Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 9845285
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide
1 [Homo sapiens]
(512 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide ... 1020 0.0
gi|62952502 cytochrome P450, family 26, subfamily C, polypeptide... 534 e-152
gi|16933530 cytochrome P450, family 26, subfamily A, polypeptide... 401 e-112
gi|16933528 cytochrome P450, family 26, subfamily A, polypeptide... 354 9e-98
gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide ... 114 3e-25
gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide ... 109 5e-24
gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7... 107 3e-23
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5... 106 6e-23
gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide ... 105 1e-22
gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide ... 102 1e-21
gi|4503243 cytochrome P450, family 51, subfamily A, polypeptide ... 98 2e-20
gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide... 98 2e-20
gi|30023836 cytochrome P450 4Z1 [Homo sapiens] 95 1e-19
gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11... 93 5e-19
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11... 93 5e-19
gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide... 93 7e-19
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide... 92 1e-18
gi|5729796 cytochrome P450, family 46 [Homo sapiens] 90 4e-18
gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide... 90 4e-18
gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide... 90 4e-18
gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide ... 89 7e-18
gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide ... 88 2e-17
gi|225903399 cytochrome P450, family 51, subfamily A, polypeptid... 87 5e-17
gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8... 85 1e-16
gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide ... 84 2e-16
gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide... 79 8e-15
gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide... 79 8e-15
gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide ... 79 1e-14
gi|7949031 cytochrome P450, family 2, subfamily B, polypeptide 6... 79 1e-14
gi|13449277 cytochrome P450, family 2, subfamily S, polypeptide ... 78 2e-14
>gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide 1
[Homo sapiens]
Length = 512
Score = 1020 bits (2638), Expect = 0.0
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIG 60
MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIG
Sbjct: 1 MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIG 60
Query: 61 ETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRS 120
ETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRS
Sbjct: 61 ETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRS 120
Query: 121 TRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAIN 180
TRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAIN
Sbjct: 121 TRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAIN 180
Query: 181 VYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQAR 240
VYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQAR
Sbjct: 181 VYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQAR 240
Query: 241 QILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYAT 300
QILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYAT
Sbjct: 241 QILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYAT 300
Query: 301 TASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKE 360
TASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKE
Sbjct: 301 TASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKE 360
Query: 361 VMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQA 420
VMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQA
Sbjct: 361 VMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQA 420
Query: 421 RSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVL 480
RSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVL
Sbjct: 421 RSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVL 480
Query: 481 HPVDGLSVKFFGLDSNQNEILPETEAMLSATV 512
HPVDGLSVKFFGLDSNQNEILPETEAMLSATV
Sbjct: 481 HPVDGLSVKFFGLDSNQNEILPETEAMLSATV 512
>gi|62952502 cytochrome P450, family 26, subfamily C, polypeptide 1
[Homo sapiens]
Length = 522
Score = 534 bits (1375), Expect = e-152
Identities = 266/507 (52%), Positives = 359/507 (70%), Gaps = 18/507 (3%)
Query: 5 GLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGH 64
GL +S L L+ LLL+++Q LW LRW +RD++ LP+PKGSMG+P GET H
Sbjct: 5 GLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLH 64
Query: 65 WLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRML 124
WL+QGS F SSRRE+YG VFKTHLLGRP+IRV+GAENVR IL+GEH LV ++WP+S +L
Sbjct: 65 WLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHIL 124
Query: 125 LGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQE 184
LG +T+ ++G+ HR +RKV +++FS ALE Y+P++Q ++ +R+W + ++VY
Sbjct: 125 LGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDA 184
Query: 185 AQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQARQILQ 244
++ LTFRMA R+LLG + E L ++Q V+N+FSLP+D+PFSG R+GI+AR L
Sbjct: 185 SKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLH 244
Query: 245 KGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASA 304
+ LE AI EKL + + DALDL+I S++E G E +MQELK+ +EL+FAA+ TTASA
Sbjct: 245 RHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASA 304
Query: 305 STSLIMQLLKHPTVLEKLRDELRAHGILHSGGCP---------------CEGTLRLDTLS 349
STSL++ LL+HP + K+R+EL A G+ + GC CE L L L
Sbjct: 305 STSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALG 364
Query: 350 GLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKD- 408
LRY+DCV+KEV+RL P+SGGYRT L+TFELDG+QIPKGWSVMYSIRDTH+TA V++
Sbjct: 365 RLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSP 424
Query: 409 VNVFDPDRFSQARSEDK--DGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFEL 466
FDP+RF AR + + RFHY+PFGGG R+CLG+ LA+ L++LAVEL T+R+EL
Sbjct: 425 PEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWEL 484
Query: 467 ATRTFPRITLVPVLHPVDGLSVKFFGL 493
AT FP + VP++HPVDGL + F L
Sbjct: 485 ATPAFPAMQTVPIVHPVDGLRLFFHPL 511
>gi|16933530 cytochrome P450, family 26, subfamily A, polypeptide 1
isoform 1 [Homo sapiens]
Length = 497
Score = 401 bits (1031), Expect = e-112
Identities = 216/494 (43%), Positives = 306/494 (61%), Gaps = 13/494 (2%)
Query: 6 LDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHW 65
+ L + LA+ V LL + +LW L + RD+SC LP+P G+MGFP GET
Sbjct: 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQM 60
Query: 66 LLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLL 125
+LQ F +R KYG ++KTHL GRP +RV GA+NVR+IL+GEH LVS WP S R +L
Sbjct: 61 VLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTIL 120
Query: 126 GPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPE-AINVYQE 184
G +SN H+ ++KV + FS EALE Y+P I + +L W S E + VY E
Sbjct: 121 GSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPE 180
Query: 185 AQKLTFRMAIRVLLG----FSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQAR 240
++L FR+A+R+LLG + + L E +++ N+FSLP+D+PFSG RG++AR
Sbjct: 181 VKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKAR 240
Query: 241 QILQKGLEKAIREKL----QCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFA 296
++ +E+ IR K+ G+ DAL LLIE S E G+ + MQ LK + EL+F
Sbjct: 241 NLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFG 300
Query: 297 AYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDC 356
+ TTASA+TSLI L +P VL+K+R+EL++ G+L + L ++ L L+Y+ C
Sbjct: 301 GHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSN--QDNKLDMEILEQLKYIGC 358
Query: 357 VIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDR 416
VIKE +RL P+ GG+R L+TFEL+G+QIPKGW+V+YSI DTHD A +F + F+PDR
Sbjct: 359 VIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDR 418
Query: 417 FSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITL 476
F ED RF ++PFGGG+R+C+GK AK+ LK+ VELA ++L P +
Sbjct: 419 FMLPHPEDA-SRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGP-PTMKT 476
Query: 477 VPVLHPVDGLSVKF 490
P ++PVD L +F
Sbjct: 477 SPTVYPVDNLPARF 490
>gi|16933528 cytochrome P450, family 26, subfamily A, polypeptide 1
isoform 2 [Homo sapiens]
Length = 428
Score = 354 bits (909), Expect = 9e-98
Identities = 189/424 (44%), Positives = 269/424 (63%), Gaps = 13/424 (3%)
Query: 76 RREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIG 135
+R KYG ++KTHL GRP +RV GA+NVR+IL+GEH LVS WP S R +LG +SN
Sbjct: 2 KRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHD 61
Query: 136 DIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPE-AINVYQEAQKLTFRMAI 194
H+ ++KV + FS EALE Y+P I + +L W S E + VY E ++L FR+A+
Sbjct: 62 SSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAM 121
Query: 195 RVLLG----FSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQARQILQKGLEKA 250
R+LLG + + L E +++ N+FSLP+D+PFSG RG++AR ++ +E+
Sbjct: 122 RILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQN 181
Query: 251 IREKL----QCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASAST 306
IR K+ G+ DAL LLIE S E G+ + MQ LK + EL+F + TTASA+T
Sbjct: 182 IRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAAT 241
Query: 307 SLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFT 366
SLI L +P VL+K+R+EL++ G+L + L ++ L L+Y+ CVIKE +RL
Sbjct: 242 SLITYLGLYPHVLQKVREELKSKGLLCKSN--QDNKLDMEILEQLKYIGCVIKETLRLNP 299
Query: 367 PISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKD 426
P+ GG+R L+TFEL+G+QIPKGW+V+YSI DTHD A +F + F+PDRF ED
Sbjct: 300 PVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDA- 358
Query: 427 GRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGL 486
RF ++PFGGG+R+C+GK AK+ LK+ VELA ++L P + P ++PVD L
Sbjct: 359 SRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGP-PTMKTSPTVYPVDNL 417
Query: 487 SVKF 490
+F
Sbjct: 418 PARF 421
>gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide 43
isoform 2 [Homo sapiens]
Length = 503
Score = 114 bits (284), Expect = 3e-25
Identities = 116/474 (24%), Positives = 216/474 (45%), Gaps = 46/474 (9%)
Query: 46 KLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKI 105
KL IP G P +G +L F EKYG ++ + +P++ + + ++ +
Sbjct: 35 KLGIP-GPTPLPFLGTILFYLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTV 93
Query: 106 LMGEHHLVSTEWPRSTRMLLGP-----NTVSNSIGDIHRNKRKVFSKIFSHEALESYLPK 160
L+ E + V T +M LGP + +S + + + R + S F+ + +P
Sbjct: 94 LVKECYSVFTN-----QMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPI 148
Query: 161 IQL---VIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSI-----PEED-LGHLF 211
I ++ +LR + + ++IN+ T + L G ++ P++ L ++
Sbjct: 149 ISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMK 208
Query: 212 EVYQQFVDNVFSLPVDL------PFSGYRRGIQARQI---LQKGLEKAIREKLQCTQGKD 262
++ + + F L + L F G+ + + L+ +E+ +L+ Q K
Sbjct: 209 KLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQ-KH 267
Query: 263 YLDALDLLIES-----SKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPT 317
+D +I+S +K H K ++ EL ++ +IFAAY TT++ ++ +L HP
Sbjct: 268 RVDFFQQMIDSQNSKETKSH-KALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPD 326
Query: 318 VLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQ 377
V +KL++E+ A P + + D L + YLD V+ E +RLF +S R +
Sbjct: 327 VQQKLQEEIDAV-------LPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKK 379
Query: 378 TFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGG 437
E++G IPKG +VM I H + + F P+RFS+ +++D + Y+PFG G
Sbjct: 380 DIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK-KNKDSIDLYRYIPFGAG 438
Query: 438 VRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITL--VPVLHPVDGLSVK 489
R C+G A +K+ + F+ T + L +P+L P + +K
Sbjct: 439 PRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPILQPEKPIVLK 492
>gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide 43
isoform 1 [Homo sapiens]
Length = 504
Score = 109 bits (273), Expect = 5e-24
Identities = 113/474 (23%), Positives = 212/474 (44%), Gaps = 45/474 (9%)
Query: 46 KLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKI 105
KL IP G P +G +L F EKYG ++ + +P++ + + ++ +
Sbjct: 35 KLGIP-GPTPLPFLGTILFYLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTV 93
Query: 106 LMGEHHLVSTEWPRSTRMLLGP-----NTVSNSIGDIHRNKRKVFSKIFSHEALESYLPK 160
L+ E + V T +M LGP + +S + + + R + S F+ + +P
Sbjct: 94 LVKECYSVFTN-----QMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPI 148
Query: 161 IQL---VIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSI-----PEED-LGHLF 211
I ++ +LR + + ++IN+ T + L G ++ P++ L ++
Sbjct: 149 ISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMK 208
Query: 212 EVYQQFVDNVFSLPVDL------PFSGYRRGIQARQI---LQKGLEKAIREKLQCTQGKD 262
++ + + F L + L F G+ + + L+ +E+ +L+ Q K
Sbjct: 209 KLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQ-KH 267
Query: 263 YLDALDLLIES-----SKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPT 317
+D +I+S +K H K ++ EL ++ +IFAAY TT++ ++ +L HP
Sbjct: 268 RVDFFQQMIDSQNSKETKSH-KALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPD 326
Query: 318 VLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQ 377
V +KL++E+ A P + + D L + YLD V+ E +RLF +S R +
Sbjct: 327 VQQKLQEEIDAV-------LPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKK 379
Query: 378 TFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGG 437
E++G IPKG +VM I H + + F P+ +++D + Y+PFG G
Sbjct: 380 DIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAG 439
Query: 438 VRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITL--VPVLHPVDGLSVK 489
R C+G A +K+ + F+ T + L +P+L P + +K
Sbjct: 440 PRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPILQPEKPIVLK 493
>gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7
[Homo sapiens]
Length = 503
Score = 107 bits (267), Expect = 3e-23
Identities = 131/502 (26%), Positives = 205/502 (40%), Gaps = 68/502 (13%)
Query: 6 LDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGET--- 62
+DL+ LA V LLLAVS L L T KL IP G P +G
Sbjct: 1 MDLIPNLA------VETWLLLAVSLILLYLYGTRTHGLFKKLGIP-GPTPLPFLGNALSF 53
Query: 63 --GHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRS 120
G+W F +KY V+ + +P++ +T + ++ +L+ E + V T
Sbjct: 54 RKGYWT-----FDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTN---- 104
Query: 121 TRMLLGP-----NTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQL---VIQDTLRAW 172
R GP N +S + + + R + S F+ L+ +P I V+ LR
Sbjct: 105 -RRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRE 163
Query: 173 SSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSG 232
+ + + + + + G SI L FV+N L P
Sbjct: 164 AETGKPVTLKHVFGAYSMDVITSTSFGVSIDS-----LNNPQDPFVENTKKLLRFNPLDP 218
Query: 233 YRRGIQARQILQKGLE-------------------KAIRE-KLQCTQGKDYLDALDLLIE 272
+ I+ L LE K I+E +L+ TQ K +D L L+I+
Sbjct: 219 FVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQ-KHRVDFLQLMID 277
Query: 273 SSK----EHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRA 328
S E K ++ EL ++ IFA Y TT+S + +I +L HP V +K++ E+
Sbjct: 278 SQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDT 337
Query: 329 HGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPK 388
P + DT+ L YLD V+ E +RLF R + E++G IPK
Sbjct: 338 V-------LPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPK 390
Query: 389 GWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAK 448
G VM H + + F P+RFS+ +++D + Y PFG G R C+G A
Sbjct: 391 GVVVMIPSYVLHHDPKYWTEPEKFLPERFSK-KNKDNIDPYIYTPFGSGPRNCIGMRFAL 449
Query: 449 LFLKVLAVELASTSRFELATRT 470
+ +K+ V + F+ T
Sbjct: 450 VNMKLALVRVLQNFSFKPCKET 471
>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
[Homo sapiens]
Length = 502
Score = 106 bits (264), Expect = 6e-23
Identities = 124/494 (25%), Positives = 207/494 (41%), Gaps = 53/494 (10%)
Query: 6 LDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHW 65
+DL+ LA V LLLAVS L L T +L IP G PL+G +
Sbjct: 1 MDLIPNLA------VETWLLLAVSLVLLYLYGTRTHGLFKRLGIP-GPTPLPLLGNVLSY 53
Query: 66 LLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLL 125
F + +KYG ++ T+ P++ +T + +R +L+ E + V T R L
Sbjct: 54 RQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTN-----RRSL 108
Query: 126 GP-----NTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQL---VIQDTLRAWSSHPE 177
GP + +S + + + R + S F+ L+ P I V+ LR + +
Sbjct: 109 GPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGK 168
Query: 178 AINVYQEAQKLTFRMAIRVLLGFSI-----PEEDLGHLFEVYQQF--VDNVFSLPVDLPF 230
+ + + + G +I P++ + + +F +D +F + PF
Sbjct: 169 PVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPF 228
Query: 231 SGYRRGIQARQI----------LQKGLEKAIREKLQCTQGKDYLDALDLLIESSK----E 276
+A + L K + + + +L Q K LD L L+I+S E
Sbjct: 229 --LTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQ-KHRLDFLQLMIDSQNSKETE 285
Query: 277 HGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGG 336
K ++ EL ++ IFA Y TT+S + + +L HP V +KL+ E+ A
Sbjct: 286 SHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAV------- 338
Query: 337 CPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSI 396
P + D + + YLD V+ E +RLF RT + E++G IPKG V+
Sbjct: 339 LPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPT 398
Query: 397 RDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAV 456
H + + F P+RFS + +D + Y PFG G R C+G A + +K+ +
Sbjct: 399 YALHHDPKYWTEPEEFRPERFS--KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALI 456
Query: 457 ELASTSRFELATRT 470
+ F+ T
Sbjct: 457 RVLQNFSFKPCKET 470
>gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide 4
[Homo sapiens]
Length = 503
Score = 105 bits (261), Expect = 1e-22
Identities = 117/486 (24%), Positives = 204/486 (41%), Gaps = 42/486 (8%)
Query: 12 LATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSG 71
+A + + LLLAVS L L + KL IP G P +G +
Sbjct: 1 MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIP-GPTPLPFLGNILSYHKGFCM 59
Query: 72 FQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGP---- 127
F +KYG V+ + +P++ +T + ++ +L+ E + V T R GP
Sbjct: 60 FDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTN-----RRPFGPVGFM 114
Query: 128 -NTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQL---VIQDTLRAWSSHPEAINVYQ 183
+ +S + + + R + S F+ L+ +P I V+ LR + + + +
Sbjct: 115 KSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKD 174
Query: 184 EAQKLTFRMAIRVLLGFSIPE---------EDLGHL--FEVYQQFVDNVFSLPVDLPFSG 232
+ + G +I E+ L F+ F ++ P +P
Sbjct: 175 VFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILE 234
Query: 233 YRRGI----QARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSK----EHGKEMTMQ 284
+ L+K +++ +L+ TQ K +D L L+I+S E K ++
Sbjct: 235 VLNICVFPREVTNFLRKSVKRMKESRLEDTQ-KHRVDFLQLMIDSQNSKETESHKALSDL 293
Query: 285 ELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLR 344
EL ++ IFA Y TT+S + ++ +L HP V +KL++E+ A P +
Sbjct: 294 ELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAV-------LPNKAPPT 346
Query: 345 LDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAP 404
DT+ + YLD V+ E +RLF R + E++G IPKG VM H
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPK 406
Query: 405 VFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRF 464
+ + F P+RFS+ +++D + Y PFG G R C+G A + +K+ + + F
Sbjct: 407 YWTEPEKFLPERFSK-KNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 465
Query: 465 ELATRT 470
+ T
Sbjct: 466 KPCKET 471
>gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide 22
[Homo sapiens]
Length = 519
Score = 102 bits (253), Expect = 1e-21
Identities = 79/244 (32%), Positives = 124/244 (50%), Gaps = 24/244 (9%)
Query: 241 QILQKGLEKAIREK---LQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAA 297
Q++Q L KA +K L+ + K +LD LD+L+ + E+G ++ ++L+ +F
Sbjct: 265 QVIQ--LRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEG 322
Query: 298 YATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCV 357
+ TTAS + ++ L HP E+ R+E+ HG+L G ++ + L + Y
Sbjct: 323 HDTTASGISWILYALATHPKHQERCREEI--HGLLGDG-----ASITWNHLDQMPYTTMC 375
Query: 358 IKEVMRLFTPISGGYRTVLQ--TFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPD 415
IKE +RL+ P+ G R + TF DG +PKG V+ SI H V+ ++ VFDP
Sbjct: 376 IKEALRLYPPVPGIGRELSTPVTFP-DGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPS 434
Query: 416 RFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRIT 475
RF+ ++ +LPF GG R C+GK A LKV + RFEL P T
Sbjct: 435 RFAPGSAQHSHA---FLPFSGGSRNCIGKQFAMNQLKV--ARALTLLRFEL----LPDPT 485
Query: 476 LVPV 479
+P+
Sbjct: 486 RIPI 489
>gi|4503243 cytochrome P450, family 51, subfamily A, polypeptide 1
isoform 1 [Homo sapiens]
Length = 509
Score = 98.2 bits (243), Expect = 2e-20
Identities = 98/438 (22%), Positives = 187/438 (42%), Gaps = 21/438 (4%)
Query: 63 GHWLLQGSG---FQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTE--W 117
GH + G F + EKYG VF ++G+ + G++ + ++ ++ E +
Sbjct: 78 GHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVY 137
Query: 118 PRSTRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPE 177
R T + G + + ++K+ + + ++ I+ ++ +W E
Sbjct: 138 SRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGE 197
Query: 178 AINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFS-----LPVDLPFSG 232
NV++ +L A L G I + + ++Y +D FS LP LP
Sbjct: 198 K-NVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYAD-LDGGFSHAAWLLPGWLPLPS 255
Query: 233 YRRGIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLE 292
+RR +A + ++ KAI+++ Q + D D L L++++ + G+ +T E+ +
Sbjct: 256 FRRRDRAHREIKDIFYKAIQKRRQSQEKID--DILQTLLDATYKDGRPLTDDEVAGMLIG 313
Query: 293 LIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLR 352
L+ A T+++ S + L + T+ +K E + + P L D L L
Sbjct: 314 LLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKT---VCGENLP---PLTYDQLKDLN 367
Query: 353 YLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVF 412
LD IKE +RL PI R + G+ IP G V S + + F
Sbjct: 368 LLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDF 427
Query: 413 DPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFP 472
+PDR+ Q + +F Y+PFG G C+G++ A + +K + + F+L FP
Sbjct: 428 NPDRYLQDNPASGE-KFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFP 486
Query: 473 RITLVPVLHPVDGLSVKF 490
+ ++H + +++
Sbjct: 487 TVNYTTMIHTPENPVIRY 504
>gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide 11
[Homo sapiens]
Length = 519
Score = 97.8 bits (242), Expect = 2e-20
Identities = 81/254 (31%), Positives = 127/254 (50%), Gaps = 26/254 (10%)
Query: 241 QILQKGLEKAIREK---LQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAA 297
Q++Q L KA +K L+ + K +LD LD+L+ + E+G ++ ++L+ +F
Sbjct: 265 QVIQ--LRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEG 322
Query: 298 YATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCV 357
+ TTAS + ++ L HP E+ R+E+ H +L G ++ + L + Y
Sbjct: 323 HDTTASGISWILYALATHPKHQERCREEI--HSLLGDG-----ASITWNHLDQMPYTTMC 375
Query: 358 IKEVMRLFTPISGGYRTVLQ--TFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPD 415
IKE +RL+ P+ G R + TF DG +PKG V+ SI H V+ + VFDP
Sbjct: 376 IKEALRLYPPVPGIGRELSTPVTFP-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPF 434
Query: 416 RFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRIT 475
RF+ ++ +LPF GG R C+GK A LKV + RFEL P T
Sbjct: 435 RFAPGSAQHSHA---FLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFEL----LPDPT 485
Query: 476 LVPVLHPVDGLSVK 489
+P+ P+ L +K
Sbjct: 486 RIPI--PIARLVLK 497
>gi|30023836 cytochrome P450 4Z1 [Homo sapiens]
Length = 505
Score = 95.1 bits (235), Expect = 1e-19
Identities = 71/222 (31%), Positives = 121/222 (54%), Gaps = 12/222 (5%)
Query: 248 EKAIREKL-QCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASAST 306
++++++KL Q T K D LD+L+ + E+ K+ + +L+ +FA + TT+SA +
Sbjct: 265 KESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAIS 324
Query: 307 SLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFT 366
++ L K+P ++ RDE+R +L G ++ + LS + Y IKE +RL+
Sbjct: 325 WILYCLAKYPEHQQRCRDEIRE--LLGDG-----SSITWEHLSQMPYTTMCIKECLRLYA 377
Query: 367 PISGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDK 425
P+ R + + DG +P G +V +I H ++D VF+P RFS+ SE K
Sbjct: 378 PVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSE-K 436
Query: 426 DGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELA 467
+ ++PF G+R C+G+H A + KV AV L + RF+LA
Sbjct: 437 IHPYAFIPFSAGLRNCIGQHFAIIECKV-AVAL-TLLRFKLA 476
>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
[Homo sapiens]
Length = 524
Score = 93.2 bits (230), Expect = 5e-19
Identities = 74/234 (31%), Positives = 113/234 (48%), Gaps = 8/234 (3%)
Query: 264 LDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLR 323
LD +D+L+ S E GKE++ ++++ +F + TTAS + ++ L KHP E+ R
Sbjct: 296 LDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCR 355
Query: 324 DELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFEL-D 382
E++ L P E + D L+ L +L IKE +RL P+ R Q F L D
Sbjct: 356 QEVQE---LLKDREPIE--IEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPD 410
Query: 383 GFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCL 442
G IPKG + +I H V+ D V+DP RF Q +++ ++PF G R C+
Sbjct: 411 GRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKER-SPLAFIPFSAGPRNCI 469
Query: 443 GKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGLDSN 496
G+ A +KV+ R L T T PR +L GL ++ L +N
Sbjct: 470 GQAFAMAEMKVVLALTLLHFRI-LPTHTEPRRKPELILRAEGGLWLRVEPLGAN 522
>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
[Homo sapiens]
Length = 524
Score = 93.2 bits (230), Expect = 5e-19
Identities = 74/234 (31%), Positives = 113/234 (48%), Gaps = 8/234 (3%)
Query: 264 LDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLR 323
LD +D+L+ S E GKE++ ++++ +F + TTAS + ++ L KHP E+ R
Sbjct: 296 LDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCR 355
Query: 324 DELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFEL-D 382
E++ L P E + D L+ L +L IKE +RL P+ R Q F L D
Sbjct: 356 QEVQE---LLKDREPIE--IEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPD 410
Query: 383 GFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCL 442
G IPKG + +I H V+ D V+DP RF Q +++ ++PF G R C+
Sbjct: 411 GRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKER-SPLAFIPFSAGPRNCI 469
Query: 443 GKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGLDSN 496
G+ A +KV+ R L T T PR +L GL ++ L +N
Sbjct: 470 GQAFAMAEMKVVLALTLLHFRI-LPTHTEPRRKPELILRAEGGLWLRVEPLGAN 522
>gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide 2
[Homo sapiens]
Length = 525
Score = 92.8 bits (229), Expect = 7e-19
Identities = 107/479 (22%), Positives = 199/479 (41%), Gaps = 53/479 (11%)
Query: 13 ATLAACLVSVTLLLAVSQQL--WQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGS 70
A A L +L+L++ Q++ + +W R PIP + +PL+G G
Sbjct: 18 AASALSLAGASLVLSLLQRVASYARKWQQMR------PIPTVARAYPLVGHALLMKPDGR 71
Query: 71 GF-----QSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLL 125
F + + ++ + K + P++ + AENV IL + + + L
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 126 GPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSH--PEAINVYQ 183
G ++ S G+ R++RK+ + F LE +L + ++ H EA N +
Sbjct: 132 GLGLLT-STGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFF 190
Query: 184 EAQKLTFRMAIRVLLGFSI---PEEDLGHLFEVYQ--QFVDNVFSLP---VDLPFSGYRR 235
+ +G +I +D ++ VY+ + + +P +DL + ++
Sbjct: 191 YITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKE 250
Query: 236 GIQAR---QILQKGLEKAIREKLQCTQGKDYLDA---------------LDLLIESSKEH 277
G + + QIL I E+ + LDLL+ + +
Sbjct: 251 GWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDE 310
Query: 278 GKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGC 337
G ++ +++++ +F + TTA+A + L +P V +K+ EL +
Sbjct: 311 GNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHEL--DDVFGKSDR 368
Query: 338 PCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIR 397
P ++ L LRYL+CVIKE +RLF + R+V + E+ G+++ KG +
Sbjct: 369 PAT----VEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPY 424
Query: 398 DTHDTAPVFKDVNVFDPDRFSQARSEDKDGR--FHYLPFGGGVRTCLGKHLAKLFLKVL 454
H F + F P+RF E+ GR + Y+PF G R C+G+ A + K +
Sbjct: 425 ALHRDPRYFPNPEEFQPERFF---PENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTI 480
>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide 12
[Homo sapiens]
Length = 524
Score = 91.7 bits (226), Expect = 1e-18
Identities = 98/380 (25%), Positives = 158/380 (41%), Gaps = 36/380 (9%)
Query: 135 GDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAW----SSHPEAINVYQEAQKLTF 190
GD R++ + F L+SY+ L W S +++++ +T
Sbjct: 141 GDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTL 200
Query: 191 RMAIRVLLGFSI-----PEE------DLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQA 239
+ + F P E +L L E Q + L G RR +A
Sbjct: 201 DSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLYYLSHDG-RRFHRA 259
Query: 240 RQILQKGLEKAIREKLQC--TQGKD----------YLDALDLLIESSKEHGKEMTMQELK 287
+++ + IRE+ + TQG D LD +D+L+ S E GK ++ ++++
Sbjct: 260 CRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIR 319
Query: 288 DGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDT 347
+F + TTAS + ++ L +HP E+ R E++ L P E + D
Sbjct: 320 AEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE---LLKDRDPKE--IEWDD 374
Query: 348 LSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVF 406
L+ L +L +KE +RL P R Q L DG IPKG + + I H V+
Sbjct: 375 LAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW 434
Query: 407 KDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFEL 466
D V+DP RF S+ + ++PF G R C+G+ A +KV+ + RF L
Sbjct: 435 PDPEVYDPFRFDPENSKGR-SPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF-L 492
Query: 467 ATRTFPRITLVPVLHPVDGL 486
T PR L ++ GL
Sbjct: 493 PDHTEPRRKLELIMRAEGGL 512
>gi|5729796 cytochrome P450, family 46 [Homo sapiens]
Length = 500
Score = 90.1 bits (222), Expect = 4e-18
Identities = 98/410 (23%), Positives = 176/410 (42%), Gaps = 37/410 (9%)
Query: 78 EKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRM-----LLGPNTVSN 132
+KYG V + ++ + + VT E+V+K LM + ++ R+ + L G VS
Sbjct: 69 KKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSE 128
Query: 133 SIGDIHRNKRKVFSKIFSHEALESYLPKI-----QLVIQDTLRAWSSHPEAIN------V 181
+ +R+V FS +L S + QLV +A P ++
Sbjct: 129 CNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTA 188
Query: 182 YQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQA-- 239
K F M +LLG P L + + + +L LP G R+ ++
Sbjct: 189 MDILAKAAFGMETSMLLGAQKPLSQAVKL--MLEGITASRNTLAKFLP--GKRKQLREVR 244
Query: 240 ---RQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFA 296
R + Q G + R + +G++ D+L + K + L D + A
Sbjct: 245 ESIRFLRQVGRDWVQRRREALKRGEEV--PADILTQILKAEEGAQDDEGLLDNFVTFFIA 302
Query: 297 AYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDC 356
+ T+A+ +M+L + P ++ +L+ E+ ++ S + L + L L+YL
Sbjct: 303 GHETSANHLAFTVMELSRQPEIVARLQAEVDE--VIGS-----KRYLDFEDLGRLQYLSQ 355
Query: 357 VIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDR 416
V+KE +RL+ P G +R + + +DG ++P +++S F+D F+PDR
Sbjct: 356 VLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDR 415
Query: 417 FSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFEL 466
F + RF Y PF G R+C+G+ A++ +KV+ +L F L
Sbjct: 416 FGPGAPKP---RFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRL 462
>gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide 3
[Homo sapiens]
Length = 520
Score = 90.1 bits (222), Expect = 4e-18
Identities = 63/207 (30%), Positives = 102/207 (49%), Gaps = 7/207 (3%)
Query: 249 KAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSL 308
+ + + LQ LD +D+L+ S E GK+++ ++++ +F + TTAS + +
Sbjct: 281 QGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWV 340
Query: 309 IMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPI 368
+ L KHP E+ R E++ L P E + D L+ L +L IKE +RL P+
Sbjct: 341 LYHLAKHPEYQERCRQEVQE---LLKDREPKE--IEWDDLAQLPFLTMCIKESLRLHPPV 395
Query: 369 SGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDG 427
R Q L DG IPKG + S+ TH V+ D V+DP RF +++
Sbjct: 396 PAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKER-S 454
Query: 428 RFHYLPFGGGVRTCLGKHLAKLFLKVL 454
++PF G R C+G+ A +KV+
Sbjct: 455 PLAFIPFSAGPRNCIGQAFAMAEMKVV 481
>gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide 22
[Homo sapiens]
Length = 531
Score = 90.1 bits (222), Expect = 4e-18
Identities = 75/253 (29%), Positives = 124/253 (49%), Gaps = 16/253 (6%)
Query: 240 RQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYA 299
R + Q+G E ++ K QGK LD +D+L+ + E GKE++ ++++ +F +
Sbjct: 284 RALRQQGAEAWLKAK----QGKT-LDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHD 338
Query: 300 TTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIK 359
TT+S + ++ L K+P EK R+E++ G E L D L+ L + IK
Sbjct: 339 TTSSGISWMLFNLAKYPEYQEKCREEIQE----VMKGRELE-ELEWDDLTQLPFTTMCIK 393
Query: 360 EVMRLFTPISGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFS 418
E +R + P++ R + +L DG IPKG + SI TH V+ D V++P RF
Sbjct: 394 ESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFD 453
Query: 419 QARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVP 478
+ + Y+PF G R C+G+ A L+V V + RF L+ ++ P
Sbjct: 454 PDNPQQR-SPLAYVPFSAGPRNCIGQSFAMAELRV--VVALTLLRFRLSVDRTRKVRRKP 510
Query: 479 --VLHPVDGLSVK 489
+L +GL +K
Sbjct: 511 ELILRTENGLWLK 523
>gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide 2
[Homo sapiens]
Length = 520
Score = 89.4 bits (220), Expect = 7e-18
Identities = 76/241 (31%), Positives = 116/241 (48%), Gaps = 12/241 (4%)
Query: 249 KAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSL 308
+ + + LQ LD +D+L+ S E GK+++ ++++ +F + TTAS + +
Sbjct: 281 QGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWV 340
Query: 309 IMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPI 368
+ L KHP E+ R E++ L P E + D L+ L +L +KE +RL P+
Sbjct: 341 LYHLAKHPEYQERCRQEVQE---LLKDREPKE--IEWDDLAHLPFLTMCMKESLRLHPPV 395
Query: 369 SGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDG 427
R V Q L DG IPKG + S+ TH V+ D V+DP RF +++
Sbjct: 396 PVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKER-S 454
Query: 428 RFHYLPFGGGVRTCLGKHLAKLFLK-VLAVELASTSRFE-LATRTFPRITLVPVLHPVDG 485
++PF G R C+G+ A +K VLA+ L RF L T PR VL G
Sbjct: 455 PLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLL---RFRVLPDHTEPRRKPELVLRAEGG 511
Query: 486 L 486
L
Sbjct: 512 L 512
>gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide 1
[Homo sapiens]
Length = 509
Score = 87.8 bits (216), Expect = 2e-17
Identities = 63/211 (29%), Positives = 103/211 (48%), Gaps = 11/211 (5%)
Query: 244 QKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTAS 303
+K L+ +++ T + Y D LD+++ + E G + ++ + A + T A+
Sbjct: 266 KKSLQAGVKQ--DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAA 323
Query: 304 ASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMR 363
+ + ++ L +P E+ R+E+R GIL G ++ D L + Y IKE R
Sbjct: 324 SISWILYCLALNPEHQERCREEVR--GILGDGS-----SITWDQLGEMSYTTMCIKETCR 376
Query: 364 LFTPISGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARS 422
L + R + + DG +P G +V+ SI H V+K+ VFDP RFSQ S
Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 436
Query: 423 EDKDGRFHYLPFGGGVRTCLGKHLAKLFLKV 453
D+ + YLPF G R C+G+ A + LKV
Sbjct: 437 -DQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466
>gi|225903399 cytochrome P450, family 51, subfamily A, polypeptide 1
isoform 2 [Homo sapiens]
Length = 404
Score = 86.7 bits (213), Expect = 5e-17
Identities = 88/410 (21%), Positives = 175/410 (42%), Gaps = 18/410 (4%)
Query: 88 LLGRPLIRVTGAENVRKILMGEHHLVSTE--WPRSTRMLLGPNTVSNSIGDIHRNKRKVF 145
++G+ + G++ + ++ ++ E + R T + G + + ++K+
Sbjct: 1 MVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKML 60
Query: 146 SKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEE 205
+ + ++ I+ ++ +W E NV++ +L A L G I +
Sbjct: 61 KSGLNIAHFKQHVSIIEKETKEYFESWGESGEK-NVFEALSELIILTASHCLHGKEIRSQ 119
Query: 206 DLGHLFEVYQQFVDNVFS-----LPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQG 260
+ ++Y +D FS LP LP +RR +A + ++ KAI+++ Q +
Sbjct: 120 LNEKVAQLYAD-LDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEK 178
Query: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320
D D L L++++ + G+ +T E+ + L+ A T+++ S + L + T+ +
Sbjct: 179 ID--DILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQK 236
Query: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380
K E + + P L D L L LD IKE +RL PI R
Sbjct: 237 KCYLEQKT---VCGENLP---PLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQT 290
Query: 381 LDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRT 440
+ G+ IP G V S + + F+PDR+ Q + +F Y+PFG G
Sbjct: 291 VAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGE-KFAYVPFGAGRHR 349
Query: 441 CLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKF 490
C+G++ A + +K + + F+L FP + ++H + +++
Sbjct: 350 CIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRY 399
>gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8
[Homo sapiens]
Length = 520
Score = 85.1 bits (209), Expect = 1e-16
Identities = 75/241 (31%), Positives = 114/241 (47%), Gaps = 12/241 (4%)
Query: 249 KAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSL 308
+ + + LQ LD +D+L+ S ++GKE++ ++++ +F + TTAS + +
Sbjct: 281 QGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWV 340
Query: 309 IMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPI 368
+ L +HP E+ R E++ L P E + D L+ L +L +KE +RL PI
Sbjct: 341 LYNLARHPEYQERCRQEVQE---LLKDREPKE--IEWDDLAQLPFLTMCLKESLRLHPPI 395
Query: 369 SGGYRTVLQTFEL-DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDG 427
R Q L D IPKG +I H V+ D V+DP RF ++ K
Sbjct: 396 PTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQ-KRS 454
Query: 428 RFHYLPFGGGVRTCLGKHLAKLFLK-VLAVELASTSRFE-LATRTFPRITLVPVLHPVDG 485
++PF G R C+G+ A +K VLA+ L RF L PR T VL DG
Sbjct: 455 PMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLL---RFRILPDHREPRRTPEIVLRAEDG 511
Query: 486 L 486
L
Sbjct: 512 L 512
>gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide 43
isoform 3 [Homo sapiens]
Length = 420
Score = 84.3 bits (207), Expect = 2e-16
Identities = 96/399 (24%), Positives = 180/399 (45%), Gaps = 43/399 (10%)
Query: 46 KLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKI 105
KL IP G P +G +L F EKYG ++ + +P++ + + ++ +
Sbjct: 35 KLGIP-GPTPLPFLGTILFYLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTV 93
Query: 106 LMGEHHLVSTEWPRSTRMLLGP-----NTVSNSIGDIHRNKRKVFSKIFSHEALESYLPK 160
L+ E + V T +M LGP + +S + + + R + S F+ + +P
Sbjct: 94 LVKECYSVFTN-----QMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPI 148
Query: 161 IQL---VIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSI-----PEED-LGHLF 211
I ++ +LR + + ++IN+ T + L G ++ P++ L ++
Sbjct: 149 ISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMK 208
Query: 212 EVYQQFVDNVFSLPVDL------PFSGYRRGIQARQI---LQKGLEKAIREKLQCTQGKD 262
++ + + F L + L F G+ + + L+ +E+ +L+ Q K
Sbjct: 209 KLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQ-KH 267
Query: 263 YLDALDLLIES-----SKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPT 317
+D +I+S +K H K ++ EL ++ +IFAAY TT++ ++ +L HP
Sbjct: 268 RVDFFQQMIDSQNSKETKSH-KALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPD 326
Query: 318 VLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQ 377
V +KL++E+ A P + + D L + YLD V+ E +RLF +S R +
Sbjct: 327 VQQKLQEEIDAV-------LPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKK 379
Query: 378 TFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDR 416
E++G IPKG +VM I H + + F P+R
Sbjct: 380 DIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 418
>gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide 1
isoform a [Homo sapiens]
Length = 512
Score = 79.3 bits (194), Expect = 8e-15
Identities = 67/250 (26%), Positives = 111/250 (44%), Gaps = 20/250 (8%)
Query: 234 RRGIQARQILQKGLEKAIREKLQCTQ---------GKDYLDALDLLIESSKEHGKEMTMQ 284
RR ++A Q+ ++ IRE+ Q + +LD LD+L+ + E +++
Sbjct: 245 RRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDA 304
Query: 285 ELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLR 344
+L+ +F + TT S + + + +P + R+E+R IL + +
Sbjct: 305 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVRE--ILGD-----QDFFQ 357
Query: 345 LDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQ--TFELDGFQIPKGWSVMYSIRDTHDT 402
D L + YL IKE RL+ P+ YR + + TF +DG +P G + I H
Sbjct: 358 WDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VDGRSLPAGSLISMHIYALHRN 416
Query: 403 APVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTS 462
+ V+ D VFD RFS + K F ++PF G R C+G+ A +KV+
Sbjct: 417 SAVWPDPEVFDSLRFS-TENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRF 475
Query: 463 RFELATRTFP 472
F L P
Sbjct: 476 EFSLDPSRLP 485
>gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide 1
isoform b [Homo sapiens]
Length = 511
Score = 79.3 bits (194), Expect = 8e-15
Identities = 67/250 (26%), Positives = 111/250 (44%), Gaps = 20/250 (8%)
Query: 234 RRGIQARQILQKGLEKAIREKLQCTQ---------GKDYLDALDLLIESSKEHGKEMTMQ 284
RR ++A Q+ ++ IRE+ Q + +LD LD+L+ + E +++
Sbjct: 244 RRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDA 303
Query: 285 ELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLR 344
+L+ +F + TT S + + + +P + R+E+R IL + +
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVRE--ILGD-----QDFFQ 356
Query: 345 LDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQ--TFELDGFQIPKGWSVMYSIRDTHDT 402
D L + YL IKE RL+ P+ YR + + TF +DG +P G + I H
Sbjct: 357 WDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VDGRSLPAGSLISMHIYALHRN 415
Query: 403 APVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTS 462
+ V+ D VFD RFS + K F ++PF G R C+G+ A +KV+
Sbjct: 416 SAVWPDPEVFDSLRFS-TENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRF 474
Query: 463 RFELATRTFP 472
F L P
Sbjct: 475 EFSLDPSRLP 484
>gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide 1
[Homo sapiens]
Length = 501
Score = 79.0 bits (193), Expect = 1e-14
Identities = 116/512 (22%), Positives = 204/512 (39%), Gaps = 68/512 (13%)
Query: 13 ATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSG- 71
A L L + L V Q L Q R + P G G P IG + L S
Sbjct: 12 AALGGALFLLLFALGVRQLLKQRR---------PMGFPPGPPGLPFIGNI--YSLAASSE 60
Query: 72 ----FQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTE--WPRSTRMLL 125
+ + + YG +F L G + + G + V++ L+ + + + P +M
Sbjct: 61 LPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTK 120
Query: 126 GPNTVSNSIGDIHRNKRKVFSKIFSH-----EALESYLPKIQLVIQDTLRAWSSHPEAIN 180
+++ G + R++ F + ++ ES + + D + + P +
Sbjct: 121 MGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRP--FD 178
Query: 181 VYQEAQKLTFRMAIRVLLG--FSIPEEDLGHLFEVYQQ----------FVDNVFSLPVDL 228
Q + ++ G F+ + D H+ E++ + F+ N F L
Sbjct: 179 FKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGIL 238
Query: 229 PFSG----YRRGIQARQILQKGLEKA-IREKLQCTQGKDYLDA-LDLLIESSKEHGKEMT 282
PF +R L + +EKA + K Q Q ++DA LD + + + +
Sbjct: 239 PFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQ--HFVDAYLDEMDQGKNDPSSTFS 296
Query: 283 MQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGT 342
+ L ELI A TT + I+ + +P + +++ E+ I+ G P
Sbjct: 297 KENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDL--IMGPNGKPS--- 351
Query: 343 LRLDTLSGLRYLDCVIKEVMRLFTPISGG-YRTVLQTFELDGFQIPKGWSVMYSIRDTHD 401
D + Y + V+ EV+R + G + + + G+ IPKG +V+ ++ H
Sbjct: 352 --WDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHF 409
Query: 402 TAPVFKDVNVFDPDRFSQARSEDKDGRF----HYLPFGGGVRTCLGKHLAKLFLKVLAVE 457
++D VF P+RF D G F +PF G R CLG+HLA+ +++
Sbjct: 410 DEKYWRDPEVFHPERFL-----DSSGYFAKKEALVPFSLGRRHCLGEHLAR--MEMFLFF 462
Query: 458 LASTSRFELATRTFPRITLVPVLHPVDGLSVK 489
A RF L FP LVP L P G++++
Sbjct: 463 TALLQRFHL---HFPH-ELVPDLKPRLGMTLQ 490
>gi|7949031 cytochrome P450, family 2, subfamily B, polypeptide 6
[Homo sapiens]
Length = 491
Score = 78.6 bits (192), Expect = 1e-14
Identities = 117/466 (25%), Positives = 191/466 (40%), Gaps = 54/466 (11%)
Query: 20 VSVTLLLAVSQQLWQL---RWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSR 76
+SV L LA+ L L R T D+ +P G PL+G +G R
Sbjct: 3 LSVLLFLALLTGLLLLLVQRHPNTHDR-----LPPGPRPLPLLGNLLQMDRRGLLKSFLR 57
Query: 77 -REKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIG 135
REKYG+VF HL RP++ + G E +R+ L+ + S R ++ P +
Sbjct: 58 FREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSG---RGKIAMVDPFFRGYGVI 114
Query: 136 DIHRNKRKVFSKIF----------SHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEA 185
+ N+ KV + E + Q +I++ ++ + + ++Q
Sbjct: 115 FANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQS- 173
Query: 186 QKLTFRMAIRVLLGFSIPEED---LGHLFEVYQQF--VDNVFSLPVDLPFSGYRRGIQ-A 239
+T + ++ G +D L L YQ F + +VF +L FSG+ + A
Sbjct: 174 --ITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL-FSGFLKYFPGA 230
Query: 240 RQILQKGLEKAI----------REKLQCTQGKDYLDALDLLIESSKEHG-KEMTMQELKD 288
+ + K L++ RE L + KD +D L +E K + E + Q L
Sbjct: 231 HRQVYKNLQEINAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNL 290
Query: 289 GTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTL 348
TL L FA TT++ + +LK+P V E++ E+ ++ P L
Sbjct: 291 NTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQ--VIGPHRPP-----ELHDR 343
Query: 349 SGLRYLDCVIKEVMRLFTPISGGY-RTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFK 407
+ + Y + VI E+ R + G V Q G+ IPK V + F+
Sbjct: 344 AKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFE 403
Query: 408 DVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAK--LFL 451
+ F+PD F A K ++PF G R CLG+ +A+ LFL
Sbjct: 404 KPDAFNPDHFLDANGALKKTE-AFIPFSLGKRICLGEGIARAELFL 448
>gi|13449277 cytochrome P450, family 2, subfamily S, polypeptide 1
[Homo sapiens]
Length = 504
Score = 77.8 bits (190), Expect = 2e-14
Identities = 63/199 (31%), Positives = 97/199 (48%), Gaps = 20/199 (10%)
Query: 261 KDYLDALDLLIESSKEH-GKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVL 319
+D +DA L + +++ G E T + + + L+FA T ++ ++ L+K+P V
Sbjct: 266 RDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQ 325
Query: 320 EKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGY-RTVLQT 378
+ +R+EL L +G P G + L Y D V+ E RL + G RT+++T
Sbjct: 326 KWVREELNRE--LGAGQAPSLGDR-----TRLPYTDAVLHEAQRLLALVPMGIPRTLMRT 378
Query: 379 FELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFH----YLPF 434
G+ +P+G V + +FK F+PDRF D DGRF +LPF
Sbjct: 379 TRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFL-----DADGRFRKHEAFLPF 433
Query: 435 GGGVRTCLGKHLAK--LFL 451
G R CLG+ LAK LFL
Sbjct: 434 SLGKRVCLGEGLAKAELFL 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,000,221
Number of Sequences: 37866
Number of extensions: 775089
Number of successful extensions: 1898
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1687
Number of HSP's gapped (non-prelim): 104
length of query: 512
length of database: 18,247,518
effective HSP length: 107
effective length of query: 405
effective length of database: 14,195,856
effective search space: 5749321680
effective search space used: 5749321680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.