L+ KMGHLACF+GGM ALGA+ ++ +K HY EL A+
Sbjct: 430 IEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAE 489
Query: 481 ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI 540
I +TCHESY R+ KLGPE+F F+ EAVA + +E YYILRPEV+E+Y YLWR TH+P
Sbjct: 490 IARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPR 549
Query: 541 YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL 600
YR+WGWE LA+EKYCR GFSG++DVYSSTP HD+ QQSFFLAETLKYLYLLFS DDL
Sbjct: 550 YRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDL 609
Query: 601 LSLEDWVFNTEAHPLPVNH 619
L L+ WVFNTEAHPLPV H
Sbjct: 610 LPLDHWVFNTEAHPLPVLH 628
>gi|218749883 alpha 1,2-mannosidase [Homo sapiens]
Length = 699
Score = 319 bits (818), Expect = 4e-87
Identities = 223/631 (35%), Positives = 341/631 (54%), Gaps = 60/631 (9%)
Query: 26 LLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQPGLEVVAEIAGHAPAREQEPPPNPA 85
+LFL + C G LF + + K L +Q ++ EIAG PA PP PA
Sbjct: 86 ILFLLAFLLFC-GLLFYINLADHWKALAFRLEEEQ---KMRPEIAGLKPAN---PPVLPA 138
Query: 86 PAAPAPGEDDPSSWA--SPRRRKGGLRRTRP------------TGPREEATAARGNSIPA 131
P + DP + S ++ + ++R P G +EEAT + +
Sbjct: 139 PQK---ADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDGTQEEATKRQEAPVD- 194
Query: 132 SRPGDEGVPFRFDFNAFRSRLRHPVLGT-----RAD-ESQEPQSQVRAQ--------REK 177
P EG P R + +R + P GT RA+ ++ P R Q R+K
Sbjct: 195 --PRPEGDPQRTVIS-WRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQGTPVHLNYRQK 251
Query: 178 -IKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEF 236
+ ++ AW+ Y+++A G +EL+P+++ E FG G T+ID+LDT++++ L++EF
Sbjct: 252 GVIDVFLHAWKGYRKFAWGHDELKPVSRSFSE--WFG--LGLTLIDALDTMWILGLRKEF 307
Query: 237 QEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFN 296
+EA+ WV + H + +LFE IR +GGLLSA++L+G+ +F KA G +L+PAF
Sbjct: 308 EEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGNRLMPAFR 367
Query: 297 TPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKV 356
TP+ IP V+ +G S S +AE S+ LEF L+ L+G++ F E V + +
Sbjct: 368 TPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVEKVTQH 427
Query: 357 LRKIE-KPFGLYPNFLSPVSGNWVQHHV-SVGGLGDSFYEYLIKSWLMSGKTDMEAKNMY 414
+ + K GL P F++ SG + V ++G DS+YEYL+K W+ GK + + Y
Sbjct: 428 IHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQLLEDY 487
Query: 415 YEALEAIETYLLNVS-PGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAH 473
EA+E + T+LL S P LT++ E G KM HL CF G +ALG A
Sbjct: 488 VEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHGLP---AS 544
Query: 474 YRELAAQITKTCHESYARSDTKLGPEAFWFN----SGREAVATQLSESYYILRPEVVESY 529
+ ELA ++ +TC++ + +T L PE FN GR V + ++ + +LRPE VES
Sbjct: 545 HMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPETVESL 604
Query: 530 MYLWRQTHNPIYREWGWEVVLALEKYCRT-EAGFSGIQDVYS-STPNHDNKQQSFFLAET 587
YL+R T + Y++WGWE++ + ++ R G+S I +V P +K +SFFL ET
Sbjct: 605 FYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFFLGET 664
Query: 588 LKYLYLLFSED-DLLSLEDWVFNTEAHPLPV 617
LKYL+LLFS+D +LLSL+ +VFNTEAHPLP+
Sbjct: 665 LKYLFLLFSDDPNLLSLDAYVFNTEAHPLPI 695
>gi|222537737 ER degradation enhancer, mannosidase alpha-like 2
isoform 1 [Homo sapiens]
Length = 578
Score = 190 bits (483), Expect = 3e-48
Identities = 150/481 (31%), Positives = 225/481 (46%), Gaps = 76/481 (15%)
Query: 175 REKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKE 234
RE++K M A+ SY A +ELRPLT DG++ +G S T+ID+LDTL ++
Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGHD--TWGSFS-LTLIDALDTLLILGNVS 92
Query: 235 EFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKA--------IR 286
EFQ + +S ++ AS+FE NIR +GGLLSA L+ + ++A +R
Sbjct: 93 EFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLR 152
Query: 287 LGE----KLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSI--LAEFGSLHLEFLHLTEL 340
+ E KLLPAF TPTG+P G V+ G G + + A G+ +EF L+ L
Sbjct: 153 MAEEAARKLLPAFQTPTGMPYGTVNLLHG----VNPGETPVTCTAGIGTFIVEFATLSSL 208
Query: 341 SGNQVFAEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSW 400
+G+ VF + R L + GL N + ++G WV +G DS++EYL+K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGA 268
Query: 401 LMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIA 460
++ D + M+ E +AI Y T +W + +K G ++
Sbjct: 269 IL--LQDKKLMAMFLEYNKAIRNY---------TRFDDWYLWVQMYK---------GTVS 308
Query: 461 LGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESY-- 518
+ + E + L I T L W G + + Y
Sbjct: 309 MPVFQSLEAYWPGLQSLIGDIDNAMR-------TFLNYYTVWKQFGGLPEFYNIPQGYTV 361
Query: 519 -----YILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTP 573
Y LRPE++ES MYL+R T +P E G + V ++EK + E GF+ I+D+
Sbjct: 362 EKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDH-- 419
Query: 574 NHDNKQQSFFLAETLKYLYLLFSEDD-------------------LLSLEDWVFNTEAHP 614
DN+ +SFFLAET+KYLYLLF + +L ++FNTEAHP
Sbjct: 420 KLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHP 479
Query: 615 L 615
+
Sbjct: 480 I 480
>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
[Homo sapiens]
Length = 932
Score = 174 bits (441), Expect = 2e-43
Identities = 153/485 (31%), Positives = 237/485 (48%), Gaps = 61/485 (12%)
Query: 166 EPQSQVRAQR--EKIKEMMQFAWQSYKRYAMGKNELRPLTKDGY-------EGNMFGGLS 216
EP S+ Q+ ++ EM A+ +Y +A +EL PLT G G++ L
Sbjct: 42 EPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALG 101
Query: 217 --GATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYL 274
T+IDSLDTL ++ +EF++A V +L+ S+FE NIR +GGLL L
Sbjct: 102 KFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSL 161
Query: 275 T-------------GEEVFRIKAIRLGEKLLPAFNTPTGIPKGVVSFKSG-NWGWATAG- 319
+E+ ++ A +LG KLLPAFNT +G+P ++ K G A G
Sbjct: 162 AIMLKEKGEYMQWYNDELLQM-AKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGT 220
Query: 320 -SSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVL-RKIEKPFGLYPNFLSPVSGN 377
+ + A G+L LEF L+ +G +F E R L K ++ L ++ +G+
Sbjct: 221 ETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGD 280
Query: 378 WVQHHVSVGGLGDSFYEYLIKSWLMSGKTD-MEAKNMYYEALEAIETYLLNVSPGGLTYI 436
WV+ VG DS+YEYL+K++++ G +E N +Y+A+ + +S L
Sbjct: 281 WVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERFNTHYDAI------MRYISQPPLLLD 334
Query: 437 AEWRGGILDHK--MGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDT 494
+L+ + M L F G+ L D + H E+ Q+ K
Sbjct: 335 VHIHKPMLNARTWMDALLAFFPGLQVLKG-DIRPAIETH--EMLYQVIK---------KH 382
Query: 495 KLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEK 554
PEAF ++ + + LRPE ES +L++ T +P Y E G ++ L K
Sbjct: 383 NFLPEAF-------TTDFRVHWAQHPLRPEFAESTYFLYKATGDPYYLEVGKTLIENLNK 435
Query: 555 YCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFS--EDDLLSLEDWVFNTEA 612
Y R GF+ ++DV T +H+++ SFFLAE KYLYLLF+ ED + +ED++F TEA
Sbjct: 436 YARVPCGFAAMKDV--RTGSHEDRMDSFFLAEMFKYLYLLFADKEDIIFDIEDYIFTTEA 493
Query: 613 HPLPV 617
H LP+
Sbjct: 494 HLLPL 498
>gi|222537739 ER degradation enhancer, mannosidase alpha-like 2
isoform 2 [Homo sapiens]
Length = 541
Score = 166 bits (421), Expect = 5e-41
Identities = 132/437 (30%), Positives = 200/437 (45%), Gaps = 73/437 (16%)
Query: 219 TVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEE 278
T+ID+LDTL ++ EFQ + +S ++ AS+FE NIR +GGLLSA L+ +
Sbjct: 40 TLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKA 99
Query: 279 VFRIKA--------IRLGE----KLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSI--L 324
++A +R+ E KLLPAF TPTG+P G V+ G G + +
Sbjct: 100 GVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHG----VNPGETPVTCT 155
Query: 325 AEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVS 384
A G+ +EF L+ L+G+ VF + R L + GL N + ++G WV
Sbjct: 156 AGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAG 215
Query: 385 VGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGIL 444
+G DS++EYL+K ++ D + M+ E +AI Y T +W +
Sbjct: 216 IGAGVDSYFEYLVKGAIL--LQDKKLMAMFLEYNKAIRNY---------TRFDDWYLWVQ 264
Query: 445 DHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFN 504
+K G +++ + E + L I T L W
Sbjct: 265 MYK---------GTVSMPVFQSLEAYWPGLQSLIGDIDNAMR-------TFLNYYTVWKQ 308
Query: 505 SGREAVATQLSESY-------YILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCR 557
G + + Y Y LRPE++ES MYL+R T +P E G + V ++EK +
Sbjct: 309 FGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISK 368
Query: 558 TEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDD------------------ 599
E GF+ I+D+ DN+ +SFFLAET+KYLYLLF +
Sbjct: 369 VECGFATIKDLRDH--KLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGE 426
Query: 600 -LLSLEDWVFNTEAHPL 615
+L ++FNTEAHP+
Sbjct: 427 CILGAGGYIFNTEAHPI 443
>gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Homo
sapiens]
Length = 657
Score = 157 bits (398), Expect = 2e-38
Identities = 150/499 (30%), Positives = 232/499 (46%), Gaps = 86/499 (17%)
Query: 170 QVRAQ-REKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYE-----------GNMFGGLSG 217
Q+RAQ R+ + M F + +Y +A ++EL P+ G ++ G S
Sbjct: 125 QLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYS- 183
Query: 218 ATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYL--T 275
T++D+LDTL +M EFQ+A V + + +FE IR +G LLSA +
Sbjct: 184 LTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITD 243
Query: 276 GEEVFRIKAIR------------LGEKLLPAF-NTPTGIPKGVVSFKSG-----NWGWAT 317
++ F I+ L +LLPAF NT TGIP V+ K+G N T
Sbjct: 244 SKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCT 303
Query: 318 AGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI-EKPFGLYPNFLSPVSG 376
AG+ S+L EFG L+ L G+ F R K L + GL N ++ +G
Sbjct: 304 AGAGSLLVEFGI-------LSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTG 356
Query: 377 NWVQHHVSVGGLGDSFYEYLIKSWLMSG-KTDMEAKNMYYEALEAIETYLL--------- 426
+WV +G DSFYEYL+KS+++ G K D+E M+ A ++I+ YL
Sbjct: 357 HWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLE---MFNAAYQSIQNYLRRGREACNEG 413
Query: 427 NVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIAL--GAEDAKEEKRAHYRELAAQITKT 484
P + + G +++ + L F G+ L EDA
Sbjct: 414 EGDPPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDA----------------IC 457
Query: 485 CHESYARSDTKLG--PEAF-WFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIY 541
H Y + G PE + W + + +Y LRPE+VES L++ T NP Y
Sbjct: 458 LHAFYYAIWKRYGALPERYNWQLQAPDVL-------FYPLRPELVESTYLLYQATKNPFY 510
Query: 542 REWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDLL 601
G +++ +LEKY + + G++ + V + +++ +SFFL+ET KYLYLLF ED+ +
Sbjct: 511 LHVGMDILQSLEKYTKVKCGYATLHHVIDKST--EDRMESFFLSETCKYLYLLFDEDNPV 568
Query: 602 --SLEDWVFNTEAHPLPVN 618
S ++F TE H + V+
Sbjct: 569 HKSGTRYMFTTEGHIVSVD 587
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/117 (31%), Positives = 49/117 (41%), Gaps = 13/117 (11%)
Query: 56 PRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSS----WASPRRRKGGLRR 111
P+ +P +V +A +P + PPP PAPAA +PG P+S ASPR R
Sbjct: 740 PQVARP---LVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPR-----APR 791
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQ 168
T P G A A G ++PA R P + P TR S P+
Sbjct: 792 TSPYGGLPAAPLA-GPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPR 847
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/65 (32%), Positives = 22/65 (33%), Gaps = 3/65 (4%)
Query: 74 PAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIPASR 133
PA Q+ PP P P AP PG PR GPR R R
Sbjct: 28 PAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGR---LRSRDSSCGR 84
Query: 134 PGDEG 138
PG G
Sbjct: 85 PGTPG 89
>gi|169173182 PREDICTED: hypothetical protein [Homo sapiens]
Length = 255
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 14/82 (17%)
Query: 57 RTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRP-- 114
+T P LE+ A+ A + +P P PA P P P+ PR GG RT P
Sbjct: 124 QTTNPELELPADPA------QPDPAPLSRPAPPRPAHQSPAE-EGPRGAAGGGPRTPPAG 176
Query: 115 -----TGPREEATAARGNSIPA 131
+GPRE A+ G++ PA
Sbjct: 177 RTQGQSGPRESPRASPGSAAPA 198
>gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo
sapiens]
Length = 193
Score = 37.7 bits (86), Expect = 0.032
Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 26/115 (22%)
Query: 57 RTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTG 116
R+++PG E G R +PP P P P PG +GG RR
Sbjct: 86 RSRKPGPAARTEEGGDVTGRPWQPPLLPPPGVPTPG------------NRGGERRGERRA 133
Query: 117 PREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRA-DESQEPQSQ 170
P A A RG+ + A R P LG A D +P SQ
Sbjct: 134 PPRPAGAPRGSPMAAR-------------GRARGEAEPPALGAGACDSRNQPDSQ 175
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 37.4 bits (85), Expect = 0.042
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 43 LPHSSRLKRLFLAPRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASP 102
L HS P L + + APAR Q PPP P A+P+ +D +SW
Sbjct: 195 LEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHA 254
Query: 103 RRRKGGLRRTRPTGPREEATAARGNSIPASRPG 135
+ G + +P P AT + P PG
Sbjct: 255 QNLSGPHLQQQPPQP---ATLHHASPGPPPNPG 284
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 37.0 bits (84), Expect = 0.055
Identities = 30/105 (28%), Positives = 39/105 (37%), Gaps = 12/105 (11%)
Query: 49 LKRLFLAPRTQQPGLEVVAEIAGHAPAREQEP--PPNPAPAAPAPGEDDPSSWASPRRRK 106
L L L P Q + E H ARE P PP P P P P P P+ +
Sbjct: 1491 LSPLVLEPAASQDTIMATIEAVIHM-AREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPR 1549
Query: 107 GGLRRTRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSR 151
GG R+ +P P + P P + +P + A R R
Sbjct: 1550 GGKRKHKPQAPAQP---------PQQSPPQQPLPQEEEVKAKRQR 1585
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 36.2 bits (82), Expect = 0.094
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 15/89 (16%)
Query: 30 SGLVTLCFGALFLLPHSSRLKRL---------FLAPRTQQPGLEVVAEIAGHAPAREQEP 80
SGLVT C A FL+ S +L + LAP + P A PA Q+
Sbjct: 404 SGLVTSC-KAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKA 462
Query: 81 PPNPAP-----AAPAPGEDDPSSWASPRR 104
P PAP A PAP ++ ASPR+
Sbjct: 463 PAVPAPSQKAPAIPAPSRKASAASASPRK 491
Score = 29.6 bits (65), Expect = 8.8
Identities = 56/221 (25%), Positives = 82/221 (37%), Gaps = 39/221 (17%)
Query: 4 RKVPGFVPASPW----GLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQ 59
+K+P VPAS W GL PQK + + +P S+ AP +
Sbjct: 420 QKLPA-VPASSWKPPPGLAPPQK-------APAASAPPRKAPAVPAPSQKAPAVPAPSQK 471
Query: 60 QPGLEVVAEIAGHAPAREQEPPPNPAPA--APAPGEDDPSSWASPRR-------RKGGL- 109
P + + A A A ++ PAP P P + PS P++ +K L
Sbjct: 472 APAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLL 531
Query: 110 -----RRTRPTGPREEATAARGNSIPASR---PGDEGVPFRFDFNAFRSRLRHPVLGTRA 161
++ PT P E A S PASR PGD FD R + +++
Sbjct: 532 LPAPSQKALPTSPTEYQMAL---SPPASRGKLPGD------FDVLPTGIPGRAVLERSQS 582
Query: 162 DESQEPQSQVRAQREKIKEMMQFAWQSYKRYAMGKNELRPL 202
EP VR Q + EM A + + K E + +
Sbjct: 583 GGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDI 623
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 36.2 bits (82), Expect = 0.094
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 12/113 (10%)
Query: 62 GLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEA 121
GL++ +I R ++ P+PAPA PAP ++ P R+K R R +E A
Sbjct: 479 GLDLRRKILTQRRERYRQRSPSPAPA-PAPA----AAAGPPTRKKSRRERKRSGEAKEAA 533
Query: 122 TAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQ 174
+++ G ++P +D RSR R P G+ A S +S+ R++
Sbjct: 534 SSSSG-----TQPAPPAPASPWDSKKHRSRDRKP--GSHASSSARRRSRSRSR 579
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 36.2 bits (82), Expect = 0.094
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 11/95 (11%)
Query: 80 PPPNPAPAAPAPGEDDPSSWASPRRRKGG------LRRTRPTGPREEATAARGNSIPASR 133
PPP+P PA P P P ASP K G + + P G + T R +SI +S
Sbjct: 930 PPPSPVPAPPPP----PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985
Query: 134 PGDEGVPFRFDFNAFRSRLRHPV-LGTRADESQEP 167
+ P R ++ S+ P G+ + E+ P
Sbjct: 986 GAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 36.2 bits (82), Expect = 0.094
Identities = 24/68 (35%), Positives = 26/68 (38%), Gaps = 21/68 (30%)
Query: 71 GHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIP 130
G PA PPP APA PA D PS+ ASP G S P
Sbjct: 777 GPPPAPPPPPPPPRAPADPAASPDPPSAVASP---------------------GSGLSSP 815
Query: 131 ASRPGDEG 138
+PGD G
Sbjct: 816 GPKPGDSG 823
>gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens]
Length = 1029
Score = 36.2 bits (82), Expect = 0.094
Identities = 35/112 (31%), Positives = 48/112 (42%), Gaps = 19/112 (16%)
Query: 303 KGVVSFKSGNWGWATA--GSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI 360
+G+V K W W T+ GSSS + E LH L E SG Q E + +R++ R+
Sbjct: 14 EGLVKGKDDTWKWGTSFQGSSSSVWETSHLHFRQLRYHETSGPQ---EALSRLRELCRRW 70
Query: 361 EKPFG----------LYPNFLSPVSG---NWVQ-HHVSVGGLGDSFYEYLIK 398
+P + FLS + G WVQ HH G + E L K
Sbjct: 71 LRPEARTKAQILELLVLEQFLSILPGEIRTWVQLHHPGSGEEAVALVEELQK 122
>gi|68800230 zinc finger protein 197 isoform 2 [Homo sapiens]
Length = 267
Score = 36.2 bits (82), Expect = 0.094
Identities = 35/112 (31%), Positives = 48/112 (42%), Gaps = 19/112 (16%)
Query: 303 KGVVSFKSGNWGWATA--GSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI 360
+G+V K W W T+ GSSS + E LH L E SG Q E + +R++ R+
Sbjct: 14 EGLVKGKDDTWKWGTSFQGSSSSVWETSHLHFRQLRYHETSGPQ---EALSRLRELCRRW 70
Query: 361 EKPFG----------LYPNFLSPVSG---NWVQ-HHVSVGGLGDSFYEYLIK 398
+P + FLS + G WVQ HH G + E L K
Sbjct: 71 LRPEARTKAQILELLVLEQFLSILPGEIRTWVQLHHPGSGEEAVALVEELQK 122
>gi|18860857 menin isoform 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 469 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 528
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 529 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 585
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 586 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 614
>gi|18860855 menin isoform 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 469 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 528
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 529 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 585
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 586 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 614
>gi|18860851 menin isoform 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 469 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 528
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 529 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 585
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 586 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 614
>gi|18860849 menin isoform 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 469 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 528
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 529 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 585
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 586 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 614
>gi|18860853 menin isoform 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 469 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 528
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 529 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 585
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 586 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 614
>gi|18860839 menin isoform 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 469 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 528
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 529 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 585
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 586 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 614
>gi|18860847 menin isoform 2 [Homo sapiens]
Length = 610
Score = 35.8 bits (81), Expect = 0.12
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 11/149 (7%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGE---DDPSSWASPRRRKGGLRR 111
A ++P E E P RE +P P P PA + + + P R+ G
Sbjct: 464 AAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVA 523
Query: 112 TRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQ-----E 166
GP +TA PA+ P EG F + ++ ++ T+ + S
Sbjct: 524 GTARGPEGGSTAQ--VPAPAASPPPEGPVLTFQSEKMKG-MKELLVATKINSSAIKLQLT 580
Query: 167 PQSQVRAQREKIKEMMQFAWQSYKRYAMG 195
QSQV+ +++K+ + KR G
Sbjct: 581 AQSQVQMKKQKVSTPSDYTLSFLKRQRKG 609
>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
1 [Homo sapiens]
Length = 914
Score = 35.8 bits (81), Expect = 0.12
Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 9/69 (13%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPP--NPAPA-------APAPGEDDPSSWASPRRR 105
AP QQ V + APA E EP P +PAP+ APAP SW SP
Sbjct: 312 APELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWPSPVVA 371
Query: 106 KGGLRRTRP 114
+ GL +P
Sbjct: 372 ENGLSEEKP 380
>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
2 [Homo sapiens]
Length = 859
Score = 35.8 bits (81), Expect = 0.12
Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 9/69 (13%)
Query: 55 APRTQQPGLEVVAEIAGHAPAREQEPPP--NPAPA-------APAPGEDDPSSWASPRRR 105
AP QQ V + APA E EP P +PAP+ APAP SW SP
Sbjct: 257 APELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWPSPVVA 316
Query: 106 KGGLRRTRP 114
+ GL +P
Sbjct: 317 ENGLSEEKP 325
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 35.8 bits (81), Expect = 0.12
Identities = 17/36 (47%), Positives = 20/36 (55%)
Query: 73 APAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGG 108
+P R + PPP P PA P P PS A+P R GG
Sbjct: 90 SPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGG 125
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 35.8 bits (81), Expect = 0.12
Identities = 17/36 (47%), Positives = 20/36 (55%)
Query: 73 APAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGG 108
+P R + PPP P PA P P PS A+P R GG
Sbjct: 90 SPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGG 125
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,209,753
Number of Sequences: 37866
Number of extensions: 1345423
Number of successful extensions: 10061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 9153
Number of HSP's gapped (non-prelim): 952
length of query: 630
length of database: 18,247,518
effective HSP length: 108
effective length of query: 522
effective length of database: 14,157,990
effective search space: 7390470780
effective search space used: 7390470780
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.