Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 9945320

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9945320 cyclin L1 [Homo sapiens]
         (526 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9945320 cyclin L1 [Homo sapiens]                                  1053   0.0  
gi|88758580 cyclin L2 isoform A [Homo sapiens]                        583   e-166
gi|221554516 cyclin L2 isoform C [Homo sapiens]                       319   3e-87
gi|221554518 cyclin L2 isoform D [Homo sapiens]                       318   8e-87
gi|88758578 cyclin L2 isoform B [Homo sapiens]                        318   8e-87
gi|150417989 cyclin K isoform 1 [Homo sapiens]                        118   1e-26
gi|38176158 cyclin K isoform 2 [Homo sapiens]                         117   3e-26
gi|17978469 cyclin T2 isoform b [Homo sapiens]                        100   3e-21
gi|4502629 cyclin T2 isoform a [Homo sapiens]                         100   3e-21
gi|17978466 cyclin T1 [Homo sapiens]                                   97   4e-20
gi|196049382 family with sequence similarity 58, member A isofor...    97   4e-20
gi|196049384 family with sequence similarity 58, member A isofor...    94   2e-19
gi|157502165 family with sequence similarity 58 member B [Homo s...    81   2e-15
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          80   6e-15
gi|61676091 cyclin C isoform a [Homo sapiens]                          79   1e-14
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           78   2e-14
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     77   5e-14
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      75   1e-13
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    74   3e-13
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    74   4e-13
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           72   2e-12
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           72   2e-12
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    71   3e-12
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    70   5e-12
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap...    70   5e-12
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              69   8e-12
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso...    69   1e-11
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     69   1e-11
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H...    68   2e-11
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom...    68   2e-11

>gi|9945320 cyclin L1 [Homo sapiens]
          Length = 526

 Score = 1053 bits (2722), Expect = 0.0
 Identities = 526/526 (100%), Positives = 526/526 (100%)

Query: 1   MASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIP 60
           MASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIP
Sbjct: 1   MASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIP 60

Query: 61  EERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSF 120
           EERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSF
Sbjct: 61  EERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSF 120

Query: 121 VKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQ 180
           VKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQ
Sbjct: 121 VKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQ 180

Query: 181 VIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRF 240
           VIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRF
Sbjct: 181 VIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRF 240

Query: 241 QPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLE 300
           QPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLE
Sbjct: 241 QPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLE 300

Query: 301 KEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKT 360
           KEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKT
Sbjct: 301 KEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKT 360

Query: 361 VKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSG 420
           VKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSG
Sbjct: 361 VKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSG 420

Query: 421 TYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRD 480
           TYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRD
Sbjct: 421 TYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRD 480

Query: 481 HSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
           HSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR
Sbjct: 481 HSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526


>gi|88758580 cyclin L2 isoform A [Homo sapiens]
          Length = 520

 Score =  583 bits (1502), Expect = e-166
 Identities = 315/532 (59%), Positives = 392/532 (73%), Gaps = 23/532 (4%)

Query: 2   ASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPE 61
           A+   +  +AA AA++ AP +GG+ SG+         G+LIGDRLYS V +T+++ L+P+
Sbjct: 5   AAAAGAAGSAAPAAAAGAPGSGGAPSGSQ--------GVLIGDRLYSGVLITLENCLLPD 56

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           ++L  TPSM  GLD  +ETDLR++GCELIQAAGILLRLPQVAMATGQVLF RFFY+KSFV
Sbjct: 57  DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
           KHS E V+MAC++LASKIEEAPRRIRDVINVFH LRQLR K+ P PL+LDQ+Y+N KNQ+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176

Query: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQ 241
           IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQ LVQT+WNYMNDSLRT+VFVRFQ
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQ 236

Query: 242 PETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEK 301
           PE+IACACIYLAAR L+IPLP RPHWFLLFG TEEEIQEIC++ L+LY RKK +   LE 
Sbjct: 237 PESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEG 296

Query: 302 EVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASK-PSSPREVKAEEKSPISINVKT 360
           EVEKRK A++EAK +A+GL P GT  L    GFSPA K   SP+E K  + SP+S  VK 
Sbjct: 297 EVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLS--VKN 354

Query: 361 VKKEPEDRQQA-SKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRS 419
            K+  E  ++A + SP NG+ K   R   SRS SR +S +RS SRS +P+R  ++  S S
Sbjct: 355 TKRRLEGAKKAKADSPVNGLPKG--RESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTS 412

Query: 420 GTYSSRSRSRSRSHSESPRRHHNHGSPH----LKAKHTRDDLKSSNRHGHKRKKSRSRSQ 475
           G   S+S+SRSRS S+SP R     +P+    ++      D K   +    R +S SRS+
Sbjct: 413 G--GSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSR 470

Query: 476 SKSRDHSDAAKKHRHERGHHRD-RRERSRSFERSHKSKHHGGSRSGHGRHRR 526
           S+SR+ +D   K++ +  ++RD RRERSRS+ER+   + +     GH RHRR
Sbjct: 471 SRSRERADNPGKYKKKSHYYRDQRRERSRSYERT--GRRYERDHPGHSRHRR 520


>gi|221554516 cyclin L2 isoform C [Homo sapiens]
          Length = 236

 Score =  319 bits (818), Expect = 3e-87
 Identities = 160/231 (69%), Positives = 190/231 (82%), Gaps = 8/231 (3%)

Query: 2   ASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPE 61
           A+   +  +AA AA++ AP +GG+ SG+         G+LIGDRLYS V +T+++ L+P+
Sbjct: 5   AAAAGAAGSAAPAAAAGAPGSGGAPSGSQ--------GVLIGDRLYSGVLITLENCLLPD 56

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           ++L  TPSM  GLD  +ETDLR++GCELIQAAGILLRLPQVAMATGQVLF RFFY+KSFV
Sbjct: 57  DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
           KHS E V+MAC++LASKIEEAPRRIRDVINVFH LRQLR K+ P PL+LDQ+Y+N KNQ+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176

Query: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSL 232
           IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQ LVQT+W    D L
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWVASEDPL 227


>gi|221554518 cyclin L2 isoform D [Homo sapiens]
          Length = 227

 Score =  318 bits (815), Expect = 8e-87
 Identities = 158/224 (70%), Positives = 188/224 (83%), Gaps = 8/224 (3%)

Query: 2   ASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPE 61
           A+   +  +AA AA++ AP +GG+ SG+         G+LIGDRLYS V +T+++ L+P+
Sbjct: 5   AAAAGAAGSAAPAAAAGAPGSGGAPSGSQ--------GVLIGDRLYSGVLITLENCLLPD 56

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           ++L  TPSM  GLD  +ETDLR++GCELIQAAGILLRLPQVAMATGQVLF RFFY+KSFV
Sbjct: 57  DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
           KHS E V+MAC++LASKIEEAPRRIRDVINVFH LRQLR K+ P PL+LDQ+Y+N KNQ+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176

Query: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAW 225
           IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQ LVQT+W
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220


>gi|88758578 cyclin L2 isoform B [Homo sapiens]
          Length = 226

 Score =  318 bits (815), Expect = 8e-87
 Identities = 158/224 (70%), Positives = 188/224 (83%), Gaps = 8/224 (3%)

Query: 2   ASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPE 61
           A+   +  +AA AA++ AP +GG+ SG+         G+LIGDRLYS V +T+++ L+P+
Sbjct: 5   AAAAGAAGSAAPAAAAGAPGSGGAPSGSQ--------GVLIGDRLYSGVLITLENCLLPD 56

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           ++L  TPSM  GLD  +ETDLR++GCELIQAAGILLRLPQVAMATGQVLF RFFY+KSFV
Sbjct: 57  DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
           KHS E V+MAC++LASKIEEAPRRIRDVINVFH LRQLR K+ P PL+LDQ+Y+N KNQ+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176

Query: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAW 225
           IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQ LVQT+W
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score =  118 bits (296), Expect = 1e-26
 Identities = 93/360 (25%), Positives = 166/360 (46%), Gaps = 51/360 (14%)

Query: 48  SEVSLTIDHS----LIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVA 103
           S  S  +DH+       ++ L+ TPS  +GLD  +E   R  G   I   G  L L    
Sbjct: 11  SVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDT 70

Query: 104 MATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKR 163
           +ATG + FHRF+   SF +    +    C+ LA K+EE P++ +D+I     L       
Sbjct: 71  LATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLL------ 124

Query: 164 TPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QTLV 221
             + +   Q   + K +V+  ER +L+ + F + V+HP++ ++ Y + L+ ++N  Q LV
Sbjct: 125 --NDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLV 182

Query: 222 QTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPL------PTRPHWFLLF--GT 273
           Q AW ++NDSL T + ++++PE IA A +YLA R  +  +      P    W+  F    
Sbjct: 183 QMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDV 242

Query: 274 TEEEIQEICIETLRLYTRKK------------------PNYELLEKEVEKRKVALQEAKL 315
             + +++IC + L LY++ K                  P  ++ + +  +   + + ++ 
Sbjct: 243 PVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQP 302

Query: 316 KAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSP 375
           + K                 P+ +PSSPR+VK           + V   P++  +A++ P
Sbjct: 303 QQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVK-----------RAVVVSPKEENKAAEPP 351


>gi|38176158 cyclin K isoform 2 [Homo sapiens]
          Length = 354

 Score =  117 bits (292), Expect = 3e-26
 Identities = 79/260 (30%), Positives = 133/260 (51%), Gaps = 22/260 (8%)

Query: 48  SEVSLTIDHS----LIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVA 103
           S  S  +DH+       ++ L+ TPS  +GLD  +E   R  G   I   G  L L    
Sbjct: 11  SVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDT 70

Query: 104 MATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKR 163
           +ATG + FHRF+   SF +    +    C+ LA K+EE P++ +D+I     L       
Sbjct: 71  LATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLL------ 124

Query: 164 TPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QTLV 221
             + +   Q   + K +V+  ER +L+ + F + V+HP++ ++ Y + L+ ++N  Q LV
Sbjct: 125 --NDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLV 182

Query: 222 QTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPL------PTRPHWFLLF--GT 273
           Q AW ++NDSL T + ++++PE IA A +YLA R  +  +      P    W+  F    
Sbjct: 183 QMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDV 242

Query: 274 TEEEIQEICIETLRLYTRKK 293
             + +++IC + L LY++ K
Sbjct: 243 PVDVLEDICHQILDLYSQGK 262


>gi|17978469 cyclin T2 isoform b [Homo sapiens]
          Length = 730

 Score =  100 bits (250), Expect = 3e-21
 Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 18/243 (7%)

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           E+L  TPS + G++   E   R     LIQ  G  L + Q+ + T  V  HRF+   SF 
Sbjct: 16  EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQN---YINTK 178
           K +  I++   + LA+K+EE  R++  VI V H          P   +LD     Y+   
Sbjct: 76  KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129

Query: 179 NQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVF- 237
            +++  E  +L+ LGF + ++HPH  +V   Q++   ++  L QT++    +SL    F 
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187

Query: 238 VRFQPETIACACIYLAAR--ALQIPLPT-RPHWFLLFG--TTEEEIQEICIETLRLYTRK 292
           ++++P  IAC CI+LA +    +IP+ T   HW+       T E + E+  E L++   K
Sbjct: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQI-LEK 246

Query: 293 KPN 295
            PN
Sbjct: 247 TPN 249



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 53/225 (23%), Positives = 81/225 (36%), Gaps = 22/225 (9%)

Query: 291 RKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASK--PSSPREVKA 348
           R+K   E L+ +V    +A Q  +   +G +     A S+    SP     P +  E   
Sbjct: 440 REKRKLETLDLDVRDHYIAAQVEQQHKQGQSQ----AASSSSVTSPIKMKIPIANTEKYM 495

Query: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP 408
            +K   S ++K     P   + ASK       K S   R+S  +S   S     S  H  
Sbjct: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHS--SSDEGSGKSKHSSPHIS 553

Query: 409 RRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNH-GSPHLKAKHTRDDLKSSNRHG--- 464
           R H    +             SR H+ S +  H+H GS    +KH+ D +  +       
Sbjct: 554 RDHKEKHKEHPS---------SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604

Query: 465 -HKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERS 508
                 S S S S+ R H + A  + H +     +   S S   S
Sbjct: 605 LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 8/65 (12%)

Query: 457 LKSSNRHGHKRK---KSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKH 513
           + SS RH    +   KS+  S   SRDH +  K+H   R HH    + S S    H    
Sbjct: 529 VSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSR-HHTSSHKHSHS----HSGSS 583

Query: 514 HGGSR 518
            GGS+
Sbjct: 584 SGGSK 588


>gi|4502629 cyclin T2 isoform a [Homo sapiens]
          Length = 663

 Score =  100 bits (250), Expect = 3e-21
 Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 18/243 (7%)

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           E+L  TPS + G++   E   R     LIQ  G  L + Q+ + T  V  HRF+   SF 
Sbjct: 16  EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQN---YINTK 178
           K +  I++   + LA+K+EE  R++  VI V H          P   +LD     Y+   
Sbjct: 76  KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129

Query: 179 NQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVF- 237
            +++  E  +L+ LGF + ++HPH  +V   Q++   ++  L QT++    +SL    F 
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187

Query: 238 VRFQPETIACACIYLAAR--ALQIPLPT-RPHWFLLFG--TTEEEIQEICIETLRLYTRK 292
           ++++P  IAC CI+LA +    +IP+ T   HW+       T E + E+  E L++   K
Sbjct: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQI-LEK 246

Query: 293 KPN 295
            PN
Sbjct: 247 TPN 249



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 55/232 (23%), Positives = 84/232 (36%), Gaps = 28/232 (12%)

Query: 291 RKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASK--PSSPREVKA 348
           R+K   E L+ +V    +A Q  +   +G +     A S+    SP     P +  E   
Sbjct: 440 REKRKLETLDLDVRDHYIAAQVEQQHKQGQSQ----AASSSSVTSPIKMKIPIANTEKYM 495

Query: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP 408
            +K   S ++K     P   + ASK       K S   R+S  +S   S     S  H  
Sbjct: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHS--SSDEGSGKSKHSSPHIS 553

Query: 409 RRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNH-GSPHLKAKHTRDDLKSSNRHGHKR 467
           R H    +             SR H+ S +  H+H GS    +KH+ D +  +       
Sbjct: 554 RDHKEKHKEHPS---------SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604

Query: 468 KKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
             S   S S S   S   + H ++  H+   +        S  SK  GG R+
Sbjct: 605 LSSDGISSSSS---SSRKRLHVNDASHNHHSK-------MSKSSKSSGGLRT 646


>gi|17978466 cyclin T1 [Homo sapiens]
          Length = 726

 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 71/240 (29%), Positives = 119/240 (49%), Gaps = 12/240 (5%)

Query: 62  ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
           E+L  +PS + G+D   E   R     L+Q  G  L + Q+ + T  V  HRF+  +SF 
Sbjct: 17  EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76

Query: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
           +     VA A + LA+K+EE P+++  VI V H        +   P    + Y+     +
Sbjct: 77  QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133

Query: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVF-VRF 240
           +  E  +L+ LGF + + HPH  +V   Q++   ++  L QT++    +SL    F +++
Sbjct: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFSLQY 191

Query: 241 QPETIACACIYLAAR--ALQIPLPT-RPHW--FLLFGTTEEEIQEICIETLRLYTRKKPN 295
            P  +AC CI+LA +    +IP+ T   HW  ++    T E + E+  E L++   K PN
Sbjct: 192 TPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQI-LEKTPN 250



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 24/135 (17%), Positives = 50/135 (37%), Gaps = 5/135 (3%)

Query: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP 408
           +  S + + +     E  +R    K+    ++     +   ++AS      + R + H  
Sbjct: 430 DSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEIKMRIKVHAA 489

Query: 409 RRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHL-KAKHTRDDLKSSNRHGHKR 467
              +N+         ++SR     H   P  HH+H + H  K  H++  + + N+     
Sbjct: 490 ADKHNSVEDSV----TKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDP 545

Query: 468 KKSRSRSQSKSRDHS 482
           K S   S    + +S
Sbjct: 546 KHSSQTSNLAHKTYS 560


>gi|196049382 family with sequence similarity 58, member A isoform 1
           [Homo sapiens]
          Length = 248

 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 63/213 (29%), Positives = 108/213 (50%), Gaps = 16/213 (7%)

Query: 90  IQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDV 149
           I  AG+ L +  + +AT   ++H+FF   +   +   ++AM+ I LA K+EE   R RD+
Sbjct: 34  IMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDI 93

Query: 150 INVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYL 209
           INV +      G+    PL LD  +   ++ +++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 94  INVSNRYFNPSGE----PLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYL 149

Query: 210 QVLECERNQ------TLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPT 263
             L+   N+       +  TAW  + DS    + +RFQ + IA A +YLA +   + +P 
Sbjct: 150 VSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPA 209

Query: 264 RPH----WFLLFG--TTEEEIQEICIETLRLYT 290
                  W+ +F    T+  I  I  + +++YT
Sbjct: 210 EVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIYT 242


>gi|196049384 family with sequence similarity 58, member A isoform 2
           [Homo sapiens]
          Length = 228

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 60/197 (30%), Positives = 100/197 (50%), Gaps = 15/197 (7%)

Query: 90  IQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDV 149
           I  AG+ L +  + +AT   ++H+FF   +   +   ++AM+ I LA K+EE   R RD+
Sbjct: 34  IMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDI 93

Query: 150 INVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYL 209
           INV +      G+    PL LD  +   ++ +++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 94  INVSNRYFNPSGE----PLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYL 149

Query: 210 QVLECERNQ------TLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPT 263
             L+   N+       +  TAW  + DS    + +RFQ + IA A +YLA +   + +P 
Sbjct: 150 VSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPA 209

Query: 264 -----RPHWFLLFGTTE 275
                +P W +    TE
Sbjct: 210 EVEAEKPWWQIYTMDTE 226


>gi|157502165 family with sequence similarity 58 member B [Homo
           sapiens]
          Length = 252

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 16/213 (7%)

Query: 90  IQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDV 149
           I  AG+ L +  + +AT   ++ +FF           ++AM+ I LA K+EE P    D+
Sbjct: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97

Query: 150 INVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYL 209
           I+V +         +  PL LD      ++ +++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 98  ISVSNRYFN----PSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153

Query: 210 ----QVLECE--RNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPT 263
                 L C   +   +  TAW  + DS    + +RFQ + IA   +YLA +   + +P 
Sbjct: 154 VSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPA 213

Query: 264 RPH----WFLLFG--TTEEEIQEICIETLRLYT 290
                  W+  F    T+  I  I  + +++YT
Sbjct: 214 EVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIYT 246


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 70/191 (36%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 341 SSPREV--KAEEKSPISINVKTVKKEPE---DRQQASKSPYNGVRKDSKRSRN-SRSASR 394
           SSPR+   +++  SP      +  + P    DR + S+SPY    +   RS N +R  SR
Sbjct: 381 SSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSR-SRSPYKARDRSRSRSPNKARDCSR 439

Query: 395 SRS--RTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNH-GSPHLKAK 451
           SRS  + R RSRS +P +  ++ RSRS    +++R RSRS S S  R H+  GSP  +  
Sbjct: 440 SRSPYKARDRSRSRSPNKARDHSRSRS---PNKARDRSRSRSPSKERDHSQLGSPSKERD 496

Query: 452 HTRDDLKSSNRHGHKRKKSRSRSQSKSRDH--SDAAKKHRHERGHHRDRRERSRSFERS- 508
           H R     S     +R+  +SRS SK RDH  S +  K R  R      +ER RS  RS 
Sbjct: 497 HRR-----SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP 551

Query: 509 HKSKHHGGSRS 519
            + + H  SRS
Sbjct: 552 SEEREHRQSRS 562



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 65/214 (30%), Positives = 93/214 (43%), Gaps = 25/214 (11%)

Query: 333 GFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSA 392
           G S +  P+  R+  +  +SP     ++  + P   +  S+S      +D  RSR+   A
Sbjct: 388 GRSQSGSPNKQRD-HSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA 446

Query: 393 -SRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSE----SPRRHHNHGSPH 447
             RSRSR+ +++R H+  R  N  R RS    SRS S+ R HS+    S  R H      
Sbjct: 447 RDRSRSRSPNKARDHSRSRSPNKARDRS---RSRSPSKERDHSQLGSPSKERDHRRSRSP 503

Query: 448 LKAKHTRDDLKSSNRHGHKRKKS--------RSRSQSKSRDHSDA-----AKKHRHER-- 492
            K +  R    SS    H+R +S        +SRS +K RD S +      ++HR  R  
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563

Query: 493 GHHRDRRE-RSRSFERSHKSKHHGGSRSGHGRHR 525
              RDRR  RS S ER  +          H R R
Sbjct: 564 SKERDRRRWRSPSKERERRQSRSSSEERDHSRSR 597



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 64/204 (31%), Positives = 94/204 (46%), Gaps = 15/204 (7%)

Query: 317 AKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPY 376
           AK   P G P+       S    PSS R+VK+  +  I    K+    P +     KS Y
Sbjct: 217 AKCQTPTGIPSKEK----SDNPSPSSSRKVKSYGQMIIPSREKSYS--PTEMSSRVKS-Y 269

Query: 377 NGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSES 436
           N     S+   +S+S S  RSR+ S+ R+H+  R ++ +R+ S     R+RSR+R    S
Sbjct: 270 NQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS-----RARSRTRKGILS 324

Query: 437 PRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHR 496
               H+    H K K    +   + R G     SR+ S+ +S  HS ++ K R  RG   
Sbjct: 325 QMGRHSQSRSHSKGK--SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSS 382

Query: 497 DRRERSRSFERS-HKSKHHGGSRS 519
            R+E  RS   S +K + H  SRS
Sbjct: 383 PRKESGRSQSGSPNKQRDHSRSRS 406



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 67/235 (28%), Positives = 103/235 (43%), Gaps = 35/235 (14%)

Query: 316 KAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKS- 374
           K  G +  G+P  +     S +  P+  R+ ++  +SP     ++  + P   +  S+S 
Sbjct: 385 KESGRSQSGSP--NKQRDHSRSRSPNKARD-RSRSRSPYKARDRSRSRSPNKARDCSRSR 441

Query: 375 -PYNGVRKDSKRSRNS---------------RSASRSRSRTRSRSRSHTPRRHYNNRRSR 418
            PY    +   RS N                RS SRS S+ R  S+  +P +  ++RRSR
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501

Query: 419 SGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKS 478
           S    S+ R   +S S S  R H       K +  R   +S N+   +R +S+SRS S+ 
Sbjct: 502 S---PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS-RSPNK---ERDRSQSRSPSEE 554

Query: 479 RDH--SDAAKKHRHER-----GHHRDRRE-RSRSFERSHKSKHHGGSRSGHGRHR 525
           R+H  S +  K R  R        R+RR+ RS S ER H        +SG+ R R
Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 59/215 (27%), Positives = 89/215 (41%), Gaps = 20/215 (9%)

Query: 328 LSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKD----- 382
           LS +G  S  S+  S  + + + ++P         + P   +  S S  +   +D     
Sbjct: 323 LSQMGRHSQ-SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381

Query: 383 SKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHN 442
           S R  + RS S S ++ R  SRS +P +  +  RSRS     ++R RSRS S +  R  +
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS---PYKARDRSRSRSPNKARDCS 438

Query: 443 HGSPHLKAKHTRDDLKSSNRHGHKRK--------KSRSRSQSKSRDHS---DAAKKHRHE 491
                 KA+        +    H R         +SRSRS SK RDHS     +K+  H 
Sbjct: 439 RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498

Query: 492 RGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
           R     +  + R    S K + H  SRS     +R
Sbjct: 499 RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQR 533



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 61/232 (26%), Positives = 98/232 (42%), Gaps = 31/232 (13%)

Query: 311 QEAKLKAKGLNPDGTPAL---STLGGFSPASKPSSPREVKAEEKS--PISINVKTVKKEP 365
           Q   L  K   P G   +   S L      +K  +P  + ++EKS  P   + + VK   
Sbjct: 187 QPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYG 246

Query: 366 EDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSR 425
           +    + +  Y      S    +SR  S +++ TRSR +SH+  R  + RRSRSG   S+
Sbjct: 247 QMIIPSREKSY------SPTEMSSRVKSYNQASTRSRPQSHSQSR--SPRRSRSG---SQ 295

Query: 426 SRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRD----- 480
            R+ SR  S S +R+H+      +++  +  L    RH   R  S+ +SQ++SR      
Sbjct: 296 KRTHSRVRSHSWKRNHSRA----RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGR 351

Query: 481 ------HSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
                 +    + H H R   ++R  R  S  R    +   GS +    H R
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR 403



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 49/195 (25%), Positives = 84/195 (43%), Gaps = 18/195 (9%)

Query: 338 SKPSSPREVK--AEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSA--- 392
           S+  SP + +  +  +SP     ++  + P   +  S+       +D +RSR+       
Sbjct: 450 SRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC 509

Query: 393 --SRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKA 450
             SRS S+ R   RS +P +    R+SRS      ++ R RS S SP     H      +
Sbjct: 510 RQSRSSSKERDHRRSRSPSKERQRRQSRSP-----NKERDRSQSRSPSEEREHRQSRSPS 564

Query: 451 KHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHK 510
           K    D +       +R++ +SRS S+ RDHS +   ++ + G+    R R+ S E++H 
Sbjct: 565 KER--DRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK-QSGY---SRPRASSKEKAHS 618

Query: 511 SKHHGGSRSGHGRHR 525
                     H + R
Sbjct: 619 RSRTPSKEGNHSQSR 633



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 47/189 (24%), Positives = 84/189 (44%), Gaps = 26/189 (13%)

Query: 327 ALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDS--- 383
           +L+  G   P + P  P  +K+ + +  + N   V  +P   + +  SP +     S   
Sbjct: 13  SLAPSGSSMPTADPKPPASLKSTKSA--TPNRSLVPTKPATSRNSVMSPSSSKSTKSTST 70

Query: 384 KRSRNSRSASRSRSRTRSRSRSHT------------------PRRHYNNRRSRSGTYSSR 425
           KR+ ++R +SRSR R+++R+ S                     RR  ++R    G   SR
Sbjct: 71  KRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR 130

Query: 426 SRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAA 485
           S  RS S + +P R   HG+    A   R    +S + G  R KS  R ++ +R+ SD+ 
Sbjct: 131 SSKRSPSRASTPGRIRTHGARPGMASRVR--TPTSQQKG-SRGKSYGRPRTSNRERSDSQ 187

Query: 486 KKHRHERGH 494
            ++  ++ +
Sbjct: 188 PRNLSKKSY 196



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 23/186 (12%)

Query: 312 EAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQA 371
           +A+ +++  +P      S LG  SP SK    R  ++  K       ++  KE + R+  
Sbjct: 469 KARDRSRSRSPSKERDHSQLG--SP-SKERDHRRSRSPSKERQCRQSRSSSKERDHRR-- 523

Query: 372 SKSPYNGVRKDSKRSRNS---RSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYS----- 423
           S+SP    ++   RS N    RS SRS S  R   +S +P +  + RR RS +       
Sbjct: 524 SRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ 583

Query: 424 SRSRSRSRSH--SESPRRHHNHGSPHLKAK---HTRDDLKSSNRHGHKRKKSRSRSQSKS 478
           SRS S  R H  S SP +   +  P   +K   H+R   ++ ++ G+    S+SR+ SK 
Sbjct: 584 SRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS--RTPSKEGN---HSQSRTSSKE 638

Query: 479 RDHSDA 484
            D S +
Sbjct: 639 SDPSQS 644



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 15/150 (10%)

Query: 338 SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRK-----DSKRSRNSRSA 392
           SK    R+ ++  K       ++  +E E RQ  S S     R+       +  R SRS+
Sbjct: 528 SKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSS 587

Query: 393 SRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKH 452
           S  R  +RSRS    P +     R R+      S+ ++ S S +P +  NH      +K 
Sbjct: 588 SEERDHSRSRS----PNKQSGYSRPRAS-----SKEKAHSRSRTPSKEGNHSQSRTSSKE 638

Query: 453 TRDDLKSSNRHGHKRKKSRSRSQSKSRDHS 482
           + D  +S+       K+S +R+ S S++ +
Sbjct: 639 S-DPSQSTVPRSPDWKRSPTRTSSLSQNRT 667



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 30/132 (22%)

Query: 335 SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSAS- 393
           S +  PS  RE + + +SP     +   + P   ++  +S  +   +D  RSR+    S 
Sbjct: 546 SQSRSPSEEREHR-QSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604

Query: 394 ----RSRSRTRSRSRSHTPRRHYNNRRSRSGTYSS------------------------R 425
               R+ S+ ++ SRS TP +  N+ +SR+ +  S                        +
Sbjct: 605 YSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQ 664

Query: 426 SRSRSRSHSESP 437
           +R+ S++ S SP
Sbjct: 665 NRTPSKTSSHSP 676


>gi|61676091 cyclin C isoform a [Homo sapiens]
          Length = 283

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 17/216 (7%)

Query: 82  LRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEE 141
           L+I    +IQA G  L+L Q  +AT  V F RF+   S       ++A  C+ LASK+EE
Sbjct: 40  LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEE 99

Query: 142 APRRIRDVINVFHHLRQLRGK----RTPSPLILDQNYINTKNQVIKAERRVLKELGFCVH 197
                     V  + R +       +T       + +    N +++ E  +L+ +  C+ 
Sbjct: 100 --------FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLI 151

Query: 198 VKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARAL 257
           V HP++ ++ Y+Q  +  +   L+  AW  +ND+ RT++ + + P  IA AC+++A    
Sbjct: 152 VYHPYRPLLQYVQ--DMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQ 209

Query: 258 QIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKK 293
           Q        WF       E+I EI    L+LY + K
Sbjct: 210 Q---KDARQWFAELSVDMEKILEIIRVILKLYEQWK 242


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 76/205 (37%), Positives = 96/205 (46%), Gaps = 41/205 (20%)

Query: 336 PAS--KPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYN---------GVRKDSK 384
           PAS  K    +E + EE+       K    E ED   A  S YN           +K ++
Sbjct: 141 PASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNR 200

Query: 385 RSRN------SRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSR-SHSESP 437
           RSR+      SRS+SRS S + SRSRS +  R  ++ +SRS + SSR RSRSR S S S 
Sbjct: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS-SSRERSRSRGSKSRSS 259

Query: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRD 497
            R H   S   K  ++     SS+     RK+SRSRS S                G  + 
Sbjct: 260 SRSHRGSSSPRKRSYS----SSSSSPERNRKRSRSRSSSS---------------GDRKK 300

Query: 498 RRERSRSFERSHKS---KHHGGSRS 519
           RR RSRS ER H+S     H GSRS
Sbjct: 301 RRTRSRSPERRHRSSSGSSHSGSRS 325



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 38/196 (19%)

Query: 344 REVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRS 403
           ++ + +   P SI  +   KE E  ++      +  + D     +    S+         
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEE 191

Query: 404 RSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRH 463
            S+  +   +NRRSRS + SS SRS SRS S S                      SS   
Sbjct: 192 DSNKKK---SNRRSRSKSRSSHSRSSSRSSSPS----------------------SSRSR 226

Query: 464 GHKRKKSRSRSQSKS------RDHSDAAKKHRHERGHHRDRRERSRSF-------ERSHK 510
              R +S S SQS+S      R  S  +K     R H      R RS+       ER+ K
Sbjct: 227 SRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRK 286

Query: 511 SKHHGGSRSGHGRHRR 526
                 S SG  + RR
Sbjct: 287 RSRSRSSSSGDRKKRR 302



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 43/139 (30%), Positives = 66/139 (47%), Gaps = 8/139 (5%)

Query: 337 ASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNS-RSASRS 395
           ++K  S R  +++ +S  S +  +    P   +  S+S          RSR+S R  SRS
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRS-SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS 251

Query: 396 R-SRTRSRSRSH----TPR-RHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLK 449
           R S++RS SRSH    +PR R Y++  S       RSRSRS S  +  +R     SP  +
Sbjct: 252 RGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERR 311

Query: 450 AKHTRDDLKSSNRHGHKRK 468
            + +     S +R   K+K
Sbjct: 312 HRSSSGSSHSGSRSSSKKK 330



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 16/155 (10%)

Query: 293 KPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKS 352
           K N +  E+E   +K + + ++ K++  +   +         S +S PSS R        
Sbjct: 182 KYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSS---------SRSSSPSSSRSRSRSRSR 232

Query: 353 PISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHY 412
             S +    +    +R ++  S      K    SR+ R +S  R R+ S S S +P R+ 
Sbjct: 233 SSSSSQSRSRSSSRERSRSRGS------KSRSSSRSHRGSSSPRKRSYSSSSS-SPERNR 285

Query: 413 NNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPH 447
              RSRS +   R + R+RS S   R   + GS H
Sbjct: 286 KRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSH 320



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 5/97 (5%)

Query: 335 SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASR 394
           S +   SS RE      S    + ++ +     R+++  S  +   ++ KRSR+  S+S 
Sbjct: 237 SQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296

Query: 395 SRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSR 431
            R + R+RSRS   RRH    RS SG+  S SRS S+
Sbjct: 297 DRKKRRTRSRS-PERRH----RSSSGSSHSGSRSSSK 328


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 57/174 (32%), Positives = 87/174 (50%), Gaps = 13/174 (7%)

Query: 358 VKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSR-------SASRSRSRTRSRSRSHTPRR 410
           ++ V+ +P  R++ S S      +   RSR+SR       S+  S S++RSRSRS +  R
Sbjct: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229

Query: 411 HYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKS 470
             +  RS+S + S + +SRS S  +S  R H+ G    K+K   ++ K  N     + KS
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE-KIQNNDNVGKPKS 288

Query: 471 RSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERS-----HKSKHHGGSRS 519
           RS S+ KS+  S +  + R      R    R RS E+S      +S+  GGSRS
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 27/198 (13%)

Query: 335 SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNS----- 389
           S +   S  R V+ E++  +S   +   +E   RQ  S+S   G  +   RSR+      
Sbjct: 298 SKSRSRSQERRVEEEKRGSVS---RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354

Query: 390 ----RSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRS-----RSRSRSHSESPRRH 440
               RS   SRSR+RSRS+S   R+  + R S++G+   +      RS+SRS S S  + 
Sbjct: 355 KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKE 414

Query: 441 HNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSK------SRDHSDAAKKHRHERGH 494
             H       +  R + +++  +   R +SRS S+SK      SR  S +A K R  R  
Sbjct: 415 REHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTR-SRSK 473

Query: 495 HRDR---RERSRSFERSH 509
            R R   R  SRS  RSH
Sbjct: 474 SRSRSASRSPSRSRSRSH 491



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 60/212 (28%), Positives = 93/212 (43%), Gaps = 29/212 (13%)

Query: 339 KPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRN---SRSASRS 395
           K  SP   K++ KS      + V++E        +S    +R+   RSR+   SRS SRS
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346

Query: 396 RSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSR-------------------SRSHSES 436
           RS+++ + +     R  +  RSRS + S RSR R                    RS S S
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS 406

Query: 437 PRRHHNHGSPHLKAKHTRDDLK--SSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGH 494
           P R  +    H K++ ++ + +  S N   ++  +SRSRS SKS+ +  +  + R +   
Sbjct: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466

Query: 495 HRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
               R +SRS     +S     SRS    H R
Sbjct: 467 KTRSRSKSRS-----RSASRSPSRSRSRSHSR 493



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 52/156 (33%), Positives = 75/156 (48%), Gaps = 15/156 (9%)

Query: 381 KDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSS---------RSRSRSR 431
           +D   SR  RS SRSRS +RSRSRS    RH    RSRSG+  S         RS SRSR
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRS----RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229

Query: 432 SHSESPRRHHNHGSPHLKAKHTRDDLKS-SNRHGHKRKKSRSRSQSKSRDHSDAAK-KHR 489
           S S S  +  +          +++  +S S+  G  R KS+ +++ K +++ +  K K R
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289

Query: 490 HERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHR 525
               H    + RSRS ER  + +  G    G  + +
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 60/243 (24%), Positives = 103/243 (42%), Gaps = 21/243 (8%)

Query: 289 YTRKKPNYELLE-KEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVK 347
           Y+  K   E L+  EV  RK+ L E K         G+    +       S+  S     
Sbjct: 150 YSDMKRALEKLDGTEVNGRKIRLVEDK--------PGSRRRRSYSRSRSHSRSRSRSRHS 201

Query: 348 AEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHT 407
            + +S    +  +  K     +  S+S      +   RSR+ +  SRS S+ +SRSRSH+
Sbjct: 202 RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHS 261

Query: 408 PRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTR--DDLKSSNRHGH 465
             +  +  + ++      + +  +  S SP RH +      +++  R  ++ + S   G 
Sbjct: 262 AGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGR 321

Query: 466 KRKK----SRSRSQSK------SRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHG 515
            ++K    SRSRS+SK      SR  S +  K +  +    + R RSRS  +S +S+  G
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381

Query: 516 GSR 518
             R
Sbjct: 382 SKR 384



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 57/194 (29%), Positives = 85/194 (43%), Gaps = 12/194 (6%)

Query: 335 SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRN-SRSAS 393
           S   K  SP + K+  +S         K   + + QA +   N       +SR+ SR  S
Sbjct: 242 SKKEKSRSPSKEKSRSRSH-----SAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296

Query: 394 RSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSR-SRSRSRSHSESPRRHHNHGSPHLK--- 449
           +S+SR+RS+ R     +  +  R RS   S R SRSRSRS   S  R  +      K   
Sbjct: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356

Query: 450 AKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRR-ERSRSFERS 508
            K +R++ +S +R   K ++SR R   +      + KK + +    + R   RS S ER 
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKERE 416

Query: 509 HKSKHHGGSRSGHG 522
           H +K     R G G
Sbjct: 417 H-AKSESSQREGRG 429



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 54/204 (26%), Positives = 90/204 (44%), Gaps = 20/204 (9%)

Query: 290 TRKKPNYELLEKEVEKRKV-ALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKA 348
           ++ K      E+ VE+ K  ++   + + K L    + + S  G  S +   S  ++ + 
Sbjct: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355

Query: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSK----RSRNSRSASRSRSRTRSRS- 403
             K     + +  +     R ++ +S   G ++DSK    + +      RS+SR+ SRS 
Sbjct: 356 GRKR----SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411

Query: 404 -------RSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSES-PRRHHNHGSPHLKAKHTRD 455
                  +S + +R        +GT +  +RSRSRS+S+S P       S    A  TR 
Sbjct: 412 SKEREHAKSESSQREGRGESENAGT-NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470

Query: 456 DLKSSNRHGHKRKKSRSRSQSKSR 479
             KS +R    R  SRSRS+S SR
Sbjct: 471 RSKSRSRSA-SRSPSRSRSRSHSR 493



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 1/125 (0%)

Query: 313 AKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQAS 372
           ++ K++     G+   S  G      K  + R         +S   +  K E   R+   
Sbjct: 370 SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRG 429

Query: 373 KSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYS-SRSRSRSR 431
           +S   G  ++++    S S S+    + SRSRS +  +  +  +SRS + S S SRSRSR
Sbjct: 430 ESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489

Query: 432 SHSES 436
           SHS S
Sbjct: 490 SHSRS 494


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 60/170 (35%), Positives = 90/170 (52%), Gaps = 11/170 (6%)

Query: 357 NVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASR--SRSRTRSRSRSHTPRRHYNN 414
           N++ ++ +P    + S   Y+G R  S+  R SRS SR  SRSR+RS S+S +  R  + 
Sbjct: 175 NIRLIEDKPRTSHRRS---YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSK 231

Query: 415 RRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNR----HGHKRKKS 470
            RSRS +   +SRS+S+S  +S R  H+H     K ++ +   +S +R    +G    KS
Sbjct: 232 GRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKS 291

Query: 471 RSRSQSKSRDHSDAAKKHRHERG-HHRDRRERSRSFERSHKSKHHGGSRS 519
           +SRS+S+SR +S         R      +R  SRS  RS +SK    SRS
Sbjct: 292 KSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS-RSKSRSRSRS 340



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 50/151 (33%), Positives = 65/151 (43%), Gaps = 19/151 (12%)

Query: 335 SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASR 394
           S  S  S  R +        S +    +   + R+  SKS     +   K  R S S SR
Sbjct: 208 SRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS-----KSKPKSDRGSHSHSR 262

Query: 395 SRSR-----TRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLK 449
           SRS+     +RSRSRS +P+   N +        SRS+SRS S    P       SP  K
Sbjct: 263 SRSKDEYEKSRSRSRSRSPKE--NGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPK 320

Query: 450 AKHTRDDLKSSNRHGHKRKKSRSRSQSKSRD 480
              +R   +S       R KSRSRS+S SRD
Sbjct: 321 RATSRSRSRS-------RSKSRSRSRSSSRD 344



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 34/128 (26%), Positives = 54/128 (42%), Gaps = 18/128 (14%)

Query: 415 RRSRSGTYSSRSRSRS-------RSHSESPRRHHNHGSPHLKAKHTR---DDLKSSNRHG 464
           R++   TY+   + R+       RS+S+  R         +  ++ R   D  ++S+R  
Sbjct: 131 RQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRS 190

Query: 465 HK--------RKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGG 516
           +         R++SRSRS+  SR  S +  K R         R RSRS  R  +SK    
Sbjct: 191 YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSK 250

Query: 517 SRSGHGRH 524
            +S  G H
Sbjct: 251 PKSDRGSH 258


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 80/252 (31%), Positives = 110/252 (43%), Gaps = 27/252 (10%)

Query: 300  EKEV-EKRKVALQEAKLKA-KGLNPDGTPALSTLGGFS-------PASKPSSPR-EVKAE 349
            +KEV EK ++ L + K K  +G+     P  +T            P  KP   R E+K++
Sbjct: 1210 KKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSK 1269

Query: 350  EK----SPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRS 405
             K    S      KT +     R Q S S      +D      S S SRS+S T+SR R+
Sbjct: 1270 NKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRT 1329

Query: 406  HTPRRHYNNRRSRSGTYSSRSRSRSRSHSE---SPRRHHNHGSPHLKAKHTRDDLKSSNR 462
             +    ++  RSRS T S RSRS SRS S    S  R  +  S +   K  R   +S +R
Sbjct: 1330 RSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSR 1389

Query: 463  HGHKRKKSRSRS------QSKSRDHSDAAKKHRHERGHHRDRRERS-RSF---ERSHKSK 512
                   SRSRS       S+SR  S + +   + RG   +RR RS RS+     S +S 
Sbjct: 1390 SSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSY 1449

Query: 513  HHGGSRSGHGRH 524
             H  S S   R+
Sbjct: 1450 SHHRSPSESSRY 1461



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 55/188 (29%), Positives = 88/188 (46%), Gaps = 37/188 (19%)

Query: 362 KKEPEDRQQASKSPYNGVRKDSK---RSRNSRSASRSRSRTRSRS--------RSHTPRR 410
           +++  +  Q++ S Y+    +S    RSR+SRS S SRS TRSRS        RS + R 
Sbjct: 667 REKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRS 726

Query: 411 HYNNRR------SRSGTYSS-----------RSRSRSRSHSESPRRHHNHGSPHLKAKHT 453
           H  N+       SRS +Y+S           R RS  + +S S ++H +     L +K+ 
Sbjct: 727 HSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKY- 785

Query: 454 RDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSH--KS 511
              +K  +R    RK S SRS   S D+S  +++   +       +E+    ER+H  + 
Sbjct: 786 ---VKGRDRSSCVRKYSESRS---SLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQE 839

Query: 512 KHHGGSRS 519
           K+ G  +S
Sbjct: 840 KNRGEEKS 847



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 45/200 (22%)

Query: 335  SPASKPSSPREVKA----EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSR 390
            +P +  SS  EVK      E  P  + ++   K     +    S ++ VRK ++ +R  R
Sbjct: 1237 APNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKN----KVRPGSLFDEVRKTARLNRRPR 1292

Query: 391  SASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKA 450
            +   S       S   TP        SR     SRS SRSRS SE+  RH          
Sbjct: 1293 NQESS-------SDEQTP--------SRDDDSQSRSPSRSRSKSETKSRHRTR------- 1330

Query: 451  KHTRDDLKSSNRHGHKRKKSRSRSQS-KSRDHSDAAKKHRHERGHHRDRRERSRSFERSH 509
                     S  + H R +SRS + S +SR +S +  +  + RG  R R    RS+ +SH
Sbjct: 1331 ---------SVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSY-KSH 1380

Query: 510  KSKHHGGSRSG----HGRHR 525
            ++     SRS     H R R
Sbjct: 1381 RTSSRSRSRSSSYDPHSRSR 1400



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 48/185 (25%), Positives = 74/185 (40%), Gaps = 41/185 (22%)

Query: 339 KPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSR 398
           KPS  R  + + K+   + +++       ++  S S Y+      KR +NS S   + S+
Sbjct: 627 KPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYH------KREKNSESDQSTYSK 680

Query: 399 TRSRSRSHTPRRHYNNRRSRSGTYS-SRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDL 457
              RS   +PR    + RSRS + S +RSRS + SHS S                     
Sbjct: 681 YSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRS--------------------- 719

Query: 458 KSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRH-----ERGHHRDRRERSRSFERSHKSK 512
                   +   SRS S++K  DHS  ++   +     + G    RR RS   + S   K
Sbjct: 720 --------RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHK 771

Query: 513 HHGGS 517
            H  S
Sbjct: 772 KHSSS 776



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 21/152 (13%)

Query: 347 KAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSH 406
           K  ++  +    K  K++   R + +K     +  D + S++S    +S       SRS 
Sbjct: 429 KRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSS 488

Query: 407 TPRRHYNNRR---------SRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDL 457
           +   H++++R           S T+SSR   RS+SHS+S    ++ GS       +R   
Sbjct: 489 SLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQS----YSRGS-----SRSRTAS 539

Query: 458 KSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR 489
           KSS+   H R +S+SRS SKS     A+K  R
Sbjct: 540 KSSS---HSRSRSKSRSSSKSGHRKRASKSPR 568



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 15/162 (9%)

Query: 369 QQASKSPYNGVRKDSKRSRNS------RSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTY 422
           Q++    YNG   D   +R+S      R   + + + + + + H  RRH   ++ R    
Sbjct: 404 QRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHC-RRHKQTKKRRILIP 462

Query: 423 SS--RSRSRSRSHSESPRRHHNHGSPHLKAKHT-RDDLKSSNRHGHKRKKSRSRSQSKSR 479
           S    S+S +R    S  R  +  S  L + H+ + D   S++         SR   +S+
Sbjct: 463 SDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSK 522

Query: 480 DHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGH 521
            HS +     + RG  R R     S     +SK    S+SGH
Sbjct: 523 SHSQS-----YSRGSSRSRTASKSSSHSRSRSKSRSSSKSGH 559



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 48/167 (28%), Positives = 67/167 (40%), Gaps = 48/167 (28%)

Query: 335  SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASR 394
            S + + +  R+  ++ +SP     K+  K     +  S S      + S  S  SRS SR
Sbjct: 1296 SSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSR 1355

Query: 395  SRSR-------TRSRS---RSHTPRRHYNNRRSRSGTYS--------------SRSRSRS 430
            SRSR       TRSRS   RS+   R  +  RSRS +Y               SRSRSRS
Sbjct: 1356 SRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRS 1415

Query: 431  RSH------------------------SESPRRHHNHGSPHLKAKHT 453
            RS                         SES R + +H SP   ++++
Sbjct: 1416 RSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 4/117 (3%)

Query: 343 PREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSR 402
           P ++++ + S   +   +  +E   R  +  S ++  R  SK  ++ +S+    SR   R
Sbjct: 462 PSDIESSKSSTRRMK-SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYR 520

Query: 403 SRSHTPRRHYNNRRSRSGTYS---SRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDD 456
           S+SH+      + RSR+ + S   SRSRS+SRS S+S  R     SP   A    ++
Sbjct: 521 SKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSEN 577



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 23/135 (17%)

Query: 370 QASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSR 429
           ++SKS    ++    R R+SRS+S S   +  R  S + +   +     S T+SSR   R
Sbjct: 466 ESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQS-----SLTHSSRDSYR 520

Query: 430 SRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR 489
           S+SHS+S    ++ GS       +R   KSS         S SRS+SKSR  S +  + R
Sbjct: 521 SKSHSQS----YSRGS-----SRSRTASKSS---------SHSRSRSKSRSSSKSGHRKR 562

Query: 490 HERGHHRDRRERSRS 504
             +   +   + S +
Sbjct: 563 ASKSPRKTASQLSEN 577



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 5/105 (4%)

Query: 338 SKPSSPREVKAE---EKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASR 394
           S  SS R +K+    E+S  S ++ +      D  ++ K   + +   S+ S   RS S 
Sbjct: 467 SSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSY--RSKSH 524

Query: 395 SRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRR 439
           S+S +R  SRS T  +  ++ RSRS + SS      +  S+SPR+
Sbjct: 525 SQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRK 569



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 62/260 (23%), Positives = 100/260 (38%), Gaps = 18/260 (6%)

Query: 273 TTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAK-GLNPDGTPALSTL 331
           ++ E   E  +E  R   RK      +++  ++RK A    + + K  +NP G    S  
Sbjct: 206 SSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDT 265

Query: 332 G---GFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRN 388
                   ++K   P  V+ EE  P+  N   ++++        +     V       + 
Sbjct: 266 NEKRSVDSSAKREKP-VVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKP 324

Query: 389 SRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHL 448
           S S S  + + R   R HTP R     RS S +    S        E  +R   +  P  
Sbjct: 325 SVSKSGRKIKGRGTIRYHTPPRS----RSCSESDDDDSSETPPHWKEEMQRLRAYRPPSG 380

Query: 449 KAKHTRDDLKS--SNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFE 506
           +     D L    S+R   +    RSRS S +  +SD +   RH  GHH+ RR+     E
Sbjct: 381 EKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTA-RHS-GHHKKRRK-----E 433

Query: 507 RSHKSKHHGGSRSGHGRHRR 526
           +  K K  G  +    RH++
Sbjct: 434 KKVKHKKKGKKQKHCRRHKQ 453



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 8/100 (8%)

Query: 421 TYSSRSRSRSRSHSESPRRHHNHGSPHLK-AKHTRDDLKSSNRHGHKRKKSRSRSQSKSR 479
           TYS  +   + S S   +R  N  S     +K++    +SS R   +  +SRS S+S +R
Sbjct: 649 TYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTR 708

Query: 480 DHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
             S A+        H R R   SRS  R+  S H   SRS
Sbjct: 709 SRSLASS-------HSRSRSPSSRSHSRNKYSDHSQCSRS 741



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 37/191 (19%), Positives = 75/191 (39%), Gaps = 11/191 (5%)

Query: 335 SPASKPSSPREVKAEEKSPISINVKTV-KKEPEDRQQASKSPYNGVRKDSKRSRNSRSAS 393
           S  S+ SS   + +++       +++  KK     ++ S S    +     + R+  S  
Sbjct: 736 SQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCV 795

Query: 394 RSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGS------PH 447
           R  S +RS     +     + + ++S     +     R+H++  +      S      PH
Sbjct: 796 RKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPH 855

Query: 448 LKAKHTRDDLKSSNRHGHKRKKSR---SRSQSKSRDHSDAAKKHRHERGHHRDRRE-RSR 503
            K +  +++L    R+G K K+     S+  S+S    D  K  +++     D+ E  + 
Sbjct: 856 SKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEAT 915

Query: 504 SFERSHKSKHH 514
           S   S  S+ H
Sbjct: 916 SDSESEVSEIH 926



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 4/99 (4%)

Query: 354 ISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRT---RSRSRSHTPRR 410
           I   V   K   +  ++  K P +    DS  + +S S S S S     RSR R H  R 
Sbjct: 171 IDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRP 230

Query: 411 HYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLK 449
                + R    SS    R++ H+ +P+ H      + K
Sbjct: 231 KVKRSKKRRKEASSSEEPRNK-HAMNPKGHSERSDTNEK 268



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 6/119 (5%)

Query: 359  KTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRH--YNNRR 416
            + V K  ++    S     G       S  S    + +  T+S + +  P  +  + + +
Sbjct: 893  RDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSK 952

Query: 417  SRSGTYSSR-SRSRSRSHSESPRRHHNHGSPHLKAKHT---RDDLKSSNRHGHKRKKSR 471
             R+ T  S  S S S ++   P++H +    +LK +HT   ++ LK      HK  K +
Sbjct: 953  QRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRK 1011



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 8/91 (8%)

Query: 417 SRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQS 476
           S     SS S S S S SES   H        + KH R   +   +   KR+K  S S+ 
Sbjct: 195 SEGSDSSSNSSSSSESSSESELEHERSR----RRKHKR---RPKVKRSKKRRKEASSSEE 247

Query: 477 KSRDHSDAAKKHRHERGHHRDRRERSRSFER 507
               H+   K H  ER    ++R    S +R
Sbjct: 248 PRNKHAMNPKGH-SERSDTNEKRSVDSSAKR 277



 Score = 29.6 bits (65), Expect = 7.1
 Identities = 17/81 (20%), Positives = 35/81 (43%)

Query: 427 RSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAK 486
           + +  +HSE      N  S    +  +  + + S R  HKR+    RS+ + ++ S + +
Sbjct: 188 KRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEE 247

Query: 487 KHRHERGHHRDRRERSRSFER 507
                  + +   ERS + E+
Sbjct: 248 PRNKHAMNPKGHSERSDTNEK 268


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 57/189 (30%), Positives = 85/189 (44%), Gaps = 11/189 (5%)

Query: 337 ASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSR 396
           A + +SP   K +E+S +S++ +  K      +  S+      RK     R  RS SRS+
Sbjct: 12  APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERK---RKSDNEGRKHRSRSRSK 68

Query: 397 SRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDD 456
              R  S+  + ++H +   +     S + R R  S      RH        + K +R  
Sbjct: 69  EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK-----ERKSSRGR 123

Query: 457 LKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGG 516
             S +R   +R +SRSR + KSR  S   KK R  R   R ++ RSRS ER  + +    
Sbjct: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSR-SRSRER-KKSRSRSRERKRRIRSRSR 181

Query: 517 SRSGHGRHR 525
           SRS H RHR
Sbjct: 182 SRSRH-RHR 189



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 25/157 (15%)

Query: 338 SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASR--- 394
           SK  S ++ K+EE +    +    ++     +          RK S+   +SRS SR   
Sbjct: 75  SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134

Query: 395 --SRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKH 452
             SRSR R +SRS +  R  +  RSR      R +SRSRS                + + 
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSR-----ERKKSRSRSRE--------------RKRR 175

Query: 453 TRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR 489
            R   +S +RH H R +SRSR++S+SRD     +K R
Sbjct: 176 IRSRSRSRSRHRH-RTRSRSRTRSRSRDRKKRIEKPR 211



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 32/165 (19%)

Query: 362 KKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGT 421
           +K   DR +  K   + V    + S++  S SRSRSR R R   +  R+H          
Sbjct: 14  EKTSPDRDK--KKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH---------- 61

Query: 422 YSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDH 481
                  RSRS S+  RRH +               KSS +H  +    +  S  K R+ 
Sbjct: 62  -------RSRSRSKEGRRHESKD-------------KSSKKHKSEEHNDKEHSSDKGRER 101

Query: 482 SDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
            ++++           +  R RS  RS   +    SRS   +  R
Sbjct: 102 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSR 146


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 71/233 (30%), Positives = 107/233 (45%), Gaps = 29/233 (12%)

Query: 298  LLEKEVEKRKVALQ---EAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPI 354
            LL K++E R  +L+   E  L A  +  D + A   +     +S P    E  +EEK   
Sbjct: 1737 LLPKDME-RLTSLRAGIEGPLLASDVGRDRSAASPVV-----SSMPERASESSSEEKDDY 1790

Query: 355  SINVK-------TVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSR-SRTRSRS--R 404
             I VK       + K +  D+ +  K   + +R  SKRS++S   SR R S +RSR+  R
Sbjct: 1791 EIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKR 1850

Query: 405  SHTPRRHYNNRRSRSGT----YSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSS 460
            S   + H +  RSRS +     SSRSRS+SR      +        H      R   +SS
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSS 1910

Query: 461  NRHGHKRKKSRSRSQS-KSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSK 512
            +R   K  ++RSR+ S +SR H+ + ++     G     R RS S   S +S+
Sbjct: 1911 SRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVG-----RRRSFSISPSRRSR 1958



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 58/189 (30%), Positives = 77/189 (40%), Gaps = 17/189 (8%)

Query: 338  SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRS 397
            S+  S R  ++      S   ++V KE   R    +S     ++    SR++R   R+RS
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922

Query: 398  RT------------RSRSRSHTPRRHYNNRRS-RSGTYSSRSRSRSRSHSESPRRHHNHG 444
            RT            R RSRS   RR ++   S RS T S RSR+ SR  S +P R     
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTP 1981

Query: 445  SPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSR-DHSDAAKKHRHERGHHRDRRERSR 503
            S   +    R    S  R      + RS S S  R   S    + R  R     RR+RSR
Sbjct: 1982 SRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS--PIRRKRSR 2039

Query: 504  SFERSHKSK 512
            S ER    K
Sbjct: 2040 SSERGRSPK 2048



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 10/171 (5%)

Query: 342  SPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRS 401
            S R   +E KS      +T +     R+++SKS  +  +  S RSR+ R    SRSR++S
Sbjct: 1826 SKRSKSSEHKS----RKRTSESRSRARKRSSKSKSHRSQTRS-RSRSRRRRRSSRSRSKS 1880

Query: 402  RSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSES-PRRHHNHGSPHLKAKHTRDDLKSS 460
            R R    R     +R RS  + S+SR R R  S S   R          ++ +R    S 
Sbjct: 1881 RGR----RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSR 1936

Query: 461  NRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKS 511
             R      + RS S S SR     +++ R      R    RSR+  R  ++
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1987



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 58/233 (24%), Positives = 94/233 (40%), Gaps = 25/233 (10%)

Query: 290  TRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAE 349
            + +K +YE+  K  +  +   +  K K +          S+L   S  SK S  +  K  
Sbjct: 1784 SEEKDDYEIFVKVKDTHE---KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT 1840

Query: 350  EKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKR-SRNSRSASRSRSR---------- 398
             +S      ++ K +    Q  S+S        S+R  R+SRS S+SR R          
Sbjct: 1841 SESRSRARKRSSKSKSHRSQTRSRSR-------SRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 399  -TRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRS-RSHSESPRRHHNHGSPHLKAKHTRDD 456
              + RS+S   +R  ++ R    T  +RSR+ S RS S +P R     S   +   +   
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP 1953

Query: 457  LKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR--HERGHHRDRRERSRSFER 507
             + S     + +    RS++ SR     +++ R    R     RR RSRS  R
Sbjct: 1954 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVR 2006



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 7/113 (6%)

Query: 414  NRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSR 473
            +R + S   SS     S S SE    +       +K K T +  K +       K+ +  
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKDDYEIF----VKVKDTHEKSKKNKNRDKGEKEKKRD 1819

Query: 474  SQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
            S  +SR     + +H+  +   R    RSR+ +RS KSK H        R RR
Sbjct: 1820 SSLRSRSKRSKSSEHKSRK---RTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 359  KTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSR 418
            +T  +      + S++P    R  S+RSR      RSRS  R RS S +P R   +R   
Sbjct: 1965 RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPL 2024

Query: 419  SGTYSS----RSRSRSRSHSESPRR 439
               +S     R RSRS     SP+R
Sbjct: 2025 RRRFSRSPIRRKRSRSSERGRSPKR 2049


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 71/233 (30%), Positives = 107/233 (45%), Gaps = 29/233 (12%)

Query: 298  LLEKEVEKRKVALQ---EAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPI 354
            LL K++E R  +L+   E  L A  +  D + A   +     +S P    E  +EEK   
Sbjct: 1737 LLPKDME-RLTSLRAGIEGPLLASDVGRDRSAASPVV-----SSMPERASESSSEEKDDY 1790

Query: 355  SINVK-------TVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSR-SRTRSRS--R 404
             I VK       + K +  D+ +  K   + +R  SKRS++S   SR R S +RSR+  R
Sbjct: 1791 EIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKR 1850

Query: 405  SHTPRRHYNNRRSRSGT----YSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSS 460
            S   + H +  RSRS +     SSRSRS+SR      +        H      R   +SS
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSS 1910

Query: 461  NRHGHKRKKSRSRSQS-KSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSK 512
            +R   K  ++RSR+ S +SR H+ + ++     G     R RS S   S +S+
Sbjct: 1911 SRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVG-----RRRSFSISPSRRSR 1958



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 58/189 (30%), Positives = 77/189 (40%), Gaps = 17/189 (8%)

Query: 338  SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRS 397
            S+  S R  ++      S   ++V KE   R    +S     ++    SR++R   R+RS
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922

Query: 398  RT------------RSRSRSHTPRRHYNNRRS-RSGTYSSRSRSRSRSHSESPRRHHNHG 444
            RT            R RSRS   RR ++   S RS T S RSR+ SR  S +P R     
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTP 1981

Query: 445  SPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSR-DHSDAAKKHRHERGHHRDRRERSR 503
            S   +    R    S  R      + RS S S  R   S    + R  R     RR+RSR
Sbjct: 1982 SRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS--PIRRKRSR 2039

Query: 504  SFERSHKSK 512
            S ER    K
Sbjct: 2040 SSERGRSPK 2048



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 10/171 (5%)

Query: 342  SPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRS 401
            S R   +E KS      +T +     R+++SKS  +  +  S RSR+ R    SRSR++S
Sbjct: 1826 SKRSKSSEHKS----RKRTSESRSRARKRSSKSKSHRSQTRS-RSRSRRRRRSSRSRSKS 1880

Query: 402  RSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSES-PRRHHNHGSPHLKAKHTRDDLKSS 460
            R R    R     +R RS  + S+SR R R  S S   R          ++ +R    S 
Sbjct: 1881 RGR----RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSR 1936

Query: 461  NRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKS 511
             R      + RS S S SR     +++ R      R    RSR+  R  ++
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1987



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 58/233 (24%), Positives = 94/233 (40%), Gaps = 25/233 (10%)

Query: 290  TRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAE 349
            + +K +YE+  K  +  +   +  K K +          S+L   S  SK S  +  K  
Sbjct: 1784 SEEKDDYEIFVKVKDTHE---KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT 1840

Query: 350  EKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKR-SRNSRSASRSRSR---------- 398
             +S      ++ K +    Q  S+S        S+R  R+SRS S+SR R          
Sbjct: 1841 SESRSRARKRSSKSKSHRSQTRSRSR-------SRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 399  -TRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRS-RSHSESPRRHHNHGSPHLKAKHTRDD 456
              + RS+S   +R  ++ R    T  +RSR+ S RS S +P R     S   +   +   
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP 1953

Query: 457  LKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR--HERGHHRDRRERSRSFER 507
             + S     + +    RS++ SR     +++ R    R     RR RSRS  R
Sbjct: 1954 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVR 2006



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 7/113 (6%)

Query: 414  NRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSR 473
            +R + S   SS     S S SE    +       +K K T +  K +       K+ +  
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKDDYEIF----VKVKDTHEKSKKNKNRDKGEKEKKRD 1819

Query: 474  SQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
            S  +SR     + +H+  +   R    RSR+ +RS KSK H        R RR
Sbjct: 1820 SSLRSRSKRSKSSEHKSRK---RTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 359  KTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSR 418
            +T  +      + S++P    R  S+RSR      RSRS  R RS S +P R   +R   
Sbjct: 1965 RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPL 2024

Query: 419  SGTYSS----RSRSRSRSHSESPRR 439
               +S     R RSRS     SP+R
Sbjct: 2025 RRRFSRSPIRRKRSRSSERGRSPKR 2049


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 67/204 (32%), Positives = 92/204 (45%), Gaps = 28/204 (13%)

Query: 344 REVKAEEKSPISINVKTVKKEPEDR-QQASKSPYNGVRKD---SKRSRNSRSASRSRSRT 399
           R  ++ E+       +  K +  DR ++  K    G R+D    K   N R   R RSR 
Sbjct: 328 RRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRE 387

Query: 400 RS---RSRSHTP----------RRHYNNRR-SRSGTYSSRSRSRSRSHSESPRRHHNHGS 445
           RS   RSR              RRH +++R S+     SRSRSR R H  S  R  N G 
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAG- 445

Query: 446 PHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDA---AKKHRHERGHHRDRRERS 502
              K   +R   KSS      ++KS  RS+S S+  +D+   +KK  H     + R+ RS
Sbjct: 446 ---KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK-RS 501

Query: 503 RSFERSHKSKHHGGSRSGHGRHRR 526
           RS ERSHK + H  S+    +H R
Sbjct: 502 RSKERSHK-RDHSDSKDQSDKHDR 524



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 73/278 (26%), Positives = 117/278 (42%), Gaps = 40/278 (14%)

Query: 263 TRPHWF-LLFGTTEEEIQEICIETLRLYTRK-----KPNYELLEKEVEKRKVALQEAKLK 316
           T+  WF  LF      +Q+   + ++   RK     K   E +++ VE+R+     ++  
Sbjct: 209 TKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRR-----SRSP 263

Query: 317 AKGLNPDGTPALSTLGGFSPASKPSSP--REVKAEEKSPISINVKTVKKEPEDRQQASKS 374
            + L+P  +P  S           SS   RE++ E++      ++   KE E  ++ S+S
Sbjct: 264 RRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQ---RLEREAKEREKERRRSRS 320

Query: 375 PYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPR-----RHYNNRRSR-------SGTY 422
              G+ +     R SRS  R RSR+RSR R    R     R   N R R           
Sbjct: 321 IDRGLER-----RRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERG 375

Query: 423 SSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLK-SSNRHGHKRKKSRSRSQSKSRDH 481
           + R + R RS   S  +         K K  +DD +   ++   K++K  SRS+S+ R H
Sbjct: 376 NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH 435

Query: 482 SDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
                     R  +  +R RSRS E+S K K+    +S
Sbjct: 436 ------RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 55/172 (31%), Positives = 82/172 (47%), Gaps = 19/172 (11%)

Query: 344 REVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRS-R 402
           RE   E++S   +  K  K++ +DR+          R D + S+  +  SRSRSR R  R
Sbjct: 386 RERSKEQRSRGEVEEKKHKEDKDDRRH---------RDDKRDSKKEKKHSRSRSRERKHR 436

Query: 403 SRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNR 462
           SRS + R      RSRS   SS+ ++ S+  S    R  + G      K  + +   S  
Sbjct: 437 SRSRS-RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKE 495

Query: 463 HGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHH 514
               RK+SRS+ +S  RDHSD+      ++    DRR RS+S E+  + K H
Sbjct: 496 --KSRKRSRSKERSHKRDHSDS-----KDQSDKHDRR-RSQSIEQESQEKQH 539



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 66/284 (23%), Positives = 107/284 (37%), Gaps = 38/284 (13%)

Query: 267 WFLLFGTTEEEIQEI----CI----ETLRLYTRKKPNYELLEKE--VEKRKVALQEAKLK 316
           WF  F   EE++       C+    E LR +  K   +  L     V  +K   Q+ K +
Sbjct: 177 WFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTR 236

Query: 317 AKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPE---------D 367
            + +  DG      +       +  SPR   +  +SP     ++  +E           +
Sbjct: 237 PRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELE 296

Query: 368 RQQASKSPYNGVRKDSKRSRNSRSASR------SRSRTRSRSRSHTPRRHYNNRRSRSGT 421
           R++  +      ++  K  R SRS  R      SRSR R RSRS +        R R G 
Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS--------RDRKGD 348

Query: 422 YSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDH 481
              R R R + +    RR  ++       +   +  K   R   + K+ RSR + + + H
Sbjct: 349 RRDRDREREKENERGRRRDRDYDK-----ERGNEREKERERSRERSKEQRSRGEVEEKKH 403

Query: 482 SDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHR 525
            +     RH       ++E+  S  RS + KH   SRS +   R
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR 447


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 68/257 (26%), Positives = 120/257 (46%), Gaps = 26/257 (10%)

Query: 273 TTEEEIQEICIETLRLYTRKKPNYELL-EKEVEKRKVALQEAKLKAKGLNPDGTPALSTL 331
           T +EE++    +    + RK+   +LL +K++E+ K   +    +          +LS L
Sbjct: 410 TDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLL 469

Query: 332 GGFSPASKPSSPREVKAEEKSPI-SINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSR 390
                 ++ +    V  ++++P  + +V   KKE +++++  +S  +G       S NSR
Sbjct: 470 -----EAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSR-SGSSSSGSSSSNSR 523

Query: 391 SASRSRS-----------RTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRR 439
           ++S S +            +R+ SRS +P+R   + RSRS T  +R RSRSRS+S   + 
Sbjct: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR-RSRSRSYSRRIKI 582

Query: 440 HHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRR 499
             N     +K +  R   ++S     +R +S SR + +SR  S   + +R  R   RDRR
Sbjct: 583 ESNRA--RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRR 640

Query: 500 ----ERSRSFERSHKSK 512
               +R      SHK K
Sbjct: 641 KIDDQRGNLSGNSHKHK 657



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 50/188 (26%), Positives = 78/188 (41%), Gaps = 9/188 (4%)

Query: 329 STLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRN 388
           S+ G    +S+ SSP+  K   +S  S  +K  +       +  K   N  R   +  R 
Sbjct: 538 SSSGSSRTSSRSSSPKRKKRHSRSR-SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRR 596

Query: 389 SRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPR-----RHHNH 443
           S   S  R R R+RS S   RR  +  R R    +SRSRSR R   +  R       H H
Sbjct: 597 SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656

Query: 444 GSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAK---KHRHERGHHRDRRE 500
                + +  ++  +S ++   K+ K R R Q K ++     +   K   +    + +RE
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE 716

Query: 501 RSRSFERS 508
             R+F RS
Sbjct: 717 SERTFSRS 724



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 10/179 (5%)

Query: 338 SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRS 397
           S+  S     +   S  S    TV          S    +      ++ R+SRS S +  
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIK 567

Query: 398 RTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDL 457
             RSRSRS++ R    + R+R      R R RS  +S    R  N  SP  + + +R   
Sbjct: 568 ARRSRSRSYSRRIKIESNRAR---VKIRDRRRSNRNSIERERRRNR-SPSRERRRSRS-- 621

Query: 458 KSSNRHGHKRKKSRSRSQSKSRDH----SDAAKKHRHERGHHRDRRERSRSFERSHKSK 512
           +S +R  ++  +SRSR + K  D     S  + KH+ E      ++ERSRS ++  K K
Sbjct: 622 RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKK 680



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 58/210 (27%), Positives = 86/210 (40%), Gaps = 25/210 (11%)

Query: 304 EKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKK 363
           EK K     +   + G +   +   ST    S +S  SS    +   +S           
Sbjct: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSS--------SP 552

Query: 364 EPEDRQQASKSPYNGVRKDSKRSRNSR---SASRSRSRTRSRSRSHTPRRHYNNRRSRSG 420
           + + R   S+SP    R+   RS + R    ++R+R + R R RS+        RR+RS 
Sbjct: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS- 611

Query: 421 TYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLK---SSNRHGHK-------RKKS 470
              SR R RSRS S   RR +       + +   DD +   S N H HK       RKK 
Sbjct: 612 --PSRERRRSRSRSRD-RRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668

Query: 471 RSRSQSKSRDHSDAAKKHRHERGHHRDRRE 500
           RSRS  K R   D  ++   ++   + +RE
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKRE 698



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 11/147 (7%)

Query: 376 YNGVRKDSKRSRN-SRSASRSRSRT-RSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSH 433
           + G  K+ +R +  SRS  + R +  + R R    R+    R  +   +SS+   R +  
Sbjct: 656 HKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD-DRLKRK 714

Query: 434 SESPRRHHNHGSPHLKA-KH-TRDD-----LKSSNRHGHKRKKSRSRSQSKSRDHSDAAK 486
            ES R     GS  +K  +H +R D      K S +H       RS S+S        AK
Sbjct: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774

Query: 487 KHRHERGHHRDRRERS-RSFERSHKSK 512
           K +H R    ++ +RS +   R HKSK
Sbjct: 775 KPKHSRSRSVEKSQRSGKKASRKHKSK 801



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 40/145 (27%), Positives = 55/145 (37%), Gaps = 11/145 (7%)

Query: 344 REVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRS 403
           +E K E    I  + K   KE E  Q   K       KD K S       R R   R+ S
Sbjct: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS 722

Query: 404 RS---------HTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTR 454
           RS         H  R+      ++     S S S  RS SESP       +   K KH+R
Sbjct: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK--KPKHSR 780

Query: 455 DDLKSSNRHGHKRKKSRSRSQSKSR 479
                 ++   K+   + +S+S+SR
Sbjct: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805


>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 68/257 (26%), Positives = 120/257 (46%), Gaps = 26/257 (10%)

Query: 273 TTEEEIQEICIETLRLYTRKKPNYELL-EKEVEKRKVALQEAKLKAKGLNPDGTPALSTL 331
           T +EE++    +    + RK+   +LL +K++E+ K   +    +          +LS L
Sbjct: 410 TDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLL 469

Query: 332 GGFSPASKPSSPREVKAEEKSPI-SINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSR 390
                 ++ +    V  ++++P  + +V   KKE +++++  +S  +G       S NSR
Sbjct: 470 -----EAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSR-SGSSSSGSSSSNSR 523

Query: 391 SASRSRS-----------RTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRR 439
           ++S S +            +R+ SRS +P+R   + RSRS T  +R RSRSRS+S   + 
Sbjct: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR-RSRSRSYSRRIKI 582

Query: 440 HHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRR 499
             N     +K +  R   ++S     +R +S SR + +SR  S   + +R  R   RDRR
Sbjct: 583 ESNRA--RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRR 640

Query: 500 ----ERSRSFERSHKSK 512
               +R      SHK K
Sbjct: 641 KIDDQRGNLSGNSHKHK 657



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 50/188 (26%), Positives = 78/188 (41%), Gaps = 9/188 (4%)

Query: 329 STLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRN 388
           S+ G    +S+ SSP+  K   +S  S  +K  +       +  K   N  R   +  R 
Sbjct: 538 SSSGSSRTSSRSSSPKRKKRHSRSR-SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRR 596

Query: 389 SRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPR-----RHHNH 443
           S   S  R R R+RS S   RR  +  R R    +SRSRSR R   +  R       H H
Sbjct: 597 SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656

Query: 444 GSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAK---KHRHERGHHRDRRE 500
                + +  ++  +S ++   K+ K R R Q K ++     +   K   +    + +RE
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE 716

Query: 501 RSRSFERS 508
             R+F RS
Sbjct: 717 SERTFSRS 724



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 10/179 (5%)

Query: 338 SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRS 397
           S+  S     +   S  S    TV          S    +      ++ R+SRS S +  
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIK 567

Query: 398 RTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDL 457
             RSRSRS++ R    + R+R      R R RS  +S    R  N  SP  + + +R   
Sbjct: 568 ARRSRSRSYSRRIKIESNRAR---VKIRDRRRSNRNSIERERRRNR-SPSRERRRSRS-- 621

Query: 458 KSSNRHGHKRKKSRSRSQSKSRDH----SDAAKKHRHERGHHRDRRERSRSFERSHKSK 512
           +S +R  ++  +SRSR + K  D     S  + KH+ E      ++ERSRS ++  K K
Sbjct: 622 RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKK 680



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 58/210 (27%), Positives = 86/210 (40%), Gaps = 25/210 (11%)

Query: 304 EKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKK 363
           EK K     +   + G +   +   ST    S +S  SS    +   +S           
Sbjct: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSS--------SP 552

Query: 364 EPEDRQQASKSPYNGVRKDSKRSRNSR---SASRSRSRTRSRSRSHTPRRHYNNRRSRSG 420
           + + R   S+SP    R+   RS + R    ++R+R + R R RS+        RR+RS 
Sbjct: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS- 611

Query: 421 TYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLK---SSNRHGHK-------RKKS 470
              SR R RSRS S   RR +       + +   DD +   S N H HK       RKK 
Sbjct: 612 --PSRERRRSRSRSRD-RRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668

Query: 471 RSRSQSKSRDHSDAAKKHRHERGHHRDRRE 500
           RSRS  K R   D  ++   ++   + +RE
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKRE 698



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 11/147 (7%)

Query: 376 YNGVRKDSKRSRN-SRSASRSRSRT-RSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSH 433
           + G  K+ +R +  SRS  + R +  + R R    R+    R  +   +SS+   R +  
Sbjct: 656 HKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD-DRLKRK 714

Query: 434 SESPRRHHNHGSPHLKA-KH-TRDD-----LKSSNRHGHKRKKSRSRSQSKSRDHSDAAK 486
            ES R     GS  +K  +H +R D      K S +H       RS S+S        AK
Sbjct: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774

Query: 487 KHRHERGHHRDRRERS-RSFERSHKSK 512
           K +H R    ++ +RS +   R HKSK
Sbjct: 775 KPKHSRSRSVEKSQRSGKKASRKHKSK 801



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 40/145 (27%), Positives = 55/145 (37%), Gaps = 11/145 (7%)

Query: 344 REVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRS 403
           +E K E    I  + K   KE E  Q   K       KD K S       R R   R+ S
Sbjct: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS 722

Query: 404 RS---------HTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTR 454
           RS         H  R+      ++     S S S  RS SESP       +   K KH+R
Sbjct: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK--KPKHSR 780

Query: 455 DDLKSSNRHGHKRKKSRSRSQSKSR 479
                 ++   K+   + +S+S+SR
Sbjct: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 72/219 (32%), Positives = 96/219 (43%), Gaps = 21/219 (9%)

Query: 327  ALSTLGGFSPASK----PSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKD 382
            +LS  G  SP+ +    PS  R     E+S  S + ++ +   E R ++     +  R  
Sbjct: 1624 SLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSH--RGP 1681

Query: 383  SKRSRNSRSASRSRSRTRSRSRSHTPRRHYN--NRRSRS-GTYSSRSRSRSRSHSESPRR 439
            S+RS  S S  R RS ++   R  + RRH++   R  RS    S RS S    HS S R 
Sbjct: 1682 SERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERS 1741

Query: 440  HHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR--HERGHH-- 495
            HH+       +   R     S R      + R RS S+ R HS + K H    ER HH  
Sbjct: 1742 HHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSP 1801

Query: 496  RDRR-----ERSRS--FERSHKSKHHGGS-RSGHGRHRR 526
             +RR     ERSR    ERSH+S     S RS    HRR
Sbjct: 1802 SERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR 1840



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 51/191 (26%), Positives = 78/191 (40%), Gaps = 8/191 (4%)

Query: 342  SPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYN-GVRKDSKRSRNSRSASRSRSRTR 400
            SP E +    S  S    + ++     +++ +SP     R  S+RS +S S     S + 
Sbjct: 1688 SPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSE 1747

Query: 401  SRSRSHTPRRHYN-NRRSRSGTYSSRSRSRS--RSHSESPRRHHNHG--SPHLKAKHTRD 455
             R  S + R H + + RS       R RS S  R HS S + HH+    S H  ++  R 
Sbjct: 1748 RRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRH 1807

Query: 456  DLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSH--KSKH 513
                 +RH    +  RS S+ +S    + + +   ER H    +      ERS    S+ 
Sbjct: 1808 SPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSER 1867

Query: 514  HGGSRSGHGRH 524
             G S SG   H
Sbjct: 1868 RGHSSSGKTCH 1878



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 52/175 (29%), Positives = 73/175 (41%), Gaps = 23/175 (13%)

Query: 368  RQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP--RRHYNNRRSRSGTYSSR 425
            R++  + P    R +    RN RS S    R+    R H+P  R H +  R    + S R
Sbjct: 1546 RERTPRGPSERTRHNPSW-RNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604

Query: 426  S-RSRS-RSHSESPRRH-HNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHS 482
            S RS S R+H   P R  H+     L +   R     S R  H   +   RS S+    S
Sbjct: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS 1664

Query: 483  DAAKKHRH----------ERGH--HRDRRERSRSFERSHKS----KHHGGSRSGH 521
             + ++HR           ER H    +RR RS S +RSH+     +HH  S+  H
Sbjct: 1665 SSERRHRSPSQRSHRGPSERSHCSPSERRHRSPS-QRSHRGPSERRHHSPSKRSH 1718



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 48/164 (29%), Positives = 63/164 (38%), Gaps = 13/164 (7%)

Query: 365  PEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSS 424
            P +R   S S  N      +RS +S S     S ++   R  + RRH++         S 
Sbjct: 1601 PSERSWRSPSQRNHC-SPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSER-----SH 1654

Query: 425  RSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDA 484
            RS S     S S RRH +      +    R     S R      +   R  S+ R HS +
Sbjct: 1655 RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPS 1714

Query: 485  AKKHRHE-RGHHRDRRERSRSF--ERSHKS----KHHGGSRSGH 521
             + HR   R  HR   ERS     ERSH S    +HH  S   H
Sbjct: 1715 KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSH 1758



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 8/150 (5%)

Query: 380  RKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRR 439
            R  S+R+R++ S    RS +    RS   RRH++  +    + S ++ S     S     
Sbjct: 1551 RGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPS 1610

Query: 440  HHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHR--HERGHHRD 497
              NH SP  ++ H+      S R  H   +   R  S+ R HS + + HR   ER H   
Sbjct: 1611 QRNHCSPPERSCHS-----LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSS 1665

Query: 498  RRERSRS-FERSHKSKHHGGSRSGHGRHRR 526
               R RS  +RSH+        S   R  R
Sbjct: 1666 SERRHRSPSQRSHRGPSERSHCSPSERRHR 1695



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 64/294 (21%), Positives = 99/294 (33%), Gaps = 28/294 (9%)

Query: 255  RALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAK 314
            R L++P PT     + F T         ++       KK  Y       E + ++    +
Sbjct: 1450 RPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTR 1509

Query: 315  LKAKGLNPDGTPALSTLG---------------GFSPASKPSSPREVKAEEKSPISINVK 359
            ++A+G    G+P   T                  F     P  P E      S  +    
Sbjct: 1510 VQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSP 1569

Query: 360  TVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRS 419
            + + +    ++   SP         R  +S  + RS      R+    P R  ++   R 
Sbjct: 1570 SERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSER- 1628

Query: 420  GTYSSRSRSR----SRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSR-S 474
            G +S   RS      R H     R H   S       +    +S ++  H+    RS  S
Sbjct: 1629 GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS 1688

Query: 475  QSKSRDHSDAAKKHR--HERGHHRDRRERSRS-FERSHKS----KHHGGSRSGH 521
             S+ R  S + + HR   ER HH   +   RS   RSH+S     HH  S   H
Sbjct: 1689 PSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSH 1742



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 53/192 (27%), Positives = 70/192 (36%), Gaps = 25/192 (13%)

Query: 340  PSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRT 399
            PS  R     E+S  S + ++    P +R+  S S     R  S   ++  S S     +
Sbjct: 1745 PSERRHHSPSERSHCSPSERS-HCSPSERRHRSPSER---RHHSPSEKSHHSPSERSHHS 1800

Query: 400  RSRSRSHTP---RRHYNNRRSRSGTYSSRS-RSRSRSHSESPRRHHNHGSPHLKAKHTRD 455
             S  R H+P    RH    RS       RS RS  RSH     R H+       +   R 
Sbjct: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860

Query: 456  DLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSK--- 512
                S R GH        S S    HS + + HR   G       + R+ ERSH+S    
Sbjct: 1861 RCSPSERRGH--------SSSGKTCHSPSERSHRSPSG-----MRQGRTSERSHRSSCER 1907

Query: 513  -HHGGSRSGHGR 523
              H  S    GR
Sbjct: 1908 TRHSPSEMRPGR 1919



 Score = 29.6 bits (65), Expect = 7.1
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 14/132 (10%)

Query: 384  KRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNH 443
            +RSR S S  R  S +     S + R H    RS SG    R+  RS   S    RH   
Sbjct: 1858 ERSRCSPSERRGHSSSGKTCHSPSERSH----RSPSGMRQGRTSERSHRSSCERTRH--- 1910

Query: 444  GSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSR 503
             SP       R    S   H    ++SR     +   +S   ++  H     RD + ++ 
Sbjct: 1911 -SP----SEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLS--RDFKNQTT 1963

Query: 504  SFERSHKSKHHG 515
                +HK+   G
Sbjct: 1964 LLGTTHKNPKAG 1975


>gi|16905517 FUS interacting protein (serine-arginine rich) 1
           isoform 2 [Homo sapiens]
          Length = 262

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 58/158 (36%), Positives = 78/158 (49%), Gaps = 10/158 (6%)

Query: 363 KEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTY 422
           K  E R   S S Y+    D  R R SRS S  R R+RSRS  +  RR Y+ R SR    
Sbjct: 97  KAKEGRNVYSSSRYD----DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRP--- 149

Query: 423 SSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRK-KSRSRSQSKSRDH 481
           + R R RSRSHS++ R  H + S      ++R   KS  +   K K +SRS S +K+R  
Sbjct: 150 TGRPR-RSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208

Query: 482 SDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
           S    K  ++ G   ++  R +   RS KS+    SRS
Sbjct: 209 SKTDSKTHYKSGSRYEKESRKKEPPRS-KSQSRSQSRS 245



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 7/88 (7%)

Query: 362 KKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRR---HYNNRRSR 418
           + +   R ++   P    +K+ K    SRSAS +++R  S++ S T  +    Y     +
Sbjct: 174 RSKSNSRSRSKSQP----KKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRK 229

Query: 419 SGTYSSRSRSRSRSHSESPRRHHNHGSP 446
                S+S+SRS+S S S  R  +  SP
Sbjct: 230 KEPPRSKSQSRSQSRSRSKSRSRSWTSP 257



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 7/82 (8%)

Query: 362 KKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGT 421
           KKE + + ++  + +   R  SK   +S++  +S SR    SR   P R  +  RS+S  
Sbjct: 188 KKEMKAKSRSRSASHTKTRGTSKT--DSKTHYKSGSRYEKESRKKEPPRSKSQSRSQS-- 243

Query: 422 YSSRSRSRSRSHSESPRRHHNH 443
              RSRS+SRS S +  +   H
Sbjct: 244 ---RSRSKSRSRSWTSPKSSGH 262



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 37/113 (32%), Positives = 47/113 (41%), Gaps = 26/113 (23%)

Query: 415 RRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRS 474
           RRSRS +Y  R RSRSRS   + RR +   SP                  + R   R R 
Sbjct: 117 RRSRSRSYERR-RSRSRSFDYNYRRSY---SPR-----------------NSRPTGRPR- 154

Query: 475 QSKSRDHSDAAK-KHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
             +SR HSD  + KHR+          RSRS +   K +    SRS    H +
Sbjct: 155 --RSRSHSDNDRFKHRNRSFSRSKSNSRSRS-KSQPKKEMKAKSRSRSASHTK 204



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 4/79 (5%)

Query: 448 LKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFER 507
           ++ +  + D K+ N+   K K+ R+   S   D  D  ++ R  R + R RR RSRSF+ 
Sbjct: 81  IEIQFAQGDRKTPNQM--KAKEGRNVYSSSRYDDYDRYRRSR-SRSYER-RRSRSRSFDY 136

Query: 508 SHKSKHHGGSRSGHGRHRR 526
           +++  +   +    GR RR
Sbjct: 137 NYRRSYSPRNSRPTGRPRR 155



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 24/104 (23%)

Query: 338 SKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRS 397
           SK    +E+KA+ +S  + + KT      D    SK+ Y    +  K SR  +   RS+S
Sbjct: 183 SKSQPKKEMKAKSRSRSASHTKTRGTSKTD----SKTHYKSGSRYEKESRK-KEPPRSKS 237

Query: 398 RTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHH 441
           ++RS+SR                   SRS+SRSRS +      H
Sbjct: 238 QSRSQSR-------------------SRSKSRSRSWTSPKSSGH 262


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 17/185 (9%)

Query: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRK-DSKRSRNSRSASRSRSRTRSRSR--S 405
           E +S IS  ++  KKE + R   S+S     R   S R R SRS SR RS ++SRSR  S
Sbjct: 228 EAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRS 287

Query: 406 HTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGH 465
            +PRR  ++ R R     SRS S++R   +  +      +P       R    +S     
Sbjct: 288 KSPRRRRSHSRERGRR--SRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345

Query: 466 KRKKSRSRSQSKSRD------HSDAAKKHRHERG------HHRDRRERSRSFERSHKSKH 513
           +R +S +RS  K R        S + ++H+ E+         RD RERS S ++  K K 
Sbjct: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE 405

Query: 514 HGGSR 518
               R
Sbjct: 406 KDRER 410



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 50/156 (32%), Positives = 74/156 (47%), Gaps = 15/156 (9%)

Query: 355 SINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNN 414
           S  ++   K   + Q    +     +K+ KR R+SRS SRSR R    S  H   R  + 
Sbjct: 216 SKEIEEAMKRVREAQSLISAAIEPDKKEEKR-RHSRSRSRSRRRRTPSSSRHRRSRSRSR 274

Query: 415 RRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRS 474
           RR       S S+SRSR  S+SPRR  +H     + + +R   K+ ++    ++K RS++
Sbjct: 275 RR-------SHSKSRSRRRSKSPRRRRSHSRE--RGRRSRSTSKTRDKKKEDKEKKRSKT 325

Query: 475 QSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHK 510
             KS   +  ++    ER     RR RSRS  RS K
Sbjct: 326 PPKSYSTARRSRSASRER-----RRRRSRSGTRSPK 356



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 26/214 (12%)

Query: 301 KEVEKRKVALQEAK-LKAKGLNPDGTPALSTLGGFSPASK----PSSPREVKAEEKSPIS 355
           KE+E+    ++EA+ L +  + PD              S+    PSS R  ++  +S   
Sbjct: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276

Query: 356 INVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRS---RSRSHTPRRHY 412
            + K+  +      + SKSP        +R R SRS S++R + +    + RS TP + Y
Sbjct: 277 SHSKSRSR------RRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330

Query: 413 NN-RRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSR 471
           +  RRSRS +   R R RSRS + SP++     SP  K        +S +   HK++K +
Sbjct: 331 STARRSRSAS-RERRRRRSRSGTRSPKKPR---SPKRKLS------RSPSPRRHKKEKKK 380

Query: 472 SRSQSKSRDHSD-AAKKHRHERGHHRDRRERSRS 504
            + + +SRD  + +  K +  +   +DR  +S S
Sbjct: 381 DKDKERSRDERERSTSKKKKSKDKEKDRERKSES 414



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 29/134 (21%)

Query: 379 VRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPR 438
           ++ D+       +  R R      S +  P +    RR         SRSRSRS      
Sbjct: 210 LKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRR--------HSRSRSRSR----- 256

Query: 439 RHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDR 498
                          R    SS+RH   R +SR RS SKSR     +K  R  R H R+R
Sbjct: 257 ---------------RRRTPSSSRHRRSRSRSRRRSHSKSRSRR-RSKSPRRRRSHSRER 300

Query: 499 RERSRSFERSHKSK 512
             RSRS  ++   K
Sbjct: 301 GRRSRSTSKTRDKK 314



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 466 KRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHR 525
           KR+ SRSRS+S+ R    ++   RH R   R RR RS S  RS +       R  H R R
Sbjct: 245 KRRHSRSRSRSRRRRTPSSS---RHRRSRSRSRR-RSHSKSRSRRRSKSPRRRRSHSRER 300


>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
           sapiens]
          Length = 747

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 54/151 (35%), Positives = 76/151 (50%), Gaps = 19/151 (12%)

Query: 381 KDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRH 440
           + + RS +SRS SRS+S +RSRSRSH+ ++ Y++ RSRS TY SRSRSR R +S   RR 
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSS-RSRSRTY-SRSRSRDRMYSRDYRRD 60

Query: 441 HNHG----SPHLKAKHTRDDLKSSNRHGHK--------RKKSRSRSQSKSRDHSDAAKKH 488
           + +      P+      R   +      H+        R+ SRS  + +SR  S   +  
Sbjct: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120

Query: 489 RHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
             +R      R RSR   RS +S     SRS
Sbjct: 121 SSQRS-----RSRSRRSYRSSRSPRSSSSRS 146



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 48/151 (31%), Positives = 61/151 (40%), Gaps = 12/151 (7%)

Query: 372 SKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP------RRHYNNRRSRSGTYSSR 425
           S+S  +   +    SR  R +SRSRSRT SRSRS         RR Y N R     Y  R
Sbjct: 15  SRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYR 74

Query: 426 SRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKS-RSRSQSKSRDHSDA 484
            R R        R H     P    +H+R     S R G  R +S + RS S  R  S +
Sbjct: 75  GRGRGYYQGGGGRYHRGGYRPVWNRRHSR-----SPRRGRSRSRSPKRRSVSSQRSRSRS 129

Query: 485 AKKHRHERGHHRDRRERSRSFERSHKSKHHG 515
            + +R  R         S  + +S  SK  G
Sbjct: 130 RRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/145 (22%), Positives = 57/145 (39%), Gaps = 3/145 (2%)

Query: 360 TVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRS 419
           T +K PE  ++   SP + +RK ++ +   R       +   + R  +    ++  R R 
Sbjct: 471 TRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 529

Query: 420 GTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQS--K 477
                R  S+    S   R+       + + K  +DD K      H R  S S S S   
Sbjct: 530 ERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPS 589

Query: 478 SRDHSDAAKKHRHERGHHRDRRERS 502
           SR+  ++ K+   E   H + +E S
Sbjct: 590 SREEKESKKEREEEFKTHHEMKEYS 614



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 25/112 (22%)

Query: 416 RSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQ 475
           RS S ++SSRS+SRS+S S S  R H+                   R      +SRSR+ 
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHS-------------------RKKRYSSRSRSRTY 43

Query: 476 SKSRDHSDAAKKHRHERGHHRD-RRERSRSFERSHKSKHHGGSRSGHGRHRR 526
           S+SR     ++   + R + RD R  R       ++ +  G  + G GR+ R
Sbjct: 44  SRSR-----SRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHR 90



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 389 SRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHL 448
           +R  SRS  R RSRSRS   RR  +++RSRS +  S   SRS   S S        SP  
Sbjct: 98  NRRHSRSPRRGRSRSRS-PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVS 156

Query: 449 KAKHTRD-DLKSSNRHGHKRKKSRSRSQSKSRD 480
           K + +++   K +     +    +S+SQ + +D
Sbjct: 157 KRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 189



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 365 PEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSS 424
           P   ++ S+SP  G  +     R S S+ RSRSR+R   RS+   R   +  SRS +  S
Sbjct: 95  PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSR---RSYRSSRSPRSSSSRSSSPYS 151

Query: 425 RSRSRSRSHSESPRRHHNHGSPH----LKAKHTRDDLKSSNRH 463
           +S    R  S+  +     G P     LK+K ++++ K +  H
Sbjct: 152 KSPVSKRRGSQEKQTKKAEGEPQEESPLKSK-SQEEPKDTFEH 193



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 16/99 (16%)

Query: 395 SRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSR-SRSHSESPRRHHNH-GSPHLKAKH 452
           SRS  R RSRS +P+R     RS S +  SRSRSR S   S SPR   +   SP+ K+  
Sbjct: 102 SRSPRRGRSRSRSPKR-----RSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-- 153

Query: 453 TRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHE 491
                  S R G + K+++ +++ + ++ S    K + E
Sbjct: 154 -----PVSKRRGSQEKQTK-KAEGEPQEESPLKSKSQEE 186


>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 920

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 54/151 (35%), Positives = 76/151 (50%), Gaps = 19/151 (12%)

Query: 381 KDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRH 440
           + + RS +SRS SRS+S +RSRSRSH+ ++ Y++ RSRS TY SRSRSR R +S   RR 
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSS-RSRSRTY-SRSRSRDRMYSRDYRRD 60

Query: 441 HNHG----SPHLKAKHTRDDLKSSNRHGHK--------RKKSRSRSQSKSRDHSDAAKKH 488
           + +      P+      R   +      H+        R+ SRS  + +SR  S   +  
Sbjct: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120

Query: 489 RHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
             +R      R RSR   RS +S     SRS
Sbjct: 121 SSQRS-----RSRSRRSYRSSRSPRSSSSRS 146



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 48/151 (31%), Positives = 61/151 (40%), Gaps = 12/151 (7%)

Query: 372 SKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP------RRHYNNRRSRSGTYSSR 425
           S+S  +   +    SR  R +SRSRSRT SRSRS         RR Y N R     Y  R
Sbjct: 15  SRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYR 74

Query: 426 SRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKS-RSRSQSKSRDHSDA 484
            R R        R H     P    +H+R     S R G  R +S + RS S  R  S +
Sbjct: 75  GRGRGYYQGGGGRYHRGGYRPVWNRRHSR-----SPRRGRSRSRSPKRRSVSSQRSRSRS 129

Query: 485 AKKHRHERGHHRDRRERSRSFERSHKSKHHG 515
            + +R  R         S  + +S  SK  G
Sbjct: 130 RRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/145 (22%), Positives = 57/145 (39%), Gaps = 3/145 (2%)

Query: 360 TVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRS 419
           T +K PE  ++   SP + +RK ++ +   R       +   + R  +    ++  R R 
Sbjct: 644 TRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 702

Query: 420 GTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQS--K 477
                R  S+    S   R+       + + K  +DD K      H R  S S S S   
Sbjct: 703 ERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPS 762

Query: 478 SRDHSDAAKKHRHERGHHRDRRERS 502
           SR+  ++ K+   E   H + +E S
Sbjct: 763 SREEKESKKEREEEFKTHHEMKEYS 787



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 25/112 (22%)

Query: 416 RSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQ 475
           RS S ++SSRS+SRS+S S S  R H+                   R      +SRSR+ 
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHS-------------------RKKRYSSRSRSRTY 43

Query: 476 SKSRDHSDAAKKHRHERGHHRD-RRERSRSFERSHKSKHHGGSRSGHGRHRR 526
           S+SR     ++   + R + RD R  R       ++ +  G  + G GR+ R
Sbjct: 44  SRSR-----SRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHR 90



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 389 SRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHL 448
           +R  SRS  R RSRSRS   RR  +++RSRS +  S   SRS   S S        SP  
Sbjct: 98  NRRHSRSPRRGRSRSRS-PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVS 156

Query: 449 KAKHTRD-DLKSSNRHGHKRKKSRSRSQSKSRD 480
           K + +++   K +     +    +S+SQ + +D
Sbjct: 157 KRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 189



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 365 PEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSS 424
           P   ++ S+SP  G  +     R S S+ RSRSR+R   RS+   R   +  SRS +  S
Sbjct: 95  PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSR---RSYRSSRSPRSSSSRSSSPYS 151

Query: 425 RSRSRSRSHSESPRRHHNHGSPH----LKAKHTRDDLKSSNRH 463
           +S    R  S+  +     G P     LK+K ++++ K +  H
Sbjct: 152 KSPVSKRRGSQEKQTKKAEGEPQEESPLKSK-SQEEPKDTFEH 193



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 16/99 (16%)

Query: 395 SRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSR-SRSHSESPRRHHNH-GSPHLKAKH 452
           SRS  R RSRS +P+R     RS S +  SRSRSR S   S SPR   +   SP+ K+  
Sbjct: 102 SRSPRRGRSRSRSPKR-----RSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-- 153

Query: 453 TRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHE 491
                  S R G + K+++ +++ + ++ S    K + E
Sbjct: 154 -----PVSKRRGSQEKQTK-KAEGEPQEESPLKSKSQEE 186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.128    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,567,950
Number of Sequences: 37866
Number of extensions: 980011
Number of successful extensions: 18088
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 265
Number of HSP's successfully gapped in prelim test: 388
Number of HSP's that attempted gapping in prelim test: 8562
Number of HSP's gapped (non-prelim): 3600
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press